548476:CAURI RS02145
gene id: 548476:CAURI_RS02145
uniprot id: C3PKQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

548476:CAURI RS06070
gene id: 548476:CAURI_RS06070
uniprot id: C3PFZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

548476:CAURI RS01815
gene id: 548476:CAURI_RS01815
uniprot id: C3PKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

548476:CAURI RS04385
gene id: 548476:CAURI_RS04385
uniprot id: C3PF23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

548476:CAURI RS12735
gene id: 548476:CAURI_RS12735
uniprot id: C3PKC7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

548476:CAURI RS06555
gene id: 548476:CAURI_RS06555
uniprot id: C3PG94
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

548476:CAURI RS08355
gene id: 548476:CAURI_RS08355
uniprot id: C3PH88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

548476:CAURI RS02665
gene id: 548476:CAURI_RS02665
uniprot id: C3PL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS07070
gene id: 548476:CAURI_RS07070
uniprot id: C3PGJ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

548476:CAURI RS05380
gene id: 548476:CAURI_RS05380
uniprot id: C3PFL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

548476:CAURI RS12055
gene id: 548476:CAURI_RS12055
uniprot id: C3PJK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

548476:CAURI RS08190
gene id: 548476:CAURI_RS08190
uniprot id: C3PH56
names: Similarity
messages: Belongs to the UPF0102 family.

548476:CAURI RS07215
gene id: 548476:CAURI_RS07215
uniprot id: C3PGL8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

548476:CAURI RS01790
gene id: 548476:CAURI_RS01790
uniprot id: C3PKI8
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS09080
gene id: 548476:CAURI_RS09080
uniprot id: C3PHN6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

548476:CAURI RS05905
gene id: 548476:CAURI_RS05905
uniprot id: C3PFX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

548476:CAURI RS02725
gene id: 548476:CAURI_RS02725
uniprot id: C3PLA1
names: Similarity
messages: Belongs to the pyruvate kinase family.

548476:CAURI RS02785
gene id: 548476:CAURI_RS02785
uniprot id: C3PLB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

548476:CAURI RS05700
gene id: 548476:CAURI_RS05700
uniprot id: C3PFT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

548476:CAURI RS04620
gene id: 548476:CAURI_RS04620
uniprot id: C3PF69
names: Similarity
messages: Belongs to the histone deacetylase family.

548476:CAURI RS00315
gene id: 548476:CAURI_RS00315
uniprot id: C3PIX3
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11610
gene id: 548476:CAURI_RS11610
uniprot id: C3PJB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS05840
gene id: 548476:CAURI_RS05840
uniprot id: C3PFV8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

548476:CAURI RS10760
gene id: 548476:CAURI_RS10760
uniprot id: C3PIJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

548476:CAURI RS12450
gene id: 548476:CAURI_RS12450
uniprot id: C3PK73
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

548476:CAURI RS01425
gene id: 548476:CAURI_RS01425
uniprot id: C3PJX7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

548476:CAURI RS06110
gene id: 548476:CAURI_RS06110
uniprot id: C3PG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS09345
gene id: 548476:CAURI_RS09345
uniprot id: C3PHS8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

548476:CAURI RS13090
gene id: 548476:CAURI_RS13090
uniprot id: C3PKY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

548476:CAURI RS03675
gene id: 548476:CAURI_RS03675
uniprot id: C3PEN7
names: Similarity
messages: Belongs to the DEAD box helicase family.

548476:CAURI RS01100
gene id: 548476:CAURI_RS01100
uniprot id: C3PJR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS05860
gene id: 548476:CAURI_RS05860
uniprot id: C3PFW2
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06470
gene id: 548476:CAURI_RS06470
uniprot id: C3PG78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS12795
gene id: 548476:CAURI_RS12795
uniprot id: C3PKD9
names: Similarity
messages: Belongs to the UPF0371 family.

548476:CAURI RS13195
gene id: 548476:CAURI_RS13195
uniprot id: C3PL03
names: Similarity
messages: Belongs to the peptidase M1 family.

548476:CAURI RS04345
gene id: 548476:CAURI_RS04345
uniprot id: C3PF15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

548476:CAURI RS08020
gene id: 548476:CAURI_RS08020
uniprot id: C3PH22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

548476:CAURI RS00270
gene id: 548476:CAURI_RS00270
uniprot id: C3PE94
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02990
gene id: 548476:CAURI_RS02990
uniprot id: C3PEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

548476:CAURI RS11925
gene id: 548476:CAURI_RS11925
uniprot id: C3PJI3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

548476:CAURI RS06510
gene id: 548476:CAURI_RS06510
uniprot id: C3PG85
names: Similarity
messages: Belongs to the UPF0098 family.

548476:CAURI RS00585
gene id: 548476:CAURI_RS00585
uniprot id: C3PJ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

548476:CAURI RS08790
gene id: 548476:CAURI_RS08790
uniprot id: C3PHH6
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

548476:CAURI RS05270
gene id: 548476:CAURI_RS05270
uniprot id: C3PFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

548476:CAURI RS05195
gene id: 548476:CAURI_RS05195
uniprot id: C3PFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

548476:CAURI RS08510
gene id: 548476:CAURI_RS08510
uniprot id: C3PHB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

548476:CAURI RS04070
gene id: 548476:CAURI_RS04070
uniprot id: C3PEW1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

548476:CAURI RS07275
gene id: 548476:CAURI_RS07275
uniprot id: C3PGN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

548476:CAURI RS03095
gene id: 548476:CAURI_RS03095
uniprot id: C3PEC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

548476:CAURI RS07755
gene id: 548476:CAURI_RS07755
uniprot id: C3PGX0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

548476:CAURI RS04905
gene id: 548476:CAURI_RS04905
uniprot id: C3PFC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS07550
gene id: 548476:CAURI_RS07550
uniprot id: C3PGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

548476:CAURI RS02840
gene id: 548476:CAURI_RS02840
uniprot id: C3PLC4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS13165
gene id: 548476:CAURI_RS13165
uniprot id: C3PKZ8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

548476:CAURI RS13240
gene id: 548476:CAURI_RS13240
uniprot id: C3PL12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

548476:CAURI RS07990
gene id: 548476:CAURI_RS07990
uniprot id: C3PH16
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08925
gene id: 548476:CAURI_RS08925
uniprot id: C3PHK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

548476:CAURI RS02675
gene id: 548476:CAURI_RS02675
uniprot id: C3PL91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

548476:CAURI RS02455
gene id: 548476:CAURI_RS02455
uniprot id: C3PL50
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

548476:CAURI RS05240
gene id: 548476:CAURI_RS05240
uniprot id: C3PFI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

548476:CAURI RS08480
gene id: 548476:CAURI_RS08480
uniprot id: C3PHB3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

548476:CAURI RS00685
gene id: 548476:CAURI_RS00685
uniprot id: C3PJ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

548476:CAURI RS03335
gene id: 548476:CAURI_RS03335
uniprot id: C3PEH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

548476:CAURI RS05625
gene id: 548476:CAURI_RS05625
uniprot id: C3PFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

548476:CAURI RS09115
gene id: 548476:CAURI_RS09115
uniprot id: C3PHP2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

548476:CAURI RS08670
gene id: 548476:CAURI_RS08670
uniprot id: C3PHF2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

548476:CAURI RS01540
gene id: 548476:CAURI_RS01540
uniprot id: C3PK02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

548476:CAURI RS02385
gene id: 548476:CAURI_RS02385
uniprot id: C3PL36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

548476:CAURI RS02025
gene id: 548476:CAURI_RS02025
uniprot id: C3PKN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

548476:CAURI RS02070
gene id: 548476:CAURI_RS02070
uniprot id: C3PKP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

548476:CAURI RS00835
gene id: 548476:CAURI_RS00835
uniprot id: C3PJ77
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS01695
gene id: 548476:CAURI_RS01695
uniprot id: C3PKG9
names: Similarity
messages: Belongs to the YoeB family.

548476:CAURI RS00880
gene id: 548476:CAURI_RS00880
uniprot id: C3PJ87
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07150
gene id: 548476:CAURI_RS07150
uniprot id: C3PGK6
names: Similarity
messages: Belongs to the universal stress protein A family.

548476:CAURI RS06680
gene id: 548476:CAURI_RS06680
uniprot id: C3PGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS01700
gene id: 548476:CAURI_RS01700
uniprot id: C3PKH0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

548476:CAURI RS05335
gene id: 548476:CAURI_RS05335
uniprot id: C3PFK9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04700
gene id: 548476:CAURI_RS04700
uniprot id: C3PF85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

548476:CAURI RS06200
gene id: 548476:CAURI_RS06200
uniprot id: C3PG25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS05695
gene id: 548476:CAURI_RS05695
uniprot id: C3PFS9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

548476:CAURI RS07175
gene id: 548476:CAURI_RS07175
uniprot id: C3PGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

548476:CAURI RS09545
gene id: 548476:CAURI_RS09545
uniprot id: C3PHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS06565
gene id: 548476:CAURI_RS06565
uniprot id: C3PG96
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

548476:CAURI RS04940
gene id: 548476:CAURI_RS04940
uniprot id: C3PFC8
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07850
gene id: 548476:CAURI_RS07850
uniprot id: C3PGY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

548476:CAURI RS10790
gene id: 548476:CAURI_RS10790
uniprot id: C3PIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS13210
gene id: 548476:CAURI_RS13210
uniprot id: C3PL06
names: Similarity
messages: Belongs to the thioredoxin family.

548476:CAURI RS08185
gene id: 548476:CAURI_RS08185
uniprot id: C3PH55
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

548476:CAURI RS02885
gene id: 548476:CAURI_RS02885
uniprot id: C3PLD2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

548476:CAURI RS09365
gene id: 548476:CAURI_RS09365
uniprot id: C3PHT2
names: Similarity
messages: Belongs to the barstar family.

548476:CAURI RS05670
gene id: 548476:CAURI_RS05670
uniprot id: C3PFS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

548476:CAURI RS08290
gene id: 548476:CAURI_RS08290
uniprot id: C3PH76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

548476:CAURI RS04085
gene id: 548476:CAURI_RS04085
uniprot id: C3PEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

548476:CAURI RS09655
gene id: 548476:CAURI_RS09655
uniprot id: C3PHY9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS10975
gene id: 548476:CAURI_RS10975
uniprot id: C3PIN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

548476:CAURI RS01955
gene id: 548476:CAURI_RS01955
uniprot id: C3PKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

548476:CAURI RS11080
gene id: 548476:CAURI_RS11080
uniprot id: C3PIQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

548476:CAURI RS02520
gene id: 548476:CAURI_RS02520
uniprot id: C3PL61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

548476:CAURI RS10785
gene id: 548476:CAURI_RS10785
uniprot id: C3PIJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

548476:CAURI RS02340
gene id: 548476:CAURI_RS02340
uniprot id: C3PL28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

548476:CAURI RS03635
gene id: 548476:CAURI_RS03635
uniprot id: C3PEM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

548476:CAURI RS03595
gene id: 548476:CAURI_RS03595
uniprot id: C3PEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

548476:CAURI RS07055
gene id: 548476:CAURI_RS07055
uniprot id: C3PGI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

548476:CAURI RS00540
gene id: 548476:CAURI_RS00540
uniprot id: C3PJ21
names: Similarity
messages: Belongs to the LOG family.

548476:CAURI RS02795
gene id: 548476:CAURI_RS02795
uniprot id: C3PLB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

548476:CAURI RS12820
gene id: 548476:CAURI_RS12820
uniprot id: C3PKE3
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02380
gene id: 548476:CAURI_RS02380
uniprot id: C3PL35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

548476:CAURI RS09980
gene id: 548476:CAURI_RS09980
uniprot id: C3PI52
names: Similarity
messages: Belongs to the peptidase C40 family.

548476:CAURI RS07290
gene id: 548476:CAURI_RS07290
uniprot id: C3PGN3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

548476:CAURI RS11930
gene id: 548476:CAURI_RS11930
uniprot id: C3PJI4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07715
gene id: 548476:CAURI_RS07715
uniprot id: C3PGW1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

548476:CAURI RS00680
gene id: 548476:CAURI_RS00680
uniprot id: C3PJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

548476:CAURI RS12655
gene id: 548476:CAURI_RS12655
uniprot id: C3PKB4
names: Similarity
messages: Belongs to the universal stress protein A family.

548476:CAURI RS09455
gene id: 548476:CAURI_RS09455
uniprot id: C3PHU9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

548476:CAURI RS00770
gene id: 548476:CAURI_RS00770
uniprot id: C3PJ65
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.

548476:CAURI RS04705
gene id: 548476:CAURI_RS04705
uniprot id: C3PF86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

548476:CAURI RS08675
gene id: 548476:CAURI_RS08675
uniprot id: C3PHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

548476:CAURI RS04230
gene id: 548476:CAURI_RS04230
uniprot id: C3PEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

548476:CAURI RS02735
gene id: 548476:CAURI_RS02735
uniprot id: C3PLA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

548476:CAURI RS00890
gene id: 548476:CAURI_RS00890
uniprot id: C3PJ89
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

548476:CAURI RS01060
gene id: 548476:CAURI_RS01060
uniprot id: C3PJQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

548476:CAURI RS01240
gene id: 548476:CAURI_RS01240
uniprot id: C3PJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS00755
gene id: 548476:CAURI_RS00755
uniprot id: C3PJ61
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-68 and Arg-71) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

548476:CAURI RS08375
gene id: 548476:CAURI_RS08375
uniprot id: C3PH92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

548476:CAURI RS00340
gene id: 548476:CAURI_RS00340
uniprot id: C3PIX7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

548476:CAURI RS08425
gene id: 548476:CAURI_RS08425
uniprot id: C3PHA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

548476:CAURI RS03695
gene id: 548476:CAURI_RS03695
uniprot id: C3PEP1
names: Caution
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS08395
gene id: 548476:CAURI_RS08395
uniprot id: C3PH96
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

548476:CAURI RS12560
gene id: 548476:CAURI_RS12560
uniprot id: C3PK95
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

548476:CAURI RS08365
gene id: 548476:CAURI_RS08365
uniprot id: C3PH90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS08275
gene id: 548476:CAURI_RS08275
uniprot id: C3PH73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

548476:CAURI RS04280
gene id: 548476:CAURI_RS04280
uniprot id: C3PF02
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS01900
gene id: 548476:CAURI_RS01900
uniprot id: C3PKL1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

548476:CAURI RS08445
gene id: 548476:CAURI_RS08445
uniprot id: C3PHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

548476:CAURI RS07375
gene id: 548476:CAURI_RS07375
uniprot id: C3PGQ0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

548476:CAURI RS13040
gene id: 548476:CAURI_RS13040
uniprot id: C3PKX4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS05205
gene id: 548476:CAURI_RS05205
uniprot id: C3PFI1
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04645
gene id: 548476:CAURI_RS04645
uniprot id: C3PF74
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08220
gene id: 548476:CAURI_RS08220
uniprot id: C3PH62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

548476:CAURI RS03130
gene id: 548476:CAURI_RS03130
uniprot id: C3PED1
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

548476:CAURI RS13020
gene id: 548476:CAURI_RS13020
uniprot id: C3PKX0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS11795
gene id: 548476:CAURI_RS11795
uniprot id: C3PJF6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04900
gene id: 548476:CAURI_RS04900
uniprot id: C3PFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

548476:CAURI RS08335
gene id: 548476:CAURI_RS08335
uniprot id: C3PH84
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05630
gene id: 548476:CAURI_RS05630
uniprot id: C3PFR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

548476:CAURI RS02120
gene id: 548476:CAURI_RS02120
uniprot id: C3PKQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

548476:CAURI RS04785
gene id: 548476:CAURI_RS04785
uniprot id: C3PFA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

548476:CAURI RS09085
gene id: 548476:CAURI_RS09085
uniprot id: C3PHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

548476:CAURI RS12350
gene id: 548476:CAURI_RS12350
uniprot id: C3PK52
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS00645
gene id: 548476:CAURI_RS00645
uniprot id: C3PJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS05605
gene id: 548476:CAURI_RS05605
uniprot id: C3PFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

548476:CAURI RS05960
gene id: 548476:CAURI_RS05960
uniprot id: C3PFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS12010
gene id: 548476:CAURI_RS12010
uniprot id: C3PJK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

548476:CAURI RS06360
gene id: 548476:CAURI_RS06360
uniprot id: C3PG57
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

548476:CAURI RS11605
gene id: 548476:CAURI_RS11605
uniprot id: C3PJB7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

548476:CAURI RS02285
gene id: 548476:CAURI_RS02285
uniprot id: C3PL17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

548476:CAURI RS01750
gene id: 548476:CAURI_RS01750
uniprot id: C3PKI0
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS03515
gene id: 548476:CAURI_RS03515
uniprot id: C3PEK6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

548476:CAURI RS00635
gene id: 548476:CAURI_RS00635
uniprot id: C3PJ39
names: Similarity
messages: Belongs to the peptidase M13 family.

548476:CAURI RS08730
gene id: 548476:CAURI_RS08730
uniprot id: C3PHG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

548476:CAURI RS01190
gene id: 548476:CAURI_RS01190
uniprot id: C3PJT0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

548476:CAURI RS02155
gene id: 548476:CAURI_RS02155
uniprot id: C3PKQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

548476:CAURI RS02255
gene id: 548476:CAURI_RS02255
uniprot id: C3PKS9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

548476:CAURI RS04490
gene id: 548476:CAURI_RS04490
uniprot id: C3PF44
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

548476:CAURI RS03630
gene id: 548476:CAURI_RS03630
uniprot id: C3PEM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

548476:CAURI RS07485
gene id: 548476:CAURI_RS07485
uniprot id: C3PGS2
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

548476:CAURI RS02140
gene id: 548476:CAURI_RS02140
uniprot id: C3PKQ6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

548476:CAURI RS01590
gene id: 548476:CAURI_RS01590
uniprot id: C3PK12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

548476:CAURI RS08160
gene id: 548476:CAURI_RS08160
uniprot id: C3PH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

548476:CAURI RS05635
gene id: 548476:CAURI_RS05635
uniprot id: C3PFR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

548476:CAURI RS00885
gene id: 548476:CAURI_RS00885
uniprot id: C3PJ88
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02210
gene id: 548476:CAURI_RS02210
uniprot id: C3PKS0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

548476:CAURI RS01390
gene id: 548476:CAURI_RS01390
uniprot id: C3PJX0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

548476:CAURI RS09615
gene id: 548476:CAURI_RS09615
uniprot id: C3PHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

548476:CAURI RS07095
gene id: 548476:CAURI_RS07095
uniprot id: C3PGJ5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

548476:CAURI RS10340
gene id: 548476:CAURI_RS10340
uniprot id: C3PIB5
names: Similarity
messages: Belongs to the peptidase C40 family.

548476:CAURI RS10915
gene id: 548476:CAURI_RS10915
uniprot id: C3PIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS08070
gene id: 548476:CAURI_RS08070
uniprot id: C3PH32
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

548476:CAURI RS03525
gene id: 548476:CAURI_RS03525
uniprot id: C3PEK8
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

548476:CAURI RS13035
gene id: 548476:CAURI_RS13035
uniprot id: C3PKX3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

548476:CAURI RS07235
gene id: 548476:CAURI_RS07235
uniprot id: C3PGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

548476:CAURI RS09495
gene id: 548476:CAURI_RS09495
uniprot id: C3PHV7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

548476:CAURI RS07700
gene id: 548476:CAURI_RS07700
uniprot id: C3PGV8
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07105
gene id: 548476:CAURI_RS07105
uniprot id: C3PGJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

548476:CAURI RS07280
gene id: 548476:CAURI_RS07280
uniprot id: C3PGN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

548476:CAURI RS04190
gene id: 548476:CAURI_RS04190
uniprot id: C3PEY4
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

548476:CAURI RS13100
gene id: 548476:CAURI_RS13100
uniprot id: C3PKY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

548476:CAURI RS08700
gene id: 548476:CAURI_RS08700
uniprot id: C3PHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

548476:CAURI RS07595
gene id: 548476:CAURI_RS07595
uniprot id: C3PGT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

548476:CAURI RS01820
gene id: 548476:CAURI_RS01820
uniprot id: C3PKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS09010
gene id: 548476:CAURI_RS09010
uniprot id: C3PHM1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

548476:CAURI RS00080
gene id: 548476:CAURI_RS00080
uniprot id: B3GW58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

548476:CAURI RS02550
gene id: 548476:CAURI_RS02550
uniprot id: C3PL67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

548476:CAURI RS13235
gene id: 548476:CAURI_RS13235
uniprot id: C3PL11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

548476:CAURI RS12550
gene id: 548476:CAURI_RS12550
uniprot id: C3PK93
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

548476:CAURI RS03750
gene id: 548476:CAURI_RS03750
uniprot id: C3PEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

548476:CAURI RS02240
gene id: 548476:CAURI_RS02240
uniprot id: C3PKS6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06950
gene id: 548476:CAURI_RS06950
uniprot id: C3PGH2
names: Similarity
messages: Belongs to the TlyA family.

548476:CAURI RS09415
gene id: 548476:CAURI_RS09415
uniprot id: C3PHU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

548476:CAURI RS09815
gene id: 548476:CAURI_RS09815
uniprot id: C3PI20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

548476:CAURI RS02130
gene id: 548476:CAURI_RS02130
uniprot id: C3PKQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

548476:CAURI RS02685
gene id: 548476:CAURI_RS02685
uniprot id: C3PL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

548476:CAURI RS02335
gene id: 548476:CAURI_RS02335
uniprot id: C3PL27
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

548476:CAURI RS06880
gene id: 548476:CAURI_RS06880
uniprot id: C3PGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

548476:CAURI RS04610
gene id: 548476:CAURI_RS04610
uniprot id: C3PF67
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

548476:CAURI RS05215
gene id: 548476:CAURI_RS05215
uniprot id: C3PFI3
names: Similarity
messages: Belongs to the LOG family.

548476:CAURI RS04875
gene id: 548476:CAURI_RS04875
uniprot id: C3PFB6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

548476:CAURI RS10780
gene id: 548476:CAURI_RS10780
uniprot id: C3PIJ5
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04210
gene id: 548476:CAURI_RS04210
uniprot id: C3PEY8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

548476:CAURI RS12720
gene id: 548476:CAURI_RS12720
uniprot id: C3PKC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

548476:CAURI RS11695
gene id: 548476:CAURI_RS11695
uniprot id: C3PJD6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06465
gene id: 548476:CAURI_RS06465
uniprot id: C3PG77
names: Similarity
messages: Belongs to the peptidase C40 family.

548476:CAURI RS03600
gene id: 548476:CAURI_RS03600
uniprot id: C3PEM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

548476:CAURI RS00255
gene id: 548476:CAURI_RS00255
uniprot id: C3PE91
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

548476:CAURI RS03350
gene id: 548476:CAURI_RS03350
uniprot id: C3PEH3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

548476:CAURI RS03320
gene id: 548476:CAURI_RS03320
uniprot id: C3PEG7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07690
gene id: 548476:CAURI_RS07690
uniprot id: C3PGV6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04060
gene id: 548476:CAURI_RS04060
uniprot id: C3PEV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS09840
gene id: 548476:CAURI_RS09840
uniprot id: C3PI25
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

548476:CAURI RS13000
gene id: 548476:CAURI_RS13000
uniprot id: C3PKW6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS08055
gene id: 548476:CAURI_RS08055
uniprot id: C3PH29
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

548476:CAURI RS06695
gene id: 548476:CAURI_RS06695
uniprot id: C3PGC2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS08950
gene id: 548476:CAURI_RS08950
uniprot id: C3PHK9
names: Similarity
messages: Belongs to the glutamine synthetase family.

548476:CAURI RS01285
gene id: 548476:CAURI_RS01285
uniprot id: C3PJV0
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08945
gene id: 548476:CAURI_RS08945
uniprot id: C3PHK8
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08860
gene id: 548476:CAURI_RS08860
uniprot id: C3PHJ1
names: Similarity
messages: Belongs to the asparagine synthetase family.

548476:CAURI RS05650
gene id: 548476:CAURI_RS05650
uniprot id: C3PFS0
names: Similarity
messages: Belongs to the UPF0045 family.

548476:CAURI RS02405
gene id: 548476:CAURI_RS02405
uniprot id: C3PL40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS05560
gene id: 548476:CAURI_RS05560
uniprot id: C3PFQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

548476:CAURI RS09540
gene id: 548476:CAURI_RS09540
uniprot id: C3PHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS06220
gene id: 548476:CAURI_RS06220
uniprot id: C3PG29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

548476:CAURI RS06585
gene id: 548476:CAURI_RS06585
uniprot id: C3PGA0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

548476:CAURI RS11160
gene id: 548476:CAURI_RS11160
uniprot id: C3PIR8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

548476:CAURI RS07930
gene id: 548476:CAURI_RS07930
uniprot id: C3PH05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

548476:CAURI RS08115
gene id: 548476:CAURI_RS08115
uniprot id: C3PH41
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS13070
gene id: 548476:CAURI_RS13070
uniprot id: C3PKY0
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11395
gene id: 548476:CAURI_RS11395
uniprot id: C3PIV8
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

548476:CAURI RS11375
gene id: 548476:CAURI_RS11375
uniprot id: C3PIV4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

548476:CAURI RS06580
gene id: 548476:CAURI_RS06580
uniprot id: C3PG99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

548476:CAURI RS08300
gene id: 548476:CAURI_RS08300
uniprot id: C3PH78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

548476:CAURI RS01365
gene id: 548476:CAURI_RS01365
uniprot id: C3PJW5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

548476:CAURI RS09750
gene id: 548476:CAURI_RS09750
uniprot id: C3PI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS05310
gene id: 548476:CAURI_RS05310
uniprot id: C3PFK4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

548476:CAURI RS05975
gene id: 548476:CAURI_RS05975
uniprot id: C3PFY3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

548476:CAURI RS05145
gene id: 548476:CAURI_RS05145
uniprot id: C3PFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS01430
gene id: 548476:CAURI_RS01430
uniprot id: C3PJX8
names: Similarity
messages: Belongs to the peptidase M1 family.

548476:CAURI RS04195
gene id: 548476:CAURI_RS04195
uniprot id: C3PEY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS11750
gene id: 548476:CAURI_RS11750
uniprot id: C3PJE7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

548476:CAURI RS06490
gene id: 548476:CAURI_RS06490
uniprot id: C3PG82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS03030
gene id: 548476:CAURI_RS03030
uniprot id: C3PEB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS02300
gene id: 548476:CAURI_RS02300
uniprot id: C3PL20
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS01320
gene id: 548476:CAURI_RS01320
uniprot id: C3PJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS02360
gene id: 548476:CAURI_RS02360
uniprot id: C3PL31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS12355
gene id: 548476:CAURI_RS12355
uniprot id: C3PK53
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05520
gene id: 548476:CAURI_RS05520
uniprot id: C3PFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS09030
gene id: 548476:CAURI_RS09030
uniprot id: C3PHM6
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

548476:CAURI RS11010
gene id: 548476:CAURI_RS11010
uniprot id: C3PIN9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02600
gene id: 548476:CAURI_RS02600
uniprot id: C3PL77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

548476:CAURI RS07255
gene id: 548476:CAURI_RS07255
uniprot id: C3PGM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS00950
gene id: 548476:CAURI_RS00950
uniprot id: C3PJN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS07135
gene id: 548476:CAURI_RS07135
uniprot id: C3PGK3
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05125
gene id: 548476:CAURI_RS05125
uniprot id: C3PFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.

548476:CAURI RS01950
gene id: 548476:CAURI_RS01950
uniprot id: C3PKL7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

548476:CAURI RS05830
gene id: 548476:CAURI_RS05830
uniprot id: C3PFV6
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

548476:CAURI RS10750
gene id: 548476:CAURI_RS10750
uniprot id: C3PIJ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

548476:CAURI RS02400
gene id: 548476:CAURI_RS02400
uniprot id: C3PL39
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

548476:CAURI RS13050
gene id: 548476:CAURI_RS13050
uniprot id: C3PKX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

548476:CAURI RS06895
gene id: 548476:CAURI_RS06895
uniprot id: C3PGG1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

548476:CAURI RS12205
gene id: 548476:CAURI_RS12205
uniprot id: C3PK25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS08615
gene id: 548476:CAURI_RS08615
uniprot id: C3PHE1
names: Similarity
messages: Belongs to the asparaginase 1 family.

548476:CAURI RS11780
gene id: 548476:CAURI_RS11780
uniprot id: C3PJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

548476:CAURI RS01850
gene id: 548476:CAURI_RS01850
uniprot id: C3PKK1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS11325
gene id: 548476:CAURI_RS11325
uniprot id: C3PIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

548476:CAURI RS03275
gene id: 548476:CAURI_RS03275
uniprot id: C3PEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS11340
gene id: 548476:CAURI_RS11340
uniprot id: C3PIU7
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

548476:CAURI RS11745
gene id: 548476:CAURI_RS11745
uniprot id: C3PJE6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

548476:CAURI RS07955
gene id: 548476:CAURI_RS07955
uniprot id: C3PH09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

548476:CAURI RS02160
gene id: 548476:CAURI_RS02160
uniprot id: C3PKR0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

548476:CAURI RS07065
gene id: 548476:CAURI_RS07065
uniprot id: C3PGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

548476:CAURI RS02005
gene id: 548476:CAURI_RS02005
uniprot id: C3PKM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

548476:CAURI RS02065
gene id: 548476:CAURI_RS02065
uniprot id: C3PKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

548476:CAURI RS05105
gene id: 548476:CAURI_RS05105
uniprot id: C3PFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

548476:CAURI RS04970
gene id: 548476:CAURI_RS04970
uniprot id: C3PFD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

548476:CAURI RS04340
gene id: 548476:CAURI_RS04340
uniprot id: C3PF14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

548476:CAURI RS06250
gene id: 548476:CAURI_RS06250
uniprot id: C3PG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

548476:CAURI RS08005
gene id: 548476:CAURI_RS08005
uniprot id: C3PH19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

548476:CAURI RS09790
gene id: 548476:CAURI_RS09790
uniprot id: C3PI15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

548476:CAURI RS02865
gene id: 548476:CAURI_RS02865
uniprot id: C3PLC8
names: Similarity
messages: Belongs to the peptidase C40 family.

548476:CAURI RS11075
gene id: 548476:CAURI_RS11075
uniprot id: C3PIQ2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

548476:CAURI RS04590
gene id: 548476:CAURI_RS04590
uniprot id: C3PF63
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

548476:CAURI RS06595
gene id: 548476:CAURI_RS06595
uniprot id: C3PGA2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

548476:CAURI RS10955
gene id: 548476:CAURI_RS10955
uniprot id: C3PIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

548476:CAURI RS07405
gene id: 548476:CAURI_RS07405
uniprot id: C3PGQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

548476:CAURI RS04795
gene id: 548476:CAURI_RS04795
uniprot id: C3PFA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

548476:CAURI RS03570
gene id: 548476:CAURI_RS03570
uniprot id: C3PEL6
names: Similarity
messages: Belongs to the thymidylate kinase family.

548476:CAURI RS06095
gene id: 548476:CAURI_RS06095
uniprot id: C3PG04
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

548476:CAURI RS02110
gene id: 548476:CAURI_RS02110
uniprot id: C3PKQ0
names: Similarity
messages: Belongs to the asp23 family.

548476:CAURI RS04330
gene id: 548476:CAURI_RS04330
uniprot id: C3PF12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

548476:CAURI RS05645
gene id: 548476:CAURI_RS05645
uniprot id: C3PFR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

548476:CAURI RS03025
gene id: 548476:CAURI_RS03025
uniprot id: C3PEB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS03475
gene id: 548476:CAURI_RS03475
uniprot id: C3PEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS07250
gene id: 548476:CAURI_RS07250
uniprot id: C3PGM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS06275
gene id: 548476:CAURI_RS06275
uniprot id: C3PG40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS12585
gene id: 548476:CAURI_RS12585
uniprot id: C3PKA0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

548476:CAURI RS01825
gene id: 548476:CAURI_RS01825
uniprot id: C3PKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS02680
gene id: 548476:CAURI_RS02680
uniprot id: C3PL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

548476:CAURI RS02395
gene id: 548476:CAURI_RS02395
uniprot id: C3PL38
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

548476:CAURI RS05090
gene id: 548476:CAURI_RS05090
uniprot id: C3PFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

548476:CAURI RS00295
gene id: 548476:CAURI_RS00295
uniprot id: C3PE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

548476:CAURI RS11445
gene id: 548476:CAURI_RS11445
uniprot id: C3PIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

548476:CAURI RS05780
gene id: 548476:CAURI_RS05780
uniprot id: C3PFU5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

548476:CAURI RS13250
gene id: 548476:CAURI_RS13250
uniprot id: C3PL13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

548476:CAURI RS04955
gene id: 548476:CAURI_RS04955
uniprot id: C3PFD1
names: Similarity
messages: Belongs to the FBPase class 2 family.

548476:CAURI RS02165
gene id: 548476:CAURI_RS02165
uniprot id: C3PKR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

548476:CAURI RS08035
gene id: 548476:CAURI_RS08035
uniprot id: C3PH25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS04570
gene id: 548476:CAURI_RS04570
uniprot id: C3PF59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS11765
gene id: 548476:CAURI_RS11765
uniprot id: C3PJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

548476:CAURI RS03640
gene id: 548476:CAURI_RS03640
uniprot id: C3PEN0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

548476:CAURI RS11870
gene id: 548476:CAURI_RS11870
uniprot id: C3PJH2
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04950
gene id: 548476:CAURI_RS04950
uniprot id: C3PFD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

548476:CAURI RS13365
gene id: 548476:CAURI_RS13365
uniprot id: C3PJS6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

548476:CAURI RS06560
gene id: 548476:CAURI_RS06560
uniprot id: C3PG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

548476:CAURI RS01545
gene id: 548476:CAURI_RS01545
uniprot id: C3PK03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

548476:CAURI RS08360
gene id: 548476:CAURI_RS08360
uniprot id: C3PH89
names: Similarity
messages: Belongs to the acylphosphatase family.

548476:CAURI RS05910
gene id: 548476:CAURI_RS05910
uniprot id: C3PFX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

548476:CAURI RS06170
gene id: 548476:CAURI_RS06170
uniprot id: C3PG19
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

548476:CAURI RS12045
gene id: 548476:CAURI_RS12045
uniprot id: C3PJK7
names: Similarity
messages: Belongs to the class-I fumarase family.

548476:CAURI RS04665
gene id: 548476:CAURI_RS04665
uniprot id: C3PF78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

548476:CAURI RS00650
gene id: 548476:CAURI_RS00650
uniprot id: C3PJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS03000
gene id: 548476:CAURI_RS03000
uniprot id: C3PEA5
names: Similarity
messages: Belongs to the AccD/PCCB family.

548476:CAURI RS03645
gene id: 548476:CAURI_RS03645
uniprot id: C3PEN1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

548476:CAURI RS12565
gene id: 548476:CAURI_RS12565
uniprot id: C3PK96
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

548476:CAURI RS07960
gene id: 548476:CAURI_RS07960
uniprot id: C3PH10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

548476:CAURI RS11660
gene id: 548476:CAURI_RS11660
uniprot id: C3PJC9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

548476:CAURI RS03880
gene id: 548476:CAURI_RS03880
uniprot id: C3PES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

548476:CAURI RS11140
gene id: 548476:CAURI_RS11140
uniprot id: C3PIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

548476:CAURI RS03540
gene id: 548476:CAURI_RS03540
uniprot id: C3PEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS06255
gene id: 548476:CAURI_RS06255
uniprot id: C3PG36
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

548476:CAURI RS09855
gene id: 548476:CAURI_RS09855
uniprot id: C3PI28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

548476:CAURI RS11815
gene id: 548476:CAURI_RS11815
uniprot id: C3PJG0
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

548476:CAURI RS11045
gene id: 548476:CAURI_RS11045
uniprot id: C3PIP6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

548476:CAURI RS01245
gene id: 548476:CAURI_RS01245
uniprot id: C3PJU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS01290
gene id: 548476:CAURI_RS01290
uniprot id: C3PJV1
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS01025
gene id: 548476:CAURI_RS01025
uniprot id: C3PG84
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

548476:CAURI RS01770
gene id: 548476:CAURI_RS01770
uniprot id: C3PKI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS00140
gene id: 548476:CAURI_RS00140
uniprot id: C3PE72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

548476:CAURI RS07830
gene id: 548476:CAURI_RS07830
uniprot id: C3PGY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

548476:CAURI RS06550
gene id: 548476:CAURI_RS06550
uniprot id: C3PG93
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

548476:CAURI RS02290
gene id: 548476:CAURI_RS02290
uniprot id: C3PL18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

548476:CAURI RS06530
gene id: 548476:CAURI_RS06530
uniprot id: C3PG89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

548476:CAURI RS12790
gene id: 548476:CAURI_RS12790
uniprot id: C3PKD8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

548476:CAURI RS05925
gene id: 548476:CAURI_RS05925
uniprot id: C3PFX4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

548476:CAURI RS08370
gene id: 548476:CAURI_RS08370
uniprot id: C3PH91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

548476:CAURI RS03215
gene id: 548476:CAURI_RS03215
uniprot id: C3PEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

548476:CAURI RS03660
gene id: 548476:CAURI_RS03660
uniprot id: C3PEN4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

548476:CAURI RS08455
gene id: 548476:CAURI_RS08455
uniprot id: C3PHA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS02585
gene id: 548476:CAURI_RS02585
uniprot id: C3PL74
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

548476:CAURI RS07430
gene id: 548476:CAURI_RS07430
uniprot id: C3PGR1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

548476:CAURI RS05890
gene id: 548476:CAURI_RS05890
uniprot id: C3PFW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

548476:CAURI RS09730
gene id: 548476:CAURI_RS09730
uniprot id: C3PI04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

548476:CAURI RS08850
gene id: 548476:CAURI_RS08850
uniprot id: C3PHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

548476:CAURI RS12705
gene id: 548476:CAURI_RS12705
uniprot id: C3PKC1
names: Similarity
messages: Belongs to the PspA/IM30 family.

548476:CAURI RS09135
gene id: 548476:CAURI_RS09135
uniprot id: C3PHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

548476:CAURI RS11245
gene id: 548476:CAURI_RS11245
uniprot id: C3PIT3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

548476:CAURI RS07265
gene id: 548476:CAURI_RS07265
uniprot id: C3PGM8
names: Similarity
messages: Belongs to the peptidase A24 family.

548476:CAURI RS02415
gene id: 548476:CAURI_RS02415
uniprot id: C3PL42
names: Similarity
messages: Belongs to the peptidase S8 family.

548476:CAURI RS02805
gene id: 548476:CAURI_RS02805
uniprot id: C3PLB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

548476:CAURI RS05260
gene id: 548476:CAURI_RS05260
uniprot id: C3PFJ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

548476:CAURI RS11545
gene id: 548476:CAURI_RS11545
uniprot id: C3PJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

548476:CAURI RS11680
gene id: 548476:CAURI_RS11680
uniprot id: C3PJD3
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08060
gene id: 548476:CAURI_RS08060
uniprot id: C3PH30
names: Similarity
messages: Belongs to the MQO family.

548476:CAURI RS09675
gene id: 548476:CAURI_RS09675
uniprot id: C3PHZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

548476:CAURI RS01640
gene id: 548476:CAURI_RS01640
uniprot id: C3PKF8
names: Similarity
messages: Belongs to the LOR family.

548476:CAURI RS01445
gene id: 548476:CAURI_RS01445
uniprot id: C3PJY2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

548476:CAURI RS12130
gene id: 548476:CAURI_RS12130
uniprot id: C3PJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

548476:CAURI RS09475
gene id: 548476:CAURI_RS09475
uniprot id: C3PHV3
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS01450
gene id: 548476:CAURI_RS01450
uniprot id: C3PJY4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

548476:CAURI RS11135
gene id: 548476:CAURI_RS11135
uniprot id: C3PIR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

548476:CAURI RS06270
gene id: 548476:CAURI_RS06270
uniprot id: C3PG39
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

548476:CAURI RS02590
gene id: 548476:CAURI_RS02590
uniprot id: C3PL75
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

548476:CAURI RS02715
gene id: 548476:CAURI_RS02715
uniprot id: C3PL99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

548476:CAURI RS03860
gene id: 548476:CAURI_RS03860
uniprot id: C3PES2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

548476:CAURI RS11840
gene id: 548476:CAURI_RS11840
uniprot id: C3PJG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

548476:CAURI RS06165
gene id: 548476:CAURI_RS06165
uniprot id: C3PG18
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS03555
gene id: 548476:CAURI_RS03555
uniprot id: C3PEL3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

548476:CAURI RS04485
gene id: 548476:CAURI_RS04485
uniprot id: C3PF43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

548476:CAURI RS09035
gene id: 548476:CAURI_RS09035
uniprot id: C3PHM7
names: Similarity
messages: Belongs to the glutamine synthetase family.

548476:CAURI RS04445
gene id: 548476:CAURI_RS04445
uniprot id: C3PF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

548476:CAURI RS05570
gene id: 548476:CAURI_RS05570
uniprot id: C3PFQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS04505
gene id: 548476:CAURI_RS04505
uniprot id: C3PF47
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07920
gene id: 548476:CAURI_RS07920
uniprot id: C3PH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

548476:CAURI RS11120
gene id: 548476:CAURI_RS11120
uniprot id: C3PIQ9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07050
gene id: 548476:CAURI_RS07050
uniprot id: C3PGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

548476:CAURI RS02650
gene id: 548476:CAURI_RS02650
uniprot id: C3PL86
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

548476:CAURI RS05180
gene id: 548476:CAURI_RS05180
uniprot id: C3PFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

548476:CAURI RS03960
gene id: 548476:CAURI_RS03960
uniprot id: C3PEU1
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05490
gene id: 548476:CAURI_RS05490
uniprot id: C3PFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

548476:CAURI RS03060
gene id: 548476:CAURI_RS03060
uniprot id: C3PEB7
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

548476:CAURI RS05930
gene id: 548476:CAURI_RS05930
uniprot id: C3PFX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS09630
gene id: 548476:CAURI_RS09630
uniprot id: C3PHY4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

548476:CAURI RS05040
gene id: 548476:CAURI_RS05040
uniprot id: C3PFE8
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11360
gene id: 548476:CAURI_RS11360
uniprot id: C3PIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

548476:CAURI RS11650
gene id: 548476:CAURI_RS11650
uniprot id: C3PJC6
names: Similarity
messages: Belongs to the Nth/MutY family.

548476:CAURI RS05735
gene id: 548476:CAURI_RS05735
uniprot id: C3PFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

548476:CAURI RS12590
gene id: 548476:CAURI_RS12590
uniprot id: C3PKA1
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07765
gene id: 548476:CAURI_RS07765
uniprot id: C3PGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

548476:CAURI RS11950
gene id: 548476:CAURI_RS11950
uniprot id: C3PJI8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

548476:CAURI RS03455
gene id: 548476:CAURI_RS03455
uniprot id: C3PEJ4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02190
gene id: 548476:CAURI_RS02190
uniprot id: C3PKR6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06065
gene id: 548476:CAURI_RS06065
uniprot id: C3PFZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

548476:CAURI RS03545
gene id: 548476:CAURI_RS03545
uniprot id: C3PEL1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

548476:CAURI RS02355
gene id: 548476:CAURI_RS02355
uniprot id: C3PL30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

548476:CAURI RS09720
gene id: 548476:CAURI_RS09720
uniprot id: C3PI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

548476:CAURI RS08835
gene id: 548476:CAURI_RS08835
uniprot id: C3PHI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

548476:CAURI RS13095
gene id: 548476:CAURI_RS13095
uniprot id: C3PKY5
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

548476:CAURI RS02605
gene id: 548476:CAURI_RS02605
uniprot id: C3PL78
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

548476:CAURI RS09700
gene id: 548476:CAURI_RS09700
uniprot id: C3PHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

548476:CAURI RS13200
gene id: 548476:CAURI_RS13200
uniprot id: C3PL04
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

548476:CAURI RS07710
gene id: 548476:CAURI_RS07710
uniprot id: C3PGW0
names: Subcellular Location Annotation
messages: Cytoplasm

548476:CAURI RS06265
gene id: 548476:CAURI_RS06265
uniprot id: C3PG38
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

548476:CAURI RS02185
gene id: 548476:CAURI_RS02185
uniprot id: C3PKR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

548476:CAURI RS08740
gene id: 548476:CAURI_RS08740
uniprot id: C3PHG6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02875
gene id: 548476:CAURI_RS02875
uniprot id: C3PLD0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

548476:CAURI RS11315
gene id: 548476:CAURI_RS11315
uniprot id: C3PIU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

548476:CAURI RS02905
gene id: 548476:CAURI_RS02905
uniprot id: C3PLD6
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

548476:CAURI RS05580
gene id: 548476:CAURI_RS05580
uniprot id: C3PFQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

548476:CAURI RS09625
gene id: 548476:CAURI_RS09625
uniprot id: C3PHY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

548476:CAURI RS12135
gene id: 548476:CAURI_RS12135
uniprot id: C3PJM6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

548476:CAURI RS11515
gene id: 548476:CAURI_RS11515
uniprot id: C3PJA0
names: Similarity
messages: Belongs to the TPP enzyme family.

548476:CAURI RS10840
gene id: 548476:CAURI_RS10840
uniprot id: C3PIK6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

548476:CAURI RS07660
gene id: 548476:CAURI_RS07660
uniprot id: C3PGV0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

548476:CAURI RS08340
gene id: 548476:CAURI_RS08340
uniprot id: C3PH85
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07840
gene id: 548476:CAURI_RS07840
uniprot id: C3PGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS05900
gene id: 548476:CAURI_RS05900
uniprot id: C3PFW9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

548476:CAURI RS00805
gene id: 548476:CAURI_RS00805
uniprot id: C3PJ72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

548476:CAURI RS05575
gene id: 548476:CAURI_RS05575
uniprot id: C3PFQ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

548476:CAURI RS03410
gene id: 548476:CAURI_RS03410
uniprot id: C3PEI5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

548476:CAURI RS04165
gene id: 548476:CAURI_RS04165
uniprot id: C3PEY0
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05025
gene id: 548476:CAURI_RS05025
uniprot id: C3PFE5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS12745
gene id: 548476:CAURI_RS12745
uniprot id: C3PKC9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS12480
gene id: 548476:CAURI_RS12480
uniprot id: C3PK79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

548476:CAURI RS06515
gene id: 548476:CAURI_RS06515
uniprot id: C3PG86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

548476:CAURI RS06735
gene id: 548476:CAURI_RS06735
uniprot id: C3PGD0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

548476:CAURI RS11715
gene id: 548476:CAURI_RS11715
uniprot id: C3PJE0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

548476:CAURI RS04405
gene id: 548476:CAURI_RS04405
uniprot id: C3PF27
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

548476:CAURI RS02820
gene id: 548476:CAURI_RS02820
uniprot id: C3PLC0
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11635
gene id: 548476:CAURI_RS11635
uniprot id: C3PJC3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

548476:CAURI RS10110
gene id: 548476:CAURI_RS10110
uniprot id: C3PI74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

548476:CAURI RS09890
gene id: 548476:CAURI_RS09890
uniprot id: C3PI36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

548476:CAURI RS00520
gene id: 548476:CAURI_RS00520
uniprot id: C3PJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

548476:CAURI RS02750
gene id: 548476:CAURI_RS02750
uniprot id: C3PLA6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

548476:CAURI RS06205
gene id: 548476:CAURI_RS06205
uniprot id: C3PG26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

548476:CAURI RS08310
gene id: 548476:CAURI_RS08310
uniprot id: C3PH80
names: Similarity
messages: Belongs to the P(II) protein family.

548476:CAURI RS08880
gene id: 548476:CAURI_RS08880
uniprot id: C3PHJ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

548476:CAURI RS11970
gene id: 548476:CAURI_RS11970
uniprot id: C3PJJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

548476:CAURI RS09490
gene id: 548476:CAURI_RS09490
uniprot id: C3PHV6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

548476:CAURI RS01420
gene id: 548476:CAURI_RS01420
uniprot id: C3PJX6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

548476:CAURI RS01840
gene id: 548476:CAURI_RS01840
uniprot id: C3PKJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS06715
gene id: 548476:CAURI_RS06715
uniprot id: C3PGC6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02330
gene id: 548476:CAURI_RS02330
uniprot id: C3PL26
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

548476:CAURI RS02305
gene id: 548476:CAURI_RS02305
uniprot id: C3PL21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

548476:CAURI RS07845
gene id: 548476:CAURI_RS07845
uniprot id: C3PGY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

548476:CAURI RS08705
gene id: 548476:CAURI_RS08705
uniprot id: C3PHF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

548476:CAURI RS09800
gene id: 548476:CAURI_RS09800
uniprot id: C3PI17
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

548476:CAURI RS00050
gene id: 548476:CAURI_RS00050
uniprot id: B3GW52
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

548476:CAURI RS02115
gene id: 548476:CAURI_RS02115
uniprot id: C3PKQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

548476:CAURI RS00800
gene id: 548476:CAURI_RS00800
uniprot id: C3PJ71
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

548476:CAURI RS13060
gene id: 548476:CAURI_RS13060
uniprot id: C3PKX8
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

548476:CAURI RS02440
gene id: 548476:CAURI_RS02440
uniprot id: C3PL47
names: Similarity
messages: Belongs to the WXG100 family.

548476:CAURI RS00845
gene id: 548476:CAURI_RS00845
uniprot id: C3PJ80
names: Similarity
messages: Belongs to the Nudix hydrolase family.

548476:CAURI RS01550
gene id: 548476:CAURI_RS01550
uniprot id: C3PK04
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS03070
gene id: 548476:CAURI_RS03070
uniprot id: C3PEB9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

548476:CAURI RS08475
gene id: 548476:CAURI_RS08475
uniprot id: C3PHB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

548476:CAURI RS10890
gene id: 548476:CAURI_RS10890
uniprot id: C3PIL6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS03110
gene id: 548476:CAURI_RS03110
uniprot id: C3PEC6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

548476:CAURI RS04040
gene id: 548476:CAURI_RS04040
uniprot id: C3PEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

548476:CAURI RS12340
gene id: 548476:CAURI_RS12340
uniprot id: C3PK50
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS07160
gene id: 548476:CAURI_RS07160
uniprot id: C3PGK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

548476:CAURI RS06235
gene id: 548476:CAURI_RS06235
uniprot id: C3PG32
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

548476:CAURI RS01065
gene id: 548476:CAURI_RS01065
uniprot id: C3PJQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

548476:CAURI RS10725
gene id: 548476:CAURI_RS10725
uniprot id: C3PII5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

548476:CAURI RS10645
gene id: 548476:CAURI_RS10645
uniprot id: C3PIG9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

548476:CAURI RS06865
gene id: 548476:CAURI_RS06865
uniprot id: C3PGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

548476:CAURI RS03430
gene id: 548476:CAURI_RS03430
uniprot id: C3PEI9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

548476:CAURI RS09470
gene id: 548476:CAURI_RS09470
uniprot id: C3PHV2
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06615
gene id: 548476:CAURI_RS06615
uniprot id: C3PGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

548476:CAURI RS12335
gene id: 548476:CAURI_RS12335
uniprot id: C3PK49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS06280
gene id: 548476:CAURI_RS06280
uniprot id: C3PG41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

548476:CAURI RS10510
gene id: 548476:CAURI_RS10510
uniprot id: C3PIE7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS10700
gene id: 548476:CAURI_RS10700
uniprot id: C3PII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS07125
gene id: 548476:CAURI_RS07125
uniprot id: C3PGK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

548476:CAURI RS05715
gene id: 548476:CAURI_RS05715
uniprot id: C3PFT3
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07785
gene id: 548476:CAURI_RS07785
uniprot id: C3PGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS12915
gene id: 548476:CAURI_RS12915
uniprot id: C3PKU8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

548476:CAURI RS07260
gene id: 548476:CAURI_RS07260
uniprot id: C3PGM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

548476:CAURI RS08770
gene id: 548476:CAURI_RS08770
uniprot id: C3PHH2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

548476:CAURI RS12475
gene id: 548476:CAURI_RS12475
uniprot id: C3PK78
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS06285
gene id: 548476:CAURI_RS06285
uniprot id: C3PG42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

548476:CAURI RS04355
gene id: 548476:CAURI_RS04355
uniprot id: C3PF17
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

548476:CAURI RS05165
gene id: 548476:CAURI_RS05165
uniprot id: C3PFH3
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

548476:CAURI RS02295
gene id: 548476:CAURI_RS02295
uniprot id: C3PL19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

548476:CAURI RS06425
gene id: 548476:CAURI_RS06425
uniprot id: C3PG69
names: Similarity
messages: Belongs to the UPF0237 family.

548476:CAURI RS06315
gene id: 548476:CAURI_RS06315
uniprot id: C3PG48
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

548476:CAURI RS08240
gene id: 548476:CAURI_RS08240
uniprot id: C3PH66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

548476:CAURI RS09420
gene id: 548476:CAURI_RS09420
uniprot id: C3PHU2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

548476:CAURI RS05405
gene id: 548476:CAURI_RS05405
uniprot id: C3PFM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

548476:CAURI RS06620
gene id: 548476:CAURI_RS06620
uniprot id: C3PGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

548476:CAURI RS04350
gene id: 548476:CAURI_RS04350
uniprot id: C3PF16
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

548476:CAURI RS09100
gene id: 548476:CAURI_RS09100
uniprot id: C3PHN9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

548476:CAURI RS01990
gene id: 548476:CAURI_RS01990
uniprot id: C3PKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

548476:CAURI RS08345
gene id: 548476:CAURI_RS08345
uniprot id: C3PH86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

548476:CAURI RS09810
gene id: 548476:CAURI_RS09810
uniprot id: C3PI19
names: Similarity
messages: Belongs to the phosphohexose mutase family.

548476:CAURI RS05620
gene id: 548476:CAURI_RS05620
uniprot id: C3PFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

548476:CAURI RS08485
gene id: 548476:CAURI_RS08485
uniprot id: C3PHB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

548476:CAURI RS11935
gene id: 548476:CAURI_RS11935
uniprot id: C3PJI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

548476:CAURI RS05510
gene id: 548476:CAURI_RS05510
uniprot id: C3PFP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

548476:CAURI RS04885
gene id: 548476:CAURI_RS04885
uniprot id: C3PFB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

548476:CAURI RS06195
gene id: 548476:CAURI_RS06195
uniprot id: C3PG24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

548476:CAURI RS12295
gene id: 548476:CAURI_RS12295
uniprot id: C3PK41
names: Similarity
messages: Belongs to the universal stress protein A family.

548476:CAURI RS01375
gene id: 548476:CAURI_RS01375
uniprot id: C3PJW7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08685
gene id: 548476:CAURI_RS08685
uniprot id: C3PHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

548476:CAURI RS06225
gene id: 548476:CAURI_RS06225
uniprot id: C3PG30
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

548476:CAURI RS08015
gene id: 548476:CAURI_RS08015
uniprot id: C3PH21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

548476:CAURI RS01140
gene id: 548476:CAURI_RS01140
uniprot id: C3PJS2
names: Similarity
messages: Belongs to the catalase family.

548476:CAURI RS08690
gene id: 548476:CAURI_RS08690
uniprot id: C3PHF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS08930
gene id: 548476:CAURI_RS08930
uniprot id: C3PHK5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

548476:CAURI RS06740
gene id: 548476:CAURI_RS06740
uniprot id: C3PGD1
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

548476:CAURI RS11885
gene id: 548476:CAURI_RS11885
uniprot id: C3PJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS11290
gene id: 548476:CAURI_RS11290
uniprot id: C3PIT7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

548476:CAURI RS08270
gene id: 548476:CAURI_RS08270
uniprot id: C3PH72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

548476:CAURI RS07335
gene id: 548476:CAURI_RS07335
uniprot id: C3PGP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS08545
gene id: 548476:CAURI_RS08545
uniprot id: C3PHC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

548476:CAURI RS08215
gene id: 548476:CAURI_RS08215
uniprot id: C3PH61
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

548476:CAURI RS11855
gene id: 548476:CAURI_RS11855
uniprot id: C3PJG9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS09845
gene id: 548476:CAURI_RS09845
uniprot id: C3PI26
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05825
gene id: 548476:CAURI_RS05825
uniprot id: C3PFV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS03885
gene id: 548476:CAURI_RS03885
uniprot id: C3PES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

548476:CAURI RS00095
gene id: 548476:CAURI_RS00095
uniprot id: B3GW61
names: Similarity
messages: Belongs to the TrpF family.

548476:CAURI RS06160
gene id: 548476:CAURI_RS06160
uniprot id: C3PG17
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

548476:CAURI RS07470
gene id: 548476:CAURI_RS07470
uniprot id: C3PGR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

548476:CAURI RS10815
gene id: 548476:CAURI_RS10815
uniprot id: C3PIK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

548476:CAURI RS03925
gene id: 548476:CAURI_RS03925
uniprot id: C3PET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

548476:CAURI RS04680
gene id: 548476:CAURI_RS04680
uniprot id: C3PF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

548476:CAURI RS06060
gene id: 548476:CAURI_RS06060
uniprot id: C3PFZ7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

548476:CAURI RS05250
gene id: 548476:CAURI_RS05250
uniprot id: C3PFJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

548476:CAURI RS12165
gene id: 548476:CAURI_RS12165
uniprot id: C3PK17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

548476:CAURI RS05355
gene id: 548476:CAURI_RS05355
uniprot id: C3PFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

548476:CAURI RS12570
gene id: 548476:CAURI_RS12570
uniprot id: C3PK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

548476:CAURI RS11070
gene id: 548476:CAURI_RS11070
uniprot id: C3PIQ1
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

548476:CAURI RS03835
gene id: 548476:CAURI_RS03835
uniprot id: C3PER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

548476:CAURI RS07110
gene id: 548476:CAURI_RS07110
uniprot id: C3PGJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

548476:CAURI RS06420
gene id: 548476:CAURI_RS06420
uniprot id: C3PG68
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

548476:CAURI RS01225
gene id: 548476:CAURI_RS01225
uniprot id: C3PJT7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS03415
gene id: 548476:CAURI_RS03415
uniprot id: C3PEI6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

548476:CAURI RS11100
gene id: 548476:CAURI_RS11100
uniprot id: C3PIQ7
names: Similarity
messages: Belongs to the fructosamine kinase family.

548476:CAURI RS05500
gene id: 548476:CAURI_RS05500
uniprot id: C3PFN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

548476:CAURI RS11170
gene id: 548476:CAURI_RS11170
uniprot id: C3PIS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

548476:CAURI RS06845
gene id: 548476:CAURI_RS06845
uniprot id: C3PGF1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

548476:CAURI RS08580
gene id: 548476:CAURI_RS08580
uniprot id: C3PHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

548476:CAURI RS05725
gene id: 548476:CAURI_RS05725
uniprot id: C3PFT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

548476:CAURI RS08150
gene id: 548476:CAURI_RS08150
uniprot id: C3PH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

548476:CAURI RS02845
gene id: 548476:CAURI_RS02845
uniprot id: C3PLC5
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS03875
gene id: 548476:CAURI_RS03875
uniprot id: C3PES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

548476:CAURI RS07620
gene id: 548476:CAURI_RS07620
uniprot id: C3PGU2
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

548476:CAURI RS06140
gene id: 548476:CAURI_RS06140
uniprot id: C3PG13
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

548476:CAURI RS05495
gene id: 548476:CAURI_RS05495
uniprot id: C3PFN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

548476:CAURI RS06045
gene id: 548476:CAURI_RS06045
uniprot id: C3PFZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

548476:CAURI RS07835
gene id: 548476:CAURI_RS07835
uniprot id: C3PGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS09410
gene id: 548476:CAURI_RS09410
uniprot id: C3PHU0
names: Similarity
messages: Belongs to the Fur family.

548476:CAURI RS07285
gene id: 548476:CAURI_RS07285
uniprot id: C3PGN2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

548476:CAURI RS07705
gene id: 548476:CAURI_RS07705
uniprot id: C3PGV9
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

548476:CAURI RS06215
gene id: 548476:CAURI_RS06215
uniprot id: C3PG28
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

548476:CAURI RS08885
gene id: 548476:CAURI_RS08885
uniprot id: C3PHJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

548476:CAURI RS00185
gene id: 548476:CAURI_RS00185
uniprot id: C3PE80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

548476:CAURI RS02910
gene id: 548476:CAURI_RS02910
uniprot id: C3PLD7
names: Similarity
messages: Belongs to the citrate synthase family.

548476:CAURI RS11005
gene id: 548476:CAURI_RS11005
uniprot id: C3PIN8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

548476:CAURI RS08460
gene id: 548476:CAURI_RS08460
uniprot id: C3PHA9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

548476:CAURI RS05525
gene id: 548476:CAURI_RS05525
uniprot id: C3PFP4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

548476:CAURI RS09465
gene id: 548476:CAURI_RS09465
uniprot id: C3PHV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

548476:CAURI RS07190
gene id: 548476:CAURI_RS07190
uniprot id: C3PGL4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS13205
gene id: 548476:CAURI_RS13205
uniprot id: C3PL05
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

548476:CAURI RS01655
gene id: 548476:CAURI_RS01655
uniprot id: C3PKG1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

548476:CAURI RS11755
gene id: 548476:CAURI_RS11755
uniprot id: C3PJE8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

548476:CAURI RS08175
gene id: 548476:CAURI_RS08175
uniprot id: C3PH53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

548476:CAURI RS07045
gene id: 548476:CAURI_RS07045
uniprot id: C3PGI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS03375
gene id: 548476:CAURI_RS03375
uniprot id: C3PEH8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

548476:CAURI RS02450
gene id: 548476:CAURI_RS02450
uniprot id: C3PL49
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

548476:CAURI RS07770
gene id: 548476:CAURI_RS07770
uniprot id: C3PGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

548476:CAURI RS03450
gene id: 548476:CAURI_RS03450
uniprot id: C3PEJ3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

548476:CAURI RS11280
gene id: 548476:CAURI_RS11280
uniprot id: C3PIT6
names: Similarity
messages: Belongs to the CsoR family.

548476:CAURI RS09735
gene id: 548476:CAURI_RS09735
uniprot id: C3PI05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

548476:CAURI RS05800
gene id: 548476:CAURI_RS05800
uniprot id: C3PFU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

548476:CAURI RS05000
gene id: 548476:CAURI_RS05000
uniprot id: C3PFE0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

548476:CAURI RS06085
gene id: 548476:CAURI_RS06085
uniprot id: C3PG02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

548476:CAURI RS09830
gene id: 548476:CAURI_RS09830
uniprot id: C3PI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

548476:CAURI RS02320
gene id: 548476:CAURI_RS02320
uniprot id: C3PL24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

548476:CAURI RS12650
gene id: 548476:CAURI_RS12650
uniprot id: C3PKB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

548476:CAURI RS06145
gene id: 548476:CAURI_RS06145
uniprot id: C3PG14
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

548476:CAURI RS04895
gene id: 548476:CAURI_RS04895
uniprot id: C3PFC0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS03735
gene id: 548476:CAURI_RS03735
uniprot id: C3PEP9
names: Similarity
messages: Belongs to the peptidase S16 family.

548476:CAURI RS08695
gene id: 548476:CAURI_RS08695
uniprot id: C3PHF7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS03700
gene id: 548476:CAURI_RS03700
uniprot id: C3PEP2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

548476:CAURI RS06210
gene id: 548476:CAURI_RS06210
uniprot id: C3PG27
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

548476:CAURI RS07875
gene id: 548476:CAURI_RS07875
uniprot id: C3PGZ4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS04675
gene id: 548476:CAURI_RS04675
uniprot id: C3PF80
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

548476:CAURI RS06945
gene id: 548476:CAURI_RS06945
uniprot id: C3PGH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS11705
gene id: 548476:CAURI_RS11705
uniprot id: C3PJD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS02790
gene id: 548476:CAURI_RS02790
uniprot id: C3PLB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

548476:CAURI RS10810
gene id: 548476:CAURI_RS10810
uniprot id: C3PIK0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

548476:CAURI RS09795
gene id: 548476:CAURI_RS09795
uniprot id: C3PI16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

548476:CAURI RS00580
gene id: 548476:CAURI_RS00580
uniprot id: C3PJ28
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS03870
gene id: 548476:CAURI_RS03870
uniprot id: C3PES4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

548476:CAURI RS07735
gene id: 548476:CAURI_RS07735
uniprot id: C3PGW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

548476:CAURI RS05805
gene id: 548476:CAURI_RS05805
uniprot id: C3PFV0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

548476:CAURI RS08110
gene id: 548476:CAURI_RS08110
uniprot id: C3PH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

548476:CAURI RS08105
gene id: 548476:CAURI_RS08105
uniprot id: C3PH39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

548476:CAURI RS08155
gene id: 548476:CAURI_RS08155
uniprot id: C3PH49
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS02060
gene id: 548476:CAURI_RS02060
uniprot id: C3PKP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

548476:CAURI RS11480
gene id: 548476:CAURI_RS11480
uniprot id: C3PJ94
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

548476:CAURI RS04635
gene id: 548476:CAURI_RS04635
uniprot id: C3PF72
names: Similarity
messages: Belongs to the HIBADH-related family.

548476:CAURI RS01910
gene id: 548476:CAURI_RS01910
uniprot id: C3PKL3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

548476:CAURI RS11085
gene id: 548476:CAURI_RS11085
uniprot id: C3PIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

548476:CAURI RS08665
gene id: 548476:CAURI_RS08665
uniprot id: C3PHF1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

548476:CAURI RS12040
gene id: 548476:CAURI_RS12040
uniprot id: C3PJK6
names: Similarity
messages: Belongs to the class-I fumarase family.

548476:CAURI RS05060
gene id: 548476:CAURI_RS05060
uniprot id: C3PFF2
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06260
gene id: 548476:CAURI_RS06260
uniprot id: C3PG37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

548476:CAURI RS06575
gene id: 548476:CAURI_RS06575
uniprot id: C3PG98
names: Similarity
messages: Belongs to the peptidase M18 family.

548476:CAURI RS08970
gene id: 548476:CAURI_RS08970
uniprot id: C3PHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

548476:CAURI RS03240
gene id: 548476:CAURI_RS03240
uniprot id: C3PEF2
names: Similarity
messages: Belongs to the DapA family.

548476:CAURI RS07410
gene id: 548476:CAURI_RS07410
uniprot id: C3PGQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

548476:CAURI RS10705
gene id: 548476:CAURI_RS10705
uniprot id: C3PII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS00785
gene id: 548476:CAURI_RS00785
uniprot id: C3PJ68
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

548476:CAURI RS07085
gene id: 548476:CAURI_RS07085
uniprot id: C3PGJ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

548476:CAURI RS13105
gene id: 548476:CAURI_RS13105
uniprot id: C3PKY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

548476:CAURI RS10720
gene id: 548476:CAURI_RS10720
uniprot id: C3PII4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

548476:CAURI RS11300
gene id: 548476:CAURI_RS11300
uniprot id: C3PIT9
names: Similarity
messages: Belongs to the PhoU family.

548476:CAURI RS13255
gene id: 548476:CAURI_RS13255
uniprot id: C3PL14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

548476:CAURI RS11440
gene id: 548476:CAURI_RS11440
uniprot id: C3PIW8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

548476:CAURI RS12070
gene id: 548476:CAURI_RS12070
uniprot id: C3PJL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS07300
gene id: 548476:CAURI_RS07300
uniprot id: C3PGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS01465
gene id: 548476:CAURI_RS01465
uniprot id: C3PJY7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

548476:CAURI RS06050
gene id: 548476:CAURI_RS06050
uniprot id: C3PFZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

548476:CAURI RS03260
gene id: 548476:CAURI_RS03260
uniprot id: C3PEF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

548476:CAURI RS01865
gene id: 548476:CAURI_RS01865
uniprot id: C3PKK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

548476:CAURI RS09500
gene id: 548476:CAURI_RS09500
uniprot id: C3PHV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

548476:CAURI RS07155
gene id: 548476:CAURI_RS07155
uniprot id: C3PGK7
names: Similarity
messages: Belongs to the universal stress protein A family.

548476:CAURI RS02555
gene id: 548476:CAURI_RS02555
uniprot id: C3PL68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

548476:CAURI RS12160
gene id: 548476:CAURI_RS12160
uniprot id: C3PK16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS06890
gene id: 548476:CAURI_RS06890
uniprot id: C3PGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

548476:CAURI RS02435
gene id: 548476:CAURI_RS02435
uniprot id: C3PL46
names: Similarity
messages: Belongs to the WXG100 family.

548476:CAURI RS07435
gene id: 548476:CAURI_RS07435
uniprot id: C3PGR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

548476:CAURI RS07480
gene id: 548476:CAURI_RS07480
uniprot id: C3PGS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS05885
gene id: 548476:CAURI_RS05885
uniprot id: C3PFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

548476:CAURI RS01625
gene id: 548476:CAURI_RS01625
uniprot id: C3PKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

548476:CAURI RS01795
gene id: 548476:CAURI_RS01795
uniprot id: C3PKI9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05950
gene id: 548476:CAURI_RS05950
uniprot id: C3PFX9
names: Similarity
messages: Belongs to the isochorismate synthase family.

548476:CAURI RS13080
gene id: 548476:CAURI_RS13080
uniprot id: C3PKY2
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

548476:CAURI RS02565
gene id: 548476:CAURI_RS02565
uniprot id: C3PL70
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

548476:CAURI RS03005
gene id: 548476:CAURI_RS03005
uniprot id: C3PEA6
names: Similarity
messages: Belongs to the AccD/PCCB family.

548476:CAURI RS08820
gene id: 548476:CAURI_RS08820
uniprot id: C3PHI3
names: Similarity
messages: Belongs to the peptidase C40 family.

548476:CAURI RS11850
gene id: 548476:CAURI_RS11850
uniprot id: C3PJG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

548476:CAURI RS03830
gene id: 548476:CAURI_RS03830
uniprot id: C3PER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

548476:CAURI RS02390
gene id: 548476:CAURI_RS02390
uniprot id: C3PL37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

548476:CAURI RS11895
gene id: 548476:CAURI_RS11895
uniprot id: C3PJH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

548476:CAURI RS11655
gene id: 548476:CAURI_RS11655
uniprot id: C3PJC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

548476:CAURI RS02375
gene id: 548476:CAURI_RS02375
uniprot id: C3PL34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

548476:CAURI RS02815
gene id: 548476:CAURI_RS02815
uniprot id: C3PLB9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

548476:CAURI RS02000
gene id: 548476:CAURI_RS02000
uniprot id: C3PKM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

548476:CAURI RS00485
gene id: 548476:CAURI_RS00485
uniprot id: C3PJ10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

548476:CAURI RS11310
gene id: 548476:CAURI_RS11310
uniprot id: C3PIU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

548476:CAURI RS09450
gene id: 548476:CAURI_RS09450
uniprot id: C3PHU8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

548476:CAURI RS04995
gene id: 548476:CAURI_RS04995
uniprot id: C3PFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

548476:CAURI RS13795
gene id: 548476:CAURI_RS13795
uniprot id: C3PGM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

548476:CAURI RS07925
gene id: 548476:CAURI_RS07925
uniprot id: C3PH04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

548476:CAURI RS07230
gene id: 548476:CAURI_RS07230
uniprot id: C3PGM1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

548476:CAURI RS10990
gene id: 548476:CAURI_RS10990
uniprot id: C3PIN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

548476:CAURI RS05200
gene id: 548476:CAURI_RS05200
uniprot id: C3PFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

548476:CAURI RS05555
gene id: 548476:CAURI_RS05555
uniprot id: C3PFQ0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

548476:CAURI RS11295
gene id: 548476:CAURI_RS11295
uniprot id: C3PIT8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

548476:CAURI RS12125
gene id: 548476:CAURI_RS12125
uniprot id: C3PJM4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

548476:CAURI RS01055
gene id: 548476:CAURI_RS01055
uniprot id: C3PJQ4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

548476:CAURI RS12085
gene id: 548476:CAURI_RS12085
uniprot id: C3PJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

548476:CAURI RS02095
gene id: 548476:CAURI_RS02095
uniprot id: C3PKP7
names: Similarity
messages: Belongs to the asp23 family.

548476:CAURI RS05855
gene id: 548476:CAURI_RS05855
uniprot id: C3PFW1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

548476:CAURI RS07730
gene id: 548476:CAURI_RS07730
uniprot id: C3PGW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

548476:CAURI RS03915
gene id: 548476:CAURI_RS03915
uniprot id: C3PET3
names: Similarity
messages: Belongs to the peptidase M20A family.

548476:CAURI RS11145
gene id: 548476:CAURI_RS11145
uniprot id: C3PIR5
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05590
gene id: 548476:CAURI_RS05590
uniprot id: C3PFQ7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07380
gene id: 548476:CAURI_RS07380
uniprot id: C3PGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS08595
gene id: 548476:CAURI_RS08595
uniprot id: C3PHD7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

548476:CAURI RS00945
gene id: 548476:CAURI_RS00945
uniprot id: C3PJN4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08635
gene id: 548476:CAURI_RS08635
uniprot id: C3PHE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

548476:CAURI RS01835
gene id: 548476:CAURI_RS01835
uniprot id: C3PKJ7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

548476:CAURI RS09860
gene id: 548476:CAURI_RS09860
uniprot id: C3PI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

548476:CAURI RS04215
gene id: 548476:CAURI_RS04215
uniprot id: C3PEY9
names: Similarity
messages: Belongs to the FPG family.

548476:CAURI RS12740
gene id: 548476:CAURI_RS12740
uniprot id: C3PKC8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

548476:CAURI RS11555
gene id: 548476:CAURI_RS11555
uniprot id: C3PJA7
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

548476:CAURI RS11760
gene id: 548476:CAURI_RS11760
uniprot id: C3PJE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

548476:CAURI RS09075
gene id: 548476:CAURI_RS09075
uniprot id: C3PHN5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

548476:CAURI RS11050
gene id: 548476:CAURI_RS11050
uniprot id: C3PIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

548476:CAURI RS04015
gene id: 548476:CAURI_RS04015
uniprot id: C3PEV1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

548476:CAURI RS01660
gene id: 548476:CAURI_RS01660
uniprot id: C3PKG2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

548476:CAURI RS04655
gene id: 548476:CAURI_RS04655
uniprot id: C3PF76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS06500
gene id: 548476:CAURI_RS06500
uniprot id: C3PG84
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

548476:CAURI RS03990
gene id: 548476:CAURI_RS03990
uniprot id: C3PEU6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

548476:CAURI RS05095
gene id: 548476:CAURI_RS05095
uniprot id: C3PFF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

548476:CAURI RS08135
gene id: 548476:CAURI_RS08135
uniprot id: C3PH45
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

548476:CAURI RS04425
gene id: 548476:CAURI_RS04425
uniprot id: C3PF32
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02900
gene id: 548476:CAURI_RS02900
uniprot id: C3PLD5
names: Similarity
messages: Belongs to the PrpD family.

548476:CAURI RS06240
gene id: 548476:CAURI_RS06240
uniprot id: C3PG33
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

548476:CAURI RS04765
gene id: 548476:CAURI_RS04765
uniprot id: C3PF97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

548476:CAURI RS00150
gene id: 548476:CAURI_RS00150
uniprot id: C3PE74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

548476:CAURI RS02135
gene id: 548476:CAURI_RS02135
uniprot id: C3PKQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

548476:CAURI RS08180
gene id: 548476:CAURI_RS08180
uniprot id: C3PH54
names: Similarity
messages: Belongs to the DprA/Smf family.

548476:CAURI RS06305
gene id: 548476:CAURI_RS06305
uniprot id: C3PG46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

548476:CAURI RS04395
gene id: 548476:CAURI_RS04395
uniprot id: C3PF25
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

548476:CAURI RS00710
gene id: 548476:CAURI_RS00710
uniprot id: C3PJ54
names: Similarity
messages: Belongs to the ABC transporter superfamily.

548476:CAURI RS00250
gene id: 548476:CAURI_RS00250
uniprot id: C3PE90
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

548476:CAURI RS02500
gene id: 548476:CAURI_RS02500
uniprot id: C3PL57
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

548476:CAURI RS12105
gene id: 548476:CAURI_RS12105
uniprot id: C3PJL9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

548476:CAURI RS10735
gene id: 548476:CAURI_RS10735
uniprot id: C3PII7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

548476:CAURI RS05505
gene id: 548476:CAURI_RS05505
uniprot id: C3PFP0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

548476:CAURI RS07100
gene id: 548476:CAURI_RS07100
uniprot id: C3PGJ6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS05010
gene id: 548476:CAURI_RS05010
uniprot id: C3PFE2
names: Similarity
messages: Belongs to the peptidase C56 family.

548476:CAURI RS09835
gene id: 548476:CAURI_RS09835
uniprot id: C3PI24
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

548476:CAURI RS13185
gene id: 548476:CAURI_RS13185
uniprot id: C3PL01
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11065
gene id: 548476:CAURI_RS11065
uniprot id: C3PIQ0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

548476:CAURI RS11485
gene id: 548476:CAURI_RS11485
uniprot id: C3PJ95
names: Similarity
messages: Belongs to the GARS family.

548476:CAURI RS11020
gene id: 548476:CAURI_RS11020
uniprot id: C3PIP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

548476:CAURI RS06720
gene id: 548476:CAURI_RS06720
uniprot id: C3PGC7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS02325
gene id: 548476:CAURI_RS02325
uniprot id: C3PL25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

548476:CAURI RS12035
gene id: 548476:CAURI_RS12035
uniprot id: C3PJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

548476:CAURI RS10935
gene id: 548476:CAURI_RS10935
uniprot id: C3PIM5
names: Similarity
messages: Belongs to the peptidase S33 family.

548476:CAURI RS02055
gene id: 548476:CAURI_RS02055
uniprot id: C3PKN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

548476:CAURI RS03250
gene id: 548476:CAURI_RS03250
uniprot id: C3PEF3
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

548476:CAURI RS00565
gene id: 548476:CAURI_RS00565
uniprot id: C3PJ26
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

548476:CAURI RS04480
gene id: 548476:CAURI_RS04480
uniprot id: C3PF42
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

548476:CAURI RS11645
gene id: 548476:CAURI_RS11645
uniprot id: C3PJC5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

548476:CAURI RS12855
gene id: 548476:CAURI_RS12855
uniprot id: C3PKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

548476:CAURI RS04815
gene id: 548476:CAURI_RS04815
uniprot id: C3PFA7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

548476:CAURI RS03520
gene id: 548476:CAURI_RS03520
uniprot id: C3PEK7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

548476:CAURI RS11770
gene id: 548476:CAURI_RS11770
uniprot id: C3PJF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

548476:CAURI RS09355
gene id: 548476:CAURI_RS09355
uniprot id: C3PHT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

548476:CAURI RS06155
gene id: 548476:CAURI_RS06155
uniprot id: C3PG16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

548476:CAURI RS08540
gene id: 548476:CAURI_RS08540
uniprot id: C3PHC6
names: Similarity
messages: Belongs to the IMPACT family.

548476:CAURI RS01325
gene id: 548476:CAURI_RS01325
uniprot id: C3PJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

548476:CAURI RS03365
gene id: 548476:CAURI_RS03365
uniprot id: C3PEH6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

548476:CAURI RS13225
gene id: 548476:CAURI_RS13225
uniprot id: C3PL09
names: Similarity
messages: Belongs to the ParB family.

548476:CAURI RS01560
gene id: 548476:CAURI_RS01560
uniprot id: C3PK06
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

548476:CAURI RS09445
gene id: 548476:CAURI_RS09445
uniprot id: C3PHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

548476:CAURI RS05610
gene id: 548476:CAURI_RS05610
uniprot id: C3PFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

548476:CAURI RS13055
gene id: 548476:CAURI_RS13055
uniprot id: C3PKX7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07580
gene id: 548476:CAURI_RS07580
uniprot id: C3PGT4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS03760
gene id: 548476:CAURI_RS03760
uniprot id: C3PEQ3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

548476:CAURI RS07975
gene id: 548476:CAURI_RS07975
uniprot id: C3PH13
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

548476:CAURI RS05385
gene id: 548476:CAURI_RS05385
uniprot id: C3PFL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

548476:CAURI RS05085
gene id: 548476:CAURI_RS05085
uniprot id: C3PFF7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

548476:CAURI RS04285
gene id: 548476:CAURI_RS04285
uniprot id: C3PF03
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

548476:CAURI RS01360
gene id: 548476:CAURI_RS01360
uniprot id: C3PJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

548476:CAURI RS06290
gene id: 548476:CAURI_RS06290
uniprot id: C3PG43
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

548476:CAURI RS06590
gene id: 548476:CAURI_RS06590
uniprot id: C3PGA1
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

548476:CAURI RS08330
gene id: 548476:CAURI_RS08330
uniprot id: C3PH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS08905
gene id: 548476:CAURI_RS08905
uniprot id: C3PHK0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

548476:CAURI RS11520
gene id: 548476:CAURI_RS11520
uniprot id: C3PJA1
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS10130
gene id: 548476:CAURI_RS10130
uniprot id: C3PI78
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

548476:CAURI RS06105
gene id: 548476:CAURI_RS06105
uniprot id: C3PG06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

548476:CAURI RS01670
gene id: 548476:CAURI_RS01670
uniprot id: C3PKG4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

548476:CAURI RS11620
gene id: 548476:CAURI_RS11620
uniprot id: C3PJC0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

548476:CAURI RS11435
gene id: 548476:CAURI_RS11435
uniprot id: C3PIW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

548476:CAURI RS07750
gene id: 548476:CAURI_RS07750
uniprot id: C3PGW9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

548476:CAURI RS08200
gene id: 548476:CAURI_RS08200
uniprot id: C3PH58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

548476:CAURI RS06180
gene id: 548476:CAURI_RS06180
uniprot id: C3PG21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

548476:CAURI RS12485
gene id: 548476:CAURI_RS12485
uniprot id: C3PK80
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

548476:CAURI RS06150
gene id: 548476:CAURI_RS06150
uniprot id: C3PG15
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

548476:CAURI RS08650
gene id: 548476:CAURI_RS08650
uniprot id: C3PHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

548476:CAURI RS06920
gene id: 548476:CAURI_RS06920
uniprot id: C3PGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

548476:CAURI RS02125
gene id: 548476:CAURI_RS02125
uniprot id: C3PKQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

548476:CAURI RS00865
gene id: 548476:CAURI_RS00865
uniprot id: C3PJ84
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11880
gene id: 548476:CAURI_RS11880
uniprot id: C3PJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS06810
gene id: 548476:CAURI_RS06810
uniprot id: C3PGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

548476:CAURI RS01135
gene id: 548476:CAURI_RS01135
uniprot id: C3PJS1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

548476:CAURI RS01315
gene id: 548476:CAURI_RS01315
uniprot id: C3PJV6
names: Subcellular Location Annotation
messages: Cytoplasm

548476:CAURI RS07935
gene id: 548476:CAURI_RS07935
uniprot id: C3PH06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

548476:CAURI RS08795
gene id: 548476:CAURI_RS08795
uniprot id: C3PHH7
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

548476:CAURI RS10940
gene id: 548476:CAURI_RS10940
uniprot id: C3PIM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

548476:CAURI RS08710
gene id: 548476:CAURI_RS08710
uniprot id: C3PHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

548476:CAURI RS01280
gene id: 548476:CAURI_RS01280
uniprot id: C3PJU9
names: Similarity
messages: Belongs to the GSP E family.

548476:CAURI RS12200
gene id: 548476:CAURI_RS12200
uniprot id: C3PK24
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

548476:CAURI RS02945
gene id: 548476:CAURI_RS02945
uniprot id: C3PLE3
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

548476:CAURI RS01945
gene id: 548476:CAURI_RS01945
uniprot id: C3PKL6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

548476:CAURI RS08210
gene id: 548476:CAURI_RS08210
uniprot id: C3PH60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

548476:CAURI RS01095
gene id: 548476:CAURI_RS01095
uniprot id: C3PJR3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

548476:CAURI RS11565
gene id: 548476:CAURI_RS11565
uniprot id: C3PJA9
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

548476:CAURI RS05675
gene id: 548476:CAURI_RS05675
uniprot id: C3PFS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

548476:CAURI RS07040
gene id: 548476:CAURI_RS07040
uniprot id: C3PGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

548476:CAURI RS06940
gene id: 548476:CAURI_RS06940
uniprot id: C3PGH0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

548476:CAURI RS11055
gene id: 548476:CAURI_RS11055
uniprot id: C3PIP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

548476:CAURI RS04695
gene id: 548476:CAURI_RS04695
uniprot id: C3PF84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

548476:CAURI RS13160
gene id: 548476:CAURI_RS13160
uniprot id: C3PKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

548476:CAURI RS11900
gene id: 548476:CAURI_RS11900
uniprot id: C3PJH8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

548476:CAURI RS08095
gene id: 548476:CAURI_RS08095
uniprot id: C3PH37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

548476:CAURI RS05350
gene id: 548476:CAURI_RS05350
uniprot id: C3PFL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

548476:CAURI RS11980
gene id: 548476:CAURI_RS11980
uniprot id: C3PJJ4
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06325
gene id: 548476:CAURI_RS06325
uniprot id: C3PG50
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07665
gene id: 548476:CAURI_RS07665
uniprot id: C3PGV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS02625
gene id: 548476:CAURI_RS02625
uniprot id: C3PL81
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS00160
gene id: 548476:CAURI_RS00160
uniprot id: C3PE76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

548476:CAURI RS02150
gene id: 548476:CAURI_RS02150
uniprot id: C3PKQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

548476:CAURI RS07400
gene id: 548476:CAURI_RS07400
uniprot id: C3PGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

548476:CAURI RS07370
gene id: 548476:CAURI_RS07370
uniprot id: C3PGP9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

548476:CAURI RS06300
gene id: 548476:CAURI_RS06300
uniprot id: C3PG45
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS02895
gene id: 548476:CAURI_RS02895
uniprot id: C3PLD4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

548476:CAURI RS07910
gene id: 548476:CAURI_RS07910
uniprot id: C3PH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

548476:CAURI RS05390
gene id: 548476:CAURI_RS05390
uniprot id: C3PFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

548476:CAURI RS07905
gene id: 548476:CAURI_RS07905
uniprot id: C3PH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

548476:CAURI RS12725
gene id: 548476:CAURI_RS12725
uniprot id: C3PKC5
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07615
gene id: 548476:CAURI_RS07615
uniprot id: C3PGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

548476:CAURI RS08415
gene id: 548476:CAURI_RS08415
uniprot id: C3PHA0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

548476:CAURI RS12985
gene id: 548476:CAURI_RS12985
uniprot id: C3PKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

548476:CAURI RS05615
gene id: 548476:CAURI_RS05615
uniprot id: C3PFR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

548476:CAURI RS09865
gene id: 548476:CAURI_RS09865
uniprot id: C3PI30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS07880
gene id: 548476:CAURI_RS07880
uniprot id: C3PGZ5
names: Similarity
messages: Belongs to the PspA/IM30 family.

548476:CAURI RS06760
gene id: 548476:CAURI_RS06760
uniprot id: C3PGD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

548476:CAURI RS07540
gene id: 548476:CAURI_RS07540
uniprot id: C3PGS6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS11390
gene id: 548476:CAURI_RS11390
uniprot id: C3PIV7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

548476:CAURI RS02760
gene id: 548476:CAURI_RS02760
uniprot id: C3PLA8
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS06685
gene id: 548476:CAURI_RS06685
uniprot id: C3PGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS08890
gene id: 548476:CAURI_RS08890
uniprot id: C3PHJ7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

548476:CAURI RS09400
gene id: 548476:CAURI_RS09400
uniprot id: C3PHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

548476:CAURI RS12710
gene id: 548476:CAURI_RS12710
uniprot id: C3PKC2
names: Similarity
messages: Belongs to the thioredoxin family.

548476:CAURI RS04575
gene id: 548476:CAURI_RS04575
uniprot id: C3PF60
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

548476:CAURI RS01690
gene id: 548476:CAURI_RS01690
uniprot id: C3PKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

548476:CAURI RS07425
gene id: 548476:CAURI_RS07425
uniprot id: C3PGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

548476:CAURI RS03435
gene id: 548476:CAURI_RS03435
uniprot id: C3PEJ0
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS10655
gene id: 548476:CAURI_RS10655
uniprot id: C3PIH1
names: Similarity
messages: Belongs to the peptidase M1 family.

548476:CAURI RS09435
gene id: 548476:CAURI_RS09435
uniprot id: C3PHU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

548476:CAURI RS04710
gene id: 548476:CAURI_RS04710
uniprot id: C3PF87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

548476:CAURI RS12895
gene id: 548476:CAURI_RS12895
uniprot id: C3PKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

548476:CAURI RS10995
gene id: 548476:CAURI_RS10995
uniprot id: C3PIN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

548476:CAURI RS12115
gene id: 548476:CAURI_RS12115
uniprot id: C3PJM2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

548476:CAURI RS03585
gene id: 548476:CAURI_RS03585
uniprot id: C3PEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

548476:CAURI RS07670
gene id: 548476:CAURI_RS07670
uniprot id: C3PGV2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

548476:CAURI RS09525
gene id: 548476:CAURI_RS09525
uniprot id: C3PHW3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

548476:CAURI RS03210
gene id: 548476:CAURI_RS03210
uniprot id: C3PEE6
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS08910
gene id: 548476:CAURI_RS08910
uniprot id: C3PHK1
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS13015
gene id: 548476:CAURI_RS13015
uniprot id: C3PKW9
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07390
gene id: 548476:CAURI_RS07390
uniprot id: C3PGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

548476:CAURI RS01370
gene id: 548476:CAURI_RS01370
uniprot id: C3PJW6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

548476:CAURI RS02020
gene id: 548476:CAURI_RS02020
uniprot id: C3PKN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

548476:CAURI RS04335
gene id: 548476:CAURI_RS04335
uniprot id: C3PF13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

548476:CAURI RS09360
gene id: 548476:CAURI_RS09360
uniprot id: C3PHT1
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

548476:CAURI RS04255
gene id: 548476:CAURI_RS04255
uniprot id: C3PEZ7
names: Subcellular Location Annotation
messages: Membrane

548476:CAURI RS07090
gene id: 548476:CAURI_RS07090
uniprot id: C3PGJ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

548476:CAURI RS01080
gene id: 548476:CAURI_RS01080
uniprot id: C3PJR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

548476:CAURI RS02835
gene id: 548476:CAURI_RS02835
uniprot id: C3PLC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

548476:CAURI RS01050
gene id: 548476:CAURI_RS01050
uniprot id: C3PJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

548476:CAURI RS06820
gene id: 548476:CAURI_RS06820
uniprot id: C3PGE7
names: Similarity
messages: Belongs to the UPF0225 family.

548476:CAURI RS07790
gene id: 548476:CAURI_RS07790
uniprot id: C3PGX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

548476:CAURI RS06365
gene id: 548476:CAURI_RS06365
uniprot id: C3PG58
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

548476:CAURI RS11775
gene id: 548476:CAURI_RS11775
uniprot id: C3PJF2
names: Similarity
messages: Belongs to the peptidase S13 family.

548476:CAURI RS00555
gene id: 548476:CAURI_RS00555
uniprot id: C3PJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS07330
gene id: 548476:CAURI_RS07330
uniprot id: C3PGP1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

548476:CAURI RS01940
gene id: 548476:CAURI_RS01940
uniprot id: C3PKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

548476:CAURI RS10910
gene id: 548476:CAURI_RS10910
uniprot id: C3PIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

548476:CAURI RS04735
gene id: 548476:CAURI_RS04735
uniprot id: C3PF92
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

548476:CAURI RS09965
gene id: 548476:CAURI_RS09965
uniprot id: C3PI49
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

548476:CAURI RS00590
gene id: 548476:CAURI_RS00590
uniprot id: C3PJ30
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

548476:CAURI RS08920
gene id: 548476:CAURI_RS08920
uniprot id: C3PHK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

548476:CAURI RS07075
gene id: 548476:CAURI_RS07075
uniprot id: C3PGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

548476:CAURI RS11415
gene id: 548476:CAURI_RS11415
uniprot id: C3PIW2
names: Similarity
messages: Belongs to the CsoR family.

548476:CAURI RS05370
gene id: 548476:CAURI_RS05370
uniprot id: C3PFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

548476:CAURI RS06495
gene id: 548476:CAURI_RS06495
uniprot id: C3PG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

548476:CAURI RS03460
gene id: 548476:CAURI_RS03460
uniprot id: C3PEJ5
names: Similarity
messages: Belongs to the TPP enzyme family.

548476:CAURI RS02365
gene id: 548476:CAURI_RS02365
uniprot id: C3PL32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

548476:CAURI RS06380
gene id: 548476:CAURI_RS06380
uniprot id: C3PG61
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

548476:CAURI RS02495
gene id: 548476:CAURI_RS02495
uniprot id: C3PL56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

548476:CAURI RS08000
gene id: 548476:CAURI_RS08000
uniprot id: C3PH18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

548476:CAURI RS06750
gene id: 548476:CAURI_RS06750
uniprot id: C3PGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

548476:CAURI RS02780
gene id: 548476:CAURI_RS02780
uniprot id: C3PLB2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

548476:CAURI RS07745
gene id: 548476:CAURI_RS07745
uniprot id: C3PGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

548476:CAURI RS01220
gene id: 548476:CAURI_RS01220
uniprot id: C3PJT6
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.