539:CKV94 RS05485
gene id: 539:CKV94_RS05485
uniprot id: A0A1A9RQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

539:CKV94 RS06075
gene id: 539:CKV94_RS06075
uniprot id: A0A1A9RJC1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

539:CKV94 RS07080
gene id: 539:CKV94_RS07080
uniprot id: A0A1A9RIG1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

539:CKV94 RS06900
gene id: 539:CKV94_RS06900
uniprot id: A0A1A9RKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

539:CKV94 RS03405
gene id: 539:CKV94_RS03405
uniprot id: A0A1A9RTX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

539:CKV94 RS00760
gene id: 539:CKV94_RS00760
uniprot id: A0A8B4G0X4
names: Similarity
messages: Belongs to the nitroreductase family.

539:CKV94 RS04600
gene id: 539:CKV94_RS04600
uniprot id: A0A8B4G788
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

539:CKV94 RS00285
gene id: 539:CKV94_RS00285
uniprot id: A0A1A9RQL3
names: Similarity
messages: Belongs to the Gfa family.

539:CKV94 RS07670
gene id: 539:CKV94_RS07670
uniprot id: A0A8B4GH11
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

539:CKV94 RS10775
gene id: 539:CKV94_RS10775
uniprot id: A0A1A9RVT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

539:CKV94 RS04040
gene id: 539:CKV94_RS04040
uniprot id: A0A1A9RFJ5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

539:CKV94 RS03465
gene id: 539:CKV94_RS03465
uniprot id: A0A1A9RTW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

539:CKV94 RS10890
gene id: 539:CKV94_RS10890
uniprot id: A0A1A9RGJ2
names: Similarity
messages: Belongs to the PspA/IM30 family.

539:CKV94 RS06020
gene id: 539:CKV94_RS06020
uniprot id: A0A8B4G3T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS01240
gene id: 539:CKV94_RS01240
uniprot id: A0A8B4G5J1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS00300
gene id: 539:CKV94_RS00300
uniprot id: A0A8B4G501
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

539:CKV94 RS10740
gene id: 539:CKV94_RS10740
uniprot id: A0A1A9RI45
names: Caution
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS04735
gene id: 539:CKV94_RS04735
uniprot id: A0A1A9RBP4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

539:CKV94 RS07415
gene id: 539:CKV94_RS07415
uniprot id: A0A1A9RHQ5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

539:CKV94 RS02740
gene id: 539:CKV94_RS02740
uniprot id: A0A1A9RFA6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS00960
gene id: 539:CKV94_RS00960
uniprot id: A0A1A9RCQ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS10385
gene id: 539:CKV94_RS10385
uniprot id: A0A8B4G8L1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

539:CKV94 RS05520
gene id: 539:CKV94_RS05520
uniprot id: A0A8B4G3J7
names: Similarity
messages: Belongs to the peptidase M16 family.

539:CKV94 RS01815
gene id: 539:CKV94_RS01815
uniprot id: A0A8B4GAL4
names: Similarity
messages: Belongs to the SCO1/2 family.

539:CKV94 RS04865
gene id: 539:CKV94_RS04865
uniprot id: A0A1A9RCQ1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

539:CKV94 RS04060
gene id: 539:CKV94_RS04060
uniprot id: A0A8B4GCB6
names: Similarity
messages: Belongs to the peptidase M24B family.

539:CKV94 RS06195
gene id: 539:CKV94_RS06195
uniprot id: A0A1A9RJD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

539:CKV94 RS02105
gene id: 539:CKV94_RS02105
uniprot id: A0A1A9RSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

539:CKV94 RS05815
gene id: 539:CKV94_RS05815
uniprot id: A0A8B4G3M2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

539:CKV94 RS08475
gene id: 539:CKV94_RS08475
uniprot id: A0A8B4GHG7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS00045
gene id: 539:CKV94_RS00045
uniprot id: A0A1A9RGM7
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00320
gene id: 539:CKV94_RS00320
uniprot id: A0A1A9RRE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS08840
gene id: 539:CKV94_RS08840
uniprot id: A0A8B4GF03
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

539:CKV94 RS01185
gene id: 539:CKV94_RS01185
uniprot id: A0A8B4G191
names: Similarity
messages: Belongs to the aspartokinase family.

539:CKV94 RS07250
gene id: 539:CKV94_RS07250
uniprot id: A0A1A9RIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

539:CKV94 RS02995
gene id: 539:CKV94_RS02995
uniprot id: A0A8B4GN94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

539:CKV94 RS06255
gene id: 539:CKV94_RS06255
uniprot id: A0A8B4G854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

539:CKV94 RS06740
gene id: 539:CKV94_RS06740
uniprot id: A0A8B4GGD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

539:CKV94 RS08690
gene id: 539:CKV94_RS08690
uniprot id: A0A8B4GEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

539:CKV94 RS09260
gene id: 539:CKV94_RS09260
uniprot id: A0A8B4GRM0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

539:CKV94 RS08125
gene id: 539:CKV94_RS08125
uniprot id: A0A8B4GQY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

539:CKV94 RS03835
gene id: 539:CKV94_RS03835
uniprot id: A0A1A9RKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

539:CKV94 RS05740
gene id: 539:CKV94_RS05740
uniprot id: A0A1A9RLZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

539:CKV94 RS05455
gene id: 539:CKV94_RS05455
uniprot id: A0A1A9RRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

539:CKV94 RS08440
gene id: 539:CKV94_RS08440
uniprot id: A0A8B4GER0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

539:CKV94 RS02165
gene id: 539:CKV94_RS02165
uniprot id: A0A8B4G4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

539:CKV94 RS04860
gene id: 539:CKV94_RS04860
uniprot id: A0A8B4GEM3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

539:CKV94 RS01945
gene id: 539:CKV94_RS01945
uniprot id: A0A1A9RDL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

539:CKV94 RS05165
gene id: 539:CKV94_RS05165
uniprot id: A0A8B4GET2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

539:CKV94 RS07050
gene id: 539:CKV94_RS07050
uniprot id: A0A8B4GGJ8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

539:CKV94 RS08775
gene id: 539:CKV94_RS08775
uniprot id: A0A8B4GHL7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

539:CKV94 RS05840
gene id: 539:CKV94_RS05840
uniprot id: A0A8B4GFX4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS00795
gene id: 539:CKV94_RS00795
uniprot id: A0A8B4GC31
names: Similarity
messages: Belongs to the YfgM family.

539:CKV94 RS02045
gene id: 539:CKV94_RS02045
uniprot id: A0A8B4G1Q9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

539:CKV94 RS02875
gene id: 539:CKV94_RS02875
uniprot id: A0A8B4G6E8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS01500
gene id: 539:CKV94_RS01500
uniprot id: A0A8B4GDN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

539:CKV94 RS08960
gene id: 539:CKV94_RS08960
uniprot id: A0A8B4G9L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS02095
gene id: 539:CKV94_RS02095
uniprot id: A0A8B4G1R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

539:CKV94 RS07595
gene id: 539:CKV94_RS07595
uniprot id: A0A1A9RIE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

539:CKV94 RS08075
gene id: 539:CKV94_RS08075
uniprot id: A0A1A9RPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

539:CKV94 RS05505
gene id: 539:CKV94_RS05505
uniprot id: A0A8B4GD62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

539:CKV94 RS00225
gene id: 539:CKV94_RS00225
uniprot id: A0A8B4GBR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS10245
gene id: 539:CKV94_RS10245
uniprot id: A0A1A9R9Z8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

539:CKV94 RS03200
gene id: 539:CKV94_RS03200
uniprot id: A0A1A9RP81
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS07510
gene id: 539:CKV94_RS07510
uniprot id: A0A8B4GGV8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

539:CKV94 RS03710
gene id: 539:CKV94_RS03710
uniprot id: A0A8B4GDZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS02005
gene id: 539:CKV94_RS02005
uniprot id: A0A8B4G4I5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

539:CKV94 RS01940
gene id: 539:CKV94_RS01940
uniprot id: A0A1A9RKL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

539:CKV94 RS02710
gene id: 539:CKV94_RS02710
uniprot id: A0A1A9REF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

539:CKV94 RS04170
gene id: 539:CKV94_RS04170
uniprot id: A0A8B4GBY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

539:CKV94 RS10010
gene id: 539:CKV94_RS10010
uniprot id: A0A1A9RM40
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

539:CKV94 RS00515
gene id: 539:CKV94_RS00515
uniprot id: A0A1A9RBD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

539:CKV94 RS05275
gene id: 539:CKV94_RS05275
uniprot id: A0A8B4G5Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

539:CKV94 RS00705
gene id: 539:CKV94_RS00705
uniprot id: A0A1A9RDD4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01280
gene id: 539:CKV94_RS01280
uniprot id: A0A8B4G185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

539:CKV94 RS02410
gene id: 539:CKV94_RS02410
uniprot id: A0A1A9RNF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

539:CKV94 RS10215
gene id: 539:CKV94_RS10215
uniprot id: A0A8B4G5X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

539:CKV94 RS00935
gene id: 539:CKV94_RS00935
uniprot id: A0A8B4G5D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

539:CKV94 RS03230
gene id: 539:CKV94_RS03230
uniprot id: A0A1A9RQA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS00650
gene id: 539:CKV94_RS00650
uniprot id: A0A8B4GAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

539:CKV94 RS09645
gene id: 539:CKV94_RS09645
uniprot id: A0A8B4G9X5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

539:CKV94 RS06325
gene id: 539:CKV94_RS06325
uniprot id: A0A1A9RS27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS03805
gene id: 539:CKV94_RS03805
uniprot id: A0A1A9REU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

539:CKV94 RS08590
gene id: 539:CKV94_RS08590
uniprot id: A0A1A9RF53
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

539:CKV94 RS10985
gene id: 539:CKV94_RS10985
uniprot id: A0A8B4GFU8
names: Similarity
messages: Belongs to the GppA/Ppx family.

539:CKV94 RS05170
gene id: 539:CKV94_RS05170
uniprot id: A0A8B4G5Y1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

539:CKV94 RS06390
gene id: 539:CKV94_RS06390
uniprot id: A0A8B4GDM0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

539:CKV94 RS04035
gene id: 539:CKV94_RS04035
uniprot id: A0A8B4GE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS01390
gene id: 539:CKV94_RS01390
uniprot id: A0A8B4GCT9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

539:CKV94 RS03935
gene id: 539:CKV94_RS03935
uniprot id: A0A1A9RD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

539:CKV94 RS10290
gene id: 539:CKV94_RS10290
uniprot id: A0A1A9RHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS00005
gene id: 539:CKV94_RS00005
uniprot id: A0A1A9RSR3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS10695
gene id: 539:CKV94_RS10695
uniprot id: A0A1A9RI87
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

539:CKV94 RS09370
gene id: 539:CKV94_RS09370
uniprot id: A0A8B4GEZ7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

539:CKV94 RS08825
gene id: 539:CKV94_RS08825
uniprot id: A0A1A9RAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

539:CKV94 RS10860
gene id: 539:CKV94_RS10860
uniprot id: A0A8B4GIT4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

539:CKV94 RS02120
gene id: 539:CKV94_RS02120
uniprot id: A0A1A9RR42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS07405
gene id: 539:CKV94_RS07405
uniprot id: A0A8B4G4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

539:CKV94 RS10120
gene id: 539:CKV94_RS10120
uniprot id: A0A8B4GA52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

539:CKV94 RS07715
gene id: 539:CKV94_RS07715
uniprot id: A0A1A9RI38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

539:CKV94 RS00905
gene id: 539:CKV94_RS00905
uniprot id: A0A8B4GC47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

539:CKV94 RS05660
gene id: 539:CKV94_RS05660
uniprot id: A0A1A9RGC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

539:CKV94 RS08570
gene id: 539:CKV94_RS08570
uniprot id: A0A1A9RAV0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

539:CKV94 RS06980
gene id: 539:CKV94_RS06980
uniprot id: A0A1A9RJF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS02980
gene id: 539:CKV94_RS02980
uniprot id: A0A1A9RNS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS08240
gene id: 539:CKV94_RS08240
uniprot id: A0A8B4GEL5
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS03585
gene id: 539:CKV94_RS03585
uniprot id: A0A1A9RMD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

539:CKV94 RS02150
gene id: 539:CKV94_RS02150
uniprot id: A0A8B4G1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

539:CKV94 RS01690
gene id: 539:CKV94_RS01690
uniprot id: A0A8B4GCY8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

539:CKV94 RS02575
gene id: 539:CKV94_RS02575
uniprot id: A0A1A9RLJ6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

539:CKV94 RS10715
gene id: 539:CKV94_RS10715
uniprot id: A0A1A9RBH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

539:CKV94 RS03560
gene id: 539:CKV94_RS03560
uniprot id: A0A8B4GBM1
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

539:CKV94 RS10830
gene id: 539:CKV94_RS10830
uniprot id: A0A1A9RHQ1
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

539:CKV94 RS01175
gene id: 539:CKV94_RS01175
uniprot id: A0A8B4GA87
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

539:CKV94 RS07455
gene id: 539:CKV94_RS07455
uniprot id: A0A1A9RKG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

539:CKV94 RS00340
gene id: 539:CKV94_RS00340
uniprot id: A0A1A9RF63
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04465
gene id: 539:CKV94_RS04465
uniprot id: A0A1A9RRR2
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01465
gene id: 539:CKV94_RS01465
uniprot id: A0A1A9RER0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

539:CKV94 RS00350
gene id: 539:CKV94_RS00350
uniprot id: A0A1A9RHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

539:CKV94 RS10030
gene id: 539:CKV94_RS10030
uniprot id: A0A8B4GIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

539:CKV94 RS08250
gene id: 539:CKV94_RS08250
uniprot id: A0A8B4GEB4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

539:CKV94 RS00370
gene id: 539:CKV94_RS00370
uniprot id: A0A1A9RC83
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

539:CKV94 RS01955
gene id: 539:CKV94_RS01955
uniprot id: A0A8B4GCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

539:CKV94 RS03360
gene id: 539:CKV94_RS03360
uniprot id: A0A8B4G2F1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

539:CKV94 RS05975
gene id: 539:CKV94_RS05975
uniprot id: A0A8B4GF75
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

539:CKV94 RS01430
gene id: 539:CKV94_RS01430
uniprot id: A0A8B4G1D9
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

539:CKV94 RS10610
gene id: 539:CKV94_RS10610
uniprot id: A0A8B4GG31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

539:CKV94 RS05920
gene id: 539:CKV94_RS05920
uniprot id: A0A8B4G7Z6
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

539:CKV94 RS00785
gene id: 539:CKV94_RS00785
uniprot id: A0A1A9RGZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

539:CKV94 RS03315
gene id: 539:CKV94_RS03315
uniprot id: A0A1A9RCR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

539:CKV94 RS06880
gene id: 539:CKV94_RS06880
uniprot id: A0A1A9RJT9
names: Similarity
messages: Belongs to the DEAD box helicase family.

539:CKV94 RS01295
gene id: 539:CKV94_RS01295
uniprot id: A0A8B4GCS2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

539:CKV94 RS06850
gene id: 539:CKV94_RS06850
uniprot id: A0A8B4GFC3
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

539:CKV94 RS08135
gene id: 539:CKV94_RS08135
uniprot id: A0A8B4GEJ6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

539:CKV94 RS10050
gene id: 539:CKV94_RS10050
uniprot id: A0A8B4GFS2
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04065
gene id: 539:CKV94_RS04065
uniprot id: A0A1A9RG38
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS08265
gene id: 539:CKV94_RS08265
uniprot id: A0A8B4G980
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01310
gene id: 539:CKV94_RS01310
uniprot id: A0A8B4GCB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

539:CKV94 RS05745
gene id: 539:CKV94_RS05745
uniprot id: A0A1A9RGR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

539:CKV94 RS03475
gene id: 539:CKV94_RS03475
uniprot id: A0A8B4G6Q5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

539:CKV94 RS09430
gene id: 539:CKV94_RS09430
uniprot id: A0A8B4G5H8
names: Similarity
messages: Belongs to the FeoA family.

539:CKV94 RS05215
gene id: 539:CKV94_RS05215
uniprot id: A0A8B4G7K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

539:CKV94 RS05900
gene id: 539:CKV94_RS05900
uniprot id: A0A8B4GDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

539:CKV94 RS09480
gene id: 539:CKV94_RS09480
uniprot id: A0A8B4G5I5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

539:CKV94 RS07565
gene id: 539:CKV94_RS07565
uniprot id: A0A1A9RJ86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

539:CKV94 RS06955
gene id: 539:CKV94_RS06955
uniprot id: A0A1A9RJH2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS02640
gene id: 539:CKV94_RS02640
uniprot id: A0A8B4GBM9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

539:CKV94 RS06100
gene id: 539:CKV94_RS06100
uniprot id: A0A1A9RLW4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

539:CKV94 RS01665
gene id: 539:CKV94_RS01665
uniprot id: A0A8B4GB47
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS10900
gene id: 539:CKV94_RS10900
uniprot id: A0A1A9RHS2
names: Caution
names: Similarity
messages: Belongs to the HSP15 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03145
gene id: 539:CKV94_RS03145
uniprot id: A0A8B4G528
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS00965
gene id: 539:CKV94_RS00965
uniprot id: A0A8B4GAS0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

539:CKV94 RS00295
gene id: 539:CKV94_RS00295
uniprot id: A0A8B4G0U0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS09470
gene id: 539:CKV94_RS09470
uniprot id: A0A8B4GFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

539:CKV94 RS00450
gene id: 539:CKV94_RS00450
uniprot id: A0A8B4G532
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

539:CKV94 RS09320
gene id: 539:CKV94_RS09320
uniprot id: A0A8B4GEY7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

539:CKV94 RS04175
gene id: 539:CKV94_RS04175
uniprot id: A0A1A9RC94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

539:CKV94 RS02370
gene id: 539:CKV94_RS02370
uniprot id: A0A8B4GE57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS05995
gene id: 539:CKV94_RS05995
uniprot id: A0A8B4GPT4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS01160
gene id: 539:CKV94_RS01160
uniprot id: A0A8B4GM91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

539:CKV94 RS00120
gene id: 539:CKV94_RS00120
uniprot id: A0A8B4GCU6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

539:CKV94 RS04575
gene id: 539:CKV94_RS04575
uniprot id: A0A1A9RRE8
names: Similarity
messages: Belongs to the universal stress protein A family.

539:CKV94 RS00080
gene id: 539:CKV94_RS00080
uniprot id: A0A1A9RF14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

539:CKV94 RS03890
gene id: 539:CKV94_RS03890
uniprot id: A0A8B4GC89
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

539:CKV94 RS08210
gene id: 539:CKV94_RS08210
uniprot id: A0A1A9RFD1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS02060
gene id: 539:CKV94_RS02060
uniprot id: A0A8B4G4J5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

539:CKV94 RS02850
gene id: 539:CKV94_RS02850
uniprot id: A0A8B4GD69
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

539:CKV94 RS05280
gene id: 539:CKV94_RS05280
uniprot id: A0A8B4GFM6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

539:CKV94 RS10815
gene id: 539:CKV94_RS10815
uniprot id: A0A8B4GSH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

539:CKV94 RS09210
gene id: 539:CKV94_RS09210
uniprot id: A0A1A9RPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

539:CKV94 RS05235
gene id: 539:CKV94_RS05235
uniprot id: A0A1A9RRV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

539:CKV94 RS10975
gene id: 539:CKV94_RS10975
uniprot id: A0A1A9RH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

539:CKV94 RS07675
gene id: 539:CKV94_RS07675
uniprot id: A0A8B4GQQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

539:CKV94 RS06135
gene id: 539:CKV94_RS06135
uniprot id: A0A8B4GPU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

539:CKV94 RS03060
gene id: 539:CKV94_RS03060
uniprot id: A0A1A9RDI6
names: Caution
names: Similarity
messages: Belongs to the ArsC family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS01750
gene id: 539:CKV94_RS01750
uniprot id: A0A8B4GDT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

539:CKV94 RS08525
gene id: 539:CKV94_RS08525
uniprot id: A0A8B4GHH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS05015
gene id: 539:CKV94_RS05015
uniprot id: A0A1A9RDH4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

539:CKV94 RS01700
gene id: 539:CKV94_RS01700
uniprot id: A0A8B4GDS8
names: Similarity
messages: Belongs to the peptidase C40 family.

539:CKV94 RS04845
gene id: 539:CKV94_RS04845
uniprot id: A0A8B4G345
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

539:CKV94 RS06940
gene id: 539:CKV94_RS06940
uniprot id: A0A1A9RJF5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

539:CKV94 RS10000
gene id: 539:CKV94_RS10000
uniprot id: A0A1A9RKX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

539:CKV94 RS00435
gene id: 539:CKV94_RS00435
uniprot id: A0A1A9RC76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

539:CKV94 RS06395
gene id: 539:CKV94_RS06395
uniprot id: A0A8B4GD65
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS08850
gene id: 539:CKV94_RS08850
uniprot id: A0A1A9R918
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

539:CKV94 RS07375
gene id: 539:CKV94_RS07375
uniprot id: A0A8B4GGR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS00825
gene id: 539:CKV94_RS00825
uniprot id: A0A1A9RC22
names: Similarity
messages: Belongs to the P(II) protein family.

539:CKV94 RS02715
gene id: 539:CKV94_RS02715
uniprot id: A0A8B4GBP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

539:CKV94 RS04220
gene id: 539:CKV94_RS04220
uniprot id: A0A1A9RT75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

539:CKV94 RS06460
gene id: 539:CKV94_RS06460
uniprot id: A0A1A9RHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

539:CKV94 RS03450
gene id: 539:CKV94_RS03450
uniprot id: A0A8B4GDI5
names: Similarity
messages: Belongs to the PhoH family.

539:CKV94 RS01395
gene id: 539:CKV94_RS01395
uniprot id: A0A8B4G469
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS09515
gene id: 539:CKV94_RS09515
uniprot id: A0A8B4GGZ5
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01680
gene id: 539:CKV94_RS01680
uniprot id: A0A8B4G1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

539:CKV94 RS02475
gene id: 539:CKV94_RS02475
uniprot id: A0A1A9RD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

539:CKV94 RS10910
gene id: 539:CKV94_RS10910
uniprot id: A0A1A9RGX8
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01975
gene id: 539:CKV94_RS01975
uniprot id: A0A8B4G1P4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

539:CKV94 RS07470
gene id: 539:CKV94_RS07470
uniprot id: A0A8B4GFQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

539:CKV94 RS04195
gene id: 539:CKV94_RS04195
uniprot id: A0A8B4G720
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

539:CKV94 RS00475
gene id: 539:CKV94_RS00475
uniprot id: A0A1A9RH64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

539:CKV94 RS09195
gene id: 539:CKV94_RS09195
uniprot id: A0A1A9RPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

539:CKV94 RS06205
gene id: 539:CKV94_RS06205
uniprot id: A0A1A9RKN8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

539:CKV94 RS01635
gene id: 539:CKV94_RS01635
uniprot id: A0A1A9RCX3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS00690
gene id: 539:CKV94_RS00690
uniprot id: A0A8B4GLY7
names: Similarity
messages: Belongs to the ArsC family.

539:CKV94 RS08270
gene id: 539:CKV94_RS08270
uniprot id: A0A8B4GGC8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

539:CKV94 RS07950
gene id: 539:CKV94_RS07950
uniprot id: A0A1A9RQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

539:CKV94 RS07475
gene id: 539:CKV94_RS07475
uniprot id: A0A1A9RIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

539:CKV94 RS00980
gene id: 539:CKV94_RS00980
uniprot id: A0A8B4G158
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

539:CKV94 RS00360
gene id: 539:CKV94_RS00360
uniprot id: A0A8B4G3P6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS08060
gene id: 539:CKV94_RS08060
uniprot id: A0A8B4GEI0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

539:CKV94 RS10345
gene id: 539:CKV94_RS10345
uniprot id: A0A8B4GHI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

539:CKV94 RS04410
gene id: 539:CKV94_RS04410
uniprot id: A0A8B4GNZ2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

539:CKV94 RS03000
gene id: 539:CKV94_RS03000
uniprot id: A0A1A9RFC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

539:CKV94 RS05490
gene id: 539:CKV94_RS05490
uniprot id: A0A1A9RP55
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

539:CKV94 RS00270
gene id: 539:CKV94_RS00270
uniprot id: A0A1A9RI24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS06490
gene id: 539:CKV94_RS06490
uniprot id: A0A8B4GF44
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS02340
gene id: 539:CKV94_RS02340
uniprot id: A0A8B4GAX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

539:CKV94 RS08325
gene id: 539:CKV94_RS08325
uniprot id: A0A1A9RFA9
names: Subcellular Location Annotation
messages: Periplasm

539:CKV94 RS00670
gene id: 539:CKV94_RS00670
uniprot id: A0A1A9RRY3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

539:CKV94 RS02490
gene id: 539:CKV94_RS02490
uniprot id: A0A8B4GB16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS06745
gene id: 539:CKV94_RS06745
uniprot id: A0A8B4GQ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS01585
gene id: 539:CKV94_RS01585
uniprot id: A0A1A9RCT4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS02415
gene id: 539:CKV94_RS02415
uniprot id: A0A8B4G4R3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS03080
gene id: 539:CKV94_RS03080
uniprot id: A0A1A9RFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

539:CKV94 RS08090
gene id: 539:CKV94_RS08090
uniprot id: A0A8B4G7H5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

539:CKV94 RS05845
gene id: 539:CKV94_RS05845
uniprot id: A0A8B4GPQ5
names: Similarity
messages: Belongs to the RutC family.

539:CKV94 RS08235
gene id: 539:CKV94_RS08235
uniprot id: A0A1A9REB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

539:CKV94 RS02395
gene id: 539:CKV94_RS02395
uniprot id: A0A1A9RNE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

539:CKV94 RS10390
gene id: 539:CKV94_RS10390
uniprot id: A0A1A9RH22
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

539:CKV94 RS03005
gene id: 539:CKV94_RS03005
uniprot id: A0A8B4GBU7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

539:CKV94 RS06375
gene id: 539:CKV94_RS06375
uniprot id: A0A8B4GG73
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

539:CKV94 RS10805
gene id: 539:CKV94_RS10805
uniprot id: A0A8B4G8U2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

539:CKV94 RS10110
gene id: 539:CKV94_RS10110
uniprot id: A0A1A9RMW3
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00710
gene id: 539:CKV94_RS00710
uniprot id: A0A8B4G0W5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

539:CKV94 RS10145
gene id: 539:CKV94_RS10145
uniprot id: A0A1A9RPE2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

539:CKV94 RS10420
gene id: 539:CKV94_RS10420
uniprot id: A0A8B4G610
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

539:CKV94 RS07380
gene id: 539:CKV94_RS07380
uniprot id: A0A8B4GQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

539:CKV94 RS06155
gene id: 539:CKV94_RS06155
uniprot id: A0A1A9RLV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

539:CKV94 RS09535
gene id: 539:CKV94_RS09535
uniprot id: A0A8B4G5L3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

539:CKV94 RS02055
gene id: 539:CKV94_RS02055
uniprot id: A0A8B4GD51
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

539:CKV94 RS03990
gene id: 539:CKV94_RS03990
uniprot id: A0A8B4GCA6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

539:CKV94 RS07060
gene id: 539:CKV94_RS07060
uniprot id: A0A8B4GFG1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

539:CKV94 RS03760
gene id: 539:CKV94_RS03760
uniprot id: A0A8B4GE01
names: Similarity
messages: Belongs to the peptidase U62 family.

539:CKV94 RS06815
gene id: 539:CKV94_RS06815
uniprot id: A0A1A9RIW6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

539:CKV94 RS07105
gene id: 539:CKV94_RS07105
uniprot id: A0A8B4GQD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS03810
gene id: 539:CKV94_RS03810
uniprot id: A0A1A9RRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

539:CKV94 RS08785
gene id: 539:CKV94_RS08785
uniprot id: A0A8B4GGI7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

539:CKV94 RS06600
gene id: 539:CKV94_RS06600
uniprot id: A0A1A9RIM0
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS06345
gene id: 539:CKV94_RS06345
uniprot id: A0A8B4GD55
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

539:CKV94 RS05180
gene id: 539:CKV94_RS05180
uniprot id: A0A8B4GPD4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

539:CKV94 RS07770
gene id: 539:CKV94_RS07770
uniprot id: A0A8B4GG53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

539:CKV94 RS10325
gene id: 539:CKV94_RS10325
uniprot id: A0A1A9RI21
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

539:CKV94 RS05810
gene id: 539:CKV94_RS05810
uniprot id: A0A8B4GCV8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

539:CKV94 RS05010
gene id: 539:CKV94_RS05010
uniprot id: A0A8B4G7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

539:CKV94 RS06760
gene id: 539:CKV94_RS06760
uniprot id: A0A1A9RGZ4
names: Similarity
messages: Belongs to the Fur family.

539:CKV94 RS07550
gene id: 539:CKV94_RS07550
uniprot id: A0A1A9RKY3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

539:CKV94 RS09450
gene id: 539:CKV94_RS09450
uniprot id: A0A8B4G848
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

539:CKV94 RS07755
gene id: 539:CKV94_RS07755
uniprot id: A0A8B4G4L4
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

539:CKV94 RS02190
gene id: 539:CKV94_RS02190
uniprot id: A0A1A9RP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

539:CKV94 RS04875
gene id: 539:CKV94_RS04875
uniprot id: A0A8B4GP79
names: Similarity
messages: Belongs to the GARS family.

539:CKV94 RS02145
gene id: 539:CKV94_RS02145
uniprot id: A0A8B4G1Q7
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS03175
gene id: 539:CKV94_RS03175
uniprot id: A0A8B4G6M3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

539:CKV94 RS00155
gene id: 539:CKV94_RS00155
uniprot id: A0A8B4GC55
names: Similarity
messages: Belongs to the UPF0758 family.

539:CKV94 RS00640
gene id: 539:CKV94_RS00640
uniprot id: A0A8B4GLX4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

539:CKV94 RS02810
gene id: 539:CKV94_RS02810
uniprot id: A0A1A9RMD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

539:CKV94 RS00625
gene id: 539:CKV94_RS00625
uniprot id: A0A1A9RCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

539:CKV94 RS00605
gene id: 539:CKV94_RS00605
uniprot id: A0A1A9RH99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

539:CKV94 RS06920
gene id: 539:CKV94_RS06920
uniprot id: A0A8B4GDJ8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

539:CKV94 RS07035
gene id: 539:CKV94_RS07035
uniprot id: A0A1A9RJY3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS08230
gene id: 539:CKV94_RS08230
uniprot id: A0A1A9RTF2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

539:CKV94 RS04350
gene id: 539:CKV94_RS04350
uniprot id: A0A8B4G2Y4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04565
gene id: 539:CKV94_RS04565
uniprot id: A0A8B4GF93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

539:CKV94 RS05120
gene id: 539:CKV94_RS05120
uniprot id: A0A8B4GFJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

539:CKV94 RS07625
gene id: 539:CKV94_RS07625
uniprot id: A0A8B4GFU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

539:CKV94 RS08675
gene id: 539:CKV94_RS08675
uniprot id: A0A8B4GHK0
names: Similarity
messages: Belongs to the asparaginase 1 family.

539:CKV94 RS08810
gene id: 539:CKV94_RS08810
uniprot id: A0A8B4G9I9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

539:CKV94 RS02185
gene id: 539:CKV94_RS02185
uniprot id: A0A1A9RN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

539:CKV94 RS08190
gene id: 539:CKV94_RS08190
uniprot id: A0A8B4GEK5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

539:CKV94 RS01460
gene id: 539:CKV94_RS01460
uniprot id: A0A1A9RDY4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05790
gene id: 539:CKV94_RS05790
uniprot id: A0A8B4G687
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

539:CKV94 RS02035
gene id: 539:CKV94_RS02035
uniprot id: A0A8B4GAQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS01380
gene id: 539:CKV94_RS01380
uniprot id: A0A1A9REI5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

539:CKV94 RS03430
gene id: 539:CKV94_RS03430
uniprot id: A0A8B4GDT6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

539:CKV94 RS08845
gene id: 539:CKV94_RS08845
uniprot id: A0A8B4GEP5
names: Similarity
messages: Belongs to the fabD family.

539:CKV94 RS02385
gene id: 539:CKV94_RS02385
uniprot id: A0A8B4GBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

539:CKV94 RS05400
gene id: 539:CKV94_RS05400
uniprot id: A0A8B4G3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

539:CKV94 RS06545
gene id: 539:CKV94_RS06545
uniprot id: A0A8B4GF57
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

539:CKV94 RS03480
gene id: 539:CKV94_RS03480
uniprot id: A0A1A9RSE7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS10300
gene id: 539:CKV94_RS10300
uniprot id: A0A1A9RLU0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

539:CKV94 RS03330
gene id: 539:CKV94_RS03330
uniprot id: A0A8B4G551
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

539:CKV94 RS01020
gene id: 539:CKV94_RS01020
uniprot id: A0A8B4GAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

539:CKV94 RS10095
gene id: 539:CKV94_RS10095
uniprot id: A0A8B4GHC1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS01080
gene id: 539:CKV94_RS01080
uniprot id: A0A8B4G135
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

539:CKV94 RS10700
gene id: 539:CKV94_RS10700
uniprot id: A0A1A9RBV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

539:CKV94 RS09905
gene id: 539:CKV94_RS09905
uniprot id: A0A1A9RJC2
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00040
gene id: 539:CKV94_RS00040
uniprot id: A0A8B4G0H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

539:CKV94 RS04240
gene id: 539:CKV94_RS04240
uniprot id: A0A8B4GBZ8
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

539:CKV94 RS10970
gene id: 539:CKV94_RS10970
uniprot id: A0A8B4GSK1
names: Similarity
messages: Belongs to the GSP E family.

539:CKV94 RS04020
gene id: 539:CKV94_RS04020
uniprot id: A0A8B4GBW3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

539:CKV94 RS05285
gene id: 539:CKV94_RS05285
uniprot id: A0A8B4GPF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS05410
gene id: 539:CKV94_RS05410
uniprot id: A0A1A9RTA9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

539:CKV94 RS10275
gene id: 539:CKV94_RS10275
uniprot id: A0A8B4GHB9
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS02700
gene id: 539:CKV94_RS02700
uniprot id: A0A1A9RF13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

539:CKV94 RS03520
gene id: 539:CKV94_RS03520
uniprot id: A0A8B4G2J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

539:CKV94 RS09595
gene id: 539:CKV94_RS09595
uniprot id: A0A8B4G9W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS03045
gene id: 539:CKV94_RS03045
uniprot id: A0A8B4GEH6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

539:CKV94 RS10370
gene id: 539:CKV94_RS10370
uniprot id: A0A1A9RFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

539:CKV94 RS03680
gene id: 539:CKV94_RS03680
uniprot id: A0A8B4GC54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

539:CKV94 RS08965
gene id: 539:CKV94_RS08965
uniprot id: A0A8B4GGQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

539:CKV94 RS07355
gene id: 539:CKV94_RS07355
uniprot id: A0A8B4G4G1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

539:CKV94 RS10240
gene id: 539:CKV94_RS10240
uniprot id: A0A8B4GS62
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

539:CKV94 RS10765
gene id: 539:CKV94_RS10765
uniprot id: A0A1A9RHR1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

539:CKV94 RS05450
gene id: 539:CKV94_RS05450
uniprot id: A0A1A9RSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

539:CKV94 RS09245
gene id: 539:CKV94_RS09245
uniprot id: A0A1A9RPW4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

539:CKV94 RS08290
gene id: 539:CKV94_RS08290
uniprot id: A0A8B4GG85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

539:CKV94 RS02595
gene id: 539:CKV94_RS02595
uniprot id: A0A8B4G215
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

539:CKV94 RS07025
gene id: 539:CKV94_RS07025
uniprot id: A0A1A9RK03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

539:CKV94 RS02835
gene id: 539:CKV94_RS02835
uniprot id: A0A1A9RGN4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

539:CKV94 RS10190
gene id: 539:CKV94_RS10190
uniprot id: A0A8B4GIE6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS04130
gene id: 539:CKV94_RS04130
uniprot id: A0A8B4G710
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

539:CKV94 RS04075
gene id: 539:CKV94_RS04075
uniprot id: A0A1A9RU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

539:CKV94 RS05750
gene id: 539:CKV94_RS05750
uniprot id: A0A8B4GER7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

539:CKV94 RS05880
gene id: 539:CKV94_RS05880
uniprot id: A0A8B4GF52
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

539:CKV94 RS06685
gene id: 539:CKV94_RS06685
uniprot id: A0A8B4G6Q7
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

539:CKV94 RS08685
gene id: 539:CKV94_RS08685
uniprot id: A0A1A9R9Z4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

539:CKV94 RS00010
gene id: 539:CKV94_RS00010
uniprot id: A0A8B4G3I6
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04070
gene id: 539:CKV94_RS04070
uniprot id: A0A1A9RS30
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS02025
gene id: 539:CKV94_RS02025
uniprot id: A0A8B4GCR0
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS07655
gene id: 539:CKV94_RS07655
uniprot id: A0A1A9RJQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS07705
gene id: 539:CKV94_RS07705
uniprot id: A0A8B4G4N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

539:CKV94 RS10235
gene id: 539:CKV94_RS10235
uniprot id: A0A8B4GIF5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

539:CKV94 RS01860
gene id: 539:CKV94_RS01860
uniprot id: A0A8B4GB82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

539:CKV94 RS00850
gene id: 539:CKV94_RS00850
uniprot id: A0A1A9RH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

539:CKV94 RS06830
gene id: 539:CKV94_RS06830
uniprot id: A0A1A9RKV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS09425
gene id: 539:CKV94_RS09425
uniprot id: A0A8B4GF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

539:CKV94 RS02030
gene id: 539:CKV94_RS02030
uniprot id: A0A8B4GBB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS06265
gene id: 539:CKV94_RS06265
uniprot id: A0A8B4G6H0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

539:CKV94 RS05405
gene id: 539:CKV94_RS05405
uniprot id: A0A1A9RTI2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

539:CKV94 RS07845
gene id: 539:CKV94_RS07845
uniprot id: A0A8B4GH40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS01275
gene id: 539:CKV94_RS01275
uniprot id: A0A8B4GAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

539:CKV94 RS06200
gene id: 539:CKV94_RS06200
uniprot id: A0A1A9RL41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

539:CKV94 RS10500
gene id: 539:CKV94_RS10500
uniprot id: A0A1A9RI04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

539:CKV94 RS00310
gene id: 539:CKV94_RS00310
uniprot id: A0A1A9RG95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS05240
gene id: 539:CKV94_RS05240
uniprot id: A0A1A9RT72
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

539:CKV94 RS04180
gene id: 539:CKV94_RS04180
uniprot id: A0A1A9RDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

539:CKV94 RS04580
gene id: 539:CKV94_RS04580
uniprot id: A0A8B4GCM8
names: Similarity
messages: Belongs to the GSP E family.

539:CKV94 RS00455
gene id: 539:CKV94_RS00455
uniprot id: A0A1A9RH79
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

539:CKV94 RS04515
gene id: 539:CKV94_RS04515
uniprot id: A0A1A9RR11
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

539:CKV94 RS02500
gene id: 539:CKV94_RS02500
uniprot id: A0A1A9RP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

539:CKV94 RS02495
gene id: 539:CKV94_RS02495
uniprot id: A0A8B4G1Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

539:CKV94 RS06180
gene id: 539:CKV94_RS06180
uniprot id: A0A1A9RL36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

539:CKV94 RS09630
gene id: 539:CKV94_RS09630
uniprot id: A0A8B4GF50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

539:CKV94 RS09675
gene id: 539:CKV94_RS09675
uniprot id: A0A8B4GF62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

539:CKV94 RS09410
gene id: 539:CKV94_RS09410
uniprot id: A0A8B4GRP8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

539:CKV94 RS10545
gene id: 539:CKV94_RS10545
uniprot id: A0A1A9RIS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

539:CKV94 RS10980
gene id: 539:CKV94_RS10980
uniprot id: A0A1A9RGX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS02430
gene id: 539:CKV94_RS02430
uniprot id: A0A8B4GCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

539:CKV94 RS03440
gene id: 539:CKV94_RS03440
uniprot id: A0A8B4GEN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

539:CKV94 RS09710
gene id: 539:CKV94_RS09710
uniprot id: A0A1A9RCD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

539:CKV94 RS09940
gene id: 539:CKV94_RS09940
uniprot id: A0A8B4GFN9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

539:CKV94 RS02195
gene id: 539:CKV94_RS02195
uniprot id: A0A8B4G1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

539:CKV94 RS10440
gene id: 539:CKV94_RS10440
uniprot id: A0A1A9RHU6
names: Caution
names: Similarity
messages: Belongs to the GbsR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS04080
gene id: 539:CKV94_RS04080
uniprot id: A0A8B4G700
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

539:CKV94 RS10185
gene id: 539:CKV94_RS10185
uniprot id: A0A1A9RNM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

539:CKV94 RS00800
gene id: 539:CKV94_RS00800
uniprot id: A0A1A9RGY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS09250
gene id: 539:CKV94_RS09250
uniprot id: A0A8B4G815
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

539:CKV94 RS07975
gene id: 539:CKV94_RS07975
uniprot id: A0A1A9RHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

539:CKV94 RS03795
gene id: 539:CKV94_RS03795
uniprot id: A0A1A9RE86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

539:CKV94 RS05540
gene id: 539:CKV94_RS05540
uniprot id: A0A1A9RPY4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

539:CKV94 RS03225
gene id: 539:CKV94_RS03225
uniprot id: A0A1A9RQ93
names: Similarity
messages: Belongs to the DEAD box helicase family.

539:CKV94 RS01450
gene id: 539:CKV94_RS01450
uniprot id: A0A1A9RFS3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03885
gene id: 539:CKV94_RS03885
uniprot id: A0A8B4GDS3
names: Similarity
messages: Belongs to the RutC family.

539:CKV94 RS06800
gene id: 539:CKV94_RS06800
uniprot id: A0A1A9RJW5
names: Similarity
messages: Belongs to the UPF0145 family.

539:CKV94 RS03705
gene id: 539:CKV94_RS03705
uniprot id: A0A8B4G6M3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

539:CKV94 RS07785
gene id: 539:CKV94_RS07785
uniprot id: A0A8B4G7C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

539:CKV94 RS07955
gene id: 539:CKV94_RS07955
uniprot id: A0A8B4GQV9
names: Similarity
messages: Belongs to the UPF0053 family.

539:CKV94 RS07600
gene id: 539:CKV94_RS07600
uniprot id: A0A8B4GG21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

539:CKV94 RS00015
gene id: 539:CKV94_RS00015
uniprot id: A0A8B4GCR9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

539:CKV94 RS00110
gene id: 539:CKV94_RS00110
uniprot id: A0A1A9RHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

539:CKV94 RS10015
gene id: 539:CKV94_RS10015
uniprot id: A0A8B4GA35
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

539:CKV94 RS08420
gene id: 539:CKV94_RS08420
uniprot id: A0A8B4G7M8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

539:CKV94 RS10560
gene id: 539:CKV94_RS10560
uniprot id: A0A8B4GFM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

539:CKV94 RS00205
gene id: 539:CKV94_RS00205
uniprot id: A0A8B4GC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

539:CKV94 RS04045
gene id: 539:CKV94_RS04045
uniprot id: A0A8B4GEZ4
names: Similarity
messages: Belongs to the peptidase M24B family.

539:CKV94 RS10665
gene id: 539:CKV94_RS10665
uniprot id: A0A1A9RHN2
names: Similarity
messages: Belongs to the peptidase S11 family.

539:CKV94 RS08285
gene id: 539:CKV94_RS08285
uniprot id: A0A8B4GR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

539:CKV94 RS06725
gene id: 539:CKV94_RS06725
uniprot id: A0A8B4G8G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

539:CKV94 RS06405
gene id: 539:CKV94_RS06405
uniprot id: A0A8B4G3Y0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

539:CKV94 RS05270
gene id: 539:CKV94_RS05270
uniprot id: A0A1A9RSG9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

539:CKV94 RS06115
gene id: 539:CKV94_RS06115
uniprot id: A0A1A9RLE4
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS07900
gene id: 539:CKV94_RS07900
uniprot id: A0A8B4GQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

539:CKV94 RS01075
gene id: 539:CKV94_RS01075
uniprot id: A0A1A9RHI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

539:CKV94 RS07460
gene id: 539:CKV94_RS07460
uniprot id: A0A8B4GGU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

539:CKV94 RS07830
gene id: 539:CKV94_RS07830
uniprot id: A0A1A9RI10
names: Similarity
messages: Belongs to the BolA/IbaG family.

539:CKV94 RS03265
gene id: 539:CKV94_RS03265
uniprot id: A0A8B4GNE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

539:CKV94 RS08760
gene id: 539:CKV94_RS08760
uniprot id: A0A8B4G9H6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

539:CKV94 RS01425
gene id: 539:CKV94_RS01425
uniprot id: A0A8B4G1C2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

539:CKV94 RS06520
gene id: 539:CKV94_RS06520
uniprot id: A0A8B4GFG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS01610
gene id: 539:CKV94_RS01610
uniprot id: A0A1A9RB61
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

539:CKV94 RS10915
gene id: 539:CKV94_RS10915
uniprot id: A0A1A9RH30
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

539:CKV94 RS06715
gene id: 539:CKV94_RS06715
uniprot id: A0A8B4G426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

539:CKV94 RS02990
gene id: 539:CKV94_RS02990
uniprot id: A0A8B4GEG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

539:CKV94 RS02525
gene id: 539:CKV94_RS02525
uniprot id: A0A8B4GN09
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00590
gene id: 539:CKV94_RS00590
uniprot id: A0A8B4GLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

539:CKV94 RS03275
gene id: 539:CKV94_RS03275
uniprot id: A0A1A9RSY6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

539:CKV94 RS04820
gene id: 539:CKV94_RS04820
uniprot id: A0A1A9RDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

539:CKV94 RS07960
gene id: 539:CKV94_RS07960
uniprot id: A0A8B4GG20
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

539:CKV94 RS07230
gene id: 539:CKV94_RS07230
uniprot id: A0A8B4GDQ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

539:CKV94 RS02140
gene id: 539:CKV94_RS02140
uniprot id: A0A8B4GAS8
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS08670
gene id: 539:CKV94_RS08670
uniprot id: A0A8B4G7R8
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS10645
gene id: 539:CKV94_RS10645
uniprot id: A0A8B4G8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

539:CKV94 RS10485
gene id: 539:CKV94_RS10485
uniprot id: A0A8B4G8N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

539:CKV94 RS10925
gene id: 539:CKV94_RS10925
uniprot id: A0A8B4GG92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

539:CKV94 RS08410
gene id: 539:CKV94_RS08410
uniprot id: A0A1A9RL25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

539:CKV94 RS09755
gene id: 539:CKV94_RS09755
uniprot id: A0A8B4GH34
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04505
gene id: 539:CKV94_RS04505
uniprot id: A0A1A9RSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS05245
gene id: 539:CKV94_RS05245
uniprot id: A0A1A9RS36
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

539:CKV94 RS09255
gene id: 539:CKV94_RS09255
uniprot id: A0A8B4GHV5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

539:CKV94 RS02775
gene id: 539:CKV94_RS02775
uniprot id: A0A8B4G6C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

539:CKV94 RS08865
gene id: 539:CKV94_RS08865
uniprot id: A0A8B4GGP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS09420
gene id: 539:CKV94_RS09420
uniprot id: A0A8B4GFC6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

539:CKV94 RS07430
gene id: 539:CKV94_RS07430
uniprot id: A0A8B4GFP2
names: Similarity
messages: Belongs to the HesB/IscA family.

539:CKV94 RS03050
gene id: 539:CKV94_RS03050
uniprot id: A0A1A9RGQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS05160
gene id: 539:CKV94_RS05160
uniprot id: A0A1A9RHA7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

539:CKV94 RS06840
gene id: 539:CKV94_RS06840
uniprot id: A0A1A9RJF4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS07030
gene id: 539:CKV94_RS07030
uniprot id: A0A1A9RJ26
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05370
gene id: 539:CKV94_RS05370
uniprot id: A0A8B4G616
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

539:CKV94 RS02890
gene id: 539:CKV94_RS02890
uniprot id: A0A8B4GN75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

539:CKV94 RS08735
gene id: 539:CKV94_RS08735
uniprot id: A0A8B4GGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

539:CKV94 RS06160
gene id: 539:CKV94_RS06160
uniprot id: A0A1A9RK92
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

539:CKV94 RS01915
gene id: 539:CKV94_RS01915
uniprot id: A0A8B4GB96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

539:CKV94 RS08900
gene id: 539:CKV94_RS08900
uniprot id: A0A1A9RC42
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

539:CKV94 RS09505
gene id: 539:CKV94_RS09505
uniprot id: A0A8B4GHZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

539:CKV94 RS10810
gene id: 539:CKV94_RS10810
uniprot id: A0A8B4GIS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

539:CKV94 RS01475
gene id: 539:CKV94_RS01475
uniprot id: A0A8B4G1D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

539:CKV94 RS03660
gene id: 539:CKV94_RS03660
uniprot id: A0A8B4G599
names: Similarity
messages: Belongs to the RecJ family.

539:CKV94 RS07700
gene id: 539:CKV94_RS07700
uniprot id: A0A1A9RT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS07385
gene id: 539:CKV94_RS07385
uniprot id: A0A8B4GFN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

539:CKV94 RS00240
gene id: 539:CKV94_RS00240
uniprot id: A0A8B4G0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

539:CKV94 RS02915
gene id: 539:CKV94_RS02915
uniprot id: A0A1A9RPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

539:CKV94 RS07905
gene id: 539:CKV94_RS07905
uniprot id: A0A8B4GG07
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

539:CKV94 RS00680
gene id: 539:CKV94_RS00680
uniprot id: A0A8B4G3U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

539:CKV94 RS03155
gene id: 539:CKV94_RS03155
uniprot id: A0A1A9RFC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

539:CKV94 RS01775
gene id: 539:CKV94_RS01775
uniprot id: A0A8B4G1I9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

539:CKV94 RS10835
gene id: 539:CKV94_RS10835
uniprot id: A0A8B4G699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

539:CKV94 RS01880
gene id: 539:CKV94_RS01880
uniprot id: A0A8B4G5W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

539:CKV94 RS03820
gene id: 539:CKV94_RS03820
uniprot id: A0A1A9RMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

539:CKV94 RS06150
gene id: 539:CKV94_RS06150
uniprot id: A0A1A9RIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

539:CKV94 RS04960
gene id: 539:CKV94_RS04960
uniprot id: A0A8B4G7G3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

539:CKV94 RS09000
gene id: 539:CKV94_RS09000
uniprot id: A0A8B4G596
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00290
gene id: 539:CKV94_RS00290
uniprot id: A0A1A9RF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

539:CKV94 RS00885
gene id: 539:CKV94_RS00885
uniprot id: A0A8B4G3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS06050
gene id: 539:CKV94_RS06050
uniprot id: A0A1A9RLX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

539:CKV94 RS08050
gene id: 539:CKV94_RS08050
uniprot id: A0A1A9RQY9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

539:CKV94 RS07395
gene id: 539:CKV94_RS07395
uniprot id: A0A8B4GDT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS04030
gene id: 539:CKV94_RS04030
uniprot id: A0A1A9RRN3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

539:CKV94 RS04775
gene id: 539:CKV94_RS04775
uniprot id: A0A1A9RDL2
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

539:CKV94 RS07945
gene id: 539:CKV94_RS07945
uniprot id: A0A8B4G7F1
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

539:CKV94 RS11055
gene id: 539:CKV94_RS11055
uniprot id: A0A1A9RRF8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS01715
gene id: 539:CKV94_RS01715
uniprot id: A0A8B4GB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

539:CKV94 RS09685
gene id: 539:CKV94_RS09685
uniprot id: A0A8B4G5M9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

539:CKV94 RS02285
gene id: 539:CKV94_RS02285
uniprot id: A0A8B4GBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

539:CKV94 RS00790
gene id: 539:CKV94_RS00790
uniprot id: A0A8B4GM06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

539:CKV94 RS06145
gene id: 539:CKV94_RS06145
uniprot id: A0A1A9RKQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

539:CKV94 RS10365
gene id: 539:CKV94_RS10365
uniprot id: A0A8B4G607
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

539:CKV94 RS02735
gene id: 539:CKV94_RS02735
uniprot id: A0A1A9RDE0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
messages: Homodimer.

539:CKV94 RS02765
gene id: 539:CKV94_RS02765
uniprot id: A0A8B4G246
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

539:CKV94 RS10270
gene id: 539:CKV94_RS10270
uniprot id: A0A8B4GA82
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

539:CKV94 RS07645
gene id: 539:CKV94_RS07645
uniprot id: A0A8B4G4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

539:CKV94 RS00365
gene id: 539:CKV94_RS00365
uniprot id: A0A8B4GCZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

539:CKV94 RS06060
gene id: 539:CKV94_RS06060
uniprot id: A0A1A9RNJ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS06275
gene id: 539:CKV94_RS06275
uniprot id: A0A8B4GPW5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

539:CKV94 RS02985
gene id: 539:CKV94_RS02985
uniprot id: A0A1A9RFA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

539:CKV94 RS02065
gene id: 539:CKV94_RS02065
uniprot id: A0A1A9RV75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS00090
gene id: 539:CKV94_RS00090
uniprot id: A0A1A9RTB5
names: Caution
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS07680
gene id: 539:CKV94_RS07680
uniprot id: A0A8B4GFW2
names: Similarity
messages: Belongs to the YciI family.

539:CKV94 RS01985
gene id: 539:CKV94_RS01985
uniprot id: A0A8B4GD41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS07365
gene id: 539:CKV94_RS07365
uniprot id: A0A8B4GFW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

539:CKV94 RS06765
gene id: 539:CKV94_RS06765
uniprot id: A0A8B4G431
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

539:CKV94 RS04925
gene id: 539:CKV94_RS04925
uniprot id: A0A8B4GFF6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

539:CKV94 RS00050
gene id: 539:CKV94_RS00050
uniprot id: A0A8B4G4U9
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS10590
gene id: 539:CKV94_RS10590
uniprot id: A0A1A9RJ00
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family.

539:CKV94 RS01630
gene id: 539:CKV94_RS01630
uniprot id: A0A1A9RT86
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS06175
gene id: 539:CKV94_RS06175
uniprot id: A0A1A9RJU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

539:CKV94 RS05670
gene id: 539:CKV94_RS05670
uniprot id: A0A1A9RQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

539:CKV94 RS01675
gene id: 539:CKV94_RS01675
uniprot id: A0A8B4G1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

539:CKV94 RS03940
gene id: 539:CKV94_RS03940
uniprot id: A0A8B4GC97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

539:CKV94 RS00390
gene id: 539:CKV94_RS00390
uniprot id: A0A8B4G0P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

539:CKV94 RS08510
gene id: 539:CKV94_RS08510
uniprot id: A0A8B4G9C7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

539:CKV94 RS10780
gene id: 539:CKV94_RS10780
uniprot id: A0A1A9RHQ6
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

539:CKV94 RS04460
gene id: 539:CKV94_RS04460
uniprot id: A0A8B4GP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

539:CKV94 RS08585
gene id: 539:CKV94_RS08585
uniprot id: A0A1A9R9Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

539:CKV94 RS08040
gene id: 539:CKV94_RS08040
uniprot id: A0A8B4G7G8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

539:CKV94 RS05495
gene id: 539:CKV94_RS05495
uniprot id: A0A1A9RT12
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS06795
gene id: 539:CKV94_RS06795
uniprot id: A0A1A9RI16
names: Caution
names: Similarity
messages: Belongs to the UPF0145 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS10945
gene id: 539:CKV94_RS10945
uniprot id: A0A8B4GAK0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

539:CKV94 RS02270
gene id: 539:CKV94_RS02270
uniprot id: A0A8B4GE39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS09665
gene id: 539:CKV94_RS09665
uniprot id: A0A8B4GRU8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS03825
gene id: 539:CKV94_RS03825
uniprot id: A0A8B4GEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

539:CKV94 RS09705
gene id: 539:CKV94_RS09705
uniprot id: A0A1A9RCI8
names: Caution
names: Similarity
messages: Belongs to the LOG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05020
gene id: 539:CKV94_RS05020
uniprot id: A0A8B4G5V4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS04270
gene id: 539:CKV94_RS04270
uniprot id: A0A8B4GF38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

539:CKV94 RS04765
gene id: 539:CKV94_RS04765
uniprot id: A0A1A9RDC3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

539:CKV94 RS09900
gene id: 539:CKV94_RS09900
uniprot id: A0A8B4G5R8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

539:CKV94 RS00635
gene id: 539:CKV94_RS00635
uniprot id: A0A8B4GD48
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04715
gene id: 539:CKV94_RS04715
uniprot id: A0A1A9RDM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

539:CKV94 RS10820
gene id: 539:CKV94_RS10820
uniprot id: A0A1A9RU57
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

539:CKV94 RS00520
gene id: 539:CKV94_RS00520
uniprot id: A0A8B4G3S1
names: Similarity
messages: Belongs to the YggT family.

539:CKV94 RS01235
gene id: 539:CKV94_RS01235
uniprot id: A0A8B4G1A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

539:CKV94 RS06610
gene id: 539:CKV94_RS06610
uniprot id: A0A8B4G405
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

539:CKV94 RS06125
gene id: 539:CKV94_RS06125
uniprot id: A0A1A9RJE4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS10160
gene id: 539:CKV94_RS10160
uniprot id: A0A1A9RBJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

539:CKV94 RS08905
gene id: 539:CKV94_RS08905
uniprot id: A0A8B4G595
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

539:CKV94 RS01090
gene id: 539:CKV94_RS01090
uniprot id: A0A8B4G5G1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

539:CKV94 RS01155
gene id: 539:CKV94_RS01155
uniprot id: A0A8B4GDE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

539:CKV94 RS09355
gene id: 539:CKV94_RS09355
uniprot id: A0A8B4GRN6
names: Similarity
messages: Belongs to the CutA family.

539:CKV94 RS02690
gene id: 539:CKV94_RS02690
uniprot id: A0A1A9RG69
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

539:CKV94 RS00030
gene id: 539:CKV94_RS00030
uniprot id: A0A8B4GA67
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

539:CKV94 RS01785
gene id: 539:CKV94_RS01785
uniprot id: A0A8B4G5V1
names: Similarity
messages: Belongs to the hemerythrin family.

539:CKV94 RS00940
gene id: 539:CKV94_RS00940
uniprot id: A0A1A9RI84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

539:CKV94 RS02375
gene id: 539:CKV94_RS02375
uniprot id: A0A8B4GMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

539:CKV94 RS10710
gene id: 539:CKV94_RS10710
uniprot id: A0A1A9RHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS01115
gene id: 539:CKV94_RS01115
uniprot id: A0A8B4GC85
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

539:CKV94 RS00175
gene id: 539:CKV94_RS00175
uniprot id: A0A8B4GBQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS09215
gene id: 539:CKV94_RS09215
uniprot id: A0A8B4GF85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

539:CKV94 RS00875
gene id: 539:CKV94_RS00875
uniprot id: A0A1A9RFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

539:CKV94 RS03785
gene id: 539:CKV94_RS03785
uniprot id: A0A1A9RUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

539:CKV94 RS00700
gene id: 539:CKV94_RS00700
uniprot id: A0A8B4GAL5
names: Similarity
messages: Belongs to the threonine synthase family.

539:CKV94 RS08730
gene id: 539:CKV94_RS08730
uniprot id: A0A1A9RB16
names: Similarity
messages: Belongs to the BolA/IbaG family.

539:CKV94 RS01195
gene id: 539:CKV94_RS01195
uniprot id: A0A1A9RHI7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

539:CKV94 RS02440
gene id: 539:CKV94_RS02440
uniprot id: A0A1A9RNB3
names: Subcellular Location Annotation
messages: Mitochondrion

539:CKV94 RS08455
gene id: 539:CKV94_RS08455
uniprot id: A0A8B4G513
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

539:CKV94 RS09335
gene id: 539:CKV94_RS09335
uniprot id: A0A8B4G9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

539:CKV94 RS06385
gene id: 539:CKV94_RS06385
uniprot id: A0A8B4GF24
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS06270
gene id: 539:CKV94_RS06270
uniprot id: A0A8B4GG45
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

539:CKV94 RS01575
gene id: 539:CKV94_RS01575
uniprot id: A0A8B4G1F0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

539:CKV94 RS04980
gene id: 539:CKV94_RS04980
uniprot id: A0A8B4GP96
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS04305
gene id: 539:CKV94_RS04305
uniprot id: A0A8B4G737
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

539:CKV94 RS02305
gene id: 539:CKV94_RS02305
uniprot id: A0A1A9RPK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03605
gene id: 539:CKV94_RS03605
uniprot id: A0A8B4GNJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS04870
gene id: 539:CKV94_RS04870
uniprot id: A0A8B4GFE7
names: Similarity
messages: Belongs to the IMPACT family.

539:CKV94 RS00485
gene id: 539:CKV94_RS00485
uniprot id: A0A8B4G9U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

539:CKV94 RS09240
gene id: 539:CKV94_RS09240
uniprot id: A0A8B4G9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

539:CKV94 RS10785
gene id: 539:CKV94_RS10785
uniprot id: A0A8B4G675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS09300
gene id: 539:CKV94_RS09300
uniprot id: A0A8B4G825
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

539:CKV94 RS05000
gene id: 539:CKV94_RS05000
uniprot id: A0A8B4G373
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

539:CKV94 RS05675
gene id: 539:CKV94_RS05675
uniprot id: A0A1A9RRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

539:CKV94 RS01385
gene id: 539:CKV94_RS01385
uniprot id: A0A8B4G5M7
names: Similarity
messages: Belongs to the YkuD family.

539:CKV94 RS05735
gene id: 539:CKV94_RS05735
uniprot id: A0A1A9RR12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

539:CKV94 RS05950
gene id: 539:CKV94_RS05950
uniprot id: A0A8B4GDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

539:CKV94 RS08545
gene id: 539:CKV94_RS08545
uniprot id: A0A1A9RF78
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

539:CKV94 RS09265
gene id: 539:CKV94_RS09265
uniprot id: A0A8B4GGT7
names: Similarity
messages: Belongs to the UPF0434 family.

539:CKV94 RS07870
gene id: 539:CKV94_RS07870
uniprot id: A0A1A9RGP2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

539:CKV94 RS03505
gene id: 539:CKV94_RS03505
uniprot id: A0A1A9RU24
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

539:CKV94 RS04160
gene id: 539:CKV94_RS04160
uniprot id: A0A1A9RCP9
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01590
gene id: 539:CKV94_RS01590
uniprot id: A0A1A9RCR5
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

539:CKV94 RS08030
gene id: 539:CKV94_RS08030
uniprot id: A0A1A9RQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

539:CKV94 RS00260
gene id: 539:CKV94_RS00260
uniprot id: A0A8B4G3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

539:CKV94 RS02070
gene id: 539:CKV94_RS02070
uniprot id: A0A8B4GMR7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

539:CKV94 RS05555
gene id: 539:CKV94_RS05555
uniprot id: A0A8B4GD71
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

539:CKV94 RS06875
gene id: 539:CKV94_RS06875
uniprot id: A0A1A9RH68
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS07990
gene id: 539:CKV94_RS07990
uniprot id: A0A8B4G7G0
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS05460
gene id: 539:CKV94_RS05460
uniprot id: A0A1A9RGS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

539:CKV94 RS08990
gene id: 539:CKV94_RS08990
uniprot id: A0A8B4GF37
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS10170
gene id: 539:CKV94_RS10170
uniprot id: A0A1A9RNJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

539:CKV94 RS09620
gene id: 539:CKV94_RS09620
uniprot id: A0A8B4GH18
names: Similarity
messages: Belongs to the peptidase M1 family.

539:CKV94 RS00820
gene id: 539:CKV94_RS00820
uniprot id: A0A8B4G5B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

539:CKV94 RS00860
gene id: 539:CKV94_RS00860
uniprot id: A0A1A9RIC5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

539:CKV94 RS04230
gene id: 539:CKV94_RS04230
uniprot id: A0A8B4GDY7
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00315
gene id: 539:CKV94_RS00315
uniprot id: A0A1A9RGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS09660
gene id: 539:CKV94_RS09660
uniprot id: A0A8B4GI29
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

539:CKV94 RS07110
gene id: 539:CKV94_RS07110
uniprot id: A0A8B4GFH0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

539:CKV94 RS09555
gene id: 539:CKV94_RS09555
uniprot id: A0A8B4GI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

539:CKV94 RS03205
gene id: 539:CKV94_RS03205
uniprot id: A0A1A9RSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

539:CKV94 RS08790
gene id: 539:CKV94_RS08790
uniprot id: A0A8B4GEZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

539:CKV94 RS04090
gene id: 539:CKV94_RS04090
uniprot id: A0A8B4G5G6
names: Similarity
messages: Belongs to the DprA/Smf family.

539:CKV94 RS03765
gene id: 539:CKV94_RS03765
uniprot id: A0A8B4G5B7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS04950
gene id: 539:CKV94_RS04950
uniprot id: A0A1A9RDI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

539:CKV94 RS09990
gene id: 539:CKV94_RS09990
uniprot id: A0A1A9RPS9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

539:CKV94 RS08800
gene id: 539:CKV94_RS08800
uniprot id: A0A8B4G553
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

539:CKV94 RS03665
gene id: 539:CKV94_RS03665
uniprot id: A0A1A9RMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

539:CKV94 RS07855
gene id: 539:CKV94_RS07855
uniprot id: A0A8B4GFZ8
names: Similarity
messages: Belongs to the TrpF family.

539:CKV94 RS08025
gene id: 539:CKV94_RS08025
uniprot id: A0A1A9RGL2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

539:CKV94 RS01140
gene id: 539:CKV94_RS01140
uniprot id: A0A8B4G5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

539:CKV94 RS01725
gene id: 539:CKV94_RS01725
uniprot id: A0A1A9RFL6
names: Subcellular Location Annotation
messages: Cytoplasm

539:CKV94 RS05645
gene id: 539:CKV94_RS05645
uniprot id: A0A1A9RQA7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

539:CKV94 RS01265
gene id: 539:CKV94_RS01265
uniprot id: A0A1A9RGP8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS09290
gene id: 539:CKV94_RS09290
uniprot id: A0A1A9RVB9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

539:CKV94 RS04590
gene id: 539:CKV94_RS04590
uniprot id: A0A1A9RS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

539:CKV94 RS04790
gene id: 539:CKV94_RS04790
uniprot id: A0A1A9RBZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS04545
gene id: 539:CKV94_RS04545
uniprot id: A0A1A9RSQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

539:CKV94 RS05095
gene id: 539:CKV94_RS05095
uniprot id: A0A8B4G389
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

539:CKV94 RS06190
gene id: 539:CKV94_RS06190
uniprot id: A0A1A9RJ69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS09075
gene id: 539:CKV94_RS09075
uniprot id: A0A8B4G5A6
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

539:CKV94 RS04530
gene id: 539:CKV94_RS04530
uniprot id: A0A8B4GC82
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

539:CKV94 RS06210
gene id: 539:CKV94_RS06210
uniprot id: A0A1A9RLG7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

539:CKV94 RS03215
gene id: 539:CKV94_RS03215
uniprot id: A0A1A9RSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

539:CKV94 RS03575
gene id: 539:CKV94_RS03575
uniprot id: A0A1A9RDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

539:CKV94 RS01060
gene id: 539:CKV94_RS01060
uniprot id: A0A8B4GM73
names: Similarity
messages: Belongs to the YjdM family.

539:CKV94 RS06995
gene id: 539:CKV94_RS06995
uniprot id: A0A8B4G6W8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

539:CKV94 RS10105
gene id: 539:CKV94_RS10105
uniprot id: A0A8B4GFD6
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00325
gene id: 539:CKV94_RS00325
uniprot id: A0A1A9RRQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS05725
gene id: 539:CKV94_RS05725
uniprot id: A0A1A9RPW7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

539:CKV94 RS07130
gene id: 539:CKV94_RS07130
uniprot id: A0A1A9RIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS09565
gene id: 539:CKV94_RS09565
uniprot id: A0A8B4GH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

539:CKV94 RS00445
gene id: 539:CKV94_RS00445
uniprot id: A0A8B4G0W6
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

539:CKV94 RS07335
gene id: 539:CKV94_RS07335
uniprot id: A0A8B4GDS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

539:CKV94 RS09715
gene id: 539:CKV94_RS09715
uniprot id: A0A8B4GRW2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

539:CKV94 RS05865
gene id: 539:CKV94_RS05865
uniprot id: A0A8B4G3N2
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00665
gene id: 539:CKV94_RS00665
uniprot id: A0A1A9RSQ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS08065
gene id: 539:CKV94_RS08065
uniprot id: A0A8B4GE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

539:CKV94 RS10875
gene id: 539:CKV94_RS10875
uniprot id: A0A1A9RHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

539:CKV94 RS08150
gene id: 539:CKV94_RS08150
uniprot id: A0A8B4G4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

539:CKV94 RS04145
gene id: 539:CKV94_RS04145
uniprot id: A0A1A9RQ53
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03685
gene id: 539:CKV94_RS03685
uniprot id: A0A1A9RG35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS10410
gene id: 539:CKV94_RS10410
uniprot id: A0A8B4GFJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

539:CKV94 RS06635
gene id: 539:CKV94_RS06635
uniprot id: A0A1A9RS81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

539:CKV94 RS03905
gene id: 539:CKV94_RS03905
uniprot id: A0A8B4G2R4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

539:CKV94 RS05465
gene id: 539:CKV94_RS05465
uniprot id: A0A1A9RTJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05875
gene id: 539:CKV94_RS05875
uniprot id: A0A8B4G7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

539:CKV94 RS07915
gene id: 539:CKV94_RS07915
uniprot id: A0A8B4GEF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

539:CKV94 RS09350
gene id: 539:CKV94_RS09350
uniprot id: A0A1A9RND9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS02435
gene id: 539:CKV94_RS02435
uniprot id: A0A1A9RMK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

539:CKV94 RS07145
gene id: 539:CKV94_RS07145
uniprot id: A0A8B4G701
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

539:CKV94 RS04250
gene id: 539:CKV94_RS04250
uniprot id: A0A8B4G2W3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

539:CKV94 RS08710
gene id: 539:CKV94_RS08710
uniprot id: A0A8B4G9G8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

539:CKV94 RS01850
gene id: 539:CKV94_RS01850
uniprot id: A0A8B4GML7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

539:CKV94 RS09935
gene id: 539:CKV94_RS09935
uniprot id: A0A1A9RCF2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

539:CKV94 RS02040
gene id: 539:CKV94_RS02040
uniprot id: A0A8B4G1P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

539:CKV94 RS00570
gene id: 539:CKV94_RS00570
uniprot id: A0A8B4G3T0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

539:CKV94 RS06790
gene id: 539:CKV94_RS06790
uniprot id: A0A8B4GGE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

539:CKV94 RS05470
gene id: 539:CKV94_RS05470
uniprot id: A0A1A9RTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

539:CKV94 RS04185
gene id: 539:CKV94_RS04185
uniprot id: A0A1A9RDH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03695
gene id: 539:CKV94_RS03695
uniprot id: A0A8B4G2M4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

539:CKV94 RS04085
gene id: 539:CKV94_RS04085
uniprot id: A0A1A9RRM5
names: Similarity
messages: Belongs to the Smg family.

539:CKV94 RS03790
gene id: 539:CKV94_RS03790
uniprot id: A0A8B4GBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

539:CKV94 RS08755
gene id: 539:CKV94_RS08755
uniprot id: A0A1A9RBX4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS02865
gene id: 539:CKV94_RS02865
uniprot id: A0A8B4G266
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

539:CKV94 RS04275
gene id: 539:CKV94_RS04275
uniprot id: A0A8B4GNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

539:CKV94 RS09650
gene id: 539:CKV94_RS09650
uniprot id: A0A1A9RJG6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

539:CKV94 RS02975
gene id: 539:CKV94_RS02975
uniprot id: A0A8B4G6G4
names: Similarity
messages: Belongs to the opacity porin family.

539:CKV94 RS06885
gene id: 539:CKV94_RS06885
uniprot id: A0A8B4GFN0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

539:CKV94 RS10280
gene id: 539:CKV94_RS10280
uniprot id: A0A8B4G8I9
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01290
gene id: 539:CKV94_RS01290
uniprot id: A0A1A9RUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

539:CKV94 RS04725
gene id: 539:CKV94_RS04725
uniprot id: A0A8B4GP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

539:CKV94 RS04810
gene id: 539:CKV94_RS04810
uniprot id: A0A1A9RDB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

539:CKV94 RS04490
gene id: 539:CKV94_RS04490
uniprot id: A0A8B4G773
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS08555
gene id: 539:CKV94_RS08555
uniprot id: A0A8B4G533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

539:CKV94 RS02010
gene id: 539:CKV94_RS02010
uniprot id: A0A1A9RDM9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS00145
gene id: 539:CKV94_RS00145
uniprot id: A0A1A9RH04
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

539:CKV94 RS04520
gene id: 539:CKV94_RS04520
uniprot id: A0A1A9RRP9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03070
gene id: 539:CKV94_RS03070
uniprot id: A0A1A9RFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

539:CKV94 RS03530
gene id: 539:CKV94_RS03530
uniprot id: A0A1A9RU65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

539:CKV94 RS00160
gene id: 539:CKV94_RS00160
uniprot id: A0A1A9RGN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

539:CKV94 RS01740
gene id: 539:CKV94_RS01740
uniprot id: A0A8B4GCZ7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

539:CKV94 RS01950
gene id: 539:CKV94_RS01950
uniprot id: A0A8B4GMP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

539:CKV94 RS00070
gene id: 539:CKV94_RS00070
uniprot id: A0A1A9RFB0
names: Caution
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03855
gene id: 539:CKV94_RS03855
uniprot id: A0A8B4G2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

539:CKV94 RS07010
gene id: 539:CKV94_RS07010
uniprot id: A0A8B4GQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

539:CKV94 RS08830
gene id: 539:CKV94_RS08830
uniprot id: A0A8B4GRC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

539:CKV94 RS00400
gene id: 539:CKV94_RS00400
uniprot id: A0A8B4G522
names: Similarity
messages: Belongs to the phosphohexose mutase family.

539:CKV94 RS07255
gene id: 539:CKV94_RS07255
uniprot id: A0A8B4GFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

539:CKV94 RS07865
gene id: 539:CKV94_RS07865
uniprot id: A0A1A9RPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS06170
gene id: 539:CKV94_RS06170
uniprot id: A0A1A9RIT5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS04585
gene id: 539:CKV94_RS04585
uniprot id: A0A8B4GCA4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

539:CKV94 RS06480
gene id: 539:CKV94_RS06480
uniprot id: A0A8B4GG93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

539:CKV94 RS08145
gene id: 539:CKV94_RS08145
uniprot id: A0A8B4G4T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

539:CKV94 RS08495
gene id: 539:CKV94_RS08495
uniprot id: A0A8B4GEH0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

539:CKV94 RS07350
gene id: 539:CKV94_RS07350
uniprot id: A0A8B4G4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

539:CKV94 RS00535
gene id: 539:CKV94_RS00535
uniprot id: A0A1A9RIZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03845
gene id: 539:CKV94_RS03845
uniprot id: A0A8B4GBT5
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS00615
gene id: 539:CKV94_RS00615
uniprot id: A0A8B4G0Z7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

539:CKV94 RS02585
gene id: 539:CKV94_RS02585
uniprot id: A0A8B4GBL6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

539:CKV94 RS02020
gene id: 539:CKV94_RS02020
uniprot id: A0A8B4GMQ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

539:CKV94 RS06470
gene id: 539:CKV94_RS06470
uniprot id: A0A1A9RJV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

539:CKV94 RS09345
gene id: 539:CKV94_RS09345
uniprot id: A0A1A9RNE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

539:CKV94 RS05005
gene id: 539:CKV94_RS05005
uniprot id: A0A8B4G3A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

539:CKV94 RS10760
gene id: 539:CKV94_RS10760
uniprot id: A0A1A9RH81
names: Similarity
messages: Belongs to the SAICAR synthetase family.

539:CKV94 RS01445
gene id: 539:CKV94_RS01445
uniprot id: A0A8B4G482
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01210
gene id: 539:CKV94_RS01210
uniprot id: A0A1A9RB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

539:CKV94 RS07270
gene id: 539:CKV94_RS07270
uniprot id: A0A8B4GQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS01935
gene id: 539:CKV94_RS01935
uniprot id: A0A8B4G5X6
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

539:CKV94 RS02920
gene id: 539:CKV94_RS02920
uniprot id: A0A1A9RNQ2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

539:CKV94 RS08955
gene id: 539:CKV94_RS08955
uniprot id: A0A8B4G5A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

539:CKV94 RS04595
gene id: 539:CKV94_RS04595
uniprot id: A0A1A9RRU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS09640
gene id: 539:CKV94_RS09640
uniprot id: A0A8B4G5N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

539:CKV94 RS04835
gene id: 539:CKV94_RS04835
uniprot id: A0A8B4GCS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

539:CKV94 RS06140
gene id: 539:CKV94_RS06140
uniprot id: A0A1A9RL50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05195
gene id: 539:CKV94_RS05195
uniprot id: A0A8B4GCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

539:CKV94 RS04385
gene id: 539:CKV94_RS04385
uniprot id: A0A8B4GC22
names: Similarity
messages: Belongs to the nitroreductase family.

539:CKV94 RS10585
gene id: 539:CKV94_RS10585
uniprot id: A0A8B4G8Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

539:CKV94 RS07745
gene id: 539:CKV94_RS07745
uniprot id: A0A8B4GED2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

539:CKV94 RS00925
gene id: 539:CKV94_RS00925
uniprot id: A0A240CHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

539:CKV94 RS10920
gene id: 539:CKV94_RS10920
uniprot id: A0A1A9RGW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS10480
gene id: 539:CKV94_RS10480
uniprot id: A0A8B4GHF6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

539:CKV94 RS05680
gene id: 539:CKV94_RS05680
uniprot id: A0A1A9RGW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

539:CKV94 RS09590
gene id: 539:CKV94_RS09590
uniprot id: A0A1A9RM39
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

539:CKV94 RS05480
gene id: 539:CKV94_RS05480
uniprot id: A0A1A9RQT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

539:CKV94 RS04095
gene id: 539:CKV94_RS04095
uniprot id: A0A1A9RSW8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

539:CKV94 RS08070
gene id: 539:CKV94_RS08070
uniprot id: A0A8B4G4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

539:CKV94 RS06025
gene id: 539:CKV94_RS06025
uniprot id: A0A8B4G818
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS03645
gene id: 539:CKV94_RS03645
uniprot id: A0A8B4GDX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

539:CKV94 RS01530
gene id: 539:CKV94_RS01530
uniprot id: A0A8B4G1F6
names: Similarity
messages: Belongs to the UPF0102 family.

539:CKV94 RS04645
gene id: 539:CKV94_RS04645
uniprot id: A0A1A9RAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

539:CKV94 RS08765
gene id: 539:CKV94_RS08765
uniprot id: A0A8B4GGL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

539:CKV94 RS10285
gene id: 539:CKV94_RS10285
uniprot id: A0A1A9RCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS03670
gene id: 539:CKV94_RS03670
uniprot id: A0A8B4GNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS00975
gene id: 539:CKV94_RS00975
uniprot id: A0A8B4G110
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS09610
gene id: 539:CKV94_RS09610
uniprot id: A0A1A9RJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

539:CKV94 RS06835
gene id: 539:CKV94_RS06835
uniprot id: A0A1A9RKM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

539:CKV94 RS10530
gene id: 539:CKV94_RS10530
uniprot id: A0A8B4GHG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

539:CKV94 RS01720
gene id: 539:CKV94_RS01720
uniprot id: A0A8B4GAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

539:CKV94 RS06010
gene id: 539:CKV94_RS06010
uniprot id: A0A8B4GD04
names: Similarity
messages: Belongs to the UPF0246 family.

539:CKV94 RS01615
gene id: 539:CKV94_RS01615
uniprot id: A0A1A9RD57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS03260
gene id: 539:CKV94_RS03260
uniprot id: A0A8B4GEL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

539:CKV94 RS00740
gene id: 539:CKV94_RS00740
uniprot id: A0A1A9RIA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

539:CKV94 RS03840
gene id: 539:CKV94_RS03840
uniprot id: A0A1A9RUI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

539:CKV94 RS00600
gene id: 539:CKV94_RS00600
uniprot id: A0A1A9RF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Cell outer membrane
messages: Membrane

539:CKV94 RS04635
gene id: 539:CKV94_RS04635
uniprot id: A0A8B4GCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS05805
gene id: 539:CKV94_RS05805
uniprot id: A0A8B4GDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

539:CKV94 RS07005
gene id: 539:CKV94_RS07005
uniprot id: A0A8B4GGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

539:CKV94 RS01065
gene id: 539:CKV94_RS01065
uniprot id: A0A8B4GC76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

539:CKV94 RS06410
gene id: 539:CKV94_RS06410
uniprot id: A0A8B4G894
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

539:CKV94 RS02805
gene id: 539:CKV94_RS02805
uniprot id: A0A1A9RFW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS06680
gene id: 539:CKV94_RS06680
uniprot id: A0A8B4GFJ4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS09700
gene id: 539:CKV94_RS09700
uniprot id: A0A8B4GH25
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

539:CKV94 RS01000
gene id: 539:CKV94_RS01000
uniprot id: A0A8B4G3Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

539:CKV94 RS06675
gene id: 539:CKV94_RS06675
uniprot id: A0A8B4G8F4
names: Similarity
messages: Belongs to the SlyX family.

539:CKV94 RS10790
gene id: 539:CKV94_RS10790
uniprot id: A0A1A9RG25
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

539:CKV94 RS00095
gene id: 539:CKV94_RS00095
uniprot id: A0A8B4G0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

539:CKV94 RS00620
gene id: 539:CKV94_RS00620
uniprot id: A0A8B4G561
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

539:CKV94 RS10770
gene id: 539:CKV94_RS10770
uniprot id: A0A8B4GG58
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

539:CKV94 RS00660
gene id: 539:CKV94_RS00660
uniprot id: A0A1A9RHG4
names: Similarity
messages: Belongs to the thioredoxin family.

539:CKV94 RS00305
gene id: 539:CKV94_RS00305
uniprot id: A0A1A9RH28
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

539:CKV94 RS04630
gene id: 539:CKV94_RS04630
uniprot id: A0A1A9RH37
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05855
gene id: 539:CKV94_RS05855
uniprot id: A0A8B4GDB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

539:CKV94 RS07310
gene id: 539:CKV94_RS07310
uniprot id: A0A8B4G735
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS06950
gene id: 539:CKV94_RS06950
uniprot id: A0A1A9RKP4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS06330
gene id: 539:CKV94_RS06330
uniprot id: A0A8B4GF10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

539:CKV94 RS01920
gene id: 539:CKV94_RS01920
uniprot id: A0A1A9RBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

539:CKV94 RS07810
gene id: 539:CKV94_RS07810
uniprot id: A0A8B4GEE2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

539:CKV94 RS01305
gene id: 539:CKV94_RS01305
uniprot id: A0A8B4GMB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

539:CKV94 RS06890
gene id: 539:CKV94_RS06890
uniprot id: A0A1A9RJE7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

539:CKV94 RS10045
gene id: 539:CKV94_RS10045
uniprot id: A0A8B4GHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

539:CKV94 RS08185
gene id: 539:CKV94_RS08185
uniprot id: A0A8B4GG63
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

539:CKV94 RS10650
gene id: 539:CKV94_RS10650
uniprot id: A0A1A9RBT7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

539:CKV94 RS05665
gene id: 539:CKV94_RS05665
uniprot id: A0A1A9RM96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

539:CKV94 RS02330
gene id: 539:CKV94_RS02330
uniprot id: A0A1A9RNF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

539:CKV94 RS03435
gene id: 539:CKV94_RS03435
uniprot id: A0A8B4G564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

539:CKV94 RS06530
gene id: 539:CKV94_RS06530
uniprot id: A0A8B4G6M3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

539:CKV94 RS09740
gene id: 539:CKV94_RS09740
uniprot id: A0A8B4G6M3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

539:CKV94 RS03320
gene id: 539:CKV94_RS03320
uniprot id: A0A1A9RCU4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

539:CKV94 RS05535
gene id: 539:CKV94_RS05535
uniprot id: A0A1A9RHI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS02940
gene id: 539:CKV94_RS02940
uniprot id: A0A1A9RPF8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

539:CKV94 RS06360
gene id: 539:CKV94_RS06360
uniprot id: A0A8B4G881
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS07100
gene id: 539:CKV94_RS07100
uniprot id: A0A8B4GGK9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

539:CKV94 RS10035
gene id: 539:CKV94_RS10035
uniprot id: A0A1A9RLN1
names: Subcellular Location Annotation
messages: Cytoplasm

539:CKV94 RS03220
gene id: 539:CKV94_RS03220
uniprot id: A0A1A9RRP3
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS05475
gene id: 539:CKV94_RS05475
uniprot id: A0A1A9RS76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

539:CKV94 RS01565
gene id: 539:CKV94_RS01565
uniprot id: A0A8B4GB27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

539:CKV94 RS06090
gene id: 539:CKV94_RS06090
uniprot id: A0A1A9RKR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

539:CKV94 RS03185
gene id: 539:CKV94_RS03185
uniprot id: A0A8B4G2C6
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS06820
gene id: 539:CKV94_RS06820
uniprot id: A0A1A9RQF2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

539:CKV94 RS01165
gene id: 539:CKV94_RS01165
uniprot id: A0A8B4GC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

539:CKV94 RS03615
gene id: 539:CKV94_RS03615
uniprot id: A0A1A9RE67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05545
gene id: 539:CKV94_RS05545
uniprot id: A0A1A9RQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

539:CKV94 RS10635
gene id: 539:CKV94_RS10635
uniprot id: A0A1A9R9X0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

539:CKV94 RS00805
gene id: 539:CKV94_RS00805
uniprot id: A0A1A9RFN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS00780
gene id: 539:CKV94_RS00780
uniprot id: A0A8B4G3W1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

539:CKV94 RS10870
gene id: 539:CKV94_RS10870
uniprot id: A0A1A9RGJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

539:CKV94 RS02685
gene id: 539:CKV94_RS02685
uniprot id: A0A1A9REZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

539:CKV94 RS08055
gene id: 539:CKV94_RS08055
uniprot id: A0A1A9RHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

539:CKV94 RS09950
gene id: 539:CKV94_RS09950
uniprot id: A0A8B4GFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

539:CKV94 RS07225
gene id: 539:CKV94_RS07225
uniprot id: A0A8B4GE32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

539:CKV94 RS01495
gene id: 539:CKV94_RS01495
uniprot id: A0A8B4G491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

539:CKV94 RS02680
gene id: 539:CKV94_RS02680
uniprot id: A0A1A9RDK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

539:CKV94 RS10205
gene id: 539:CKV94_RS10205
uniprot id: A0A8B4GFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

539:CKV94 RS03675
gene id: 539:CKV94_RS03675
uniprot id: A0A8B4GDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

539:CKV94 RS05415
gene id: 539:CKV94_RS05415
uniprot id: A0A1A9RGB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

539:CKV94 RS08205
gene id: 539:CKV94_RS08205
uniprot id: A0A8B4G4W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

539:CKV94 RS00730
gene id: 539:CKV94_RS00730
uniprot id: A0A8B4G3V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

539:CKV94 RS06105
gene id: 539:CKV94_RS06105
uniprot id: A0A1A9RPQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

539:CKV94 RS01540
gene id: 539:CKV94_RS01540
uniprot id: A0A8B4GCW4
names: Similarity
messages: Belongs to the YkuD family.

539:CKV94 RS06500
gene id: 539:CKV94_RS06500
uniprot id: A0A8B4GDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

539:CKV94 RS09510
gene id: 539:CKV94_RS09510
uniprot id: A0A8B4GRS0
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

539:CKV94 RS08940
gene id: 539:CKV94_RS08940
uniprot id: A0A8B4GF28
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

539:CKV94 RS08550
gene id: 539:CKV94_RS08550
uniprot id: A0A1A9RBU6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

539:CKV94 RS03190
gene id: 539:CKV94_RS03190
uniprot id: A0A8B4G6K1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

539:CKV94 RS03400
gene id: 539:CKV94_RS03400
uniprot id: A0A1A9RSV4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

539:CKV94 RS05530
gene id: 539:CKV94_RS05530
uniprot id: A0A1A9RRN6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

539:CKV94 RS05190
gene id: 539:CKV94_RS05190
uniprot id: A0A8B4GEH2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

539:CKV94 RS08515
gene id: 539:CKV94_RS08515
uniprot id: A0A8B4GGH4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

539:CKV94 RS00525
gene id: 539:CKV94_RS00525
uniprot id: A0A8B4GD27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

539:CKV94 RS10555
gene id: 539:CKV94_RS10555
uniprot id: A0A8B4GG23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS05755
gene id: 539:CKV94_RS05755
uniprot id: A0A1A9RQA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

539:CKV94 RS09725
gene id: 539:CKV94_RS09725
uniprot id: A0A8B4GFI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS05710
gene id: 539:CKV94_RS05710
uniprot id: A0A1A9RRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

539:CKV94 RS01055
gene id: 539:CKV94_RS01055
uniprot id: A0A8B4GDB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS03815
gene id: 539:CKV94_RS03815
uniprot id: A0A1A9RTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

539:CKV94 RS10080
gene id: 539:CKV94_RS10080
uniprot id: A0A1A9RJ73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

539:CKV94 RS05905
gene id: 539:CKV94_RS05905
uniprot id: A0A8B4GCY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS00265
gene id: 539:CKV94_RS00265
uniprot id: A0A1A9RRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS02315
gene id: 539:CKV94_RS02315
uniprot id: A0A8B4G4Q1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

539:CKV94 RS07485
gene id: 539:CKV94_RS07485
uniprot id: A0A8B4G4G9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS09865
gene id: 539:CKV94_RS09865
uniprot id: A0A8B4G8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

539:CKV94 RS08130
gene id: 539:CKV94_RS08130
uniprot id: A0A1A9RTG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

539:CKV94 RS01410
gene id: 539:CKV94_RS01410
uniprot id: A0A8B4GCE0
names: Subunit
messages: Homodimer.

539:CKV94 RS00235
gene id: 539:CKV94_RS00235
uniprot id: A0A8B4G9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS10955
gene id: 539:CKV94_RS10955
uniprot id: A0A1A9RCX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

539:CKV94 RS00170
gene id: 539:CKV94_RS00170
uniprot id: A0A8B4GLN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

539:CKV94 RS05380
gene id: 539:CKV94_RS05380
uniprot id: A0A8B4GPH0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

539:CKV94 RS06770
gene id: 539:CKV94_RS06770
uniprot id: A0A1A9RKT9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

539:CKV94 RS00425
gene id: 539:CKV94_RS00425
uniprot id: A0A8B4GBW0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

539:CKV94 RS02830
gene id: 539:CKV94_RS02830
uniprot id: A0A8B4GDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

539:CKV94 RS00810
gene id: 539:CKV94_RS00810
uniprot id: A0A8B4G0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS07925
gene id: 539:CKV94_RS07925
uniprot id: A0A8B4G4P9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

539:CKV94 RS02950
gene id: 539:CKV94_RS02950
uniprot id: A0A1A9RES6
names: Similarity
messages: Belongs to the peptidase S66 family.

539:CKV94 RS01840
gene id: 539:CKV94_RS01840
uniprot id: A0A8B4G4F5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS07895
gene id: 539:CKV94_RS07895
uniprot id: A0A8B4GH53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

539:CKV94 RS01525
gene id: 539:CKV94_RS01525
uniprot id: A0A1A9RKV1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

539:CKV94 RS06445
gene id: 539:CKV94_RS06445
uniprot id: A0A8B4GDM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS06130
gene id: 539:CKV94_RS06130
uniprot id: A0A1A9RMB5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS09270
gene id: 539:CKV94_RS09270
uniprot id: A0A8B4GF95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

539:CKV94 RS04620
gene id: 539:CKV94_RS04620
uniprot id: A0A8B4GP31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

539:CKV94 RS02420
gene id: 539:CKV94_RS02420
uniprot id: A0A8B4GE67
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

539:CKV94 RS07330
gene id: 539:CKV94_RS07330
uniprot id: A0A8B4GE49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

539:CKV94 RS03075
gene id: 539:CKV94_RS03075
uniprot id: A0A8B4G2A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

539:CKV94 RS01470
gene id: 539:CKV94_RS01470
uniprot id: A0A1A9REW0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

539:CKV94 RS10730
gene id: 539:CKV94_RS10730
uniprot id: A0A8B4G679
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

539:CKV94 RS08665
gene id: 539:CKV94_RS08665
uniprot id: A0A1A9RE99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

539:CKV94 RS04710
gene id: 539:CKV94_RS04710
uniprot id: A0A8B4G5Q7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

539:CKV94 RS07160
gene id: 539:CKV94_RS07160
uniprot id: A0A8B4GFI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

539:CKV94 RS02600
gene id: 539:CKV94_RS02600
uniprot id: A0A1A9RBT8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

539:CKV94 RS06730
gene id: 539:CKV94_RS06730
uniprot id: A0A1A9RN76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

539:CKV94 RS07875
gene id: 539:CKV94_RS07875
uniprot id: A0A1A9RPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

539:CKV94 RS02515
gene id: 539:CKV94_RS02515
uniprot id: A0A8B4G4S6
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS08005
gene id: 539:CKV94_RS08005
uniprot id: A0A1A9RQM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

539:CKV94 RS05260
gene id: 539:CKV94_RS05260
uniprot id: A0A8B4G3E8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

539:CKV94 RS09655
gene id: 539:CKV94_RS09655
uniprot id: A0A8B4G884
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

539:CKV94 RS03880
gene id: 539:CKV94_RS03880
uniprot id: A0A8B4GNP7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

539:CKV94 RS03065
gene id: 539:CKV94_RS03065
uniprot id: A0A8B4GBB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

539:CKV94 RS09625
gene id: 539:CKV94_RS09625
uniprot id: A0A8B4GFG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS06120
gene id: 539:CKV94_RS06120
uniprot id: A0A1A9RJ78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS00630
gene id: 539:CKV94_RS00630
uniprot id: A0A8B4G3T8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS10510
gene id: 539:CKV94_RS10510
uniprot id: A0A1A9RUB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

539:CKV94 RS09205
gene id: 539:CKV94_RS09205
uniprot id: A0A8B4GRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

539:CKV94 RS04210
gene id: 539:CKV94_RS04210
uniprot id: A0A1A9RTH9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

539:CKV94 RS02335
gene id: 539:CKV94_RS02335
uniprot id: A0A8B4GBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

539:CKV94 RS03350
gene id: 539:CKV94_RS03350
uniprot id: A0A8B4GBZ7
names: Similarity
messages: Belongs to the MlaA family.

539:CKV94 RS01320
gene id: 539:CKV94_RS01320
uniprot id: A0A1A9RGQ7
names: Similarity
messages: Belongs to the peptidase S41A family.

539:CKV94 RS08795
gene id: 539:CKV94_RS08795
uniprot id: A0A8B4GEN7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

539:CKV94 RS09005
gene id: 539:CKV94_RS09005
uniprot id: A0A8B4G5B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

539:CKV94 RS06305
gene id: 539:CKV94_RS06305
uniprot id: A0A8B4G869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

539:CKV94 RS00955
gene id: 539:CKV94_RS00955
uniprot id: A0A1A9RFQ2
names: Similarity
messages: Belongs to the Dps family.

539:CKV94 RS10265
gene id: 539:CKV94_RS10265
uniprot id: A0A8B4G5Y3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

539:CKV94 RS09635
gene id: 539:CKV94_RS09635
uniprot id: A0A8B4G5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

539:CKV94 RS06080
gene id: 539:CKV94_RS06080
uniprot id: A0A1A9RMN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

539:CKV94 RS01070
gene id: 539:CKV94_RS01070
uniprot id: A0A8B4GAT9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

539:CKV94 RS10320
gene id: 539:CKV94_RS10320
uniprot id: A0A8B4GA93
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

539:CKV94 RS05100
gene id: 539:CKV94_RS05100
uniprot id: A0A8B4G3C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

539:CKV94 RS03850
gene id: 539:CKV94_RS03850
uniprot id: A0A8B4G2M8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

539:CKV94 RS07490
gene id: 539:CKV94_RS07490
uniprot id: A0A1A9RI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

539:CKV94 RS05155
gene id: 539:CKV94_RS05155
uniprot id: A0A1A9RG16
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

539:CKV94 RS07630
gene id: 539:CKV94_RS07630
uniprot id: A0A8B4GEB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

539:CKV94 RS07500
gene id: 539:CKV94_RS07500
uniprot id: A0A8B4GFZ6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

539:CKV94 RS07980
gene id: 539:CKV94_RS07980
uniprot id: A0A1A9RGM1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

539:CKV94 RS06095
gene id: 539:CKV94_RS06095
uniprot id: A0A1A9RLJ0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

539:CKV94 RS03470
gene id: 539:CKV94_RS03470
uniprot id: A0A1A9RU80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

539:CKV94 RS07800
gene id: 539:CKV94_RS07800
uniprot id: A0A8B4GQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

539:CKV94 RS05625
gene id: 539:CKV94_RS05625
uniprot id: A0A8B4GD78
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

539:CKV94 RS03690
gene id: 539:CKV94_RS03690
uniprot id: A0A1A9RET3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

539:CKV94 RS07325
gene id: 539:CKV94_RS07325
uniprot id: A0A8B4GFM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS02015
gene id: 539:CKV94_RS02015
uniprot id: A0A1A9REK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

539:CKV94 RS04825
gene id: 539:CKV94_RS04825
uniprot id: A0A1A9RDP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

539:CKV94 RS02840
gene id: 539:CKV94_RS02840
uniprot id: A0A8B4GED8
names: Similarity
messages: Belongs to the TrpC family.

539:CKV94 RS02275
gene id: 539:CKV94_RS02275
uniprot id: A0A8B4GMW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

539:CKV94 RS04100
gene id: 539:CKV94_RS04100
uniprot id: A0A1A9RRM3
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

539:CKV94 RS07545
gene id: 539:CKV94_RS07545
uniprot id: A0A1A9RJS8
names: Similarity
messages: Belongs to the MoaD family.

539:CKV94 RS02570
gene id: 539:CKV94_RS02570
uniprot id: A0A8B4GE96
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS10515
gene id: 539:CKV94_RS10515
uniprot id: A0A1A9RUP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

539:CKV94 RS10685
gene id: 539:CKV94_RS10685
uniprot id: A0A1A9RHD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05925
gene id: 539:CKV94_RS05925
uniprot id: A0A8B4GF64
names: Similarity
messages: Belongs to the UPF0310 family.

539:CKV94 RS00835
gene id: 539:CKV94_RS00835
uniprot id: A0A8B4GD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Membrane

539:CKV94 RS10660
gene id: 539:CKV94_RS10660
uniprot id: A0A8B4GHP1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

539:CKV94 RS05145
gene id: 539:CKV94_RS05145
uniprot id: A0A1A9RRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS02695
gene id: 539:CKV94_RS02695
uniprot id: A0A1A9RGA6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

539:CKV94 RS02745
gene id: 539:CKV94_RS02745
uniprot id: A0A1A9RDJ1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

539:CKV94 RS04800
gene id: 539:CKV94_RS04800
uniprot id: A0A1A9REJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

539:CKV94 RS00330
gene id: 539:CKV94_RS00330
uniprot id: A0A1A9RGR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

539:CKV94 RS00490
gene id: 539:CKV94_RS00490
uniprot id: A0A8B4G0R0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

539:CKV94 RS07135
gene id: 539:CKV94_RS07135
uniprot id: A0A8B4G8P4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

539:CKV94 RS05990
gene id: 539:CKV94_RS05990
uniprot id: A0A8B4GG06
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

539:CKV94 RS03900
gene id: 539:CKV94_RS03900
uniprot id: A0A8B4G2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

539:CKV94 RS01130
gene id: 539:CKV94_RS01130
uniprot id: A0A8B4G147
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

539:CKV94 RS03370
gene id: 539:CKV94_RS03370
uniprot id: A0A8B4G6N9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

539:CKV94 RS10525
gene id: 539:CKV94_RS10525
uniprot id: A0A8B4GAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

539:CKV94 RS04525
gene id: 539:CKV94_RS04525
uniprot id: A0A1A9RS44
names: Similarity
messages: Belongs to the barstar family.

539:CKV94 RS07820
gene id: 539:CKV94_RS07820
uniprot id: A0A8B4G4M4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS06380
gene id: 539:CKV94_RS06380
uniprot id: A0A8B4GPZ2
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01780
gene id: 539:CKV94_RS01780
uniprot id: A0A1A9RBK4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

539:CKV94 RS06605
gene id: 539:CKV94_RS06605
uniprot id: A0A1A9RI47
names: Subcellular Location Annotation
messages: Cytoplasm

539:CKV94 RS05360
gene id: 539:CKV94_RS05360
uniprot id: A0A1A9RSY3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

539:CKV94 RS05965
gene id: 539:CKV94_RS05965
uniprot id: A0A8B4G3S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS08310
gene id: 539:CKV94_RS08310
uniprot id: A0A8B4G4Y2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homodimer.

539:CKV94 RS00280
gene id: 539:CKV94_RS00280
uniprot id: A0A1A9RRB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

539:CKV94 RS01435
gene id: 539:CKV94_RS01435
uniprot id: A0A8B4G5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

539:CKV94 RS04850
gene id: 539:CKV94_RS04850
uniprot id: A0A1A9REI7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

539:CKV94 RS01605
gene id: 539:CKV94_RS01605
uniprot id: A0A8B4GMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

539:CKV94 RS08920
gene id: 539:CKV94_RS08920
uniprot id: A0A8B4G7W0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

539:CKV94 RS07650
gene id: 539:CKV94_RS07650
uniprot id: A0A1A9RID6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

539:CKV94 RS08320
gene id: 539:CKV94_RS08320
uniprot id: A0A8B4GGE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

539:CKV94 RS06110
gene id: 539:CKV94_RS06110
uniprot id: A0A1A9RJM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

539:CKV94 RS02200
gene id: 539:CKV94_RS02200
uniprot id: A0A8B4G1U3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

539:CKV94 RS01440
gene id: 539:CKV94_RS01440
uniprot id: A0A8B4GCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS04605
gene id: 539:CKV94_RS04605
uniprot id: A0A1A9RGB5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

539:CKV94 RS10335
gene id: 539:CKV94_RS10335
uniprot id: A0A8B4GII5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

539:CKV94 RS04770
gene id: 539:CKV94_RS04770
uniprot id: A0A1A9RCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

539:CKV94 RS07360
gene id: 539:CKV94_RS07360
uniprot id: A0A1A9RKC5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

539:CKV94 RS07890
gene id: 539:CKV94_RS07890
uniprot id: A0A8B4G7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

539:CKV94 RS02425
gene id: 539:CKV94_RS02425
uniprot id: A0A8B4GMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

539:CKV94 RS06580
gene id: 539:CKV94_RS06580
uniprot id: A0A8B4G6N3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

539:CKV94 RS07665
gene id: 539:CKV94_RS07665
uniprot id: A0A1A9RTZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

539:CKV94 RS10460
gene id: 539:CKV94_RS10460
uniprot id: A0A1A9RH32
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS01095
gene id: 539:CKV94_RS01095
uniprot id: A0A8B4GCN1
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

539:CKV94 RS02790
gene id: 539:CKV94_RS02790
uniprot id: A0A8B4GED5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

539:CKV94 RS05440
gene id: 539:CKV94_RS05440
uniprot id: A0A8B4GPI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

539:CKV94 RS09730
gene id: 539:CKV94_RS09730
uniprot id: A0A1A9RLI2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

539:CKV94 RS06215
gene id: 539:CKV94_RS06215
uniprot id: A0A1A9RLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

539:CKV94 RS05730
gene id: 539:CKV94_RS05730
uniprot id: A0A1A9RGD6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS05835
gene id: 539:CKV94_RS05835
uniprot id: A0A8B4G698
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS10965
gene id: 539:CKV94_RS10965
uniprot id: A0A8B4GIV9
names: Similarity
messages: Belongs to the GSP E family.

539:CKV94 RS07435
gene id: 539:CKV94_RS07435
uniprot id: A0A8B4GE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

539:CKV94 RS06775
gene id: 539:CKV94_RS06775
uniprot id: A0A8B4G8H6
names: Subunit
messages: Homodimer.

539:CKV94 RS08855
gene id: 539:CKV94_RS08855
uniprot id: A0A8B4G586
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

539:CKV94 RS02925
gene id: 539:CKV94_RS02925
uniprot id: A0A1A9RDX8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

539:CKV94 RS06465
gene id: 539:CKV94_RS06465
uniprot id: A0A1A9RIN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

539:CKV94 RS08085
gene id: 539:CKV94_RS08085
uniprot id: A0A1A9RPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS07495
gene id: 539:CKV94_RS07495
uniprot id: A0A1A9RJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

539:CKV94 RS00180
gene id: 539:CKV94_RS00180
uniprot id: A0A8B4GAA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

539:CKV94 RS02505
gene id: 539:CKV94_RS02505
uniprot id: A0A1A9RNN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

539:CKV94 RS09035
gene id: 539:CKV94_RS09035
uniprot id: A0A8B4GGN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

539:CKV94 RS02895
gene id: 539:CKV94_RS02895
uniprot id: A0A8B4GD79
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

539:CKV94 RS00125
gene id: 539:CKV94_RS00125
uniprot id: A0A8B4GLM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

539:CKV94 RS10795
gene id: 539:CKV94_RS10795
uniprot id: A0A1A9RI57
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

539:CKV94 RS05785
gene id: 539:CKV94_RS05785
uniprot id: A0A8B4GF30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

539:CKV94 RS05635
gene id: 539:CKV94_RS05635
uniprot id: A0A8B4G3J5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

539:CKV94 RS06630
gene id: 539:CKV94_RS06630
uniprot id: A0A1A9RH09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

539:CKV94 RS08010
gene id: 539:CKV94_RS08010
uniprot id: A0A8B4GEH4
names: Subcellular Location Annotation
messages: Membrane

539:CKV94 RS01535
gene id: 539:CKV94_RS01535
uniprot id: A0A8B4G5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

539:CKV94 RS02815
gene id: 539:CKV94_RS02815
uniprot id: A0A1A9RDU2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

539:CKV94 RS00595
gene id: 539:CKV94_RS00595
uniprot id: A0A8B4GBZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

539:CKV94 RS07020
gene id: 539:CKV94_RS07020
uniprot id: A0A8B4GDY9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

539:CKV94 RS00020
gene id: 539:CKV94_RS00020
uniprot id: A0A8B4GLL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

539:CKV94 RS08580
gene id: 539:CKV94_RS08580
uniprot id: A0A8B4GR75
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

539:CKV94 RS02295
gene id: 539:CKV94_RS02295
uniprot id: A0A8B4G1U7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

539:CKV94 RS09365
gene id: 539:CKV94_RS09365
uniprot id: A0A8B4GFB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.