526225:GOBS RS21995
gene id: 526225:GOBS_RS21995
uniprot id: D2SH90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

526225:GOBS RS03275
gene id: 526225:GOBS_RS03275
uniprot id: D2S7D2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS10885
gene id: 526225:GOBS_RS10885
uniprot id: D2SGR5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS19160
gene id: 526225:GOBS_RS19160
uniprot id: D2SDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS25725
gene id: 526225:GOBS_RS25725
uniprot id: D2SD97
names: Similarity
messages: Belongs to the peptidase S14 family.

526225:GOBS RS10720
gene id: 526225:GOBS_RS10720
uniprot id: D2SFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

526225:GOBS RS06705
gene id: 526225:GOBS_RS06705
uniprot id: D2SBF0
names: Similarity
messages: Belongs to the UPF0047 family.

526225:GOBS RS16500
gene id: 526225:GOBS_RS16500
uniprot id: D2SAT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS04960
gene id: 526225:GOBS_RS04960
uniprot id: D2S9P7
names: Similarity
messages: Belongs to the citrate synthase family.

526225:GOBS RS24980
gene id: 526225:GOBS_RS24980
uniprot id: D2S842
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

526225:GOBS RS23775
gene id: 526225:GOBS_RS23775
uniprot id: D2S5Y0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

526225:GOBS RS00485
gene id: 526225:GOBS_RS00485
uniprot id: D2SGM3
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

526225:GOBS RS20080
gene id: 526225:GOBS_RS20080
uniprot id: D2SEN9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526225:GOBS RS20135
gene id: 526225:GOBS_RS20135
uniprot id: D2SEP9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS09130
gene id: 526225:GOBS_RS09130
uniprot id: D2S558
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526225:GOBS RS00010
gene id: 526225:GOBS_RS00010
uniprot id: D2SFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

526225:GOBS RS08630
gene id: 526225:GOBS_RS08630
uniprot id: D2SDL1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS01210
gene id: 526225:GOBS_RS01210
uniprot id: D2S421
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

526225:GOBS RS23290
gene id: 526225:GOBS_RS23290
uniprot id: D2S5N7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

526225:GOBS RS22300
gene id: 526225:GOBS_RS22300
uniprot id: D2SHE9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

526225:GOBS RS02700
gene id: 526225:GOBS_RS02700
uniprot id: D2S6A2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

526225:GOBS RS24705
gene id: 526225:GOBS_RS24705
uniprot id: D2S7Y8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS16450
gene id: 526225:GOBS_RS16450
uniprot id: D2SAS4
names: Similarity
messages: Belongs to the GcvT family.

526225:GOBS RS14790
gene id: 526225:GOBS_RS14790
uniprot id: D2S8Q6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

526225:GOBS RS02815
gene id: 526225:GOBS_RS02815
uniprot id: D2S743
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

526225:GOBS RS24560
gene id: 526225:GOBS_RS24560
uniprot id: D2S7V9
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

526225:GOBS RS16325
gene id: 526225:GOBS_RS16325
uniprot id: D2SAC0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

526225:GOBS RS18565
gene id: 526225:GOBS_RS18565
uniprot id: D2SD36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS01370
gene id: 526225:GOBS_RS01370
uniprot id: D2S4X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

526225:GOBS RS24360
gene id: 526225:GOBS_RS24360
uniprot id: D2S708
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

526225:GOBS RS23400
gene id: 526225:GOBS_RS23400
uniprot id: D2S5R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

526225:GOBS RS09330
gene id: 526225:GOBS_RS09330
uniprot id: D2SED0
names: Similarity
messages: Belongs to the YciI family.

526225:GOBS RS01470
gene id: 526225:GOBS_RS01470
uniprot id: D2S4Y9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

526225:GOBS RS24040
gene id: 526225:GOBS_RS24040
uniprot id: D2S6U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

526225:GOBS RS12480
gene id: 526225:GOBS_RS12480
uniprot id: D2S5D3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS11875
gene id: 526225:GOBS_RS11875
uniprot id: D2S4A8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS23680
gene id: 526225:GOBS_RS23680
uniprot id: D2S5W2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS11220
gene id: 526225:GOBS_RS11220
uniprot id: D2SGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS17400
gene id: 526225:GOBS_RS17400
uniprot id: D2SBN9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

526225:GOBS RS08190
gene id: 526225:GOBS_RS08190
uniprot id: D2SCZ1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS05405
gene id: 526225:GOBS_RS05405
uniprot id: D2S9Y3
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

526225:GOBS RS15400
gene id: 526225:GOBS_RS15400
uniprot id: D2S9F7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS14780
gene id: 526225:GOBS_RS14780
uniprot id: D2S8Q4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

526225:GOBS RS09030
gene id: 526225:GOBS_RS09030
uniprot id: D2SE70
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526225:GOBS RS25405
gene id: 526225:GOBS_RS25405
uniprot id: D2SH05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

526225:GOBS RS13900
gene id: 526225:GOBS_RS13900
uniprot id: D2S7L2
names: Similarity
messages: Belongs to the hyi family.

526225:GOBS RS15465
gene id: 526225:GOBS_RS15465
uniprot id: D2S9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS14770
gene id: 526225:GOBS_RS14770
uniprot id: D2S8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

526225:GOBS RS07020
gene id: 526225:GOBS_RS07020
uniprot id: D2SBY9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS07795
gene id: 526225:GOBS_RS07795
uniprot id: D2SCR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS01730
gene id: 526225:GOBS_RS01730
uniprot id: D2S531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

526225:GOBS RS20365
gene id: 526225:GOBS_RS20365
uniprot id: D2SEU3
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS23860
gene id: 526225:GOBS_RS23860
uniprot id: D2S6R0
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS02930
gene id: 526225:GOBS_RS02930
uniprot id: D2S767
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

526225:GOBS RS23890
gene id: 526225:GOBS_RS23890
uniprot id: D2S6R5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15520
gene id: 526225:GOBS_RS15520
uniprot id: D2S9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

526225:GOBS RS01215
gene id: 526225:GOBS_RS01215
uniprot id: D2S422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

526225:GOBS RS14880
gene id: 526225:GOBS_RS14880
uniprot id: D2S8S5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS12495
gene id: 526225:GOBS_RS12495
uniprot id: D2S5D7
names: Similarity
messages: Belongs to the MEMO1 family.

526225:GOBS RS16235
gene id: 526225:GOBS_RS16235
uniprot id: D2SAA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS04540
gene id: 526225:GOBS_RS04540
uniprot id: D2S933
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

526225:GOBS RS03175
gene id: 526225:GOBS_RS03175
uniprot id: D2S7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

526225:GOBS RS04775
gene id: 526225:GOBS_RS04775
uniprot id: D2S980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

526225:GOBS RS10035
gene id: 526225:GOBS_RS10035
uniprot id: D2SF49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

526225:GOBS RS20575
gene id: 526225:GOBS_RS20575
uniprot id: D2SFB8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526225:GOBS RS22085
gene id: 526225:GOBS_RS22085
uniprot id: D2SHA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

526225:GOBS RS08530
gene id: 526225:GOBS_RS08530
uniprot id: D2SDJ1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21720
gene id: 526225:GOBS_RS21720
uniprot id: D2SGC2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21840
gene id: 526225:GOBS_RS21840
uniprot id: D2SH59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS06625
gene id: 526225:GOBS_RS06625
uniprot id: D2SBD5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS26985
gene id: 526225:GOBS_RS26985
uniprot id: D2S406
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

526225:GOBS RS07250
gene id: 526225:GOBS_RS07250
uniprot id: D2SC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

526225:GOBS RS17210
gene id: 526225:GOBS_RS17210
uniprot id: D2SBK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

526225:GOBS RS02495
gene id: 526225:GOBS_RS02495
uniprot id: D2S662
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS06715
gene id: 526225:GOBS_RS06715
uniprot id: D2SBF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

526225:GOBS RS18295
gene id: 526225:GOBS_RS18295
uniprot id: D2SCK3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526225:GOBS RS04770
gene id: 526225:GOBS_RS04770
uniprot id: D2S979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

526225:GOBS RS19095
gene id: 526225:GOBS_RS19095
uniprot id: D2SDS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS02390
gene id: 526225:GOBS_RS02390
uniprot id: D2S641
names: Similarity
messages: Belongs to the AHA1 family.

526225:GOBS RS07820
gene id: 526225:GOBS_RS07820
uniprot id: D2SCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

526225:GOBS RS10725
gene id: 526225:GOBS_RS10725
uniprot id: D2SFX0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS19950
gene id: 526225:GOBS_RS19950
uniprot id: D2SEL3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

526225:GOBS RS06515
gene id: 526225:GOBS_RS06515
uniprot id: D2SBB2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS04570
gene id: 526225:GOBS_RS04570
uniprot id: D2S939
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

526225:GOBS RS23370
gene id: 526225:GOBS_RS23370
uniprot id: D2S5Q4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

526225:GOBS RS14765
gene id: 526225:GOBS_RS14765
uniprot id: D2S8Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

526225:GOBS RS03365
gene id: 526225:GOBS_RS03365
uniprot id: D2S7E8
names: Similarity
messages: Belongs to the GSP E family.

526225:GOBS RS21365
gene id: 526225:GOBS_RS21365
uniprot id: D2SG54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

526225:GOBS RS15755
gene id: 526225:GOBS_RS15755
uniprot id: D2SA06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

526225:GOBS RS13550
gene id: 526225:GOBS_RS13550
uniprot id: D2S6M7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16970
gene id: 526225:GOBS_RS16970
uniprot id: D2SB26
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

526225:GOBS RS00120
gene id: 526225:GOBS_RS00120
uniprot id: D2SGF2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10930
gene id: 526225:GOBS_RS10930
uniprot id: D2SGS4
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

526225:GOBS RS13590
gene id: 526225:GOBS_RS13590
uniprot id: D2S6N5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526225:GOBS RS15915
gene id: 526225:GOBS_RS15915
uniprot id: D2SA38
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

526225:GOBS RS19405
gene id: 526225:GOBS_RS19405
uniprot id: D2SDY0
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS04440
gene id: 526225:GOBS_RS04440
uniprot id: D2S914
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS02710
gene id: 526225:GOBS_RS02710
uniprot id: D2S6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

526225:GOBS RS18385
gene id: 526225:GOBS_RS18385
uniprot id: D2SD00
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS12930
gene id: 526225:GOBS_RS12930
uniprot id: D2S5K3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS19275
gene id: 526225:GOBS_RS19275
uniprot id: D2SDV4
names: Similarity
messages: Belongs to the peptidase M16 family.

526225:GOBS RS11880
gene id: 526225:GOBS_RS11880
uniprot id: D2S4A9
names: Similarity
messages: Belongs to the YciI family.

526225:GOBS RS04140
gene id: 526225:GOBS_RS04140
uniprot id: D2S8V5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

526225:GOBS RS23545
gene id: 526225:GOBS_RS23545
uniprot id: D2S5T8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

526225:GOBS RS15325
gene id: 526225:GOBS_RS15325
uniprot id: D2S9E2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

526225:GOBS RS19070
gene id: 526225:GOBS_RS19070
uniprot id: D2SDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS05590
gene id: 526225:GOBS_RS05590
uniprot id: D2SAF5
names: Similarity
messages: Belongs to the peptidase S1C family.

526225:GOBS RS02085
gene id: 526225:GOBS_RS02085
uniprot id: D2S5Y9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

526225:GOBS RS20510
gene id: 526225:GOBS_RS20510
uniprot id: D2SFA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526225:GOBS RS03890
gene id: 526225:GOBS_RS03890
uniprot id: D2S8C5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS06680
gene id: 526225:GOBS_RS06680
uniprot id: D2SBE5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

526225:GOBS RS24640
gene id: 526225:GOBS_RS24640
uniprot id: D2S7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526225:GOBS RS22550
gene id: 526225:GOBS_RS22550
uniprot id: D2S4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

526225:GOBS RS20430
gene id: 526225:GOBS_RS20430
uniprot id: D2SF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

526225:GOBS RS07545
gene id: 526225:GOBS_RS07545
uniprot id: D2SCM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526225:GOBS RS16215
gene id: 526225:GOBS_RS16215
uniprot id: D2SA98
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

526225:GOBS RS09485
gene id: 526225:GOBS_RS09485
uniprot id: D2SEG1
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

526225:GOBS RS09845
gene id: 526225:GOBS_RS09845
uniprot id: D2SF11
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

526225:GOBS RS22770
gene id: 526225:GOBS_RS22770
uniprot id: D2S4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

526225:GOBS RS11255
gene id: 526225:GOBS_RS11255
uniprot id: D2SGY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526225:GOBS RS10630
gene id: 526225:GOBS_RS10630
uniprot id: D2SFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

526225:GOBS RS15880
gene id: 526225:GOBS_RS15880
uniprot id: D2SA31
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

526225:GOBS RS21990
gene id: 526225:GOBS_RS21990
uniprot id: D2SH89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

526225:GOBS RS19550
gene id: 526225:GOBS_RS19550
uniprot id: D2SE08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

526225:GOBS RS04870
gene id: 526225:GOBS_RS04870
uniprot id: D2S9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

526225:GOBS RS11465
gene id: 526225:GOBS_RS11465
uniprot id: D2SH26
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14250
gene id: 526225:GOBS_RS14250
uniprot id: D2S7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

526225:GOBS RS21005
gene id: 526225:GOBS_RS21005
uniprot id: D2SFK5
names: Similarity
messages: Belongs to the UPF0434 family.

526225:GOBS RS22060
gene id: 526225:GOBS_RS22060
uniprot id: D2SHA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

526225:GOBS RS12335
gene id: 526225:GOBS_RS12335
uniprot id: D2S5B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

526225:GOBS RS18675
gene id: 526225:GOBS_RS18675
uniprot id: D2SD58
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

526225:GOBS RS00450
gene id: 526225:GOBS_RS00450
uniprot id: D2SGL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

526225:GOBS RS19585
gene id: 526225:GOBS_RS19585
uniprot id: D2SE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS08990
gene id: 526225:GOBS_RS08990
uniprot id: D2SE62
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

526225:GOBS RS10385
gene id: 526225:GOBS_RS10385
uniprot id: D2SFQ4
names: Similarity
messages: Belongs to the Fur family.

526225:GOBS RS13845
gene id: 526225:GOBS_RS13845
uniprot id: D2S7K1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

526225:GOBS RS04130
gene id: 526225:GOBS_RS04130
uniprot id: D2S8V3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS00955
gene id: 526225:GOBS_RS00955
uniprot id: D2S3X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

526225:GOBS RS20215
gene id: 526225:GOBS_RS20215
uniprot id: D2SER5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

526225:GOBS RS00880
gene id: 526225:GOBS_RS00880
uniprot id: D2S3V9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Homotetramer.
messages: Inhibited by cyanuric acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer and the active site possess nearly threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads, but one of the 3 active site surfaces varies in composition suggesting it is involved in confering substrate specificity.

526225:GOBS RS03085
gene id: 526225:GOBS_RS03085
uniprot id: D2S796
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS07860
gene id: 526225:GOBS_RS07860
uniprot id: D2SCS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

526225:GOBS RS14465
gene id: 526225:GOBS_RS14465
uniprot id: D2S8J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

526225:GOBS RS14945
gene id: 526225:GOBS_RS14945
uniprot id: D2S8T8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

526225:GOBS RS17160
gene id: 526225:GOBS_RS17160
uniprot id: D2SBJ4
names: Similarity
messages: Belongs to the CdaR family.

526225:GOBS RS11475
gene id: 526225:GOBS_RS11475
uniprot id: D2SH28
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

526225:GOBS RS04835
gene id: 526225:GOBS_RS04835
uniprot id: D2S9M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS22255
gene id: 526225:GOBS_RS22255
uniprot id: D2SHE0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

526225:GOBS RS20025
gene id: 526225:GOBS_RS20025
uniprot id: D2SEM8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

526225:GOBS RS22440
gene id: 526225:GOBS_RS22440
uniprot id: D2SHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

526225:GOBS RS11130
gene id: 526225:GOBS_RS11130
uniprot id: D2SGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

526225:GOBS RS03270
gene id: 526225:GOBS_RS03270
uniprot id: D2S7D1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS11480
gene id: 526225:GOBS_RS11480
uniprot id: D2SH29
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

526225:GOBS RS15960
gene id: 526225:GOBS_RS15960
uniprot id: D2SA47
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

526225:GOBS RS08495
gene id: 526225:GOBS_RS08495
uniprot id: D2SDI4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526225:GOBS RS21825
gene id: 526225:GOBS_RS21825
uniprot id: D2SH56
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

526225:GOBS RS00950
gene id: 526225:GOBS_RS00950
uniprot id: D2S3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

526225:GOBS RS24825
gene id: 526225:GOBS_RS24825
uniprot id: D2S812
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

526225:GOBS RS10285
gene id: 526225:GOBS_RS10285
uniprot id: D2SFN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

526225:GOBS RS16475
gene id: 526225:GOBS_RS16475
uniprot id: D2SAS9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

526225:GOBS RS10250
gene id: 526225:GOBS_RS10250
uniprot id: D2SFM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS08600
gene id: 526225:GOBS_RS08600
uniprot id: D2SDK5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS00865
gene id: 526225:GOBS_RS00865
uniprot id: D2S3V5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

526225:GOBS RS14030
gene id: 526225:GOBS_RS14030
uniprot id: D2S7N8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

526225:GOBS RS05255
gene id: 526225:GOBS_RS05255
uniprot id: D2S9V3
names: Similarity
messages: Belongs to the peptidase M1 family.

526225:GOBS RS21105
gene id: 526225:GOBS_RS21105
uniprot id: D2SG10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS24080
gene id: 526225:GOBS_RS24080
uniprot id: D2S6V2
names: Similarity
messages: Belongs to the peptidase U62 family.

526225:GOBS RS16660
gene id: 526225:GOBS_RS16660
uniprot id: D2SAW6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

526225:GOBS RS01170
gene id: 526225:GOBS_RS01170
uniprot id: D2S413
names: Similarity
messages: Belongs to the cytochrome P450 family.

526225:GOBS RS16940
gene id: 526225:GOBS_RS16940
uniprot id: D2SB20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS06600
gene id: 526225:GOBS_RS06600
uniprot id: D2SBD0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS06235
gene id: 526225:GOBS_RS06235
uniprot id: D2SB61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS21505
gene id: 526225:GOBS_RS21505
uniprot id: D2SG82
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

526225:GOBS RS11165
gene id: 526225:GOBS_RS11165
uniprot id: D2SGW9
names: Similarity
messages: Belongs to the YciI family.

526225:GOBS RS11410
gene id: 526225:GOBS_RS11410
uniprot id: D2SH16
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

526225:GOBS RS15310
gene id: 526225:GOBS_RS15310
uniprot id: D2S9D8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS21675
gene id: 526225:GOBS_RS21675
uniprot id: D2SGB6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

526225:GOBS RS14080
gene id: 526225:GOBS_RS14080
uniprot id: D2S7P7
names: Similarity
messages: Belongs to the GcvT family.

526225:GOBS RS15190
gene id: 526225:GOBS_RS15190
uniprot id: D2S9B5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

526225:GOBS RS15730
gene id: 526225:GOBS_RS15730
uniprot id: D2SA01
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

526225:GOBS RS06295
gene id: 526225:GOBS_RS06295
uniprot id: D2SB73
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

526225:GOBS RS05170
gene id: 526225:GOBS_RS05170
uniprot id: D2S9T7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526225:GOBS RS13270
gene id: 526225:GOBS_RS13270
uniprot id: D2S6H5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

526225:GOBS RS18995
gene id: 526225:GOBS_RS18995
uniprot id: D2SDB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

526225:GOBS RS19485
gene id: 526225:GOBS_RS19485
uniprot id: D2SDZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

526225:GOBS RS22275
gene id: 526225:GOBS_RS22275
uniprot id: D2SHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS22045
gene id: 526225:GOBS_RS22045
uniprot id: D2SHA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

526225:GOBS RS14450
gene id: 526225:GOBS_RS14450
uniprot id: D2S8J4
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15670
gene id: 526225:GOBS_RS15670
uniprot id: D2S9K6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

526225:GOBS RS12565
gene id: 526225:GOBS_RS12565
uniprot id: D2S5E8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

526225:GOBS RS07885
gene id: 526225:GOBS_RS07885
uniprot id: D2SCT1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526225:GOBS RS14340
gene id: 526225:GOBS_RS14340
uniprot id: D2S7U5
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS07670
gene id: 526225:GOBS_RS07670
uniprot id: D2SCP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS03185
gene id: 526225:GOBS_RS03185
uniprot id: D2S7B4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS22155
gene id: 526225:GOBS_RS22155
uniprot id: D2SHC3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

526225:GOBS RS19890
gene id: 526225:GOBS_RS19890
uniprot id: D2SEK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

526225:GOBS RS13935
gene id: 526225:GOBS_RS13935
uniprot id: D2S7L8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

526225:GOBS RS16275
gene id: 526225:GOBS_RS16275
uniprot id: D2SAB1
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

526225:GOBS RS08485
gene id: 526225:GOBS_RS08485
uniprot id: D2SDI2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS06255
gene id: 526225:GOBS_RS06255
uniprot id: D2SB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS19860
gene id: 526225:GOBS_RS19860
uniprot id: D2SEJ5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

526225:GOBS RS20605
gene id: 526225:GOBS_RS20605
uniprot id: D2SFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS07035
gene id: 526225:GOBS_RS07035
uniprot id: D2SBZ2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10175
gene id: 526225:GOBS_RS10175
uniprot id: D2SF78
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

526225:GOBS RS13525
gene id: 526225:GOBS_RS13525
uniprot id: D2S6M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

526225:GOBS RS21775
gene id: 526225:GOBS_RS21775
uniprot id: D2SGD2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

526225:GOBS RS09375
gene id: 526225:GOBS_RS09375
uniprot id: D2SED9
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

526225:GOBS RS22125
gene id: 526225:GOBS_RS22125
uniprot id: D2SHB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

526225:GOBS RS01610
gene id: 526225:GOBS_RS01610
uniprot id: D2S512
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS20145
gene id: 526225:GOBS_RS20145
uniprot id: D2SEQ1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526225:GOBS RS23895
gene id: 526225:GOBS_RS23895
uniprot id: D2S6R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS06620
gene id: 526225:GOBS_RS06620
uniprot id: D2SBD4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

526225:GOBS RS17150
gene id: 526225:GOBS_RS17150
uniprot id: D2SBJ2
names: Similarity
messages: Belongs to the pirin family.

526225:GOBS RS02875
gene id: 526225:GOBS_RS02875
uniprot id: D2S755
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526225:GOBS RS07560
gene id: 526225:GOBS_RS07560
uniprot id: D2SCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

526225:GOBS RS15270
gene id: 526225:GOBS_RS15270
uniprot id: D2S9D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

526225:GOBS RS21325
gene id: 526225:GOBS_RS21325
uniprot id: D2SG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

526225:GOBS RS04055
gene id: 526225:GOBS_RS04055
uniprot id: D2S8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

526225:GOBS RS01605
gene id: 526225:GOBS_RS01605
uniprot id: D2S511
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526225:GOBS RS04380
gene id: 526225:GOBS_RS04380
uniprot id: D2S903
names: Similarity
messages: Belongs to the UDPGP type 2 family.

526225:GOBS RS04450
gene id: 526225:GOBS_RS04450
uniprot id: D2S916
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

526225:GOBS RS11055
gene id: 526225:GOBS_RS11055
uniprot id: D2SGU7
names: Subcellular Location Annotation
messages: Cytoplasm

526225:GOBS RS09490
gene id: 526225:GOBS_RS09490
uniprot id: D2SEG2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

526225:GOBS RS11890
gene id: 526225:GOBS_RS11890
uniprot id: D2S4B1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19775
gene id: 526225:GOBS_RS19775
uniprot id: D2SEI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526225:GOBS RS11050
gene id: 526225:GOBS_RS11050
uniprot id: D2SGU6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10075
gene id: 526225:GOBS_RS10075
uniprot id: D2SF59
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS06635
gene id: 526225:GOBS_RS06635
uniprot id: D2SBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

526225:GOBS RS09250
gene id: 526225:GOBS_RS09250
uniprot id: D2SEB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

526225:GOBS RS28950
gene id: 526225:GOBS_RS28950
uniprot id: D2SCG9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526225:GOBS RS24970
gene id: 526225:GOBS_RS24970
uniprot id: D2S840
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

526225:GOBS RS24055
gene id: 526225:GOBS_RS24055
uniprot id: D2S6U7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22410
gene id: 526225:GOBS_RS22410
uniprot id: D2SHH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS06020
gene id: 526225:GOBS_RS06020
uniprot id: D2SAP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS28235
gene id: 526225:GOBS_RS28235
uniprot id: D2S8T6
names: Similarity
messages: Belongs to the YciI family.

526225:GOBS RS16495
gene id: 526225:GOBS_RS16495
uniprot id: D2SAT3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

526225:GOBS RS11385
gene id: 526225:GOBS_RS11385
uniprot id: D2SH13
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS00165
gene id: 526225:GOBS_RS00165
uniprot id: D2SGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

526225:GOBS RS14560
gene id: 526225:GOBS_RS14560
uniprot id: D2S8L4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS08810
gene id: 526225:GOBS_RS08810
uniprot id: D2SDP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

526225:GOBS RS02715
gene id: 526225:GOBS_RS02715
uniprot id: D2S6A5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS12000
gene id: 526225:GOBS_RS12000
uniprot id: D2S4D4
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

526225:GOBS RS02385
gene id: 526225:GOBS_RS02385
uniprot id: D2S640
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

526225:GOBS RS15475
gene id: 526225:GOBS_RS15475
uniprot id: D2S9H2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS15515
gene id: 526225:GOBS_RS15515
uniprot id: D2S9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

526225:GOBS RS14395
gene id: 526225:GOBS_RS14395
uniprot id: D2S8I3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS13945
gene id: 526225:GOBS_RS13945
uniprot id: D2S7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

526225:GOBS RS19695
gene id: 526225:GOBS_RS19695
uniprot id: D2SE36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

526225:GOBS RS24520
gene id: 526225:GOBS_RS24520
uniprot id: D2S7V1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

526225:GOBS RS04965
gene id: 526225:GOBS_RS04965
uniprot id: D2S9P8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

526225:GOBS RS22280
gene id: 526225:GOBS_RS22280
uniprot id: D2SHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS02830
gene id: 526225:GOBS_RS02830
uniprot id: D2S746
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

526225:GOBS RS19510
gene id: 526225:GOBS_RS19510
uniprot id: D2SE00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

526225:GOBS RS21220
gene id: 526225:GOBS_RS21220
uniprot id: D2SG32
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

526225:GOBS RS22670
gene id: 526225:GOBS_RS22670
uniprot id: D2S4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurD2 subfamily.
messages: Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

526225:GOBS RS11995
gene id: 526225:GOBS_RS11995
uniprot id: D2S4D2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

526225:GOBS RS02405
gene id: 526225:GOBS_RS02405
uniprot id: D2S644
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

526225:GOBS RS16030
gene id: 526225:GOBS_RS16030
uniprot id: D2SA61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

526225:GOBS RS15645
gene id: 526225:GOBS_RS15645
uniprot id: D2S9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

526225:GOBS RS22020
gene id: 526225:GOBS_RS22020
uniprot id: D2SH95
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

526225:GOBS RS08405
gene id: 526225:GOBS_RS08405
uniprot id: D2SDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS21930
gene id: 526225:GOBS_RS21930
uniprot id: D2SH77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

526225:GOBS RS20125
gene id: 526225:GOBS_RS20125
uniprot id: D2SEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

526225:GOBS RS19190
gene id: 526225:GOBS_RS19190
uniprot id: D2SDU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

526225:GOBS RS01005
gene id: 526225:GOBS_RS01005
uniprot id: D2S3Y1
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

526225:GOBS RS11735
gene id: 526225:GOBS_RS11735
uniprot id: D2S481
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19660
gene id: 526225:GOBS_RS19660
uniprot id: D2SE29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

526225:GOBS RS21870
gene id: 526225:GOBS_RS21870
uniprot id: D2SH65
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

526225:GOBS RS00935
gene id: 526225:GOBS_RS00935
uniprot id: D2S3W7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

526225:GOBS RS22350
gene id: 526225:GOBS_RS22350
uniprot id: D2SHF9
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

526225:GOBS RS11045
gene id: 526225:GOBS_RS11045
uniprot id: D2SGU5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11920
gene id: 526225:GOBS_RS11920
uniprot id: D2S4B7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

526225:GOBS RS08110
gene id: 526225:GOBS_RS08110
uniprot id: D2SCX5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

526225:GOBS RS19990
gene id: 526225:GOBS_RS19990
uniprot id: D2SEM1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

526225:GOBS RS19935
gene id: 526225:GOBS_RS19935
uniprot id: D2SEL0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

526225:GOBS RS22265
gene id: 526225:GOBS_RS22265
uniprot id: D2SHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

526225:GOBS RS20250
gene id: 526225:GOBS_RS20250
uniprot id: D2SES2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23565
gene id: 526225:GOBS_RS23565
uniprot id: D2S5U2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS03960
gene id: 526225:GOBS_RS03960
uniprot id: D2S8E0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526225:GOBS RS03370
gene id: 526225:GOBS_RS03370
uniprot id: D2S7E9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22775
gene id: 526225:GOBS_RS22775
uniprot id: D2S4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

526225:GOBS RS24715
gene id: 526225:GOBS_RS24715
uniprot id: D2S7Z0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS14545
gene id: 526225:GOBS_RS14545
uniprot id: D2S8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

526225:GOBS RS16595
gene id: 526225:GOBS_RS16595
uniprot id: D2SAV3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

526225:GOBS RS10105
gene id: 526225:GOBS_RS10105
uniprot id: D2SF65
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

526225:GOBS RS09335
gene id: 526225:GOBS_RS09335
uniprot id: D2SED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

526225:GOBS RS15450
gene id: 526225:GOBS_RS15450
uniprot id: D2S9G7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

526225:GOBS RS14295
gene id: 526225:GOBS_RS14295
uniprot id: D2S7T6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526225:GOBS RS01275
gene id: 526225:GOBS_RS01275
uniprot id: D2S434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS21055
gene id: 526225:GOBS_RS21055
uniprot id: D2SFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

526225:GOBS RS15150
gene id: 526225:GOBS_RS15150
uniprot id: D2S9A8
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS02265
gene id: 526225:GOBS_RS02265
uniprot id: D2S618
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

526225:GOBS RS21715
gene id: 526225:GOBS_RS21715
uniprot id: D2SGC1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19290
gene id: 526225:GOBS_RS19290
uniprot id: D2SDV7
names: Similarity
messages: Belongs to the ribF family.

526225:GOBS RS05660
gene id: 526225:GOBS_RS05660
uniprot id: D2SAG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS11740
gene id: 526225:GOBS_RS11740
uniprot id: D2S482
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

526225:GOBS RS19040
gene id: 526225:GOBS_RS19040
uniprot id: D2SDR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526225:GOBS RS13705
gene id: 526225:GOBS_RS13705
uniprot id: D2S7H3
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS03265
gene id: 526225:GOBS_RS03265
uniprot id: D2S7D0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

526225:GOBS RS11530
gene id: 526225:GOBS_RS11530
uniprot id: D2SH39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS07275
gene id: 526225:GOBS_RS07275
uniprot id: D2SC38
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

526225:GOBS RS04230
gene id: 526225:GOBS_RS04230
uniprot id: D2S8X5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS12020
gene id: 526225:GOBS_RS12020
uniprot id: D2S4D8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10575
gene id: 526225:GOBS_RS10575
uniprot id: D2SFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

526225:GOBS RS00530
gene id: 526225:GOBS_RS00530
uniprot id: D2SGN2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

526225:GOBS RS23985
gene id: 526225:GOBS_RS23985
uniprot id: D2S6T3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

526225:GOBS RS01880
gene id: 526225:GOBS_RS01880
uniprot id: D2S558
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526225:GOBS RS02420
gene id: 526225:GOBS_RS02420
uniprot id: D2S647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS02960
gene id: 526225:GOBS_RS02960
uniprot id: D2S773
names: Similarity
messages: Belongs to the GSP E family.

526225:GOBS RS06990
gene id: 526225:GOBS_RS06990
uniprot id: D2SBY3
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

526225:GOBS RS00760
gene id: 526225:GOBS_RS00760
uniprot id: D2S3T3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS12730
gene id: 526225:GOBS_RS12730
uniprot id: D2S5H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS18755
gene id: 526225:GOBS_RS18755
uniprot id: D2SD74
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS13205
gene id: 526225:GOBS_RS13205
uniprot id: D2S6G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526225:GOBS RS06900
gene id: 526225:GOBS_RS06900
uniprot id: D2SBW5
names: Similarity
messages: Belongs to the AHA1 family.

526225:GOBS RS01505
gene id: 526225:GOBS_RS01505
uniprot id: D2S4Z4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

526225:GOBS RS21940
gene id: 526225:GOBS_RS21940
uniprot id: D2SH79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

526225:GOBS RS18855
gene id: 526225:GOBS_RS18855
uniprot id: D2SD94
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

526225:GOBS RS22675
gene id: 526225:GOBS_RS22675
uniprot id: D2S4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

526225:GOBS RS21645
gene id: 526225:GOBS_RS21645
uniprot id: D2SGB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

526225:GOBS RS12090
gene id: 526225:GOBS_RS12090
uniprot id: D2S4F2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

526225:GOBS RS17175
gene id: 526225:GOBS_RS17175
uniprot id: D2SBJ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

526225:GOBS RS14870
gene id: 526225:GOBS_RS14870
uniprot id: D2S8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

526225:GOBS RS15950
gene id: 526225:GOBS_RS15950
uniprot id: D2SA45
names: Similarity
messages: Belongs to the YggT family.

526225:GOBS RS12220
gene id: 526225:GOBS_RS12220
uniprot id: D2S4H8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

526225:GOBS RS21405
gene id: 526225:GOBS_RS21405
uniprot id: D2SG62
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

526225:GOBS RS05105
gene id: 526225:GOBS_RS05105
uniprot id: D2S9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS23465
gene id: 526225:GOBS_RS23465
uniprot id: D2S5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

526225:GOBS RS04510
gene id: 526225:GOBS_RS04510
uniprot id: D2S928
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS24595
gene id: 526225:GOBS_RS24595
uniprot id: D2S7W6
names: Similarity
messages: Belongs to the asparagine synthetase family.

526225:GOBS RS22050
gene id: 526225:GOBS_RS22050
uniprot id: D2SHA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

526225:GOBS RS20035
gene id: 526225:GOBS_RS20035
uniprot id: D2SEN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

526225:GOBS RS28955
gene id: 526225:GOBS_RS28955
uniprot id: D2SCK2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526225:GOBS RS08055
gene id: 526225:GOBS_RS08055
uniprot id: D2SCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

526225:GOBS RS15265
gene id: 526225:GOBS_RS15265
uniprot id: D2S9D0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS19655
gene id: 526225:GOBS_RS19655
uniprot id: D2SE28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

526225:GOBS RS14540
gene id: 526225:GOBS_RS14540
uniprot id: D2S8L0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

526225:GOBS RS16525
gene id: 526225:GOBS_RS16525
uniprot id: D2SAU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

526225:GOBS RS22690
gene id: 526225:GOBS_RS22690
uniprot id: D2S4N1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

526225:GOBS RS15410
gene id: 526225:GOBS_RS15410
uniprot id: D2S9F9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

526225:GOBS RS24145
gene id: 526225:GOBS_RS24145
uniprot id: D2S6W5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS00545
gene id: 526225:GOBS_RS00545
uniprot id: D2SGN5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

526225:GOBS RS12940
gene id: 526225:GOBS_RS12940
uniprot id: D2S5K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS20015
gene id: 526225:GOBS_RS20015
uniprot id: D2SEM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526225:GOBS RS19580
gene id: 526225:GOBS_RS19580
uniprot id: D2SE14
names: Similarity
messages: Belongs to the P(II) protein family.

526225:GOBS RS25810
gene id: 526225:GOBS_RS25810
uniprot id: D2SHF0
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

526225:GOBS RS19410
gene id: 526225:GOBS_RS19410
uniprot id: D2SDY1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

526225:GOBS RS10080
gene id: 526225:GOBS_RS10080
uniprot id: D2SF60
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

526225:GOBS RS04795
gene id: 526225:GOBS_RS04795
uniprot id: D2S9L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

526225:GOBS RS01790
gene id: 526225:GOBS_RS01790
uniprot id: D2S542
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15690
gene id: 526225:GOBS_RS15690
uniprot id: D2S9K9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22070
gene id: 526225:GOBS_RS22070
uniprot id: D2SHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

526225:GOBS RS15105
gene id: 526225:GOBS_RS15105
uniprot id: D2S9A0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS13485
gene id: 526225:GOBS_RS13485
uniprot id: D2S6L4
names: Similarity
messages: Belongs to the hyi family.

526225:GOBS RS10960
gene id: 526225:GOBS_RS10960
uniprot id: D2SGT0
names: Similarity
messages: Belongs to the peptidase S8 family.

526225:GOBS RS19825
gene id: 526225:GOBS_RS19825
uniprot id: D2SEI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526225:GOBS RS15005
gene id: 526225:GOBS_RS15005
uniprot id: D2S8V0
names: Subunit
messages: Homodimer.

526225:GOBS RS22880
gene id: 526225:GOBS_RS22880
uniprot id: D2S4S0
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS01290
gene id: 526225:GOBS_RS01290
uniprot id: D2S437
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526225:GOBS RS21425
gene id: 526225:GOBS_RS21425
uniprot id: D2SG66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

526225:GOBS RS06520
gene id: 526225:GOBS_RS06520
uniprot id: D2SBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

526225:GOBS RS21050
gene id: 526225:GOBS_RS21050
uniprot id: D2SFL4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

526225:GOBS RS24570
gene id: 526225:GOBS_RS24570
uniprot id: D2S7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

526225:GOBS RS05135
gene id: 526225:GOBS_RS05135
uniprot id: D2S9T1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

526225:GOBS RS06375
gene id: 526225:GOBS_RS06375
uniprot id: D2SB86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS03900
gene id: 526225:GOBS_RS03900
uniprot id: D2S8C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS20220
gene id: 526225:GOBS_RS20220
uniprot id: D2SER6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

526225:GOBS RS10200
gene id: 526225:GOBS_RS10200
uniprot id: D2SFL8
names: Similarity
messages: Belongs to the peptidase C40 family.

526225:GOBS RS02720
gene id: 526225:GOBS_RS02720
uniprot id: D2S6A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

526225:GOBS RS02415
gene id: 526225:GOBS_RS02415
uniprot id: D2S646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS14070
gene id: 526225:GOBS_RS14070
uniprot id: D2S7P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

526225:GOBS RS19910
gene id: 526225:GOBS_RS19910
uniprot id: D2SEK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS08480
gene id: 526225:GOBS_RS08480
uniprot id: D2SDI1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS18420
gene id: 526225:GOBS_RS18420
uniprot id: D2SD07
names: Similarity
messages: Belongs to the DapA family.

526225:GOBS RS10905
gene id: 526225:GOBS_RS10905
uniprot id: D2SGR9
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS15425
gene id: 526225:GOBS_RS15425
uniprot id: D2S9G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

526225:GOBS RS16625
gene id: 526225:GOBS_RS16625
uniprot id: D2SAV9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS20285
gene id: 526225:GOBS_RS20285
uniprot id: D2SES9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

526225:GOBS RS11380
gene id: 526225:GOBS_RS11380
uniprot id: D2SH12
names: Similarity
messages: Belongs to the asparaginase 1 family.

526225:GOBS RS15385
gene id: 526225:GOBS_RS15385
uniprot id: D2S9F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

526225:GOBS RS22945
gene id: 526225:GOBS_RS22945
uniprot id: D2S4T3
names: Similarity
messages: Belongs to the asp23 family.

526225:GOBS RS19635
gene id: 526225:GOBS_RS19635
uniprot id: D2SE24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

526225:GOBS RS07495
gene id: 526225:GOBS_RS07495
uniprot id: D2SC80
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

526225:GOBS RS04800
gene id: 526225:GOBS_RS04800
uniprot id: D2S9L5
names: Similarity
messages: Belongs to the MotB family.

526225:GOBS RS06880
gene id: 526225:GOBS_RS06880
uniprot id: D2SBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

526225:GOBS RS20490
gene id: 526225:GOBS_RS20490
uniprot id: D2SFA0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

526225:GOBS RS09010
gene id: 526225:GOBS_RS09010
uniprot id: D2SE66
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS08155
gene id: 526225:GOBS_RS08155
uniprot id: D2SCY4
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS07975
gene id: 526225:GOBS_RS07975
uniprot id: D2SCU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

526225:GOBS RS21215
gene id: 526225:GOBS_RS21215
uniprot id: D2SG31
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

526225:GOBS RS05430
gene id: 526225:GOBS_RS05430
uniprot id: D2S9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

526225:GOBS RS16510
gene id: 526225:GOBS_RS16510
uniprot id: D2SAT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

526225:GOBS RS07695
gene id: 526225:GOBS_RS07695
uniprot id: D2SCQ0
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

526225:GOBS RS02740
gene id: 526225:GOBS_RS02740
uniprot id: D2S6B0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

526225:GOBS RS24395
gene id: 526225:GOBS_RS24395
uniprot id: D2S715
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS15275
gene id: 526225:GOBS_RS15275
uniprot id: D2S9D2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS15545
gene id: 526225:GOBS_RS15545
uniprot id: D2S9I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

526225:GOBS RS14045
gene id: 526225:GOBS_RS14045
uniprot id: D2S7P0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

526225:GOBS RS22830
gene id: 526225:GOBS_RS22830
uniprot id: D2S4Q9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

526225:GOBS RS04995
gene id: 526225:GOBS_RS04995
uniprot id: D2S9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

526225:GOBS RS15540
gene id: 526225:GOBS_RS15540
uniprot id: D2S9I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

526225:GOBS RS16620
gene id: 526225:GOBS_RS16620
uniprot id: D2SAV8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

526225:GOBS RS21980
gene id: 526225:GOBS_RS21980
uniprot id: D2SH87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

526225:GOBS RS24710
gene id: 526225:GOBS_RS24710
uniprot id: D2S7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

526225:GOBS RS18655
gene id: 526225:GOBS_RS18655
uniprot id: D2SD54
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS03895
gene id: 526225:GOBS_RS03895
uniprot id: D2S8C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

526225:GOBS RS04675
gene id: 526225:GOBS_RS04675
uniprot id: D2S959
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

526225:GOBS RS05195
gene id: 526225:GOBS_RS05195
uniprot id: D2S9U2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS02795
gene id: 526225:GOBS_RS02795
uniprot id: D2S739
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

526225:GOBS RS05360
gene id: 526225:GOBS_RS05360
uniprot id: D2S9X4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

526225:GOBS RS16355
gene id: 526225:GOBS_RS16355
uniprot id: D2SAC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS25495
gene id: 526225:GOBS_RS25495
uniprot id: D2S7N0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

526225:GOBS RS04860
gene id: 526225:GOBS_RS04860
uniprot id: D2S9M7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

526225:GOBS RS13380
gene id: 526225:GOBS_RS13380
uniprot id: D2S6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

526225:GOBS RS10005
gene id: 526225:GOBS_RS10005
uniprot id: D2SF43
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

526225:GOBS RS05035
gene id: 526225:GOBS_RS05035
uniprot id: D2S9R2
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS22430
gene id: 526225:GOBS_RS22430
uniprot id: D2SHH5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

526225:GOBS RS04805
gene id: 526225:GOBS_RS04805
uniprot id: D2S9L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

526225:GOBS RS22130
gene id: 526225:GOBS_RS22130
uniprot id: D2SHB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

526225:GOBS RS21935
gene id: 526225:GOBS_RS21935
uniprot id: D2SH78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

526225:GOBS RS14255
gene id: 526225:GOBS_RS14255
uniprot id: D2S7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

526225:GOBS RS21800
gene id: 526225:GOBS_RS21800
uniprot id: D2SH51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

526225:GOBS RS18560
gene id: 526225:GOBS_RS18560
uniprot id: D2SD35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS16270
gene id: 526225:GOBS_RS16270
uniprot id: D2SAB0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

526225:GOBS RS08435
gene id: 526225:GOBS_RS08435
uniprot id: D2SDH1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

526225:GOBS RS06710
gene id: 526225:GOBS_RS06710
uniprot id: D2SBF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

526225:GOBS RS01515
gene id: 526225:GOBS_RS01515
uniprot id: D2S4Z6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526225:GOBS RS23900
gene id: 526225:GOBS_RS23900
uniprot id: D2S6R7
names: Similarity
messages: Belongs to the AHA1 family.

526225:GOBS RS15530
gene id: 526225:GOBS_RS15530
uniprot id: D2S9I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

526225:GOBS RS08085
gene id: 526225:GOBS_RS08085
uniprot id: D2SCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

526225:GOBS RS11685
gene id: 526225:GOBS_RS11685
uniprot id: D2S471
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS13795
gene id: 526225:GOBS_RS13795
uniprot id: D2S7J1
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

526225:GOBS RS08380
gene id: 526225:GOBS_RS08380
uniprot id: D2SDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS10525
gene id: 526225:GOBS_RS10525
uniprot id: D2SFT0
names: Similarity
messages: Belongs to the glutamate synthase family.

526225:GOBS RS22565
gene id: 526225:GOBS_RS22565
uniprot id: D2S4K5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11710
gene id: 526225:GOBS_RS11710
uniprot id: D2S476
names: Similarity
messages: Belongs to the DapA family.

526225:GOBS RS05505
gene id: 526225:GOBS_RS05505
uniprot id: D2SAD8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

526225:GOBS RS22135
gene id: 526225:GOBS_RS22135
uniprot id: D2SHC0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

526225:GOBS RS14760
gene id: 526225:GOBS_RS14760
uniprot id: D2S8Q0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

526225:GOBS RS11000
gene id: 526225:GOBS_RS11000
uniprot id: D2SGT7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS04920
gene id: 526225:GOBS_RS04920
uniprot id: D2S9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

526225:GOBS RS13830
gene id: 526225:GOBS_RS13830
uniprot id: D2S7J8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22885
gene id: 526225:GOBS_RS22885
uniprot id: D2S4S1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS12130
gene id: 526225:GOBS_RS12130
uniprot id: D2S4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS17440
gene id: 526225:GOBS_RS17440
uniprot id: D2SBP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS11915
gene id: 526225:GOBS_RS11915
uniprot id: D2S4B6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

526225:GOBS RS19400
gene id: 526225:GOBS_RS19400
uniprot id: D2SDX9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526225:GOBS RS21135
gene id: 526225:GOBS_RS21135
uniprot id: D2SG16
names: Similarity
messages: Belongs to the ABC transporter superfamily.

526225:GOBS RS05485
gene id: 526225:GOBS_RS05485
uniprot id: D2SAD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

526225:GOBS RS17620
gene id: 526225:GOBS_RS17620
uniprot id: D2SBT7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

526225:GOBS RS12205
gene id: 526225:GOBS_RS12205
uniprot id: D2S4H5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22420
gene id: 526225:GOBS_RS22420
uniprot id: D2SHH3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

526225:GOBS RS22310
gene id: 526225:GOBS_RS22310
uniprot id: D2SHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS10000
gene id: 526225:GOBS_RS10000
uniprot id: D2SF42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

526225:GOBS RS18490
gene id: 526225:GOBS_RS18490
uniprot id: D2SD22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS24635
gene id: 526225:GOBS_RS24635
uniprot id: D2S7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526225:GOBS RS23520
gene id: 526225:GOBS_RS23520
uniprot id: D2S5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

526225:GOBS RS04525
gene id: 526225:GOBS_RS04525
uniprot id: D2S930
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

526225:GOBS RS09280
gene id: 526225:GOBS_RS09280
uniprot id: D2SEC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS17170
gene id: 526225:GOBS_RS17170
uniprot id: D2SBJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

526225:GOBS RS10110
gene id: 526225:GOBS_RS10110
uniprot id: D2SF66
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

526225:GOBS RS08200
gene id: 526225:GOBS_RS08200
uniprot id: D2SDC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526225:GOBS RS19555
gene id: 526225:GOBS_RS19555
uniprot id: D2SE09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS23385
gene id: 526225:GOBS_RS23385
uniprot id: D2S5Q7
names: Similarity
messages: Belongs to the GARS family.

526225:GOBS RS15765
gene id: 526225:GOBS_RS15765
uniprot id: D2SA08
names: Similarity
messages: Belongs to the TrpC family.

526225:GOBS RS10655
gene id: 526225:GOBS_RS10655
uniprot id: D2SFV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS03165
gene id: 526225:GOBS_RS03165
uniprot id: D2S7B0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

526225:GOBS RS08605
gene id: 526225:GOBS_RS08605
uniprot id: D2SDK6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS17800
gene id: 526225:GOBS_RS17800
uniprot id: D2SCA1
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

526225:GOBS RS01325
gene id: 526225:GOBS_RS01325
uniprot id: D2S444
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10290
gene id: 526225:GOBS_RS10290
uniprot id: D2SFN5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

526225:GOBS RS10050
gene id: 526225:GOBS_RS10050
uniprot id: D2SF53
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS14470
gene id: 526225:GOBS_RS14470
uniprot id: D2S8J8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

526225:GOBS RS19960
gene id: 526225:GOBS_RS19960
uniprot id: D2SEL5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

526225:GOBS RS15500
gene id: 526225:GOBS_RS15500
uniprot id: D2S9H7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

526225:GOBS RS14310
gene id: 526225:GOBS_RS14310
uniprot id: D2S7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS00460
gene id: 526225:GOBS_RS00460
uniprot id: D2SGL8
names: Function
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

526225:GOBS RS22065
gene id: 526225:GOBS_RS22065
uniprot id: D2SHA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

526225:GOBS RS08130
gene id: 526225:GOBS_RS08130
uniprot id: D2SCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS08900
gene id: 526225:GOBS_RS08900
uniprot id: D2SE46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS15250
gene id: 526225:GOBS_RS15250
uniprot id: D2S9C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

526225:GOBS RS13735
gene id: 526225:GOBS_RS13735
uniprot id: D2S7H9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526225:GOBS RS04125
gene id: 526225:GOBS_RS04125
uniprot id: D2S8H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS24830
gene id: 526225:GOBS_RS24830
uniprot id: D2S813
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

526225:GOBS RS23535
gene id: 526225:GOBS_RS23535
uniprot id: D2S5T6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

526225:GOBS RS24575
gene id: 526225:GOBS_RS24575
uniprot id: D2S7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

526225:GOBS RS19535
gene id: 526225:GOBS_RS19535
uniprot id: D2SE05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

526225:GOBS RS14050
gene id: 526225:GOBS_RS14050
uniprot id: D2S7P1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

526225:GOBS RS23630
gene id: 526225:GOBS_RS23630
uniprot id: D2S5V1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

526225:GOBS RS24950
gene id: 526225:GOBS_RS24950
uniprot id: D2S836
names: Similarity
messages: Belongs to the ParB family.

526225:GOBS RS10510
gene id: 526225:GOBS_RS10510
uniprot id: D2SFS7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS17695
gene id: 526225:GOBS_RS17695
uniprot id: D2SC81
names: Subcellular Location Annotation
messages: Cytoplasm

526225:GOBS RS03985
gene id: 526225:GOBS_RS03985
uniprot id: D2S8E5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

526225:GOBS RS16385
gene id: 526225:GOBS_RS16385
uniprot id: D2SAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

526225:GOBS RS05275
gene id: 526225:GOBS_RS05275
uniprot id: D2S9V7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23130
gene id: 526225:GOBS_RS23130
uniprot id: D2S5L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS05375
gene id: 526225:GOBS_RS05375
uniprot id: D2S9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS09925
gene id: 526225:GOBS_RS09925
uniprot id: D2SF27
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS17635
gene id: 526225:GOBS_RS17635
uniprot id: D2SBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

526225:GOBS RS15830
gene id: 526225:GOBS_RS15830
uniprot id: D2SA20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

526225:GOBS RS07790
gene id: 526225:GOBS_RS07790
uniprot id: D2SCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

526225:GOBS RS22005
gene id: 526225:GOBS_RS22005
uniprot id: D2SH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

526225:GOBS RS19770
gene id: 526225:GOBS_RS19770
uniprot id: D2SEI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526225:GOBS RS19010
gene id: 526225:GOBS_RS19010
uniprot id: D2SDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

526225:GOBS RS15535
gene id: 526225:GOBS_RS15535
uniprot id: D2S9I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

526225:GOBS RS15750
gene id: 526225:GOBS_RS15750
uniprot id: D2SA05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

526225:GOBS RS06770
gene id: 526225:GOBS_RS06770
uniprot id: D2SBG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS16025
gene id: 526225:GOBS_RS16025
uniprot id: D2SA60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

526225:GOBS RS08370
gene id: 526225:GOBS_RS08370
uniprot id: D2SDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

526225:GOBS RS08965
gene id: 526225:GOBS_RS08965
uniprot id: D2SE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

526225:GOBS RS20275
gene id: 526225:GOBS_RS20275
uniprot id: D2SES7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS06610
gene id: 526225:GOBS_RS06610
uniprot id: D2SBD2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22010
gene id: 526225:GOBS_RS22010
uniprot id: D2SH93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

526225:GOBS RS23365
gene id: 526225:GOBS_RS23365
uniprot id: D2S5Q3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

526225:GOBS RS20300
gene id: 526225:GOBS_RS20300
uniprot id: D2SET2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS08425
gene id: 526225:GOBS_RS08425
uniprot id: D2SDG9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS17850
gene id: 526225:GOBS_RS17850
uniprot id: D2SCB1
names: Similarity
messages: Belongs to the YciI family.

526225:GOBS RS22270
gene id: 526225:GOBS_RS22270
uniprot id: D2SHE3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

526225:GOBS RS20225
gene id: 526225:GOBS_RS20225
uniprot id: D2SER7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

526225:GOBS RS14055
gene id: 526225:GOBS_RS14055
uniprot id: D2S7P2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

526225:GOBS RS13895
gene id: 526225:GOBS_RS13895
uniprot id: D2S7L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

526225:GOBS RS01495
gene id: 526225:GOBS_RS01495
uniprot id: D2S4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

526225:GOBS RS12835
gene id: 526225:GOBS_RS12835
uniprot id: D2S5I6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS13330
gene id: 526225:GOBS_RS13330
uniprot id: D2S6I7
names: Similarity
messages: Belongs to the UPF0749 family.

526225:GOBS RS08635
gene id: 526225:GOBS_RS08635
uniprot id: D2SDL2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

526225:GOBS RS19055
gene id: 526225:GOBS_RS19055
uniprot id: D2SDR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS07130
gene id: 526225:GOBS_RS07130
uniprot id: D2SC11
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

526225:GOBS RS17740
gene id: 526225:GOBS_RS17740
uniprot id: D2SC89
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15200
gene id: 526225:GOBS_RS15200
uniprot id: D2S9B7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

526225:GOBS RS00695
gene id: 526225:GOBS_RS00695
uniprot id: D2S3S0
names: Similarity
messages: Belongs to the cytochrome P450 family.

526225:GOBS RS04020
gene id: 526225:GOBS_RS04020
uniprot id: D2S8F2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS09625
gene id: 526225:GOBS_RS09625
uniprot id: D2SEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

526225:GOBS RS22055
gene id: 526225:GOBS_RS22055
uniprot id: D2SHA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

526225:GOBS RS11525
gene id: 526225:GOBS_RS11525
uniprot id: D2SH38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

526225:GOBS RS14955
gene id: 526225:GOBS_RS14955
uniprot id: D2S8U0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

526225:GOBS RS15985
gene id: 526225:GOBS_RS15985
uniprot id: D2SA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

526225:GOBS RS17690
gene id: 526225:GOBS_RS17690
uniprot id: D2SBV1
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS24815
gene id: 526225:GOBS_RS24815
uniprot id: D2S810
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

526225:GOBS RS24985
gene id: 526225:GOBS_RS24985
uniprot id: D2S843
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

526225:GOBS RS21945
gene id: 526225:GOBS_RS21945
uniprot id: D2SH80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

526225:GOBS RS09450
gene id: 526225:GOBS_RS09450
uniprot id: D2SEF4
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

526225:GOBS RS04620
gene id: 526225:GOBS_RS04620
uniprot id: D2S948
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526225:GOBS RS15300
gene id: 526225:GOBS_RS15300
uniprot id: D2S9D6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

526225:GOBS RS14110
gene id: 526225:GOBS_RS14110
uniprot id: D2S7Q3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS19425
gene id: 526225:GOBS_RS19425
uniprot id: D2SDY4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

526225:GOBS RS22515
gene id: 526225:GOBS_RS22515
uniprot id: D2S4J5
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

526225:GOBS RS18390
gene id: 526225:GOBS_RS18390
uniprot id: D2SD01
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS04465
gene id: 526225:GOBS_RS04465
uniprot id: D2S919
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16340
gene id: 526225:GOBS_RS16340
uniprot id: D2SAC2
names: Similarity
messages: Belongs to the peptidase C40 family.

526225:GOBS RS21415
gene id: 526225:GOBS_RS21415
uniprot id: D2SG64
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

526225:GOBS RS23540
gene id: 526225:GOBS_RS23540
uniprot id: D2S5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

526225:GOBS RS02725
gene id: 526225:GOBS_RS02725
uniprot id: D2S6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

526225:GOBS RS00055
gene id: 526225:GOBS_RS00055
uniprot id: D2SGE1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

526225:GOBS RS11540
gene id: 526225:GOBS_RS11540
uniprot id: D2SH41
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526225:GOBS RS15945
gene id: 526225:GOBS_RS15945
uniprot id: D2SA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

526225:GOBS RS04785
gene id: 526225:GOBS_RS04785
uniprot id: D2S982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

526225:GOBS RS10700
gene id: 526225:GOBS_RS10700
uniprot id: D2SFW5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

526225:GOBS RS14690
gene id: 526225:GOBS_RS14690
uniprot id: D2S8P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS19740
gene id: 526225:GOBS_RS19740
uniprot id: D2SEH5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526225:GOBS RS21590
gene id: 526225:GOBS_RS21590
uniprot id: D2SG99
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

526225:GOBS RS25320
gene id: 526225:GOBS_RS25320
uniprot id: D2SDJ7
names: Similarity
messages: Belongs to the AHA1 family.

526225:GOBS RS04910
gene id: 526225:GOBS_RS04910
uniprot id: D2S9N7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

526225:GOBS RS20040
gene id: 526225:GOBS_RS20040
uniprot id: D2SEN1
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

526225:GOBS RS13280
gene id: 526225:GOBS_RS13280
uniprot id: D2S6H7
names: Similarity
messages: Belongs to the UPF0098 family.

526225:GOBS RS00960
gene id: 526225:GOBS_RS00960
uniprot id: D2S3X2
names: Similarity
messages: Belongs to the UreD family.

526225:GOBS RS07645
gene id: 526225:GOBS_RS07645
uniprot id: D2SCP1
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

526225:GOBS RS08265
gene id: 526225:GOBS_RS08265
uniprot id: D2SDD8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

526225:GOBS RS03750
gene id: 526225:GOBS_RS03750
uniprot id: D2S8A3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

526225:GOBS RS21340
gene id: 526225:GOBS_RS21340
uniprot id: D2SG49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

526225:GOBS RS23265
gene id: 526225:GOBS_RS23265
uniprot id: D2S5N1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

526225:GOBS RS02460
gene id: 526225:GOBS_RS02460
uniprot id: D2S655
names: Similarity
messages: Belongs to the pirin family.

526225:GOBS RS21730
gene id: 526225:GOBS_RS21730
uniprot id: D2SGC4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

526225:GOBS RS03215
gene id: 526225:GOBS_RS03215
uniprot id: D2S7C0
names: Similarity
messages: Belongs to the Nth/MutY family.

526225:GOBS RS29100
gene id: 526225:GOBS_RS29100
uniprot id: D2S7Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

526225:GOBS RS16770
gene id: 526225:GOBS_RS16770
uniprot id: D2SAY7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS17795
gene id: 526225:GOBS_RS17795
uniprot id: D2SCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

526225:GOBS RS21465
gene id: 526225:GOBS_RS21465
uniprot id: D2SG74
names: Similarity
messages: Belongs to the UPRTase family.

526225:GOBS RS15315
gene id: 526225:GOBS_RS15315
uniprot id: D2S9D9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

526225:GOBS RS16295
gene id: 526225:GOBS_RS16295
uniprot id: D2SAB5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

526225:GOBS RS18640
gene id: 526225:GOBS_RS18640
uniprot id: D2SD51
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526225:GOBS RS23350
gene id: 526225:GOBS_RS23350
uniprot id: D2S5Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526225:GOBS RS14015
gene id: 526225:GOBS_RS14015
uniprot id: D2S7N5
names: Similarity
messages: Belongs to the CdaR family.

526225:GOBS RS19870
gene id: 526225:GOBS_RS19870
uniprot id: D2SEJ7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

526225:GOBS RS11965
gene id: 526225:GOBS_RS11965
uniprot id: D2S4C6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS16705
gene id: 526225:GOBS_RS16705
uniprot id: D2SAX5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS24550
gene id: 526225:GOBS_RS24550
uniprot id: D2S7V7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

526225:GOBS RS00050
gene id: 526225:GOBS_RS00050
uniprot id: D2SGE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

526225:GOBS RS16260
gene id: 526225:GOBS_RS16260
uniprot id: D2SAA8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

526225:GOBS RS21785
gene id: 526225:GOBS_RS21785
uniprot id: D2SH48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

526225:GOBS RS17730
gene id: 526225:GOBS_RS17730
uniprot id: D2SC87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

526225:GOBS RS12340
gene id: 526225:GOBS_RS12340
uniprot id: D2S5B2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS16820
gene id: 526225:GOBS_RS16820
uniprot id: D2SAZ7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19865
gene id: 526225:GOBS_RS19865
uniprot id: D2SEJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS19445
gene id: 526225:GOBS_RS19445
uniprot id: D2SDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

526225:GOBS RS24555
gene id: 526225:GOBS_RS24555
uniprot id: D2S7V8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

526225:GOBS RS24695
gene id: 526225:GOBS_RS24695
uniprot id: D2S7Y6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

526225:GOBS RS03955
gene id: 526225:GOBS_RS03955
uniprot id: D2S8D9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526225:GOBS RS14140
gene id: 526225:GOBS_RS14140
uniprot id: D2S7Q9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

526225:GOBS RS15320
gene id: 526225:GOBS_RS15320
uniprot id: D2S9E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

526225:GOBS RS23945
gene id: 526225:GOBS_RS23945
uniprot id: D2S6S6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526225:GOBS RS24770
gene id: 526225:GOBS_RS24770
uniprot id: D2S800
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11715
gene id: 526225:GOBS_RS11715
uniprot id: D2S477
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

526225:GOBS RS13580
gene id: 526225:GOBS_RS13580
uniprot id: D2S6N3
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

526225:GOBS RS06240
gene id: 526225:GOBS_RS06240
uniprot id: D2SB62
names: Similarity
messages: Belongs to the aldose epimerase family.

526225:GOBS RS04950
gene id: 526225:GOBS_RS04950
uniprot id: D2S9P5
names: Similarity
messages: Belongs to the peptidase C40 family.

526225:GOBS RS13325
gene id: 526225:GOBS_RS13325
uniprot id: D2S6I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

526225:GOBS RS19310
gene id: 526225:GOBS_RS19310
uniprot id: D2SDW1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

526225:GOBS RS20165
gene id: 526225:GOBS_RS20165
uniprot id: D2SEQ5
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

526225:GOBS RS15110
gene id: 526225:GOBS_RS15110
uniprot id: D2S9A1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526225:GOBS RS04490
gene id: 526225:GOBS_RS04490
uniprot id: D2S924
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

526225:GOBS RS13665
gene id: 526225:GOBS_RS13665
uniprot id: D2S6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS20870
gene id: 526225:GOBS_RS20870
uniprot id: D2SFH8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

526225:GOBS RS20795
gene id: 526225:GOBS_RS20795
uniprot id: D2SFG2
names: Similarity
messages: Belongs to the DEAD box helicase family.

526225:GOBS RS14025
gene id: 526225:GOBS_RS14025
uniprot id: D2S7N7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

526225:GOBS RS24730
gene id: 526225:GOBS_RS24730
uniprot id: D2S7Z3
names: Similarity
messages: Belongs to the CobT family.

526225:GOBS RS07310
gene id: 526225:GOBS_RS07310
uniprot id: D2SC44
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

526225:GOBS RS13805
gene id: 526225:GOBS_RS13805
uniprot id: D2S7J3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS13670
gene id: 526225:GOBS_RS13670
uniprot id: D2S7G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS23650
gene id: 526225:GOBS_RS23650
uniprot id: D2S5V5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

526225:GOBS RS21520
gene id: 526225:GOBS_RS21520
uniprot id: D2SG85
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

526225:GOBS RS04855
gene id: 526225:GOBS_RS04855
uniprot id: D2S9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

526225:GOBS RS12005
gene id: 526225:GOBS_RS12005
uniprot id: D2S4D5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

526225:GOBS RS12990
gene id: 526225:GOBS_RS12990
uniprot id: D2S6C1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

526225:GOBS RS07530
gene id: 526225:GOBS_RS07530
uniprot id: D2SCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

526225:GOBS RS20290
gene id: 526225:GOBS_RS20290
uniprot id: D2SET0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

526225:GOBS RS20500
gene id: 526225:GOBS_RS20500
uniprot id: D2SFA2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

526225:GOBS RS18505
gene id: 526225:GOBS_RS18505
uniprot id: D2SD25
names: Function
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

526225:GOBS RS25130
gene id: 526225:GOBS_RS25130
uniprot id: D2S7D8
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS24525
gene id: 526225:GOBS_RS24525
uniprot id: D2S7V2
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

526225:GOBS RS13690
gene id: 526225:GOBS_RS13690
uniprot id: D2S7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS11205
gene id: 526225:GOBS_RS11205
uniprot id: D2SGX7
names: Similarity
messages: Belongs to the UPF0303 family.

526225:GOBS RS24945
gene id: 526225:GOBS_RS24945
uniprot id: D2S835
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

526225:GOBS RS19995
gene id: 526225:GOBS_RS19995
uniprot id: D2SEM2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS14815
gene id: 526225:GOBS_RS14815
uniprot id: D2S8R1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

526225:GOBS RS04115
gene id: 526225:GOBS_RS04115
uniprot id: D2S8H1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS10395
gene id: 526225:GOBS_RS10395
uniprot id: D2SFQ6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14940
gene id: 526225:GOBS_RS14940
uniprot id: D2S8T7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS14835
gene id: 526225:GOBS_RS14835
uniprot id: D2S8R6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

526225:GOBS RS12870
gene id: 526225:GOBS_RS12870
uniprot id: D2S558
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526225:GOBS RS05960
gene id: 526225:GOBS_RS05960
uniprot id: D2SAM8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19460
gene id: 526225:GOBS_RS19460
uniprot id: D2SDZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

526225:GOBS RS01830
gene id: 526225:GOBS_RS01830
uniprot id: D2S549
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

526225:GOBS RS02175
gene id: 526225:GOBS_RS02175
uniprot id: D2S602
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS12025
gene id: 526225:GOBS_RS12025
uniprot id: D2S4D9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19465
gene id: 526225:GOBS_RS19465
uniprot id: D2SDZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

526225:GOBS RS13800
gene id: 526225:GOBS_RS13800
uniprot id: D2S7J2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS10030
gene id: 526225:GOBS_RS10030
uniprot id: D2SF48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526225:GOBS RS01725
gene id: 526225:GOBS_RS01725
uniprot id: D2S530
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

526225:GOBS RS23770
gene id: 526225:GOBS_RS23770
uniprot id: D2S5X9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

526225:GOBS RS09190
gene id: 526225:GOBS_RS09190
uniprot id: D2SEA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

526225:GOBS RS20455
gene id: 526225:GOBS_RS20455
uniprot id: D2SF93
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

526225:GOBS RS10860
gene id: 526225:GOBS_RS10860
uniprot id: D2SFZ7
names: Subunit
messages: Monomer.

526225:GOBS RS24175
gene id: 526225:GOBS_RS24175
uniprot id: D2S6X1
names: Similarity
messages: Belongs to the UPF0225 family.

526225:GOBS RS00425
gene id: 526225:GOBS_RS00425
uniprot id: D2SGL2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14455
gene id: 526225:GOBS_RS14455
uniprot id: D2S8J5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

526225:GOBS RS22390
gene id: 526225:GOBS_RS22390
uniprot id: D2SHG7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS02480
gene id: 526225:GOBS_RS02480
uniprot id: D2S659
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526225:GOBS RS16775
gene id: 526225:GOBS_RS16775
uniprot id: D2SAY8
names: Similarity
messages: Belongs to the GSP E family.

526225:GOBS RS12520
gene id: 526225:GOBS_RS12520
uniprot id: D2S5E1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

526225:GOBS RS00310
gene id: 526225:GOBS_RS00310
uniprot id: D2SGI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS20230
gene id: 526225:GOBS_RS20230
uniprot id: D2SER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

526225:GOBS RS09560
gene id: 526225:GOBS_RS09560
uniprot id: D2SEV4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526225:GOBS RS02490
gene id: 526225:GOBS_RS02490
uniprot id: D2S661
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11560
gene id: 526225:GOBS_RS11560
uniprot id: D2SH45
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15745
gene id: 526225:GOBS_RS15745
uniprot id: D2SA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

526225:GOBS RS04815
gene id: 526225:GOBS_RS04815
uniprot id: D2S9L8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

526225:GOBS RS13220
gene id: 526225:GOBS_RS13220
uniprot id: D2S6G5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS01140
gene id: 526225:GOBS_RS01140
uniprot id: D2S408
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

526225:GOBS RS16390
gene id: 526225:GOBS_RS16390
uniprot id: D2SAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

526225:GOBS RS22490
gene id: 526225:GOBS_RS22490
uniprot id: D2S4J1
names: Similarity
messages: Belongs to the peptidase C56 family.

526225:GOBS RS21790
gene id: 526225:GOBS_RS21790
uniprot id: D2SH49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

526225:GOBS RS00710
gene id: 526225:GOBS_RS00710
uniprot id: D2S3S3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

526225:GOBS RS22040
gene id: 526225:GOBS_RS22040
uniprot id: D2SH99
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

526225:GOBS RS24960
gene id: 526225:GOBS_RS24960
uniprot id: D2S838
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

526225:GOBS RS00095
gene id: 526225:GOBS_RS00095
uniprot id: D2SGE7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

526225:GOBS RS04135
gene id: 526225:GOBS_RS04135
uniprot id: D2S8V4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

526225:GOBS RS17700
gene id: 526225:GOBS_RS17700
uniprot id: D2SC82
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16245
gene id: 526225:GOBS_RS16245
uniprot id: D2SAA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

526225:GOBS RS21565
gene id: 526225:GOBS_RS21565
uniprot id: D2SG95
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

526225:GOBS RS21850
gene id: 526225:GOBS_RS21850
uniprot id: D2SH61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS15415
gene id: 526225:GOBS_RS15415
uniprot id: D2S9G0
names: Similarity
messages: Belongs to the peptidase A24 family.

526225:GOBS RS03870
gene id: 526225:GOBS_RS03870
uniprot id: D2S8C1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS07520
gene id: 526225:GOBS_RS07520
uniprot id: D2SCL8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14570
gene id: 526225:GOBS_RS14570
uniprot id: D2S8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS10015
gene id: 526225:GOBS_RS10015
uniprot id: D2SF45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS19215
gene id: 526225:GOBS_RS19215
uniprot id: D2SDU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

526225:GOBS RS03295
gene id: 526225:GOBS_RS03295
uniprot id: D2S7D6
names: Similarity
messages: Belongs to the peptidase S1C family.

526225:GOBS RS24835
gene id: 526225:GOBS_RS24835
uniprot id: D2S814
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS03375
gene id: 526225:GOBS_RS03375
uniprot id: D2S7F0
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS20180
gene id: 526225:GOBS_RS20180
uniprot id: D2SEQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS17605
gene id: 526225:GOBS_RS17605
uniprot id: D2SBT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526225:GOBS RS05680
gene id: 526225:GOBS_RS05680
uniprot id: D2SAH3
names: Similarity
messages: Belongs to the TPP enzyme family.

526225:GOBS RS00495
gene id: 526225:GOBS_RS00495
uniprot id: D2SGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

526225:GOBS RS19220
gene id: 526225:GOBS_RS19220
uniprot id: D2SDU7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

526225:GOBS RS07900
gene id: 526225:GOBS_RS07900
uniprot id: D2SCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS14345
gene id: 526225:GOBS_RS14345
uniprot id: D2S8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

526225:GOBS RS21865
gene id: 526225:GOBS_RS21865
uniprot id: D2SH64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

526225:GOBS RS12935
gene id: 526225:GOBS_RS12935
uniprot id: D2S5K4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

526225:GOBS RS00840
gene id: 526225:GOBS_RS00840
uniprot id: D2S3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

526225:GOBS RS09165
gene id: 526225:GOBS_RS09165
uniprot id: D2SE97
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

526225:GOBS RS14315
gene id: 526225:GOBS_RS14315
uniprot id: D2S7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS17825
gene id: 526225:GOBS_RS17825
uniprot id: D2SCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS09630
gene id: 526225:GOBS_RS09630
uniprot id: D2SEW9
names: Similarity
messages: Belongs to the peptidase S9C family.

526225:GOBS RS03075
gene id: 526225:GOBS_RS03075
uniprot id: D2S794
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

526225:GOBS RS02535
gene id: 526225:GOBS_RS02535
uniprot id: D2S670
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS18380
gene id: 526225:GOBS_RS18380
uniprot id: D2SCZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS21845
gene id: 526225:GOBS_RS21845
uniprot id: D2SH60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

526225:GOBS RS19130
gene id: 526225:GOBS_RS19130
uniprot id: D2SDT0
names: Similarity
messages: Belongs to the PspA/IM30 family.

526225:GOBS RS15885
gene id: 526225:GOBS_RS15885
uniprot id: D2SA32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

526225:GOBS RS20295
gene id: 526225:GOBS_RS20295
uniprot id: D2SET1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

526225:GOBS RS01150
gene id: 526225:GOBS_RS01150
uniprot id: D2S410
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11820
gene id: 526225:GOBS_RS11820
uniprot id: D2S497
names: Subcellular Location Annotation
messages: Cytoplasm

526225:GOBS RS21535
gene id: 526225:GOBS_RS21535
uniprot id: D2SG88
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS18940
gene id: 526225:GOBS_RS18940
uniprot id: D2SDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526225:GOBS RS19085
gene id: 526225:GOBS_RS19085
uniprot id: D2SDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

526225:GOBS RS23310
gene id: 526225:GOBS_RS23310
uniprot id: D2S5P1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

526225:GOBS RS02660
gene id: 526225:GOBS_RS02660
uniprot id: D2S695
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS11235
gene id: 526225:GOBS_RS11235
uniprot id: D2SGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

526225:GOBS RS11335
gene id: 526225:GOBS_RS11335
uniprot id: D2SH04
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS02080
gene id: 526225:GOBS_RS02080
uniprot id: D2S592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

526225:GOBS RS13415
gene id: 526225:GOBS_RS13415
uniprot id: D2S6K3
names: Similarity
messages: Belongs to the TPP enzyme family.

526225:GOBS RS22620
gene id: 526225:GOBS_RS22620
uniprot id: D2S4L7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15380
gene id: 526225:GOBS_RS15380
uniprot id: D2S9F3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

526225:GOBS RS13680
gene id: 526225:GOBS_RS13680
uniprot id: D2S7G8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

526225:GOBS RS02470
gene id: 526225:GOBS_RS02470
uniprot id: D2S657
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS20515
gene id: 526225:GOBS_RS20515
uniprot id: D2SFA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

526225:GOBS RS07265
gene id: 526225:GOBS_RS07265
uniprot id: D2SC36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS16225
gene id: 526225:GOBS_RS16225
uniprot id: D2SAA1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS18695
gene id: 526225:GOBS_RS18695
uniprot id: D2SD62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

526225:GOBS RS07640
gene id: 526225:GOBS_RS07640
uniprot id: D2SCP0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

526225:GOBS RS19575
gene id: 526225:GOBS_RS19575
uniprot id: D2SE13
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

526225:GOBS RS14335
gene id: 526225:GOBS_RS14335
uniprot id: D2S7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

526225:GOBS RS11085
gene id: 526225:GOBS_RS11085
uniprot id: D2SGV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS23420
gene id: 526225:GOBS_RS23420
uniprot id: D2S5R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

526225:GOBS RS21975
gene id: 526225:GOBS_RS21975
uniprot id: D2SH86
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

526225:GOBS RS08205
gene id: 526225:GOBS_RS08205
uniprot id: D2SDC6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

526225:GOBS RS07845
gene id: 526225:GOBS_RS07845
uniprot id: D2SCS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

526225:GOBS RS04840
gene id: 526225:GOBS_RS04840
uniprot id: D2S9M3
names: Subcellular Location Annotation
messages: Cytoplasm

526225:GOBS RS13375
gene id: 526225:GOBS_RS13375
uniprot id: D2S6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

526225:GOBS RS11210
gene id: 526225:GOBS_RS11210
uniprot id: D2SGX8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21435
gene id: 526225:GOBS_RS21435
uniprot id: D2SG68
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526225:GOBS RS09915
gene id: 526225:GOBS_RS09915
uniprot id: D2SC10
names: Similarity
messages: Belongs to the RuBisCO large chain family.

526225:GOBS RS03170
gene id: 526225:GOBS_RS03170
uniprot id: D2S7B1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

526225:GOBS RS23030
gene id: 526225:GOBS_RS23030
uniprot id: D2S4U8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

526225:GOBS RS09225
gene id: 526225:GOBS_RS09225
uniprot id: D2SEA9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS02280
gene id: 526225:GOBS_RS02280
uniprot id: D2S621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

526225:GOBS RS22315
gene id: 526225:GOBS_RS22315
uniprot id: D2SHF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS10765
gene id: 526225:GOBS_RS10765
uniprot id: D2SFX8
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

526225:GOBS RS16455
gene id: 526225:GOBS_RS16455
uniprot id: D2SAS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

526225:GOBS RS04475
gene id: 526225:GOBS_RS04475
uniprot id: D2S921
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

526225:GOBS RS11060
gene id: 526225:GOBS_RS11060
uniprot id: D2SGU8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

526225:GOBS RS17530
gene id: 526225:GOBS_RS17530
uniprot id: D2SBR9
names: Subunit
messages: Homodimer.

526225:GOBS RS22170
gene id: 526225:GOBS_RS22170
uniprot id: D2SHC6
names: Similarity
messages: Belongs to the UPF0336 family.

526225:GOBS RS24850
gene id: 526225:GOBS_RS24850
uniprot id: D2S817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

526225:GOBS RS04460
gene id: 526225:GOBS_RS04460
uniprot id: D2S918
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

526225:GOBS RS05160
gene id: 526225:GOBS_RS05160
uniprot id: D2S9T5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14485
gene id: 526225:GOBS_RS14485
uniprot id: D2S8K1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS06365
gene id: 526225:GOBS_RS06365
uniprot id: D2SB84
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

526225:GOBS RS13425
gene id: 526225:GOBS_RS13425
uniprot id: D2S6K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

526225:GOBS RS19525
gene id: 526225:GOBS_RS19525
uniprot id: D2SE03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

526225:GOBS RS00945
gene id: 526225:GOBS_RS00945
uniprot id: D2S3W9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

526225:GOBS RS08320
gene id: 526225:GOBS_RS08320
uniprot id: D2SDE8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

526225:GOBS RS07850
gene id: 526225:GOBS_RS07850
uniprot id: D2SCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

526225:GOBS RS19530
gene id: 526225:GOBS_RS19530
uniprot id: D2SE04
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526225:GOBS RS16375
gene id: 526225:GOBS_RS16375
uniprot id: D2SAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

526225:GOBS RS11950
gene id: 526225:GOBS_RS11950
uniprot id: D2S4C3
names: Similarity
messages: Belongs to the IlvD/Edd family.

526225:GOBS RS10770
gene id: 526225:GOBS_RS10770
uniprot id: D2SFX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

526225:GOBS RS23440
gene id: 526225:GOBS_RS23440
uniprot id: D2S5R7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS10390
gene id: 526225:GOBS_RS10390
uniprot id: D2SFQ5
names: Similarity
messages: Belongs to the catalase family.

526225:GOBS RS04885
gene id: 526225:GOBS_RS04885
uniprot id: D2S9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

526225:GOBS RS14695
gene id: 526225:GOBS_RS14695
uniprot id: D2S8P1
names: Similarity
messages: Belongs to the TlyA family.

526225:GOBS RS15080
gene id: 526225:GOBS_RS15080
uniprot id: D2S995
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

526225:GOBS RS07125
gene id: 526225:GOBS_RS07125
uniprot id: D2SC10
names: Similarity
messages: Belongs to the RuBisCO large chain family.

526225:GOBS RS10920
gene id: 526225:GOBS_RS10920
uniprot id: D2SGS2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS09595
gene id: 526225:GOBS_RS09595
uniprot id: D2SEW1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19985
gene id: 526225:GOBS_RS19985
uniprot id: D2SEM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

526225:GOBS RS08575
gene id: 526225:GOBS_RS08575
uniprot id: D2SDK0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS17625
gene id: 526225:GOBS_RS17625
uniprot id: D2SBT8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

526225:GOBS RS02235
gene id: 526225:GOBS_RS02235
uniprot id: D2S614
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10320
gene id: 526225:GOBS_RS10320
uniprot id: D2SFP1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

526225:GOBS RS04205
gene id: 526225:GOBS_RS04205
uniprot id: D2S8W9
names: Similarity
messages: Belongs to the FPG family.

526225:GOBS RS12890
gene id: 526225:GOBS_RS12890
uniprot id: D2S5J6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14105
gene id: 526225:GOBS_RS14105
uniprot id: D2S7Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS10360
gene id: 526225:GOBS_RS10360
uniprot id: D2SFP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

526225:GOBS RS15280
gene id: 526225:GOBS_RS15280
uniprot id: D2S9D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526225:GOBS RS06080
gene id: 526225:GOBS_RS06080
uniprot id: D2SAQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

526225:GOBS RS22385
gene id: 526225:GOBS_RS22385
uniprot id: D2SHG6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS20205
gene id: 526225:GOBS_RS20205
uniprot id: D2SER3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

526225:GOBS RS22425
gene id: 526225:GOBS_RS22425
uniprot id: D2SHH4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526225:GOBS RS21985
gene id: 526225:GOBS_RS21985
uniprot id: D2SH88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

526225:GOBS RS13980
gene id: 526225:GOBS_RS13980
uniprot id: D2S7M7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

526225:GOBS RS16000
gene id: 526225:GOBS_RS16000
uniprot id: D2SA55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

526225:GOBS RS10450
gene id: 526225:GOBS_RS10450
uniprot id: D2SFR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

526225:GOBS RS23325
gene id: 526225:GOBS_RS23325
uniprot id: D2S5P4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS07810
gene id: 526225:GOBS_RS07810
uniprot id: D2SCR6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

526225:GOBS RS23760
gene id: 526225:GOBS_RS23760
uniprot id: D2S5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

526225:GOBS RS19315
gene id: 526225:GOBS_RS19315
uniprot id: D2SDW2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS13640
gene id: 526225:GOBS_RS13640
uniprot id: D2S6P5
names: Subcellular Location Annotation
messages: Cell membrane

526225:GOBS RS16490
gene id: 526225:GOBS_RS16490
uniprot id: D2SAT2
names: Similarity
messages: Belongs to the peptidase S51 family.

526225:GOBS RS08800
gene id: 526225:GOBS_RS08800
uniprot id: D2SDP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

526225:GOBS RS17590
gene id: 526225:GOBS_RS17590
uniprot id: D2SBT1
names: Similarity
messages: Belongs to the CsoR family.

526225:GOBS RS02545
gene id: 526225:GOBS_RS02545
uniprot id: D2S672
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS03940
gene id: 526225:GOBS_RS03940
uniprot id: D2S8D5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14065
gene id: 526225:GOBS_RS14065
uniprot id: D2S7P4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

526225:GOBS RS24060
gene id: 526225:GOBS_RS24060
uniprot id: D2S6U8
names: Similarity
messages: Belongs to the peptidase C40 family.

526225:GOBS RS09990
gene id: 526225:GOBS_RS09990
uniprot id: D2SF40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

526225:GOBS RS00885
gene id: 526225:GOBS_RS00885
uniprot id: D2S3W0
names: Similarity
messages: Belongs to the carbamate kinase family.

526225:GOBS RS10315
gene id: 526225:GOBS_RS10315
uniprot id: D2SFP0
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23050
gene id: 526225:GOBS_RS23050
uniprot id: D2S4V2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS04445
gene id: 526225:GOBS_RS04445
uniprot id: D2S915
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

526225:GOBS RS10980
gene id: 526225:GOBS_RS10980
uniprot id: D2SGT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS18700
gene id: 526225:GOBS_RS18700
uniprot id: D2SD63
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS20685
gene id: 526225:GOBS_RS20685
uniprot id: D2SFE0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

526225:GOBS RS05215
gene id: 526225:GOBS_RS05215
uniprot id: D2S9U6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15990
gene id: 526225:GOBS_RS15990
uniprot id: D2SA53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS17135
gene id: 526225:GOBS_RS17135
uniprot id: D2SBI9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

526225:GOBS RS05700
gene id: 526225:GOBS_RS05700
uniprot id: D2SAH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS20185
gene id: 526225:GOBS_RS20185
uniprot id: D2SEQ9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

526225:GOBS RS21620
gene id: 526225:GOBS_RS21620
uniprot id: D2SGA5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

526225:GOBS RS13295
gene id: 526225:GOBS_RS13295
uniprot id: D2S6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

526225:GOBS RS22480
gene id: 526225:GOBS_RS22480
uniprot id: D2S4I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

526225:GOBS RS20580
gene id: 526225:GOBS_RS20580
uniprot id: D2SFB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

526225:GOBS RS12540
gene id: 526225:GOBS_RS12540
uniprot id: D2S5E5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

526225:GOBS RS11615
gene id: 526225:GOBS_RS11615
uniprot id: D2S458
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11780
gene id: 526225:GOBS_RS11780
uniprot id: D2S490
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

526225:GOBS RS15585
gene id: 526225:GOBS_RS15585
uniprot id: D2S9J4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS18040
gene id: 526225:GOBS_RS18040
uniprot id: D2SCF2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526225:GOBS RS00020
gene id: 526225:GOBS_RS00020
uniprot id: D2SGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

526225:GOBS RS19755
gene id: 526225:GOBS_RS19755
uniprot id: D2SEH8
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

526225:GOBS RS14195
gene id: 526225:GOBS_RS14195
uniprot id: D2S558
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526225:GOBS RS03100
gene id: 526225:GOBS_RS03100
uniprot id: D2S799
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

526225:GOBS RS14820
gene id: 526225:GOBS_RS14820
uniprot id: D2S8R2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

526225:GOBS RS22080
gene id: 526225:GOBS_RS22080
uniprot id: D2SHA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

526225:GOBS RS16175
gene id: 526225:GOBS_RS16175
uniprot id: D2SA89
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21920
gene id: 526225:GOBS_RS21920
uniprot id: D2SH75
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

526225:GOBS RS19110
gene id: 526225:GOBS_RS19110
uniprot id: D2SDS6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS04725
gene id: 526225:GOBS_RS04725
uniprot id: D2S968
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS15090
gene id: 526225:GOBS_RS15090
uniprot id: D2S997
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526225:GOBS RS11640
gene id: 526225:GOBS_RS11640
uniprot id: D2S463
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS21640
gene id: 526225:GOBS_RS21640
uniprot id: D2SGA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

526225:GOBS RS24720
gene id: 526225:GOBS_RS24720
uniprot id: D2S7Z1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526225:GOBS RS12035
gene id: 526225:GOBS_RS12035
uniprot id: D2S4E1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21760
gene id: 526225:GOBS_RS21760
uniprot id: D2SGD0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

526225:GOBS RS15840
gene id: 526225:GOBS_RS15840
uniprot id: D2SA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

526225:GOBS RS02880
gene id: 526225:GOBS_RS02880
uniprot id: D2S756
names: Similarity
messages: Belongs to the CobH/CbiC family.

526225:GOBS RS21300
gene id: 526225:GOBS_RS21300
uniprot id: D2SG41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS10020
gene id: 526225:GOBS_RS10020
uniprot id: D2SF46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

526225:GOBS RS02145
gene id: 526225:GOBS_RS02145
uniprot id: D2S5Z6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

526225:GOBS RS11645
gene id: 526225:GOBS_RS11645
uniprot id: D2S464
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

526225:GOBS RS06535
gene id: 526225:GOBS_RS06535
uniprot id: D2SBB6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526225:GOBS RS19885
gene id: 526225:GOBS_RS19885
uniprot id: D2SEK0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS00375
gene id: 526225:GOBS_RS00375
uniprot id: D2SGK2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16010
gene id: 526225:GOBS_RS16010
uniprot id: D2SA57
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS19610
gene id: 526225:GOBS_RS19610
uniprot id: D2SE19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

526225:GOBS RS24775
gene id: 526225:GOBS_RS24775
uniprot id: D2S801
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

526225:GOBS RS19645
gene id: 526225:GOBS_RS19645
uniprot id: D2SE26
names: Similarity
messages: Belongs to the acylphosphatase family.

526225:GOBS RS19650
gene id: 526225:GOBS_RS19650
uniprot id: D2SE27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

526225:GOBS RS10060
gene id: 526225:GOBS_RS10060
uniprot id: D2SF55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

526225:GOBS RS21120
gene id: 526225:GOBS_RS21120
uniprot id: D2SG13
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

526225:GOBS RS16805
gene id: 526225:GOBS_RS16805
uniprot id: D2SAZ4
names: Similarity
messages: Belongs to the peptidase A24 family.

526225:GOBS RS07895
gene id: 526225:GOBS_RS07895
uniprot id: D2SCT3
names: Similarity
messages: Belongs to the Fur family.

526225:GOBS RS13030
gene id: 526225:GOBS_RS13030
uniprot id: D2S6C9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

526225:GOBS RS17950
gene id: 526225:GOBS_RS17950
uniprot id: D2SCD3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

526225:GOBS RS15575
gene id: 526225:GOBS_RS15575
uniprot id: D2S9J2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526225:GOBS RS19195
gene id: 526225:GOBS_RS19195
uniprot id: D2SDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

526225:GOBS RS22575
gene id: 526225:GOBS_RS22575
uniprot id: D2S4K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

526225:GOBS RS24035
gene id: 526225:GOBS_RS24035
uniprot id: D2S6U3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526225:GOBS RS14985
gene id: 526225:GOBS_RS14985
uniprot id: D2S8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS22345
gene id: 526225:GOBS_RS22345
uniprot id: D2SHF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

526225:GOBS RS01530
gene id: 526225:GOBS_RS01530
uniprot id: D2S4Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

526225:GOBS RS16470
gene id: 526225:GOBS_RS16470
uniprot id: D2SAS8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

526225:GOBS RS01055
gene id: 526225:GOBS_RS01055
uniprot id: D2S3Z2
names: Similarity
messages: Belongs to the FPG family.

526225:GOBS RS24305
gene id: 526225:GOBS_RS24305
uniprot id: D2S6Z7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22590
gene id: 526225:GOBS_RS22590
uniprot id: D2S4L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

526225:GOBS RS18450
gene id: 526225:GOBS_RS18450
uniprot id: D2SD14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

526225:GOBS RS16405
gene id: 526225:GOBS_RS16405
uniprot id: D2SAR5
names: Similarity
messages: Belongs to the asparagine synthetase family.

526225:GOBS RS09580
gene id: 526225:GOBS_RS09580
uniprot id: D2SEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

526225:GOBS RS09815
gene id: 526225:GOBS_RS09815
uniprot id: D2SF07
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14180
gene id: 526225:GOBS_RS14180
uniprot id: D2S7R5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS18660
gene id: 526225:GOBS_RS18660
uniprot id: D2SD55
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS17180
gene id: 526225:GOBS_RS17180
uniprot id: D2SBJ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

526225:GOBS RS03035
gene id: 526225:GOBS_RS03035
uniprot id: D2S787
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS08385
gene id: 526225:GOBS_RS08385
uniprot id: D2SDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS19200
gene id: 526225:GOBS_RS19200
uniprot id: D2SDU3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS13850
gene id: 526225:GOBS_RS13850
uniprot id: D2S7K2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS09445
gene id: 526225:GOBS_RS09445
uniprot id: D2SEF3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15220
gene id: 526225:GOBS_RS15220
uniprot id: D2S9C1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

526225:GOBS RS13340
gene id: 526225:GOBS_RS13340
uniprot id: D2S6I9
names: Similarity
messages: Belongs to the UPF0749 family.

526225:GOBS RS01090
gene id: 526225:GOBS_RS01090
uniprot id: D2S3Z8
names: Similarity
messages: Belongs to the manganese catalase family.

526225:GOBS RS14840
gene id: 526225:GOBS_RS14840
uniprot id: D2S8R7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

526225:GOBS RS24870
gene id: 526225:GOBS_RS24870
uniprot id: D2S821
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

526225:GOBS RS11805
gene id: 526225:GOBS_RS11805
uniprot id: D2S495
names: Similarity
messages: Belongs to the cytochrome P450 family.

526225:GOBS RS22895
gene id: 526225:GOBS_RS22895
uniprot id: D2S4S3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS17930
gene id: 526225:GOBS_RS17930
uniprot id: D2SCC9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

526225:GOBS RS13135
gene id: 526225:GOBS_RS13135
uniprot id: D2S6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

526225:GOBS RS08075
gene id: 526225:GOBS_RS08075
uniprot id: D2SCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

526225:GOBS RS10040
gene id: 526225:GOBS_RS10040
uniprot id: D2SF51
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

526225:GOBS RS23305
gene id: 526225:GOBS_RS23305
uniprot id: D2S5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

526225:GOBS RS16765
gene id: 526225:GOBS_RS16765
uniprot id: D2SAY6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21530
gene id: 526225:GOBS_RS21530
uniprot id: D2SG87
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS14305
gene id: 526225:GOBS_RS14305
uniprot id: D2S7T8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS00465
gene id: 526225:GOBS_RS00465
uniprot id: D2SGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

526225:GOBS RS19450
gene id: 526225:GOBS_RS19450
uniprot id: D2SDY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

526225:GOBS RS03040
gene id: 526225:GOBS_RS03040
uniprot id: D2S788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

526225:GOBS RS21175
gene id: 526225:GOBS_RS21175
uniprot id: D2SG23
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

526225:GOBS RS05345
gene id: 526225:GOBS_RS05345
uniprot id: D2S9X1
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS20090
gene id: 526225:GOBS_RS20090
uniprot id: D2SEP1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

526225:GOBS RS15970
gene id: 526225:GOBS_RS15970
uniprot id: D2SA49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

526225:GOBS RS20425
gene id: 526225:GOBS_RS20425
uniprot id: D2SF87
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

526225:GOBS RS19090
gene id: 526225:GOBS_RS19090
uniprot id: D2SDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

526225:GOBS RS03045
gene id: 526225:GOBS_RS03045
uniprot id: D2S789
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

526225:GOBS RS10265
gene id: 526225:GOBS_RS10265
uniprot id: D2SFN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS04530
gene id: 526225:GOBS_RS04530
uniprot id: D2S931
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

526225:GOBS RS21625
gene id: 526225:GOBS_RS21625
uniprot id: D2SGA6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS08250
gene id: 526225:GOBS_RS08250
uniprot id: D2SDD5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

526225:GOBS RS04820
gene id: 526225:GOBS_RS04820
uniprot id: D2S9L9
names: Similarity
messages: Belongs to the FlgD family.

526225:GOBS RS09770
gene id: 526225:GOBS_RS09770
uniprot id: D2SEZ8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.
messages: Belongs to the adenylyl cyclase class-3 family.

526225:GOBS RS02825
gene id: 526225:GOBS_RS02825
uniprot id: D2S745
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526225:GOBS RS02870
gene id: 526225:GOBS_RS02870
uniprot id: D2S754
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

526225:GOBS RS16255
gene id: 526225:GOBS_RS16255
uniprot id: D2SAA7
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

526225:GOBS RS02690
gene id: 526225:GOBS_RS02690
uniprot id: D2S6A0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526225:GOBS RS02950
gene id: 526225:GOBS_RS02950
uniprot id: D2S771
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

526225:GOBS RS14480
gene id: 526225:GOBS_RS14480
uniprot id: D2S8J9
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS10660
gene id: 526225:GOBS_RS10660
uniprot id: D2SFV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS14610
gene id: 526225:GOBS_RS14610
uniprot id: D2S8M4
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

526225:GOBS RS00160
gene id: 526225:GOBS_RS00160
uniprot id: D2SGG0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526225:GOBS RS11925
gene id: 526225:GOBS_RS11925
uniprot id: D2S4B8
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21605
gene id: 526225:GOBS_RS21605
uniprot id: D2SGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

526225:GOBS RS14775
gene id: 526225:GOBS_RS14775
uniprot id: D2S8Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

526225:GOBS RS13090
gene id: 526225:GOBS_RS13090
uniprot id: D2S6E1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

526225:GOBS RS03060
gene id: 526225:GOBS_RS03060
uniprot id: D2S791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

526225:GOBS RS05580
gene id: 526225:GOBS_RS05580
uniprot id: D2SAF3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS14565
gene id: 526225:GOBS_RS14565
uniprot id: D2S8L5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

526225:GOBS RS16550
gene id: 526225:GOBS_RS16550
uniprot id: D2SAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

526225:GOBS RS09495
gene id: 526225:GOBS_RS09495
uniprot id: D2SEG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526225:GOBS RS17420
gene id: 526225:GOBS_RS17420
uniprot id: D2SBP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS24925
gene id: 526225:GOBS_RS24925
uniprot id: D2S832
names: Similarity
messages: Belongs to the thioredoxin family.

526225:GOBS RS12215
gene id: 526225:GOBS_RS12215
uniprot id: D2S4H7
names: Similarity
messages: Belongs to the peptidase S8 family.

526225:GOBS RS20265
gene id: 526225:GOBS_RS20265
uniprot id: D2SES5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

526225:GOBS RS19495
gene id: 526225:GOBS_RS19495
uniprot id: D2SDZ7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

526225:GOBS RS22120
gene id: 526225:GOBS_RS22120
uniprot id: D2SHB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

526225:GOBS RS02640
gene id: 526225:GOBS_RS02640
uniprot id: D2S691
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS19330
gene id: 526225:GOBS_RS19330
uniprot id: D2SDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

526225:GOBS RS12125
gene id: 526225:GOBS_RS12125
uniprot id: D2S4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS11700
gene id: 526225:GOBS_RS11700
uniprot id: D2S474
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526225:GOBS RS21185
gene id: 526225:GOBS_RS21185
uniprot id: D2SG25
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

526225:GOBS RS01080
gene id: 526225:GOBS_RS01080
uniprot id: D2S3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

526225:GOBS RS19520
gene id: 526225:GOBS_RS19520
uniprot id: D2SE02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526225:GOBS RS23845
gene id: 526225:GOBS_RS23845
uniprot id: D2S6Q7
names: Similarity
messages: Belongs to the peptidase C40 family.

526225:GOBS RS19595
gene id: 526225:GOBS_RS19595
uniprot id: D2SE16
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS09520
gene id: 526225:GOBS_RS09520
uniprot id: D2SEG6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

526225:GOBS RS22025
gene id: 526225:GOBS_RS22025
uniprot id: D2SH96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

526225:GOBS RS16305
gene id: 526225:GOBS_RS16305
uniprot id: D2SAB7
names: Similarity
messages: Belongs to the arsA ATPase family.

526225:GOBS RS17865
gene id: 526225:GOBS_RS17865
uniprot id: D2SCB4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

526225:GOBS RS08925
gene id: 526225:GOBS_RS08925
uniprot id: D2SE51
names: Similarity
messages: Belongs to the universal stress protein A family.

526225:GOBS RS08145
gene id: 526225:GOBS_RS08145
uniprot id: D2SCY2
names: Similarity
messages: Belongs to the leucine-binding protein family.

526225:GOBS RS01190
gene id: 526225:GOBS_RS01190
uniprot id: D2S417
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19105
gene id: 526225:GOBS_RS19105
uniprot id: D2SDS5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19350
gene id: 526225:GOBS_RS19350
uniprot id: D2SDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

526225:GOBS RS25660
gene id: 526225:GOBS_RS25660
uniprot id: D2SCF8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526225:GOBS RS09920
gene id: 526225:GOBS_RS09920
uniprot id: D2SF26
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

526225:GOBS RS03010
gene id: 526225:GOBS_RS03010
uniprot id: D2S782
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

526225:GOBS RS20150
gene id: 526225:GOBS_RS20150
uniprot id: D2SEQ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS18930
gene id: 526225:GOBS_RS18930
uniprot id: D2SDA6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS09265
gene id: 526225:GOBS_RS09265
uniprot id: D2SEB7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526225:GOBS RS14655
gene id: 526225:GOBS_RS14655
uniprot id: D2S8N3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23795
gene id: 526225:GOBS_RS23795
uniprot id: D2S5Y4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

526225:GOBS RS07045
gene id: 526225:GOBS_RS07045
uniprot id: D2SBZ4
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS08150
gene id: 526225:GOBS_RS08150
uniprot id: D2SCY3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23500
gene id: 526225:GOBS_RS23500
uniprot id: D2S5S9
names: Similarity
messages: Belongs to the malate synthase family.

526225:GOBS RS20045
gene id: 526225:GOBS_RS20045
uniprot id: D2SEN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

526225:GOBS RS07170
gene id: 526225:GOBS_RS07170
uniprot id: D2SC19
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526225:GOBS RS13350
gene id: 526225:GOBS_RS13350
uniprot id: D2S6J1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

526225:GOBS RS07315
gene id: 526225:GOBS_RS07315
uniprot id: D2SC45
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23485
gene id: 526225:GOBS_RS23485
uniprot id: D2S5S6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS02650
gene id: 526225:GOBS_RS02650
uniprot id: D2S693
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

526225:GOBS RS04595
gene id: 526225:GOBS_RS04595
uniprot id: D2S944
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

526225:GOBS RS14575
gene id: 526225:GOBS_RS14575
uniprot id: D2S8L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS21260
gene id: 526225:GOBS_RS21260
uniprot id: D2SG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS13610
gene id: 526225:GOBS_RS13610
uniprot id: D2S6N9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526225:GOBS RS04660
gene id: 526225:GOBS_RS04660
uniprot id: D2S956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS15875
gene id: 526225:GOBS_RS15875
uniprot id: D2SA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

526225:GOBS RS10435
gene id: 526225:GOBS_RS10435
uniprot id: D2SFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

526225:GOBS RS13045
gene id: 526225:GOBS_RS13045
uniprot id: D2S6D2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

526225:GOBS RS20360
gene id: 526225:GOBS_RS20360
uniprot id: D2SEU2
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

526225:GOBS RS03225
gene id: 526225:GOBS_RS03225
uniprot id: D2S7C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

526225:GOBS RS06055
gene id: 526225:GOBS_RS06055
uniprot id: D2SAP7
names: Similarity
messages: Belongs to the CutA family.

526225:GOBS RS24380
gene id: 526225:GOBS_RS24380
uniprot id: D2S712
names: Similarity
messages: Belongs to the NodU/CmcH family.

526225:GOBS RS05600
gene id: 526225:GOBS_RS05600
uniprot id: D2SAF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

526225:GOBS RS07725
gene id: 526225:GOBS_RS07725
uniprot id: D2SCQ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS08950
gene id: 526225:GOBS_RS08950
uniprot id: D2SE55
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15435
gene id: 526225:GOBS_RS15435
uniprot id: D2S9G4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

526225:GOBS RS04680
gene id: 526225:GOBS_RS04680
uniprot id: D2S960
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

526225:GOBS RS16205
gene id: 526225:GOBS_RS16205
uniprot id: D2SA96
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

526225:GOBS RS06650
gene id: 526225:GOBS_RS06650
uniprot id: D2SBE0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

526225:GOBS RS21000
gene id: 526225:GOBS_RS21000
uniprot id: D2SFK4
names: Similarity
messages: Belongs to the PGI/PMI family.

526225:GOBS RS02320
gene id: 526225:GOBS_RS02320
uniprot id: D2S629
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

526225:GOBS RS21570
gene id: 526225:GOBS_RS21570
uniprot id: D2SG96
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

526225:GOBS RS21595
gene id: 526225:GOBS_RS21595
uniprot id: D2SGA0
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

526225:GOBS RS21205
gene id: 526225:GOBS_RS21205
uniprot id: D2SG29
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526225:GOBS RS08395
gene id: 526225:GOBS_RS08395
uniprot id: D2SDG2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS11040
gene id: 526225:GOBS_RS11040
uniprot id: D2SGU4
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22110
gene id: 526225:GOBS_RS22110
uniprot id: D2SHB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526225:GOBS RS21035
gene id: 526225:GOBS_RS21035
uniprot id: D2SFL1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

526225:GOBS RS06595
gene id: 526225:GOBS_RS06595
uniprot id: D2SBC9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS02730
gene id: 526225:GOBS_RS02730
uniprot id: D2S6A8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

526225:GOBS RS27800
gene id: 526225:GOBS_RS27800
uniprot id: D2SGD1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS25855
gene id: 526225:GOBS_RS25855
uniprot id: D2S710
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15115
gene id: 526225:GOBS_RS15115
uniprot id: D2S9A2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

526225:GOBS RS21575
gene id: 526225:GOBS_RS21575
uniprot id: D2SG97
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22905
gene id: 526225:GOBS_RS22905
uniprot id: D2S4S5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23705
gene id: 526225:GOBS_RS23705
uniprot id: D2S5W7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15625
gene id: 526225:GOBS_RS15625
uniprot id: D2S9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

526225:GOBS RS04765
gene id: 526225:GOBS_RS04765
uniprot id: D2S978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

526225:GOBS RS19675
gene id: 526225:GOBS_RS19675
uniprot id: D2SE32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

526225:GOBS RS01700
gene id: 526225:GOBS_RS01700
uniprot id: D2S525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS01955
gene id: 526225:GOBS_RS01955
uniprot id: D2S568
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS21965
gene id: 526225:GOBS_RS21965
uniprot id: D2SH84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

526225:GOBS RS13110
gene id: 526225:GOBS_RS13110
uniprot id: D2S6E4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

526225:GOBS RS22765
gene id: 526225:GOBS_RS22765
uniprot id: D2S4P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

526225:GOBS RS11330
gene id: 526225:GOBS_RS11330
uniprot id: D2SH03
names: Similarity
messages: Belongs to the proline racemase family.

526225:GOBS RS14755
gene id: 526225:GOBS_RS14755
uniprot id: D2S8P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

526225:GOBS RS10090
gene id: 526225:GOBS_RS10090
uniprot id: D2SF62
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

526225:GOBS RS12140
gene id: 526225:GOBS_RS12140
uniprot id: D2S4G2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

526225:GOBS RS20925
gene id: 526225:GOBS_RS20925
uniprot id: D2SFI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

526225:GOBS RS14995
gene id: 526225:GOBS_RS14995
uniprot id: D2S8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS09610
gene id: 526225:GOBS_RS09610
uniprot id: D2SEW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526225:GOBS RS00965
gene id: 526225:GOBS_RS00965
uniprot id: D2S3X3
names: Similarity
messages: Belongs to the allantoicase family.

526225:GOBS RS21510
gene id: 526225:GOBS_RS21510
uniprot id: D2SG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS22785
gene id: 526225:GOBS_RS22785
uniprot id: D2S4Q0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526225:GOBS RS08185
gene id: 526225:GOBS_RS08185
uniprot id: D2SCZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

526225:GOBS RS02075
gene id: 526225:GOBS_RS02075
uniprot id: D2S591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

526225:GOBS RS06260
gene id: 526225:GOBS_RS06260
uniprot id: D2SB66
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS21755
gene id: 526225:GOBS_RS21755
uniprot id: D2SGC9
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

526225:GOBS RS03885
gene id: 526225:GOBS_RS03885
uniprot id: D2S8C4
names: Subcellular Location Annotation
messages: Cytoplasm

526225:GOBS RS13230
gene id: 526225:GOBS_RS13230
uniprot id: D2S6G7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS04025
gene id: 526225:GOBS_RS04025
uniprot id: D2S8F3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS17845
gene id: 526225:GOBS_RS17845
uniprot id: D2SCB0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS11395
gene id: 526225:GOBS_RS11395
uniprot id: D2SH15
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

526225:GOBS RS18870
gene id: 526225:GOBS_RS18870
uniprot id: D2SD96
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS24020
gene id: 526225:GOBS_RS24020
uniprot id: D2S6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

526225:GOBS RS02485
gene id: 526225:GOBS_RS02485
uniprot id: D2S660
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS15240
gene id: 526225:GOBS_RS15240
uniprot id: D2S9C5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

526225:GOBS RS19545
gene id: 526225:GOBS_RS19545
uniprot id: D2SE07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

526225:GOBS RS11935
gene id: 526225:GOBS_RS11935
uniprot id: D2S4C0
names: Similarity
messages: Belongs to the DapA family.

526225:GOBS RS04375
gene id: 526225:GOBS_RS04375
uniprot id: D2S902
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

526225:GOBS RS10375
gene id: 526225:GOBS_RS10375
uniprot id: D2SFQ2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

526225:GOBS RS09305
gene id: 526225:GOBS_RS09305
uniprot id: D2SEC5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

526225:GOBS RS12155
gene id: 526225:GOBS_RS12155
uniprot id: D2S4G5
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

526225:GOBS RS21400
gene id: 526225:GOBS_RS21400
uniprot id: D2SG61
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

526225:GOBS RS14555
gene id: 526225:GOBS_RS14555
uniprot id: D2S8L3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

526225:GOBS RS00170
gene id: 526225:GOBS_RS00170
uniprot id: D2SGG2
names: Similarity
messages: Belongs to the UPF0749 family.

526225:GOBS RS23110
gene id: 526225:GOBS_RS23110
uniprot id: D2S4W3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22435
gene id: 526225:GOBS_RS22435
uniprot id: D2SHH6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

526225:GOBS RS04535
gene id: 526225:GOBS_RS04535
uniprot id: D2S932
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

526225:GOBS RS11100
gene id: 526225:GOBS_RS11100
uniprot id: D2SGV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

526225:GOBS RS13225
gene id: 526225:GOBS_RS13225
uniprot id: D2S6G6
names: Similarity
messages: Belongs to the thymidine kinase family.

526225:GOBS RS19185
gene id: 526225:GOBS_RS19185
uniprot id: D2SDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

526225:GOBS RS24075
gene id: 526225:GOBS_RS24075
uniprot id: D2S6V1
names: Similarity
messages: Belongs to the peptidase U62 family.

526225:GOBS RS15935
gene id: 526225:GOBS_RS15935
uniprot id: D2SA42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

526225:GOBS RS21750
gene id: 526225:GOBS_RS21750
uniprot id: D2SGC8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

526225:GOBS RS03530
gene id: 526225:GOBS_RS03530
uniprot id: D2S858
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS21955
gene id: 526225:GOBS_RS21955
uniprot id: D2SH82
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526225:GOBS RS06385
gene id: 526225:GOBS_RS06385
uniprot id: D2SB88
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

526225:GOBS RS20950
gene id: 526225:GOBS_RS20950
uniprot id: D2SFJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

526225:GOBS RS19745
gene id: 526225:GOBS_RS19745
uniprot id: D2SEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

526225:GOBS RS23345
gene id: 526225:GOBS_RS23345
uniprot id: D2S5P9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526225:GOBS RS19265
gene id: 526225:GOBS_RS19265
uniprot id: D2SDV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

526225:GOBS RS05340
gene id: 526225:GOBS_RS05340
uniprot id: D2S9X0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

526225:GOBS RS23560
gene id: 526225:GOBS_RS23560
uniprot id: D2S5U1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS25645
gene id: 526225:GOBS_RS25645
uniprot id: D2SCD0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

526225:GOBS RS18775
gene id: 526225:GOBS_RS18775
uniprot id: D2SD78
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

526225:GOBS RS06145
gene id: 526225:GOBS_RS06145
uniprot id: D2SB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

526225:GOBS RS04990
gene id: 526225:GOBS_RS04990
uniprot id: D2S9Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

526225:GOBS RS21010
gene id: 526225:GOBS_RS21010
uniprot id: D2SFK6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526225:GOBS RS23330
gene id: 526225:GOBS_RS23330
uniprot id: D2S5P5
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16445
gene id: 526225:GOBS_RS16445
uniprot id: D2SAS3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS08000
gene id: 526225:GOBS_RS08000
uniprot id: D2SCV2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

526225:GOBS RS00145
gene id: 526225:GOBS_RS00145
uniprot id: D2SGF8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

526225:GOBS RS18095
gene id: 526225:GOBS_RS18095
uniprot id: D2SCG3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS18055
gene id: 526225:GOBS_RS18055
uniprot id: D2SCF5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

526225:GOBS RS21395
gene id: 526225:GOBS_RS21395
uniprot id: D2SG60
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

526225:GOBS RS06075
gene id: 526225:GOBS_RS06075
uniprot id: D2SAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

526225:GOBS RS14325
gene id: 526225:GOBS_RS14325
uniprot id: D2S7U2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS19565
gene id: 526225:GOBS_RS19565
uniprot id: D2SE11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

526225:GOBS RS20995
gene id: 526225:GOBS_RS20995
uniprot id: D2SFK3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

526225:GOBS RS08520
gene id: 526225:GOBS_RS08520
uniprot id: D2SDI9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

526225:GOBS RS15395
gene id: 526225:GOBS_RS15395
uniprot id: D2S9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

526225:GOBS RS00860
gene id: 526225:GOBS_RS00860
uniprot id: D2S3V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

526225:GOBS RS19375
gene id: 526225:GOBS_RS19375
uniprot id: D2SDX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

526225:GOBS RS17140
gene id: 526225:GOBS_RS17140
uniprot id: D2SBJ0
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

526225:GOBS RS09255
gene id: 526225:GOBS_RS09255
uniprot id: D2SEB5
names: Similarity
messages: Belongs to the UPF0045 family.

526225:GOBS RS05330
gene id: 526225:GOBS_RS05330
uniprot id: D2S9W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

526225:GOBS RS24840
gene id: 526225:GOBS_RS24840
uniprot id: D2S815
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

526225:GOBS RS06085
gene id: 526225:GOBS_RS06085
uniprot id: D2SAQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

526225:GOBS RS03025
gene id: 526225:GOBS_RS03025
uniprot id: D2S785
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

526225:GOBS RS21890
gene id: 526225:GOBS_RS21890
uniprot id: D2SH69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

526225:GOBS RS01640
gene id: 526225:GOBS_RS01640
uniprot id: D2S514
names: Similarity
messages: Belongs to the LOG family.

526225:GOBS RS09285
gene id: 526225:GOBS_RS09285
uniprot id: D2SEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

526225:GOBS RS02820
gene id: 526225:GOBS_RS02820
uniprot id: D2S744
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526225:GOBS RS18545
gene id: 526225:GOBS_RS18545
uniprot id: D2SD32
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

526225:GOBS RS10635
gene id: 526225:GOBS_RS10635
uniprot id: D2SFV2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

526225:GOBS RS05005
gene id: 526225:GOBS_RS05005
uniprot id: D2S9Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

526225:GOBS RS14845
gene id: 526225:GOBS_RS14845
uniprot id: D2S8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

526225:GOBS RS01120
gene id: 526225:GOBS_RS01120
uniprot id: D2S404
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

526225:GOBS RS09465
gene id: 526225:GOBS_RS09465
uniprot id: D2SEF7
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

526225:GOBS RS03880
gene id: 526225:GOBS_RS03880
uniprot id: D2S8C3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

526225:GOBS RS17655
gene id: 526225:GOBS_RS17655
uniprot id: D2SBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

526225:GOBS RS08755
gene id: 526225:GOBS_RS08755
uniprot id: D2SDN5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS05520
gene id: 526225:GOBS_RS05520
uniprot id: D2SAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

526225:GOBS RS04120
gene id: 526225:GOBS_RS04120
uniprot id: D2S8H2
names: Similarity
messages: Belongs to the citrate synthase family.

526225:GOBS RS19155
gene id: 526225:GOBS_RS19155
uniprot id: D2SDT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526225:GOBS RS14300
gene id: 526225:GOBS_RS14300
uniprot id: D2S7T7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS09470
gene id: 526225:GOBS_RS09470
uniprot id: D2SEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

526225:GOBS RS03300
gene id: 526225:GOBS_RS03300
uniprot id: D2S7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

526225:GOBS RS09970
gene id: 526225:GOBS_RS09970
uniprot id: D2SF36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

526225:GOBS RS11600
gene id: 526225:GOBS_RS11600
uniprot id: D2S456
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10740
gene id: 526225:GOBS_RS10740
uniprot id: D2SFX3
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS07135
gene id: 526225:GOBS_RS07135
uniprot id: D2SC12
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS21180
gene id: 526225:GOBS_RS21180
uniprot id: D2SG24
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

526225:GOBS RS06155
gene id: 526225:GOBS_RS06155
uniprot id: D2SB47
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

526225:GOBS RS22260
gene id: 526225:GOBS_RS22260
uniprot id: D2SHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526225:GOBS RS21385
gene id: 526225:GOBS_RS21385
uniprot id: D2SG58
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

526225:GOBS RS20210
gene id: 526225:GOBS_RS20210
uniprot id: D2SER4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

526225:GOBS RS08070
gene id: 526225:GOBS_RS08070
uniprot id: D2SCW7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526225:GOBS RS05565
gene id: 526225:GOBS_RS05565
uniprot id: D2SAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

526225:GOBS RS23375
gene id: 526225:GOBS_RS23375
uniprot id: D2S5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

526225:GOBS RS17385
gene id: 526225:GOBS_RS17385
uniprot id: D2SBN6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16400
gene id: 526225:GOBS_RS16400
uniprot id: D2SAR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526225:GOBS RS19285
gene id: 526225:GOBS_RS19285
uniprot id: D2SDV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

526225:GOBS RS07780
gene id: 526225:GOBS_RS07780
uniprot id: D2SCR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

526225:GOBS RS23930
gene id: 526225:GOBS_RS23930
uniprot id: D2S6S3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

526225:GOBS RS15285
gene id: 526225:GOBS_RS15285
uniprot id: D2S9D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

526225:GOBS RS13300
gene id: 526225:GOBS_RS13300
uniprot id: D2S6I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

526225:GOBS RS22240
gene id: 526225:GOBS_RS22240
uniprot id: D2SHD7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

526225:GOBS RS14090
gene id: 526225:GOBS_RS14090
uniprot id: D2S7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family.
messages: Cytoplasm

526225:GOBS RS10055
gene id: 526225:GOBS_RS10055
uniprot id: D2SF54
names: Similarity
messages: Belongs to the GPI family.

526225:GOBS RS22075
gene id: 526225:GOBS_RS22075
uniprot id: D2SHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

526225:GOBS RS19760
gene id: 526225:GOBS_RS19760
uniprot id: D2SEH9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

526225:GOBS RS24900
gene id: 526225:GOBS_RS24900
uniprot id: D2S827
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526225:GOBS RS00045
gene id: 526225:GOBS_RS00045
uniprot id: D2SGD9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19600
gene id: 526225:GOBS_RS19600
uniprot id: D2SE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

526225:GOBS RS21835
gene id: 526225:GOBS_RS21835
uniprot id: D2SH58
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

526225:GOBS RS19790
gene id: 526225:GOBS_RS19790
uniprot id: D2SEI5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

526225:GOBS RS24765
gene id: 526225:GOBS_RS24765
uniprot id: D2S7Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

526225:GOBS RS20235
gene id: 526225:GOBS_RS20235
uniprot id: D2SER9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

526225:GOBS RS24580
gene id: 526225:GOBS_RS24580
uniprot id: D2S7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

526225:GOBS RS01000
gene id: 526225:GOBS_RS01000
uniprot id: D2S3Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

526225:GOBS RS04280
gene id: 526225:GOBS_RS04280
uniprot id: D2S8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

526225:GOBS RS20555
gene id: 526225:GOBS_RS20555
uniprot id: D2SFB4
names: Similarity
messages: Belongs to the cytochrome P450 family.

526225:GOBS RS08105
gene id: 526225:GOBS_RS08105
uniprot id: D2SCX4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

526225:GOBS RS21855
gene id: 526225:GOBS_RS21855
uniprot id: D2SH62
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

526225:GOBS RS10695
gene id: 526225:GOBS_RS10695
uniprot id: D2SFW4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

526225:GOBS RS22360
gene id: 526225:GOBS_RS22360
uniprot id: D2SHG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

526225:GOBS RS14640
gene id: 526225:GOBS_RS14640
uniprot id: D2S8N0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS16420
gene id: 526225:GOBS_RS16420
uniprot id: D2SAR8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

526225:GOBS RS11705
gene id: 526225:GOBS_RS11705
uniprot id: D2S475
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS21970
gene id: 526225:GOBS_RS21970
uniprot id: D2SH85
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

526225:GOBS RS06785
gene id: 526225:GOBS_RS06785
uniprot id: D2SBG4
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS10895
gene id: 526225:GOBS_RS10895
uniprot id: D2SGR7
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

526225:GOBS RS11775
gene id: 526225:GOBS_RS11775
uniprot id: D2S489
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS03850
gene id: 526225:GOBS_RS03850
uniprot id: D2S8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

526225:GOBS RS22910
gene id: 526225:GOBS_RS22910
uniprot id: D2S4S6
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS23390
gene id: 526225:GOBS_RS23390
uniprot id: D2S5Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

526225:GOBS RS24420
gene id: 526225:GOBS_RS24420
uniprot id: D2S719
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

526225:GOBS RS08595
gene id: 526225:GOBS_RS08595
uniprot id: D2SDK4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

526225:GOBS RS15070
gene id: 526225:GOBS_RS15070
uniprot id: D2S993
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526225:GOBS RS15180
gene id: 526225:GOBS_RS15180
uniprot id: D2S9B3
names: Similarity
messages: Belongs to the CdaR family.

526225:GOBS RS17435
gene id: 526225:GOBS_RS17435
uniprot id: D2SBP6
names: Similarity
messages: Belongs to the histone deacetylase family.

526225:GOBS RS19075
gene id: 526225:GOBS_RS19075
uniprot id: D2SDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS22205
gene id: 526225:GOBS_RS22205
uniprot id: D2SHD0
names: Similarity
messages: Belongs to the UPF0234 family.

526225:GOBS RS21960
gene id: 526225:GOBS_RS21960
uniprot id: D2SH83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

526225:GOBS RS04880
gene id: 526225:GOBS_RS04880
uniprot id: D2S9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

526225:GOBS RS19970
gene id: 526225:GOBS_RS19970
uniprot id: D2SEL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS00480
gene id: 526225:GOBS_RS00480
uniprot id: D2SGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

526225:GOBS RS15205
gene id: 526225:GOBS_RS15205
uniprot id: D2S9B8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

526225:GOBS RS14400
gene id: 526225:GOBS_RS14400
uniprot id: D2S8I4
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS08825
gene id: 526225:GOBS_RS08825
uniprot id: D2SDQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

526225:GOBS RS03330
gene id: 526225:GOBS_RS03330
uniprot id: D2S7E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526225:GOBS RS05370
gene id: 526225:GOBS_RS05370
uniprot id: D2S9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526225:GOBS RS13105
gene id: 526225:GOBS_RS13105
uniprot id: D2S6E3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

526225:GOBS RS02530
gene id: 526225:GOBS_RS02530
uniprot id: D2S669
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

526225:GOBS RS24680
gene id: 526225:GOBS_RS24680
uniprot id: D2S7Y3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

526225:GOBS RS00015
gene id: 526225:GOBS_RS00015
uniprot id: D2SGD3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the HIBADH-related family.

526225:GOBS RS06270
gene id: 526225:GOBS_RS06270
uniprot id: D2SB68
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS20195
gene id: 526225:GOBS_RS20195
uniprot id: D2SER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

526225:GOBS RS17735
gene id: 526225:GOBS_RS17735
uniprot id: D2SC88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

526225:GOBS RS06655
gene id: 526225:GOBS_RS06655
uniprot id: D2SBE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

526225:GOBS RS10755
gene id: 526225:GOBS_RS10755
uniprot id: D2SFX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

526225:GOBS RS10065
gene id: 526225:GOBS_RS10065
uniprot id: D2SF56
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

526225:GOBS RS21550
gene id: 526225:GOBS_RS21550
uniprot id: D2SG92
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS09480
gene id: 526225:GOBS_RS09480
uniprot id: D2SEG0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526225:GOBS RS27805
gene id: 526225:GOBS_RS27805
uniprot id: D2S4M6
names: Function
names: Similarity
messages: Belongs to the MurL family.
messages: Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.

526225:GOBS RS24030
gene id: 526225:GOBS_RS24030
uniprot id: D2S6U2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526225:GOBS RS16465
gene id: 526225:GOBS_RS16465
uniprot id: D2SAS7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

526225:GOBS RS08590
gene id: 526225:GOBS_RS08590
uniprot id: D2SDK3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

526225:GOBS RS04825
gene id: 526225:GOBS_RS04825
uniprot id: D2S9M0
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

526225:GOBS RS19980
gene id: 526225:GOBS_RS19980
uniprot id: D2SEL9
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS22290
gene id: 526225:GOBS_RS22290
uniprot id: D2SHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

526225:GOBS RS20270
gene id: 526225:GOBS_RS20270
uniprot id: D2SES6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

526225:GOBS RS00005
gene id: 526225:GOBS_RS00005
uniprot id: D2SFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

526225:GOBS RS13745
gene id: 526225:GOBS_RS13745
uniprot id: D2S7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

526225:GOBS RS22580
gene id: 526225:GOBS_RS22580
uniprot id: D2S4K8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526225:GOBS RS27985
gene id: 526225:GOBS_RS27985
uniprot id: D2S962
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19975
gene id: 526225:GOBS_RS19975
uniprot id: D2SEL8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

526225:GOBS RS24415
gene id: 526225:GOBS_RS24415
uniprot id: D2S718
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526225:GOBS RS02925
gene id: 526225:GOBS_RS02925
uniprot id: D2S766
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

526225:GOBS RS09045
gene id: 526225:GOBS_RS09045
uniprot id: D2SE73
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526225:GOBS RS03245
gene id: 526225:GOBS_RS03245
uniprot id: D2S7C6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526225:GOBS RS21745
gene id: 526225:GOBS_RS21745
uniprot id: D2SGC7
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS18990
gene id: 526225:GOBS_RS18990
uniprot id: D2SDB8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

526225:GOBS RS10900
gene id: 526225:GOBS_RS10900
uniprot id: D2SGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

526225:GOBS RS16535
gene id: 526225:GOBS_RS16535
uniprot id: D2SAU2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS16645
gene id: 526225:GOBS_RS16645
uniprot id: D2SAW3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

526225:GOBS RS06455
gene id: 526225:GOBS_RS06455
uniprot id: D2SBA1
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS07840
gene id: 526225:GOBS_RS07840
uniprot id: D2SCS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

526225:GOBS RS21925
gene id: 526225:GOBS_RS21925
uniprot id: D2SH76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

526225:GOBS RS01655
gene id: 526225:GOBS_RS01655
uniprot id: D2S516
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS11940
gene id: 526225:GOBS_RS11940
uniprot id: D2S4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

526225:GOBS RS18960
gene id: 526225:GOBS_RS18960
uniprot id: D2SDB2
names: Subcellular Location Annotation
messages: Membrane

526225:GOBS RS19730
gene id: 526225:GOBS_RS19730
uniprot id: D2SEH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

526225:GOBS RS05440
gene id: 526225:GOBS_RS05440
uniprot id: D2S9Z0
names: Similarity
messages: Belongs to the LOG family.

526225:GOBS RS17705
gene id: 526225:GOBS_RS17705
uniprot id: D2SC83
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

526225:GOBS RS10010
gene id: 526225:GOBS_RS10010
uniprot id: D2SF44
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

526225:GOBS RS01015
gene id: 526225:GOBS_RS01015
uniprot id: D2S3Y3
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

526225:GOBS RS07595
gene id: 526225:GOBS_RS07595
uniprot id: D2SCN3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526225:GOBS RS11750
gene id: 526225:GOBS_RS11750
uniprot id: D2S484
names: Similarity
messages: Belongs to the MQO family.

526225:GOBS RS22925
gene id: 526225:GOBS_RS22925
uniprot id: D2S4S9
names: Similarity
messages: Belongs to the asp23 family.

526225:GOBS RS16675
gene id: 526225:GOBS_RS16675
uniprot id: D2SAW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

526225:GOBS RS09425
gene id: 526225:GOBS_RS09425
uniprot id: D2SEE9
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

526225:GOBS RS12490
gene id: 526225:GOBS_RS12490
uniprot id: D2S5D6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

526225:GOBS RS04865
gene id: 526225:GOBS_RS04865
uniprot id: D2S9M8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

526225:GOBS RS19125
gene id: 526225:GOBS_RS19125
uniprot id: D2SDS9
names: Similarity
messages: Belongs to the FPG family.

526225:GOBS RS07805
gene id: 526225:GOBS_RS07805
uniprot id: D2SCR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

526225:GOBS RS00675
gene id: 526225:GOBS_RS00675
uniprot id: D2SGR2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

526225:GOBS RS13335
gene id: 526225:GOBS_RS13335
uniprot id: D2S6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane