53346:EM4838 RS11155
gene id: 53346:EM4838_RS11155
uniprot id: A0A1L8UTN8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS03980
gene id: 53346:EM4838_RS03980
uniprot id: A0A242KY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

53346:EM4838 RS12950
gene id: 53346:EM4838_RS12950
uniprot id: A0A1A6G7W8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS12445
gene id: 53346:EM4838_RS12445
uniprot id: A0A1A6G5H6
names: Similarity
messages: Belongs to the UPF0213 family.

53346:EM4838 RS03440
gene id: 53346:EM4838_RS03440
uniprot id: A0A2K8TD41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

53346:EM4838 RS14165
gene id: 53346:EM4838_RS14165
uniprot id: A0A1A6GAE8
names: Similarity
messages: Belongs to the ParB family.

53346:EM4838 RS03010
gene id: 53346:EM4838_RS03010
uniprot id: A0A2K8TCW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

53346:EM4838 RS01480
gene id: 53346:EM4838_RS01480
uniprot id: A0A2K8TC87
names: Similarity
messages: Belongs to the aldose epimerase family.

53346:EM4838 RS11045
gene id: 53346:EM4838_RS11045
uniprot id: A0A2K8TH45
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

53346:EM4838 RS07660
gene id: 53346:EM4838_RS07660
uniprot id: A0A1L8V2Q7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

53346:EM4838 RS12720
gene id: 53346:EM4838_RS12720
uniprot id: A0A2K8TIA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

53346:EM4838 RS05485
gene id: 53346:EM4838_RS05485
uniprot id: A0A1L8UUC3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

53346:EM4838 RS12075
gene id: 53346:EM4838_RS12075
uniprot id: A0A2K8THN1
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

53346:EM4838 RS07990
gene id: 53346:EM4838_RS07990
uniprot id: A0A1A6G5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

53346:EM4838 RS03445
gene id: 53346:EM4838_RS03445
uniprot id: A0A1L8V399
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS00705
gene id: 53346:EM4838_RS00705
uniprot id: A0A2K8TBS6
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

53346:EM4838 RS08035
gene id: 53346:EM4838_RS08035
uniprot id: A0A1A6GAC4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

53346:EM4838 RS07760
gene id: 53346:EM4838_RS07760
uniprot id: A0A2K8TFE6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

53346:EM4838 RS03405
gene id: 53346:EM4838_RS03405
uniprot id: A0A1A6GA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

53346:EM4838 RS03755
gene id: 53346:EM4838_RS03755
uniprot id: A0A2K8TF97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

53346:EM4838 RS07255
gene id: 53346:EM4838_RS07255
uniprot id: A0A2K8TF77
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

53346:EM4838 RS06750
gene id: 53346:EM4838_RS06750
uniprot id: A0A2K8TEZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14225
gene id: 53346:EM4838_RS14225
uniprot id: A0A1A6GBZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

53346:EM4838 RS10180
gene id: 53346:EM4838_RS10180
uniprot id: A0A2K8TGP0
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

53346:EM4838 RS15900
gene id: 53346:EM4838_RS15900
uniprot id: A0A2K8TJX7
names: Similarity
messages: Belongs to the peptidase S1B family.

53346:EM4838 RS11800
gene id: 53346:EM4838_RS11800
uniprot id: A0A2K8THI3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

53346:EM4838 RS04460
gene id: 53346:EM4838_RS04460
uniprot id: A0A1A6G6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS07055
gene id: 53346:EM4838_RS07055
uniprot id: A0A2K8TEZ0
names: Subcellular Location Annotation
messages: cytosol

53346:EM4838 RS14675
gene id: 53346:EM4838_RS14675
uniprot id: A0A1A6G850
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

53346:EM4838 RS14600
gene id: 53346:EM4838_RS14600
uniprot id: A0A1A6G5W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

53346:EM4838 RS06210
gene id: 53346:EM4838_RS06210
uniprot id: A0A2K8TEV7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07720
gene id: 53346:EM4838_RS07720
uniprot id: A0A2K8TJM5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

53346:EM4838 RS05225
gene id: 53346:EM4838_RS05225
uniprot id: A0A242KYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

53346:EM4838 RS01030
gene id: 53346:EM4838_RS01030
uniprot id: A0A2M9FRU5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12570
gene id: 53346:EM4838_RS12570
uniprot id: A0A1A6G6Q7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

53346:EM4838 RS13660
gene id: 53346:EM4838_RS13660
uniprot id: A0A2K8TIG0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

53346:EM4838 RS05175
gene id: 53346:EM4838_RS05175
uniprot id: A0A2K8TE63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

53346:EM4838 RS05080
gene id: 53346:EM4838_RS05080
uniprot id: A0A1L8V1U0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08785
gene id: 53346:EM4838_RS08785
uniprot id: A0A1I4NUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

53346:EM4838 RS05970
gene id: 53346:EM4838_RS05970
uniprot id: A0A1A6GBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

53346:EM4838 RS15190
gene id: 53346:EM4838_RS15190
uniprot id: A0A2T5DE45
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS12800
gene id: 53346:EM4838_RS12800
uniprot id: A0A1A6GBQ2
names: Similarity
messages: Belongs to the UPF0342 family.

53346:EM4838 RS05995
gene id: 53346:EM4838_RS05995
uniprot id: A0A2K8TER5
names: Similarity
messages: Belongs to the RecJ family.

53346:EM4838 RS15605
gene id: 53346:EM4838_RS15605
uniprot id: A0A1L8V2X6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

53346:EM4838 RS14270
gene id: 53346:EM4838_RS14270
uniprot id: A0A1A6GC69
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

53346:EM4838 RS04735
gene id: 53346:EM4838_RS04735
uniprot id: A0A2K8TDT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

53346:EM4838 RS04040
gene id: 53346:EM4838_RS04040
uniprot id: A0A2M9FP62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

53346:EM4838 RS05745
gene id: 53346:EM4838_RS05745
uniprot id: A0A2K8TEA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS15505
gene id: 53346:EM4838_RS15505
uniprot id: A0A1L8V2W0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

53346:EM4838 RS05680
gene id: 53346:EM4838_RS05680
uniprot id: A0A1A6G9H1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS10035
gene id: 53346:EM4838_RS10035
uniprot id: A0A2K8TGL2
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

53346:EM4838 RS14570
gene id: 53346:EM4838_RS14570
uniprot id: A0A1L8UN33
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

53346:EM4838 RS05205
gene id: 53346:EM4838_RS05205
uniprot id: A0A1A6G8D3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

53346:EM4838 RS14750
gene id: 53346:EM4838_RS14750
uniprot id: A0A1A6G835
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

53346:EM4838 RS14785
gene id: 53346:EM4838_RS14785
uniprot id: A0A1A6G6Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

53346:EM4838 RS00330
gene id: 53346:EM4838_RS00330
uniprot id: A0A1L8V3P7
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

53346:EM4838 RS01185
gene id: 53346:EM4838_RS01185
uniprot id: A0A2K8TDW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

53346:EM4838 RS04895
gene id: 53346:EM4838_RS04895
uniprot id: A0A1L8V1X5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

53346:EM4838 RS08870
gene id: 53346:EM4838_RS08870
uniprot id: A0A2K8TJM8
names: Similarity
messages: Belongs to the TPP enzyme family.

53346:EM4838 RS09595
gene id: 53346:EM4838_RS09595
uniprot id: A0A2K8TGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

53346:EM4838 RS15565
gene id: 53346:EM4838_RS15565
uniprot id: A0A1L8V3G6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

53346:EM4838 RS06360
gene id: 53346:EM4838_RS06360
uniprot id: A0A1I4IYD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

53346:EM4838 RS06820
gene id: 53346:EM4838_RS06820
uniprot id: A0A2K8TEW1
names: Similarity
messages: Belongs to the peptidase C59 family.

53346:EM4838 RS07280
gene id: 53346:EM4838_RS07280
uniprot id: A0A1L8UNR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

53346:EM4838 RS02050
gene id: 53346:EM4838_RS02050
uniprot id: A0A1A6G807
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

53346:EM4838 RS08920
gene id: 53346:EM4838_RS08920
uniprot id: A0A2K8TG52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06325
gene id: 53346:EM4838_RS06325
uniprot id: A0A1A6GAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

53346:EM4838 RS14660
gene id: 53346:EM4838_RS14660
uniprot id: A0A1A6G6S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

53346:EM4838 RS13225
gene id: 53346:EM4838_RS13225
uniprot id: A0A2K8TIH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

53346:EM4838 RS14255
gene id: 53346:EM4838_RS14255
uniprot id: A0A1I4P9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

53346:EM4838 RS11460
gene id: 53346:EM4838_RS11460
uniprot id: A0A2K8THB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

53346:EM4838 RS03365
gene id: 53346:EM4838_RS03365
uniprot id: A0A242KXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

53346:EM4838 RS05375
gene id: 53346:EM4838_RS05375
uniprot id: A0A1L8UU68
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

53346:EM4838 RS06415
gene id: 53346:EM4838_RS06415
uniprot id: A0A2K8TEM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14645
gene id: 53346:EM4838_RS14645
uniprot id: A0A1A6G854
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

53346:EM4838 RS07115
gene id: 53346:EM4838_RS07115
uniprot id: A0A2K8TF63
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

53346:EM4838 RS12995
gene id: 53346:EM4838_RS12995
uniprot id: A0A2K8TJY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

53346:EM4838 RS04945
gene id: 53346:EM4838_RS04945
uniprot id: A0A1A6G764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

53346:EM4838 RS13735
gene id: 53346:EM4838_RS13735
uniprot id: A0A2K8TIS6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

53346:EM4838 RS12120
gene id: 53346:EM4838_RS12120
uniprot id: A0A1I4JXX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14810
gene id: 53346:EM4838_RS14810
uniprot id: A0A1I4MJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

53346:EM4838 RS08250
gene id: 53346:EM4838_RS08250
uniprot id: A0A1A6G7I4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

53346:EM4838 RS14375
gene id: 53346:EM4838_RS14375
uniprot id: A0A2K8TIS2
names: Similarity
messages: Belongs to the LOG family.

53346:EM4838 RS03715
gene id: 53346:EM4838_RS03715
uniprot id: A0A2K8TDA1
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07165
gene id: 53346:EM4838_RS07165
uniprot id: A0A2K8TF72
names: Similarity
messages: Belongs to the EutP/PduV family.

53346:EM4838 RS08775
gene id: 53346:EM4838_RS08775
uniprot id: A0A2K8TG09
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS11200
gene id: 53346:EM4838_RS11200
uniprot id: A0A1A6G6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS04845
gene id: 53346:EM4838_RS04845
uniprot id: A0A1A6G779
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

53346:EM4838 RS09925
gene id: 53346:EM4838_RS09925
uniprot id: A0A1A6GBI6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

53346:EM4838 RS13385
gene id: 53346:EM4838_RS13385
uniprot id: A0A1A6GAL1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

53346:EM4838 RS01295
gene id: 53346:EM4838_RS01295
uniprot id: A0A2K8TDY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS10900
gene id: 53346:EM4838_RS10900
uniprot id: A0A2M9FU04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

53346:EM4838 RS05605
gene id: 53346:EM4838_RS05605
uniprot id: A0A2K8TEJ4
names: Function
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

53346:EM4838 RS04920
gene id: 53346:EM4838_RS04920
uniprot id: A0A2K8TE16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

53346:EM4838 RS12585
gene id: 53346:EM4838_RS12585
uniprot id: A0A1A6G5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

53346:EM4838 RS12550
gene id: 53346:EM4838_RS12550
uniprot id: A0A1L8UND7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

53346:EM4838 RS04430
gene id: 53346:EM4838_RS04430
uniprot id: A0A1A6G621
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS05535
gene id: 53346:EM4838_RS05535
uniprot id: A0A1L8UUB5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS00255
gene id: 53346:EM4838_RS00255
uniprot id: A0A242KVX8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

53346:EM4838 RS09610
gene id: 53346:EM4838_RS09610
uniprot id: A0A1A6G868
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14260
gene id: 53346:EM4838_RS14260
uniprot id: A0A1L8UPH8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

53346:EM4838 RS16320
gene id: 53346:EM4838_RS16320
uniprot id: A0A2K8TKB3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

53346:EM4838 RS14765
gene id: 53346:EM4838_RS14765
uniprot id: A0A1L8UMX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

53346:EM4838 RS05885
gene id: 53346:EM4838_RS05885
uniprot id: A0A2K8TEP5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

53346:EM4838 RS07875
gene id: 53346:EM4838_RS07875
uniprot id: A0A1L8V2F2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

53346:EM4838 RS11100
gene id: 53346:EM4838_RS11100
uniprot id: A0A2K8TH50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

53346:EM4838 RS02690
gene id: 53346:EM4838_RS02690
uniprot id: A0A1A6G8B7
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS04775
gene id: 53346:EM4838_RS04775
uniprot id: A0A1L8V1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS15235
gene id: 53346:EM4838_RS15235
uniprot id: A0A1A6G7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02340
gene id: 53346:EM4838_RS02340
uniprot id: A0A1L8UZK7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

53346:EM4838 RS14695
gene id: 53346:EM4838_RS14695
uniprot id: A0A1A6G6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

53346:EM4838 RS04645
gene id: 53346:EM4838_RS04645
uniprot id: A0A2K8TDU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08325
gene id: 53346:EM4838_RS08325
uniprot id: A0A1I4NSB1
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS13860
gene id: 53346:EM4838_RS13860
uniprot id: A0A2K8TIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

53346:EM4838 RS11090
gene id: 53346:EM4838_RS11090
uniprot id: A0A2K8TJ12
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

53346:EM4838 RS09300
gene id: 53346:EM4838_RS09300
uniprot id: A0A2K8TJN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

53346:EM4838 RS01270
gene id: 53346:EM4838_RS01270
uniprot id: A0A2K8TC24
names: Similarity
messages: Belongs to the aldolase LacD family.

53346:EM4838 RS08930
gene id: 53346:EM4838_RS08930
uniprot id: A0A2K8TG15
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

53346:EM4838 RS01925
gene id: 53346:EM4838_RS01925
uniprot id: A0A2K8TCB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12315
gene id: 53346:EM4838_RS12315
uniprot id: A0A1L8V148
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS14870
gene id: 53346:EM4838_RS14870
uniprot id: A0A1A6G6P0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

53346:EM4838 RS01280
gene id: 53346:EM4838_RS01280
uniprot id: A0A2K8TC26
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13530
gene id: 53346:EM4838_RS13530
uniprot id: A0A1L8V0P3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

53346:EM4838 RS13540
gene id: 53346:EM4838_RS13540
uniprot id: A0A2K8TK62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

53346:EM4838 RS06175
gene id: 53346:EM4838_RS06175
uniprot id: A0A1L8UT86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

53346:EM4838 RS13450
gene id: 53346:EM4838_RS13450
uniprot id: A0A1L8V0I3
names: Similarity
messages: Belongs to the CinA family.

53346:EM4838 RS11010
gene id: 53346:EM4838_RS11010
uniprot id: A0A2K8TH35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00210
gene id: 53346:EM4838_RS00210
uniprot id: A0A1A6G6X0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

53346:EM4838 RS06780
gene id: 53346:EM4838_RS06780
uniprot id: A0A2K8TEU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

53346:EM4838 RS14905
gene id: 53346:EM4838_RS14905
uniprot id: A0A1A6G6N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

53346:EM4838 RS02905
gene id: 53346:EM4838_RS02905
uniprot id: A0A1L8UV85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS02695
gene id: 53346:EM4838_RS02695
uniprot id: A0A1A6GAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

53346:EM4838 RS03940
gene id: 53346:EM4838_RS03940
uniprot id: A0A1L8V3W7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

53346:EM4838 RS07700
gene id: 53346:EM4838_RS07700
uniprot id: A0A2K8TFD6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

53346:EM4838 RS02955
gene id: 53346:EM4838_RS02955
uniprot id: A0A1L8UV76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS09175
gene id: 53346:EM4838_RS09175
uniprot id: A0A2K8TG79
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14300
gene id: 53346:EM4838_RS14300
uniprot id: A0A1I4P9N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

53346:EM4838 RS14340
gene id: 53346:EM4838_RS14340
uniprot id: A0A1I4P8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

53346:EM4838 RS02370
gene id: 53346:EM4838_RS02370
uniprot id: A0A1L8UZC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

53346:EM4838 RS00990
gene id: 53346:EM4838_RS00990
uniprot id: A0A2K8TBX6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03325
gene id: 53346:EM4838_RS03325
uniprot id: A0A1L8V3F7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09325
gene id: 53346:EM4838_RS09325
uniprot id: A0A2K8TG85
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09655
gene id: 53346:EM4838_RS09655
uniprot id: A0A242L161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

53346:EM4838 RS02870
gene id: 53346:EM4838_RS02870
uniprot id: A0A1L8UV77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

53346:EM4838 RS12595
gene id: 53346:EM4838_RS12595
uniprot id: A0A2K8TI48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

53346:EM4838 RS04395
gene id: 53346:EM4838_RS04395
uniprot id: A0A1A6G7L6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS07995
gene id: 53346:EM4838_RS07995
uniprot id: A0A2K8TFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

53346:EM4838 RS06970
gene id: 53346:EM4838_RS06970
uniprot id: A0A1L8URF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

53346:EM4838 RS15425
gene id: 53346:EM4838_RS15425
uniprot id: A0A242KVR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS06335
gene id: 53346:EM4838_RS06335
uniprot id: A0A2K8TGJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

53346:EM4838 RS09780
gene id: 53346:EM4838_RS09780
uniprot id: A0A1A6GBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

53346:EM4838 RS04425
gene id: 53346:EM4838_RS04425
uniprot id: A0A1I4LVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS10310
gene id: 53346:EM4838_RS10310
uniprot id: A0A2K8TH33
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS08300
gene id: 53346:EM4838_RS08300
uniprot id: A0A2K8TG03
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13330
gene id: 53346:EM4838_RS13330
uniprot id: A0A1I4QA11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

53346:EM4838 RS03945
gene id: 53346:EM4838_RS03945
uniprot id: A0A2K8TJJ3
names: Similarity
messages: Belongs to the fabD family.

53346:EM4838 RS08115
gene id: 53346:EM4838_RS08115
uniprot id: A0A2K8THH4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

53346:EM4838 RS14815
gene id: 53346:EM4838_RS14815
uniprot id: A0A1I4MK32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

53346:EM4838 RS03845
gene id: 53346:EM4838_RS03845
uniprot id: A0A1L8V4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

53346:EM4838 RS12165
gene id: 53346:EM4838_RS12165
uniprot id: A0A1A6G893
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

53346:EM4838 RS14920
gene id: 53346:EM4838_RS14920
uniprot id: A0A2K8TJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

53346:EM4838 RS14320
gene id: 53346:EM4838_RS14320
uniprot id: A0A2K8TJ15
names: Similarity
messages: Belongs to the TPP enzyme family.

53346:EM4838 RS10040
gene id: 53346:EM4838_RS10040
uniprot id: A0A2K8TGS1
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

53346:EM4838 RS09190
gene id: 53346:EM4838_RS09190
uniprot id: A0A2K8TG99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

53346:EM4838 RS07370
gene id: 53346:EM4838_RS07370
uniprot id: A0A2K8TFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

53346:EM4838 RS11955
gene id: 53346:EM4838_RS11955
uniprot id: A0A2K8THL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

53346:EM4838 RS13220
gene id: 53346:EM4838_RS13220
uniprot id: A0A1A6G9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

53346:EM4838 RS02765
gene id: 53346:EM4838_RS02765
uniprot id: A0A1A6G8E3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

53346:EM4838 RS12285
gene id: 53346:EM4838_RS12285
uniprot id: A0A1L8V179
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

53346:EM4838 RS02920
gene id: 53346:EM4838_RS02920
uniprot id: A0A1L8UVH7
names: Similarity
messages: Belongs to the DltD family.

53346:EM4838 RS10030
gene id: 53346:EM4838_RS10030
uniprot id: A0A2K8TGP2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

53346:EM4838 RS02880
gene id: 53346:EM4838_RS02880
uniprot id: A0A1L8UV29
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

53346:EM4838 RS08795
gene id: 53346:EM4838_RS08795
uniprot id: A0A1A6G9S9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01090
gene id: 53346:EM4838_RS01090
uniprot id: A0A1A6G7B6
names: Similarity
messages: Belongs to the ArsC family.

53346:EM4838 RS03685
gene id: 53346:EM4838_RS03685
uniprot id: A0A2K8TJV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

53346:EM4838 RS05950
gene id: 53346:EM4838_RS05950
uniprot id: A0A1L8UMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

53346:EM4838 RS11015
gene id: 53346:EM4838_RS11015
uniprot id: A0A2K8TH97
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

53346:EM4838 RS03745
gene id: 53346:EM4838_RS03745
uniprot id: A0A1A6G7D3
names: Subcellular Location Annotation
messages: Cell membrane

53346:EM4838 RS10220
gene id: 53346:EM4838_RS10220
uniprot id: A0A1A6G630
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

53346:EM4838 RS00915
gene id: 53346:EM4838_RS00915
uniprot id: A0A1V2UEA4
names: Similarity
messages: Belongs to the PemK/MazF family.

53346:EM4838 RS08025
gene id: 53346:EM4838_RS08025
uniprot id: A0A1A6G9A4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS04805
gene id: 53346:EM4838_RS04805
uniprot id: A0A2K8TDZ7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12015
gene id: 53346:EM4838_RS12015
uniprot id: A0A1I4K094
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

53346:EM4838 RS07375
gene id: 53346:EM4838_RS07375
uniprot id: A0A1L8UNP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS07845
gene id: 53346:EM4838_RS07845
uniprot id: A0A242L0A5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS07070
gene id: 53346:EM4838_RS07070
uniprot id: A0A2K8TFB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

53346:EM4838 RS07925
gene id: 53346:EM4838_RS07925
uniprot id: A0A2K8TFH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

53346:EM4838 RS10160
gene id: 53346:EM4838_RS10160
uniprot id: A0A2K8TGP5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05115
gene id: 53346:EM4838_RS05115
uniprot id: A0A2K8TE37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS09950
gene id: 53346:EM4838_RS09950
uniprot id: A0A2K8TGJ7
names: Similarity
messages: Belongs to the sigma-54 factor family.

53346:EM4838 RS14140
gene id: 53346:EM4838_RS14140
uniprot id: A0A1A6GAF3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

53346:EM4838 RS13035
gene id: 53346:EM4838_RS13035
uniprot id: A0A1L8ULK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS05465
gene id: 53346:EM4838_RS05465
uniprot id: A0A1A6G5N9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

53346:EM4838 RS05540
gene id: 53346:EM4838_RS05540
uniprot id: A0A1A6G520
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

53346:EM4838 RS13900
gene id: 53346:EM4838_RS13900
uniprot id: A0A1L8UQ12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS04185
gene id: 53346:EM4838_RS04185
uniprot id: A0A1I4K9Y1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

53346:EM4838 RS02255
gene id: 53346:EM4838_RS02255
uniprot id: A0A1A6G842
names: Similarity
messages: Belongs to the ABC transporter superfamily.

53346:EM4838 RS09210
gene id: 53346:EM4838_RS09210
uniprot id: A0A1A6G8Y9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

53346:EM4838 RS15950
gene id: 53346:EM4838_RS15950
uniprot id: A0A2K8TJY0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

53346:EM4838 RS03950
gene id: 53346:EM4838_RS03950
uniprot id: A0A1L8V4D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

53346:EM4838 RS14700
gene id: 53346:EM4838_RS14700
uniprot id: A0A1A6G844
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

53346:EM4838 RS15265
gene id: 53346:EM4838_RS15265
uniprot id: A0A1A6G669
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

53346:EM4838 RS02490
gene id: 53346:EM4838_RS02490
uniprot id: A0A1V2UB38
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

53346:EM4838 RS10140
gene id: 53346:EM4838_RS10140
uniprot id: A0A1L8USU8
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05275
gene id: 53346:EM4838_RS05275
uniprot id: A0A1I4LPM5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS07385
gene id: 53346:EM4838_RS07385
uniprot id: A0A1L8UNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

53346:EM4838 RS15115
gene id: 53346:EM4838_RS15115
uniprot id: A0A2K8TJ70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS05515
gene id: 53346:EM4838_RS05515
uniprot id: A0A2K8TE54
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Belongs to the GARS family.

53346:EM4838 RS08730
gene id: 53346:EM4838_RS08730
uniprot id: A0A2K8TFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02985
gene id: 53346:EM4838_RS02985
uniprot id: A0A2K8TD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

53346:EM4838 RS01420
gene id: 53346:EM4838_RS01420
uniprot id: A0A2M9FNH7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

53346:EM4838 RS12130
gene id: 53346:EM4838_RS12130
uniprot id: A0A2K8THP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01790
gene id: 53346:EM4838_RS01790
uniprot id: A0A2K8TCB7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

53346:EM4838 RS12200
gene id: 53346:EM4838_RS12200
uniprot id: A0A1A6G6X2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

53346:EM4838 RS14295
gene id: 53346:EM4838_RS14295
uniprot id: A0A1A6GBY2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

53346:EM4838 RS11475
gene id: 53346:EM4838_RS11475
uniprot id: A0A1L8UWA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01655
gene id: 53346:EM4838_RS01655
uniprot id: A0A2K8TC96
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

53346:EM4838 RS13335
gene id: 53346:EM4838_RS13335
uniprot id: A0A1L8V0L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

53346:EM4838 RS06730
gene id: 53346:EM4838_RS06730
uniprot id: A0A1L8UUW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS07955
gene id: 53346:EM4838_RS07955
uniprot id: A0A2K8TFI5
names: Similarity
messages: Belongs to the ribF family.

53346:EM4838 RS07650
gene id: 53346:EM4838_RS07650
uniprot id: A0A1A6G728
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

53346:EM4838 RS03625
gene id: 53346:EM4838_RS03625
uniprot id: A0A1L8V3S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

53346:EM4838 RS11395
gene id: 53346:EM4838_RS11395
uniprot id: A0A1I4K6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS15380
gene id: 53346:EM4838_RS15380
uniprot id: A0A1L8V2I5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS10645
gene id: 53346:EM4838_RS10645
uniprot id: A0A242L1U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

53346:EM4838 RS02205
gene id: 53346:EM4838_RS02205
uniprot id: A0A2K8TCJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

53346:EM4838 RS11625
gene id: 53346:EM4838_RS11625
uniprot id: A0A2K8THG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.
messages: Belongs to the peptidase C40 family.

53346:EM4838 RS01965
gene id: 53346:EM4838_RS01965
uniprot id: A0A1A6GA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

53346:EM4838 RS01195
gene id: 53346:EM4838_RS01195
uniprot id: A0A1A6G7M3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS00640
gene id: 53346:EM4838_RS00640
uniprot id: A0A2K8TBN6
names: Similarity
messages: Belongs to the YoeB family.

53346:EM4838 RS11285
gene id: 53346:EM4838_RS11285
uniprot id: A0A2K8TJ42
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

53346:EM4838 RS10910
gene id: 53346:EM4838_RS10910
uniprot id: A0A2K8TJW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02840
gene id: 53346:EM4838_RS02840
uniprot id: A0A1A6G9E1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

53346:EM4838 RS09970
gene id: 53346:EM4838_RS09970
uniprot id: A0A1L8UXS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

53346:EM4838 RS00315
gene id: 53346:EM4838_RS00315
uniprot id: A0A1L8V335
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS11140
gene id: 53346:EM4838_RS11140
uniprot id: A0A2K8THH7
names: Similarity
messages: Belongs to the EutP/PduV family.

53346:EM4838 RS15905
gene id: 53346:EM4838_RS15905
uniprot id: A0A2K8TK46
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS03875
gene id: 53346:EM4838_RS03875
uniprot id: A0A1L8V3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

53346:EM4838 RS14775
gene id: 53346:EM4838_RS14775
uniprot id: A0A1A6G829
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

53346:EM4838 RS10195
gene id: 53346:EM4838_RS10195
uniprot id: A0A2K8TGV0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS13200
gene id: 53346:EM4838_RS13200
uniprot id: A0A1L8V0R0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS11535
gene id: 53346:EM4838_RS11535
uniprot id: A0A1L8UWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS06230
gene id: 53346:EM4838_RS06230
uniprot id: A0A2K8TEJ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

53346:EM4838 RS01180
gene id: 53346:EM4838_RS01180
uniprot id: A0A2K8TBZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

53346:EM4838 RS07590
gene id: 53346:EM4838_RS07590
uniprot id: A0A2K8TFA4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS06030
gene id: 53346:EM4838_RS06030
uniprot id: A0A1I4QHS4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

53346:EM4838 RS06015
gene id: 53346:EM4838_RS06015
uniprot id: A0A1L8UMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

53346:EM4838 RS10610
gene id: 53346:EM4838_RS10610
uniprot id: A0A1I4N259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

53346:EM4838 RS00835
gene id: 53346:EM4838_RS00835
uniprot id: A0A1A6G603
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS00710
gene id: 53346:EM4838_RS00710
uniprot id: A0A1L8V0E4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

53346:EM4838 RS12110
gene id: 53346:EM4838_RS12110
uniprot id: A0A1A6GB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

53346:EM4838 RS05805
gene id: 53346:EM4838_RS05805
uniprot id: A0A1L8UMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

53346:EM4838 RS07325
gene id: 53346:EM4838_RS07325
uniprot id: A0A2K8TFG6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

53346:EM4838 RS05270
gene id: 53346:EM4838_RS05270
uniprot id: A0A1A6G6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01170
gene id: 53346:EM4838_RS01170
uniprot id: A0A1A6G7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

53346:EM4838 RS09225
gene id: 53346:EM4838_RS09225
uniprot id: A0A1A6GAL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

53346:EM4838 RS13245
gene id: 53346:EM4838_RS13245
uniprot id: A0A2K8TI66
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13025
gene id: 53346:EM4838_RS13025
uniprot id: A0A1A6G6I0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

53346:EM4838 RS09455
gene id: 53346:EM4838_RS09455
uniprot id: A0A1A6G767
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

53346:EM4838 RS12635
gene id: 53346:EM4838_RS12635
uniprot id: A0A1A6G6F1
names: Function
messages: Required for transformation and DNA binding.

53346:EM4838 RS15160
gene id: 53346:EM4838_RS15160
uniprot id: A0A1A6G686
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

53346:EM4838 RS02640
gene id: 53346:EM4838_RS02640
uniprot id: A0A1L8UV91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

53346:EM4838 RS06795
gene id: 53346:EM4838_RS06795
uniprot id: A0A1A6GCG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS08020
gene id: 53346:EM4838_RS08020
uniprot id: A0A1A6GBX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

53346:EM4838 RS02155
gene id: 53346:EM4838_RS02155
uniprot id: A0A2K8TCL9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02835
gene id: 53346:EM4838_RS02835
uniprot id: A0A1A6G9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

53346:EM4838 RS09720
gene id: 53346:EM4838_RS09720
uniprot id: A0A2K8TIC2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

53346:EM4838 RS15125
gene id: 53346:EM4838_RS15125
uniprot id: A0A2K8TJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08210
gene id: 53346:EM4838_RS08210
uniprot id: A0A2K8TFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

53346:EM4838 RS10975
gene id: 53346:EM4838_RS10975
uniprot id: A0A1L8UTM4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS01055
gene id: 53346:EM4838_RS01055
uniprot id: A0A2K8TC84
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

53346:EM4838 RS07260
gene id: 53346:EM4838_RS07260
uniprot id: A0A1L8UNX8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

53346:EM4838 RS13545
gene id: 53346:EM4838_RS13545
uniprot id: A0A1L8V093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

53346:EM4838 RS04790
gene id: 53346:EM4838_RS04790
uniprot id: A0A1L8V1K3
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

53346:EM4838 RS11040
gene id: 53346:EM4838_RS11040
uniprot id: A0A1I4M900
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

53346:EM4838 RS00050
gene id: 53346:EM4838_RS00050
uniprot id: A0A1I4L3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14330
gene id: 53346:EM4838_RS14330
uniprot id: A0A1L8UP56
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07185
gene id: 53346:EM4838_RS07185
uniprot id: A0A2K8TH03
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

53346:EM4838 RS03355
gene id: 53346:EM4838_RS03355
uniprot id: A0A1A6G6A3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

53346:EM4838 RS07075
gene id: 53346:EM4838_RS07075
uniprot id: A0A2K8TF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

53346:EM4838 RS06760
gene id: 53346:EM4838_RS06760
uniprot id: A0A2K8TEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

53346:EM4838 RS10710
gene id: 53346:EM4838_RS10710
uniprot id: A0A1L8UMK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

53346:EM4838 RS12290
gene id: 53346:EM4838_RS12290
uniprot id: A0A1L8V0X6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

53346:EM4838 RS07965
gene id: 53346:EM4838_RS07965
uniprot id: A0A1A6G427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

53346:EM4838 RS02830
gene id: 53346:EM4838_RS02830
uniprot id: A0A1L8UV35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

53346:EM4838 RS07870
gene id: 53346:EM4838_RS07870
uniprot id: A0A1A6G401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

53346:EM4838 RS14855
gene id: 53346:EM4838_RS14855
uniprot id: A0A1L8UN35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

53346:EM4838 RS13665
gene id: 53346:EM4838_RS13665
uniprot id: A0A1I4PVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS03765
gene id: 53346:EM4838_RS03765
uniprot id: A0A1L8V448
names: Similarity
messages: Belongs to the HesB/IscA family.

53346:EM4838 RS10730
gene id: 53346:EM4838_RS10730
uniprot id: A0A1A6G6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

53346:EM4838 RS09650
gene id: 53346:EM4838_RS09650
uniprot id: A0A1A6G765
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

53346:EM4838 RS04855
gene id: 53346:EM4838_RS04855
uniprot id: A0A1L8V1G4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

53346:EM4838 RS11935
gene id: 53346:EM4838_RS11935
uniprot id: A0A1L8V110
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS02750
gene id: 53346:EM4838_RS02750
uniprot id: A0A1A6G9D2
names: Similarity
messages: Belongs to the glutamine synthetase family.

53346:EM4838 RS05660
gene id: 53346:EM4838_RS05660
uniprot id: A0A2K8TJT2
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12655
gene id: 53346:EM4838_RS12655
uniprot id: A0A1I4PK88
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

53346:EM4838 RS02770
gene id: 53346:EM4838_RS02770
uniprot id: A0A242KX96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS15625
gene id: 53346:EM4838_RS15625
uniprot id: A0A1L8V2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

53346:EM4838 RS15250
gene id: 53346:EM4838_RS15250
uniprot id: A0A1I4L051
names: Similarity
messages: Belongs to the UPF0178 family.

53346:EM4838 RS14760
gene id: 53346:EM4838_RS14760
uniprot id: A0A1A6G6R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

53346:EM4838 RS01550
gene id: 53346:EM4838_RS01550
uniprot id: A0A2K8TCB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12170
gene id: 53346:EM4838_RS12170
uniprot id: A0A1L8V118
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

53346:EM4838 RS07655
gene id: 53346:EM4838_RS07655
uniprot id: A0A1L8V2S1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

53346:EM4838 RS02655
gene id: 53346:EM4838_RS02655
uniprot id: A0A1L8UVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

53346:EM4838 RS05240
gene id: 53346:EM4838_RS05240
uniprot id: A0A1L8V1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

53346:EM4838 RS13380
gene id: 53346:EM4838_RS13380
uniprot id: A0A2K8TI93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS10825
gene id: 53346:EM4838_RS10825
uniprot id: A0A2K8TH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

53346:EM4838 RS14635
gene id: 53346:EM4838_RS14635
uniprot id: A0A1A6G9K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

53346:EM4838 RS11470
gene id: 53346:EM4838_RS11470
uniprot id: A0A2K8THE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06670
gene id: 53346:EM4838_RS06670
uniprot id: A0A1I4J2P5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14055
gene id: 53346:EM4838_RS14055
uniprot id: A0A1A6G776
names: Similarity
messages: Belongs to the CtsR family.

53346:EM4838 RS10830
gene id: 53346:EM4838_RS10830
uniprot id: A0A1L8UTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS15955
gene id: 53346:EM4838_RS15955
uniprot id: A0A2K8TJY4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

53346:EM4838 RS09810
gene id: 53346:EM4838_RS09810
uniprot id: A0A1A6GAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

53346:EM4838 RS06975
gene id: 53346:EM4838_RS06975
uniprot id: A0A1L8URD1
names: Similarity
messages: Belongs to the asp23 family.

53346:EM4838 RS09355
gene id: 53346:EM4838_RS09355
uniprot id: A0A1L8UQY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS02245
gene id: 53346:EM4838_RS02245
uniprot id: A0A1A6G945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS13620
gene id: 53346:EM4838_RS13620
uniprot id: A0A2K8TID4
names: Similarity
messages: Belongs to the EssB family.

53346:EM4838 RS07795
gene id: 53346:EM4838_RS07795
uniprot id: A0A1A6G4Q6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

53346:EM4838 RS10090
gene id: 53346:EM4838_RS10090
uniprot id: A0A1A6GA54
names: Similarity
messages: Belongs to the thioredoxin family.

53346:EM4838 RS03780
gene id: 53346:EM4838_RS03780
uniprot id: A0A2K8TDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

53346:EM4838 RS03710
gene id: 53346:EM4838_RS03710
uniprot id: A0A2K8TD92
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

53346:EM4838 RS07105
gene id: 53346:EM4838_RS07105
uniprot id: A0A2K8TF02
names: Similarity
messages: Belongs to the heat shock protein 70 family.

53346:EM4838 RS06665
gene id: 53346:EM4838_RS06665
uniprot id: A0A2K8TGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

53346:EM4838 RS03540
gene id: 53346:EM4838_RS03540
uniprot id: A0A1L8V482
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS14560
gene id: 53346:EM4838_RS14560
uniprot id: A0A1L8UN32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

53346:EM4838 RS07840
gene id: 53346:EM4838_RS07840
uniprot id: A0A1A6G567
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

53346:EM4838 RS15280
gene id: 53346:EM4838_RS15280
uniprot id: A0A1A6G7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

53346:EM4838 RS11390
gene id: 53346:EM4838_RS11390
uniprot id: A0A1A6G519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

53346:EM4838 RS05090
gene id: 53346:EM4838_RS05090
uniprot id: A0A1L8V1T5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

53346:EM4838 RS14210
gene id: 53346:EM4838_RS14210
uniprot id: A0A1A6GDH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14280
gene id: 53346:EM4838_RS14280
uniprot id: A0A1A6GAV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

53346:EM4838 RS05210
gene id: 53346:EM4838_RS05210
uniprot id: A0A1A6G5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

53346:EM4838 RS00105
gene id: 53346:EM4838_RS00105
uniprot id: A0A1L8V3G9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

53346:EM4838 RS14485
gene id: 53346:EM4838_RS14485
uniprot id: A0A2K8TIU5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

53346:EM4838 RS11105
gene id: 53346:EM4838_RS11105
uniprot id: A0A2K8TH62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

53346:EM4838 RS15325
gene id: 53346:EM4838_RS15325
uniprot id: A0A1A6G565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS07420
gene id: 53346:EM4838_RS07420
uniprot id: A0A1L8UNT6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

53346:EM4838 RS13655
gene id: 53346:EM4838_RS13655
uniprot id: A0A2K8TIE4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

53346:EM4838 RS09930
gene id: 53346:EM4838_RS09930
uniprot id: A0A1I4N7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

53346:EM4838 RS14355
gene id: 53346:EM4838_RS14355
uniprot id: A0A1L8UPF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS04830
gene id: 53346:EM4838_RS04830
uniprot id: A0A1L8V1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

53346:EM4838 RS03360
gene id: 53346:EM4838_RS03360
uniprot id: A0A1I4MX89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14575
gene id: 53346:EM4838_RS14575
uniprot id: A0A1I4MGQ5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

53346:EM4838 RS03595
gene id: 53346:EM4838_RS03595
uniprot id: A0A1A6G986
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS00740
gene id: 53346:EM4838_RS00740
uniprot id: A0A2K8TBR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS07360
gene id: 53346:EM4838_RS07360
uniprot id: A0A1I4JGK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

53346:EM4838 RS02540
gene id: 53346:EM4838_RS02540
uniprot id: A0A2K8TCU5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14800
gene id: 53346:EM4838_RS14800
uniprot id: A0A1A6G825
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

53346:EM4838 RS11745
gene id: 53346:EM4838_RS11745
uniprot id: A0A1L8UMD4
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

53346:EM4838 RS11855
gene id: 53346:EM4838_RS11855
uniprot id: A0A1A6GAD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

53346:EM4838 RS00030
gene id: 53346:EM4838_RS00030
uniprot id: A0A1L8V3G6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

53346:EM4838 RS01470
gene id: 53346:EM4838_RS01470
uniprot id: A0A1A6G8H7
names: Similarity
messages: Belongs to the peptidase C56 family.

53346:EM4838 RS02720
gene id: 53346:EM4838_RS02720
uniprot id: A0A1A6GB01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

53346:EM4838 RS10025
gene id: 53346:EM4838_RS10025
uniprot id: A0A1I4N716
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

53346:EM4838 RS12105
gene id: 53346:EM4838_RS12105
uniprot id: A0A2K8THV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

53346:EM4838 RS13040
gene id: 53346:EM4838_RS13040
uniprot id: A0A1L8ULA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

53346:EM4838 RS11920
gene id: 53346:EM4838_RS11920
uniprot id: A0A2K8THS5
names: Function
names: Subunit
messages: Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
messages: Homooctamer.

53346:EM4838 RS01520
gene id: 53346:EM4838_RS01520
uniprot id: A0A2K8TC55
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

53346:EM4838 RS10810
gene id: 53346:EM4838_RS10810
uniprot id: A0A2K8TIW6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12395
gene id: 53346:EM4838_RS12395
uniprot id: A0A1I4PMW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

53346:EM4838 RS01820
gene id: 53346:EM4838_RS01820
uniprot id: A0A2K8TC97
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

53346:EM4838 RS06895
gene id: 53346:EM4838_RS06895
uniprot id: A0A2K8TF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06055
gene id: 53346:EM4838_RS06055
uniprot id: A0A2K8TGF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

53346:EM4838 RS00810
gene id: 53346:EM4838_RS00810
uniprot id: A0A1V2UEA1
names: Similarity
messages: Belongs to the UPF0145 family.

53346:EM4838 RS06525
gene id: 53346:EM4838_RS06525
uniprot id: A0A2K8TEP3
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

53346:EM4838 RS05570
gene id: 53346:EM4838_RS05570
uniprot id: A0A2K8TE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

53346:EM4838 RS12215
gene id: 53346:EM4838_RS12215
uniprot id: A0A1A6G883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00630
gene id: 53346:EM4838_RS00630
uniprot id: A0A2K8TBQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

53346:EM4838 RS06855
gene id: 53346:EM4838_RS06855
uniprot id: A0A2K8TF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14175
gene id: 53346:EM4838_RS14175
uniprot id: A0A242KVA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

53346:EM4838 RS07640
gene id: 53346:EM4838_RS07640
uniprot id: A0A1I4JJP4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

53346:EM4838 RS03330
gene id: 53346:EM4838_RS03330
uniprot id: A0A1A6G6A7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03650
gene id: 53346:EM4838_RS03650
uniprot id: A0A1A6G6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00075
gene id: 53346:EM4838_RS00075
uniprot id: A0A1L8V333
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03535
gene id: 53346:EM4838_RS03535
uniprot id: A0A1L8V3P2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

53346:EM4838 RS03870
gene id: 53346:EM4838_RS03870
uniprot id: A0A1L8V466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

53346:EM4838 RS03955
gene id: 53346:EM4838_RS03955
uniprot id: A0A1L8V3I8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

53346:EM4838 RS15995
gene id: 53346:EM4838_RS15995
uniprot id: A0A2K8TK08
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14795
gene id: 53346:EM4838_RS14795
uniprot id: A0A1A6G6S3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

53346:EM4838 RS12220
gene id: 53346:EM4838_RS12220
uniprot id: A0A1A6G5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS09440
gene id: 53346:EM4838_RS09440
uniprot id: A0A1A6G799
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

53346:EM4838 RS03350
gene id: 53346:EM4838_RS03350
uniprot id: A0A1A6G6J6
names: Similarity
messages: Belongs to the asp23 family.

53346:EM4838 RS09550
gene id: 53346:EM4838_RS09550
uniprot id: A0A1A6G784
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

53346:EM4838 RS02465
gene id: 53346:EM4838_RS02465
uniprot id: A0A1L8UZA8
names: Similarity
messages: Belongs to the YjdM family.

53346:EM4838 RS13965
gene id: 53346:EM4838_RS13965
uniprot id: A0A1L8UQ62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

53346:EM4838 RS14565
gene id: 53346:EM4838_RS14565
uniprot id: A0A1L8UN45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

53346:EM4838 RS14850
gene id: 53346:EM4838_RS14850
uniprot id: A0A2K8TJ17
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

53346:EM4838 RS01265
gene id: 53346:EM4838_RS01265
uniprot id: A0A2K8TC50
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

53346:EM4838 RS02020
gene id: 53346:EM4838_RS02020
uniprot id: A0A1L8UZN2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

53346:EM4838 RS10635
gene id: 53346:EM4838_RS10635
uniprot id: A0A2K8TGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

53346:EM4838 RS15175
gene id: 53346:EM4838_RS15175
uniprot id: A0A1A6G7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

53346:EM4838 RS08715
gene id: 53346:EM4838_RS08715
uniprot id: A0A1A6G8N9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

53346:EM4838 RS03320
gene id: 53346:EM4838_RS03320
uniprot id: A0A1I4MXA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

53346:EM4838 RS05670
gene id: 53346:EM4838_RS05670
uniprot id: A0A1A6G4W9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

53346:EM4838 RS04940
gene id: 53346:EM4838_RS04940
uniprot id: A0A2K8TDW3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

53346:EM4838 RS11750
gene id: 53346:EM4838_RS11750
uniprot id: A0A1L8UM11
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS05480
gene id: 53346:EM4838_RS05480
uniprot id: A0A2K8TE61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

53346:EM4838 RS01440
gene id: 53346:EM4838_RS01440
uniprot id: A0A2K8TC56
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

53346:EM4838 RS02295
gene id: 53346:EM4838_RS02295
uniprot id: A0A1L8UZK3
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS15085
gene id: 53346:EM4838_RS15085
uniprot id: A0A1I4MN88
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05865
gene id: 53346:EM4838_RS05865
uniprot id: A0A2K8TEH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity.

53346:EM4838 RS07860
gene id: 53346:EM4838_RS07860
uniprot id: A0A1A6G508
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

53346:EM4838 RS11700
gene id: 53346:EM4838_RS11700
uniprot id: A0A2K8THG4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

53346:EM4838 RS14735
gene id: 53346:EM4838_RS14735
uniprot id: A0A1A6G6R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

53346:EM4838 RS16795
gene id: 53346:EM4838_RS16795
uniprot id: A0A242L263
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS03705
gene id: 53346:EM4838_RS03705
uniprot id: A0A2K8TF88
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03470
gene id: 53346:EM4838_RS03470
uniprot id: A0A1A6GAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

53346:EM4838 RS12085
gene id: 53346:EM4838_RS12085
uniprot id: A0A1L8V184
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS11735
gene id: 53346:EM4838_RS11735
uniprot id: A0A1A6GA55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

53346:EM4838 RS04385
gene id: 53346:EM4838_RS04385
uniprot id: A0A1L8V442
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

53346:EM4838 RS09400
gene id: 53346:EM4838_RS09400
uniprot id: A0A2K8TGK2
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS02310
gene id: 53346:EM4838_RS02310
uniprot id: A0A2K8TCN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

53346:EM4838 RS15350
gene id: 53346:EM4838_RS15350
uniprot id: A0A2K8TJG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

53346:EM4838 RS08185
gene id: 53346:EM4838_RS08185
uniprot id: A0A2K8TFQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

53346:EM4838 RS13320
gene id: 53346:EM4838_RS13320
uniprot id: A0A1L8V0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

53346:EM4838 RS08535
gene id: 53346:EM4838_RS08535
uniprot id: A0A2K8TFU5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS06775
gene id: 53346:EM4838_RS06775
uniprot id: A0A2K8TEU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

53346:EM4838 RS04350
gene id: 53346:EM4838_RS04350
uniprot id: A0A2K8TDV5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

53346:EM4838 RS00555
gene id: 53346:EM4838_RS00555
uniprot id: A0A2K8TBM9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

53346:EM4838 RS15285
gene id: 53346:EM4838_RS15285
uniprot id: A0A1L8V2H2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

53346:EM4838 RS07730
gene id: 53346:EM4838_RS07730
uniprot id: A0A1L8V2F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

53346:EM4838 RS14590
gene id: 53346:EM4838_RS14590
uniprot id: A0A1A6G4W3
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03800
gene id: 53346:EM4838_RS03800
uniprot id: A0A1L8V3G1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

53346:EM4838 RS10740
gene id: 53346:EM4838_RS10740
uniprot id: A0A2K8TH47
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06630
gene id: 53346:EM4838_RS06630
uniprot id: A0A2K8TES8
names: Similarity
messages: Belongs to the UPF0340 family.

53346:EM4838 RS06740
gene id: 53346:EM4838_RS06740
uniprot id: A0A2K8TET0
names: Similarity
messages: Belongs to the CFA/CMAS family.

53346:EM4838 RS01330
gene id: 53346:EM4838_RS01330
uniprot id: A0A2K8TC34
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

53346:EM4838 RS04415
gene id: 53346:EM4838_RS04415
uniprot id: A0A1L8V4E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS13400
gene id: 53346:EM4838_RS13400
uniprot id: A0A2K8TIA9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

53346:EM4838 RS08305
gene id: 53346:EM4838_RS08305
uniprot id: A0A1L8UKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

53346:EM4838 RS12780
gene id: 53346:EM4838_RS12780
uniprot id: A0A1L8UQM1
names: Similarity
messages: Belongs to the UxaA family.

53346:EM4838 RS03430
gene id: 53346:EM4838_RS03430
uniprot id: A0A242KYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00410
gene id: 53346:EM4838_RS00410
uniprot id: A0A2K8TBQ5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06035
gene id: 53346:EM4838_RS06035
uniprot id: A0A1A6G7U5
names: Similarity
messages: Belongs to the Fur family.

53346:EM4838 RS10590
gene id: 53346:EM4838_RS10590
uniprot id: A0A1L8UMV0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

53346:EM4838 RS00275
gene id: 53346:EM4838_RS00275
uniprot id: A0A1I4L6W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS00735
gene id: 53346:EM4838_RS00735
uniprot id: A0A2K8TBS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

53346:EM4838 RS08905
gene id: 53346:EM4838_RS08905
uniprot id: A0A2K8TG30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

53346:EM4838 RS04930
gene id: 53346:EM4838_RS04930
uniprot id: A0A2K8TJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

53346:EM4838 RS00730
gene id: 53346:EM4838_RS00730
uniprot id: A0A2K8TDN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

53346:EM4838 RS07770
gene id: 53346:EM4838_RS07770
uniprot id: A0A1A6G5Q8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

53346:EM4838 RS09385
gene id: 53346:EM4838_RS09385
uniprot id: A0A2K8TG92
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

53346:EM4838 RS03850
gene id: 53346:EM4838_RS03850
uniprot id: A0A1I4LXW7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

53346:EM4838 RS10985
gene id: 53346:EM4838_RS10985
uniprot id: A0A2K8TIZ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS14840
gene id: 53346:EM4838_RS14840
uniprot id: A0A1A6G6P5
names: Similarity
messages: Belongs to the asp23 family.

53346:EM4838 RS01400
gene id: 53346:EM4838_RS01400
uniprot id: A0A2M9FNF2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

53346:EM4838 RS07505
gene id: 53346:EM4838_RS07505
uniprot id: A0A1I4JHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS07630
gene id: 53346:EM4838_RS07630
uniprot id: A0A2K8TH92
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

53346:EM4838 RS12405
gene id: 53346:EM4838_RS12405
uniprot id: A0A2K8TI11
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

53346:EM4838 RS12430
gene id: 53346:EM4838_RS12430
uniprot id: A0A2K8THV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

53346:EM4838 RS04910
gene id: 53346:EM4838_RS04910
uniprot id: A0A2K8TE01
names: Similarity
messages: Belongs to the CvfB family.

53346:EM4838 RS10935
gene id: 53346:EM4838_RS10935
uniprot id: A0A2K8TH23
names: Similarity
messages: Belongs to the DCK/DGK family.

53346:EM4838 RS15230
gene id: 53346:EM4838_RS15230
uniprot id: A0A1A6G7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

53346:EM4838 RS06320
gene id: 53346:EM4838_RS06320
uniprot id: A0A1A6GAN4
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

53346:EM4838 RS09430
gene id: 53346:EM4838_RS09430
uniprot id: A0A1L8UXZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

53346:EM4838 RS09510
gene id: 53346:EM4838_RS09510
uniprot id: A0A2K8TGC7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

53346:EM4838 RS14995
gene id: 53346:EM4838_RS14995
uniprot id: A0A2K8TJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

53346:EM4838 RS06770
gene id: 53346:EM4838_RS06770
uniprot id: A0A2K8TJY2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

53346:EM4838 RS12185
gene id: 53346:EM4838_RS12185
uniprot id: A0A1L8V1A6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

53346:EM4838 RS13525
gene id: 53346:EM4838_RS13525
uniprot id: A0A1L8V0C2
names: Similarity
messages: Belongs to the ycf81 family.

53346:EM4838 RS12370
gene id: 53346:EM4838_RS12370
uniprot id: A0A1L8V107
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS08865
gene id: 53346:EM4838_RS08865
uniprot id: A0A1L8UX09
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

53346:EM4838 RS03420
gene id: 53346:EM4838_RS03420
uniprot id: A0A1L8V3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

53346:EM4838 RS09200
gene id: 53346:EM4838_RS09200
uniprot id: A0A1A6GAL4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

53346:EM4838 RS13250
gene id: 53346:EM4838_RS13250
uniprot id: A0A2K8TI74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

53346:EM4838 RS14715
gene id: 53346:EM4838_RS14715
uniprot id: A0A1A6G9H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

53346:EM4838 RS13415
gene id: 53346:EM4838_RS13415
uniprot id: A0A1L8V0E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS13595
gene id: 53346:EM4838_RS13595
uniprot id: A0A242KVA5
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

53346:EM4838 RS05255
gene id: 53346:EM4838_RS05255
uniprot id: A0A1A6G8C3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

53346:EM4838 RS11570
gene id: 53346:EM4838_RS11570
uniprot id: A0A1A6G4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01120
gene id: 53346:EM4838_RS01120
uniprot id: A0A1A6G7N5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

53346:EM4838 RS15530
gene id: 53346:EM4838_RS15530
uniprot id: A0A2K8TJE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS04935
gene id: 53346:EM4838_RS04935
uniprot id: A0A1A6G8H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

53346:EM4838 RS02505
gene id: 53346:EM4838_RS02505
uniprot id: A0A2K8TCM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

53346:EM4838 RS09330
gene id: 53346:EM4838_RS09330
uniprot id: A0A242L1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

53346:EM4838 RS13875
gene id: 53346:EM4838_RS13875
uniprot id: A0A1A6G8C7
names: Similarity
messages: Belongs to the Dps family.

53346:EM4838 RS09275
gene id: 53346:EM4838_RS09275
uniprot id: A0A2K8TGA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

53346:EM4838 RS12810
gene id: 53346:EM4838_RS12810
uniprot id: A0A242KU74
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

53346:EM4838 RS09830
gene id: 53346:EM4838_RS09830
uniprot id: A0A1A6GBF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS00200
gene id: 53346:EM4838_RS00200
uniprot id: A0A2K8TBT9
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS08235
gene id: 53346:EM4838_RS08235
uniprot id: A0A1A6G8U5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

53346:EM4838 RS02040
gene id: 53346:EM4838_RS02040
uniprot id: A0A2K8TCJ9
names: Similarity
messages: Belongs to the peptidase M13 family.

53346:EM4838 RS15385
gene id: 53346:EM4838_RS15385
uniprot id: A0A1L8V310
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

53346:EM4838 RS13560
gene id: 53346:EM4838_RS13560
uniprot id: A0A1L8V0G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

53346:EM4838 RS02650
gene id: 53346:EM4838_RS02650
uniprot id: A0A1L8UVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

53346:EM4838 RS05870
gene id: 53346:EM4838_RS05870
uniprot id: A0A2K8TED1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

53346:EM4838 RS08885
gene id: 53346:EM4838_RS08885
uniprot id: A0A1L8UWW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

53346:EM4838 RS10250
gene id: 53346:EM4838_RS10250
uniprot id: A0A1L8USY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

53346:EM4838 RS10920
gene id: 53346:EM4838_RS10920
uniprot id: A0A2K8THC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS06470
gene id: 53346:EM4838_RS06470
uniprot id: A0A2K8TEN0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

53346:EM4838 RS08310
gene id: 53346:EM4838_RS08310
uniprot id: A0A2K8THL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

53346:EM4838 RS09425
gene id: 53346:EM4838_RS09425
uniprot id: A0A1L8UY40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

53346:EM4838 RS03510
gene id: 53346:EM4838_RS03510
uniprot id: A0A1L8V3Y3
names: Similarity
messages: Belongs to the SfsA family.

53346:EM4838 RS04800
gene id: 53346:EM4838_RS04800
uniprot id: A0A1I4PIA1
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06570
gene id: 53346:EM4838_RS06570
uniprot id: A0A2K8TEQ3
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12320
gene id: 53346:EM4838_RS12320
uniprot id: A0A2K8THR9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

53346:EM4838 RS07985
gene id: 53346:EM4838_RS07985
uniprot id: A0A1A6G4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

53346:EM4838 RS09500
gene id: 53346:EM4838_RS09500
uniprot id: A0A2K8TGF9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

53346:EM4838 RS03630
gene id: 53346:EM4838_RS03630
uniprot id: A0A1L8V3K9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

53346:EM4838 RS05190
gene id: 53346:EM4838_RS05190
uniprot id: A0A1A6G725
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

53346:EM4838 RS13910
gene id: 53346:EM4838_RS13910
uniprot id: A0A2K8TIQ8
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS09475
gene id: 53346:EM4838_RS09475
uniprot id: A0A1A6G9Y9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

53346:EM4838 RS10255
gene id: 53346:EM4838_RS10255
uniprot id: A0A2K8TH24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS15525
gene id: 53346:EM4838_RS15525
uniprot id: A0A2K8TJE7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS02450
gene id: 53346:EM4838_RS02450
uniprot id: A0A1I4NN16
names: Similarity
messages: Belongs to the UPF0173 family.

53346:EM4838 RS13475
gene id: 53346:EM4838_RS13475
uniprot id: A0A1A6G7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

53346:EM4838 RS06390
gene id: 53346:EM4838_RS06390
uniprot id: A0A1L8UTB9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

53346:EM4838 RS15335
gene id: 53346:EM4838_RS15335
uniprot id: A0A1L8V301
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

53346:EM4838 RS05235
gene id: 53346:EM4838_RS05235
uniprot id: A0A1L8V1J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

53346:EM4838 RS13710
gene id: 53346:EM4838_RS13710
uniprot id: A0A1L8V0E8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

53346:EM4838 RS06655
gene id: 53346:EM4838_RS06655
uniprot id: A0A1L8UV39
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS15295
gene id: 53346:EM4838_RS15295
uniprot id: A0A2K8TJ94
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05150
gene id: 53346:EM4838_RS05150
uniprot id: A0A1I4PDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14630
gene id: 53346:EM4838_RS14630
uniprot id: A0A1L8UN39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

53346:EM4838 RS09680
gene id: 53346:EM4838_RS09680
uniprot id: A0A2K8TGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

53346:EM4838 RS07530
gene id: 53346:EM4838_RS07530
uniprot id: A0A2K8TFA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

53346:EM4838 RS09170
gene id: 53346:EM4838_RS09170
uniprot id: A0A2K8TG56
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

53346:EM4838 RS09250
gene id: 53346:EM4838_RS09250
uniprot id: A0A1A6GAM4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

53346:EM4838 RS15140
gene id: 53346:EM4838_RS15140
uniprot id: A0A2K8TJG9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

53346:EM4838 RS05880
gene id: 53346:EM4838_RS05880
uniprot id: A0A1L8UMG8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

53346:EM4838 RS11785
gene id: 53346:EM4838_RS11785
uniprot id: A0A1A6GA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS09315
gene id: 53346:EM4838_RS09315
uniprot id: A0A1L8URE5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

53346:EM4838 RS07535
gene id: 53346:EM4838_RS07535
uniprot id: A0A2K8TH74
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

53346:EM4838 RS12605
gene id: 53346:EM4838_RS12605
uniprot id: A0A1A6G6F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

53346:EM4838 RS09765
gene id: 53346:EM4838_RS09765
uniprot id: A0A1L8UXW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS10020
gene id: 53346:EM4838_RS10020
uniprot id: A0A2K8TGK4
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

53346:EM4838 RS01050
gene id: 53346:EM4838_RS01050
uniprot id: A0A1L8V0L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

53346:EM4838 RS14740
gene id: 53346:EM4838_RS14740
uniprot id: A0A1A6G9G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

53346:EM4838 RS09155
gene id: 53346:EM4838_RS09155
uniprot id: A0A2K8TI14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

53346:EM4838 RS02055
gene id: 53346:EM4838_RS02055
uniprot id: A0A2K8TJU2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

53346:EM4838 RS04470
gene id: 53346:EM4838_RS04470
uniprot id: A0A1A6G7N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

53346:EM4838 RS05635
gene id: 53346:EM4838_RS05635
uniprot id: A0A2K8TE98
names: Similarity
messages: Belongs to the peptidase S16 family.

53346:EM4838 RS13505
gene id: 53346:EM4838_RS13505
uniprot id: A0A1A6G7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

53346:EM4838 RS11685
gene id: 53346:EM4838_RS11685
uniprot id: A0A2K8THF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14665
gene id: 53346:EM4838_RS14665
uniprot id: A0A1A6G9I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

53346:EM4838 RS03500
gene id: 53346:EM4838_RS03500
uniprot id: A0A1L8V3A8
names: Similarity
messages: Belongs to the DtxR/MntR family.

53346:EM4838 RS07405
gene id: 53346:EM4838_RS07405
uniprot id: A0A1I4JHA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

53346:EM4838 RS11410
gene id: 53346:EM4838_RS11410
uniprot id: A0A2K8THB1
names: Similarity
messages: Belongs to the ArsC family.

53346:EM4838 RS09505
gene id: 53346:EM4838_RS09505
uniprot id: A0A1L8UY87
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS09375
gene id: 53346:EM4838_RS09375
uniprot id: A0A1A6G9Y6
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS00860
gene id: 53346:EM4838_RS00860
uniprot id: A0A1V2UE92
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

53346:EM4838 RS10100
gene id: 53346:EM4838_RS10100
uniprot id: A0A1L8UST0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13280
gene id: 53346:EM4838_RS13280
uniprot id: A0A2K8TI73
names: Similarity
messages: Belongs to the peptidase C40 family.

53346:EM4838 RS11755
gene id: 53346:EM4838_RS11755
uniprot id: A0A1L8UM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

53346:EM4838 RS04030
gene id: 53346:EM4838_RS04030
uniprot id: A0A1L8V402
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

53346:EM4838 RS09645
gene id: 53346:EM4838_RS09645
uniprot id: A0A1L8UY37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS14860
gene id: 53346:EM4838_RS14860
uniprot id: A0A2K8TJT0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

53346:EM4838 RS09585
gene id: 53346:EM4838_RS09585
uniprot id: A0A1A6G872
names: Similarity
messages: Belongs to the UDPGP type 2 family.

53346:EM4838 RS07880
gene id: 53346:EM4838_RS07880
uniprot id: A0A2K8TFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

53346:EM4838 RS04630
gene id: 53346:EM4838_RS04630
uniprot id: A0A1A6GAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS11465
gene id: 53346:EM4838_RS11465
uniprot id: A0A2K8THC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

53346:EM4838 RS07500
gene id: 53346:EM4838_RS07500
uniprot id: A0A2K8TF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS11375
gene id: 53346:EM4838_RS11375
uniprot id: A0A2K8THH2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

53346:EM4838 RS02780
gene id: 53346:EM4838_RS02780
uniprot id: A0A1A6G9N8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

53346:EM4838 RS03935
gene id: 53346:EM4838_RS03935
uniprot id: A0A1L8V3U6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

53346:EM4838 RS07815
gene id: 53346:EM4838_RS07815
uniprot id: A0A1L8V1Y6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

53346:EM4838 RS05145
gene id: 53346:EM4838_RS05145
uniprot id: A0A2K8TFY8
names: Similarity
messages: Belongs to the UPF0346 family.

53346:EM4838 RS02610
gene id: 53346:EM4838_RS02610
uniprot id: A0A1I4MS38
names: Similarity
messages: Belongs to the fructosamine kinase family.

53346:EM4838 RS09065
gene id: 53346:EM4838_RS09065
uniprot id: A0A2K8TG31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00845
gene id: 53346:EM4838_RS00845
uniprot id: A0A2M9FRV6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS01085
gene id: 53346:EM4838_RS01085
uniprot id: A0A1V2UEF7
names: Similarity
messages: Belongs to the ArsC family.

53346:EM4838 RS14420
gene id: 53346:EM4838_RS14420
uniprot id: A0A2K8TJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

53346:EM4838 RS04445
gene id: 53346:EM4838_RS04445
uniprot id: A0A1A6G7N0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS11770
gene id: 53346:EM4838_RS11770
uniprot id: A0A1I4K2H8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

53346:EM4838 RS01000
gene id: 53346:EM4838_RS01000
uniprot id: A0A2K8TJH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12760
gene id: 53346:EM4838_RS12760
uniprot id: A0A2K8TI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14460
gene id: 53346:EM4838_RS14460
uniprot id: A0A1L8UN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12510
gene id: 53346:EM4838_RS12510
uniprot id: A0A2K8THW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS13345
gene id: 53346:EM4838_RS13345
uniprot id: A0A1I4Q951
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

53346:EM4838 RS01115
gene id: 53346:EM4838_RS01115
uniprot id: A0A2K8TC31
names: Similarity
messages: Belongs to the glutathione peroxidase family.

53346:EM4838 RS11930
gene id: 53346:EM4838_RS11930
uniprot id: A0A2K8TJQ5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05985
gene id: 53346:EM4838_RS05985
uniprot id: A0A242KYZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

53346:EM4838 RS02550
gene id: 53346:EM4838_RS02550
uniprot id: A0A1L8UJQ4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

53346:EM4838 RS15470
gene id: 53346:EM4838_RS15470
uniprot id: A0A1A6G482
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

53346:EM4838 RS11860
gene id: 53346:EM4838_RS11860
uniprot id: Q6EH13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

53346:EM4838 RS00725
gene id: 53346:EM4838_RS00725
uniprot id: A0A2M9FRV4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

53346:EM4838 RS12500
gene id: 53346:EM4838_RS12500
uniprot id: A0A1A6G5F9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00805
gene id: 53346:EM4838_RS00805
uniprot id: A0A2K8TBR6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09150
gene id: 53346:EM4838_RS09150
uniprot id: A0A2K8TG55
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

53346:EM4838 RS01525
gene id: 53346:EM4838_RS01525
uniprot id: A0A2K8TC52
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13445
gene id: 53346:EM4838_RS13445
uniprot id: A0A1L8V0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

53346:EM4838 RS05405
gene id: 53346:EM4838_RS05405
uniprot id: A0A242KYM4
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

53346:EM4838 RS14605
gene id: 53346:EM4838_RS14605
uniprot id: A0A1A6G4V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

53346:EM4838 RS11495
gene id: 53346:EM4838_RS11495
uniprot id: A0A2K8THC4
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14690
gene id: 53346:EM4838_RS14690
uniprot id: A0A1A6G9H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

53346:EM4838 RS08005
gene id: 53346:EM4838_RS08005
uniprot id: A0A1L8V2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

53346:EM4838 RS03730
gene id: 53346:EM4838_RS03730
uniprot id: A0A1L8V3M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

53346:EM4838 RS03770
gene id: 53346:EM4838_RS03770
uniprot id: A0A2K8TD98
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

53346:EM4838 RS11990
gene id: 53346:EM4838_RS11990
uniprot id: A0A2K8THT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06860
gene id: 53346:EM4838_RS06860
uniprot id: A0A1L8URU1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

53346:EM4838 RS15020
gene id: 53346:EM4838_RS15020
uniprot id: A0A1L8UJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

53346:EM4838 RS09105
gene id: 53346:EM4838_RS09105
uniprot id: A0A1L8UR32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS07960
gene id: 53346:EM4838_RS07960
uniprot id: A0A2K8THE6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

53346:EM4838 RS10815
gene id: 53346:EM4838_RS10815
uniprot id: A0A2K8TH06
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS10545
gene id: 53346:EM4838_RS10545
uniprot id: A0A1L8ULL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

53346:EM4838 RS03380
gene id: 53346:EM4838_RS03380
uniprot id: A0A1A6G699
names: Similarity
messages: Belongs to the TlyA family.

53346:EM4838 RS01380
gene id: 53346:EM4838_RS01380
uniprot id: A0A2M9FNF6
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

53346:EM4838 RS14650
gene id: 53346:EM4838_RS14650
uniprot id: A0A1A6G7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

53346:EM4838 RS01210
gene id: 53346:EM4838_RS01210
uniprot id: A0A2K8TC12
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS13520
gene id: 53346:EM4838_RS13520
uniprot id: A0A1L8V0J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS13210
gene id: 53346:EM4838_RS13210
uniprot id: A0A2K8TI60
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

53346:EM4838 RS08245
gene id: 53346:EM4838_RS08245
uniprot id: A0A1A6G786
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07945
gene id: 53346:EM4838_RS07945
uniprot id: A0A1L8V1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06000
gene id: 53346:EM4838_RS06000
uniprot id: A0A1A6GBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS13420
gene id: 53346:EM4838_RS13420
uniprot id: A0A2K8TIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

53346:EM4838 RS14780
gene id: 53346:EM4838_RS14780
uniprot id: A0A1A6G7T0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

53346:EM4838 RS14540
gene id: 53346:EM4838_RS14540
uniprot id: A0A1L8UN76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

53346:EM4838 RS15165
gene id: 53346:EM4838_RS15165
uniprot id: A0A1A6G8X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

53346:EM4838 RS13340
gene id: 53346:EM4838_RS13340
uniprot id: A0A1I4Q919
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

53346:EM4838 RS05310
gene id: 53346:EM4838_RS05310
uniprot id: A0A2K8TE17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12040
gene id: 53346:EM4838_RS12040
uniprot id: A0A2K8THU0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS15445
gene id: 53346:EM4838_RS15445
uniprot id: A0A2K8TJC1
names: Similarity
messages: Belongs to the DCK/DGK family.

53346:EM4838 RS15055
gene id: 53346:EM4838_RS15055
uniprot id: A0A2K8TJ61
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

53346:EM4838 RS09245
gene id: 53346:EM4838_RS09245
uniprot id: A0A2K8TGH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

53346:EM4838 RS02455
gene id: 53346:EM4838_RS02455
uniprot id: A0A1L8UZF8
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

53346:EM4838 RS02805
gene id: 53346:EM4838_RS02805
uniprot id: A0A1L8UVM6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS10435
gene id: 53346:EM4838_RS10435
uniprot id: A0A2K8TIP8
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

53346:EM4838 RS13390
gene id: 53346:EM4838_RS13390
uniprot id: A0A1I4Q9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02175
gene id: 53346:EM4838_RS02175
uniprot id: A0A2K8TEE4
names: Similarity
messages: Belongs to the PRORSD1 family.

53346:EM4838 RS13880
gene id: 53346:EM4838_RS13880
uniprot id: A0A2K8TJT6
names: Similarity
messages: Belongs to the FGGY kinase family.

53346:EM4838 RS07205
gene id: 53346:EM4838_RS07205
uniprot id: A0A1A6G9Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

53346:EM4838 RS12855
gene id: 53346:EM4838_RS12855
uniprot id: A0A2T5DBW9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

53346:EM4838 RS07155
gene id: 53346:EM4838_RS07155
uniprot id: A0A1L8URH6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

53346:EM4838 RS03890
gene id: 53346:EM4838_RS03890
uniprot id: A0A1L8V3V3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

53346:EM4838 RS15585
gene id: 53346:EM4838_RS15585
uniprot id: A0A1I4L3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08125
gene id: 53346:EM4838_RS08125
uniprot id: A0A2K8TFK0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS10050
gene id: 53346:EM4838_RS10050
uniprot id: A0A1A6GB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

53346:EM4838 RS13455
gene id: 53346:EM4838_RS13455
uniprot id: A0A1A6G7L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

53346:EM4838 RS05215
gene id: 53346:EM4838_RS05215
uniprot id: A0A1A6G719
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

53346:EM4838 RS09790
gene id: 53346:EM4838_RS09790
uniprot id: A0A1A6GD02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

53346:EM4838 RS06880
gene id: 53346:EM4838_RS06880
uniprot id: A0A2K8TEW0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

53346:EM4838 RS08335
gene id: 53346:EM4838_RS08335
uniprot id: A0A1L8UKJ7
names: Similarity
messages: Belongs to the asparagine synthetase family.

53346:EM4838 RS14285
gene id: 53346:EM4838_RS14285
uniprot id: A0A2K8TIQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

53346:EM4838 RS06535
gene id: 53346:EM4838_RS06535
uniprot id: A0A2K8TEU3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS08700
gene id: 53346:EM4838_RS08700
uniprot id: A0A1A6G9Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS04870
gene id: 53346:EM4838_RS04870
uniprot id: A0A1I4PHF6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13215
gene id: 53346:EM4838_RS13215
uniprot id: A0A1A6G8E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

53346:EM4838 RS01365
gene id: 53346:EM4838_RS01365
uniprot id: A0A2K8TC69
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS02910
gene id: 53346:EM4838_RS02910
uniprot id: A0A242KXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

53346:EM4838 RS02420
gene id: 53346:EM4838_RS02420
uniprot id: A0A2K8TCN4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

53346:EM4838 RS10800
gene id: 53346:EM4838_RS10800
uniprot id: A0A2K8THC1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

53346:EM4838 RS08910
gene id: 53346:EM4838_RS08910
uniprot id: A0A1L8UX18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

53346:EM4838 RS10620
gene id: 53346:EM4838_RS10620
uniprot id: A0A1L8UMI2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

53346:EM4838 RS05890
gene id: 53346:EM4838_RS05890
uniprot id: A0A1A6GBV1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

53346:EM4838 RS09360
gene id: 53346:EM4838_RS09360
uniprot id: A0A2K8TI52
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS05555
gene id: 53346:EM4838_RS05555
uniprot id: A0A1L8UU30
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

53346:EM4838 RS03620
gene id: 53346:EM4838_RS03620
uniprot id: A0A1A6G6I2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

53346:EM4838 RS10745
gene id: 53346:EM4838_RS10745
uniprot id: A0A1I4MC36
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

53346:EM4838 RS05495
gene id: 53346:EM4838_RS05495
uniprot id: A0A1I4LM07
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS06995
gene id: 53346:EM4838_RS06995
uniprot id: A0A2K8TF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

53346:EM4838 RS00455
gene id: 53346:EM4838_RS00455
uniprot id: A0A2K8TBL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS10820
gene id: 53346:EM4838_RS10820
uniprot id: A0A2K8TH02
names: Similarity
messages: Belongs to the peptidase M20A family.

53346:EM4838 RS00245
gene id: 53346:EM4838_RS00245
uniprot id: A0A1L8V388
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14595
gene id: 53346:EM4838_RS14595
uniprot id: A0A1L8UNH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

53346:EM4838 RS13845
gene id: 53346:EM4838_RS13845
uniprot id: A0A1A6GBK9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

53346:EM4838 RS06915
gene id: 53346:EM4838_RS06915
uniprot id: A0A1A6G7Y4
names: Similarity
messages: Belongs to the asp23 family.

53346:EM4838 RS15610
gene id: 53346:EM4838_RS15610
uniprot id: A0A1L8V333
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS00920
gene id: 53346:EM4838_RS00920
uniprot id: A0A2K8TBW2
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS00240
gene id: 53346:EM4838_RS00240
uniprot id: A0A1L8V2R0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

53346:EM4838 RS13715
gene id: 53346:EM4838_RS13715
uniprot id: A0A2K8TIG7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

53346:EM4838 RS01900
gene id: 53346:EM4838_RS01900
uniprot id: A0A2K8TCN0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06380
gene id: 53346:EM4838_RS06380
uniprot id: A0A242KZ68
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

53346:EM4838 RS12490
gene id: 53346:EM4838_RS12490
uniprot id: A0A1I4PMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

53346:EM4838 RS12905
gene id: 53346:EM4838_RS12905
uniprot id: A0A2K8TI29
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS01740
gene id: 53346:EM4838_RS01740
uniprot id: A0A2K8TCK0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14680
gene id: 53346:EM4838_RS14680
uniprot id: A0A1A6G7U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

53346:EM4838 RS13375
gene id: 53346:EM4838_RS13375
uniprot id: A0A1A6GAK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

53346:EM4838 RS14875
gene id: 53346:EM4838_RS14875
uniprot id: A0A1A6G9E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS05450
gene id: 53346:EM4838_RS05450
uniprot id: A0A1L8UUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

53346:EM4838 RS02795
gene id: 53346:EM4838_RS02795
uniprot id: A0A2K8TCS8
names: Subcellular Location Annotation
messages: Cell membrane

53346:EM4838 RS14770
gene id: 53346:EM4838_RS14770
uniprot id: A0A1A6G6T0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS08090
gene id: 53346:EM4838_RS08090
uniprot id: A0A2K8TFJ6
names: Similarity
messages: Belongs to the carbamate kinase family.

53346:EM4838 RS14510
gene id: 53346:EM4838_RS14510
uniprot id: A0A2K8TJ14
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

53346:EM4838 RS00575
gene id: 53346:EM4838_RS00575
uniprot id: A0A2K8TL97
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06345
gene id: 53346:EM4838_RS06345
uniprot id: A0A2K8TEK8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS07725
gene id: 53346:EM4838_RS07725
uniprot id: A0A1L8V2I2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

53346:EM4838 RS00230
gene id: 53346:EM4838_RS00230
uniprot id: A0A2K8TJT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS03475
gene id: 53346:EM4838_RS03475
uniprot id: A0A1I4MYL2
names: Similarity
messages: Belongs to the YggT family.

53346:EM4838 RS08110
gene id: 53346:EM4838_RS08110
uniprot id: A0A2M9FQV2
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS15415
gene id: 53346:EM4838_RS15415
uniprot id: A0A1L8V2Z4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

53346:EM4838 RS14360
gene id: 53346:EM4838_RS14360
uniprot id: A0A1L8UPB7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS12255
gene id: 53346:EM4838_RS12255
uniprot id: A0A1A6G6L0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

53346:EM4838 RS10265
gene id: 53346:EM4838_RS10265
uniprot id: A0A2K8TIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08140
gene id: 53346:EM4838_RS08140
uniprot id: A0A2K8TFK6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

53346:EM4838 RS03490
gene id: 53346:EM4838_RS03490
uniprot id: A0A1L8V471
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

53346:EM4838 RS03455
gene id: 53346:EM4838_RS03455
uniprot id: A0A2K8TD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

53346:EM4838 RS14290
gene id: 53346:EM4838_RS14290
uniprot id: A0A1A6GC64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

53346:EM4838 RS10205
gene id: 53346:EM4838_RS10205
uniprot id: A0A1L8USF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

53346:EM4838 RS14950
gene id: 53346:EM4838_RS14950
uniprot id: A0A1I4ML56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

53346:EM4838 RS02735
gene id: 53346:EM4838_RS02735
uniprot id: A0A1L8UV75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS06910
gene id: 53346:EM4838_RS06910
uniprot id: A0A1A6G889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

53346:EM4838 RS03865
gene id: 53346:EM4838_RS03865
uniprot id: A0A2K8TDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

53346:EM4838 RS01955
gene id: 53346:EM4838_RS01955
uniprot id: A0A1L8UZK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS10085
gene id: 53346:EM4838_RS10085
uniprot id: A0A2K8TGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

53346:EM4838 RS01975
gene id: 53346:EM4838_RS01975
uniprot id: A0A2K8TCC7
names: Similarity
messages: Belongs to the manganese catalase family.

53346:EM4838 RS09035
gene id: 53346:EM4838_RS09035
uniprot id: A0A1L8UX72
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07380
gene id: 53346:EM4838_RS07380
uniprot id: A0A2K8TF73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

53346:EM4838 RS11170
gene id: 53346:EM4838_RS11170
uniprot id: A0A242L1X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

53346:EM4838 RS11940
gene id: 53346:EM4838_RS11940
uniprot id: A0A2K8TJF3
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS14725
gene id: 53346:EM4838_RS14725
uniprot id: A0A1A6G839
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

53346:EM4838 RS10990
gene id: 53346:EM4838_RS10990
uniprot id: A0A1L8UTG8
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS01635
gene id: 53346:EM4838_RS01635
uniprot id: A0A2K8TC73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

53346:EM4838 RS07740
gene id: 53346:EM4838_RS07740
uniprot id: A0A2K8TJN7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS14245
gene id: 53346:EM4838_RS14245
uniprot id: A0A1A6GC73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

53346:EM4838 RS05300
gene id: 53346:EM4838_RS05300
uniprot id: A0A1L8V284
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS15405
gene id: 53346:EM4838_RS15405
uniprot id: A0A1I4L1X4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

53346:EM4838 RS13440
gene id: 53346:EM4838_RS13440
uniprot id: A0A1I4Q7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

53346:EM4838 RS02070
gene id: 53346:EM4838_RS02070
uniprot id: A0A2K8TCE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01240
gene id: 53346:EM4838_RS01240
uniprot id: A0A1L8UYS8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

53346:EM4838 RS09290
gene id: 53346:EM4838_RS09290
uniprot id: A0A2K8TGB9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

53346:EM4838 RS08085
gene id: 53346:EM4838_RS08085
uniprot id: A0A2K8TFN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

53346:EM4838 RS14585
gene id: 53346:EM4838_RS14585
uniprot id: A0A1I4MHD5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06010
gene id: 53346:EM4838_RS06010
uniprot id: A0A1A6GAB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

53346:EM4838 RS16105
gene id: 53346:EM4838_RS16105
uniprot id: A0A2K8TK14
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

53346:EM4838 RS11690
gene id: 53346:EM4838_RS11690
uniprot id: A0A1L8UM78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

53346:EM4838 RS07790
gene id: 53346:EM4838_RS07790
uniprot id: A0A1A6G5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

53346:EM4838 RS05920
gene id: 53346:EM4838_RS05920
uniprot id: A0A2K8TLD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Belongs to the RNase PH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

53346:EM4838 RS10245
gene id: 53346:EM4838_RS10245
uniprot id: A0A1A6G635
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

53346:EM4838 RS05915
gene id: 53346:EM4838_RS05915
uniprot id: A0A2K8TEI2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

53346:EM4838 RS05180
gene id: 53346:EM4838_RS05180
uniprot id: A0A2K8TE55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

53346:EM4838 RS15550
gene id: 53346:EM4838_RS15550
uniprot id: A0A2K8TJL9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

53346:EM4838 RS12650
gene id: 53346:EM4838_RS12650
uniprot id: A0A2K8TI61
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

53346:EM4838 RS03585
gene id: 53346:EM4838_RS03585
uniprot id: A0A1A6GBL5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

53346:EM4838 RS08705
gene id: 53346:EM4838_RS08705
uniprot id: A0A1L8UX02
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

53346:EM4838 RS11585
gene id: 53346:EM4838_RS11585
uniprot id: A0A2K8THL2
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09935
gene id: 53346:EM4838_RS09935
uniprot id: A0A1A6GA84
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS15270
gene id: 53346:EM4838_RS15270
uniprot id: A0A1L8V2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

53346:EM4838 RS04740
gene id: 53346:EM4838_RS04740
uniprot id: A0A2K8TDW7
names: Similarity
messages: Belongs to the ThiD family.

53346:EM4838 RS03425
gene id: 53346:EM4838_RS03425
uniprot id: A0A1A6GBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

53346:EM4838 RS08315
gene id: 53346:EM4838_RS08315
uniprot id: A0A2K8TFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

53346:EM4838 RS08645
gene id: 53346:EM4838_RS08645
uniprot id: A0A1A6GBX3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS00115
gene id: 53346:EM4838_RS00115
uniprot id: A0A2K8TBF8
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

53346:EM4838 RS00995
gene id: 53346:EM4838_RS00995
uniprot id: A0A2K8TC74
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

53346:EM4838 RS06700
gene id: 53346:EM4838_RS06700
uniprot id: A0A2K8TEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

53346:EM4838 RS08000
gene id: 53346:EM4838_RS08000
uniprot id: A0A1A6G9B4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS15065
gene id: 53346:EM4838_RS15065
uniprot id: A0A2K8TJ60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

53346:EM4838 RS07455
gene id: 53346:EM4838_RS07455
uniprot id: A0A1A6G830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

53346:EM4838 RS15310
gene id: 53346:EM4838_RS15310
uniprot id: A0A1I4L0N8
names: Similarity
messages: Belongs to the PemK/MazF family.

53346:EM4838 RS12300
gene id: 53346:EM4838_RS12300
uniprot id: A0A2K8THS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

53346:EM4838 RS00900
gene id: 53346:EM4838_RS00900
uniprot id: A0A1A6GCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08680
gene id: 53346:EM4838_RS08680
uniprot id: A0A1A6G9S5
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS14885
gene id: 53346:EM4838_RS14885
uniprot id: A0A1L8UN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02000
gene id: 53346:EM4838_RS02000
uniprot id: A0A1A6G7Z8
names: Similarity
messages: Belongs to the TelA family.

53346:EM4838 RS07645
gene id: 53346:EM4838_RS07645
uniprot id: A0A1L8V2C3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

53346:EM4838 RS03670
gene id: 53346:EM4838_RS03670
uniprot id: A0A1L8V3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

53346:EM4838 RS15630
gene id: 53346:EM4838_RS15630
uniprot id: A0A2K8TBS0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

53346:EM4838 RS06620
gene id: 53346:EM4838_RS06620
uniprot id: A0A242L0E8
names: Similarity
messages: Belongs to the ThiD family.

53346:EM4838 RS09800
gene id: 53346:EM4838_RS09800
uniprot id: A0A1A6GBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

53346:EM4838 RS12555
gene id: 53346:EM4838_RS12555
uniprot id: A0A2K8TJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

53346:EM4838 RS02845
gene id: 53346:EM4838_RS02845
uniprot id: A0A1L8UVB7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

53346:EM4838 RS09590
gene id: 53346:EM4838_RS09590
uniprot id: A0A2K8TGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

53346:EM4838 RS15095
gene id: 53346:EM4838_RS15095
uniprot id: A0A1L8V2U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

53346:EM4838 RS14230
gene id: 53346:EM4838_RS14230
uniprot id: A0A1A6GAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

53346:EM4838 RS01135
gene id: 53346:EM4838_RS01135
uniprot id: A0A1L8UYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

53346:EM4838 RS03785
gene id: 53346:EM4838_RS03785
uniprot id: A0A1L8V3T2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

53346:EM4838 RS13325
gene id: 53346:EM4838_RS13325
uniprot id: A0A1A6GD57
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

53346:EM4838 RS12025
gene id: 53346:EM4838_RS12025
uniprot id: A0A1A6GBA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

53346:EM4838 RS09160
gene id: 53346:EM4838_RS09160
uniprot id: A0A2K8TG46
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

53346:EM4838 RS15290
gene id: 53346:EM4838_RS15290
uniprot id: A0A1A6G664
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

53346:EM4838 RS04810
gene id: 53346:EM4838_RS04810
uniprot id: A0A1A6G8J6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

53346:EM4838 RS08790
gene id: 53346:EM4838_RS08790
uniprot id: A0A2K8TG33
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

53346:EM4838 RS15640
gene id: 53346:EM4838_RS15640
uniprot id: A0A1L8V3G9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

53346:EM4838 RS10225
gene id: 53346:EM4838_RS10225
uniprot id: A0A1A6G4T8
names: Similarity
messages: Belongs to the UPF0297 family.

53346:EM4838 RS02665
gene id: 53346:EM4838_RS02665
uniprot id: A0A1L8UVF1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

53346:EM4838 RS11385
gene id: 53346:EM4838_RS11385
uniprot id: A0A1A6G3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

53346:EM4838 RS15965
gene id: 53346:EM4838_RS15965
uniprot id: A0A2K8TK50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

53346:EM4838 RS02395
gene id: 53346:EM4838_RS02395
uniprot id: A0A2K8TEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

53346:EM4838 RS12050
gene id: 53346:EM4838_RS12050
uniprot id: A0A1L8V1E1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

53346:EM4838 RS11595
gene id: 53346:EM4838_RS11595
uniprot id: A0A2K8THQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

53346:EM4838 RS00095
gene id: 53346:EM4838_RS00095
uniprot id: A0A2K8TBS0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

53346:EM4838 RS14155
gene id: 53346:EM4838_RS14155
uniprot id: A0A1L8UJK7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

53346:EM4838 RS03435
gene id: 53346:EM4838_RS03435
uniprot id: A0A1I4MXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS11550
gene id: 53346:EM4838_RS11550
uniprot id: A0A1L8UW26
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

53346:EM4838 RS11820
gene id: 53346:EM4838_RS11820
uniprot id: A0A1L8UM36
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

53346:EM4838 RS01445
gene id: 53346:EM4838_RS01445
uniprot id: A0A2K8TCF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS06215
gene id: 53346:EM4838_RS06215
uniprot id: A0A2K8TEK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

53346:EM4838 RS05560
gene id: 53346:EM4838_RS05560
uniprot id: A0A1L8UU15
names: Similarity
messages: Belongs to the UPF0223 family.

53346:EM4838 RS13890
gene id: 53346:EM4838_RS13890
uniprot id: A0A1A6G9Q9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

53346:EM4838 RS11205
gene id: 53346:EM4838_RS11205
uniprot id: A0A1A6G3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06270
gene id: 53346:EM4838_RS06270
uniprot id: A0A2K8TEQ7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

53346:EM4838 RS13730
gene id: 53346:EM4838_RS13730
uniprot id: A0A2K8TIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

53346:EM4838 RS11430
gene id: 53346:EM4838_RS11430
uniprot id: A0A2K8THI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS04915
gene id: 53346:EM4838_RS04915
uniprot id: A0A1A6G5W7
names: Similarity
messages: Belongs to the Fur family.

53346:EM4838 RS03835
gene id: 53346:EM4838_RS03835
uniprot id: A0A1L8V3P4
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS02280
gene id: 53346:EM4838_RS02280
uniprot id: A0A1L8UZA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14945
gene id: 53346:EM4838_RS14945
uniprot id: A0A242KVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

53346:EM4838 RS02925
gene id: 53346:EM4838_RS02925
uniprot id: A0A1L8UV68
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

53346:EM4838 RS14670
gene id: 53346:EM4838_RS14670
uniprot id: A0A1A6G6V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

53346:EM4838 RS08165
gene id: 53346:EM4838_RS08165
uniprot id: A0A1A6G7H6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05195
gene id: 53346:EM4838_RS05195
uniprot id: A0A1A6G6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

53346:EM4838 RS11555
gene id: 53346:EM4838_RS11555
uniprot id: A0A1I4K4Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

53346:EM4838 RS12880
gene id: 53346:EM4838_RS12880
uniprot id: A0A1L8UQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS10215
gene id: 53346:EM4838_RS10215
uniprot id: A0A1A6G5U7
names: Similarity
messages: Belongs to the UPF0473 family.

53346:EM4838 RS12325
gene id: 53346:EM4838_RS12325
uniprot id: A0A1A6G6U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS03895
gene id: 53346:EM4838_RS03895
uniprot id: A0A1A6G8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

53346:EM4838 RS07785
gene id: 53346:EM4838_RS07785
uniprot id: A0A1A6G5R3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

53346:EM4838 RS11850
gene id: 53346:EM4838_RS11850
uniprot id: A0A2K8THJ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS11415
gene id: 53346:EM4838_RS11415
uniprot id: A0A1A6G514
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06365
gene id: 53346:EM4838_RS06365
uniprot id: A0A1A6G9M5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS06350
gene id: 53346:EM4838_RS06350
uniprot id: A0A242L098
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

53346:EM4838 RS05600
gene id: 53346:EM4838_RS05600
uniprot id: A0A1I4LJJ3
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09220
gene id: 53346:EM4838_RS09220
uniprot id: A0A1A6G7X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

53346:EM4838 RS03315
gene id: 53346:EM4838_RS03315
uniprot id: A0A1L8V3G5
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS00865
gene id: 53346:EM4838_RS00865
uniprot id: A0A2K8TBV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

53346:EM4838 RS08095
gene id: 53346:EM4838_RS08095
uniprot id: A0A1L8ULT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

53346:EM4838 RS03965
gene id: 53346:EM4838_RS03965
uniprot id: A0A1L8V472
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

53346:EM4838 RS03860
gene id: 53346:EM4838_RS03860
uniprot id: A0A1I4LYT6
names: Similarity
messages: Belongs to the acetyltransferase family.

53346:EM4838 RS01430
gene id: 53346:EM4838_RS01430
uniprot id: A0A2K8TC54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14805
gene id: 53346:EM4838_RS14805
uniprot id: A0A2K8TJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02545
gene id: 53346:EM4838_RS02545
uniprot id: A0A2K8TCQ9
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS01545
gene id: 53346:EM4838_RS01545
uniprot id: A0A1V2UIR7
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

53346:EM4838 RS08010
gene id: 53346:EM4838_RS08010
uniprot id: A0A1A6GAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

53346:EM4838 RS14830
gene id: 53346:EM4838_RS14830
uniprot id: A0A1A6G7S4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

53346:EM4838 RS15355
gene id: 53346:EM4838_RS15355
uniprot id: A0A1A6G5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

53346:EM4838 RS10070
gene id: 53346:EM4838_RS10070
uniprot id: A0A1L8USI6
names: Similarity
messages: Belongs to the FBPase class 3 family.

53346:EM4838 RS15030
gene id: 53346:EM4838_RS15030
uniprot id: A0A1A6GAP6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS05140
gene id: 53346:EM4838_RS05140
uniprot id: A0A2K8TE03
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

53346:EM4838 RS07755
gene id: 53346:EM4838_RS07755
uniprot id: A0A2K8TFD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS03575
gene id: 53346:EM4838_RS03575
uniprot id: A0A1L8V3R3
names: Similarity
messages: Belongs to the peptidase M29 family.

53346:EM4838 RS05475
gene id: 53346:EM4838_RS05475
uniprot id: A0A1L8UUD4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

53346:EM4838 RS01800
gene id: 53346:EM4838_RS01800
uniprot id: A0A2K8TCA4
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

53346:EM4838 RS07040
gene id: 53346:EM4838_RS07040
uniprot id: A0A1L8URK9
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS01370
gene id: 53346:EM4838_RS01370
uniprot id: A0A2K8TC47
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

53346:EM4838 RS12900
gene id: 53346:EM4838_RS12900
uniprot id: A0A1L8UQ86
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

53346:EM4838 RS12540
gene id: 53346:EM4838_RS12540
uniprot id: A0A2K8TI36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS00175
gene id: 53346:EM4838_RS00175
uniprot id: A0A2K8TBG5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS04840
gene id: 53346:EM4838_RS04840
uniprot id: A0A2K8TDV1
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12175
gene id: 53346:EM4838_RS12175
uniprot id: A0A2K8TJI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

53346:EM4838 RS03415
gene id: 53346:EM4838_RS03415
uniprot id: A0A2K8TJI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

53346:EM4838 RS15090
gene id: 53346:EM4838_RS15090
uniprot id: A0A2K8TJF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

53346:EM4838 RS08320
gene id: 53346:EM4838_RS08320
uniprot id: A0A2K8TFP3
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

53346:EM4838 RS06315
gene id: 53346:EM4838_RS06315
uniprot id: A0A2K8TER6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

53346:EM4838 RS10055
gene id: 53346:EM4838_RS10055
uniprot id: A0A2K8TGM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

53346:EM4838 RS13725
gene id: 53346:EM4838_RS13725
uniprot id: A0A2K8TIM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
messages: Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14035
gene id: 53346:EM4838_RS14035
uniprot id: A0A2K8TKF2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

53346:EM4838 RS02865
gene id: 53346:EM4838_RS02865
uniprot id: A0A1A6G9D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

53346:EM4838 RS11775
gene id: 53346:EM4838_RS11775
uniprot id: A0A2K8TJC4
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

53346:EM4838 RS11185
gene id: 53346:EM4838_RS11185
uniprot id: A0A1L8UWG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

53346:EM4838 RS15275
gene id: 53346:EM4838_RS15275
uniprot id: A0A1L8V369
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

53346:EM4838 RS09940
gene id: 53346:EM4838_RS09940
uniprot id: A0A1A6GCT2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

53346:EM4838 RS06195
gene id: 53346:EM4838_RS06195
uniprot id: A0A1L8UTB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

53346:EM4838 RS13285
gene id: 53346:EM4838_RS13285
uniprot id: A0A1A6GB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

53346:EM4838 RS01175
gene id: 53346:EM4838_RS01175
uniprot id: A0A2K8TCA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS05655
gene id: 53346:EM4838_RS05655
uniprot id: A0A1A6G4X5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

53346:EM4838 RS06635
gene id: 53346:EM4838_RS06635
uniprot id: A0A2K8TEW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

53346:EM4838 RS12180
gene id: 53346:EM4838_RS12180
uniprot id: A0A1A6G6M4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

53346:EM4838 RS15590
gene id: 53346:EM4838_RS15590
uniprot id: A0A2K8TJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

53346:EM4838 RS06765
gene id: 53346:EM4838_RS06765
uniprot id: A0A1L8UUR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

53346:EM4838 RS01165
gene id: 53346:EM4838_RS01165
uniprot id: A0A1A6G8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

53346:EM4838 RS11270
gene id: 53346:EM4838_RS11270
uniprot id: A0A2K8TJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

53346:EM4838 RS06520
gene id: 53346:EM4838_RS06520
uniprot id: A0A2K8TEP1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

53346:EM4838 RS14240
gene id: 53346:EM4838_RS14240
uniprot id: A0A1A6GAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

53346:EM4838 RS00225
gene id: 53346:EM4838_RS00225
uniprot id: A0A242KVV9
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS11565
gene id: 53346:EM4838_RS11565
uniprot id: A0A1L8UW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

53346:EM4838 RS15435
gene id: 53346:EM4838_RS15435
uniprot id: A0A242KVQ9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

53346:EM4838 RS04725
gene id: 53346:EM4838_RS04725
uniprot id: A0A2K8TDR0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS15025
gene id: 53346:EM4838_RS15025
uniprot id: A0A1A6G9E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

53346:EM4838 RS14910
gene id: 53346:EM4838_RS14910
uniprot id: A0A2K8TJ26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

53346:EM4838 RS08155
gene id: 53346:EM4838_RS08155
uniprot id: A0A1L8ULS7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

53346:EM4838 RS06425
gene id: 53346:EM4838_RS06425
uniprot id: A0A2K8TET7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

53346:EM4838 RS03485
gene id: 53346:EM4838_RS03485
uniprot id: A0A1A6GAA1
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS08280
gene id: 53346:EM4838_RS08280
uniprot id: A0A1A6GDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

53346:EM4838 RS13260
gene id: 53346:EM4838_RS13260
uniprot id: A0A1A6GB48
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14640
gene id: 53346:EM4838_RS14640
uniprot id: A0A1A6G6V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

53346:EM4838 RS11600
gene id: 53346:EM4838_RS11600
uniprot id: A0A1L8UW21
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

53346:EM4838 RS09815
gene id: 53346:EM4838_RS09815
uniprot id: A0A1L8UXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

53346:EM4838 RS05510
gene id: 53346:EM4838_RS05510
uniprot id: A0A2K8TE62
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

53346:EM4838 RS15075
gene id: 53346:EM4838_RS15075
uniprot id: A0A1L8V2V2
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS12645
gene id: 53346:EM4838_RS12645
uniprot id: A0A1L8UNB2
names: Similarity
messages: Belongs to the GSP E family.

53346:EM4838 RS12835
gene id: 53346:EM4838_RS12835
uniprot id: A0A2K8TJW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

53346:EM4838 RS01080
gene id: 53346:EM4838_RS01080
uniprot id: A0A2K8TBW4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

53346:EM4838 RS02660
gene id: 53346:EM4838_RS02660
uniprot id: A0A1L8UVQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

53346:EM4838 RS02895
gene id: 53346:EM4838_RS02895
uniprot id: A0A2K8TCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS09855
gene id: 53346:EM4838_RS09855
uniprot id: A0A2K8TGK7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

53346:EM4838 RS05935
gene id: 53346:EM4838_RS05935
uniprot id: A0A1A6GAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

53346:EM4838 RS09795
gene id: 53346:EM4838_RS09795
uniprot id: A0A1A6GAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

53346:EM4838 RS00715
gene id: 53346:EM4838_RS00715
uniprot id: A0A1A6G5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

53346:EM4838 RS02335
gene id: 53346:EM4838_RS02335
uniprot id: A0A2K8TCV6
names: Similarity
messages: Belongs to the PemK/MazF family.

53346:EM4838 RS13300
gene id: 53346:EM4838_RS13300
uniprot id: A0A2K8TI84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

53346:EM4838 RS12640
gene id: 53346:EM4838_RS12640
uniprot id: A0A2K8THY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

53346:EM4838 RS14730
gene id: 53346:EM4838_RS14730
uniprot id: A0A1A6G7T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

53346:EM4838 RS13850
gene id: 53346:EM4838_RS13850
uniprot id: A0A1A6GAI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

53346:EM4838 RS11135
gene id: 53346:EM4838_RS11135
uniprot id: A0A2K8THD5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

53346:EM4838 RS12765
gene id: 53346:EM4838_RS12765
uniprot id: A0A1A6GAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS13510
gene id: 53346:EM4838_RS13510
uniprot id: A0A2K8TIC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

53346:EM4838 RS05860
gene id: 53346:EM4838_RS05860
uniprot id: A0A1L8UMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS05910
gene id: 53346:EM4838_RS05910
uniprot id: A0A1L8UME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12115
gene id: 53346:EM4838_RS12115
uniprot id: A0A1A6G8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

53346:EM4838 RS16250
gene id: 53346:EM4838_RS16250
uniprot id: A0A2K8TKA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

53346:EM4838 RS06495
gene id: 53346:EM4838_RS06495
uniprot id: A0A2K8TEU5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS12590
gene id: 53346:EM4838_RS12590
uniprot id: A0A1L8UNK9
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06845
gene id: 53346:EM4838_RS06845
uniprot id: A0A1I4J6Z4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

53346:EM4838 RS02615
gene id: 53346:EM4838_RS02615
uniprot id: A0A1L8UVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

53346:EM4838 RS14720
gene id: 53346:EM4838_RS14720
uniprot id: A0A1A6G6U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

53346:EM4838 RS02305
gene id: 53346:EM4838_RS02305
uniprot id: A0A1I4NL43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

53346:EM4838 RS12190
gene id: 53346:EM4838_RS12190
uniprot id: A0A2K8THQ0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

53346:EM4838 RS14710
gene id: 53346:EM4838_RS14710
uniprot id: A0A1A6G6S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

53346:EM4838 RS03655
gene id: 53346:EM4838_RS03655
uniprot id: A0A2K8TD81
names: Similarity
messages: Belongs to the ABC transporter superfamily.

53346:EM4838 RS08720
gene id: 53346:EM4838_RS08720
uniprot id: A0A1L8UWU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS03340
gene id: 53346:EM4838_RS03340
uniprot id: A0A1A6G7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

53346:EM4838 RS13255
gene id: 53346:EM4838_RS13255
uniprot id: A0A2K8TI77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

53346:EM4838 RS11030
gene id: 53346:EM4838_RS11030
uniprot id: A0A2K8TH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS05905
gene id: 53346:EM4838_RS05905
uniprot id: A0A1L8UMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS09710
gene id: 53346:EM4838_RS09710
uniprot id: A0A2K8TJN3
names: Similarity
messages: Belongs to the IMPACT family.

53346:EM4838 RS14685
gene id: 53346:EM4838_RS14685
uniprot id: A0A1A6G6S6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

53346:EM4838 RS06240
gene id: 53346:EM4838_RS06240
uniprot id: A0A1L8UTQ5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07865
gene id: 53346:EM4838_RS07865
uniprot id: A0A1L8V1X8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

53346:EM4838 RS05245
gene id: 53346:EM4838_RS05245
uniprot id: A0A1L8V270
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS04055
gene id: 53346:EM4838_RS04055
uniprot id: A0A2K8TLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

53346:EM4838 RS12005
gene id: 53346:EM4838_RS12005
uniprot id: A0A2K8TJF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

53346:EM4838 RS09520
gene id: 53346:EM4838_RS09520
uniprot id: A0A2K8TGB8
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS04950
gene id: 53346:EM4838_RS04950
uniprot id: A0A1A6G6V8
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13635
gene id: 53346:EM4838_RS13635
uniprot id: A0A2K8TIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaA family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS03970
gene id: 53346:EM4838_RS03970
uniprot id: A0A1L8V485
names: Function
names: Similarity
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

53346:EM4838 RS14275
gene id: 53346:EM4838_RS14275
uniprot id: A0A1A6GBY5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

53346:EM4838 RS08135
gene id: 53346:EM4838_RS08135
uniprot id: A0A2K8TFP2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

53346:EM4838 RS14265
gene id: 53346:EM4838_RS14265
uniprot id: A0A2K8TJ03
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

53346:EM4838 RS04050
gene id: 53346:EM4838_RS04050
uniprot id: A0A1L8V4G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS12960
gene id: 53346:EM4838_RS12960
uniprot id: A0A1L8UQF1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

53346:EM4838 RS03975
gene id: 53346:EM4838_RS03975
uniprot id: A0A2K8TDE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS13515
gene id: 53346:EM4838_RS13515
uniprot id: A0A1A6G8Y8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

53346:EM4838 RS11365
gene id: 53346:EM4838_RS11365
uniprot id: A0A1L8UW59
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

53346:EM4838 RS06310
gene id: 53346:EM4838_RS06310
uniprot id: A0A1L8UT99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

53346:EM4838 RS02225
gene id: 53346:EM4838_RS02225
uniprot id: A0A1L8UZI2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

53346:EM4838 RS11315
gene id: 53346:EM4838_RS11315
uniprot id: A0A2K8TH85
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

53346:EM4838 RS04900
gene id: 53346:EM4838_RS04900
uniprot id: A0A1A6G5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

53346:EM4838 RS03635
gene id: 53346:EM4838_RS03635
uniprot id: A0A2K8TDI3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

53346:EM4838 RS09755
gene id: 53346:EM4838_RS09755
uniprot id: A0A242L2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

53346:EM4838 RS00870
gene id: 53346:EM4838_RS00870
uniprot id: A0A2M9FRW0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS00475
gene id: 53346:EM4838_RS00475
uniprot id: A0A1L8V3A6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

53346:EM4838 RS06900
gene id: 53346:EM4838_RS06900
uniprot id: A0A2K8TEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08655
gene id: 53346:EM4838_RS08655
uniprot id: A0A1L8UWT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

53346:EM4838 RS02445
gene id: 53346:EM4838_RS02445
uniprot id: A0A1L8UZH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS16265
gene id: 53346:EM4838_RS16265
uniprot id: A0A2K8TK34
names: Subcellular Location Annotation
messages: Cell membrane

53346:EM4838 RS02525
gene id: 53346:EM4838_RS02525
uniprot id: A0A1L8UJN3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.

53346:EM4838 RS15970
gene id: 53346:EM4838_RS15970
uniprot id: A0A2K8TK98
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

53346:EM4838 RS15105
gene id: 53346:EM4838_RS15105
uniprot id: A0A1L8V2U9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

53346:EM4838 RS09435
gene id: 53346:EM4838_RS09435
uniprot id: A0A2K8TGD0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

53346:EM4838 RS05945
gene id: 53346:EM4838_RS05945
uniprot id: A0A1A6GBV9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

53346:EM4838 RS03450
gene id: 53346:EM4838_RS03450
uniprot id: A0A2K8TD38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

53346:EM4838 RS05955
gene id: 53346:EM4838_RS05955
uniprot id: A0A2K8TEE2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

53346:EM4838 RS12270
gene id: 53346:EM4838_RS12270
uniprot id: A0A1A6G5L0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

53346:EM4838 RS00335
gene id: 53346:EM4838_RS00335
uniprot id: A0A1L8V3N9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS14790
gene id: 53346:EM4838_RS14790
uniprot id: A0A1A6G9F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

53346:EM4838 RS14545
gene id: 53346:EM4838_RS14545
uniprot id: A0A1L8UNH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

53346:EM4838 RS01990
gene id: 53346:EM4838_RS01990
uniprot id: A0A1A6G908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS15460
gene id: 53346:EM4838_RS15460
uniprot id: A0A1A6G489
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

53346:EM4838 RS09005
gene id: 53346:EM4838_RS09005
uniprot id: A0A2K8TG24
names: Similarity
messages: Belongs to the XFP family.

53346:EM4838 RS00260
gene id: 53346:EM4838_RS00260
uniprot id: A0A242KVW3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

53346:EM4838 RS11815
gene id: 53346:EM4838_RS11815
uniprot id: A0A1L8ULZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

53346:EM4838 RS14465
gene id: 53346:EM4838_RS14465
uniprot id: A0A2K8TJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS13640
gene id: 53346:EM4838_RS13640
uniprot id: A0A1A6G6C4
names: Similarity
messages: Belongs to the WXG100 family.

53346:EM4838 RS11070
gene id: 53346:EM4838_RS11070
uniprot id: A0A2K8THA8
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

53346:EM4838 RS05005
gene id: 53346:EM4838_RS05005
uniprot id: A0A1A6G5T2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

53346:EM4838 RS00855
gene id: 53346:EM4838_RS00855
uniprot id: A0A2M9FRX2
names: Similarity
messages: Belongs to the aldose epimerase family.

53346:EM4838 RS01795
gene id: 53346:EM4838_RS01795
uniprot id: A0A2K8TCL1
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS01285
gene id: 53346:EM4838_RS01285
uniprot id: A0A1A6GAA0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12545
gene id: 53346:EM4838_RS12545
uniprot id: A0A1L8UNE4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

53346:EM4838 RS07330
gene id: 53346:EM4838_RS07330
uniprot id: A0A1L8UNQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

53346:EM4838 RS10640
gene id: 53346:EM4838_RS10640
uniprot id: A0A1A6GBT0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

53346:EM4838 RS03925
gene id: 53346:EM4838_RS03925
uniprot id: A0A2K8TDI7
names: Similarity
messages: Belongs to the UPF0213 family.

53346:EM4838 RS06340
gene id: 53346:EM4838_RS06340
uniprot id: A0A1L8UTB0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

53346:EM4838 RS12740
gene id: 53346:EM4838_RS12740
uniprot id: A0A1I4PND7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

53346:EM4838 RS17085
gene id: 53346:EM4838_RS17085
uniprot id: A0A2K8TFC5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

53346:EM4838 RS15330
gene id: 53346:EM4838_RS15330
uniprot id: A0A1I4L0L4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

53346:EM4838 RS14755
gene id: 53346:EM4838_RS14755
uniprot id: A0A1A6G7T3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

53346:EM4838 RS14495
gene id: 53346:EM4838_RS14495
uniprot id: A0A1L8UNI3
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS10110
gene id: 53346:EM4838_RS10110
uniprot id: A0A2K8TIJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

53346:EM4838 RS08810
gene id: 53346:EM4838_RS08810
uniprot id: A0A1L8UWZ8
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS16305
gene id: 53346:EM4838_RS16305
uniprot id: A0A2K8TK45
names: Similarity
messages: Belongs to the type IA topoisomerase family.

53346:EM4838 RS01815
gene id: 53346:EM4838_RS01815
uniprot id: A0A2K8TCA2
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS15060
gene id: 53346:EM4838_RS15060
uniprot id: A0A2K8TJ54
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

53346:EM4838 RS11080
gene id: 53346:EM4838_RS11080
uniprot id: A0A1L8UTG6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

53346:EM4838 RS05505
gene id: 53346:EM4838_RS05505
uniprot id: A0A2K8TG54
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

53346:EM4838 RS03840
gene id: 53346:EM4838_RS03840
uniprot id: A0A2K8TDE2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

53346:EM4838 RS11520
gene id: 53346:EM4838_RS11520
uniprot id: A0A1A6G3S1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

53346:EM4838 RS02620
gene id: 53346:EM4838_RS02620
uniprot id: A0A1L8UVQ3
names: Similarity
messages: Belongs to the asparaginase 1 family.

53346:EM4838 RS11425
gene id: 53346:EM4838_RS11425
uniprot id: A0A1L8UWB4
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09600
gene id: 53346:EM4838_RS09600
uniprot id: A0A1A6G774
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

53346:EM4838 RS10700
gene id: 53346:EM4838_RS10700
uniprot id: A0A1A6G6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

53346:EM4838 RS14470
gene id: 53346:EM4838_RS14470
uniprot id: A0A2K8TJ43
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

53346:EM4838 RS13705
gene id: 53346:EM4838_RS13705
uniprot id: A0A2K8TIF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

53346:EM4838 RS14415
gene id: 53346:EM4838_RS14415
uniprot id: A0A1I4P7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS13895
gene id: 53346:EM4838_RS13895
uniprot id: A0A1I4P0M5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

53346:EM4838 RS09130
gene id: 53346:EM4838_RS09130
uniprot id: A0A1L8UR08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

53346:EM4838 RS04380
gene id: 53346:EM4838_RS04380
uniprot id: A0A2K8TDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

53346:EM4838 RS13855
gene id: 53346:EM4838_RS13855
uniprot id: A0A1L8UQ39
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS01435
gene id: 53346:EM4838_RS01435
uniprot id: A0A2K8TC91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

53346:EM4838 RS14925
gene id: 53346:EM4838_RS14925
uniprot id: A0A2K8TJ20
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

53346:EM4838 RS12565
gene id: 53346:EM4838_RS12565
uniprot id: A0A2K8THX2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

53346:EM4838 RS15990
gene id: 53346:EM4838_RS15990
uniprot id: A0A2K8TJZ6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

53346:EM4838 RS12410
gene id: 53346:EM4838_RS12410
uniprot id: A0A1A6G5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

53346:EM4838 RS07395
gene id: 53346:EM4838_RS07395
uniprot id: A0A2K8TF64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

53346:EM4838 RS05500
gene id: 53346:EM4838_RS05500
uniprot id: A0A2K8TE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

53346:EM4838 RS04455
gene id: 53346:EM4838_RS04455
uniprot id: A0A1L8V4N9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

53346:EM4838 RS11790
gene id: 53346:EM4838_RS11790
uniprot id: A0A1A6GAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01750
gene id: 53346:EM4838_RS01750
uniprot id: A0A2K8TC94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

53346:EM4838 RS07315
gene id: 53346:EM4838_RS07315
uniprot id: A0A2K8TFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS01870
gene id: 53346:EM4838_RS01870
uniprot id: A0A2K8TCB2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

53346:EM4838 RS11960
gene id: 53346:EM4838_RS11960
uniprot id: A0A2M9FSR5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

53346:EM4838 RS07250
gene id: 53346:EM4838_RS07250
uniprot id: A0A2K8TF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS14705
gene id: 53346:EM4838_RS14705
uniprot id: A0A1A6G7U0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

53346:EM4838 RS00815
gene id: 53346:EM4838_RS00815
uniprot id: A0A2M9FRW8
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

53346:EM4838 RS03390
gene id: 53346:EM4838_RS03390
uniprot id: A0A2K8TD45
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

53346:EM4838 RS10095
gene id: 53346:EM4838_RS10095
uniprot id: A0A2K8TGT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

53346:EM4838 RS12990
gene id: 53346:EM4838_RS12990
uniprot id: A0A2K8TI43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS02605
gene id: 53346:EM4838_RS02605
uniprot id: A0A1A6GAG1
names: Similarity
messages: Belongs to the peptidase C1 family.

53346:EM4838 RS06355
gene id: 53346:EM4838_RS06355
uniprot id: A0A1A6G9M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

53346:EM4838 RS07110
gene id: 53346:EM4838_RS07110
uniprot id: A0A2K8TF71
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

53346:EM4838 RS01475
gene id: 53346:EM4838_RS01475
uniprot id: A0A2M9FNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

53346:EM4838 RS05490
gene id: 53346:EM4838_RS05490
uniprot id: A0A1L8UUB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

53346:EM4838 RS07810
gene id: 53346:EM4838_RS07810
uniprot id: A0A2K8TFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

53346:EM4838 RS00090
gene id: 53346:EM4838_RS00090
uniprot id: A0A1L8V2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

53346:EM4838 RS03855
gene id: 53346:EM4838_RS03855
uniprot id: A0A1A6G7U4
names: Similarity
messages: Belongs to the UPF0374 family.

53346:EM4838 RS09670
gene id: 53346:EM4838_RS09670
uniprot id: A0A1L8UXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

53346:EM4838 RS07745
gene id: 53346:EM4838_RS07745
uniprot id: A0A1L8V285
names: Similarity
messages: Belongs to the peptidase S49 family.

53346:EM4838 RS09660
gene id: 53346:EM4838_RS09660
uniprot id: A0A242L162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS09305
gene id: 53346:EM4838_RS09305
uniprot id: A0A2K8TG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

53346:EM4838 RS01915
gene id: 53346:EM4838_RS01915
uniprot id: A0A1A6GA22
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03345
gene id: 53346:EM4838_RS03345
uniprot id: A0A1L8V379
names: Similarity
messages: Belongs to the peptidase M24B family.

53346:EM4838 RS09665
gene id: 53346:EM4838_RS09665
uniprot id: A0A2K8TIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

53346:EM4838 RS11680
gene id: 53346:EM4838_RS11680
uniprot id: A0A2K8THG9
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS13955
gene id: 53346:EM4838_RS13955
uniprot id: A0A2K8TIJ9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

53346:EM4838 RS03735
gene id: 53346:EM4838_RS03735
uniprot id: A0A1A6G8D4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

53346:EM4838 RS16225
gene id: 53346:EM4838_RS16225
uniprot id: A0A2K8TK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

53346:EM4838 RS01930
gene id: 53346:EM4838_RS01930
uniprot id: A0A1A6GA19
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

53346:EM4838 RS05630
gene id: 53346:EM4838_RS05630
uniprot id: A0A1I4LK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

53346:EM4838 RS12925
gene id: 53346:EM4838_RS12925
uniprot id: A0A1L8UQH5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS02700
gene id: 53346:EM4838_RS02700
uniprot id: A0A1A6G8A5
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

53346:EM4838 RS12390
gene id: 53346:EM4838_RS12390
uniprot id: A0A242L310
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

53346:EM4838 RS01255
gene id: 53346:EM4838_RS01255
uniprot id: A0A2K8TC05
names: Similarity
messages: Belongs to the aldolase LacD family.

53346:EM4838 RS07635
gene id: 53346:EM4838_RS07635
uniprot id: A0A1L8V2H3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

53346:EM4838 RS02915
gene id: 53346:EM4838_RS02915
uniprot id: A0A1L8UVA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

53346:EM4838 RS09630
gene id: 53346:EM4838_RS09630
uniprot id: A0A2M9FQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

53346:EM4838 RS09495
gene id: 53346:EM4838_RS09495
uniprot id: A0A1L8UY49
names: Similarity
messages: Belongs to the phosphohexose mutase family.

53346:EM4838 RS14235
gene id: 53346:EM4838_RS14235
uniprot id: A0A1A6GDG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

53346:EM4838 RS05590
gene id: 53346:EM4838_RS05590
uniprot id: A0A1L8UUL2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

53346:EM4838 RS01275
gene id: 53346:EM4838_RS01275
uniprot id: A0A1A6G8L6
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS12685
gene id: 53346:EM4838_RS12685
uniprot id: A0A2K8TI00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

53346:EM4838 RS01540
gene id: 53346:EM4838_RS01540
uniprot id: A0A2K8TC98
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

53346:EM4838 RS14475
gene id: 53346:EM4838_RS14475
uniprot id: A0A1L8UN60
names: Similarity
messages: Belongs to the UPF0047 family.

53346:EM4838 RS05620
gene id: 53346:EM4838_RS05620
uniprot id: A0A1A6G4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

53346:EM4838 RS02645
gene id: 53346:EM4838_RS02645
uniprot id: A0A2K8TCN9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS13275
gene id: 53346:EM4838_RS13275
uniprot id: A0A1L8V0T5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

53346:EM4838 RS01045
gene id: 53346:EM4838_RS01045
uniprot id: A0A1L8V069
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

53346:EM4838 RS10535
gene id: 53346:EM4838_RS10535
uniprot id: A0A242L2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS05925
gene id: 53346:EM4838_RS05925
uniprot id: A0A1L8UMD6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

53346:EM4838 RS02740
gene id: 53346:EM4838_RS02740
uniprot id: A0A2K8TD27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

53346:EM4838 RS06755
gene id: 53346:EM4838_RS06755
uniprot id: A0A2K8TF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06800
gene id: 53346:EM4838_RS06800
uniprot id: A0A2K8TEU0
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

53346:EM4838 RS14745
gene id: 53346:EM4838_RS14745
uniprot id: A0A1A6G6T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

53346:EM4838 RS01040
gene id: 53346:EM4838_RS01040
uniprot id: A0A2M9FRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

53346:EM4838 RS01015
gene id: 53346:EM4838_RS01015
uniprot id: A0A2K8TDT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.
messages: Belongs to the peptidase C40 family.

53346:EM4838 RS05940
gene id: 53346:EM4838_RS05940
uniprot id: A0A1L8UMC5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

53346:EM4838 RS00670
gene id: 53346:EM4838_RS00670
uniprot id: A0A2K8TC22
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS02250
gene id: 53346:EM4838_RS02250
uniprot id: A0A1A6G9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS12310
gene id: 53346:EM4838_RS12310
uniprot id: A0A2K8THZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

53346:EM4838 RS06025
gene id: 53346:EM4838_RS06025
uniprot id: A0A1A6G973
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

53346:EM4838 RS09685
gene id: 53346:EM4838_RS09685
uniprot id: A0A1A6G856
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

53346:EM4838 RS14620
gene id: 53346:EM4838_RS14620
uniprot id: A0A1A6G858
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

53346:EM4838 RS05530
gene id: 53346:EM4838_RS05530
uniprot id: A0A2K8TE70
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

53346:EM4838 RS11420
gene id: 53346:EM4838_RS11420
uniprot id: A0A1L8UW70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

53346:EM4838 RS03370
gene id: 53346:EM4838_RS03370
uniprot id: A0A1L8V3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

53346:EM4838 RS02775
gene id: 53346:EM4838_RS02775
uniprot id: A0A2K8TCT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS01245
gene id: 53346:EM4838_RS01245
uniprot id: A0A2K8TDX0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

53346:EM4838 RS11095
gene id: 53346:EM4838_RS11095
uniprot id: A0A1L8UTP7
names: Subcellular Location Annotation
messages: Bacterial microcompartment

53346:EM4838 RS07830
gene id: 53346:EM4838_RS07830
uniprot id: A0A2K8TFL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

53346:EM4838 RS15510
gene id: 53346:EM4838_RS15510
uniprot id: A0A1L8V312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

53346:EM4838 RS04475
gene id: 53346:EM4838_RS04475
uniprot id: A0A1A6G515
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

53346:EM4838 RS10890
gene id: 53346:EM4838_RS10890
uniprot id: A0A1L8UTE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

53346:EM4838 RS12265
gene id: 53346:EM4838_RS12265
uniprot id: A0A1A6G873
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

53346:EM4838 RS02515
gene id: 53346:EM4838_RS02515
uniprot id: A0A2K8TLA7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

53346:EM4838 RS11865
gene id: 53346:EM4838_RS11865
uniprot id: A0A1L8V0X9
names: Similarity
messages: Belongs to the UPF0177 family.

53346:EM4838 RS11610
gene id: 53346:EM4838_RS11610
uniprot id: A0A2K8THF8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

53346:EM4838 RS08040
gene id: 53346:EM4838_RS08040
uniprot id: A0A1A6G9A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

53346:EM4838 RS12060
gene id: 53346:EM4838_RS12060
uniprot id: A0A2K8TJG7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12505
gene id: 53346:EM4838_RS12505
uniprot id: A0A2K8THW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS13685
gene id: 53346:EM4838_RS13685
uniprot id: A0A2K8TIR5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

53346:EM4838 RS07290
gene id: 53346:EM4838_RS07290
uniprot id: A0A242KZQ8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

53346:EM4838 RS02440
gene id: 53346:EM4838_RS02440
uniprot id: A0A2K8TCM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS06805
gene id: 53346:EM4838_RS06805
uniprot id: A0A2K8TF11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06260
gene id: 53346:EM4838_RS06260
uniprot id: A0A242KZ55
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS13695
gene id: 53346:EM4838_RS13695
uniprot id: A0A2K8TK89
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12035
gene id: 53346:EM4838_RS12035
uniprot id: A0A2K8THM3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

53346:EM4838 RS15575
gene id: 53346:EM4838_RS15575
uniprot id: A0A1I4L3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

53346:EM4838 RS05980
gene id: 53346:EM4838_RS05980
uniprot id: A0A1L8UMF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

53346:EM4838 RS09145
gene id: 53346:EM4838_RS09145
uniprot id: A0A2K8TGF4
names: Similarity
messages: Belongs to the ThiD family.

53346:EM4838 RS05120
gene id: 53346:EM4838_RS05120
uniprot id: A0A1L8V1V5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

53346:EM4838 RS06790
gene id: 53346:EM4838_RS06790
uniprot id: A0A2K8TEV8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

53346:EM4838 RS09820
gene id: 53346:EM4838_RS09820
uniprot id: A0A1L8UXR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

53346:EM4838 RS02200
gene id: 53346:EM4838_RS02200
uniprot id: A0A2K8TCL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS02400
gene id: 53346:EM4838_RS02400
uniprot id: A0A2K8TCK4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

53346:EM4838 RS04635
gene id: 53346:EM4838_RS04635
uniprot id: A0A1L8UK21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS00155
gene id: 53346:EM4838_RS00155
uniprot id: A0A2K8TBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

53346:EM4838 RS08215
gene id: 53346:EM4838_RS08215
uniprot id: A0A2K8THJ4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

53346:EM4838 RS04450
gene id: 53346:EM4838_RS04450
uniprot id: A0A1A6G510
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

53346:EM4838 RS15195
gene id: 53346:EM4838_RS15195
uniprot id: A0A2K8TJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

53346:EM4838 RS00765
gene id: 53346:EM4838_RS00765
uniprot id: A0A1A6GC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

53346:EM4838 RS07705
gene id: 53346:EM4838_RS07705
uniprot id: A0A2K8TFG7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

53346:EM4838 RS08150
gene id: 53346:EM4838_RS08150
uniprot id: A0A2K8TFR0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

53346:EM4838 RS07775
gene id: 53346:EM4838_RS07775
uniprot id: A0A2K8TFK2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

53346:EM4838 RS14820
gene id: 53346:EM4838_RS14820
uniprot id: A0A2K8TJ77
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS13205
gene id: 53346:EM4838_RS13205
uniprot id: A0A2K8TI67
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

53346:EM4838 RS11025
gene id: 53346:EM4838_RS11025
uniprot id: A0A2K8THF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08015
gene id: 53346:EM4838_RS08015
uniprot id: A0A1A6G9B0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

53346:EM4838 RS05740
gene id: 53346:EM4838_RS05740
uniprot id: A0A1A6G9S0
names: Similarity
messages: Belongs to the UPF0234 family.

53346:EM4838 RS03600
gene id: 53346:EM4838_RS03600
uniprot id: A0A1I4M1G8
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS15210
gene id: 53346:EM4838_RS15210
uniprot id: A0A1L8V2Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

53346:EM4838 RS09445
gene id: 53346:EM4838_RS09445
uniprot id: A0A1A6G8J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

53346:EM4838 RS01305
gene id: 53346:EM4838_RS01305
uniprot id: A0A2K8TC14
names: Similarity
messages: Belongs to the amidinotransferase family.

53346:EM4838 RS00975
gene id: 53346:EM4838_RS00975
uniprot id: A0A2K8TBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS08915
gene id: 53346:EM4838_RS08915
uniprot id: A0A2K8TG58
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

53346:EM4838 RS01875
gene id: 53346:EM4838_RS01875
uniprot id: A0A2K8TCA7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

53346:EM4838 RS03590
gene id: 53346:EM4838_RS03590
uniprot id: A0A1L8V490
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

53346:EM4838 RS03460
gene id: 53346:EM4838_RS03460
uniprot id: A0A1A6GA96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

53346:EM4838 RS02185
gene id: 53346:EM4838_RS02185
uniprot id: A0A1L8UZD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS03385
gene id: 53346:EM4838_RS03385
uniprot id: A0A1A6G581
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

53346:EM4838 RS05010
gene id: 53346:EM4838_RS05010
uniprot id: A0A1A6G8G1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

53346:EM4838 RS01450
gene id: 53346:EM4838_RS01450
uniprot id: A0A1L8UYR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

53346:EM4838 RS00635
gene id: 53346:EM4838_RS00635
uniprot id: A0A2K8TBP2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

53346:EM4838 RS08100
gene id: 53346:EM4838_RS08100
uniprot id: A0A1L8UM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

53346:EM4838 RS07390
gene id: 53346:EM4838_RS07390
uniprot id: A0A1A6GA92
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

53346:EM4838 RS03465
gene id: 53346:EM4838_RS03465
uniprot id: A0A1L8V3J7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

53346:EM4838 RS05250
gene id: 53346:EM4838_RS05250
uniprot id: A0A1L8V248
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

53346:EM4838 RS15465
gene id: 53346:EM4838_RS15465
uniprot id: A0A1A6G6T1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

53346:EM4838 RS09785
gene id: 53346:EM4838_RS09785
uniprot id: A0A1A6GAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

53346:EM4838 RS13970
gene id: 53346:EM4838_RS13970
uniprot id: A0A1L8UPY1
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS09485
gene id: 53346:EM4838_RS09485
uniprot id: A0A1L8UY27
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

53346:EM4838 RS14205
gene id: 53346:EM4838_RS14205
uniprot id: A0A2K8TIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

53346:EM4838 RS15360
gene id: 53346:EM4838_RS15360
uniprot id: A0A1A6G471
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

53346:EM4838 RS00360
gene id: 53346:EM4838_RS00360
uniprot id: A0A1L8V344
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

53346:EM4838 RS02150
gene id: 53346:EM4838_RS02150
uniprot id: A0A1L8UZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

53346:EM4838 RS14880
gene id: 53346:EM4838_RS14880
uniprot id: A0A1A6G6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06810
gene id: 53346:EM4838_RS06810
uniprot id: A0A2K8TF05
names: Similarity
messages: Belongs to the OsmC/Ohr family.

53346:EM4838 RS06165
gene id: 53346:EM4838_RS06165
uniprot id: A0A1L8UT39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

53346:EM4838 RS07230
gene id: 53346:EM4838_RS07230
uniprot id: A0A1A6G8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

53346:EM4838 RS00250
gene id: 53346:EM4838_RS00250
uniprot id: A0A242KXK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS10540
gene id: 53346:EM4838_RS10540
uniprot id: A0A2K8TH08
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS04995
gene id: 53346:EM4838_RS04995
uniprot id: A0A1L8V1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

53346:EM4838 RS10290
gene id: 53346:EM4838_RS10290
uniprot id: A0A1A6G4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

53346:EM4838 RS13290
gene id: 53346:EM4838_RS13290
uniprot id: A0A1A6G8G0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

53346:EM4838 RS16080
gene id: 53346:EM4838_RS16080
uniprot id: A0A1L8US21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

53346:EM4838 RS01995
gene id: 53346:EM4838_RS01995
uniprot id: A0A2K8TCF6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS12135
gene id: 53346:EM4838_RS12135
uniprot id: A0A2K8THP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS09480
gene id: 53346:EM4838_RS09480
uniprot id: A0A1A6GCJ1
names: Similarity
messages: Belongs to the Fur family.

53346:EM4838 RS01200
gene id: 53346:EM4838_RS01200
uniprot id: A0A2K8TBY4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

53346:EM4838 RS11380
gene id: 53346:EM4838_RS11380
uniprot id: A0A1L8UWK5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

53346:EM4838 RS11695
gene id: 53346:EM4838_RS11695
uniprot id: A0A1L8UMD5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

53346:EM4838 RS14525
gene id: 53346:EM4838_RS14525
uniprot id: A0A2K8TLK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

53346:EM4838 RS05720
gene id: 53346:EM4838_RS05720
uniprot id: A0A1L8UU66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS02435
gene id: 53346:EM4838_RS02435
uniprot id: A0A2K8TCX6
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS11540
gene id: 53346:EM4838_RS11540
uniprot id: A0A2K8THK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

53346:EM4838 RS03000
gene id: 53346:EM4838_RS03000
uniprot id: A0A1A6G5B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

53346:EM4838 RS05435
gene id: 53346:EM4838_RS05435
uniprot id: A0A1L8UUD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

53346:EM4838 RS09420
gene id: 53346:EM4838_RS09420
uniprot id: A0A1A6G8K4
names: Similarity
messages: Belongs to the acylphosphatase family.

53346:EM4838 RS14865
gene id: 53346:EM4838_RS14865
uniprot id: A0A2K8TJ18
names: Similarity
messages: Belongs to the ABC transporter superfamily.

53346:EM4838 RS05185
gene id: 53346:EM4838_RS05185
uniprot id: A0A1I4LQ37
names: Similarity
messages: Belongs to the DprA/Smf family.

53346:EM4838 RS10200
gene id: 53346:EM4838_RS10200
uniprot id: A0A1L8USZ6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

53346:EM4838 RS04005
gene id: 53346:EM4838_RS04005
uniprot id: A0A2K8TDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS03900
gene id: 53346:EM4838_RS03900
uniprot id: A0A1A6G7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

53346:EM4838 RS03790
gene id: 53346:EM4838_RS03790
uniprot id: A0A1A6G8P8
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS12045
gene id: 53346:EM4838_RS12045
uniprot id: A0A2K8THU5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS00055
gene id: 53346:EM4838_RS00055
uniprot id: A0A2K8TJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

53346:EM4838 RS15170
gene id: 53346:EM4838_RS15170
uniprot id: A0A1L8V2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

53346:EM4838 RS08030
gene id: 53346:EM4838_RS08030
uniprot id: A0A1A6GAK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

53346:EM4838 RS08695
gene id: 53346:EM4838_RS08695
uniprot id: A0A1A6G9S5
names: Subcellular Location Annotation
messages: Cytoplasm

53346:EM4838 RS05455
gene id: 53346:EM4838_RS05455
uniprot id: A0A1I4LLD2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

53346:EM4838 RS09805
gene id: 53346:EM4838_RS09805
uniprot id: A0A1A6GBF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

53346:EM4838 RS08780
gene id: 53346:EM4838_RS08780
uniprot id: A0A242L1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

53346:EM4838 RS07335
gene id: 53346:EM4838_RS07335
uniprot id: A0A1L8UNU0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

53346:EM4838 RS09775
gene id: 53346:EM4838_RS09775
uniprot id: A0A1A6GBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

53346:EM4838 RS01690
gene id: 53346:EM4838_RS01690
uniprot id: A0A2K8TC85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

53346:EM4838 RS09540
gene id: 53346:EM4838_RS09540
uniprot id: A0A1A6G757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06405
gene id: 53346:EM4838_RS06405
uniprot id: A0A1A6G9N7
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS06220
gene id: 53346:EM4838_RS06220
uniprot id: A0A2K8TGH9
names: Similarity
messages: Belongs to the acetyltransferase family.

53346:EM4838 RS15300
gene id: 53346:EM4838_RS15300
uniprot id: A0A1I4L0I5
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS03375
gene id: 53346:EM4838_RS03375
uniprot id: A0A2K8TD40
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

53346:EM4838 RS02415
gene id: 53346:EM4838_RS02415
uniprot id: A0A2K8TCQ0
names: Subcellular Location Annotation
messages: Membrane

53346:EM4838 RS07200
gene id: 53346:EM4838_RS07200
uniprot id: A0A2K8TF38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

53346:EM4838 RS07800
gene id: 53346:EM4838_RS07800
uniprot id: A0A1A6G3Y5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

53346:EM4838 RS11180
gene id: 53346:EM4838_RS11180
uniprot id: A0A242L257
names: Similarity
messages: Belongs to the phosphohexose mutase family.

53346:EM4838 RS11435
gene id: 53346:EM4838_RS11435
uniprot id: A0A2K8THM9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

53346:EM4838 RS11545
gene id: 53346:EM4838_RS11545
uniprot id: A0A242L2B5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

53346:EM4838 RS01125
gene id: 53346:EM4838_RS01125
uniprot id: A0A1A6GAC9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

53346:EM4838 RS08275
gene id: 53346:EM4838_RS08275
uniprot id: A0A2K8TFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

53346:EM4838 RS05445
gene id: 53346:EM4838_RS05445
uniprot id: A0A1I4LLK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

53346:EM4838 RS06330
gene id: 53346:EM4838_RS06330
uniprot id: A0A1L8UT69
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

53346:EM4838 RS12885
gene id: 53346:EM4838_RS12885
uniprot id: A0A1L8UQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

53346:EM4838 RS06170
gene id: 53346:EM4838_RS06170
uniprot id: A0A1A6G9I9
names: Similarity
messages: Belongs to the UPF0398 family.

53346:EM4838 RS12020
gene id: 53346:EM4838_RS12020
uniprot id: A0A1L8V0S7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

53346:EM4838 RS07970
gene id: 53346:EM4838_RS07970
uniprot id: A0A2K8TFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

53346:EM4838 RS15715
gene id: 53346:EM4838_RS15715
uniprot id: A0A2K8TKB3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

53346:EM4838 RS14135
gene id: 53346:EM4838_RS14135
uniprot id: A0A1I4PAW1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS14535
gene id: 53346:EM4838_RS14535
uniprot id: A0A1I4MGU1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

53346:EM4838 RS13940
gene id: 53346:EM4838_RS13940
uniprot id: A0A2K8TIK0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

53346:EM4838 RS14050
gene id: 53346:EM4838_RS14050
uniprot id: A0A2K8TIL8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

53346:EM4838 RS13410
gene id: 53346:EM4838_RS13410
uniprot id: A0A2K8TIA6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

53346:EM4838 RS07835
gene id: 53346:EM4838_RS07835
uniprot id: A0A2K8TFK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

53346:EM4838 RS04730
gene id: 53346:EM4838_RS04730
uniprot id: A0A1L8V1A7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

53346:EM4838 RS12785
gene id: 53346:EM4838_RS12785
uniprot id: A0A1L8UQA8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

53346:EM4838 RS11590
gene id: 53346:EM4838_RS11590
uniprot id: A0A1L8UW75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

53346:EM4838 RS14010
gene id: 53346:EM4838_RS14010
uniprot id: A0A2K8TIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

53346:EM4838 RS06420
gene id: 53346:EM4838_RS06420
uniprot id: A0A2K8TET6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

53346:EM4838 RS02760
gene id: 53346:EM4838_RS02760
uniprot id: A0A1L8UVE0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

53346:EM4838 RS09010
gene id: 53346:EM4838_RS09010
uniprot id: A0A2K8TG50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

53346:EM4838 RS09560
gene id: 53346:EM4838_RS09560
uniprot id: A0A1A6G878
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.