526227:MESIL RS09115
gene id: 526227:MESIL_RS09115
uniprot id: D7BFY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

526227:MESIL RS03845
gene id: 526227:MESIL_RS03845
uniprot id: D7BBA7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526227:MESIL RS16510
gene id: 526227:MESIL_RS16510
uniprot id: D7BIT8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

526227:MESIL RS18045
gene id: 526227:MESIL_RS18045
uniprot id: D7BJM8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

526227:MESIL RS01445
gene id: 526227:MESIL_RS01445
uniprot id: D7BHJ3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

526227:MESIL RS01865
gene id: 526227:MESIL_RS01865
uniprot id: D7BI34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

526227:MESIL RS15075
gene id: 526227:MESIL_RS15075
uniprot id: D7BDL4
names: Similarity
messages: Belongs to the asp23 family.

526227:MESIL RS00325
gene id: 526227:MESIL_RS00325
uniprot id: D7BG90
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

526227:MESIL RS06860
gene id: 526227:MESIL_RS06860
uniprot id: D7BEL3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

526227:MESIL RS10610
gene id: 526227:MESIL_RS10610
uniprot id: D7BHP2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

526227:MESIL RS14705
gene id: 526227:MESIL_RS14705
uniprot id: D7BDE3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS14540
gene id: 526227:MESIL_RS14540
uniprot id: D7BCZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

526227:MESIL RS03745
gene id: 526227:MESIL_RS03745
uniprot id: D7BB88
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526227:MESIL RS10825
gene id: 526227:MESIL_RS10825
uniprot id: D7BHT3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

526227:MESIL RS09375
gene id: 526227:MESIL_RS09375
uniprot id: D7BGC3
names: Similarity
messages: Belongs to the Skp family.

526227:MESIL RS09340
gene id: 526227:MESIL_RS09340
uniprot id: D7BGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

526227:MESIL RS05390
gene id: 526227:MESIL_RS05390
uniprot id: D7BD51
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

526227:MESIL RS08355
gene id: 526227:MESIL_RS08355
uniprot id: D7BFJ1
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

526227:MESIL RS11460
gene id: 526227:MESIL_RS11460
uniprot id: D7BIG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

526227:MESIL RS06305
gene id: 526227:MESIL_RS06305
uniprot id: D7BDZ4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

526227:MESIL RS03140
gene id: 526227:MESIL_RS03140
uniprot id: D7BAM5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526227:MESIL RS04840
gene id: 526227:MESIL_RS04840
uniprot id: D7BCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS13590
gene id: 526227:MESIL_RS13590
uniprot id: D7BC55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS06070
gene id: 526227:MESIL_RS06070
uniprot id: D7BDA3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

526227:MESIL RS00685
gene id: 526227:MESIL_RS00685
uniprot id: D7BGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526227:MESIL RS15550
gene id: 526227:MESIL_RS15550
uniprot id: D7BE65
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

526227:MESIL RS05350
gene id: 526227:MESIL_RS05350
uniprot id: D7BD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526227:MESIL RS11355
gene id: 526227:MESIL_RS11355
uniprot id: D7BIE9
names: Similarity
messages: Belongs to the acylphosphatase family.

526227:MESIL RS03960
gene id: 526227:MESIL_RS03960
uniprot id: D7BBD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526227:MESIL RS17345
gene id: 526227:MESIL_RS17345
uniprot id: D7BJA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

526227:MESIL RS14565
gene id: 526227:MESIL_RS14565
uniprot id: D7BD04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS03535
gene id: 526227:MESIL_RS03535
uniprot id: D7BB51
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

526227:MESIL RS12300
gene id: 526227:MESIL_RS12300
uniprot id: D7BAS9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12650
gene id: 526227:MESIL_RS12650
uniprot id: D7BB00
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526227:MESIL RS10820
gene id: 526227:MESIL_RS10820
uniprot id: D7BHT2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

526227:MESIL RS11945
gene id: 526227:MESIL_RS11945
uniprot id: D7BAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS11670
gene id: 526227:MESIL_RS11670
uniprot id: D7BIK5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526227:MESIL RS07650
gene id: 526227:MESIL_RS07650
uniprot id: D7BF59
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

526227:MESIL RS01765
gene id: 526227:MESIL_RS01765
uniprot id: D7BI14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

526227:MESIL RS06630
gene id: 526227:MESIL_RS06630
uniprot id: D7BEG8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

526227:MESIL RS12305
gene id: 526227:MESIL_RS12305
uniprot id: D7BAT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS01470
gene id: 526227:MESIL_RS01470
uniprot id: D7BHJ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526227:MESIL RS05885
gene id: 526227:MESIL_RS05885
uniprot id: D7BDR1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

526227:MESIL RS12635
gene id: 526227:MESIL_RS12635
uniprot id: D7BAZ7
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS07885
gene id: 526227:MESIL_RS07885
uniprot id: D7BFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

526227:MESIL RS14160
gene id: 526227:MESIL_RS14160
uniprot id: D7BCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

526227:MESIL RS14485
gene id: 526227:MESIL_RS14485
uniprot id: D7BCY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

526227:MESIL RS15230
gene id: 526227:MESIL_RS15230
uniprot id: D7BDP4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

526227:MESIL RS04655
gene id: 526227:MESIL_RS04655
uniprot id: D7BCE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

526227:MESIL RS11510
gene id: 526227:MESIL_RS11510
uniprot id: D7BIH7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

526227:MESIL RS06845
gene id: 526227:MESIL_RS06845
uniprot id: D7BEL0
names: Similarity
messages: Belongs to the threonine synthase family.

526227:MESIL RS12835
gene id: 526227:MESIL_RS12835
uniprot id: D7BB35
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

526227:MESIL RS07400
gene id: 526227:MESIL_RS07400
uniprot id: D7BF09
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526227:MESIL RS06460
gene id: 526227:MESIL_RS06460
uniprot id: D7BED3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526227:MESIL RS17065
gene id: 526227:MESIL_RS17065
uniprot id: D7BJ50
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

526227:MESIL RS02210
gene id: 526227:MESIL_RS02210
uniprot id: D7BI99
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

526227:MESIL RS14605
gene id: 526227:MESIL_RS14605
uniprot id: D7BD12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

526227:MESIL RS00395
gene id: 526227:MESIL_RS00395
uniprot id: D7BGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS03395
gene id: 526227:MESIL_RS03395
uniprot id: D7BAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS03645
gene id: 526227:MESIL_RS03645
uniprot id: D7BB69
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

526227:MESIL RS06265
gene id: 526227:MESIL_RS06265
uniprot id: D7BDY6
names: Similarity
messages: Belongs to the TrpF family.

526227:MESIL RS10745
gene id: 526227:MESIL_RS10745
uniprot id: D7BHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS02830
gene id: 526227:MESIL_RS02830
uniprot id: D7BAH0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

526227:MESIL RS02255
gene id: 526227:MESIL_RS02255
uniprot id: D7B9U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526227:MESIL RS02850
gene id: 526227:MESIL_RS02850
uniprot id: D7BAH4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

526227:MESIL RS10060
gene id: 526227:MESIL_RS10060
uniprot id: D7BH20
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

526227:MESIL RS17265
gene id: 526227:MESIL_RS17265
uniprot id: D7BIM9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS17625
gene id: 526227:MESIL_RS17625
uniprot id: D7BJF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

526227:MESIL RS12870
gene id: 526227:MESIL_RS12870
uniprot id: D7BBF4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

526227:MESIL RS13790
gene id: 526227:MESIL_RS13790
uniprot id: D7BC93
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

526227:MESIL RS04215
gene id: 526227:MESIL_RS04215
uniprot id: D7BBU4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

526227:MESIL RS03090
gene id: 526227:MESIL_RS03090
uniprot id: D7BAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

526227:MESIL RS11775
gene id: 526227:MESIL_RS11775
uniprot id: D7BA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS07640
gene id: 526227:MESIL_RS07640
uniprot id: D7BF57
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

526227:MESIL RS17620
gene id: 526227:MESIL_RS17620
uniprot id: D7BJF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

526227:MESIL RS08235
gene id: 526227:MESIL_RS08235
uniprot id: D7BFG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS13115
gene id: 526227:MESIL_RS13115
uniprot id: D7BBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

526227:MESIL RS12510
gene id: 526227:MESIL_RS12510
uniprot id: D7BAX2
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS08065
gene id: 526227:MESIL_RS08065
uniprot id: D7BFD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526227:MESIL RS12045
gene id: 526227:MESIL_RS12045
uniprot id: D7BAC0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

526227:MESIL RS10845
gene id: 526227:MESIL_RS10845
uniprot id: D7BHT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS03530
gene id: 526227:MESIL_RS03530
uniprot id: D7BB50
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

526227:MESIL RS13860
gene id: 526227:MESIL_RS13860
uniprot id: D7BCA5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

526227:MESIL RS08295
gene id: 526227:MESIL_RS08295
uniprot id: D7BFH9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

526227:MESIL RS17630
gene id: 526227:MESIL_RS17630
uniprot id: D7BJF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

526227:MESIL RS12535
gene id: 526227:MESIL_RS12535
uniprot id: D7BAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

526227:MESIL RS14195
gene id: 526227:MESIL_RS14195
uniprot id: D7BCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

526227:MESIL RS16275
gene id: 526227:MESIL_RS16275
uniprot id: D7BIP4
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

526227:MESIL RS07770
gene id: 526227:MESIL_RS07770
uniprot id: D7BF82
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS04965
gene id: 526227:MESIL_RS04965
uniprot id: D7BCK5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS11320
gene id: 526227:MESIL_RS11320
uniprot id: D7BIE3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS01115
gene id: 526227:MESIL_RS01115
uniprot id: D7BHC4
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS16795
gene id: 526227:MESIL_RS16795
uniprot id: D7BIZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

526227:MESIL RS15360
gene id: 526227:MESIL_RS15360
uniprot id: D7BE30
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

526227:MESIL RS17190
gene id: 526227:MESIL_RS17190
uniprot id: D7BIP3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

526227:MESIL RS15125
gene id: 526227:MESIL_RS15125
uniprot id: D7BDM4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526227:MESIL RS08965
gene id: 526227:MESIL_RS08965
uniprot id: D7BFV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

526227:MESIL RS04370
gene id: 526227:MESIL_RS04370
uniprot id: D7BBX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

526227:MESIL RS06685
gene id: 526227:MESIL_RS06685
uniprot id: D7BEH8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS06980
gene id: 526227:MESIL_RS06980
uniprot id: D7BES6
names: Similarity
messages: Belongs to the DNA photolyase family.

526227:MESIL RS01790
gene id: 526227:MESIL_RS01790
uniprot id: D7BI19
names: Similarity
messages: Belongs to the Fur family.

526227:MESIL RS01870
gene id: 526227:MESIL_RS01870
uniprot id: D7BI35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

526227:MESIL RS12275
gene id: 526227:MESIL_RS12275
uniprot id: D7BAG3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS11275
gene id: 526227:MESIL_RS11275
uniprot id: D7BID4
names: Similarity
messages: Belongs to the GreA/GreB family.

526227:MESIL RS12240
gene id: 526227:MESIL_RS12240
uniprot id: D7BAF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

526227:MESIL RS17055
gene id: 526227:MESIL_RS17055
uniprot id: D7BJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS09380
gene id: 526227:MESIL_RS09380
uniprot id: D7BGC4
names: Similarity
messages: Belongs to the Skp family.

526227:MESIL RS03235
gene id: 526227:MESIL_RS03235
uniprot id: D7BAN4
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12130
gene id: 526227:MESIL_RS12130
uniprot id: D7BAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS12950
gene id: 526227:MESIL_RS12950
uniprot id: D7BBG9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS05645
gene id: 526227:MESIL_RS05645
uniprot id: D7BDA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

526227:MESIL RS09415
gene id: 526227:MESIL_RS09415
uniprot id: D7BGD0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS10230
gene id: 526227:MESIL_RS10230
uniprot id: D7BH52
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

526227:MESIL RS06670
gene id: 526227:MESIL_RS06670
uniprot id: D7BEH5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

526227:MESIL RS12355
gene id: 526227:MESIL_RS12355
uniprot id: D7BAU0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

526227:MESIL RS03270
gene id: 526227:MESIL_RS03270
uniprot id: D7BAP0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526227:MESIL RS10195
gene id: 526227:MESIL_RS10195
uniprot id: D7BH45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

526227:MESIL RS11835
gene id: 526227:MESIL_RS11835
uniprot id: D7BA79
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

526227:MESIL RS15410
gene id: 526227:MESIL_RS15410
uniprot id: D7BE40
names: Similarity
messages: Belongs to the glutamine synthetase family.

526227:MESIL RS06680
gene id: 526227:MESIL_RS06680
uniprot id: D7BEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

526227:MESIL RS04100
gene id: 526227:MESIL_RS04100
uniprot id: D7BBS2
names: Similarity
messages: Belongs to the peptidase S16 family.

526227:MESIL RS10205
gene id: 526227:MESIL_RS10205
uniprot id: D7BH47
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

526227:MESIL RS06945
gene id: 526227:MESIL_RS06945
uniprot id: D7BEM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

526227:MESIL RS14520
gene id: 526227:MESIL_RS14520
uniprot id: D7BCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

526227:MESIL RS01330
gene id: 526227:MESIL_RS01330
uniprot id: D7BHG9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

526227:MESIL RS07705
gene id: 526227:MESIL_RS07705
uniprot id: D7BF69
names: Similarity
messages: Belongs to the GARS family.

526227:MESIL RS09965
gene id: 526227:MESIL_RS09965
uniprot id: D7BH03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

526227:MESIL RS03295
gene id: 526227:MESIL_RS03295
uniprot id: D7BAP5
names: Similarity
messages: Belongs to the PstS family.

526227:MESIL RS18025
gene id: 526227:MESIL_RS18025
uniprot id: D7BJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

526227:MESIL RS11115
gene id: 526227:MESIL_RS11115
uniprot id: D7BHY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

526227:MESIL RS15265
gene id: 526227:MESIL_RS15265
uniprot id: D7BDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

526227:MESIL RS00820
gene id: 526227:MESIL_RS00820
uniprot id: D7BGV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

526227:MESIL RS15880
gene id: 526227:MESIL_RS15880
uniprot id: D7BEN6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

526227:MESIL RS01410
gene id: 526227:MESIL_RS01410
uniprot id: D7BHI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

526227:MESIL RS12825
gene id: 526227:MESIL_RS12825
uniprot id: D7BB33
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

526227:MESIL RS16400
gene id: 526227:MESIL_RS16400
uniprot id: D7BIR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526227:MESIL RS09420
gene id: 526227:MESIL_RS09420
uniprot id: D7BGD1
names: Similarity
messages: Belongs to the hemerythrin family.

526227:MESIL RS16280
gene id: 526227:MESIL_RS16280
uniprot id: D7BIP5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

526227:MESIL RS03425
gene id: 526227:MESIL_RS03425
uniprot id: D7BAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS13470
gene id: 526227:MESIL_RS13470
uniprot id: D7BC35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

526227:MESIL RS01990
gene id: 526227:MESIL_RS01990
uniprot id: D7BI56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

526227:MESIL RS07240
gene id: 526227:MESIL_RS07240
uniprot id: D7BEX7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

526227:MESIL RS16695
gene id: 526227:MESIL_RS16695
uniprot id: D7BIX6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

526227:MESIL RS13160
gene id: 526227:MESIL_RS13160
uniprot id: D7BBL0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

526227:MESIL RS10600
gene id: 526227:MESIL_RS10600
uniprot id: D7BHP0
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

526227:MESIL RS14635
gene id: 526227:MESIL_RS14635
uniprot id: D7BD18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

526227:MESIL RS11635
gene id: 526227:MESIL_RS11635
uniprot id: D7BIJ8
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

526227:MESIL RS15090
gene id: 526227:MESIL_RS15090
uniprot id: D7BDL7
names: Similarity
messages: Belongs to the UPF0166 family.

526227:MESIL RS05685
gene id: 526227:MESIL_RS05685
uniprot id: D7BDB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

526227:MESIL RS16430
gene id: 526227:MESIL_RS16430
uniprot id: D7BIS3
names: Similarity
messages: Belongs to the transketolase family.

526227:MESIL RS11900
gene id: 526227:MESIL_RS11900
uniprot id: D7BA91
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

526227:MESIL RS00800
gene id: 526227:MESIL_RS00800
uniprot id: D7BGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS10215
gene id: 526227:MESIL_RS10215
uniprot id: D7BH49
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

526227:MESIL RS15870
gene id: 526227:MESIL_RS15870
uniprot id: D7BEC2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526227:MESIL RS05335
gene id: 526227:MESIL_RS05335
uniprot id: D7BD40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526227:MESIL RS05605
gene id: 526227:MESIL_RS05605
uniprot id: D7BD94
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

526227:MESIL RS09485
gene id: 526227:MESIL_RS09485
uniprot id: D7BGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS05385
gene id: 526227:MESIL_RS05385
uniprot id: D7BD50
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

526227:MESIL RS12125
gene id: 526227:MESIL_RS12125
uniprot id: D7BAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS08090
gene id: 526227:MESIL_RS08090
uniprot id: D7BFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS18175
gene id: 526227:MESIL_RS18175
uniprot id: D7BJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

526227:MESIL RS00275
gene id: 526227:MESIL_RS00275
uniprot id: D7BG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS13870
gene id: 526227:MESIL_RS13870
uniprot id: D7BCA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

526227:MESIL RS05840
gene id: 526227:MESIL_RS05840
uniprot id: D7BDQ5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

526227:MESIL RS16945
gene id: 526227:MESIL_RS16945
uniprot id: D7BJ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

526227:MESIL RS04675
gene id: 526227:MESIL_RS04675
uniprot id: D7BCE8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS02300
gene id: 526227:MESIL_RS02300
uniprot id: D7B9V7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

526227:MESIL RS18000
gene id: 526227:MESIL_RS18000
uniprot id: D7BJL9
names: Similarity
messages: Belongs to the GSP E family.

526227:MESIL RS11450
gene id: 526227:MESIL_RS11450
uniprot id: D7BIG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

526227:MESIL RS15060
gene id: 526227:MESIL_RS15060
uniprot id: D7BDL1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS05050
gene id: 526227:MESIL_RS05050
uniprot id: D7BCM0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

526227:MESIL RS15535
gene id: 526227:MESIL_RS15535
uniprot id: D7BE62
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS18040
gene id: 526227:MESIL_RS18040
uniprot id: D7BJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

526227:MESIL RS05470
gene id: 526227:MESIL_RS05470
uniprot id: D7BD68
names: Similarity
messages: Belongs to the FUN14 family.

526227:MESIL RS09780
gene id: 526227:MESIL_RS09780
uniprot id: D7BGK5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

526227:MESIL RS16085
gene id: 526227:MESIL_RS16085
uniprot id: D7BES2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

526227:MESIL RS12715
gene id: 526227:MESIL_RS12715
uniprot id: D7BB11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

526227:MESIL RS16365
gene id: 526227:MESIL_RS16365
uniprot id: D7BIR0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

526227:MESIL RS01770
gene id: 526227:MESIL_RS01770
uniprot id: D7BI15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS08285
gene id: 526227:MESIL_RS08285
uniprot id: D7BFH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

526227:MESIL RS07325
gene id: 526227:MESIL_RS07325
uniprot id: D7BEZ4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

526227:MESIL RS04815
gene id: 526227:MESIL_RS04815
uniprot id: D7BCH6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-65 and Arg-68) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

526227:MESIL RS04750
gene id: 526227:MESIL_RS04750
uniprot id: D7BCG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

526227:MESIL RS06450
gene id: 526227:MESIL_RS06450
uniprot id: D7BED1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

526227:MESIL RS06650
gene id: 526227:MESIL_RS06650
uniprot id: D7BEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

526227:MESIL RS00930
gene id: 526227:MESIL_RS00930
uniprot id: D7BGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS01830
gene id: 526227:MESIL_RS01830
uniprot id: D7BI27
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS00940
gene id: 526227:MESIL_RS00940
uniprot id: D7BGX5
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS16500
gene id: 526227:MESIL_RS16500
uniprot id: D7BIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS16740
gene id: 526227:MESIL_RS16740
uniprot id: D7BIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS15080
gene id: 526227:MESIL_RS15080
uniprot id: D7BDL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

526227:MESIL RS17260
gene id: 526227:MESIL_RS17260
uniprot id: D7BIN0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS06340
gene id: 526227:MESIL_RS06340
uniprot id: D7BE02
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

526227:MESIL RS05915
gene id: 526227:MESIL_RS05915
uniprot id: D7BDR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

526227:MESIL RS03905
gene id: 526227:MESIL_RS03905
uniprot id: D7BBB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

526227:MESIL RS07510
gene id: 526227:MESIL_RS07510
uniprot id: D7BF32
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

526227:MESIL RS18320
gene id: 526227:MESIL_RS18320
uniprot id: D7BJT0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

526227:MESIL RS08610
gene id: 526227:MESIL_RS08610
uniprot id: D7BFP1
names: Similarity
messages: Belongs to the aspartokinase family.

526227:MESIL RS04310
gene id: 526227:MESIL_RS04310
uniprot id: D7BBW3
names: Similarity
messages: Belongs to the Fur family.

526227:MESIL RS11980
gene id: 526227:MESIL_RS11980
uniprot id: D7BAA7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

526227:MESIL RS00350
gene id: 526227:MESIL_RS00350
uniprot id: D7BG95
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

526227:MESIL RS01680
gene id: 526227:MESIL_RS01680
uniprot id: D7BHZ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

526227:MESIL RS18630
gene id: 526227:MESIL_RS18630
uniprot id: D7BA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Cell outer membrane
messages: Membrane
messages: Periplasm

526227:MESIL RS12630
gene id: 526227:MESIL_RS12630
uniprot id: D7BAZ6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

526227:MESIL RS10415
gene id: 526227:MESIL_RS10415
uniprot id: D7BH90
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526227:MESIL RS14585
gene id: 526227:MESIL_RS14585
uniprot id: D7BD08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS07715
gene id: 526227:MESIL_RS07715
uniprot id: D7BF71
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

526227:MESIL RS03755
gene id: 526227:MESIL_RS03755
uniprot id: D7BB90
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

526227:MESIL RS08430
gene id: 526227:MESIL_RS08430
uniprot id: D7BFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

526227:MESIL RS09960
gene id: 526227:MESIL_RS09960
uniprot id: D7BH02
names: Similarity
messages: Belongs to the cytochrome c-552 family.

526227:MESIL RS00890
gene id: 526227:MESIL_RS00890
uniprot id: D7BGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS16600
gene id: 526227:MESIL_RS16600
uniprot id: D7BIV6
names: Similarity
messages: Belongs to the glutamine synthetase family.

526227:MESIL RS10080
gene id: 526227:MESIL_RS10080
uniprot id: D7BH24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

526227:MESIL RS09455
gene id: 526227:MESIL_RS09455
uniprot id: D7BGD8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

526227:MESIL RS10930
gene id: 526227:MESIL_RS10930
uniprot id: D7BHV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS18405
gene id: 526227:MESIL_RS18405
uniprot id: D7BJU7
names: Similarity
messages: Belongs to the ParB family.

526227:MESIL RS15615
gene id: 526227:MESIL_RS15615
uniprot id: D7BE75
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS17785
gene id: 526227:MESIL_RS17785
uniprot id: D7BAH0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

526227:MESIL RS03005
gene id: 526227:MESIL_RS03005
uniprot id: D7BAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

526227:MESIL RS14560
gene id: 526227:MESIL_RS14560
uniprot id: D7BD03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

526227:MESIL RS05960
gene id: 526227:MESIL_RS05960
uniprot id: D7BDS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

526227:MESIL RS08350
gene id: 526227:MESIL_RS08350
uniprot id: D7BFJ0
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

526227:MESIL RS10875
gene id: 526227:MESIL_RS10875
uniprot id: D7BHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

526227:MESIL RS06890
gene id: 526227:MESIL_RS06890
uniprot id: D7BEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS15170
gene id: 526227:MESIL_RS15170
uniprot id: D7BDN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

526227:MESIL RS10200
gene id: 526227:MESIL_RS10200
uniprot id: D7BH46
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

526227:MESIL RS02220
gene id: 526227:MESIL_RS02220
uniprot id: D7BIA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS10305
gene id: 526227:MESIL_RS10305
uniprot id: D7BH67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

526227:MESIL RS15440
gene id: 526227:MESIL_RS15440
uniprot id: D7BE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS12665
gene id: 526227:MESIL_RS12665
uniprot id: D7BB03
names: Similarity
messages: Belongs to the peptidase U62 family.

526227:MESIL RS05845
gene id: 526227:MESIL_RS05845
uniprot id: D7BDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

526227:MESIL RS05085
gene id: 526227:MESIL_RS05085
uniprot id: D7BCM7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

526227:MESIL RS08410
gene id: 526227:MESIL_RS08410
uniprot id: D7BFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

526227:MESIL RS09880
gene id: 526227:MESIL_RS09880
uniprot id: D7BGM5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

526227:MESIL RS06950
gene id: 526227:MESIL_RS06950
uniprot id: D7BEN0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS03150
gene id: 526227:MESIL_RS03150
uniprot id: D7BAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

526227:MESIL RS13400
gene id: 526227:MESIL_RS13400
uniprot id: D7BBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

526227:MESIL RS03145
gene id: 526227:MESIL_RS03145
uniprot id: D7BAM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

526227:MESIL RS00200
gene id: 526227:MESIL_RS00200
uniprot id: D7BG65
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS00220
gene id: 526227:MESIL_RS00220
uniprot id: D7BG69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

526227:MESIL RS15155
gene id: 526227:MESIL_RS15155
uniprot id: D7BDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

526227:MESIL RS05740
gene id: 526227:MESIL_RS05740
uniprot id: D7BDC0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

526227:MESIL RS11985
gene id: 526227:MESIL_RS11985
uniprot id: D7BAA8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS03865
gene id: 526227:MESIL_RS03865
uniprot id: D7BBB1
names: Similarity
messages: Belongs to the GSP E family.

526227:MESIL RS13325
gene id: 526227:MESIL_RS13325
uniprot id: D7BBP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

526227:MESIL RS01975
gene id: 526227:MESIL_RS01975
uniprot id: D7BI53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

526227:MESIL RS15540
gene id: 526227:MESIL_RS15540
uniprot id: D7BE63
names: Similarity
messages: Belongs to the peptidase S58 family.

526227:MESIL RS07805
gene id: 526227:MESIL_RS07805
uniprot id: D7BF90
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

526227:MESIL RS02235
gene id: 526227:MESIL_RS02235
uniprot id: D7B9U4
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

526227:MESIL RS04025
gene id: 526227:MESIL_RS04025
uniprot id: D7BBE3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS10075
gene id: 526227:MESIL_RS10075
uniprot id: D7BH23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

526227:MESIL RS12145
gene id: 526227:MESIL_RS12145
uniprot id: D7BAD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526227:MESIL RS16950
gene id: 526227:MESIL_RS16950
uniprot id: D7BJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

526227:MESIL RS03125
gene id: 526227:MESIL_RS03125
uniprot id: D7BAM2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526227:MESIL RS10460
gene id: 526227:MESIL_RS10460
uniprot id: D7BH99
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526227:MESIL RS00830
gene id: 526227:MESIL_RS00830
uniprot id: D7BGV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

526227:MESIL RS05765
gene id: 526227:MESIL_RS05765
uniprot id: D7BDC5
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS00910
gene id: 526227:MESIL_RS00910
uniprot id: D7BGW9
names: Similarity
messages: Belongs to the DinB family.

526227:MESIL RS06700
gene id: 526227:MESIL_RS06700
uniprot id: D7BEI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

526227:MESIL RS09630
gene id: 526227:MESIL_RS09630
uniprot id: D7BDS7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

526227:MESIL RS00740
gene id: 526227:MESIL_RS00740
uniprot id: D7BGT6
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS09345
gene id: 526227:MESIL_RS09345
uniprot id: D7BGB7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

526227:MESIL RS15380
gene id: 526227:MESIL_RS15380
uniprot id: D7BE34
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

526227:MESIL RS12625
gene id: 526227:MESIL_RS12625
uniprot id: D7BAZ5
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS08230
gene id: 526227:MESIL_RS08230
uniprot id: D7BFG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

526227:MESIL RS12420
gene id: 526227:MESIL_RS12420
uniprot id: D7BAV3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

526227:MESIL RS14710
gene id: 526227:MESIL_RS14710
uniprot id: D7BDE4
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS16595
gene id: 526227:MESIL_RS16595
uniprot id: D7BIV5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS01190
gene id: 526227:MESIL_RS01190
uniprot id: D7BHE0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS01570
gene id: 526227:MESIL_RS01570
uniprot id: D7BHL4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

526227:MESIL RS06875
gene id: 526227:MESIL_RS06875
uniprot id: D7BEL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526227:MESIL RS02990
gene id: 526227:MESIL_RS02990
uniprot id: D7BAJ6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

526227:MESIL RS02105
gene id: 526227:MESIL_RS02105
uniprot id: D7BI78
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS13055
gene id: 526227:MESIL_RS13055
uniprot id: D7BBJ0
names: Similarity
messages: Belongs to the MreC family.

526227:MESIL RS01795
gene id: 526227:MESIL_RS01795
uniprot id: D7BI20
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

526227:MESIL RS08325
gene id: 526227:MESIL_RS08325
uniprot id: D7BFI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

526227:MESIL RS13445
gene id: 526227:MESIL_RS13445
uniprot id: D7BBR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS04780
gene id: 526227:MESIL_RS04780
uniprot id: D7BCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS05060
gene id: 526227:MESIL_RS05060
uniprot id: D7BCM2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

526227:MESIL RS02280
gene id: 526227:MESIL_RS02280
uniprot id: D7B9V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

526227:MESIL RS11020
gene id: 526227:MESIL_RS11020
uniprot id: D7BHX0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

526227:MESIL RS14505
gene id: 526227:MESIL_RS14505
uniprot id: D7BCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

526227:MESIL RS11780
gene id: 526227:MESIL_RS11780
uniprot id: D7BA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

526227:MESIL RS15055
gene id: 526227:MESIL_RS15055
uniprot id: D7BDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

526227:MESIL RS01705
gene id: 526227:MESIL_RS01705
uniprot id: D7BI02
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

526227:MESIL RS01020
gene id: 526227:MESIL_RS01020
uniprot id: D7BGY8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

526227:MESIL RS06420
gene id: 526227:MESIL_RS06420
uniprot id: D7BEC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526227:MESIL RS17945
gene id: 526227:MESIL_RS17945
uniprot id: D7BJL0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

526227:MESIL RS11445
gene id: 526227:MESIL_RS11445
uniprot id: D7BIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

526227:MESIL RS16635
gene id: 526227:MESIL_RS16635
uniprot id: D7BEN6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

526227:MESIL RS11605
gene id: 526227:MESIL_RS11605
uniprot id: D7BIJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

526227:MESIL RS00360
gene id: 526227:MESIL_RS00360
uniprot id: D7BG97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

526227:MESIL RS04320
gene id: 526227:MESIL_RS04320
uniprot id: D7BBW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

526227:MESIL RS15415
gene id: 526227:MESIL_RS15415
uniprot id: D7BE41
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

526227:MESIL RS07155
gene id: 526227:MESIL_RS07155
uniprot id: D7BEW0
names: Similarity
messages: Belongs to the peptidase S41A family.

526227:MESIL RS10815
gene id: 526227:MESIL_RS10815
uniprot id: D7BHT1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS05420
gene id: 526227:MESIL_RS05420
uniprot id: D7BD57
names: Subcellular Location Annotation
messages: Nucleus

526227:MESIL RS09450
gene id: 526227:MESIL_RS09450
uniprot id: D7BGD7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS05720
gene id: 526227:MESIL_RS05720
uniprot id: D7BDB6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

526227:MESIL RS12445
gene id: 526227:MESIL_RS12445
uniprot id: D7BAV9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS07880
gene id: 526227:MESIL_RS07880
uniprot id: D7BFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS04355
gene id: 526227:MESIL_RS04355
uniprot id: D7BBX2
names: Similarity
messages: Belongs to the CinA family.

526227:MESIL RS10375
gene id: 526227:MESIL_RS10375
uniprot id: D7BH82
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

526227:MESIL RS12620
gene id: 526227:MESIL_RS12620
uniprot id: D7BAZ4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

526227:MESIL RS00410
gene id: 526227:MESIL_RS00410
uniprot id: D7BGA7
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

526227:MESIL RS08275
gene id: 526227:MESIL_RS08275
uniprot id: D7BFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

526227:MESIL RS08180
gene id: 526227:MESIL_RS08180
uniprot id: D7BFF8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS14495
gene id: 526227:MESIL_RS14495
uniprot id: D7BCZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

526227:MESIL RS04205
gene id: 526227:MESIL_RS04205
uniprot id: D7BBU2
names: Similarity
messages: Belongs to the peptidase S33 family.

526227:MESIL RS10300
gene id: 526227:MESIL_RS10300
uniprot id: D7BH66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS09355
gene id: 526227:MESIL_RS09355
uniprot id: D7BGB9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS14250
gene id: 526227:MESIL_RS14250
uniprot id: D7BCU3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

526227:MESIL RS08620
gene id: 526227:MESIL_RS08620
uniprot id: D7BFP3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

526227:MESIL RS11520
gene id: 526227:MESIL_RS11520
uniprot id: D7BIH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526227:MESIL RS11120
gene id: 526227:MESIL_RS11120
uniprot id: D7BIA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS14680
gene id: 526227:MESIL_RS14680
uniprot id: D7BDD8
names: Similarity
messages: Belongs to the SCO1/2 family.

526227:MESIL RS17205
gene id: 526227:MESIL_RS17205
uniprot id: D7BIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS05055
gene id: 526227:MESIL_RS05055
uniprot id: D7BCM1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

526227:MESIL RS10480
gene id: 526227:MESIL_RS10480
uniprot id: D7BHA2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

526227:MESIL RS03360
gene id: 526227:MESIL_RS03360
uniprot id: D7BAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

526227:MESIL RS07645
gene id: 526227:MESIL_RS07645
uniprot id: D7BF58
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

526227:MESIL RS13700
gene id: 526227:MESIL_RS13700
uniprot id: D7BC75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS12790
gene id: 526227:MESIL_RS12790
uniprot id: D7BB26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

526227:MESIL RS15140
gene id: 526227:MESIL_RS15140
uniprot id: D7BDM7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

526227:MESIL RS15020
gene id: 526227:MESIL_RS15020
uniprot id: D7BDK3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

526227:MESIL RS11720
gene id: 526227:MESIL_RS11720
uniprot id: D7BA55
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS15725
gene id: 526227:MESIL_RS15725
uniprot id: D7BE97
names: Cofactor
messages: Binds 1 FAD per subunit.

526227:MESIL RS14750
gene id: 526227:MESIL_RS14750
uniprot id: D7BDF2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

526227:MESIL RS00340
gene id: 526227:MESIL_RS00340
uniprot id: D7BG93
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526227:MESIL RS13685
gene id: 526227:MESIL_RS13685
uniprot id: D7BC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS08960
gene id: 526227:MESIL_RS08960
uniprot id: D7BFV7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

526227:MESIL RS13715
gene id: 526227:MESIL_RS13715
uniprot id: D7BC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS18055
gene id: 526227:MESIL_RS18055
uniprot id: D7BJN0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

526227:MESIL RS04990
gene id: 526227:MESIL_RS04990
uniprot id: D7BCL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

526227:MESIL RS00270
gene id: 526227:MESIL_RS00270
uniprot id: D7BG79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

526227:MESIL RS15130
gene id: 526227:MESIL_RS15130
uniprot id: D7BDM5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

526227:MESIL RS10950
gene id: 526227:MESIL_RS10950
uniprot id: D7BHV7
names: Similarity
messages: Belongs to the ycf81 family.

526227:MESIL RS16200
gene id: 526227:MESIL_RS16200
uniprot id: D7BIN1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS01455
gene id: 526227:MESIL_RS01455
uniprot id: D7BHJ5
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

526227:MESIL RS08160
gene id: 526227:MESIL_RS08160
uniprot id: D7BFF4
names: Similarity
messages: Belongs to the citrate synthase family.

526227:MESIL RS05480
gene id: 526227:MESIL_RS05480
uniprot id: D7BD70
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12405
gene id: 526227:MESIL_RS12405
uniprot id: D7BAV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

526227:MESIL RS12705
gene id: 526227:MESIL_RS12705
uniprot id: D7BB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

526227:MESIL RS12480
gene id: 526227:MESIL_RS12480
uniprot id: D7BAW6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

526227:MESIL RS16405
gene id: 526227:MESIL_RS16405
uniprot id: D7BIR8
names: Similarity
messages: Belongs to the DinB family.

526227:MESIL RS06495
gene id: 526227:MESIL_RS06495
uniprot id: D7BEE0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526227:MESIL RS00490
gene id: 526227:MESIL_RS00490
uniprot id: D7BGN7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

526227:MESIL RS10355
gene id: 526227:MESIL_RS10355
uniprot id: D7BH77
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

526227:MESIL RS17365
gene id: 526227:MESIL_RS17365
uniprot id: D7BJA5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

526227:MESIL RS14345
gene id: 526227:MESIL_RS14345
uniprot id: D7BCW2
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS06380
gene id: 526227:MESIL_RS06380
uniprot id: D7BE09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

526227:MESIL RS03795
gene id: 526227:MESIL_RS03795
uniprot id: D7BB97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS10360
gene id: 526227:MESIL_RS10360
uniprot id: D7BH78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS11410
gene id: 526227:MESIL_RS11410
uniprot id: D7BIF9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

526227:MESIL RS11225
gene id: 526227:MESIL_RS11225
uniprot id: D7BIC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

526227:MESIL RS01950
gene id: 526227:MESIL_RS01950
uniprot id: D7BI48
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

526227:MESIL RS08585
gene id: 526227:MESIL_RS08585
uniprot id: D7BFN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

526227:MESIL RS17865
gene id: 526227:MESIL_RS17865
uniprot id: D7BJJ5
names: Similarity
messages: Belongs to the ParB family.

526227:MESIL RS14575
gene id: 526227:MESIL_RS14575
uniprot id: D7BD06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

526227:MESIL RS13955
gene id: 526227:MESIL_RS13955
uniprot id: D7BCC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526227:MESIL RS12540
gene id: 526227:MESIL_RS12540
uniprot id: D7BAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS04275
gene id: 526227:MESIL_RS04275
uniprot id: D7BBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

526227:MESIL RS13060
gene id: 526227:MESIL_RS13060
uniprot id: D7BBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

526227:MESIL RS02265
gene id: 526227:MESIL_RS02265
uniprot id: D7B9V0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

526227:MESIL RS03135
gene id: 526227:MESIL_RS03135
uniprot id: D7BAM4
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS04235
gene id: 526227:MESIL_RS04235
uniprot id: D7BBU8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS03850
gene id: 526227:MESIL_RS03850
uniprot id: D7BBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

526227:MESIL RS00880
gene id: 526227:MESIL_RS00880
uniprot id: D7BGW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

526227:MESIL RS02290
gene id: 526227:MESIL_RS02290
uniprot id: D7B9V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

526227:MESIL RS02185
gene id: 526227:MESIL_RS02185
uniprot id: D7BI94
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

526227:MESIL RS03570
gene id: 526227:MESIL_RS03570
uniprot id: D7BB56
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

526227:MESIL RS02060
gene id: 526227:MESIL_RS02060
uniprot id: D7BI69
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

526227:MESIL RS02200
gene id: 526227:MESIL_RS02200
uniprot id: D7BI97
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

526227:MESIL RS11880
gene id: 526227:MESIL_RS11880
uniprot id: D7BA87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

526227:MESIL RS14350
gene id: 526227:MESIL_RS14350
uniprot id: D7BCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

526227:MESIL RS13015
gene id: 526227:MESIL_RS13015
uniprot id: D7BBI2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

526227:MESIL RS14000
gene id: 526227:MESIL_RS14000
uniprot id: D7BCD3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

526227:MESIL RS02000
gene id: 526227:MESIL_RS02000
uniprot id: D7BI58
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

526227:MESIL RS03770
gene id: 526227:MESIL_RS03770
uniprot id: D7BB93
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS15680
gene id: 526227:MESIL_RS15680
uniprot id: D7BE87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

526227:MESIL RS08135
gene id: 526227:MESIL_RS08135
uniprot id: D7BFF0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

526227:MESIL RS09820
gene id: 526227:MESIL_RS09820
uniprot id: D7BGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS02085
gene id: 526227:MESIL_RS02085
uniprot id: D7BI74
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS09015
gene id: 526227:MESIL_RS09015
uniprot id: D7BFW8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS03400
gene id: 526227:MESIL_RS03400
uniprot id: D7BAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS12100
gene id: 526227:MESIL_RS12100
uniprot id: D7BAD1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS00015
gene id: 526227:MESIL_RS00015
uniprot id: D7BG30
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

526227:MESIL RS16095
gene id: 526227:MESIL_RS16095
uniprot id: D7BES4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

526227:MESIL RS14500
gene id: 526227:MESIL_RS14500
uniprot id: D7BCZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

526227:MESIL RS15910
gene id: 526227:MESIL_RS15910
uniprot id: D7BEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

526227:MESIL RS00110
gene id: 526227:MESIL_RS00110
uniprot id: D7BG48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

526227:MESIL RS11270
gene id: 526227:MESIL_RS11270
uniprot id: D7BID3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS05650
gene id: 526227:MESIL_RS05650
uniprot id: D7BDA3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

526227:MESIL RS16030
gene id: 526227:MESIL_RS16030
uniprot id: D7BER2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526227:MESIL RS03605
gene id: 526227:MESIL_RS03605
uniprot id: D7BB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

526227:MESIL RS14550
gene id: 526227:MESIL_RS14550
uniprot id: D7BD01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

526227:MESIL RS17115
gene id: 526227:MESIL_RS17115
uniprot id: D7BJ59
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

526227:MESIL RS15655
gene id: 526227:MESIL_RS15655
uniprot id: D7BE82
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

526227:MESIL RS03750
gene id: 526227:MESIL_RS03750
uniprot id: D7BB89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS13270
gene id: 526227:MESIL_RS13270
uniprot id: D7BBN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

526227:MESIL RS14005
gene id: 526227:MESIL_RS14005
uniprot id: D7BCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

526227:MESIL RS13000
gene id: 526227:MESIL_RS13000
uniprot id: D7BBH9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

526227:MESIL RS06530
gene id: 526227:MESIL_RS06530
uniprot id: D7BEE6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

526227:MESIL RS12865
gene id: 526227:MESIL_RS12865
uniprot id: D7BBF3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

526227:MESIL RS15040
gene id: 526227:MESIL_RS15040
uniprot id: D7BDK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS16745
gene id: 526227:MESIL_RS16745
uniprot id: D7BIY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS04950
gene id: 526227:MESIL_RS04950
uniprot id: D7BCK2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

526227:MESIL RS03000
gene id: 526227:MESIL_RS03000
uniprot id: D7BAJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

526227:MESIL RS16070
gene id: 526227:MESIL_RS16070
uniprot id: D7BER9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS17085
gene id: 526227:MESIL_RS17085
uniprot id: D7BJ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS15585
gene id: 526227:MESIL_RS15585
uniprot id: D7BE69
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

526227:MESIL RS07825
gene id: 526227:MESIL_RS07825
uniprot id: D7BF94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

526227:MESIL RS18695
gene id: 526227:MESIL_RS18695
uniprot id: D7BDH0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12785
gene id: 526227:MESIL_RS12785
uniprot id: D7BB25
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526227:MESIL RS13950
gene id: 526227:MESIL_RS13950
uniprot id: D7BCC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526227:MESIL RS03775
gene id: 526227:MESIL_RS03775
uniprot id: D7BB94
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS14030
gene id: 526227:MESIL_RS14030
uniprot id: D7BCD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS15620
gene id: 526227:MESIL_RS15620
uniprot id: D7BE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

526227:MESIL RS00545
gene id: 526227:MESIL_RS00545
uniprot id: D7BGP7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS09865
gene id: 526227:MESIL_RS09865
uniprot id: D7BGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

526227:MESIL RS08390
gene id: 526227:MESIL_RS08390
uniprot id: D7BFJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

526227:MESIL RS04105
gene id: 526227:MESIL_RS04105
uniprot id: D7BBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

526227:MESIL RS04905
gene id: 526227:MESIL_RS04905
uniprot id: D7BCJ4
names: Subcellular Location Annotation
messages: Cytoplasm

526227:MESIL RS11265
gene id: 526227:MESIL_RS11265
uniprot id: D7BID2
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12065
gene id: 526227:MESIL_RS12065
uniprot id: D7BAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS05595
gene id: 526227:MESIL_RS05595
uniprot id: D7BD92
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS05270
gene id: 526227:MESIL_RS05270
uniprot id: D7BD28
names: Similarity
messages: Belongs to the DprA/Smf family.

526227:MESIL RS06415
gene id: 526227:MESIL_RS06415
uniprot id: D7BEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

526227:MESIL RS06425
gene id: 526227:MESIL_RS06425
uniprot id: D7BEC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526227:MESIL RS00070
gene id: 526227:MESIL_RS00070
uniprot id: D7BG40
names: Similarity
messages: Belongs to the P(II) protein family.

526227:MESIL RS15180
gene id: 526227:MESIL_RS15180
uniprot id: D7BDN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

526227:MESIL RS06625
gene id: 526227:MESIL_RS06625
uniprot id: D7BEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

526227:MESIL RS03715
gene id: 526227:MESIL_RS03715
uniprot id: D7BB82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

526227:MESIL RS16195
gene id: 526227:MESIL_RS16195
uniprot id: D7BIN0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12515
gene id: 526227:MESIL_RS12515
uniprot id: D7BAX3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS09470
gene id: 526227:MESIL_RS09470
uniprot id: D7BGE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

526227:MESIL RS05090
gene id: 526227:MESIL_RS05090
uniprot id: D7BCM8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

526227:MESIL RS07345
gene id: 526227:MESIL_RS07345
uniprot id: D7BEZ9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

526227:MESIL RS12495
gene id: 526227:MESIL_RS12495
uniprot id: D7BAW9
names: Similarity
messages: Belongs to the glutamine synthetase family.

526227:MESIL RS14795
gene id: 526227:MESIL_RS14795
uniprot id: D7BDG1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

526227:MESIL RS11240
gene id: 526227:MESIL_RS11240
uniprot id: D7BIC7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

526227:MESIL RS16255
gene id: 526227:MESIL_RS16255
uniprot id: D7BIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS09030
gene id: 526227:MESIL_RS09030
uniprot id: D7BFX1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS00920
gene id: 526227:MESIL_RS00920
uniprot id: D7BGX1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

526227:MESIL RS00655
gene id: 526227:MESIL_RS00655
uniprot id: D7BGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

526227:MESIL RS07585
gene id: 526227:MESIL_RS07585
uniprot id: D7BF47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

526227:MESIL RS10025
gene id: 526227:MESIL_RS10025
uniprot id: D7BH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS10235
gene id: 526227:MESIL_RS10235
uniprot id: D7BH53
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

526227:MESIL RS07405
gene id: 526227:MESIL_RS07405
uniprot id: D7BF10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

526227:MESIL RS07605
gene id: 526227:MESIL_RS07605
uniprot id: D7BF50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

526227:MESIL RS10115
gene id: 526227:MESIL_RS10115
uniprot id: D7BH31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

526227:MESIL RS07985
gene id: 526227:MESIL_RS07985
uniprot id: D7BFC2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS13695
gene id: 526227:MESIL_RS13695
uniprot id: D7BC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

526227:MESIL RS06555
gene id: 526227:MESIL_RS06555
uniprot id: D7BEF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526227:MESIL RS01550
gene id: 526227:MESIL_RS01550
uniprot id: D7BHL2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

526227:MESIL RS13040
gene id: 526227:MESIL_RS13040
uniprot id: D7BBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

526227:MESIL RS10595
gene id: 526227:MESIL_RS10595
uniprot id: D7BHN8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

526227:MESIL RS01655
gene id: 526227:MESIL_RS01655
uniprot id: D7BHZ2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

526227:MESIL RS04470
gene id: 526227:MESIL_RS04470
uniprot id: D7BBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS11850
gene id: 526227:MESIL_RS11850
uniprot id: D7BA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

526227:MESIL RS09335
gene id: 526227:MESIL_RS09335
uniprot id: D7BGB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

526227:MESIL RS10635
gene id: 526227:MESIL_RS10635
uniprot id: D7BHP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS09760
gene id: 526227:MESIL_RS09760
uniprot id: D7BGK1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

526227:MESIL RS01000
gene id: 526227:MESIL_RS01000
uniprot id: D7BGY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

526227:MESIL RS12485
gene id: 526227:MESIL_RS12485
uniprot id: D7BAW7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

526227:MESIL RS10085
gene id: 526227:MESIL_RS10085
uniprot id: D7BH25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

526227:MESIL RS13910
gene id: 526227:MESIL_RS13910
uniprot id: D7BCB5
names: Similarity
messages: Belongs to the universal stress protein A family.

526227:MESIL RS02715
gene id: 526227:MESIL_RS02715
uniprot id: D7BA37
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

526227:MESIL RS03610
gene id: 526227:MESIL_RS03610
uniprot id: D7BB64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

526227:MESIL RS03545
gene id: 526227:MESIL_RS03545
uniprot id: D7BB53
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

526227:MESIL RS06895
gene id: 526227:MESIL_RS06895
uniprot id: D7BEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS06395
gene id: 526227:MESIL_RS06395
uniprot id: D7BE12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

526227:MESIL RS05750
gene id: 526227:MESIL_RS05750
uniprot id: D7BDC2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

526227:MESIL RS09460
gene id: 526227:MESIL_RS09460
uniprot id: D7BGD9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

526227:MESIL RS04510
gene id: 526227:MESIL_RS04510
uniprot id: D7BC04
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

526227:MESIL RS11360
gene id: 526227:MESIL_RS11360
uniprot id: D7BIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

526227:MESIL RS16645
gene id: 526227:MESIL_RS16645
uniprot id: D7BIW6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526227:MESIL RS07875
gene id: 526227:MESIL_RS07875
uniprot id: D7BFA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS12840
gene id: 526227:MESIL_RS12840
uniprot id: D7BB36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

526227:MESIL RS14740
gene id: 526227:MESIL_RS14740
uniprot id: D7BDF0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526227:MESIL RS00565
gene id: 526227:MESIL_RS00565
uniprot id: D7BGQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

526227:MESIL RS02980
gene id: 526227:MESIL_RS02980
uniprot id: D7BAJ4
names: Similarity
messages: Belongs to the GSP E family.

526227:MESIL RS00010
gene id: 526227:MESIL_RS00010
uniprot id: D7BG29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

526227:MESIL RS05835
gene id: 526227:MESIL_RS05835
uniprot id: D7BDQ4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

526227:MESIL RS11765
gene id: 526227:MESIL_RS11765
uniprot id: D7BA65
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12605
gene id: 526227:MESIL_RS12605
uniprot id: D7BAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS06705
gene id: 526227:MESIL_RS06705
uniprot id: D7BEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

526227:MESIL RS04835
gene id: 526227:MESIL_RS04835
uniprot id: D7BCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS12395
gene id: 526227:MESIL_RS12395
uniprot id: D7BAU8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

526227:MESIL RS12750
gene id: 526227:MESIL_RS12750
uniprot id: D7BB18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

526227:MESIL RS03365
gene id: 526227:MESIL_RS03365
uniprot id: D7BAQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

526227:MESIL RS13140
gene id: 526227:MESIL_RS13140
uniprot id: D7BBK6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

526227:MESIL RS09435
gene id: 526227:MESIL_RS09435
uniprot id: D7BGD4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

526227:MESIL RS07800
gene id: 526227:MESIL_RS07800
uniprot id: D7BF89
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

526227:MESIL RS03475
gene id: 526227:MESIL_RS03475
uniprot id: D7BB40
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12050
gene id: 526227:MESIL_RS12050
uniprot id: D7BAC1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS08550
gene id: 526227:MESIL_RS08550
uniprot id: D7BFM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS04810
gene id: 526227:MESIL_RS04810
uniprot id: D7BCH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

526227:MESIL RS00815
gene id: 526227:MESIL_RS00815
uniprot id: D7BGV1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS00515
gene id: 526227:MESIL_RS00515
uniprot id: D7BGP2
names: Similarity
messages: Belongs to the universal stress protein A family.

526227:MESIL RS15945
gene id: 526227:MESIL_RS15945
uniprot id: D7BEP7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS09230
gene id: 526227:MESIL_RS09230
uniprot id: D7BG09
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS15355
gene id: 526227:MESIL_RS15355
uniprot id: D7BE29
names: Similarity
messages: Belongs to the FGGY kinase family.

526227:MESIL RS06645
gene id: 526227:MESIL_RS06645
uniprot id: D7BEH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526227:MESIL RS07010
gene id: 526227:MESIL_RS07010
uniprot id: D7BET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526227:MESIL RS00765
gene id: 526227:MESIL_RS00765
uniprot id: D7BGU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

526227:MESIL RS04080
gene id: 526227:MESIL_RS04080
uniprot id: D7BBR8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

526227:MESIL RS11300
gene id: 526227:MESIL_RS11300
uniprot id: D7BID9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

526227:MESIL RS07130
gene id: 526227:MESIL_RS07130
uniprot id: D7BEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

526227:MESIL RS03170
gene id: 526227:MESIL_RS03170
uniprot id: D7BAM9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

526227:MESIL RS05430
gene id: 526227:MESIL_RS05430
uniprot id: D7BD59
names: Subcellular Location Annotation
messages: Cytoplasm

526227:MESIL RS07165
gene id: 526227:MESIL_RS07165
uniprot id: D7BEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

526227:MESIL RS03345
gene id: 526227:MESIL_RS03345
uniprot id: D7BAQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

526227:MESIL RS12290
gene id: 526227:MESIL_RS12290
uniprot id: D7BAG6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

526227:MESIL RS07900
gene id: 526227:MESIL_RS07900
uniprot id: D7BFA9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526227:MESIL RS11060
gene id: 526227:MESIL_RS11060
uniprot id: D7BHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

526227:MESIL RS09255
gene id: 526227:MESIL_RS09255
uniprot id: D7BG14
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

526227:MESIL RS12955
gene id: 526227:MESIL_RS12955
uniprot id: D7BBH0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS14640
gene id: 526227:MESIL_RS14640
uniprot id: D7BD19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

526227:MESIL RS10365
gene id: 526227:MESIL_RS10365
uniprot id: D7BH79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

526227:MESIL RS07830
gene id: 526227:MESIL_RS07830
uniprot id: D7BF95
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

526227:MESIL RS11385
gene id: 526227:MESIL_RS11385
uniprot id: D7BIF4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

526227:MESIL RS13485
gene id: 526227:MESIL_RS13485
uniprot id: D7BC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

526227:MESIL RS11340
gene id: 526227:MESIL_RS11340
uniprot id: D7BIE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS08055
gene id: 526227:MESIL_RS08055
uniprot id: D7BFD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526227:MESIL RS11905
gene id: 526227:MESIL_RS11905
uniprot id: D7BA92
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

526227:MESIL RS11230
gene id: 526227:MESIL_RS11230
uniprot id: D7BIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

526227:MESIL RS04970
gene id: 526227:MESIL_RS04970
uniprot id: D7BCK6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

526227:MESIL RS11550
gene id: 526227:MESIL_RS11550
uniprot id: D7BII2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

526227:MESIL RS17270
gene id: 526227:MESIL_RS17270
uniprot id: D7BIM8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS17580
gene id: 526227:MESIL_RS17580
uniprot id: D7BJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS06835
gene id: 526227:MESIL_RS06835
uniprot id: D7BEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

526227:MESIL RS05730
gene id: 526227:MESIL_RS05730
uniprot id: D7BDB8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

526227:MESIL RS05900
gene id: 526227:MESIL_RS05900
uniprot id: D7BDR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

526227:MESIL RS08050
gene id: 526227:MESIL_RS08050
uniprot id: D7BFD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS09840
gene id: 526227:MESIL_RS09840
uniprot id: D7BGL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

526227:MESIL RS04130
gene id: 526227:MESIL_RS04130
uniprot id: D7BBS7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

526227:MESIL RS08460
gene id: 526227:MESIL_RS08460
uniprot id: D7BFL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

526227:MESIL RS10665
gene id: 526227:MESIL_RS10665
uniprot id: D7BHQ2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

526227:MESIL RS05125
gene id: 526227:MESIL_RS05125
uniprot id: D7BCN5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

526227:MESIL RS02955
gene id: 526227:MESIL_RS02955
uniprot id: D7BAJ2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526227:MESIL RS09505
gene id: 526227:MESIL_RS09505
uniprot id: D7BGE8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

526227:MESIL RS08165
gene id: 526227:MESIL_RS08165
uniprot id: D7BFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

526227:MESIL RS01820
gene id: 526227:MESIL_RS01820
uniprot id: D7BI25
names: Similarity
messages: Belongs to the UPF0102 family.

526227:MESIL RS05475
gene id: 526227:MESIL_RS05475
uniprot id: D7BD69
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

526227:MESIL RS06940
gene id: 526227:MESIL_RS06940
uniprot id: D7BEM8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

526227:MESIL RS15250
gene id: 526227:MESIL_RS15250
uniprot id: D7BDP8
names: Similarity
messages: Belongs to the histone deacetylase family.

526227:MESIL RS06640
gene id: 526227:MESIL_RS06640
uniprot id: D7BEH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

526227:MESIL RS10775
gene id: 526227:MESIL_RS10775
uniprot id: D7BHS3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS05370
gene id: 526227:MESIL_RS05370
uniprot id: D7BD47
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS15420
gene id: 526227:MESIL_RS15420
uniprot id: D7BE42
names: Similarity
messages: Belongs to the FGGY kinase family.

526227:MESIL RS13575
gene id: 526227:MESIL_RS13575
uniprot id: D7BC52
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

526227:MESIL RS11620
gene id: 526227:MESIL_RS11620
uniprot id: D7BIJ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526227:MESIL RS16985
gene id: 526227:MESIL_RS16985
uniprot id: D7BJ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

526227:MESIL RS10335
gene id: 526227:MESIL_RS10335
uniprot id: D7BH73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS10255
gene id: 526227:MESIL_RS10255
uniprot id: D7BH57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS14530
gene id: 526227:MESIL_RS14530
uniprot id: D7BCZ7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS09245
gene id: 526227:MESIL_RS09245
uniprot id: D7BG12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

526227:MESIL RS04220
gene id: 526227:MESIL_RS04220
uniprot id: D7BBU5
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

526227:MESIL RS10575
gene id: 526227:MESIL_RS10575
uniprot id: D7BHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS11005
gene id: 526227:MESIL_RS11005
uniprot id: D7BHW7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

526227:MESIL RS08040
gene id: 526227:MESIL_RS08040
uniprot id: D7BFD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS01370
gene id: 526227:MESIL_RS01370
uniprot id: D7BHH7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

526227:MESIL RS17420
gene id: 526227:MESIL_RS17420
uniprot id: D7BJB5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

526227:MESIL RS07420
gene id: 526227:MESIL_RS07420
uniprot id: D7BF14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

526227:MESIL RS14600
gene id: 526227:MESIL_RS14600
uniprot id: D7BD11
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

526227:MESIL RS00375
gene id: 526227:MESIL_RS00375
uniprot id: D7BGA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS11350
gene id: 526227:MESIL_RS11350
uniprot id: D7BIE8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS03910
gene id: 526227:MESIL_RS03910
uniprot id: D7BBC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

526227:MESIL RS13850
gene id: 526227:MESIL_RS13850
uniprot id: D7BCA3
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

526227:MESIL RS11180
gene id: 526227:MESIL_RS11180
uniprot id: D7BIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

526227:MESIL RS15685
gene id: 526227:MESIL_RS15685
uniprot id: D7BE88
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS14620
gene id: 526227:MESIL_RS14620
uniprot id: D7BD15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

526227:MESIL RS11465
gene id: 526227:MESIL_RS11465
uniprot id: D7BIH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

526227:MESIL RS04755
gene id: 526227:MESIL_RS04755
uniprot id: D7BCG5
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

526227:MESIL RS09750
gene id: 526227:MESIL_RS09750
uniprot id: D7BGJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

526227:MESIL RS11260
gene id: 526227:MESIL_RS11260
uniprot id: D7BID1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

526227:MESIL RS01650
gene id: 526227:MESIL_RS01650
uniprot id: D7BHZ1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

526227:MESIL RS09870
gene id: 526227:MESIL_RS09870
uniprot id: D7BGM3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS09075
gene id: 526227:MESIL_RS09075
uniprot id: D7BFX9
names: Similarity
messages: Belongs to the ArsC family.

526227:MESIL RS01715
gene id: 526227:MESIL_RS01715
uniprot id: D7BI04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS09930
gene id: 526227:MESIL_RS09930
uniprot id: D7BGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

526227:MESIL RS14595
gene id: 526227:MESIL_RS14595
uniprot id: D7BD10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

526227:MESIL RS01500
gene id: 526227:MESIL_RS01500
uniprot id: D7BHK4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

526227:MESIL RS05345
gene id: 526227:MESIL_RS05345
uniprot id: D7BD42
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526227:MESIL RS16670
gene id: 526227:MESIL_RS16670
uniprot id: D7BIX1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

526227:MESIL RS06660
gene id: 526227:MESIL_RS06660
uniprot id: D7BEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

526227:MESIL RS12985
gene id: 526227:MESIL_RS12985
uniprot id: D7BBH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS08600
gene id: 526227:MESIL_RS08600
uniprot id: D7BFN9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526227:MESIL RS07745
gene id: 526227:MESIL_RS07745
uniprot id: D7BF77
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL34 family.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS02125
gene id: 526227:MESIL_RS02125
uniprot id: D7BI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

526227:MESIL RS08395
gene id: 526227:MESIL_RS08395
uniprot id: D7BFJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

526227:MESIL RS06575
gene id: 526227:MESIL_RS06575
uniprot id: D7BEF6
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

526227:MESIL RS10265
gene id: 526227:MESIL_RS10265
uniprot id: D7BH59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

526227:MESIL RS04605
gene id: 526227:MESIL_RS04605
uniprot id: D7BC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS01490
gene id: 526227:MESIL_RS01490
uniprot id: D7BHK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526227:MESIL RS09205
gene id: 526227:MESIL_RS09205
uniprot id: D7BG04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

526227:MESIL RS16270
gene id: 526227:MESIL_RS16270
uniprot id: D7BIP3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

526227:MESIL RS08105
gene id: 526227:MESIL_RS08105
uniprot id: D7BFE4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526227:MESIL RS14525
gene id: 526227:MESIL_RS14525
uniprot id: D7BCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS17425
gene id: 526227:MESIL_RS17425
uniprot id: D7BJB6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

526227:MESIL RS16955
gene id: 526227:MESIL_RS16955
uniprot id: D7BJ28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

526227:MESIL RS09730
gene id: 526227:MESIL_RS09730
uniprot id: D7BGJ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526227:MESIL RS15185
gene id: 526227:MESIL_RS15185
uniprot id: D7BDN6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS10790
gene id: 526227:MESIL_RS10790
uniprot id: D7BHS6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

526227:MESIL RS03810
gene id: 526227:MESIL_RS03810
uniprot id: D7BBA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

526227:MESIL RS15525
gene id: 526227:MESIL_RS15525
uniprot id: D7BE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

526227:MESIL RS16370
gene id: 526227:MESIL_RS16370
uniprot id: D7BIR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

526227:MESIL RS14025
gene id: 526227:MESIL_RS14025
uniprot id: D7BCD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS02305
gene id: 526227:MESIL_RS02305
uniprot id: D7B9V8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS07435
gene id: 526227:MESIL_RS07435
uniprot id: D7BF17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526227:MESIL RS14535
gene id: 526227:MESIL_RS14535
uniprot id: D7BCZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

526227:MESIL RS14545
gene id: 526227:MESIL_RS14545
uniprot id: D7BD00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

526227:MESIL RS03305
gene id: 526227:MESIL_RS03305
uniprot id: D7BAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

526227:MESIL RS14625
gene id: 526227:MESIL_RS14625
uniprot id: D7BD16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

526227:MESIL RS05355
gene id: 526227:MESIL_RS05355
uniprot id: D7BD44
names: Similarity
messages: Belongs to the SAICAR synthetase family.

526227:MESIL RS15610
gene id: 526227:MESIL_RS15610
uniprot id: D7BE74
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

526227:MESIL RS05655
gene id: 526227:MESIL_RS05655
uniprot id: D7BDA4
names: Similarity
messages: Belongs to the peptidase S8 family.

526227:MESIL RS07160
gene id: 526227:MESIL_RS07160
uniprot id: D7BEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

526227:MESIL RS16375
gene id: 526227:MESIL_RS16375
uniprot id: D7BIR2
names: Similarity
messages: Belongs to the phosphoribulokinase family.

526227:MESIL RS02250
gene id: 526227:MESIL_RS02250
uniprot id: D7B9U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526227:MESIL RS17615
gene id: 526227:MESIL_RS17615
uniprot id: D7BJF0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526227:MESIL RS01140
gene id: 526227:MESIL_RS01140
uniprot id: D7BHD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

526227:MESIL RS01160
gene id: 526227:MESIL_RS01160
uniprot id: D7BHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

526227:MESIL RS01245
gene id: 526227:MESIL_RS01245
uniprot id: D7BHF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

526227:MESIL RS15050
gene id: 526227:MESIL_RS15050
uniprot id: D7BDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

526227:MESIL RS16185
gene id: 526227:MESIL_RS16185
uniprot id: D7BIM8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS11290
gene id: 526227:MESIL_RS11290
uniprot id: D7BID7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

526227:MESIL RS00090
gene id: 526227:MESIL_RS00090
uniprot id: D7BG44
names: Similarity
messages: Belongs to the PspA/IM30 family.

526227:MESIL RS13495
gene id: 526227:MESIL_RS13495
uniprot id: D7BC40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

526227:MESIL RS11640
gene id: 526227:MESIL_RS11640
uniprot id: D7BIJ9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

526227:MESIL RS12820
gene id: 526227:MESIL_RS12820
uniprot id: D7BB32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

526227:MESIL RS20620
gene id: 526227:MESIL_RS20620
uniprot id: D7BD37
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

526227:MESIL RS03830
gene id: 526227:MESIL_RS03830
uniprot id: D7BBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS05205
gene id: 526227:MESIL_RS05205
uniprot id: D7BCP9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS02070
gene id: 526227:MESIL_RS02070
uniprot id: D7BI71
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS10320
gene id: 526227:MESIL_RS10320
uniprot id: D7BH70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

526227:MESIL RS17185
gene id: 526227:MESIL_RS17185
uniprot id: D7BIP4
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

526227:MESIL RS05255
gene id: 526227:MESIL_RS05255
uniprot id: D7BD25
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS02430
gene id: 526227:MESIL_RS02430
uniprot id: D7B9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS03580
gene id: 526227:MESIL_RS03580
uniprot id: D7BB58
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

526227:MESIL RS12255
gene id: 526227:MESIL_RS12255
uniprot id: D7BAF9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS15735
gene id: 526227:MESIL_RS15735
uniprot id: D7BE99
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526227:MESIL RS15085
gene id: 526227:MESIL_RS15085
uniprot id: D7BDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

526227:MESIL RS10785
gene id: 526227:MESIL_RS10785
uniprot id: D7BHS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

526227:MESIL RS10935
gene id: 526227:MESIL_RS10935
uniprot id: D7BHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS14135
gene id: 526227:MESIL_RS14135
uniprot id: D7BCS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS10985
gene id: 526227:MESIL_RS10985
uniprot id: D7BHW4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

526227:MESIL RS07120
gene id: 526227:MESIL_RS07120
uniprot id: D7BEV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526227:MESIL RS16190
gene id: 526227:MESIL_RS16190
uniprot id: D7BIM9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS00520
gene id: 526227:MESIL_RS00520
uniprot id: D7BGP3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS01240
gene id: 526227:MESIL_RS01240
uniprot id: D7BHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

526227:MESIL RS03565
gene id: 526227:MESIL_RS03565
uniprot id: D7BB55
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

526227:MESIL RS03325
gene id: 526227:MESIL_RS03325
uniprot id: D7BAQ1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

526227:MESIL RS12020
gene id: 526227:MESIL_RS12020
uniprot id: D7BAB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

526227:MESIL RS13635
gene id: 526227:MESIL_RS13635
uniprot id: D7BC62
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

526227:MESIL RS14510
gene id: 526227:MESIL_RS14510
uniprot id: D7BCZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

526227:MESIL RS07815
gene id: 526227:MESIL_RS07815
uniprot id: D7BF92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

526227:MESIL RS09955
gene id: 526227:MESIL_RS09955
uniprot id: D7BH01
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

526227:MESIL RS11440
gene id: 526227:MESIL_RS11440
uniprot id: D7BIG5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

526227:MESIL RS15005
gene id: 526227:MESIL_RS15005
uniprot id: D7BDK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS17650
gene id: 526227:MESIL_RS17650
uniprot id: D7BJF7
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

526227:MESIL RS11250
gene id: 526227:MESIL_RS11250
uniprot id: D7BIC9
names: Similarity
messages: Belongs to the DapA family.

526227:MESIL RS09500
gene id: 526227:MESIL_RS09500
uniprot id: D7BGE7
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS11235
gene id: 526227:MESIL_RS11235
uniprot id: D7BIC6
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS09190
gene id: 526227:MESIL_RS09190
uniprot id: D7BG01
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

526227:MESIL RS12330
gene id: 526227:MESIL_RS12330
uniprot id: D7BAT5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

526227:MESIL RS05275
gene id: 526227:MESIL_RS05275
uniprot id: D7BD29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

526227:MESIL RS13420
gene id: 526227:MESIL_RS13420
uniprot id: D7BBR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

526227:MESIL RS00845
gene id: 526227:MESIL_RS00845
uniprot id: D7BGV7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

526227:MESIL RS14110
gene id: 526227:MESIL_RS14110
uniprot id: D7BCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS10250
gene id: 526227:MESIL_RS10250
uniprot id: D7BH56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

526227:MESIL RS14130
gene id: 526227:MESIL_RS14130
uniprot id: D7BCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

526227:MESIL RS10160
gene id: 526227:MESIL_RS10160
uniprot id: D7BH38
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS04745
gene id: 526227:MESIL_RS04745
uniprot id: D7BCG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

526227:MESIL RS12760
gene id: 526227:MESIL_RS12760
uniprot id: D7BB20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

526227:MESIL RS15025
gene id: 526227:MESIL_RS15025
uniprot id: D7BDK4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

526227:MESIL RS08975
gene id: 526227:MESIL_RS08975
uniprot id: D7BFW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

526227:MESIL RS01825
gene id: 526227:MESIL_RS01825
uniprot id: D7BI26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS12980
gene id: 526227:MESIL_RS12980
uniprot id: D7BBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS00495
gene id: 526227:MESIL_RS00495
uniprot id: D7BGN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS12545
gene id: 526227:MESIL_RS12545
uniprot id: D7BAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS02190
gene id: 526227:MESIL_RS02190
uniprot id: D7BI95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

526227:MESIL RS07300
gene id: 526227:MESIL_RS07300
uniprot id: D7BEY9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS05440
gene id: 526227:MESIL_RS05440
uniprot id: D7BD61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

526227:MESIL RS09395
gene id: 526227:MESIL_RS09395
uniprot id: D7BGC7
names: Similarity
messages: Belongs to the LOG family.

526227:MESIL RS04585
gene id: 526227:MESIL_RS04585
uniprot id: D7BC20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526227:MESIL RS01585
gene id: 526227:MESIL_RS01585
uniprot id: D7BHL7
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS13475
gene id: 526227:MESIL_RS13475
uniprot id: D7BC36
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

526227:MESIL RS09850
gene id: 526227:MESIL_RS09850
uniprot id: D7BGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

526227:MESIL RS17125
gene id: 526227:MESIL_RS17125
uniprot id: D7BJ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

526227:MESIL RS01520
gene id: 526227:MESIL_RS01520
uniprot id: D7BHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

526227:MESIL RS01880
gene id: 526227:MESIL_RS01880
uniprot id: D7BI37
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS04910
gene id: 526227:MESIL_RS04910
uniprot id: D7BCJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

526227:MESIL RS15895
gene id: 526227:MESIL_RS15895
uniprot id: D7BEN8
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS16655
gene id: 526227:MESIL_RS16655
uniprot id: D7BIW8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526227:MESIL RS03955
gene id: 526227:MESIL_RS03955
uniprot id: D7BBC9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

526227:MESIL RS05120
gene id: 526227:MESIL_RS05120
uniprot id: D7BCN4
names: Similarity
messages: Belongs to the UxaA family.

526227:MESIL RS12375
gene id: 526227:MESIL_RS12375
uniprot id: D7BAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS02045
gene id: 526227:MESIL_RS02045
uniprot id: D7BI66
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS03455
gene id: 526227:MESIL_RS03455
uniprot id: D7BAS4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

526227:MESIL RS01960
gene id: 526227:MESIL_RS01960
uniprot id: D7BI50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

526227:MESIL RS11655
gene id: 526227:MESIL_RS11655
uniprot id: D7BIK2
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS04805
gene id: 526227:MESIL_RS04805
uniprot id: D7BCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

526227:MESIL RS12690
gene id: 526227:MESIL_RS12690
uniprot id: D7BB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS00020
gene id: 526227:MESIL_RS00020
uniprot id: D7BG31
names: Similarity
messages: Belongs to the pyruvate kinase family.

526227:MESIL RS09095
gene id: 526227:MESIL_RS09095
uniprot id: D7BFY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

526227:MESIL RS09755
gene id: 526227:MESIL_RS09755
uniprot id: D7BGK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

526227:MESIL RS16680
gene id: 526227:MESIL_RS16680
uniprot id: D7BIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

526227:MESIL RS12920
gene id: 526227:MESIL_RS12920
uniprot id: D7BBG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

526227:MESIL RS04360
gene id: 526227:MESIL_RS04360
uniprot id: D7BBX3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

526227:MESIL RS14555
gene id: 526227:MESIL_RS14555
uniprot id: D7BD02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

526227:MESIL RS17640
gene id: 526227:MESIL_RS17640
uniprot id: D7BJF5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

526227:MESIL RS12370
gene id: 526227:MESIL_RS12370
uniprot id: D7BAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS05360
gene id: 526227:MESIL_RS05360
uniprot id: D7BD45
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

526227:MESIL RS13995
gene id: 526227:MESIL_RS13995
uniprot id: D7BCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS16035
gene id: 526227:MESIL_RS16035
uniprot id: D7BER3
names: Similarity
messages: Belongs to the threonine aldolase family.

526227:MESIL RS12310
gene id: 526227:MESIL_RS12310
uniprot id: D7BAT1
names: Similarity
messages: Belongs to the peptidase S1C family.

526227:MESIL RS06430
gene id: 526227:MESIL_RS06430
uniprot id: D7BEC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526227:MESIL RS09065
gene id: 526227:MESIL_RS09065
uniprot id: D7BFX8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526227:MESIL RS10965
gene id: 526227:MESIL_RS10965
uniprot id: D7BHW0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

526227:MESIL RS01265
gene id: 526227:MESIL_RS01265
uniprot id: D7BHF6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

526227:MESIL RS14615
gene id: 526227:MESIL_RS14615
uniprot id: D7BD14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

526227:MESIL RS07380
gene id: 526227:MESIL_RS07380
uniprot id: D7BF05
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

526227:MESIL RS05930
gene id: 526227:MESIL_RS05930
uniprot id: D7BDR9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526227:MESIL RS11205
gene id: 526227:MESIL_RS11205
uniprot id: D7BIC0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS03825
gene id: 526227:MESIL_RS03825
uniprot id: D7BBA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

526227:MESIL RS13720
gene id: 526227:MESIL_RS13720
uniprot id: D7BC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS13395
gene id: 526227:MESIL_RS13395
uniprot id: D7BBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

526227:MESIL RS04165
gene id: 526227:MESIL_RS04165
uniprot id: D7BBT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS12455
gene id: 526227:MESIL_RS12455
uniprot id: D7BAW1
names: Similarity
messages: Belongs to the CutA family.

526227:MESIL RS15205
gene id: 526227:MESIL_RS15205
uniprot id: D7BDP0
names: Similarity
messages: Belongs to the thioredoxin family.

526227:MESIL RS14700
gene id: 526227:MESIL_RS14700
uniprot id: D7BDE2
names: Similarity
messages: Belongs to the peptidase C56 family.

526227:MESIL RS10960
gene id: 526227:MESIL_RS10960
uniprot id: D7BHV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

526227:MESIL RS05145
gene id: 526227:MESIL_RS05145
uniprot id: D7BCN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS04615
gene id: 526227:MESIL_RS04615
uniprot id: D7BC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS09400
gene id: 526227:MESIL_RS09400
uniprot id: D7BGC8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

526227:MESIL RS12880
gene id: 526227:MESIL_RS12880
uniprot id: D7BBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

526227:MESIL RS06335
gene id: 526227:MESIL_RS06335
uniprot id: D7BE00
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

526227:MESIL RS10155
gene id: 526227:MESIL_RS10155
uniprot id: D7BH37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

526227:MESIL RS16075
gene id: 526227:MESIL_RS16075
uniprot id: D7BES0
names: Similarity
messages: Belongs to the ParB family.

526227:MESIL RS15015
gene id: 526227:MESIL_RS15015
uniprot id: D7BDK2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

526227:MESIL RS01375
gene id: 526227:MESIL_RS01375
uniprot id: D7BHH9
names: Similarity
messages: Belongs to the NAD synthetase family.

526227:MESIL RS16570
gene id: 526227:MESIL_RS16570
uniprot id: D7BIV0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS11210
gene id: 526227:MESIL_RS11210
uniprot id: D7BIC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

526227:MESIL RS10955
gene id: 526227:MESIL_RS10955
uniprot id: D7BHV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

526227:MESIL RS10435
gene id: 526227:MESIL_RS10435
uniprot id: D7BH94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

526227:MESIL RS03415
gene id: 526227:MESIL_RS03415
uniprot id: D7BAR9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

526227:MESIL RS09775
gene id: 526227:MESIL_RS09775
uniprot id: D7BGK4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

526227:MESIL RS07415
gene id: 526227:MESIL_RS07415
uniprot id: D7BF12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

526227:MESIL RS13920
gene id: 526227:MESIL_RS13920
uniprot id: D7BCB7
names: Similarity
messages: Belongs to the UPF0166 family.

526227:MESIL RS13005
gene id: 526227:MESIL_RS13005
uniprot id: D7BBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS09805
gene id: 526227:MESIL_RS09805
uniprot id: D7BGL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526227:MESIL RS04740
gene id: 526227:MESIL_RS04740
uniprot id: D7BCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

526227:MESIL RS12460
gene id: 526227:MESIL_RS12460
uniprot id: D7BAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

526227:MESIL RS12120
gene id: 526227:MESIL_RS12120
uniprot id: D7BAD4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526227:MESIL RS02975
gene id: 526227:MESIL_RS02975
uniprot id: D7BAJ3
names: Similarity
messages: Belongs to the GSP E family.

526227:MESIL RS09480
gene id: 526227:MESIL_RS09480
uniprot id: D7BGE3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS04890
gene id: 526227:MESIL_RS04890
uniprot id: D7BCJ1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

526227:MESIL RS04230
gene id: 526227:MESIL_RS04230
uniprot id: D7BBU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

526227:MESIL RS08970
gene id: 526227:MESIL_RS08970
uniprot id: D7BFV9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

526227:MESIL RS04380
gene id: 526227:MESIL_RS04380
uniprot id: D7BBX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS11785
gene id: 526227:MESIL_RS11785
uniprot id: D7BA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

526227:MESIL RS03560
gene id: 526227:MESIL_RS03560
uniprot id: D7BB54
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

526227:MESIL RS16935
gene id: 526227:MESIL_RS16935
uniprot id: D7BJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

526227:MESIL RS17180
gene id: 526227:MESIL_RS17180
uniprot id: D7BIP5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

526227:MESIL RS05810
gene id: 526227:MESIL_RS05810
uniprot id: D7BDD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

526227:MESIL RS18200
gene id: 526227:MESIL_RS18200
uniprot id: D7BJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

526227:MESIL RS10770
gene id: 526227:MESIL_RS10770
uniprot id: D7BHS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

526227:MESIL RS05755
gene id: 526227:MESIL_RS05755
uniprot id: D7BDC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

526227:MESIL RS07995
gene id: 526227:MESIL_RS07995
uniprot id: D7BFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS10065
gene id: 526227:MESIL_RS10065
uniprot id: D7BH21
names: Similarity
messages: Belongs to the Fur family.

526227:MESIL RS04850
gene id: 526227:MESIL_RS04850
uniprot id: D7BCI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS01210
gene id: 526227:MESIL_RS01210
uniprot id: D7BHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

526227:MESIL RS02875
gene id: 526227:MESIL_RS02875
uniprot id: D7BAH8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

526227:MESIL RS12745
gene id: 526227:MESIL_RS12745
uniprot id: D7BB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS15010
gene id: 526227:MESIL_RS15010
uniprot id: D7BDK1
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

526227:MESIL RS00080
gene id: 526227:MESIL_RS00080
uniprot id: D7BG42
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

526227:MESIL RS14610
gene id: 526227:MESIL_RS14610
uniprot id: D7BD13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

526227:MESIL RS06465
gene id: 526227:MESIL_RS06465
uniprot id: D7BED4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526227:MESIL RS15800
gene id: 526227:MESIL_RS15800
uniprot id: D7BEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS04410
gene id: 526227:MESIL_RS04410
uniprot id: D7BBY3
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

526227:MESIL RS14240
gene id: 526227:MESIL_RS14240
uniprot id: D7BCU1
names: Similarity
messages: Belongs to the BshC family.

526227:MESIL RS07550
gene id: 526227:MESIL_RS07550
uniprot id: D7BF39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

526227:MESIL RS03925
gene id: 526227:MESIL_RS03925
uniprot id: D7BBC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

526227:MESIL RS14210
gene id: 526227:MESIL_RS14210
uniprot id: D7BCT6
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS10055
gene id: 526227:MESIL_RS10055
uniprot id: D7BH19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

526227:MESIL RS13320
gene id: 526227:MESIL_RS13320
uniprot id: D7BBP4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

526227:MESIL RS07615
gene id: 526227:MESIL_RS07615
uniprot id: D7BF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

526227:MESIL RS11910
gene id: 526227:MESIL_RS11910
uniprot id: D7BA93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

526227:MESIL RS15600
gene id: 526227:MESIL_RS15600
uniprot id: D7BE72
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

526227:MESIL RS07730
gene id: 526227:MESIL_RS07730
uniprot id: D7BF74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

526227:MESIL RS09790
gene id: 526227:MESIL_RS09790
uniprot id: D7BGK7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

526227:MESIL RS04365
gene id: 526227:MESIL_RS04365
uniprot id: D7BBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

526227:MESIL RS07390
gene id: 526227:MESIL_RS07390
uniprot id: D7BF07
names: Similarity
messages: Belongs to the disproportionating enzyme family.

526227:MESIL RS05500
gene id: 526227:MESIL_RS05500
uniprot id: D7BD74
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

526227:MESIL RS17120
gene id: 526227:MESIL_RS17120
uniprot id: D7BJ60
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

526227:MESIL RS14475
gene id: 526227:MESIL_RS14475
uniprot id: D7BCY6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

526227:MESIL RS10150
gene id: 526227:MESIL_RS10150
uniprot id: D7BH36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

526227:MESIL RS10420
gene id: 526227:MESIL_RS10420
uniprot id: D7BH91
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

526227:MESIL RS10900
gene id: 526227:MESIL_RS10900
uniprot id: D7BHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526227:MESIL RS09250
gene id: 526227:MESIL_RS09250
uniprot id: D7BG13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

526227:MESIL RS05660
gene id: 526227:MESIL_RS05660
uniprot id: D7BDA5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

526227:MESIL RS12025
gene id: 526227:MESIL_RS12025
uniprot id: D7BAB6
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

526227:MESIL RS01280
gene id: 526227:MESIL_RS01280
uniprot id: D7BHF9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

526227:MESIL RS08270
gene id: 526227:MESIL_RS08270
uniprot id: D7BFH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

526227:MESIL RS04185
gene id: 526227:MESIL_RS04185
uniprot id: D7BBT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526227:MESIL RS07720
gene id: 526227:MESIL_RS07720
uniprot id: D7BF72
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

526227:MESIL RS02195
gene id: 526227:MESIL_RS02195
uniprot id: D7BI96
names: Similarity
messages: Belongs to the Dps family.

526227:MESIL RS03685
gene id: 526227:MESIL_RS03685
uniprot id: D7BB77
names: Similarity
messages: Belongs to the DEAD box helicase family.

526227:MESIL RS12075
gene id: 526227:MESIL_RS12075
uniprot id: D7BAC6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS07270
gene id: 526227:MESIL_RS07270
uniprot id: D7BEY3
names: Similarity
messages: Belongs to the UPF0173 family.

526227:MESIL RS05460
gene id: 526227:MESIL_RS05460
uniprot id: D7BD65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS09085
gene id: 526227:MESIL_RS09085
uniprot id: D7BFY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526227:MESIL RS13425
gene id: 526227:MESIL_RS13425
uniprot id: D7BBR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

526227:MESIL RS05505
gene id: 526227:MESIL_RS05505
uniprot id: D7BD75
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

526227:MESIL RS07320
gene id: 526227:MESIL_RS07320
uniprot id: D7BEZ3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

526227:MESIL RS09215
gene id: 526227:MESIL_RS09215
uniprot id: D7BG06
names: Similarity
messages: Belongs to the group II decarboxylase family.

526227:MESIL RS11650
gene id: 526227:MESIL_RS11650
uniprot id: D7BIK1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS11950
gene id: 526227:MESIL_RS11950
uniprot id: D7BAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS00860
gene id: 526227:MESIL_RS00860
uniprot id: D7BGW0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS07360
gene id: 526227:MESIL_RS07360
uniprot id: D7BF02
names: Similarity
messages: Belongs to the peptidase M16 family.

526227:MESIL RS09875
gene id: 526227:MESIL_RS09875
uniprot id: D7BGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

526227:MESIL RS03290
gene id: 526227:MESIL_RS03290
uniprot id: D7BAP4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

526227:MESIL RS07560
gene id: 526227:MESIL_RS07560
uniprot id: D7BF42
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

526227:MESIL RS01915
gene id: 526227:MESIL_RS01915
uniprot id: D7BI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

526227:MESIL RS07895
gene id: 526227:MESIL_RS07895
uniprot id: D7BFA8
names: Similarity
messages: Belongs to the peptidase S8 family.

526227:MESIL RS04400
gene id: 526227:MESIL_RS04400
uniprot id: D7BBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

526227:MESIL RS10440
gene id: 526227:MESIL_RS10440
uniprot id: D7BH95
names: Similarity
messages: Belongs to the ComB family.

526227:MESIL RS06390
gene id: 526227:MESIL_RS06390
uniprot id: D7BE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

526227:MESIL RS04870
gene id: 526227:MESIL_RS04870
uniprot id: D7BCI7
names: Similarity
messages: Belongs to the histone deacetylase family.

526227:MESIL RS10340
gene id: 526227:MESIL_RS10340
uniprot id: D7BH74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS08245
gene id: 526227:MESIL_RS08245
uniprot id: D7BFG9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

526227:MESIL RS17255
gene id: 526227:MESIL_RS17255
uniprot id: D7BIN1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12965
gene id: 526227:MESIL_RS12965
uniprot id: D7BBH2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

526227:MESIL RS10455
gene id: 526227:MESIL_RS10455
uniprot id: D7BH98
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

526227:MESIL RS12850
gene id: 526227:MESIL_RS12850
uniprot id: D7BB38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

526227:MESIL RS14590
gene id: 526227:MESIL_RS14590
uniprot id: D7BD09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

526227:MESIL RS09770
gene id: 526227:MESIL_RS09770
uniprot id: D7BGK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

526227:MESIL RS04240
gene id: 526227:MESIL_RS04240
uniprot id: D7BBU9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

526227:MESIL RS07660
gene id: 526227:MESIL_RS07660
uniprot id: D7BF61
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

526227:MESIL RS07305
gene id: 526227:MESIL_RS07305
uniprot id: D7BEZ0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

526227:MESIL RS10090
gene id: 526227:MESIL_RS10090
uniprot id: D7BH26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

526227:MESIL RS04090
gene id: 526227:MESIL_RS04090
uniprot id: D7BBS0
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS02575
gene id: 526227:MESIL_RS02575
uniprot id: D7BA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

526227:MESIL RS06510
gene id: 526227:MESIL_RS06510
uniprot id: D7BEE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

526227:MESIL RS15915
gene id: 526227:MESIL_RS15915
uniprot id: D7BEP3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

526227:MESIL RS10275
gene id: 526227:MESIL_RS10275
uniprot id: D7BH61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS03480
gene id: 526227:MESIL_RS03480
uniprot id: D7BB41
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS06405
gene id: 526227:MESIL_RS06405
uniprot id: D7BE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526227:MESIL RS12010
gene id: 526227:MESIL_RS12010
uniprot id: D7BAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS03655
gene id: 526227:MESIL_RS03655
uniprot id: D7BB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS05485
gene id: 526227:MESIL_RS05485
uniprot id: D7BD71
names: Similarity
messages: Belongs to the UPF0111 family.

526227:MESIL RS11860
gene id: 526227:MESIL_RS11860
uniprot id: D7BA84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

526227:MESIL RS16520
gene id: 526227:MESIL_RS16520
uniprot id: D7BIU0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526227:MESIL RS11430
gene id: 526227:MESIL_RS11430
uniprot id: D7BIG3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS14630
gene id: 526227:MESIL_RS14630
uniprot id: D7BC40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

526227:MESIL RS01250
gene id: 526227:MESIL_RS01250
uniprot id: D7BHF3
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS00005
gene id: 526227:MESIL_RS00005
uniprot id: D7BG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

526227:MESIL RS11185
gene id: 526227:MESIL_RS11185
uniprot id: D7BIB6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

526227:MESIL RS09855
gene id: 526227:MESIL_RS09855
uniprot id: D7BGM0
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

526227:MESIL RS12250
gene id: 526227:MESIL_RS12250
uniprot id: D7BAF8
names: Similarity
messages: Belongs to the asp23 family.

526227:MESIL RS07245
gene id: 526227:MESIL_RS07245
uniprot id: D7BEX8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

526227:MESIL RS04015
gene id: 526227:MESIL_RS04015
uniprot id: D7BBE1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

526227:MESIL RS01385
gene id: 526227:MESIL_RS01385
uniprot id: D7BHI1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS07765
gene id: 526227:MESIL_RS07765
uniprot id: D7BF81
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS09275
gene id: 526227:MESIL_RS09275
uniprot id: D7BG19
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

526227:MESIL RS09125
gene id: 526227:MESIL_RS09125
uniprot id: D7BFY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS02015
gene id: 526227:MESIL_RS02015
uniprot id: D7BI62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS14400
gene id: 526227:MESIL_RS14400
uniprot id: D7BCX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

526227:MESIL RS01810
gene id: 526227:MESIL_RS01810
uniprot id: D7BI23
names: Similarity
messages: Belongs to the UbiD family.

526227:MESIL RS20180
gene id: 526227:MESIL_RS20180
uniprot id: D7BJN7
names: Similarity
messages: Belongs to the peptidase C40 family.

526227:MESIL RS05105
gene id: 526227:MESIL_RS05105
uniprot id: D7BCN1
names: Cofactor
messages: Can also use Mn(2+) ion.

526227:MESIL RS04825
gene id: 526227:MESIL_RS04825
uniprot id: D7BCH8
names: Similarity
messages: Belongs to the DinB family.

526227:MESIL RS15985
gene id: 526227:MESIL_RS15985
uniprot id: D7BEQ3
names: Similarity
messages: Belongs to the universal stress protein A family.

526227:MESIL RS15805
gene id: 526227:MESIL_RS15805
uniprot id: D7BEA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS00455
gene id: 526227:MESIL_RS00455
uniprot id: D7BGB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS10880
gene id: 526227:MESIL_RS10880
uniprot id: D7BHU4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

526227:MESIL RS11195
gene id: 526227:MESIL_RS11195
uniprot id: D7BIB8
names: Similarity
messages: Belongs to the IMPACT family.

526227:MESIL RS15385
gene id: 526227:MESIL_RS15385
uniprot id: D7BE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS04065
gene id: 526227:MESIL_RS04065
uniprot id: D7BBF1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12015
gene id: 526227:MESIL_RS12015
uniprot id: D7BAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS01605
gene id: 526227:MESIL_RS01605
uniprot id: D7BHM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

526227:MESIL RS08420
gene id: 526227:MESIL_RS08420
uniprot id: D7BFK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS08400
gene id: 526227:MESIL_RS08400
uniprot id: D7BFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

526227:MESIL RS12720
gene id: 526227:MESIL_RS12720
uniprot id: D7BB12
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

526227:MESIL RS13280
gene id: 526227:MESIL_RS13280
uniprot id: D7BBN6
names: Similarity
messages: Belongs to the CFA/CMAS family.

526227:MESIL RS14170
gene id: 526227:MESIL_RS14170
uniprot id: D7BCS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

526227:MESIL RS16620
gene id: 526227:MESIL_RS16620
uniprot id: D7BIW1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS05380
gene id: 526227:MESIL_RS05380
uniprot id: D7BD49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

526227:MESIL RS13825
gene id: 526227:MESIL_RS13825
uniprot id: D7BC98
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

526227:MESIL RS10225
gene id: 526227:MESIL_RS10225
uniprot id: D7BH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS07175
gene id: 526227:MESIL_RS07175
uniprot id: D7BEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

526227:MESIL RS02310
gene id: 526227:MESIL_RS02310
uniprot id: D7B9V9
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS12350
gene id: 526227:MESIL_RS12350
uniprot id: D7BAT9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

526227:MESIL RS04820
gene id: 526227:MESIL_RS04820
uniprot id: D7BCH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS00065
gene id: 526227:MESIL_RS00065
uniprot id: D7BG39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS10000
gene id: 526227:MESIL_RS10000
uniprot id: D7BH09
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526227:MESIL RS14570
gene id: 526227:MESIL_RS14570
uniprot id: D7BD05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

526227:MESIL RS11560
gene id: 526227:MESIL_RS11560
uniprot id: D7BII5
names: Similarity
messages: Belongs to the SufE family.

526227:MESIL RS07085
gene id: 526227:MESIL_RS07085
uniprot id: D7BEU7
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS15110
gene id: 526227:MESIL_RS15110
uniprot id: D7BDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

526227:MESIL RS10135
gene id: 526227:MESIL_RS10135
uniprot id: D7BH33
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

526227:MESIL RS09280
gene id: 526227:MESIL_RS09280
uniprot id: D7BG20
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

526227:MESIL RS13865
gene id: 526227:MESIL_RS13865
uniprot id: D7BCA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS10765
gene id: 526227:MESIL_RS10765
uniprot id: D7BHS1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

526227:MESIL RS11110
gene id: 526227:MESIL_RS11110
uniprot id: D7BHY6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

526227:MESIL RS07310
gene id: 526227:MESIL_RS07310
uniprot id: D7BEZ1
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

526227:MESIL RS12910
gene id: 526227:MESIL_RS12910
uniprot id: D7BBG1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

526227:MESIL RS00590
gene id: 526227:MESIL_RS00590
uniprot id: D7BGQ6
names: Similarity
messages: Belongs to the peptidase M29 family.

526227:MESIL RS14810
gene id: 526227:MESIL_RS14810
uniprot id: D7BDG4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

526227:MESIL RS16580
gene id: 526227:MESIL_RS16580
uniprot id: D7BIV2
names: Similarity
messages: Belongs to the leucine-binding protein family.

526227:MESIL RS14490
gene id: 526227:MESIL_RS14490
uniprot id: D7BCY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

526227:MESIL RS16590
gene id: 526227:MESIL_RS16590
uniprot id: D7BIV4
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS09370
gene id: 526227:MESIL_RS09370
uniprot id: D7BGC2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

526227:MESIL RS12695
gene id: 526227:MESIL_RS12695
uniprot id: D7BB07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS07330
gene id: 526227:MESIL_RS07330
uniprot id: D7BEZ5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

526227:MESIL RS03950
gene id: 526227:MESIL_RS03950
uniprot id: D7BBC8
names: Similarity
messages: Belongs to the fructosamine kinase family.

526227:MESIL RS11105
gene id: 526227:MESIL_RS11105
uniprot id: D7BHY5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526227:MESIL RS13225
gene id: 526227:MESIL_RS13225
uniprot id: D7BBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

526227:MESIL RS03870
gene id: 526227:MESIL_RS03870
uniprot id: D7BBB2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

526227:MESIL RS02275
gene id: 526227:MESIL_RS02275
uniprot id: D7B9V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526227:MESIL RS10165
gene id: 526227:MESIL_RS10165
uniprot id: D7BH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

526227:MESIL RS05225
gene id: 526227:MESIL_RS05225
uniprot id: D7BCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

526227:MESIL RS11170
gene id: 526227:MESIL_RS11170
uniprot id: D7BIB3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS02395
gene id: 526227:MESIL_RS02395
uniprot id: D7B9X1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS17805
gene id: 526227:MESIL_RS17805
uniprot id: D7BJI0
names: Similarity
messages: Belongs to the RNase H family.

526227:MESIL RS10945
gene id: 526227:MESIL_RS10945
uniprot id: D7BHV6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

526227:MESIL RS12245
gene id: 526227:MESIL_RS12245
uniprot id: D7BAF7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

526227:MESIL RS09195
gene id: 526227:MESIL_RS09195
uniprot id: D7BG02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

526227:MESIL RS08005
gene id: 526227:MESIL_RS08005
uniprot id: D7BFC6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

526227:MESIL RS01165
gene id: 526227:MESIL_RS01165
uniprot id: D7BHD5
names: Similarity
messages: Belongs to the GSP E family.

526227:MESIL RS00790
gene id: 526227:MESIL_RS00790
uniprot id: D7BGU6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526227:MESIL RS13480
gene id: 526227:MESIL_RS13480
uniprot id: D7BC37
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

526227:MESIL RS11145
gene id: 526227:MESIL_RS11145
uniprot id: D7BIA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

526227:MESIL RS11295
gene id: 526227:MESIL_RS11295
uniprot id: D7BID8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

526227:MESIL RS07665
gene id: 526227:MESIL_RS07665
uniprot id: D7BF62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

526227:MESIL RS10050
gene id: 526227:MESIL_RS10050
uniprot id: D7BH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

526227:MESIL RS12860
gene id: 526227:MESIL_RS12860
uniprot id: D7BBF2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

526227:MESIL RS16360
gene id: 526227:MESIL_RS16360
uniprot id: D7BIQ9
names: Similarity
messages: Belongs to the ComB family.

526227:MESIL RS05980
gene id: 526227:MESIL_RS05980
uniprot id: D7BDS7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

526227:MESIL RS12845
gene id: 526227:MESIL_RS12845
uniprot id: D7BB37
names: Similarity
messages: Belongs to the fabD family.

526227:MESIL RS00355
gene id: 526227:MESIL_RS00355
uniprot id: D7BG96
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

526227:MESIL RS14340
gene id: 526227:MESIL_RS14340
uniprot id: D7BCW1
names: Subcellular Location Annotation
messages: Membrane

526227:MESIL RS01785
gene id: 526227:MESIL_RS01785
uniprot id: D7BI18
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

526227:MESIL RS07190
gene id: 526227:MESIL_RS07190
uniprot id: D7BEW7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

526227:MESIL RS00645
gene id: 526227:MESIL_RS00645
uniprot id: D7BGR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526227:MESIL RS04190
gene id: 526227:MESIL_RS04190
uniprot id: D7BBT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526227:MESIL RS05095
gene id: 526227:MESIL_RS05095
uniprot id: D7BCM9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

526227:MESIL RS13120
gene id: 526227:MESIL_RS13120
uniprot id: D7BBK2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

526227:MESIL RS01205
gene id: 526227:MESIL_RS01205
uniprot id: D7BHE3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

526227:MESIL RS03255
gene id: 526227:MESIL_RS03255
uniprot id: D7BAN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

526227:MESIL RS12450
gene id: 526227:MESIL_RS12450
uniprot id: D7BAW0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

526227:MESIL RS18060
gene id: 526227:MESIL_RS18060
uniprot id: D7BJN1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

526227:MESIL RS07850
gene id: 526227:MESIL_RS07850
uniprot id: D7BF99
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

526227:MESIL RS13315
gene id: 526227:MESIL_RS13315
uniprot id: D7BBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS16005
gene id: 526227:MESIL_RS16005
uniprot id: D7BEQ7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

526227:MESIL RS11455
gene id: 526227:MESIL_RS11455
uniprot id: D7BIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

526227:MESIL RS18005
gene id: 526227:MESIL_RS18005
uniprot id: D7BJM0
names: Similarity
messages: Belongs to the GSP E family.

526227:MESIL RS04795
gene id: 526227:MESIL_RS04795
uniprot id: D7BCH2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

526227:MESIL RS07220
gene id: 526227:MESIL_RS07220
uniprot id: D7BEX3
names: Similarity
messages: Belongs to the malate synthase family.

526227:MESIL RS04560
gene id: 526227:MESIL_RS04560
uniprot id: D7BC14
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526227:MESIL RS16675
gene id: 526227:MESIL_RS16675
uniprot id: D7BIX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

526227:MESIL RS13135
gene id: 526227:MESIL_RS13135
uniprot id: D7BBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

526227:MESIL RS18825
gene id: 526227:MESIL_RS18825
uniprot id: D7BJI1
names: Similarity
messages: Belongs to the ParB family.

526227:MESIL RS00215
gene id: 526227:MESIL_RS00215
uniprot id: D7BG68
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

526227:MESIL RS01920
gene id: 526227:MESIL_RS01920
uniprot id: D7BI44
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

526227:MESIL RS06325
gene id: 526227:MESIL_RS06325
uniprot id: D7BDZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

526227:MESIL RS13185
gene id: 526227:MESIL_RS13185
uniprot id: D7BBL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS10495
gene id: 526227:MESIL_RS10495
uniprot id: D7BHA5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

526227:MESIL RS16610
gene id: 526227:MESIL_RS16610
uniprot id: D7BIV8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526227:MESIL RS03510
gene id: 526227:MESIL_RS03510
uniprot id: D7BB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS07555
gene id: 526227:MESIL_RS07555
uniprot id: D7BF41
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

526227:MESIL RS03820
gene id: 526227:MESIL_RS03820
uniprot id: D7BBA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

526227:MESIL RS06850
gene id: 526227:MESIL_RS06850
uniprot id: D7BEL1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

526227:MESIL RS13490
gene id: 526227:MESIL_RS13490
uniprot id: D7BC39
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

526227:MESIL RS00305
gene id: 526227:MESIL_RS00305
uniprot id: D7BG86
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526227:MESIL RS04480
gene id: 526227:MESIL_RS04480
uniprot id: D7BBZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

526227:MESIL RS10465
gene id: 526227:MESIL_RS10465
uniprot id: D7BHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

526227:MESIL RS08660
gene id: 526227:MESIL_RS08660
uniprot id: D7BFQ0
names: Similarity
messages: Belongs to the RecO family.

526227:MESIL RS17540
gene id: 526227:MESIL_RS17540
uniprot id: D7BJD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

526227:MESIL RS15215
gene id: 526227:MESIL_RS15215
uniprot id: D7BDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

526227:MESIL RS01685
gene id: 526227:MESIL_RS01685
uniprot id: D7BHZ8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

526227:MESIL RS11965
gene id: 526227:MESIL_RS11965
uniprot id: D7BAA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

526227:MESIL RS12060
gene id: 526227:MESIL_RS12060
uniprot id: D7BAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS03515
gene id: 526227:MESIL_RS03515
uniprot id: D7BB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS13840
gene id: 526227:MESIL_RS13840
uniprot id: D7BCA1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

526227:MESIL RS15660
gene id: 526227:MESIL_RS15660
uniprot id: D7BE83
names: Similarity
messages: Belongs to the RutC family.

526227:MESIL RS14180
gene id: 526227:MESIL_RS14180
uniprot id: D7BCT0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

526227:MESIL RS00795
gene id: 526227:MESIL_RS00795
uniprot id: D7BGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526227:MESIL RS03460
gene id: 526227:MESIL_RS03460
uniprot id: D7BAS5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

526227:MESIL RS07425
gene id: 526227:MESIL_RS07425
uniprot id: D7BF15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

526227:MESIL RS06445
gene id: 526227:MESIL_RS06445
uniprot id: D7BED0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

526227:MESIL RS07620
gene id: 526227:MESIL_RS07620
uniprot id: D7BF53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526227:MESIL RS04245
gene id: 526227:MESIL_RS04245
uniprot id: D7BBV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

526227:MESIL RS15465
gene id: 526227:MESIL_RS15465
uniprot id: D7BE49
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

526227:MESIL RS03370
gene id: 526227:MESIL_RS03370
uniprot id: D7BAR0
names: Biotechnology
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Glucosylglycerate phosphorylase subfamily.
messages: Catalyzes the reversible phosphorolysis of glucosylglycerate into alpha-D-glucose 1-phosphate (Glc1P) and D-glycerate. May be a regulator of intracellular levels of glucosylglycerate, a compatible solute that primarily protects organisms facing salt stress and very specific nutritional constraints. Has a very strict substrate specificity. Cannot catalyze the phosphorolysis of sucrose or synthesize sucrose from Glc1P and D-fructose.
messages: The excellent specific activity of this enzyme towards glycerate opens up new options for the commercial production of glucosylglycerate. This compound has been reported to be an exceptionally potent and versatile stabilizer of proteins at elevated temperatures.

526227:MESIL RS17560
gene id: 526227:MESIL_RS17560
uniprot id: D7BJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

526227:MESIL RS04140
gene id: 526227:MESIL_RS04140
uniprot id: D7BBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

526227:MESIL RS05870
gene id: 526227:MESIL_RS05870
uniprot id: D7BDQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

526227:MESIL RS08140
gene id: 526227:MESIL_RS08140
uniprot id: D7BFF1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Cytoplasm
messages: Homodimer.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.