543526:HTUR RS21025
gene id: 543526:HTUR_RS21025
uniprot id: D2S166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS21930
gene id: 543526:HTUR_RS21930
uniprot id: D2S1P6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS05355
gene id: 543526:HTUR_RS05355
uniprot id: D2RZ49
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

543526:HTUR RS20275
gene id: 543526:HTUR_RS20275
uniprot id: D2S0R3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

543526:HTUR RS16510
gene id: 543526:HTUR_RS16510
uniprot id: D2RPR5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

543526:HTUR RS08640
gene id: 543526:HTUR_RS08640
uniprot id: D2RS63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

543526:HTUR RS23220
gene id: 543526:HTUR_RS23220
uniprot id: D2S2G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

543526:HTUR RS08825
gene id: 543526:HTUR_RS08825
uniprot id: D2RSA1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07640
gene id: 543526:HTUR_RS07640
uniprot id: D2RQW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

543526:HTUR RS03385
gene id: 543526:HTUR_RS03385
uniprot id: D2RWI4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS02515
gene id: 543526:HTUR_RS02515
uniprot id: D2RVN6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS21855
gene id: 543526:HTUR_RS21855
uniprot id: D2S1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS20155
gene id: 543526:HTUR_RS20155
uniprot id: D2S0P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS03705
gene id: 543526:HTUR_RS03705
uniprot id: D2RX28
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12315
gene id: 543526:HTUR_RS12315
uniprot id: D2RVU2
names: Similarity
messages: Belongs to the PEPCase type 1 family.

543526:HTUR RS16595
gene id: 543526:HTUR_RS16595
uniprot id: D2RPT2
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS13660
gene id: 543526:HTUR_RS13660
uniprot id: D2RXB6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS15715
gene id: 543526:HTUR_RS15715
uniprot id: D2RZL6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13210
gene id: 543526:HTUR_RS13210
uniprot id: D2RWP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

543526:HTUR RS12865
gene id: 543526:HTUR_RS12865
uniprot id: D2RW51
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03555
gene id: 543526:HTUR_RS03555
uniprot id: D2RWZ8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

543526:HTUR RS10890
gene id: 543526:HTUR_RS10890
uniprot id: D2RTY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

543526:HTUR RS21620
gene id: 543526:HTUR_RS21620
uniprot id: D2S1I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS17225
gene id: 543526:HTUR_RS17225
uniprot id: D2RQI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

543526:HTUR RS07270
gene id: 543526:HTUR_RS07270
uniprot id: D2RQN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS16110
gene id: 543526:HTUR_RS16110
uniprot id: D2RPI4
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

543526:HTUR RS16485
gene id: 543526:HTUR_RS16485
uniprot id: D2RPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

543526:HTUR RS01490
gene id: 543526:HTUR_RS01490
uniprot id: D2RUR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS18170
gene id: 543526:HTUR_RS18170
uniprot id: D2RRT2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

543526:HTUR RS11800
gene id: 543526:HTUR_RS11800
uniprot id: D2RV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

543526:HTUR RS17360
gene id: 543526:HTUR_RS17360
uniprot id: D2RQZ5
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS15675
gene id: 543526:HTUR_RS15675
uniprot id: D2RZK7
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

543526:HTUR RS11090
gene id: 543526:HTUR_RS11090
uniprot id: D2RUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

543526:HTUR RS07150
gene id: 543526:HTUR_RS07150
uniprot id: D2RQL2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10975
gene id: 543526:HTUR_RS10975
uniprot id: D2RU04
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

543526:HTUR RS09920
gene id: 543526:HTUR_RS09920
uniprot id: D2RT18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

543526:HTUR RS01590
gene id: 543526:HTUR_RS01590
uniprot id: D2RUT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

543526:HTUR RS07660
gene id: 543526:HTUR_RS07660
uniprot id: D2RQW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS24160
gene id: 543526:HTUR_RS24160
uniprot id: D2S307
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

543526:HTUR RS16015
gene id: 543526:HTUR_RS16015
uniprot id: D2RZS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS21005
gene id: 543526:HTUR_RS21005
uniprot id: D2S162
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS15080
gene id: 543526:HTUR_RS15080
uniprot id: D2RYV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

543526:HTUR RS17980
gene id: 543526:HTUR_RS17980
uniprot id: D2RRP4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00140
gene id: 543526:HTUR_RS00140
uniprot id: D2RSV6
names: Similarity
messages: Belongs to the asparaginase 1 family.

543526:HTUR RS10985
gene id: 543526:HTUR_RS10985
uniprot id: D2RU06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS21190
gene id: 543526:HTUR_RS21190
uniprot id: D2S1A0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

543526:HTUR RS17000
gene id: 543526:HTUR_RS17000
uniprot id: D2RQE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

543526:HTUR RS18520
gene id: 543526:HTUR_RS18520
uniprot id: D2RS03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

543526:HTUR RS07680
gene id: 543526:HTUR_RS07680
uniprot id: D2RQX3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

543526:HTUR RS15505
gene id: 543526:HTUR_RS15505
uniprot id: D2RZH0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01750
gene id: 543526:HTUR_RS01750
uniprot id: D2RUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

543526:HTUR RS14550
gene id: 543526:HTUR_RS14550
uniprot id: D2RY69
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03130
gene id: 543526:HTUR_RS03130
uniprot id: D2RWD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS04330
gene id: 543526:HTUR_RS04330
uniprot id: D2RXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

543526:HTUR RS16005
gene id: 543526:HTUR_RS16005
uniprot id: D2RZS3
names: Similarity
messages: Belongs to the Ahb/Nir family.

543526:HTUR RS05845
gene id: 543526:HTUR_RS05845
uniprot id: D2RZE9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS14150
gene id: 543526:HTUR_RS14150
uniprot id: D2RXL0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08370
gene id: 543526:HTUR_RS08370
uniprot id: D2RRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

543526:HTUR RS16535
gene id: 543526:HTUR_RS16535
uniprot id: D2RPS0
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

543526:HTUR RS22015
gene id: 543526:HTUR_RS22015
uniprot id: D2S1R3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS16515
gene id: 543526:HTUR_RS16515
uniprot id: D2RPR6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

543526:HTUR RS14965
gene id: 543526:HTUR_RS14965
uniprot id: D2RYS9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

543526:HTUR RS11700
gene id: 543526:HTUR_RS11700
uniprot id: D2RV50
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

543526:HTUR RS20220
gene id: 543526:HTUR_RS20220
uniprot id: D2S0Q1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

543526:HTUR RS12705
gene id: 543526:HTUR_RS12705
uniprot id: D2RW18
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

543526:HTUR RS09390
gene id: 543526:HTUR_RS09390
uniprot id: D2RSL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS05310
gene id: 543526:HTUR_RS05310
uniprot id: D2RZ40
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS05095
gene id: 543526:HTUR_RS05095
uniprot id: D2RYM1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

543526:HTUR RS04725
gene id: 543526:HTUR_RS04725
uniprot id: D2RYE8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

543526:HTUR RS13730
gene id: 543526:HTUR_RS13730
uniprot id: D2RXD0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

543526:HTUR RS11110
gene id: 543526:HTUR_RS11110
uniprot id: D2RUG0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543526:HTUR RS00815
gene id: 543526:HTUR_RS00815
uniprot id: D2RTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

543526:HTUR RS12425
gene id: 543526:HTUR_RS12425
uniprot id: D2RVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS11035
gene id: 543526:HTUR_RS11035
uniprot id: D2RUE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

543526:HTUR RS10335
gene id: 543526:HTUR_RS10335
uniprot id: D2RTA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

543526:HTUR RS04155
gene id: 543526:HTUR_RS04155
uniprot id: D2RXP7
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

543526:HTUR RS08760
gene id: 543526:HTUR_RS08760
uniprot id: D2RS88
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Belongs to the isochorismate synthase family.

543526:HTUR RS22825
gene id: 543526:HTUR_RS22825
uniprot id: D2S282
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

543526:HTUR RS13875
gene id: 543526:HTUR_RS13875
uniprot id: D2RXF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

543526:HTUR RS00250
gene id: 543526:HTUR_RS00250
uniprot id: D2RTA9
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

543526:HTUR RS19340
gene id: 543526:HTUR_RS19340
uniprot id: D2S085
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

543526:HTUR RS12145
gene id: 543526:HTUR_RS12145
uniprot id: D2RVD8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

543526:HTUR RS13605
gene id: 543526:HTUR_RS13605
uniprot id: D2RXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

543526:HTUR RS05545
gene id: 543526:HTUR_RS05545
uniprot id: D2RZ89
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS22020
gene id: 543526:HTUR_RS22020
uniprot id: D2S1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS23030
gene id: 543526:HTUR_RS23030
uniprot id: D2S2C2
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

543526:HTUR RS12000
gene id: 543526:HTUR_RS12000
uniprot id: D2RVA8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00840
gene id: 543526:HTUR_RS00840
uniprot id: D2RTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

543526:HTUR RS17220
gene id: 543526:HTUR_RS17220
uniprot id: D2RQI6
names: Similarity
messages: Belongs to the UPF0146 family.

543526:HTUR RS13000
gene id: 543526:HTUR_RS13000
uniprot id: D2RWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

543526:HTUR RS10775
gene id: 543526:HTUR_RS10775
uniprot id: D2RTW7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07620
gene id: 543526:HTUR_RS07620
uniprot id: D2RQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

543526:HTUR RS04435
gene id: 543526:HTUR_RS04435
uniprot id: D2RXV6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

543526:HTUR RS12585
gene id: 543526:HTUR_RS12585
uniprot id: D2RVZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

543526:HTUR RS15825
gene id: 543526:HTUR_RS15825
uniprot id: D2RZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

543526:HTUR RS19320
gene id: 543526:HTUR_RS19320
uniprot id: D2S080
names: Similarity
messages: Belongs to the RutC family.

543526:HTUR RS05580
gene id: 543526:HTUR_RS05580
uniprot id: D2RZ96
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07765
gene id: 543526:HTUR_RS07765
uniprot id: D2RQY9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS25425
gene id: 543526:HTUR_RS25425
uniprot id: D2RXT0
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

543526:HTUR RS15930
gene id: 543526:HTUR_RS15930
uniprot id: D2RZQ8
names: Similarity
messages: Belongs to the HypE family.

543526:HTUR RS09360
gene id: 543526:HTUR_RS09360
uniprot id: D2RSL1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

543526:HTUR RS00660
gene id: 543526:HTUR_RS00660
uniprot id: D2RTJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS04245
gene id: 543526:HTUR_RS04245
uniprot id: D2RXR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

543526:HTUR RS24660
gene id: 543526:HTUR_RS24660
uniprot id: D2S3B3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

543526:HTUR RS17140
gene id: 543526:HTUR_RS17140
uniprot id: D2RQG9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

543526:HTUR RS18430
gene id: 543526:HTUR_RS18430
uniprot id: D2RRY5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS13170
gene id: 543526:HTUR_RS13170
uniprot id: D2RWP0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS12770
gene id: 543526:HTUR_RS12770
uniprot id: D2RW31
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

543526:HTUR RS14495
gene id: 543526:HTUR_RS14495
uniprot id: D2RY58
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS12540
gene id: 543526:HTUR_RS12540
uniprot id: D2RVY6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

543526:HTUR RS00075
gene id: 543526:HTUR_RS00075
uniprot id: D2RSU3
names: Similarity
messages: Belongs to the aspartokinase family.

543526:HTUR RS20570
gene id: 543526:HTUR_RS20570
uniprot id: D2S0X1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS17995
gene id: 543526:HTUR_RS17995
uniprot id: D2RRP7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

543526:HTUR RS13830
gene id: 543526:HTUR_RS13830
uniprot id: D2RXE7
names: Similarity
messages: Belongs to the cytochrome P450 family.

543526:HTUR RS11930
gene id: 543526:HTUR_RS11930
uniprot id: D2RV94
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS15765
gene id: 543526:HTUR_RS15765
uniprot id: D2RZM6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS23310
gene id: 543526:HTUR_RS23310
uniprot id: D2S2I2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08605
gene id: 543526:HTUR_RS08605
uniprot id: D2RS56
names: Similarity
messages: Belongs to the UPF0179 family.

543526:HTUR RS17335
gene id: 543526:HTUR_RS17335
uniprot id: D2RQZ0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07650
gene id: 543526:HTUR_RS07650
uniprot id: D2RQW6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10850
gene id: 543526:HTUR_RS10850
uniprot id: D2RTY2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

543526:HTUR RS15460
gene id: 543526:HTUR_RS15460
uniprot id: D2RZ31
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS21330
gene id: 543526:HTUR_RS21330
uniprot id: D2S1C6
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

543526:HTUR RS13350
gene id: 543526:HTUR_RS13350
uniprot id: D2RWS9
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

543526:HTUR RS19200
gene id: 543526:HTUR_RS19200
uniprot id: D2S056
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

543526:HTUR RS11980
gene id: 543526:HTUR_RS11980
uniprot id: D2RVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

543526:HTUR RS11040
gene id: 543526:HTUR_RS11040
uniprot id: D2RUE6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

543526:HTUR RS09395
gene id: 543526:HTUR_RS09395
uniprot id: D2RSL8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A 'suicide' enzyme that participates in biotin synthesis. Catalyzes the formation of (S)-8-amino-7-oxononanoate (DAN-carbamic acid) from (7R,8S)-8-amino-7-(carboxyamino)nonanoate (DAN), a function equivalent to the cannonical BioA reaction and the first half-reaction of BioD. The cellular requirement for biotin is thought be low enough that this single turnover enzyme supplies a sufficient amount of the cofactor. Overall it catalyzes three reactions: formation of a covalent linkage with 8-amino-7-oxononanoate to yield a BioU-DAN conjugate at the epsilon-amino group of Lys124 of BioU using NAD(P)H, carboxylation of the conjugate to form BioU-DAN-carbamic acid, and release of DAN-carbamic acid using NAD(P)+.
messages: Belongs to the BioU family.
messages: In cannonical biotin synthesis a pimeloyl-conjugate is transformed into biotin by the subsequent action of BioF, BioA, BioD and BioB. This enzyme replaces BioA and performs the first half-reaction of BioD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543526:HTUR RS16120
gene id: 543526:HTUR_RS16120
uniprot id: D2RPI6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS04410
gene id: 543526:HTUR_RS04410
uniprot id: D2RXV1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

543526:HTUR RS16955
gene id: 543526:HTUR_RS16955
uniprot id: D2RQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

543526:HTUR RS08625
gene id: 543526:HTUR_RS08625
uniprot id: D2RS60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

543526:HTUR RS00535
gene id: 543526:HTUR_RS00535
uniprot id: D2RTG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

543526:HTUR RS24470
gene id: 543526:HTUR_RS24470
uniprot id: D2S373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

543526:HTUR RS10515
gene id: 543526:HTUR_RS10515
uniprot id: D2RTR9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

543526:HTUR RS14015
gene id: 543526:HTUR_RS14015
uniprot id: D2RXI4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS07005
gene id: 543526:HTUR_RS07005
uniprot id: D2RQ58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543526:HTUR RS06470
gene id: 543526:HTUR_RS06470
uniprot id: D2RPH4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13890
gene id: 543526:HTUR_RS13890
uniprot id: D2RXF9
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

543526:HTUR RS03970
gene id: 543526:HTUR_RS03970
uniprot id: D2RX79
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

543526:HTUR RS04630
gene id: 543526:HTUR_RS04630
uniprot id: D2RXZ6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

543526:HTUR RS06635
gene id: 543526:HTUR_RS06635
uniprot id: D2RPY0
names: Similarity
messages: Belongs to the peptidase S49 family.

543526:HTUR RS09340
gene id: 543526:HTUR_RS09340
uniprot id: D2RSK7
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

543526:HTUR RS07425
gene id: 543526:HTUR_RS07425
uniprot id: D2RQR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

543526:HTUR RS06580
gene id: 543526:HTUR_RS06580
uniprot id: D2RPX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

543526:HTUR RS12545
gene id: 543526:HTUR_RS12545
uniprot id: D2RVY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS13995
gene id: 543526:HTUR_RS13995
uniprot id: D2RXI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS07215
gene id: 543526:HTUR_RS07215
uniprot id: D2RQM5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS18190
gene id: 543526:HTUR_RS18190
uniprot id: D2RRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

543526:HTUR RS12535
gene id: 543526:HTUR_RS12535
uniprot id: D2RVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

543526:HTUR RS21485
gene id: 543526:HTUR_RS21485
uniprot id: D2S1F7
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.

543526:HTUR RS01485
gene id: 543526:HTUR_RS01485
uniprot id: D2RUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

543526:HTUR RS07255
gene id: 543526:HTUR_RS07255
uniprot id: D2RQN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

543526:HTUR RS12890
gene id: 543526:HTUR_RS12890
uniprot id: D2RW57
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS04250
gene id: 543526:HTUR_RS04250
uniprot id: D2RXR7
names: Similarity
messages: Belongs to the TrpC family.

543526:HTUR RS06945
gene id: 543526:HTUR_RS06945
uniprot id: D2RQ45
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10945
gene id: 543526:HTUR_RS10945
uniprot id: D2RTZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS09415
gene id: 543526:HTUR_RS09415
uniprot id: D2RSM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

543526:HTUR RS19810
gene id: 543526:HTUR_RS19810
uniprot id: D2S0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

543526:HTUR RS22590
gene id: 543526:HTUR_RS22590
uniprot id: D2S243
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

543526:HTUR RS17920
gene id: 543526:HTUR_RS17920
uniprot id: D2RRA3
names: Similarity
messages: Belongs to the SUI1 family.

543526:HTUR RS12785
gene id: 543526:HTUR_RS12785
uniprot id: D2RW34
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

543526:HTUR RS09870
gene id: 543526:HTUR_RS09870
uniprot id: D2RT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

543526:HTUR RS15195
gene id: 543526:HTUR_RS15195
uniprot id: D2RYX4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01200
gene id: 543526:HTUR_RS01200
uniprot id: D2RU78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

543526:HTUR RS13490
gene id: 543526:HTUR_RS13490
uniprot id: D2RWV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

543526:HTUR RS02665
gene id: 543526:HTUR_RS02665
uniprot id: D2RVR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

543526:HTUR RS10995
gene id: 543526:HTUR_RS10995
uniprot id: D2RUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS17985
gene id: 543526:HTUR_RS17985
uniprot id: D2RRP5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

543526:HTUR RS00525
gene id: 543526:HTUR_RS00525
uniprot id: D2RTG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

543526:HTUR RS11045
gene id: 543526:HTUR_RS11045
uniprot id: D2RUE7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS17115
gene id: 543526:HTUR_RS17115
uniprot id: D2RQG4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS12240
gene id: 543526:HTUR_RS12240
uniprot id: D2RVF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS04255
gene id: 543526:HTUR_RS04255
uniprot id: D2RXR8
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

543526:HTUR RS14270
gene id: 543526:HTUR_RS14270
uniprot id: D2RY13
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543526:HTUR RS18775
gene id: 543526:HTUR_RS18775
uniprot id: D2RZX2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS18465
gene id: 543526:HTUR_RS18465
uniprot id: D2RRZ1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

543526:HTUR RS22975
gene id: 543526:HTUR_RS22975
uniprot id: D2S2B1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS11875
gene id: 543526:HTUR_RS11875
uniprot id: D2RV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS11640
gene id: 543526:HTUR_RS11640
uniprot id: D2RV38
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS01825
gene id: 543526:HTUR_RS01825
uniprot id: D2RUX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

543526:HTUR RS20520
gene id: 543526:HTUR_RS20520
uniprot id: D2S0W2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS06195
gene id: 543526:HTUR_RS06195
uniprot id: D2RPB3
names: Similarity
messages: Belongs to the UPF0045 family.

543526:HTUR RS01835
gene id: 543526:HTUR_RS01835
uniprot id: D2RUY1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS18060
gene id: 543526:HTUR_RS18060
uniprot id: D2RRR0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

543526:HTUR RS13670
gene id: 543526:HTUR_RS13670
uniprot id: D2RXB8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

543526:HTUR RS14800
gene id: 543526:HTUR_RS14800
uniprot id: D2RYB7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

543526:HTUR RS06925
gene id: 543526:HTUR_RS06925
uniprot id: D2RQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS00440
gene id: 543526:HTUR_RS00440
uniprot id: D2RTE5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS16985
gene id: 543526:HTUR_RS16985
uniprot id: D2RQD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

543526:HTUR RS00845
gene id: 543526:HTUR_RS00845
uniprot id: D2RTM9
names: Similarity
messages: Belongs to the Dps family.

543526:HTUR RS04515
gene id: 543526:HTUR_RS04515
uniprot id: D2RXX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

543526:HTUR RS14735
gene id: 543526:HTUR_RS14735
uniprot id: D2RYA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

543526:HTUR RS11175
gene id: 543526:HTUR_RS11175
uniprot id: D2RUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

543526:HTUR RS07695
gene id: 543526:HTUR_RS07695
uniprot id: D2RQX6
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

543526:HTUR RS07360
gene id: 543526:HTUR_RS07360
uniprot id: D2RQQ6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

543526:HTUR RS07480
gene id: 543526:HTUR_RS07480
uniprot id: D2RQT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

543526:HTUR RS08280
gene id: 543526:HTUR_RS08280
uniprot id: D2RRL3
names: Similarity
messages: Belongs to the GARS family.

543526:HTUR RS02800
gene id: 543526:HTUR_RS02800
uniprot id: D2RW66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

543526:HTUR RS05655
gene id: 543526:HTUR_RS05655
uniprot id: D2RZB1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS02635
gene id: 543526:HTUR_RS02635
uniprot id: D2RVQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS20095
gene id: 543526:HTUR_RS20095
uniprot id: D2S0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS24575
gene id: 543526:HTUR_RS24575
uniprot id: D2S394
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS20330
gene id: 543526:HTUR_RS20330
uniprot id: D2S0S4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

543526:HTUR RS24630
gene id: 543526:HTUR_RS24630
uniprot id: D2S3A6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS16410
gene id: 543526:HTUR_RS16410
uniprot id: D2RPP4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

543526:HTUR RS08115
gene id: 543526:HTUR_RS08115
uniprot id: D2RRH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS10215
gene id: 543526:HTUR_RS10215
uniprot id: D2RT79
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

543526:HTUR RS13105
gene id: 543526:HTUR_RS13105
uniprot id: D2RWM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

543526:HTUR RS19100
gene id: 543526:HTUR_RS19100
uniprot id: D2S036
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS11180
gene id: 543526:HTUR_RS11180
uniprot id: D2RUH4
names: Similarity
messages: Belongs to the arginase family.

543526:HTUR RS21915
gene id: 543526:HTUR_RS21915
uniprot id: D2S1P3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS12480
gene id: 543526:HTUR_RS12480
uniprot id: D2RVX4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

543526:HTUR RS09830
gene id: 543526:HTUR_RS09830
uniprot id: D2RSZ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

543526:HTUR RS17840
gene id: 543526:HTUR_RS17840
uniprot id: D2RR86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

543526:HTUR RS01110
gene id: 543526:HTUR_RS01110
uniprot id: D2RU59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS13140
gene id: 543526:HTUR_RS13140
uniprot id: D2RWN4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS14135
gene id: 543526:HTUR_RS14135
uniprot id: D2RXK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

543526:HTUR RS08990
gene id: 543526:HTUR_RS08990
uniprot id: D2RSD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

543526:HTUR RS12485
gene id: 543526:HTUR_RS12485
uniprot id: D2RVX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

543526:HTUR RS21100
gene id: 543526:HTUR_RS21100
uniprot id: D2S182
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS03560
gene id: 543526:HTUR_RS03560
uniprot id: D2RWZ9
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

543526:HTUR RS24135
gene id: 543526:HTUR_RS24135
uniprot id: D2S302
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

543526:HTUR RS14330
gene id: 543526:HTUR_RS14330
uniprot id: D2RY25
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS07655
gene id: 543526:HTUR_RS07655
uniprot id: D2RQW7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS19610
gene id: 543526:HTUR_RS19610
uniprot id: D2S0D5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

543526:HTUR RS07310
gene id: 543526:HTUR_RS07310
uniprot id: D2RQP4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

543526:HTUR RS13620
gene id: 543526:HTUR_RS13620
uniprot id: D2RXA8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

543526:HTUR RS01740
gene id: 543526:HTUR_RS01740
uniprot id: D2RUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS15525
gene id: 543526:HTUR_RS15525
uniprot id: D2RZH4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

543526:HTUR RS09295
gene id: 543526:HTUR_RS09295
uniprot id: D2RSJ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

543526:HTUR RS02520
gene id: 543526:HTUR_RS02520
uniprot id: D2RVN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS00595
gene id: 543526:HTUR_RS00595
uniprot id: D2RTH7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

543526:HTUR RS18305
gene id: 543526:HTUR_RS18305
uniprot id: D2RRW0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05815
gene id: 543526:HTUR_RS05815
uniprot id: D2RZE3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS18370
gene id: 543526:HTUR_RS18370
uniprot id: D2RRX3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

543526:HTUR RS11050
gene id: 543526:HTUR_RS11050
uniprot id: D2RUE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS07785
gene id: 543526:HTUR_RS07785
uniprot id: D2RRB4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS17150
gene id: 543526:HTUR_RS17150
uniprot id: D2RQH1
names: Similarity
messages: Belongs to the PDCD5 family.

543526:HTUR RS18110
gene id: 543526:HTUR_RS18110
uniprot id: D2RRS0
names: Similarity
messages: Belongs to the HMBS family.

543526:HTUR RS06920
gene id: 543526:HTUR_RS06920
uniprot id: D2RQ40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS16825
gene id: 543526:HTUR_RS16825
uniprot id: D2RQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

543526:HTUR RS04460
gene id: 543526:HTUR_RS04460
uniprot id: D2RXW1
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

543526:HTUR RS03715
gene id: 543526:HTUR_RS03715
uniprot id: D2RX30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

543526:HTUR RS06380
gene id: 543526:HTUR_RS06380
uniprot id: D2RPF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

543526:HTUR RS09620
gene id: 543526:HTUR_RS09620
uniprot id: D2RSR3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS11120
gene id: 543526:HTUR_RS11120
uniprot id: D2RUG2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08250
gene id: 543526:HTUR_RS08250
uniprot id: D2RRK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS13910
gene id: 543526:HTUR_RS13910
uniprot id: D2RXG3
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08895
gene id: 543526:HTUR_RS08895
uniprot id: D2RSB5
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS02075
gene id: 543526:HTUR_RS02075
uniprot id: D2RV27
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

543526:HTUR RS01585
gene id: 543526:HTUR_RS01585
uniprot id: D2RUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

543526:HTUR RS07550
gene id: 543526:HTUR_RS07550
uniprot id: D2RQU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

543526:HTUR RS21470
gene id: 543526:HTUR_RS21470
uniprot id: D2S1F4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS12075
gene id: 543526:HTUR_RS12075
uniprot id: D2RVC4
names: Similarity
messages: Belongs to the acylphosphatase family.

543526:HTUR RS05525
gene id: 543526:HTUR_RS05525
uniprot id: D2RZ85
names: Similarity
messages: Belongs to the complex I subunit 3 family.

543526:HTUR RS08755
gene id: 543526:HTUR_RS08755
uniprot id: D2RS87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

543526:HTUR RS02375
gene id: 543526:HTUR_RS02375
uniprot id: D2RVL2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

543526:HTUR RS13495
gene id: 543526:HTUR_RS13495
uniprot id: D2RWV8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

543526:HTUR RS10420
gene id: 543526:HTUR_RS10420
uniprot id: D2RTQ0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

543526:HTUR RS09565
gene id: 543526:HTUR_RS09565
uniprot id: D2RSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

543526:HTUR RS18410
gene id: 543526:HTUR_RS18410
uniprot id: D2RRY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

543526:HTUR RS00730
gene id: 543526:HTUR_RS00730
uniprot id: D2RTK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

543526:HTUR RS22845
gene id: 543526:HTUR_RS22845
uniprot id: D2S286
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

543526:HTUR RS14275
gene id: 543526:HTUR_RS14275
uniprot id: D2RY14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS18480
gene id: 543526:HTUR_RS18480
uniprot id: D2RRZ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

543526:HTUR RS22860
gene id: 543526:HTUR_RS22860
uniprot id: D2S289
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS04795
gene id: 543526:HTUR_RS04795
uniprot id: D2RYG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

543526:HTUR RS23150
gene id: 543526:HTUR_RS23150
uniprot id: D2S2E8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS00510
gene id: 543526:HTUR_RS00510
uniprot id: D2RTG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

543526:HTUR RS09350
gene id: 543526:HTUR_RS09350
uniprot id: D2RSK9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

543526:HTUR RS13270
gene id: 543526:HTUR_RS13270
uniprot id: D2RWQ9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS01005
gene id: 543526:HTUR_RS01005
uniprot id: D2RU38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

543526:HTUR RS03180
gene id: 543526:HTUR_RS03180
uniprot id: D2RWE2
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS17930
gene id: 543526:HTUR_RS17930
uniprot id: D2RRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

543526:HTUR RS22505
gene id: 543526:HTUR_RS22505
uniprot id: D2S225
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543526:HTUR RS13795
gene id: 543526:HTUR_RS13795
uniprot id: D2RXE3
names: Similarity
messages: Belongs to the peptidase S8 family.

543526:HTUR RS15260
gene id: 543526:HTUR_RS15260
uniprot id: D2RYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Membrane
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

543526:HTUR RS02565
gene id: 543526:HTUR_RS02565
uniprot id: D2RVP5
names: Similarity
messages: Belongs to the Ahb/Nir family.

543526:HTUR RS02090
gene id: 543526:HTUR_RS02090
uniprot id: D2RV30
names: Similarity
messages: Belongs to the MoaB/Mog family.

543526:HTUR RS16505
gene id: 543526:HTUR_RS16505
uniprot id: D2RPR4
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

543526:HTUR RS11185
gene id: 543526:HTUR_RS11185
uniprot id: D2RUH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS09045
gene id: 543526:HTUR_RS09045
uniprot id: D2RSE6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

543526:HTUR RS12170
gene id: 543526:HTUR_RS12170
uniprot id: D2RVE3
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

543526:HTUR RS14665
gene id: 543526:HTUR_RS14665
uniprot id: D2RY92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

543526:HTUR RS03380
gene id: 543526:HTUR_RS03380
uniprot id: D2RWI3
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13285
gene id: 543526:HTUR_RS13285
uniprot id: D2RWR2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

543526:HTUR RS11400
gene id: 543526:HTUR_RS11400
uniprot id: D2RUL8
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

543526:HTUR RS20465
gene id: 543526:HTUR_RS20465
uniprot id: D2S0V1
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.

543526:HTUR RS23515
gene id: 543526:HTUR_RS23515
uniprot id: D2S2M8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

543526:HTUR RS09900
gene id: 543526:HTUR_RS09900
uniprot id: D2RT13
names: Similarity
messages: Belongs to the peptidase C56 family.

543526:HTUR RS10720
gene id: 543526:HTUR_RS10720
uniprot id: D2RTV7
names: Similarity
messages: Belongs to the LarC family.

543526:HTUR RS20385
gene id: 543526:HTUR_RS20385
uniprot id: D2S0T5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543526:HTUR RS20610
gene id: 543526:HTUR_RS20610
uniprot id: D2S0X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543526:HTUR RS22920
gene id: 543526:HTUR_RS22920
uniprot id: D2S2A0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

543526:HTUR RS18105
gene id: 543526:HTUR_RS18105
uniprot id: D2RRR9
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

543526:HTUR RS04050
gene id: 543526:HTUR_RS04050
uniprot id: D2RXM5
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

543526:HTUR RS21880
gene id: 543526:HTUR_RS21880
uniprot id: D2S1N5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS01860
gene id: 543526:HTUR_RS01860
uniprot id: D2RUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

543526:HTUR RS09865
gene id: 543526:HTUR_RS09865
uniprot id: D2RT06
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

543526:HTUR RS01595
gene id: 543526:HTUR_RS01595
uniprot id: D2RUT3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS22970
gene id: 543526:HTUR_RS22970
uniprot id: D2S2B0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS19670
gene id: 543526:HTUR_RS19670
uniprot id: D2S0E6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS24750
gene id: 543526:HTUR_RS24750
uniprot id: D2S3D1
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

543526:HTUR RS11210
gene id: 543526:HTUR_RS11210
uniprot id: D2RUI0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

543526:HTUR RS18280
gene id: 543526:HTUR_RS18280
uniprot id: D2RRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

543526:HTUR RS07460
gene id: 543526:HTUR_RS07460
uniprot id: D2RQS6
names: Similarity
messages: Belongs to the BtpA family.

543526:HTUR RS22025
gene id: 543526:HTUR_RS22025
uniprot id: D2S1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS11940
gene id: 543526:HTUR_RS11940
uniprot id: D2RV96
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

543526:HTUR RS11280
gene id: 543526:HTUR_RS11280
uniprot id: D2RUJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

543526:HTUR RS20080
gene id: 543526:HTUR_RS20080
uniprot id: D2S0M6
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

543526:HTUR RS15855
gene id: 543526:HTUR_RS15855
uniprot id: D2RZP4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

543526:HTUR RS17350
gene id: 543526:HTUR_RS17350
uniprot id: D2RQZ3
names: Subcellular Location Annotation
messages: Cell membrane

543526:HTUR RS22340
gene id: 543526:HTUR_RS22340
uniprot id: D2S1Y2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS05415
gene id: 543526:HTUR_RS05415
uniprot id: D2RZ61
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

543526:HTUR RS10400
gene id: 543526:HTUR_RS10400
uniprot id: D2RTP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

543526:HTUR RS15885
gene id: 543526:HTUR_RS15885
uniprot id: D2RZP9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

543526:HTUR RS09575
gene id: 543526:HTUR_RS09575
uniprot id: D2RSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

543526:HTUR RS01900
gene id: 543526:HTUR_RS01900
uniprot id: D2RUZ4
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS10950
gene id: 543526:HTUR_RS10950
uniprot id: D2RTZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

543526:HTUR RS16495
gene id: 543526:HTUR_RS16495
uniprot id: D2RPR2
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

543526:HTUR RS13015
gene id: 543526:HTUR_RS13015
uniprot id: D2RWK9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

543526:HTUR RS23010
gene id: 543526:HTUR_RS23010
uniprot id: D2S2B8
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS08375
gene id: 543526:HTUR_RS08375
uniprot id: D2RRN2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

543526:HTUR RS05710
gene id: 543526:HTUR_RS05710
uniprot id: D2RZC1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

543526:HTUR RS06785
gene id: 543526:HTUR_RS06785
uniprot id: D2RQ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS12225
gene id: 543526:HTUR_RS12225
uniprot id: D2RVF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS04235
gene id: 543526:HTUR_RS04235
uniprot id: D2RXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

543526:HTUR RS00160
gene id: 543526:HTUR_RS00160
uniprot id: D2RSW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

543526:HTUR RS14960
gene id: 543526:HTUR_RS14960
uniprot id: D2RYS7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

543526:HTUR RS11055
gene id: 543526:HTUR_RS11055
uniprot id: D2RUE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

543526:HTUR RS02840
gene id: 543526:HTUR_RS02840
uniprot id: D2RW75
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS17905
gene id: 543526:HTUR_RS17905
uniprot id: D2RRA0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS09915
gene id: 543526:HTUR_RS09915
uniprot id: D2RT17
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

543526:HTUR RS05485
gene id: 543526:HTUR_RS05485
uniprot id: D2RZ77
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS23670
gene id: 543526:HTUR_RS23670
uniprot id: D2S2Q3
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS15560
gene id: 543526:HTUR_RS15560
uniprot id: D2RZI1
names: Similarity
messages: Belongs to the UPF0215 family.

543526:HTUR RS00915
gene id: 543526:HTUR_RS00915
uniprot id: D2RU17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

543526:HTUR RS08740
gene id: 543526:HTUR_RS08740
uniprot id: D2RS84
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS00240
gene id: 543526:HTUR_RS00240
uniprot id: D2RTA7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS24060
gene id: 543526:HTUR_RS24060
uniprot id: D2S2Y9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

543526:HTUR RS23005
gene id: 543526:HTUR_RS23005
uniprot id: D2S2B7
names: Similarity
messages: Belongs to the GcvT family.

543526:HTUR RS16295
gene id: 543526:HTUR_RS16295
uniprot id: D2RPM0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

543526:HTUR RS24360
gene id: 543526:HTUR_RS24360
uniprot id: D2S350
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

543526:HTUR RS02360
gene id: 543526:HTUR_RS02360
uniprot id: D2RVL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

543526:HTUR RS19185
gene id: 543526:HTUR_RS19185
uniprot id: D2S053
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

543526:HTUR RS24640
gene id: 543526:HTUR_RS24640
uniprot id: D2S3A9
names: Similarity
messages: Belongs to the SCO1/2 family.

543526:HTUR RS03250
gene id: 543526:HTUR_RS03250
uniprot id: D2RWF6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

543526:HTUR RS17175
gene id: 543526:HTUR_RS17175
uniprot id: D2RQH7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

543526:HTUR RS12040
gene id: 543526:HTUR_RS12040
uniprot id: D2RVB7
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

543526:HTUR RS11775
gene id: 543526:HTUR_RS11775
uniprot id: D2RV65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

543526:HTUR RS24325
gene id: 543526:HTUR_RS24325
uniprot id: D2S342
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS21385
gene id: 543526:HTUR_RS21385
uniprot id: D2S1D8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS15685
gene id: 543526:HTUR_RS15685
uniprot id: D2RZL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

543526:HTUR RS17970
gene id: 543526:HTUR_RS17970
uniprot id: D2RRP2
names: Similarity
messages: Belongs to the selenium-binding protein family.

543526:HTUR RS08855
gene id: 543526:HTUR_RS08855
uniprot id: D2RSA7
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

543526:HTUR RS03210
gene id: 543526:HTUR_RS03210
uniprot id: D2RWE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

543526:HTUR RS13740
gene id: 543526:HTUR_RS13740
uniprot id: D2RXD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS02480
gene id: 543526:HTUR_RS02480
uniprot id: D2RVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

543526:HTUR RS07760
gene id: 543526:HTUR_RS07760
uniprot id: D2RQY8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS06005
gene id: 543526:HTUR_RS06005
uniprot id: D2RP70
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS04455
gene id: 543526:HTUR_RS04455
uniprot id: D2RXW0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

543526:HTUR RS10235
gene id: 543526:HTUR_RS10235
uniprot id: D2RT83
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS02930
gene id: 543526:HTUR_RS02930
uniprot id: D2RW93
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

543526:HTUR RS13085
gene id: 543526:HTUR_RS13085
uniprot id: D2RWM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS16970
gene id: 543526:HTUR_RS16970
uniprot id: D2RQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

543526:HTUR RS03665
gene id: 543526:HTUR_RS03665
uniprot id: D2RX20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

543526:HTUR RS15340
gene id: 543526:HTUR_RS15340
uniprot id: D2RZ06
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

543526:HTUR RS03695
gene id: 543526:HTUR_RS03695
uniprot id: D2RX26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

543526:HTUR RS10405
gene id: 543526:HTUR_RS10405
uniprot id: D2RTP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS13555
gene id: 543526:HTUR_RS13555
uniprot id: D2RX96
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

543526:HTUR RS02540
gene id: 543526:HTUR_RS02540
uniprot id: D2RVP0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10255
gene id: 543526:HTUR_RS10255
uniprot id: D2RT87
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13095
gene id: 543526:HTUR_RS13095
uniprot id: D2RWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS02050
gene id: 543526:HTUR_RS02050
uniprot id: D2RV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

543526:HTUR RS13365
gene id: 543526:HTUR_RS13365
uniprot id: D2RWT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS21980
gene id: 543526:HTUR_RS21980
uniprot id: D2S1Q6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

543526:HTUR RS16045
gene id: 543526:HTUR_RS16045
uniprot id: D2RZT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

543526:HTUR RS14465
gene id: 543526:HTUR_RS14465
uniprot id: D2RY53
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS02725
gene id: 543526:HTUR_RS02725
uniprot id: D2RVS6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543526:HTUR RS00945
gene id: 543526:HTUR_RS00945
uniprot id: D2RU24
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

543526:HTUR RS14210
gene id: 543526:HTUR_RS14210
uniprot id: D2RY00
names: Similarity
messages: Belongs to the TPP enzyme family.

543526:HTUR RS04195
gene id: 543526:HTUR_RS04195
uniprot id: D2RXQ5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

543526:HTUR RS24310
gene id: 543526:HTUR_RS24310
uniprot id: D2S339
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS20305
gene id: 543526:HTUR_RS20305
uniprot id: D2S0R9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

543526:HTUR RS03945
gene id: 543526:HTUR_RS03945
uniprot id: D2RX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

543526:HTUR RS21955
gene id: 543526:HTUR_RS21955
uniprot id: D2S1Q1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10180
gene id: 543526:HTUR_RS10180
uniprot id: D2RT72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS12665
gene id: 543526:HTUR_RS12665
uniprot id: D2RW10
names: Similarity
messages: Belongs to the archease family.

543526:HTUR RS15870
gene id: 543526:HTUR_RS15870
uniprot id: D2RZP6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13055
gene id: 543526:HTUR_RS13055
uniprot id: D2RWL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

543526:HTUR RS18070
gene id: 543526:HTUR_RS18070
uniprot id: D2RRR2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

543526:HTUR RS10005
gene id: 543526:HTUR_RS10005
uniprot id: D2RT37
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

543526:HTUR RS01145
gene id: 543526:HTUR_RS01145
uniprot id: D2RU66
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

543526:HTUR RS24315
gene id: 543526:HTUR_RS24315
uniprot id: D2S340
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS11405
gene id: 543526:HTUR_RS11405
uniprot id: D2RUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

543526:HTUR RS10135
gene id: 543526:HTUR_RS10135
uniprot id: D2RT64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

543526:HTUR RS09180
gene id: 543526:HTUR_RS09180
uniprot id: D2RSH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

543526:HTUR RS06475
gene id: 543526:HTUR_RS06475
uniprot id: D2RPH5
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS22550
gene id: 543526:HTUR_RS22550
uniprot id: D2S236
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS05535
gene id: 543526:HTUR_RS05535
uniprot id: D2RZ87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS14340
gene id: 543526:HTUR_RS14340
uniprot id: D2RY27
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS18525
gene id: 543526:HTUR_RS18525
uniprot id: D2RS04
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07710
gene id: 543526:HTUR_RS07710
uniprot id: D2RQX9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS06535
gene id: 543526:HTUR_RS06535
uniprot id: D2RPW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

543526:HTUR RS15905
gene id: 543526:HTUR_RS15905
uniprot id: D2RZQ3
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08335
gene id: 543526:HTUR_RS08335
uniprot id: D2RRM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

543526:HTUR RS00325
gene id: 543526:HTUR_RS00325
uniprot id: D2RTC4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

543526:HTUR RS04355
gene id: 543526:HTUR_RS04355
uniprot id: D2RXU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS09605
gene id: 543526:HTUR_RS09605
uniprot id: D2RSR0
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

543526:HTUR RS17820
gene id: 543526:HTUR_RS17820
uniprot id: D2RR82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS12140
gene id: 543526:HTUR_RS12140
uniprot id: D2RVD7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

543526:HTUR RS07635
gene id: 543526:HTUR_RS07635
uniprot id: D2RQW3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

543526:HTUR RS00500
gene id: 543526:HTUR_RS00500
uniprot id: D2RTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

543526:HTUR RS16995
gene id: 543526:HTUR_RS16995
uniprot id: D2RQD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

543526:HTUR RS05105
gene id: 543526:HTUR_RS05105
uniprot id: D2RYM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS12575
gene id: 543526:HTUR_RS12575
uniprot id: D2RVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS18240
gene id: 543526:HTUR_RS18240
uniprot id: D2RRU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

543526:HTUR RS14655
gene id: 543526:HTUR_RS14655
uniprot id: D2RY90
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

543526:HTUR RS00065
gene id: 543526:HTUR_RS00065
uniprot id: D2RSU1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07980
gene id: 543526:HTUR_RS07980
uniprot id: D2RRF4
names: Similarity
messages: Belongs to the Dps family.

543526:HTUR RS10795
gene id: 543526:HTUR_RS10795
uniprot id: D2RTX1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

543526:HTUR RS24615
gene id: 543526:HTUR_RS24615
uniprot id: D2S3A3
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

543526:HTUR RS15760
gene id: 543526:HTUR_RS15760
uniprot id: D2RZM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS16550
gene id: 543526:HTUR_RS16550
uniprot id: D2RPS3
names: Similarity
messages: Belongs to the PdaD family.

543526:HTUR RS09320
gene id: 543526:HTUR_RS09320
uniprot id: D2RSK3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS05255
gene id: 543526:HTUR_RS05255
uniprot id: D2RYQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS03355
gene id: 543526:HTUR_RS03355
uniprot id: D2RWH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS07350
gene id: 543526:HTUR_RS07350
uniprot id: D2RQQ4
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

543526:HTUR RS20620
gene id: 543526:HTUR_RS20620
uniprot id: D2S0Y2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

543526:HTUR RS21875
gene id: 543526:HTUR_RS21875
uniprot id: D2S1N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

543526:HTUR RS10880
gene id: 543526:HTUR_RS10880
uniprot id: D2RTY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

543526:HTUR RS02775
gene id: 543526:HTUR_RS02775
uniprot id: D2RW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

543526:HTUR RS21505
gene id: 543526:HTUR_RS21505
uniprot id: D2S1G0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS12620
gene id: 543526:HTUR_RS12620
uniprot id: D2RW02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

543526:HTUR RS19350
gene id: 543526:HTUR_RS19350
uniprot id: D2S088
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

543526:HTUR RS12655
gene id: 543526:HTUR_RS12655
uniprot id: D2RW08
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

543526:HTUR RS13845
gene id: 543526:HTUR_RS13845
uniprot id: D2RXF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS14845
gene id: 543526:HTUR_RS14845
uniprot id: D2RYC6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

543526:HTUR RS16060
gene id: 543526:HTUR_RS16060
uniprot id: D2RZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

543526:HTUR RS21320
gene id: 543526:HTUR_RS21320
uniprot id: D2S1C4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS16425
gene id: 543526:HTUR_RS16425
uniprot id: D2RPP7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

543526:HTUR RS18270
gene id: 543526:HTUR_RS18270
uniprot id: D2RRV2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS14000
gene id: 543526:HTUR_RS14000
uniprot id: D2RXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

543526:HTUR RS19015
gene id: 543526:HTUR_RS19015
uniprot id: D2S019
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

543526:HTUR RS01620
gene id: 543526:HTUR_RS01620
uniprot id: D2RUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

543526:HTUR RS24735
gene id: 543526:HTUR_RS24735
uniprot id: D2S3C8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS08810
gene id: 543526:HTUR_RS08810
uniprot id: D2RS98
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS16190
gene id: 543526:HTUR_RS16190
uniprot id: D2RPJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS07380
gene id: 543526:HTUR_RS07380
uniprot id: D2RQR0
names: Similarity
messages: Belongs to the DtxR/MntR family.

543526:HTUR RS19890
gene id: 543526:HTUR_RS19890
uniprot id: D2S0I5
names: Similarity
messages: Belongs to the arginase family.

543526:HTUR RS04670
gene id: 543526:HTUR_RS04670
uniprot id: D2RYD7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS13335
gene id: 543526:HTUR_RS13335
uniprot id: D2RWS6
names: Subcellular Location Annotation
messages: Cell membrane

543526:HTUR RS09230
gene id: 543526:HTUR_RS09230
uniprot id: D2RSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

543526:HTUR RS21535
gene id: 543526:HTUR_RS21535
uniprot id: D2S1G6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

543526:HTUR RS00720
gene id: 543526:HTUR_RS00720
uniprot id: D2RTK3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS14990
gene id: 543526:HTUR_RS14990
uniprot id: D2RYT3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

543526:HTUR RS06615
gene id: 543526:HTUR_RS06615
uniprot id: D2RPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

543526:HTUR RS09095
gene id: 543526:HTUR_RS09095
uniprot id: D2RSG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS13245
gene id: 543526:HTUR_RS13245
uniprot id: D2RWQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS27675
gene id: 543526:HTUR_RS27675
uniprot id: D2S2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS13375
gene id: 543526:HTUR_RS13375
uniprot id: D2RWT4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS16610
gene id: 543526:HTUR_RS16610
uniprot id: D2RPT6
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

543526:HTUR RS17855
gene id: 543526:HTUR_RS17855
uniprot id: D2RR89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

543526:HTUR RS16490
gene id: 543526:HTUR_RS16490
uniprot id: D2RPR1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS14235
gene id: 543526:HTUR_RS14235
uniprot id: D2RY05
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543526:HTUR RS17200
gene id: 543526:HTUR_RS17200
uniprot id: D2RQI2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

543526:HTUR RS01610
gene id: 543526:HTUR_RS01610
uniprot id: D2RUT6
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

543526:HTUR RS01405
gene id: 543526:HTUR_RS01405
uniprot id: D2RUB9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

543526:HTUR RS12190
gene id: 543526:HTUR_RS12190
uniprot id: D2RVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

543526:HTUR RS08525
gene id: 543526:HTUR_RS08525
uniprot id: D2RS41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS15315
gene id: 543526:HTUR_RS15315
uniprot id: D2RZ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

543526:HTUR RS00800
gene id: 543526:HTUR_RS00800
uniprot id: D2RTM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

543526:HTUR RS10110
gene id: 543526:HTUR_RS10110
uniprot id: D2RT58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

543526:HTUR RS07520
gene id: 543526:HTUR_RS07520
uniprot id: D2RQT8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS00130
gene id: 543526:HTUR_RS00130
uniprot id: D2RSV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

543526:HTUR RS18540
gene id: 543526:HTUR_RS18540
uniprot id: D2RS07
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS06840
gene id: 543526:HTUR_RS06840
uniprot id: D2RQ22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

543526:HTUR RS01415
gene id: 543526:HTUR_RS01415
uniprot id: D2RUC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

543526:HTUR RS18880
gene id: 543526:HTUR_RS18880
uniprot id: D2RZZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

543526:HTUR RS11020
gene id: 543526:HTUR_RS11020
uniprot id: D2RUE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

543526:HTUR RS14325
gene id: 543526:HTUR_RS14325
uniprot id: D2RY24
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543526:HTUR RS23025
gene id: 543526:HTUR_RS23025
uniprot id: D2S2C1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

543526:HTUR RS04365
gene id: 543526:HTUR_RS04365
uniprot id: D2RXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS04170
gene id: 543526:HTUR_RS04170
uniprot id: D2RXQ0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS13980
gene id: 543526:HTUR_RS13980
uniprot id: D2RXH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

543526:HTUR RS24525
gene id: 543526:HTUR_RS24525
uniprot id: D2S384
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

543526:HTUR RS11215
gene id: 543526:HTUR_RS11215
uniprot id: D2RUI1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

543526:HTUR RS03580
gene id: 543526:HTUR_RS03580
uniprot id: D2RX04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

543526:HTUR RS02650
gene id: 543526:HTUR_RS02650
uniprot id: D2RVR1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

543526:HTUR RS01705
gene id: 543526:HTUR_RS01705
uniprot id: D2RUV5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

543526:HTUR RS23625
gene id: 543526:HTUR_RS23625
uniprot id: D2S2P5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

543526:HTUR RS10410
gene id: 543526:HTUR_RS10410
uniprot id: D2RTP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.

543526:HTUR RS02060
gene id: 543526:HTUR_RS02060
uniprot id: D2RV25
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

543526:HTUR RS23035
gene id: 543526:HTUR_RS23035
uniprot id: D2S2C4
names: Similarity
messages: Belongs to the RutC family.

543526:HTUR RS05645
gene id: 543526:HTUR_RS05645
uniprot id: D2RZA9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

543526:HTUR RS11705
gene id: 543526:HTUR_RS11705
uniprot id: D2RV51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

543526:HTUR RS22265
gene id: 543526:HTUR_RS22265
uniprot id: D2S1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS16895
gene id: 543526:HTUR_RS16895
uniprot id: D2RQB8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

543526:HTUR RS21325
gene id: 543526:HTUR_RS21325
uniprot id: D2S1C5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

543526:HTUR RS07300
gene id: 543526:HTUR_RS07300
uniprot id: D2RQP2
names: Similarity
messages: Belongs to the UPF0440 family.

543526:HTUR RS04380
gene id: 543526:HTUR_RS04380
uniprot id: D2RXU5
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

543526:HTUR RS09270
gene id: 543526:HTUR_RS09270
uniprot id: D2RSJ2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543526:HTUR RS04020
gene id: 543526:HTUR_RS04020
uniprot id: D2RX89
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

543526:HTUR RS04345
gene id: 543526:HTUR_RS04345
uniprot id: D2RXT8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS20300
gene id: 543526:HTUR_RS20300
uniprot id: D2S0R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

543526:HTUR RS05490
gene id: 543526:HTUR_RS05490
uniprot id: D2RZ78
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10270
gene id: 543526:HTUR_RS10270
uniprot id: D2RT90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

543526:HTUR RS08385
gene id: 543526:HTUR_RS08385
uniprot id: D2RRN4
names: Similarity
messages: Belongs to the FUN14 family.

543526:HTUR RS18725
gene id: 543526:HTUR_RS18725
uniprot id: D2RZW2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS08820
gene id: 543526:HTUR_RS08820
uniprot id: D2RSA0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS22650
gene id: 543526:HTUR_RS22650
uniprot id: D2S251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS01420
gene id: 543526:HTUR_RS01420
uniprot id: D2RUC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS11500
gene id: 543526:HTUR_RS11500
uniprot id: D2RUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS10460
gene id: 543526:HTUR_RS10460
uniprot id: D2RTQ8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

543526:HTUR RS15580
gene id: 543526:HTUR_RS15580
uniprot id: D2RZI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS04920
gene id: 543526:HTUR_RS04920
uniprot id: D2RYI7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

543526:HTUR RS09240
gene id: 543526:HTUR_RS09240
uniprot id: D2RSI6
names: Similarity
messages: Belongs to the manganese catalase family.

543526:HTUR RS20575
gene id: 543526:HTUR_RS20575
uniprot id: D2S0X2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS01625
gene id: 543526:HTUR_RS01625
uniprot id: D2RUT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS21940
gene id: 543526:HTUR_RS21940
uniprot id: D2S1P8
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

543526:HTUR RS12855
gene id: 543526:HTUR_RS12855
uniprot id: D2RW49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

543526:HTUR RS12765
gene id: 543526:HTUR_RS12765
uniprot id: D2RW30
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.

543526:HTUR RS10530
gene id: 543526:HTUR_RS10530
uniprot id: D2RTS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

543526:HTUR RS08390
gene id: 543526:HTUR_RS08390
uniprot id: D2RRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

543526:HTUR RS03860
gene id: 543526:HTUR_RS03860
uniprot id: D2RX58
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

543526:HTUR RS10980
gene id: 543526:HTUR_RS10980
uniprot id: D2RU05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

543526:HTUR RS23055
gene id: 543526:HTUR_RS23055
uniprot id: D2S2C7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS21255
gene id: 543526:HTUR_RS21255
uniprot id: D2S1B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS17865
gene id: 543526:HTUR_RS17865
uniprot id: D2RR91
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

543526:HTUR RS14630
gene id: 543526:HTUR_RS14630
uniprot id: D2RY85
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS12470
gene id: 543526:HTUR_RS12470
uniprot id: D2RVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

543526:HTUR RS03990
gene id: 543526:HTUR_RS03990
uniprot id: D2RX83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

543526:HTUR RS08545
gene id: 543526:HTUR_RS08545
uniprot id: D2RS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

543526:HTUR RS15555
gene id: 543526:HTUR_RS15555
uniprot id: D2RZI0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

543526:HTUR RS10190
gene id: 543526:HTUR_RS10190
uniprot id: D2RT74
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01500
gene id: 543526:HTUR_RS01500
uniprot id: D2RUR5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

543526:HTUR RS13800
gene id: 543526:HTUR_RS13800
uniprot id: D2RXE4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

543526:HTUR RS08360
gene id: 543526:HTUR_RS08360
uniprot id: D2RRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

543526:HTUR RS01150
gene id: 543526:HTUR_RS01150
uniprot id: D2RU67
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

543526:HTUR RS06930
gene id: 543526:HTUR_RS06930
uniprot id: D2RQ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS20435
gene id: 543526:HTUR_RS20435
uniprot id: D2S0U5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS15680
gene id: 543526:HTUR_RS15680
uniprot id: D2RZK9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03400
gene id: 543526:HTUR_RS03400
uniprot id: D2RWW6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

543526:HTUR RS16305
gene id: 543526:HTUR_RS16305
uniprot id: D2RPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

543526:HTUR RS06460
gene id: 543526:HTUR_RS06460
uniprot id: D2RPH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS07805
gene id: 543526:HTUR_RS07805
uniprot id: D2RRB8
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

543526:HTUR RS23935
gene id: 543526:HTUR_RS23935
uniprot id: D2S2W1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

543526:HTUR RS01985
gene id: 543526:HTUR_RS01985
uniprot id: D2RV11
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS11570
gene id: 543526:HTUR_RS11570
uniprot id: D2RUQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS10610
gene id: 543526:HTUR_RS10610
uniprot id: D2RTT6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS11000
gene id: 543526:HTUR_RS11000
uniprot id: D2RUD8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

543526:HTUR RS15550
gene id: 543526:HTUR_RS15550
uniprot id: D2RZH9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

543526:HTUR RS08565
gene id: 543526:HTUR_RS08565
uniprot id: D2RS49
names: Similarity
messages: Belongs to the UPF0047 family.

543526:HTUR RS08015
gene id: 543526:HTUR_RS08015
uniprot id: D2RRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

543526:HTUR RS01600
gene id: 543526:HTUR_RS01600
uniprot id: D2RUT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS24305
gene id: 543526:HTUR_RS24305
uniprot id: D2S338
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05475
gene id: 543526:HTUR_RS05475
uniprot id: D2RZ75
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS18325
gene id: 543526:HTUR_RS18325
uniprot id: D2RRW4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

543526:HTUR RS15240
gene id: 543526:HTUR_RS15240
uniprot id: D2RYY4
names: Subunit
messages: Homotrimer.

543526:HTUR RS07155
gene id: 543526:HTUR_RS07155
uniprot id: D2RQL3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

543526:HTUR RS22850
gene id: 543526:HTUR_RS22850
uniprot id: D2S287
names: Similarity
messages: Belongs to the GcvT family.

543526:HTUR RS17830
gene id: 543526:HTUR_RS17830
uniprot id: D2RR84
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

543526:HTUR RS00830
gene id: 543526:HTUR_RS00830
uniprot id: D2RTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

543526:HTUR RS17710
gene id: 543526:HTUR_RS17710
uniprot id: D2RR61
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

543526:HTUR RS02640
gene id: 543526:HTUR_RS02640
uniprot id: D2RVQ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS07445
gene id: 543526:HTUR_RS07445
uniprot id: D2RQS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

543526:HTUR RS14010
gene id: 543526:HTUR_RS14010
uniprot id: D2RXI3
names: Similarity
messages: Belongs to the UPF0284 family.

543526:HTUR RS02855
gene id: 543526:HTUR_RS02855
uniprot id: D2RW78
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

543526:HTUR RS11675
gene id: 543526:HTUR_RS11675
uniprot id: D2RV45
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

543526:HTUR RS17895
gene id: 543526:HTUR_RS17895
uniprot id: D2RR97
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

543526:HTUR RS22615
gene id: 543526:HTUR_RS22615
uniprot id: D2S245
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

543526:HTUR RS21780
gene id: 543526:HTUR_RS21780
uniprot id: D2S1L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS07810
gene id: 543526:HTUR_RS07810
uniprot id: D2RRB9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS19750
gene id: 543526:HTUR_RS19750
uniprot id: D2S0G3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS07580
gene id: 543526:HTUR_RS07580
uniprot id: D2RQV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS19825
gene id: 543526:HTUR_RS19825
uniprot id: D2S0H4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS09710
gene id: 543526:HTUR_RS09710
uniprot id: D2RSX6
names: Subcellular Location Annotation
messages: Cell membrane

543526:HTUR RS13255
gene id: 543526:HTUR_RS13255
uniprot id: D2RWQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

543526:HTUR RS19985
gene id: 543526:HTUR_RS19985
uniprot id: D2S0K5
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS23140
gene id: 543526:HTUR_RS23140
uniprot id: D2S2E6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

543526:HTUR RS11880
gene id: 543526:HTUR_RS11880
uniprot id: D2RV85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS11070
gene id: 543526:HTUR_RS11070
uniprot id: D2RUF2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS18675
gene id: 543526:HTUR_RS18675
uniprot id: D2RZV2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS00285
gene id: 543526:HTUR_RS00285
uniprot id: D2RTB6
names: Similarity
messages: Belongs to the peptidase S8 family.

543526:HTUR RS08060
gene id: 543526:HTUR_RS08060
uniprot id: D2RRG9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05320
gene id: 543526:HTUR_RS05320
uniprot id: D2RZ42
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

543526:HTUR RS01045
gene id: 543526:HTUR_RS01045
uniprot id: D2RU46
names: Similarity
messages: Belongs to the group II decarboxylase family.

543526:HTUR RS07995
gene id: 543526:HTUR_RS07995
uniprot id: D2RRF7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10825
gene id: 543526:HTUR_RS10825
uniprot id: D2RTX7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

543526:HTUR RS00330
gene id: 543526:HTUR_RS00330
uniprot id: D2RTC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

543526:HTUR RS02560
gene id: 543526:HTUR_RS02560
uniprot id: D2RVP4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS04110
gene id: 543526:HTUR_RS04110
uniprot id: D2RXN9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS04775
gene id: 543526:HTUR_RS04775
uniprot id: D2RYF8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

543526:HTUR RS04065
gene id: 543526:HTUR_RS04065
uniprot id: D2RXM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS07030
gene id: 543526:HTUR_RS07030
uniprot id: D2RQ63
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

543526:HTUR RS12455
gene id: 543526:HTUR_RS12455
uniprot id: D2RVW9
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

543526:HTUR RS11325
gene id: 543526:HTUR_RS11325
uniprot id: D2RUK2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS13500
gene id: 543526:HTUR_RS13500
uniprot id: D2RWV9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03885
gene id: 543526:HTUR_RS03885
uniprot id: D2RX63
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

543526:HTUR RS13765
gene id: 543526:HTUR_RS13765
uniprot id: D2RXD7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS17735
gene id: 543526:HTUR_RS17735
uniprot id: D2RR65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

543526:HTUR RS06865
gene id: 543526:HTUR_RS06865
uniprot id: D2RQ27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

543526:HTUR RS12210
gene id: 543526:HTUR_RS12210
uniprot id: D2RVF1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS00610
gene id: 543526:HTUR_RS00610
uniprot id: D2RTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS07715
gene id: 543526:HTUR_RS07715
uniprot id: D2RQY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

543526:HTUR RS12290
gene id: 543526:HTUR_RS12290
uniprot id: D2RVT7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

543526:HTUR RS15320
gene id: 543526:HTUR_RS15320
uniprot id: D2RZ01
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

543526:HTUR RS15300
gene id: 543526:HTUR_RS15300
uniprot id: D2RYZ7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

543526:HTUR RS07325
gene id: 543526:HTUR_RS07325
uniprot id: D2RQP9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

543526:HTUR RS03790
gene id: 543526:HTUR_RS03790
uniprot id: D2RX44
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS04000
gene id: 543526:HTUR_RS04000
uniprot id: D2RX85
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

543526:HTUR RS03285
gene id: 543526:HTUR_RS03285
uniprot id: D2RWG4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

543526:HTUR RS01190
gene id: 543526:HTUR_RS01190
uniprot id: D2RU76
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS11130
gene id: 543526:HTUR_RS11130
uniprot id: D2RUG4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

543526:HTUR RS09060
gene id: 543526:HTUR_RS09060
uniprot id: D2RSF4
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

543526:HTUR RS05905
gene id: 543526:HTUR_RS05905
uniprot id: D2RZG0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS15820
gene id: 543526:HTUR_RS15820
uniprot id: D2RZN7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

543526:HTUR RS18865
gene id: 543526:HTUR_RS18865
uniprot id: D2RZY8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

543526:HTUR RS18395
gene id: 543526:HTUR_RS18395
uniprot id: D2RRX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

543526:HTUR RS09100
gene id: 543526:HTUR_RS09100
uniprot id: D2RSG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS11560
gene id: 543526:HTUR_RS11560
uniprot id: D2RUQ1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS12095
gene id: 543526:HTUR_RS12095
uniprot id: D2RVC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

543526:HTUR RS04590
gene id: 543526:HTUR_RS04590
uniprot id: D2RXY7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS17145
gene id: 543526:HTUR_RS17145
uniprot id: D2RQH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS18755
gene id: 543526:HTUR_RS18755
uniprot id: D2RZW8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS03215
gene id: 543526:HTUR_RS03215
uniprot id: D2RWE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

543526:HTUR RS12605
gene id: 543526:HTUR_RS12605
uniprot id: D2RVZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

543526:HTUR RS14765
gene id: 543526:HTUR_RS14765
uniprot id: D2RYB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

543526:HTUR RS04820
gene id: 543526:HTUR_RS04820
uniprot id: D2RYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

543526:HTUR RS13050
gene id: 543526:HTUR_RS13050
uniprot id: D2RWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

543526:HTUR RS21840
gene id: 543526:HTUR_RS21840
uniprot id: D2S1M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS11205
gene id: 543526:HTUR_RS11205
uniprot id: D2RUH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

543526:HTUR RS21310
gene id: 543526:HTUR_RS21310
uniprot id: D2S1C2
names: Similarity
messages: Belongs to the peptidase S33 family.

543526:HTUR RS21360
gene id: 543526:HTUR_RS21360
uniprot id: D2S1D3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

543526:HTUR RS04555
gene id: 543526:HTUR_RS04555
uniprot id: D2RXX9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS23040
gene id: 543526:HTUR_RS23040
uniprot id: D2S2C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS03190
gene id: 543526:HTUR_RS03190
uniprot id: D2RWE4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10360
gene id: 543526:HTUR_RS10360
uniprot id: D2RTN7
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

543526:HTUR RS00785
gene id: 543526:HTUR_RS00785
uniprot id: D2RTL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

543526:HTUR RS11240
gene id: 543526:HTUR_RS11240
uniprot id: D2RUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS12735
gene id: 543526:HTUR_RS12735
uniprot id: D2RW24
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS11495
gene id: 543526:HTUR_RS11495
uniprot id: D2RUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS01700
gene id: 543526:HTUR_RS01700
uniprot id: D2RUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

543526:HTUR RS10105
gene id: 543526:HTUR_RS10105
uniprot id: D2RT57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

543526:HTUR RS19475
gene id: 543526:HTUR_RS19475
uniprot id: D2S0B2
names: Subcellular Location Annotation
messages: Nucleus

543526:HTUR RS14470
gene id: 543526:HTUR_RS14470
uniprot id: D2RY54
names: Similarity
messages: Belongs to the RutC family.

543526:HTUR RS18535
gene id: 543526:HTUR_RS18535
uniprot id: D2RS06
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS18710
gene id: 543526:HTUR_RS18710
uniprot id: D2RZV9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

543526:HTUR RS16945
gene id: 543526:HTUR_RS16945
uniprot id: D2RQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

543526:HTUR RS15835
gene id: 543526:HTUR_RS15835
uniprot id: D2RZP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

543526:HTUR RS10245
gene id: 543526:HTUR_RS10245
uniprot id: D2RT85
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS16420
gene id: 543526:HTUR_RS16420
uniprot id: D2RPP6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

543526:HTUR RS20775
gene id: 543526:HTUR_RS20775
uniprot id: D2S118
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05480
gene id: 543526:HTUR_RS05480
uniprot id: D2RZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

543526:HTUR RS21000
gene id: 543526:HTUR_RS21000
uniprot id: D2S161
names: Similarity
messages: Belongs to the NodU/CmcH family.

543526:HTUR RS08290
gene id: 543526:HTUR_RS08290
uniprot id: D2RRL5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS07625
gene id: 543526:HTUR_RS07625
uniprot id: D2RQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

543526:HTUR RS24435
gene id: 543526:HTUR_RS24435
uniprot id: D2S366
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

543526:HTUR RS23065
gene id: 543526:HTUR_RS23065
uniprot id: D2S2C9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS19345
gene id: 543526:HTUR_RS19345
uniprot id: D2S086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

543526:HTUR RS19430
gene id: 543526:HTUR_RS19430
uniprot id: D2S0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS04275
gene id: 543526:HTUR_RS04275
uniprot id: D2RXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

543526:HTUR RS15130
gene id: 543526:HTUR_RS15130
uniprot id: D2RYW1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08160
gene id: 543526:HTUR_RS08160
uniprot id: D2RRI9
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

543526:HTUR RS07500
gene id: 543526:HTUR_RS07500
uniprot id: D2RQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

543526:HTUR RS19145
gene id: 543526:HTUR_RS19145
uniprot id: D2S045
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS22925
gene id: 543526:HTUR_RS22925
uniprot id: D2S2A1
names: Similarity
messages: Belongs to the PEPCase type 1 family.

543526:HTUR RS08325
gene id: 543526:HTUR_RS08325
uniprot id: D2RRM2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12980
gene id: 543526:HTUR_RS12980
uniprot id: D2RWK2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS20370
gene id: 543526:HTUR_RS20370
uniprot id: D2S0T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS15720
gene id: 543526:HTUR_RS15720
uniprot id: D2RZL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

543526:HTUR RS08685
gene id: 543526:HTUR_RS08685
uniprot id: D2RS73
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

543526:HTUR RS24580
gene id: 543526:HTUR_RS24580
uniprot id: D2S396
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

543526:HTUR RS09585
gene id: 543526:HTUR_RS09585
uniprot id: D2RSQ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

543526:HTUR RS18375
gene id: 543526:HTUR_RS18375
uniprot id: D2RRX4
names: Similarity
messages: Belongs to the cytochrome P450 family.

543526:HTUR RS00555
gene id: 543526:HTUR_RS00555
uniprot id: D2RTG9
names: Similarity
messages: Belongs to the IMPACT family.

543526:HTUR RS14095
gene id: 543526:HTUR_RS14095
uniprot id: D2RXJ8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

543526:HTUR RS00620
gene id: 543526:HTUR_RS00620
uniprot id: D2RTI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS01455
gene id: 543526:HTUR_RS01455
uniprot id: D2RUC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

543526:HTUR RS07280
gene id: 543526:HTUR_RS07280
uniprot id: D2RQN8
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

543526:HTUR RS18470
gene id: 543526:HTUR_RS18470
uniprot id: D2RRZ2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

543526:HTUR RS21240
gene id: 543526:HTUR_RS21240
uniprot id: D2S1A8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00930
gene id: 543526:HTUR_RS00930
uniprot id: D2RU20
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

543526:HTUR RS13625
gene id: 543526:HTUR_RS13625
uniprot id: D2RXA9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

543526:HTUR RS04035
gene id: 543526:HTUR_RS04035
uniprot id: D2RXM1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS01360
gene id: 543526:HTUR_RS01360
uniprot id: D2RUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

543526:HTUR RS10380
gene id: 543526:HTUR_RS10380
uniprot id: D2RTP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

543526:HTUR RS04550
gene id: 543526:HTUR_RS04550
uniprot id: D2RXX8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS12720
gene id: 543526:HTUR_RS12720
uniprot id: D2RW21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

543526:HTUR RS20320
gene id: 543526:HTUR_RS20320
uniprot id: D2S0S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS06915
gene id: 543526:HTUR_RS06915
uniprot id: D2RQ39
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05025
gene id: 543526:HTUR_RS05025
uniprot id: D2RYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

543526:HTUR RS02145
gene id: 543526:HTUR_RS02145
uniprot id: D2RVG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

543526:HTUR RS21825
gene id: 543526:HTUR_RS21825
uniprot id: D2S1M3
names: Similarity
messages: Belongs to the TPP enzyme family.

543526:HTUR RS04685
gene id: 543526:HTUR_RS04685
uniprot id: D2RYE0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS21435
gene id: 543526:HTUR_RS21435
uniprot id: D2S1E8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS06015
gene id: 543526:HTUR_RS06015
uniprot id: D2RP72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS09755
gene id: 543526:HTUR_RS09755
uniprot id: D2RSY5
names: Similarity
messages: Belongs to the peptidase C56 family.

543526:HTUR RS15360
gene id: 543526:HTUR_RS15360
uniprot id: D2RZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

543526:HTUR RS12880
gene id: 543526:HTUR_RS12880
uniprot id: D2RW54
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS06725
gene id: 543526:HTUR_RS06725
uniprot id: D2RPZ8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00400
gene id: 543526:HTUR_RS00400
uniprot id: D2RTD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS15780
gene id: 543526:HTUR_RS15780
uniprot id: D2RZM9
names: Subcellular Location Annotation
messages: Nucleus

543526:HTUR RS02350
gene id: 543526:HTUR_RS02350
uniprot id: D2RVK8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS17950
gene id: 543526:HTUR_RS17950
uniprot id: D2RRA9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS20500
gene id: 543526:HTUR_RS20500
uniprot id: D2S0V8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS23430
gene id: 543526:HTUR_RS23430
uniprot id: D2S2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

543526:HTUR RS20150
gene id: 543526:HTUR_RS20150
uniprot id: D2S0P0
names: Similarity
messages: Belongs to the arginase family.

543526:HTUR RS19550
gene id: 543526:HTUR_RS19550
uniprot id: D2S0C5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

543526:HTUR RS12015
gene id: 543526:HTUR_RS12015
uniprot id: D2RVB1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS02845
gene id: 543526:HTUR_RS02845
uniprot id: D2RW76
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

543526:HTUR RS19870
gene id: 543526:HTUR_RS19870
uniprot id: D2S0I1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

543526:HTUR RS13135
gene id: 543526:HTUR_RS13135
uniprot id: D2RWN3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

543526:HTUR RS10990
gene id: 543526:HTUR_RS10990
uniprot id: D2RU07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

543526:HTUR RS13650
gene id: 543526:HTUR_RS13650
uniprot id: D2RXB4
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

543526:HTUR RS15640
gene id: 543526:HTUR_RS15640
uniprot id: D2RZK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

543526:HTUR RS18095
gene id: 543526:HTUR_RS18095
uniprot id: D2RRR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

543526:HTUR RS18460
gene id: 543526:HTUR_RS18460
uniprot id: D2RRZ0
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

543526:HTUR RS07780
gene id: 543526:HTUR_RS07780
uniprot id: D2RRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

543526:HTUR RS18955
gene id: 543526:HTUR_RS18955
uniprot id: D2S007
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS19965
gene id: 543526:HTUR_RS19965
uniprot id: D2S0K1
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS13195
gene id: 543526:HTUR_RS13195
uniprot id: D2RWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS06740
gene id: 543526:HTUR_RS06740
uniprot id: D2RQ01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

543526:HTUR RS11025
gene id: 543526:HTUR_RS11025
uniprot id: D2RUE3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

543526:HTUR RS11945
gene id: 543526:HTUR_RS11945
uniprot id: D2RV97
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS22655
gene id: 543526:HTUR_RS22655
uniprot id: D2S252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS04185
gene id: 543526:HTUR_RS04185
uniprot id: D2RXQ3
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08795
gene id: 543526:HTUR_RS08795
uniprot id: D2RS95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

543526:HTUR RS17230
gene id: 543526:HTUR_RS17230
uniprot id: D2RQI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS07970
gene id: 543526:HTUR_RS07970
uniprot id: D2RRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

543526:HTUR RS07630
gene id: 543526:HTUR_RS07630
uniprot id: D2RQW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

543526:HTUR RS01945
gene id: 543526:HTUR_RS01945
uniprot id: D2RV02
names: Similarity
messages: Belongs to the serpin family.

543526:HTUR RS01130
gene id: 543526:HTUR_RS01130
uniprot id: D2RU63
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

543526:HTUR RS01335
gene id: 543526:HTUR_RS01335
uniprot id: D2RUA4
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS21635
gene id: 543526:HTUR_RS21635
uniprot id: D2S1I7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS04980
gene id: 543526:HTUR_RS04980
uniprot id: D2RYK0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00825
gene id: 543526:HTUR_RS00825
uniprot id: D2RTM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

543526:HTUR RS01140
gene id: 543526:HTUR_RS01140
uniprot id: D2RU65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

543526:HTUR RS05305
gene id: 543526:HTUR_RS05305
uniprot id: D2RZ39
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01250
gene id: 543526:HTUR_RS01250
uniprot id: D2RU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

543526:HTUR RS02700
gene id: 543526:HTUR_RS02700
uniprot id: D2RVS1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

543526:HTUR RS06060
gene id: 543526:HTUR_RS06060
uniprot id: D2RP81
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS11870
gene id: 543526:HTUR_RS11870
uniprot id: D2RV83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS07420
gene id: 543526:HTUR_RS07420
uniprot id: D2RQR8
names: Similarity
messages: Belongs to the CutA family.

543526:HTUR RS21510
gene id: 543526:HTUR_RS21510
uniprot id: D2S1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS06595
gene id: 543526:HTUR_RS06595
uniprot id: D2RPX3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

543526:HTUR RS09875
gene id: 543526:HTUR_RS09875
uniprot id: D2RT08
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

543526:HTUR RS18205
gene id: 543526:HTUR_RS18205
uniprot id: D2RRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS14770
gene id: 543526:HTUR_RS14770
uniprot id: D2RYB1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS09910
gene id: 543526:HTUR_RS09910
uniprot id: D2RT15
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

543526:HTUR RS22235
gene id: 543526:HTUR_RS22235
uniprot id: D2S1V8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01990
gene id: 543526:HTUR_RS01990
uniprot id: D2RV12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS09795
gene id: 543526:HTUR_RS09795
uniprot id: D2RSZ3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

543526:HTUR RS08535
gene id: 543526:HTUR_RS08535
uniprot id: D2RS43
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00630
gene id: 543526:HTUR_RS00630
uniprot id: D2RTI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

543526:HTUR RS04315
gene id: 543526:HTUR_RS04315
uniprot id: D2RXT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS11005
gene id: 543526:HTUR_RS11005
uniprot id: D2RUD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

543526:HTUR RS20145
gene id: 543526:HTUR_RS20145
uniprot id: D2S0N9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS21965
gene id: 543526:HTUR_RS21965
uniprot id: D2S1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS17170
gene id: 543526:HTUR_RS17170
uniprot id: D2RQH6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13235
gene id: 543526:HTUR_RS13235
uniprot id: D2RWQ2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

543526:HTUR RS20885
gene id: 543526:HTUR_RS20885
uniprot id: D2S141
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08185
gene id: 543526:HTUR_RS08185
uniprot id: D2RRJ4
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

543526:HTUR RS24355
gene id: 543526:HTUR_RS24355
uniprot id: D2S349
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543526:HTUR RS19240
gene id: 543526:HTUR_RS19240
uniprot id: D2S064
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

543526:HTUR RS05930
gene id: 543526:HTUR_RS05930
uniprot id: D2RP55
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

543526:HTUR RS01855
gene id: 543526:HTUR_RS01855
uniprot id: D2RUY5
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS13840
gene id: 543526:HTUR_RS13840
uniprot id: D2RXE9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

543526:HTUR RS19880
gene id: 543526:HTUR_RS19880
uniprot id: D2S0I3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

543526:HTUR RS09845
gene id: 543526:HTUR_RS09845
uniprot id: D2RT02
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS01460
gene id: 543526:HTUR_RS01460
uniprot id: D2RUD0
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01815
gene id: 543526:HTUR_RS01815
uniprot id: D2RUX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543526:HTUR RS12555
gene id: 543526:HTUR_RS12555
uniprot id: D2RVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS00385
gene id: 543526:HTUR_RS00385
uniprot id: D2RTD5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543526:HTUR RS00850
gene id: 543526:HTUR_RS00850
uniprot id: D2RTN0
names: Similarity
messages: Belongs to the Dps family.

543526:HTUR RS21580
gene id: 543526:HTUR_RS21580
uniprot id: D2S1H6
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS17730
gene id: 543526:HTUR_RS17730
uniprot id: D2RR64
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS21245
gene id: 543526:HTUR_RS21245
uniprot id: D2S1A9
names: Similarity
messages: Belongs to the ferrochelatase family.

543526:HTUR RS20825
gene id: 543526:HTUR_RS20825
uniprot id: D2S128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS23980
gene id: 543526:HTUR_RS23980
uniprot id: D2S2W9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS20390
gene id: 543526:HTUR_RS20390
uniprot id: D2S0T6
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

543526:HTUR RS10895
gene id: 543526:HTUR_RS10895
uniprot id: D2RTZ0
names: Similarity
messages: Belongs to the UPF0045 family.

543526:HTUR RS11015
gene id: 543526:HTUR_RS11015
uniprot id: D2RUE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS13505
gene id: 543526:HTUR_RS13505
uniprot id: D2RWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

543526:HTUR RS03920
gene id: 543526:HTUR_RS03920
uniprot id: D2RX70
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

543526:HTUR RS11030
gene id: 543526:HTUR_RS11030
uniprot id: D2RUE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

543526:HTUR RS09020
gene id: 543526:HTUR_RS09020
uniprot id: D2RSE1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

543526:HTUR RS12550
gene id: 543526:HTUR_RS12550
uniprot id: D2RVY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

543526:HTUR RS07665
gene id: 543526:HTUR_RS07665
uniprot id: D2RQW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS03960
gene id: 543526:HTUR_RS03960
uniprot id: D2RX77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

543526:HTUR RS02125
gene id: 543526:HTUR_RS02125
uniprot id: D2RVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

543526:HTUR RS05165
gene id: 543526:HTUR_RS05165
uniprot id: D2RYN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

543526:HTUR RS24075
gene id: 543526:HTUR_RS24075
uniprot id: D2S2Z2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS08805
gene id: 543526:HTUR_RS08805
uniprot id: D2RS97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS10625
gene id: 543526:HTUR_RS10625
uniprot id: D2RTT9
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

543526:HTUR RS01030
gene id: 543526:HTUR_RS01030
uniprot id: D2RU43
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

543526:HTUR RS20395
gene id: 543526:HTUR_RS20395
uniprot id: D2S0T7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

543526:HTUR RS22010
gene id: 543526:HTUR_RS22010
uniprot id: D2S1R2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS18655
gene id: 543526:HTUR_RS18655
uniprot id: D2RZU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS10960
gene id: 543526:HTUR_RS10960
uniprot id: D2RU01
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

543526:HTUR RS14900
gene id: 543526:HTUR_RS14900
uniprot id: D2RYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

543526:HTUR RS12580
gene id: 543526:HTUR_RS12580
uniprot id: D2RVZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS17960
gene id: 543526:HTUR_RS17960
uniprot id: D2RRP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS22570
gene id: 543526:HTUR_RS22570
uniprot id: D2S239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS01395
gene id: 543526:HTUR_RS01395
uniprot id: D2RUB7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

543526:HTUR RS17565
gene id: 543526:HTUR_RS17565
uniprot id: D2RR37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

543526:HTUR RS21105
gene id: 543526:HTUR_RS21105
uniprot id: D2S183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

543526:HTUR RS20835
gene id: 543526:HTUR_RS20835
uniprot id: D2S130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS18055
gene id: 543526:HTUR_RS18055
uniprot id: D2RRQ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

543526:HTUR RS14745
gene id: 543526:HTUR_RS14745
uniprot id: D2RYA6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10535
gene id: 543526:HTUR_RS10535
uniprot id: D2RTS3
names: Similarity
messages: Belongs to the TrpF family.

543526:HTUR RS03940
gene id: 543526:HTUR_RS03940
uniprot id: D2RX74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS17390
gene id: 543526:HTUR_RS17390
uniprot id: D2RR01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

543526:HTUR RS20325
gene id: 543526:HTUR_RS20325
uniprot id: D2S0S3
names: Similarity
messages: Belongs to the RutC family.

543526:HTUR RS18845
gene id: 543526:HTUR_RS18845
uniprot id: D2RZY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Belongs to the inositol monophosphatase superfamily.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS04305
gene id: 543526:HTUR_RS04305
uniprot id: D2RXT1
names: Similarity
messages: Belongs to the eIF-2-alpha family.

543526:HTUR RS09355
gene id: 543526:HTUR_RS09355
uniprot id: D2RSL0
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

543526:HTUR RS14490
gene id: 543526:HTUR_RS14490
uniprot id: D2RY57
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS15330
gene id: 543526:HTUR_RS15330
uniprot id: D2RZ03
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

543526:HTUR RS10940
gene id: 543526:HTUR_RS10940
uniprot id: D2RTZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

543526:HTUR RS12235
gene id: 543526:HTUR_RS12235
uniprot id: D2RVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

543526:HTUR RS12650
gene id: 543526:HTUR_RS12650
uniprot id: D2RW07
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS21430
gene id: 543526:HTUR_RS21430
uniprot id: D2S1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

543526:HTUR RS12805
gene id: 543526:HTUR_RS12805
uniprot id: D2RW38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

543526:HTUR RS20955
gene id: 543526:HTUR_RS20955
uniprot id: D2S152
names: Similarity
messages: Belongs to the glutaredoxin family.

543526:HTUR RS05540
gene id: 543526:HTUR_RS05540
uniprot id: D2RZ88
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

543526:HTUR RS11650
gene id: 543526:HTUR_RS11650
uniprot id: D2RV40
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS20115
gene id: 543526:HTUR_RS20115
uniprot id: D2S0N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

543526:HTUR RS16270
gene id: 543526:HTUR_RS16270
uniprot id: D2RPL5
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS15350
gene id: 543526:HTUR_RS15350
uniprot id: D2RZ09
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS24085
gene id: 543526:HTUR_RS24085
uniprot id: D2S2Z3
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

543526:HTUR RS13100
gene id: 543526:HTUR_RS13100
uniprot id: D2RWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS05175
gene id: 543526:HTUR_RS05175
uniprot id: D2RYN7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS04535
gene id: 543526:HTUR_RS04535
uniprot id: D2RXX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS16235
gene id: 543526:HTUR_RS16235
uniprot id: D2RPK8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS15085
gene id: 543526:HTUR_RS15085
uniprot id: D2RYV3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS28055
gene id: 543526:HTUR_RS28055
uniprot id: D2RQD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS08715
gene id: 543526:HTUR_RS08715
uniprot id: D2RS79
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

543526:HTUR RS05790
gene id: 543526:HTUR_RS05790
uniprot id: D2RZD8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS06225
gene id: 543526:HTUR_RS06225
uniprot id: D2RPC1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS25630
gene id: 543526:HTUR_RS25630
uniprot id: D2RZI4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

543526:HTUR RS15000
gene id: 543526:HTUR_RS15000
uniprot id: D2RYT5
names: Similarity
messages: Belongs to the citrate synthase family.

543526:HTUR RS11955
gene id: 543526:HTUR_RS11955
uniprot id: D2RV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

543526:HTUR RS05510
gene id: 543526:HTUR_RS05510
uniprot id: D2RZ82
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05735
gene id: 543526:HTUR_RS05735
uniprot id: D2RZC6
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

543526:HTUR RS19840
gene id: 543526:HTUR_RS19840
uniprot id: D2S0H7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS05720
gene id: 543526:HTUR_RS05720
uniprot id: D2RZC3
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS03690
gene id: 543526:HTUR_RS03690
uniprot id: D2RX25
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

543526:HTUR RS12640
gene id: 543526:HTUR_RS12640
uniprot id: D2RW05
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS03655
gene id: 543526:HTUR_RS03655
uniprot id: D2RX19
names: Similarity
messages: Belongs to the TPP enzyme family.

543526:HTUR RS01660
gene id: 543526:HTUR_RS01660
uniprot id: D2RUU6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

543526:HTUR RS07275
gene id: 543526:HTUR_RS07275
uniprot id: D2RQN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS00855
gene id: 543526:HTUR_RS00855
uniprot id: D2RTN1
names: Similarity
messages: Belongs to the Dps family.

543526:HTUR RS01565
gene id: 543526:HTUR_RS01565
uniprot id: D2RUS7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

543526:HTUR RS22680
gene id: 543526:HTUR_RS22680
uniprot id: D2S257
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

543526:HTUR RS07015
gene id: 543526:HTUR_RS07015
uniprot id: D2RQ60
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543526:HTUR RS04280
gene id: 543526:HTUR_RS04280
uniprot id: D2RXS3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

543526:HTUR RS01160
gene id: 543526:HTUR_RS01160
uniprot id: D2RU70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

543526:HTUR RS11780
gene id: 543526:HTUR_RS11780
uniprot id: D2RV66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

543526:HTUR RS17765
gene id: 543526:HTUR_RS17765
uniprot id: D2RR71
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS21970
gene id: 543526:HTUR_RS21970
uniprot id: D2S1Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS01450
gene id: 543526:HTUR_RS01450
uniprot id: D2RUC8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS17990
gene id: 543526:HTUR_RS17990
uniprot id: D2RRP6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

543526:HTUR RS16890
gene id: 543526:HTUR_RS16890
uniprot id: D2RQB7
names: Similarity
messages: Belongs to the AAA ATPase family.

543526:HTUR RS20660
gene id: 543526:HTUR_RS20660
uniprot id: D2S0Y9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS13745
gene id: 543526:HTUR_RS13745
uniprot id: D2RXD3
names: Subunit
messages: Homotetramer.

543526:HTUR RS12870
gene id: 543526:HTUR_RS12870
uniprot id: D2RW52
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

543526:HTUR RS16320
gene id: 543526:HTUR_RS16320
uniprot id: D2RPM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

543526:HTUR RS12990
gene id: 543526:HTUR_RS12990
uniprot id: D2RWK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543526:HTUR RS00260
gene id: 543526:HTUR_RS00260
uniprot id: D2RTB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

543526:HTUR RS03045
gene id: 543526:HTUR_RS03045
uniprot id: D2RWB6
names: Similarity
messages: Belongs to the PspA/IM30 family.

543526:HTUR RS16580
gene id: 543526:HTUR_RS16580
uniprot id: D2RPS9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

543526:HTUR RS05155
gene id: 543526:HTUR_RS05155
uniprot id: D2RYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

543526:HTUR RS01270
gene id: 543526:HTUR_RS01270
uniprot id: D2RU92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

543526:HTUR RS18310
gene id: 543526:HTUR_RS18310
uniprot id: D2RRW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS13390
gene id: 543526:HTUR_RS13390
uniprot id: D2RWT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS12590
gene id: 543526:HTUR_RS12590
uniprot id: D2RVZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

543526:HTUR RS17280
gene id: 543526:HTUR_RS17280
uniprot id: D2RQJ8
names: Similarity
messages: Belongs to the NAD synthetase family.

543526:HTUR RS04310
gene id: 543526:HTUR_RS04310
uniprot id: D2RXT2
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

543526:HTUR RS21515
gene id: 543526:HTUR_RS21515
uniprot id: D2S1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS16365
gene id: 543526:HTUR_RS16365
uniprot id: D2RPN4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS06880
gene id: 543526:HTUR_RS06880
uniprot id: D2RQ30
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS14515
gene id: 543526:HTUR_RS14515
uniprot id: D2RY62
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543526:HTUR RS18405
gene id: 543526:HTUR_RS18405
uniprot id: D2RRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

543526:HTUR RS19950
gene id: 543526:HTUR_RS19950
uniprot id: D2S0J8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS08195
gene id: 543526:HTUR_RS08195
uniprot id: D2RRJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS00690
gene id: 543526:HTUR_RS00690
uniprot id: D2RTJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS17870
gene id: 543526:HTUR_RS17870
uniprot id: D2RR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

543526:HTUR RS02655
gene id: 543526:HTUR_RS02655
uniprot id: D2RVR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

543526:HTUR RS18935
gene id: 543526:HTUR_RS18935
uniprot id: D2S003
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS04160
gene id: 543526:HTUR_RS04160
uniprot id: D2RXP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

543526:HTUR RS10970
gene id: 543526:HTUR_RS10970
uniprot id: D2RU03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS19020
gene id: 543526:HTUR_RS19020
uniprot id: D2S020
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

543526:HTUR RS13385
gene id: 543526:HTUR_RS13385
uniprot id: D2RWT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS04370
gene id: 543526:HTUR_RS04370
uniprot id: D2RXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS17210
gene id: 543526:HTUR_RS17210
uniprot id: D2RQI4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS07770
gene id: 543526:HTUR_RS07770
uniprot id: D2RRB1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12895
gene id: 543526:HTUR_RS12895
uniprot id: D2RW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

543526:HTUR RS03280
gene id: 543526:HTUR_RS03280
uniprot id: D2RWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

543526:HTUR RS20105
gene id: 543526:HTUR_RS20105
uniprot id: D2S0N1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

543526:HTUR RS19010
gene id: 543526:HTUR_RS19010
uniprot id: D2S018
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

543526:HTUR RS06180
gene id: 543526:HTUR_RS06180
uniprot id: D2RPB0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS01295
gene id: 543526:HTUR_RS01295
uniprot id: D2RU97
names: Similarity
messages: Belongs to the UPF0201 family.

543526:HTUR RS13585
gene id: 543526:HTUR_RS13585
uniprot id: D2RXA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

543526:HTUR RS11330
gene id: 543526:HTUR_RS11330
uniprot id: D2RUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS12685
gene id: 543526:HTUR_RS12685
uniprot id: D2RW14
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

543526:HTUR RS04405
gene id: 543526:HTUR_RS04405
uniprot id: D2RXV0
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS05395
gene id: 543526:HTUR_RS05395
uniprot id: D2RZ57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

543526:HTUR RS14530
gene id: 543526:HTUR_RS14530
uniprot id: D2RY65
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

543526:HTUR RS12295
gene id: 543526:HTUR_RS12295
uniprot id: D2RVT8
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

543526:HTUR RS14540
gene id: 543526:HTUR_RS14540
uniprot id: D2RY67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

543526:HTUR RS12025
gene id: 543526:HTUR_RS12025
uniprot id: D2RVB4
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS01955
gene id: 543526:HTUR_RS01955
uniprot id: D2RV04
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543526:HTUR RS23070
gene id: 543526:HTUR_RS23070
uniprot id: D2S2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS14600
gene id: 543526:HTUR_RS14600
uniprot id: D2RY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

543526:HTUR RS19305
gene id: 543526:HTUR_RS19305
uniprot id: D2S077
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS08915
gene id: 543526:HTUR_RS08915
uniprot id: D2RSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS17510
gene id: 543526:HTUR_RS17510
uniprot id: D2RR26
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

543526:HTUR RS05765
gene id: 543526:HTUR_RS05765
uniprot id: D2RZD3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS24370
gene id: 543526:HTUR_RS24370
uniprot id: D2S352
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS15055
gene id: 543526:HTUR_RS15055
uniprot id: D2RYU7
names: Similarity
messages: Belongs to the HAM1 NTPase family.

543526:HTUR RS20340
gene id: 543526:HTUR_RS20340
uniprot id: D2S0S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

543526:HTUR RS13895
gene id: 543526:HTUR_RS13895
uniprot id: D2RXG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS01120
gene id: 543526:HTUR_RS01120
uniprot id: D2RU61
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08995
gene id: 543526:HTUR_RS08995
uniprot id: D2RSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

543526:HTUR RS24625
gene id: 543526:HTUR_RS24625
uniprot id: D2S3A5
names: Similarity
messages: Belongs to the peptidase M24B family.

543526:HTUR RS15635
gene id: 543526:HTUR_RS15635
uniprot id: D2RZJ9
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

543526:HTUR RS19455
gene id: 543526:HTUR_RS19455
uniprot id: D2S0A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Belongs to the inositol monophosphatase superfamily.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS20295
gene id: 543526:HTUR_RS20295
uniprot id: D2S0R7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

543526:HTUR RS07845
gene id: 543526:HTUR_RS07845
uniprot id: D2RRC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543526:HTUR RS01775
gene id: 543526:HTUR_RS01775
uniprot id: D2RUW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS06350
gene id: 543526:HTUR_RS06350
uniprot id: D2RPE9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

543526:HTUR RS10540
gene id: 543526:HTUR_RS10540
uniprot id: D2RTS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS11795
gene id: 543526:HTUR_RS11795
uniprot id: D2RV69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

543526:HTUR RS13345
gene id: 543526:HTUR_RS13345
uniprot id: D2RWS8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS02425
gene id: 543526:HTUR_RS02425
uniprot id: D2RVM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

543526:HTUR RS01730
gene id: 543526:HTUR_RS01730
uniprot id: D2RUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS09860
gene id: 543526:HTUR_RS09860
uniprot id: D2RT05
names: Similarity
messages: Belongs to the PrpD family.

543526:HTUR RS14675
gene id: 543526:HTUR_RS14675
uniprot id: D2RY94
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS02080
gene id: 543526:HTUR_RS02080
uniprot id: D2RV28
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

543526:HTUR RS08245
gene id: 543526:HTUR_RS08245
uniprot id: D2RRK6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

543526:HTUR RS17850
gene id: 543526:HTUR_RS17850
uniprot id: D2RR88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

543526:HTUR RS11125
gene id: 543526:HTUR_RS11125
uniprot id: D2RUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

543526:HTUR RS24225
gene id: 543526:HTUR_RS24225
uniprot id: D2S321
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03710
gene id: 543526:HTUR_RS03710
uniprot id: D2RX29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

543526:HTUR RS14160
gene id: 543526:HTUR_RS14160
uniprot id: D2RXL2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543526:HTUR RS01770
gene id: 543526:HTUR_RS01770
uniprot id: D2RUW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

543526:HTUR RS00755
gene id: 543526:HTUR_RS00755
uniprot id: D2RTL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

543526:HTUR RS01755
gene id: 543526:HTUR_RS01755
uniprot id: D2RUW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

543526:HTUR RS08705
gene id: 543526:HTUR_RS08705
uniprot id: D2RS77
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03745
gene id: 543526:HTUR_RS03745
uniprot id: D2RX36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

543526:HTUR RS15845
gene id: 543526:HTUR_RS15845
uniprot id: D2RZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

543526:HTUR RS12460
gene id: 543526:HTUR_RS12460
uniprot id: D2RVX0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

543526:HTUR RS19885
gene id: 543526:HTUR_RS19885
uniprot id: D2S0I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS22750
gene id: 543526:HTUR_RS22750
uniprot id: D2S267
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

543526:HTUR RS02085
gene id: 543526:HTUR_RS02085
uniprot id: D2RV29
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

543526:HTUR RS17525
gene id: 543526:HTUR_RS17525
uniprot id: D2RR29
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543526:HTUR RS15200
gene id: 543526:HTUR_RS15200
uniprot id: D2RYX5
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12610
gene id: 543526:HTUR_RS12610
uniprot id: D2RW00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS17315
gene id: 543526:HTUR_RS17315
uniprot id: D2RQK5
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12510
gene id: 543526:HTUR_RS12510
uniprot id: D2RVY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

543526:HTUR RS19730
gene id: 543526:HTUR_RS19730
uniprot id: D2S0F9
names: Subunit
messages: Homotrimer.

543526:HTUR RS03540
gene id: 543526:HTUR_RS03540
uniprot id: D2RWZ5
names: Similarity
messages: Belongs to the Dps family.

543526:HTUR RS00020
gene id: 543526:HTUR_RS00020
uniprot id: D2RST1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

543526:HTUR RS24235
gene id: 543526:HTUR_RS24235
uniprot id: D2S323
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

543526:HTUR RS07900
gene id: 543526:HTUR_RS07900
uniprot id: D2RRD6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS19295
gene id: 543526:HTUR_RS19295
uniprot id: D2S074
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS10600
gene id: 543526:HTUR_RS10600
uniprot id: D2RTT4
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS24425
gene id: 543526:HTUR_RS24425
uniprot id: D2S364
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

543526:HTUR RS07195
gene id: 543526:HTUR_RS07195
uniprot id: D2RQM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

543526:HTUR RS17610
gene id: 543526:HTUR_RS17610
uniprot id: D2RR46
names: Similarity
messages: Belongs to the SUI1 family.

543526:HTUR RS06495
gene id: 543526:HTUR_RS06495
uniprot id: D2RPH8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

543526:HTUR RS05515
gene id: 543526:HTUR_RS05515
uniprot id: D2RZ83
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

543526:HTUR RS10590
gene id: 543526:HTUR_RS10590
uniprot id: D2RTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

543526:HTUR RS00345
gene id: 543526:HTUR_RS00345
uniprot id: D2RTC8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

543526:HTUR RS05330
gene id: 543526:HTUR_RS05330
uniprot id: D2RZ44
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

543526:HTUR RS10260
gene id: 543526:HTUR_RS10260
uniprot id: D2RT88
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS10015
gene id: 543526:HTUR_RS10015
uniprot id: D2RT39
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS03430
gene id: 543526:HTUR_RS03430
uniprot id: D2RWX2
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS13065
gene id: 543526:HTUR_RS13065
uniprot id: D2RWL9
names: Similarity
messages: Belongs to the peptidase S1C family.

543526:HTUR RS08720
gene id: 543526:HTUR_RS08720
uniprot id: D2RS80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS18735
gene id: 543526:HTUR_RS18735
uniprot id: D2RZW4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543526:HTUR RS18210
gene id: 543526:HTUR_RS18210
uniprot id: D2RRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS14365
gene id: 543526:HTUR_RS14365
uniprot id: D2RY32
names: Similarity
messages: Belongs to the HypE family.

543526:HTUR RS15385
gene id: 543526:HTUR_RS15385
uniprot id: D2RZ16
names: Similarity
messages: Belongs to the peptidase C59 family.

543526:HTUR RS21830
gene id: 543526:HTUR_RS21830
uniprot id: D2S1M4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

543526:HTUR RS03350
gene id: 543526:HTUR_RS03350
uniprot id: D2RWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS02660
gene id: 543526:HTUR_RS02660
uniprot id: D2RVR3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

543526:HTUR RS11925
gene id: 543526:HTUR_RS11925
uniprot id: D2RV93
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS16775
gene id: 543526:HTUR_RS16775
uniprot id: D2RQ93
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

543526:HTUR RS16830
gene id: 543526:HTUR_RS16830
uniprot id: D2RQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

543526:HTUR RS04270
gene id: 543526:HTUR_RS04270
uniprot id: D2RXS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543526:HTUR RS11480
gene id: 543526:HTUR_RS11480
uniprot id: D2RUN6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543526:HTUR RS01670
gene id: 543526:HTUR_RS01670
uniprot id: D2RUU8
names: Similarity
messages: Belongs to the HerA family.

543526:HTUR RS10955
gene id: 543526:HTUR_RS10955
uniprot id: D2RU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

543526:HTUR RS19620
gene id: 543526:HTUR_RS19620
uniprot id: D2S0D7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS11725
gene id: 543526:HTUR_RS11725
uniprot id: D2RV55
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS10440
gene id: 543526:HTUR_RS10440
uniprot id: D2RTQ4
names: Similarity
messages: Belongs to the Nth/MutY family.

543526:HTUR RS15090
gene id: 543526:HTUR_RS15090
uniprot id: D2RYV4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

543526:HTUR RS07135
gene id: 543526:HTUR_RS07135
uniprot id: D2RQK9
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS23075
gene id: 543526:HTUR_RS23075
uniprot id: D2S2D1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS01760
gene id: 543526:HTUR_RS01760
uniprot id: D2RUW4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS17035
gene id: 543526:HTUR_RS17035
uniprot id: D2RQE7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

543526:HTUR RS08235
gene id: 543526:HTUR_RS08235
uniprot id: D2RRK4
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

543526:HTUR RS08380
gene id: 543526:HTUR_RS08380
uniprot id: D2RRN3
names: Similarity
messages: Belongs to the SDO1/SBDS family.

543526:HTUR RS11275
gene id: 543526:HTUR_RS11275
uniprot id: D2RUJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

543526:HTUR RS13440
gene id: 543526:HTUR_RS13440
uniprot id: D2RWU6
names: Similarity
messages: Belongs to the UPF0173 family.

543526:HTUR RS19450
gene id: 543526:HTUR_RS19450
uniprot id: D2S0A7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

543526:HTUR RS05695
gene id: 543526:HTUR_RS05695
uniprot id: D2RZB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS05530
gene id: 543526:HTUR_RS05530
uniprot id: D2RZ86
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

543526:HTUR RS10965
gene id: 543526:HTUR_RS10965
uniprot id: D2RU02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

543526:HTUR RS02180
gene id: 543526:HTUR_RS02180
uniprot id: D2RVH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS17815
gene id: 543526:HTUR_RS17815
uniprot id: D2RR81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

543526:HTUR RS23045
gene id: 543526:HTUR_RS23045
uniprot id: D2S2C6
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS17165
gene id: 543526:HTUR_RS17165
uniprot id: D2RQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

543526:HTUR RS00670
gene id: 543526:HTUR_RS00670
uniprot id: D2RTJ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

543526:HTUR RS18885
gene id: 543526:HTUR_RS18885
uniprot id: D2RZZ2
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.

543526:HTUR RS00695
gene id: 543526:HTUR_RS00695
uniprot id: D2RTJ8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07440
gene id: 543526:HTUR_RS07440
uniprot id: D2RQS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

543526:HTUR RS13075
gene id: 543526:HTUR_RS13075
uniprot id: D2RWM1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

543526:HTUR RS17400
gene id: 543526:HTUR_RS17400
uniprot id: D2RR04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543526:HTUR RS05070
gene id: 543526:HTUR_RS05070
uniprot id: D2RYL6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

543526:HTUR RS07450
gene id: 543526:HTUR_RS07450
uniprot id: D2RQS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

543526:HTUR RS22640
gene id: 543526:HTUR_RS22640
uniprot id: D2S249
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS00520
gene id: 543526:HTUR_RS00520
uniprot id: D2RTG2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS15135
gene id: 543526:HTUR_RS15135
uniprot id: D2RYW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS07860
gene id: 543526:HTUR_RS07860
uniprot id: D2RRC8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS07405
gene id: 543526:HTUR_RS07405
uniprot id: D2RQR5
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

543526:HTUR RS02405
gene id: 543526:HTUR_RS02405
uniprot id: D2RVL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS20065
gene id: 543526:HTUR_RS20065
uniprot id: D2S0M3
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

543526:HTUR RS01525
gene id: 543526:HTUR_RS01525
uniprot id: D2RUR9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

543526:HTUR RS24530
gene id: 543526:HTUR_RS24530
uniprot id: D2S385
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS06995
gene id: 543526:HTUR_RS06995
uniprot id: D2RQ56
names: Similarity
messages: Belongs to the peptidase M24B family.

543526:HTUR RS13780
gene id: 543526:HTUR_RS13780
uniprot id: D2RXE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

543526:HTUR RS01115
gene id: 543526:HTUR_RS01115
uniprot id: D2RU60
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00985
gene id: 543526:HTUR_RS00985
uniprot id: D2RU34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

543526:HTUR RS02810
gene id: 543526:HTUR_RS02810
uniprot id: D2RW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

543526:HTUR RS14280
gene id: 543526:HTUR_RS14280
uniprot id: D2RY15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS09225
gene id: 543526:HTUR_RS09225
uniprot id: D2RSI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

543526:HTUR RS04975
gene id: 543526:HTUR_RS04975
uniprot id: D2RYJ9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

543526:HTUR RS14730
gene id: 543526:HTUR_RS14730
uniprot id: D2RYA4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS00450
gene id: 543526:HTUR_RS00450
uniprot id: D2RTE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

543526:HTUR RS03220
gene id: 543526:HTUR_RS03220
uniprot id: D2RWF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

543526:HTUR RS15995
gene id: 543526:HTUR_RS15995
uniprot id: D2RZS1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

543526:HTUR RS08900
gene id: 543526:HTUR_RS08900
uniprot id: D2RSB6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

543526:HTUR RS10230
gene id: 543526:HTUR_RS10230
uniprot id: D2RT82
names: Function
messages: Part of a potassium transport system.

543526:HTUR RS05900
gene id: 543526:HTUR_RS05900
uniprot id: D2RZF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS17040
gene id: 543526:HTUR_RS17040
uniprot id: D2RQE8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

543526:HTUR RS07315
gene id: 543526:HTUR_RS07315
uniprot id: D2RQP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

543526:HTUR RS11200
gene id: 543526:HTUR_RS11200
uniprot id: D2RUH8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

543526:HTUR RS01390
gene id: 543526:HTUR_RS01390
uniprot id: D2RUB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

543526:HTUR RS16210
gene id: 543526:HTUR_RS16210
uniprot id: D2RPK3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

543526:HTUR RS18350
gene id: 543526:HTUR_RS18350
uniprot id: D2RRW9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS24535
gene id: 543526:HTUR_RS24535
uniprot id: D2S386
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

543526:HTUR RS18770
gene id: 543526:HTUR_RS18770
uniprot id: D2RZX1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS11975
gene id: 543526:HTUR_RS11975
uniprot id: D2RVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

543526:HTUR RS13750
gene id: 543526:HTUR_RS13750
uniprot id: D2RXD4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS09890
gene id: 543526:HTUR_RS09890
uniprot id: D2RT11
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00765
gene id: 543526:HTUR_RS00765
uniprot id: D2RTL3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS06745
gene id: 543526:HTUR_RS06745
uniprot id: D2RQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

543526:HTUR RS14910
gene id: 543526:HTUR_RS14910
uniprot id: D2RYR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS11095
gene id: 543526:HTUR_RS11095
uniprot id: D2RUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

543526:HTUR RS15325
gene id: 543526:HTUR_RS15325
uniprot id: D2RZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

543526:HTUR RS06835
gene id: 543526:HTUR_RS06835
uniprot id: D2RQ21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS07175
gene id: 543526:HTUR_RS07175
uniprot id: D2RQL7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS18850
gene id: 543526:HTUR_RS18850
uniprot id: D2RZY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS12595
gene id: 543526:HTUR_RS12595
uniprot id: D2RVZ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

543526:HTUR RS09405
gene id: 543526:HTUR_RS09405
uniprot id: D2RSM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS09105
gene id: 543526:HTUR_RS09105
uniprot id: D2RSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS10865
gene id: 543526:HTUR_RS10865
uniprot id: D2RTY5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

543526:HTUR RS07295
gene id: 543526:HTUR_RS07295
uniprot id: D2RQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

543526:HTUR RS01550
gene id: 543526:HTUR_RS01550
uniprot id: D2RUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

543526:HTUR RS01605
gene id: 543526:HTUR_RS01605
uniprot id: D2RUT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS21845
gene id: 543526:HTUR_RS21845
uniprot id: D2S1M7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS01425
gene id: 543526:HTUR_RS01425
uniprot id: D2RUC3
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12365
gene id: 543526:HTUR_RS12365
uniprot id: D2RVV2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS17445
gene id: 543526:HTUR_RS17445
uniprot id: D2RR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

543526:HTUR RS12660
gene id: 543526:HTUR_RS12660
uniprot id: D2RW09
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01800
gene id: 543526:HTUR_RS01800
uniprot id: D2RUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

543526:HTUR RS16675
gene id: 543526:HTUR_RS16675
uniprot id: D2RPU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

543526:HTUR RS17425
gene id: 543526:HTUR_RS17425
uniprot id: D2RR09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

543526:HTUR RS12675
gene id: 543526:HTUR_RS12675
uniprot id: D2RW12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

543526:HTUR RS12160
gene id: 543526:HTUR_RS12160
uniprot id: D2RVE1
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

543526:HTUR RS18050
gene id: 543526:HTUR_RS18050
uniprot id: D2RRQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

543526:HTUR RS21850
gene id: 543526:HTUR_RS21850
uniprot id: D2S1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS18900
gene id: 543526:HTUR_RS18900
uniprot id: D2RZZ6
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS13645
gene id: 543526:HTUR_RS13645
uniprot id: D2RXB3
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

543526:HTUR RS23520
gene id: 543526:HTUR_RS23520
uniprot id: D2S2M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

543526:HTUR RS19025
gene id: 543526:HTUR_RS19025
uniprot id: D2S021
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

543526:HTUR RS18340
gene id: 543526:HTUR_RS18340
uniprot id: D2RRW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

543526:HTUR RS10780
gene id: 543526:HTUR_RS10780
uniprot id: D2RTW8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS15625
gene id: 543526:HTUR_RS15625
uniprot id: D2RZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

543526:HTUR RS19975
gene id: 543526:HTUR_RS19975
uniprot id: D2S0K3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS12615
gene id: 543526:HTUR_RS12615
uniprot id: D2RW01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

543526:HTUR RS08975
gene id: 543526:HTUR_RS08975
uniprot id: D2RSD1
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS09120
gene id: 543526:HTUR_RS09120
uniprot id: D2RSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

543526:HTUR RS17535
gene id: 543526:HTUR_RS17535
uniprot id: D2RR31
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

543526:HTUR RS17705
gene id: 543526:HTUR_RS17705
uniprot id: D2RR60
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

543526:HTUR RS15985
gene id: 543526:HTUR_RS15985
uniprot id: D2RZR9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

543526:HTUR RS07395
gene id: 543526:HTUR_RS07395
uniprot id: D2RQR3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

543526:HTUR RS04745
gene id: 543526:HTUR_RS04745
uniprot id: D2RYF2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

543526:HTUR RS09050
gene id: 543526:HTUR_RS09050
uniprot id: D2RSF2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS12055
gene id: 543526:HTUR_RS12055
uniprot id: D2RVC0
names: Similarity
messages: Belongs to the UPF0212 family.

543526:HTUR RS14625
gene id: 543526:HTUR_RS14625
uniprot id: D2RY84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

543526:HTUR RS22855
gene id: 543526:HTUR_RS22855
uniprot id: D2S288
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

543526:HTUR RS01205
gene id: 543526:HTUR_RS01205
uniprot id: D2RU79
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

543526:HTUR RS07235
gene id: 543526:HTUR_RS07235
uniprot id: D2RQM9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

543526:HTUR RS17415
gene id: 543526:HTUR_RS17415
uniprot id: D2RR07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

543526:HTUR RS07330
gene id: 543526:HTUR_RS07330
uniprot id: D2RQQ0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

543526:HTUR RS03965
gene id: 543526:HTUR_RS03965
uniprot id: D2RX78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

543526:HTUR RS18760
gene id: 543526:HTUR_RS18760
uniprot id: D2RZW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS18035
gene id: 543526:HTUR_RS18035
uniprot id: D2RRQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS00925
gene id: 543526:HTUR_RS00925
uniprot id: D2RU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

543526:HTUR RS00810
gene id: 543526:HTUR_RS00810
uniprot id: D2RTM2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

543526:HTUR RS04360
gene id: 543526:HTUR_RS04360
uniprot id: D2RXU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS14980
gene id: 543526:HTUR_RS14980
uniprot id: D2RYT1
names: Similarity
messages: Belongs to the RutC family.

543526:HTUR RS02865
gene id: 543526:HTUR_RS02865
uniprot id: D2RW80
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

543526:HTUR RS21560
gene id: 543526:HTUR_RS21560
uniprot id: D2S1H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

543526:HTUR RS10660
gene id: 543526:HTUR_RS10660
uniprot id: D2RTU5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

543526:HTUR RS20710
gene id: 543526:HTUR_RS20710
uniprot id: D2S102
names: Similarity
messages: Belongs to the selenium-binding protein family.

543526:HTUR RS11505
gene id: 543526:HTUR_RS11505
uniprot id: D2RUP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS12420
gene id: 543526:HTUR_RS12420
uniprot id: D2RVW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS22275
gene id: 543526:HTUR_RS22275
uniprot id: D2S1W7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS22910
gene id: 543526:HTUR_RS22910
uniprot id: D2S298
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS11470
gene id: 543526:HTUR_RS11470
uniprot id: D2RUN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS23110
gene id: 543526:HTUR_RS23110
uniprot id: D2S2D8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543526:HTUR RS00280
gene id: 543526:HTUR_RS00280
uniprot id: D2RTB5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

543526:HTUR RS16500
gene id: 543526:HTUR_RS16500
uniprot id: D2RPR3
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

543526:HTUR RS19075
gene id: 543526:HTUR_RS19075
uniprot id: D2S032
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543526:HTUR RS17575
gene id: 543526:HTUR_RS17575
uniprot id: D2RR39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

543526:HTUR RS07675
gene id: 543526:HTUR_RS07675
uniprot id: D2RQX1
names: Similarity
messages: Belongs to the UPF0212 family.

543526:HTUR RS17945
gene id: 543526:HTUR_RS17945
uniprot id: D2RRA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS01745
gene id: 543526:HTUR_RS01745
uniprot id: D2RUW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

543526:HTUR RS05770
gene id: 543526:HTUR_RS05770
uniprot id: D2RZD4
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

543526:HTUR RS19275
gene id: 543526:HTUR_RS19275
uniprot id: D2S070
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

543526:HTUR RS09855
gene id: 543526:HTUR_RS09855
uniprot id: D2RT04
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS19150
gene id: 543526:HTUR_RS19150
uniprot id: D2S046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS08155
gene id: 543526:HTUR_RS08155
uniprot id: D2RRI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

543526:HTUR RS16555
gene id: 543526:HTUR_RS16555
uniprot id: D2RPS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

543526:HTUR RS08520
gene id: 543526:HTUR_RS08520
uniprot id: D2RS40
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS01040
gene id: 543526:HTUR_RS01040
uniprot id: D2RU45
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS05370
gene id: 543526:HTUR_RS05370
uniprot id: D2RZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

543526:HTUR RS20055
gene id: 543526:HTUR_RS20055
uniprot id: D2S0M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

543526:HTUR RS20350
gene id: 543526:HTUR_RS20350
uniprot id: D2S0S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS11565
gene id: 543526:HTUR_RS11565
uniprot id: D2RUQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543526:HTUR RS07835
gene id: 543526:HTUR_RS07835
uniprot id: D2RRC4
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

543526:HTUR RS01805
gene id: 543526:HTUR_RS01805
uniprot id: D2RUX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

543526:HTUR RS12475
gene id: 543526:HTUR_RS12475
uniprot id: D2RVX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

543526:HTUR RS06970
gene id: 543526:HTUR_RS06970
uniprot id: D2RQ51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

543526:HTUR RS11710
gene id: 543526:HTUR_RS11710
uniprot id: D2RV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

543526:HTUR RS01445
gene id: 543526:HTUR_RS01445
uniprot id: D2RUC7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

543526:HTUR RS15140
gene id: 543526:HTUR_RS15140
uniprot id: D2RYW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

543526:HTUR RS03155
gene id: 543526:HTUR_RS03155
uniprot id: D2RWD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

543526:HTUR RS09115
gene id: 543526:HTUR_RS09115
uniprot id: D2RSG5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

543526:HTUR RS12570
gene id: 543526:HTUR_RS12570
uniprot id: D2RVZ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

543526:HTUR RS04240
gene id: 543526:HTUR_RS04240
uniprot id: D2RXR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

543526:HTUR RS00425
gene id: 543526:HTUR_RS00425
uniprot id: D2RTE2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

543526:HTUR RS13665
gene id: 543526:HTUR_RS13665
uniprot id: D2RXB7
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

543526:HTUR RS08530
gene id: 543526:HTUR_RS08530
uniprot id: D2RS42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS03325
gene id: 543526:HTUR_RS03325
uniprot id: D2RWH2
names: Similarity
messages: Belongs to the AOR/FOR family.

543526:HTUR RS19875
gene id: 543526:HTUR_RS19875
uniprot id: D2S0I2
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS22765
gene id: 543526:HTUR_RS22765
uniprot id: D2S270
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS20515
gene id: 543526:HTUR_RS20515
uniprot id: D2S0W1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS01060
gene id: 543526:HTUR_RS01060
uniprot id: D2RU49
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

543526:HTUR RS12090
gene id: 543526:HTUR_RS12090
uniprot id: D2RVC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS24545
gene id: 543526:HTUR_RS24545
uniprot id: D2S388
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

543526:HTUR RS09370
gene id: 543526:HTUR_RS09370
uniprot id: D2RSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

543526:HTUR RS19980
gene id: 543526:HTUR_RS19980
uniprot id: D2S0K4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS06710
gene id: 543526:HTUR_RS06710
uniprot id: D2RPZ5
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

543526:HTUR RS05230
gene id: 543526:HTUR_RS05230
uniprot id: D2RYP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

543526:HTUR RS02975
gene id: 543526:HTUR_RS02975
uniprot id: D2RWA3
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

543526:HTUR RS14505
gene id: 543526:HTUR_RS14505
uniprot id: D2RY60
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

543526:HTUR RS15225
gene id: 543526:HTUR_RS15225
uniprot id: D2RYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

543526:HTUR RS15705
gene id: 543526:HTUR_RS15705
uniprot id: D2RZL4
names: Similarity
messages: Belongs to the peptidase S9C family.

543526:HTUR RS18415
gene id: 543526:HTUR_RS18415
uniprot id: D2RRY2
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

543526:HTUR RS03125
gene id: 543526:HTUR_RS03125
uniprot id: D2RWD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

543526:HTUR RS11010
gene id: 543526:HTUR_RS11010
uniprot id: D2RUE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

543526:HTUR RS06700
gene id: 543526:HTUR_RS06700
uniprot id: D2RPZ3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

543526:HTUR RS04390
gene id: 543526:HTUR_RS04390
uniprot id: D2RXU7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS20100
gene id: 543526:HTUR_RS20100
uniprot id: D2S0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

543526:HTUR RS03795
gene id: 543526:HTUR_RS03795
uniprot id: D2RX45
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

543526:HTUR RS06590
gene id: 543526:HTUR_RS06590
uniprot id: D2RPX2
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

543526:HTUR RS21440
gene id: 543526:HTUR_RS21440
uniprot id: D2S1E9
names: Similarity
messages: Belongs to the TPP enzyme family.

543526:HTUR RS08920
gene id: 543526:HTUR_RS08920
uniprot id: D2RSC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS19905
gene id: 543526:HTUR_RS19905
uniprot id: D2S0I8
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

543526:HTUR RS10430
gene id: 543526:HTUR_RS10430
uniprot id: D2RTQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS01910
gene id: 543526:HTUR_RS01910
uniprot id: D2RUZ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543526:HTUR RS01165
gene id: 543526:HTUR_RS01165
uniprot id: D2RU71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

543526:HTUR RS08965
gene id: 543526:HTUR_RS08965
uniprot id: D2RSC9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

543526:HTUR RS17110
gene id: 543526:HTUR_RS17110
uniprot id: D2RQG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS02870
gene id: 543526:HTUR_RS02870
uniprot id: D2RW81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

543526:HTUR RS11320
gene id: 543526:HTUR_RS11320
uniprot id: D2RUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

543526:HTUR RS12195
gene id: 543526:HTUR_RS12195
uniprot id: D2RVE8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

543526:HTUR RS03290
gene id: 543526:HTUR_RS03290
uniprot id: D2RWG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543526:HTUR RS18915
gene id: 543526:HTUR_RS18915
uniprot id: D2RZZ9
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

543526:HTUR RS14400
gene id: 543526:HTUR_RS14400
uniprot id: D2RY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

543526:HTUR RS02760
gene id: 543526:HTUR_RS02760
uniprot id: D2RVT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

543526:HTUR RS10285
gene id: 543526:HTUR_RS10285
uniprot id: D2RT93
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

543526:HTUR RS00005
gene id: 543526:HTUR_RS00005
uniprot id: D2RSS8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

543526:HTUR RS22280
gene id: 543526:HTUR_RS22280
uniprot id: D2S1W8
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08680
gene id: 543526:HTUR_RS08680
uniprot id: D2RS72
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

543526:HTUR RS18220
gene id: 543526:HTUR_RS18220
uniprot id: D2RRU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS13155
gene id: 543526:HTUR_RS13155
uniprot id: D2RWN8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

543526:HTUR RS13945
gene id: 543526:HTUR_RS13945
uniprot id: D2RXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

543526:HTUR RS24330
gene id: 543526:HTUR_RS24330
uniprot id: D2S343
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS20495
gene id: 543526:HTUR_RS20495
uniprot id: D2S0V7
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS08985
gene id: 543526:HTUR_RS08985
uniprot id: D2RSD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

543526:HTUR RS05955
gene id: 543526:HTUR_RS05955
uniprot id: D2RP60
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

543526:HTUR RS18215
gene id: 543526:HTUR_RS18215
uniprot id: D2RRU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS05520
gene id: 543526:HTUR_RS05520
uniprot id: D2RZ84
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

543526:HTUR RS14285
gene id: 543526:HTUR_RS14285
uniprot id: D2RY16
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12245
gene id: 543526:HTUR_RS12245
uniprot id: D2RVF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS22555
gene id: 543526:HTUR_RS22555
uniprot id: D2S237
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

543526:HTUR RS20535
gene id: 543526:HTUR_RS20535
uniprot id: D2S0W5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543526:HTUR RS10725
gene id: 543526:HTUR_RS10725
uniprot id: D2RTV8
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

543526:HTUR RS04600
gene id: 543526:HTUR_RS04600
uniprot id: D2RXY9
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS03765
gene id: 543526:HTUR_RS03765
uniprot id: D2RX40
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

543526:HTUR RS10325
gene id: 543526:HTUR_RS10325
uniprot id: D2RTA1
names: Similarity
messages: Belongs to the peptidase S8 family.

543526:HTUR RS08540
gene id: 543526:HTUR_RS08540
uniprot id: D2RS44
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS12260
gene id: 543526:HTUR_RS12260
uniprot id: D2RVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

543526:HTUR RS01830
gene id: 543526:HTUR_RS01830
uniprot id: D2RUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

543526:HTUR RS20670
gene id: 543526:HTUR_RS20670
uniprot id: D2S0Z2
names: Subcellular Location Annotation
messages: Cytoplasm

543526:HTUR RS16710
gene id: 543526:HTUR_RS16710
uniprot id: D2RQ81
names: Subcellular Location Annotation
messages: Membrane

543526:HTUR RS00045
gene id: 543526:HTUR_RS00045
uniprot id: D2RST7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543526:HTUR RS12565
gene id: 543526:HTUR_RS12565
uniprot id: D2RVZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

543526:HTUR RS03200
gene id: 543526:HTUR_RS03200
uniprot id: D2RWE6
names: Similarity
messages: Belongs to the thymidylate kinase family.

543526:HTUR RS22645
gene id: 543526:HTUR_RS22645
uniprot id: D2S250
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543526:HTUR RS20285
gene id: 543526:HTUR_RS20285
uniprot id: D2S0R5
names: Similarity
messages: Belongs to the FabD family.

543526:HTUR RS21400
gene id: 543526:HTUR_RS21400
uniprot id: D2S1E1
names: Similarity
messages: Belongs to the PEPCase type 1 family.

543526:HTUR RS13760
gene id: 543526:HTUR_RS13760
uniprot id: D2RXD6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.