523849:OCC RS04175
gene id: 523849:OCC_RS04175
uniprot id: H3ZM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

523849:OCC RS12140
gene id: 523849:OCC_RS12140
uniprot id: H3ZRC8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

523849:OCC RS09800
gene id: 523849:OCC_RS09800
uniprot id: H3ZK83
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS06200
gene id: 523849:OCC_RS06200
uniprot id: H3ZLU9
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09050
gene id: 523849:OCC_RS09050
uniprot id: H3ZPB1
names: Similarity
messages: Belongs to the HupF/HypC family.

523849:OCC RS06620
gene id: 523849:OCC_RS06620
uniprot id: H3ZMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

523849:OCC RS09205
gene id: 523849:OCC_RS09205
uniprot id: H3ZN33
names: Similarity
messages: Belongs to the UPF0252 family.

523849:OCC RS07485
gene id: 523849:OCC_RS07485
uniprot id: S5ZB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

523849:OCC RS06010
gene id: 523849:OCC_RS06010
uniprot id: H3ZNR3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

523849:OCC RS10685
gene id: 523849:OCC_RS10685
uniprot id: H3ZJT7
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

523849:OCC RS01610
gene id: 523849:OCC_RS01610
uniprot id: H3ZPL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

523849:OCC RS10755
gene id: 523849:OCC_RS10755
uniprot id: H3ZJV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

523849:OCC RS11235
gene id: 523849:OCC_RS11235
uniprot id: H3ZMD6
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

523849:OCC RS05465
gene id: 523849:OCC_RS05465
uniprot id: H3ZR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

523849:OCC RS11530
gene id: 523849:OCC_RS11530
uniprot id: H3ZKP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

523849:OCC RS05370
gene id: 523849:OCC_RS05370
uniprot id: H3ZRA1
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS06210
gene id: 523849:OCC_RS06210
uniprot id: H3ZLV1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

523849:OCC RS06750
gene id: 523849:OCC_RS06750
uniprot id: H3ZLR1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

523849:OCC RS00430
gene id: 523849:OCC_RS00430
uniprot id: H3ZLS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate kinase PfkC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
messages: Cytoplasm

523849:OCC RS00060
gene id: 523849:OCC_RS00060
uniprot id: H3ZK31
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

523849:OCC RS01095
gene id: 523849:OCC_RS01095
uniprot id: H3ZQP4
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

523849:OCC RS10720
gene id: 523849:OCC_RS10720
uniprot id: H3ZJU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS11460
gene id: 523849:OCC_RS11460
uniprot id: H3ZKQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS03270
gene id: 523849:OCC_RS03270
uniprot id: H3ZNN9
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09665
gene id: 523849:OCC_RS09665
uniprot id: H3ZKA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

523849:OCC RS11315
gene id: 523849:OCC_RS11315
uniprot id: H3ZKT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

523849:OCC RS00005
gene id: 523849:OCC_RS00005
uniprot id: H3ZK42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

523849:OCC RS08385
gene id: 523849:OCC_RS08385
uniprot id: H3ZNX8
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

523849:OCC RS03680
gene id: 523849:OCC_RS03680
uniprot id: H3ZQS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

523849:OCC RS01350
gene id: 523849:OCC_RS01350
uniprot id: H3ZPR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

523849:OCC RS11480
gene id: 523849:OCC_RS11480
uniprot id: H3ZKQ0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

523849:OCC RS02170
gene id: 523849:OCC_RS02170
uniprot id: O32462
names: Activity Regulation
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 57 family.
messages: Catalyzes the transglycosylation of maltooligosaccharides, yielding maltooligosaccharides of various lengths and glucose. Maltose and glucose can be used as acceptors in the transfer reaction.
messages: Expressed constitutively.
messages: Inhibited by p-chloromercuribenzoic acid, monoiodoacetic acid, mercury and nickel ions.
messages: homodimer.

523849:OCC RS00875
gene id: 523849:OCC_RS00875
uniprot id: H3ZLX9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

523849:OCC RS04545
gene id: 523849:OCC_RS04545
uniprot id: H3ZM06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

523849:OCC RS02685
gene id: 523849:OCC_RS02685
uniprot id: H3ZJY2
names: Similarity
messages: Belongs to the BtpA family.

523849:OCC RS00410
gene id: 523849:OCC_RS00410
uniprot id: H3ZLS7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

523849:OCC RS09320
gene id: 523849:OCC_RS09320
uniprot id: H3ZL63
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS11625
gene id: 523849:OCC_RS11625
uniprot id: H3ZKM5
names: Similarity
messages: Belongs to the peptidase S9C family.

523849:OCC RS02545
gene id: 523849:OCC_RS02545
uniprot id: H3ZMZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS01520
gene id: 523849:OCC_RS01520
uniprot id: H3ZPN2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

523849:OCC RS01730
gene id: 523849:OCC_RS01730
uniprot id: H3ZN48
names: Similarity
messages: Belongs to the peptidase U62 family.

523849:OCC RS03705
gene id: 523849:OCC_RS03705
uniprot id: H3ZQS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

523849:OCC RS04780
gene id: 523849:OCC_RS04780
uniprot id: H3ZLM6
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

523849:OCC RS06760
gene id: 523849:OCC_RS06760
uniprot id: H3ZLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

523849:OCC RS08760
gene id: 523849:OCC_RS08760
uniprot id: H3ZPG8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

523849:OCC RS04135
gene id: 523849:OCC_RS04135
uniprot id: H3ZNF5
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

523849:OCC RS06845
gene id: 523849:OCC_RS06845
uniprot id: H3ZRH6
names: Similarity
messages: Belongs to the UPF0216 family.

523849:OCC RS06515
gene id: 523849:OCC_RS06515
uniprot id: H3ZKD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

523849:OCC RS08480
gene id: 523849:OCC_RS08480
uniprot id: H3ZLB7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00370
gene id: 523849:OCC_RS00370
uniprot id: H3ZLT5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

523849:OCC RS01305
gene id: 523849:OCC_RS01305
uniprot id: H3ZPS5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

523849:OCC RS10165
gene id: 523849:OCC_RS10165
uniprot id: H3ZPX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

523849:OCC RS11515
gene id: 523849:OCC_RS11515
uniprot id: H3ZKP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

523849:OCC RS05830
gene id: 523849:OCC_RS05830
uniprot id: H3ZLW1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

523849:OCC RS07245
gene id: 523849:OCC_RS07245
uniprot id: H3ZMQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

523849:OCC RS01920
gene id: 523849:OCC_RS01920
uniprot id: H3ZKV3
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS07345
gene id: 523849:OCC_RS07345
uniprot id: H3ZMS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

523849:OCC RS00155
gene id: 523849:OCC_RS00155
uniprot id: H3ZK12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

523849:OCC RS02305
gene id: 523849:OCC_RS02305
uniprot id: H3ZLF1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

523849:OCC RS04295
gene id: 523849:OCC_RS04295
uniprot id: H3ZM55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

523849:OCC RS10190
gene id: 523849:OCC_RS10190
uniprot id: H3ZPX0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

523849:OCC RS03350
gene id: 523849:OCC_RS03350
uniprot id: H3ZNQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

523849:OCC RS10535
gene id: 523849:OCC_RS10535
uniprot id: H3ZMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

523849:OCC RS09825
gene id: 523849:OCC_RS09825
uniprot id: H3ZK78
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04040
gene id: 523849:OCC_RS04040
uniprot id: H3ZND6
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS07740
gene id: 523849:OCC_RS07740
uniprot id: H3ZQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

523849:OCC RS07600
gene id: 523849:OCC_RS07600
uniprot id: S5Z4F6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

523849:OCC RS08340
gene id: 523849:OCC_RS08340
uniprot id: H3ZNW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

523849:OCC RS07970
gene id: 523849:OCC_RS07970
uniprot id: H3ZQA9
names: Similarity
messages: Belongs to the aspartokinase family.

523849:OCC RS00905
gene id: 523849:OCC_RS00905
uniprot id: H3ZQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

523849:OCC RS06350
gene id: 523849:OCC_RS06350
uniprot id: H3ZKG7
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

523849:OCC RS09805
gene id: 523849:OCC_RS09805
uniprot id: Q9YGA7
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the glycogen phosphorylase family.
messages: Expressed constitutively.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Catalyzes the phospholytic cleavage of maltodextrins with a minimal chain length of five glucose residues to yield glucose-1-phosphate. Low activity with tetraose and no activity with triose and maltose. Long maltodextrins (8 to 15 glucose units), amylose and starch are not as good substrates as maltoheptaose.
messages: Trimer (at 25 degrees Celsius).

523849:OCC RS10300
gene id: 523849:OCC_RS10300
uniprot id: H3ZPV0
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS03310
gene id: 523849:OCC_RS03310
uniprot id: H3ZNP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS08295
gene id: 523849:OCC_RS08295
uniprot id: H3ZNV9
names: Similarity
messages: Belongs to the IMPACT family.

523849:OCC RS03090
gene id: 523849:OCC_RS03090
uniprot id: H3ZNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

523849:OCC RS09860
gene id: 523849:OCC_RS09860
uniprot id: H3ZK71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS04320
gene id: 523849:OCC_RS04320
uniprot id: H3ZM50
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

523849:OCC RS04825
gene id: 523849:OCC_RS04825
uniprot id: H3ZLL7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS08575
gene id: 523849:OCC_RS08575
uniprot id: H3ZP14
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

523849:OCC RS06635
gene id: 523849:OCC_RS06635
uniprot id: H3ZJP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

523849:OCC RS10910
gene id: 523849:OCC_RS10910
uniprot id: H3ZN24
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

523849:OCC RS00645
gene id: 523849:OCC_RS00645
uniprot id: H3ZP55
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

523849:OCC RS02410
gene id: 523849:OCC_RS02410
uniprot id: H3ZLD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

523849:OCC RS04435
gene id: 523849:OCC_RS04435
uniprot id: H3ZM27
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS07225
gene id: 523849:OCC_RS07225
uniprot id: H3ZMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

523849:OCC RS02270
gene id: 523849:OCC_RS02270
uniprot id: H3ZLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

523849:OCC RS02350
gene id: 523849:OCC_RS02350
uniprot id: H3ZLE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

523849:OCC RS04660
gene id: 523849:OCC_RS04660
uniprot id: H3ZM80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS00130
gene id: 523849:OCC_RS00130
uniprot id: H3ZK17
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS03190
gene id: 523849:OCC_RS03190
uniprot id: H3ZNM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

523849:OCC RS08235
gene id: 523849:OCC_RS08235
uniprot id: H3ZQ44
names: Similarity
messages: Belongs to the UPF0175 family.

523849:OCC RS02320
gene id: 523849:OCC_RS02320
uniprot id: H3ZLE8
names: Similarity
messages: Belongs to the arginase family.

523849:OCC RS06695
gene id: 523849:OCC_RS06695
uniprot id: H3ZL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

523849:OCC RS08535
gene id: 523849:OCC_RS08535
uniprot id: H3ZP06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

523849:OCC RS06285
gene id: 523849:OCC_RS06285
uniprot id: H3ZKI0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

523849:OCC RS01445
gene id: 523849:OCC_RS01445
uniprot id: H3ZPP7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

523849:OCC RS03530
gene id: 523849:OCC_RS03530
uniprot id: H3ZQV5
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS02145
gene id: 523849:OCC_RS02145
uniprot id: H3ZLI1
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

523849:OCC RS06085
gene id: 523849:OCC_RS06085
uniprot id: H3ZNS8
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10020
gene id: 523849:OCC_RS10020
uniprot id: H3ZL75
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

523849:OCC RS10125
gene id: 523849:OCC_RS10125
uniprot id: H3ZPY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

523849:OCC RS06955
gene id: 523849:OCC_RS06955
uniprot id: H3ZRJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

523849:OCC RS06080
gene id: 523849:OCC_RS06080
uniprot id: H3ZNS7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

523849:OCC RS06905
gene id: 523849:OCC_RS06905
uniprot id: H3ZRI8
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

523849:OCC RS05405
gene id: 523849:OCC_RS05405
uniprot id: H3ZR94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08885
gene id: 523849:OCC_RS08885
uniprot id: H3ZPE3
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

523849:OCC RS01550
gene id: 523849:OCC_RS01550
uniprot id: H3ZPM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS07825
gene id: 523849:OCC_RS07825
uniprot id: H3ZQ81
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS06700
gene id: 523849:OCC_RS06700
uniprot id: H3ZL40
names: Similarity
messages: Belongs to the MoaD family.

523849:OCC RS01620
gene id: 523849:OCC_RS01620
uniprot id: H3ZPL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the transamination of phenylalanine, tyrosine and tryptophan. Shows virtually no activity towards aspartic acid, alanine, valine or isoleucine.
messages: Homodimer.

523849:OCC RS09790
gene id: 523849:OCC_RS09790
uniprot id: H3ZK85
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

523849:OCC RS06580
gene id: 523849:OCC_RS06580
uniprot id: H3ZKC3
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

523849:OCC RS00095
gene id: 523849:OCC_RS00095
uniprot id: H3ZK24
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS07705
gene id: 523849:OCC_RS07705
uniprot id: H3ZJL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

523849:OCC RS06860
gene id: 523849:OCC_RS06860
uniprot id: H3ZRH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

523849:OCC RS01100
gene id: 523849:OCC_RS01100
uniprot id: H3ZQP5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

523849:OCC RS10635
gene id: 523849:OCC_RS10635
uniprot id: H3ZML8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

523849:OCC RS06330
gene id: 523849:OCC_RS06330
uniprot id: H3ZKH1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

523849:OCC RS03320
gene id: 523849:OCC_RS03320
uniprot id: H3ZNP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS08140
gene id: 523849:OCC_RS08140
uniprot id: H3ZQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

523849:OCC RS01415
gene id: 523849:OCC_RS01415
uniprot id: H3ZPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

523849:OCC RS07195
gene id: 523849:OCC_RS07195
uniprot id: H3ZRP5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

523849:OCC RS02465
gene id: 523849:OCC_RS02465
uniprot id: H3ZMY5
names: Similarity
messages: Belongs to the FUN14 family.

523849:OCC RS09300
gene id: 523849:OCC_RS09300
uniprot id: H3ZL66
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04670
gene id: 523849:OCC_RS04670
uniprot id: H3ZJJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

523849:OCC RS01180
gene id: 523849:OCC_RS01180
uniprot id: H3ZMG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

523849:OCC RS10080
gene id: 523849:OCC_RS10080
uniprot id: H3ZL87
names: Subunit
messages: Homotetramer.

523849:OCC RS10835
gene id: 523849:OCC_RS10835
uniprot id: H3ZJQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

523849:OCC RS02485
gene id: 523849:OCC_RS02485
uniprot id: H3ZMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

523849:OCC RS04785
gene id: 523849:OCC_RS04785
uniprot id: H3ZLM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

523849:OCC RS10475
gene id: 523849:OCC_RS10475
uniprot id: H3ZMI5
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS03305
gene id: 523849:OCC_RS03305
uniprot id: H3ZNP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS09955
gene id: 523849:OCC_RS09955
uniprot id: H3ZK52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS08630
gene id: 523849:OCC_RS08630
uniprot id: H3ZPJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

523849:OCC RS02315
gene id: 523849:OCC_RS02315
uniprot id: H3ZLE9
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Belongs to the SIS family. PHI subfamily.

523849:OCC RS11520
gene id: 523849:OCC_RS11520
uniprot id: H3ZKP2
names: Similarity
messages: Belongs to the UPF0201 family.

523849:OCC RS08390
gene id: 523849:OCC_RS08390
uniprot id: H3ZNX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

523849:OCC RS06380
gene id: 523849:OCC_RS06380
uniprot id: H3ZKG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

523849:OCC RS07495
gene id: 523849:OCC_RS07495
uniprot id: H3ZMV1
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00540
gene id: 523849:OCC_RS00540
uniprot id: H3ZQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

523849:OCC RS01880
gene id: 523849:OCC_RS01880
uniprot id: H3ZKW1
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

523849:OCC RS07270
gene id: 523849:OCC_RS07270
uniprot id: H3ZMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

523849:OCC RS02595
gene id: 523849:OCC_RS02595
uniprot id: H3ZJW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS11430
gene id: 523849:OCC_RS11430
uniprot id: H3ZKR0
names: Similarity
messages: Belongs to the AOR/FOR family.

523849:OCC RS09165
gene id: 523849:OCC_RS09165
uniprot id: H3ZP91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

523849:OCC RS01345
gene id: 523849:OCC_RS01345
uniprot id: H3ZPR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

523849:OCC RS09660
gene id: 523849:OCC_RS09660
uniprot id: H3ZKA9
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

523849:OCC RS00790
gene id: 523849:OCC_RS00790
uniprot id: H3ZP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

523849:OCC RS03295
gene id: 523849:OCC_RS03295
uniprot id: A8JYL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS02125
gene id: 523849:OCC_RS02125
uniprot id: H3ZJJ8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

523849:OCC RS10490
gene id: 523849:OCC_RS10490
uniprot id: H3ZMI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal-type GPI family.
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS07570
gene id: 523849:OCC_RS07570
uniprot id: H3ZMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS01795
gene id: 523849:OCC_RS01795
uniprot id: H3ZN61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

523849:OCC RS03040
gene id: 523849:OCC_RS03040
uniprot id: H3ZP85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

523849:OCC RS08180
gene id: 523849:OCC_RS08180
uniprot id: H3ZQ33
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

523849:OCC RS02060
gene id: 523849:OCC_RS02060
uniprot id: H3ZNJ4
names: Similarity
messages: Belongs to the class-I fumarase family.

523849:OCC RS02095
gene id: 523849:OCC_RS02095
uniprot id: Q56301
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

523849:OCC RS02625
gene id: 523849:OCC_RS02625
uniprot id: H3ZJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

523849:OCC RS11240
gene id: 523849:OCC_RS11240
uniprot id: H3ZMD7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

523849:OCC RS01840
gene id: 523849:OCC_RS01840
uniprot id: S5ZAW1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

523849:OCC RS03210
gene id: 523849:OCC_RS03210
uniprot id: H3ZNM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS04105
gene id: 523849:OCC_RS04105
uniprot id: H3ZNE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS09895
gene id: 523849:OCC_RS09895
uniprot id: H3ZK64
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS01820
gene id: 523849:OCC_RS01820
uniprot id: H3ZN66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS06360
gene id: 523849:OCC_RS06360
uniprot id: H3ZKG5
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS01045
gene id: 523849:OCC_RS01045
uniprot id: H3ZQN4
names: Similarity
messages: Belongs to the UPF0251 family.

523849:OCC RS08165
gene id: 523849:OCC_RS08165
uniprot id: H3ZQ29
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

523849:OCC RS07560
gene id: 523849:OCC_RS07560
uniprot id: H3ZMW4
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS08325
gene id: 523849:OCC_RS08325
uniprot id: H3ZNW5
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

523849:OCC RS09785
gene id: 523849:OCC_RS09785
uniprot id: H3ZK86
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09810
gene id: 523849:OCC_RS09810
uniprot id: H3ZK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

523849:OCC RS10430
gene id: 523849:OCC_RS10430
uniprot id: H3ZNH2
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

523849:OCC RS09380
gene id: 523849:OCC_RS09380
uniprot id: H3ZL52
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS11055
gene id: 523849:OCC_RS11055
uniprot id: H3ZMA2
names: Similarity
messages: Belongs to the peptidase U62 family.

523849:OCC RS01780
gene id: 523849:OCC_RS01780
uniprot id: H3ZN58
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

523849:OCC RS01860
gene id: 523849:OCC_RS01860
uniprot id: H3ZKW5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

523849:OCC RS01335
gene id: 523849:OCC_RS01335
uniprot id: H3ZPR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

523849:OCC RS11195
gene id: 523849:OCC_RS11195
uniprot id: H3ZMC9
names: Similarity
messages: Belongs to the UPF0235 family.

523849:OCC RS08950
gene id: 523849:OCC_RS08950
uniprot id: H3ZQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

523849:OCC RS01405
gene id: 523849:OCC_RS01405
uniprot id: H3ZPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

523849:OCC RS08065
gene id: 523849:OCC_RS08065
uniprot id: H3ZQB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

523849:OCC RS04535
gene id: 523849:OCC_RS04535
uniprot id: H3ZM08
names: Similarity
messages: Belongs to the SAICAR synthetase family.

523849:OCC RS00440
gene id: 523849:OCC_RS00440
uniprot id: H3ZLS1
names: Similarity
messages: Belongs to the MEMO1 family.

523849:OCC RS11490
gene id: 523849:OCC_RS11490
uniprot id: H3ZKP8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

523849:OCC RS06880
gene id: 523849:OCC_RS06880
uniprot id: H3ZRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

523849:OCC RS00330
gene id: 523849:OCC_RS00330
uniprot id: H3ZLU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

523849:OCC RS03525
gene id: 523849:OCC_RS03525
uniprot id: H3ZQV6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

523849:OCC RS01105
gene id: 523849:OCC_RS01105
uniprot id: H3ZQP6
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS08070
gene id: 523849:OCC_RS08070
uniprot id: H3ZQB8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

523849:OCC RS00575
gene id: 523849:OCC_RS00575
uniprot id: H3ZQZ5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

523849:OCC RS10025
gene id: 523849:OCC_RS10025
uniprot id: H3ZL76
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

523849:OCC RS08380
gene id: 523849:OCC_RS08380
uniprot id: H3ZNX7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS12055
gene id: 523849:OCC_RS12055
uniprot id: H3ZRE5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

523849:OCC RS10980
gene id: 523849:OCC_RS10980
uniprot id: H3ZMP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

523849:OCC RS08995
gene id: 523849:OCC_RS08995
uniprot id: H3ZQG8
names: Similarity
messages: Belongs to the UPF0248 family.

523849:OCC RS04555
gene id: 523849:OCC_RS04555
uniprot id: H3ZM04
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

523849:OCC RS01845
gene id: 523849:OCC_RS01845
uniprot id: H3ZKW7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

523849:OCC RS00915
gene id: 523849:OCC_RS00915
uniprot id: H3ZQK8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

523849:OCC RS11295
gene id: 523849:OCC_RS11295
uniprot id: H3ZKT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

523849:OCC RS03655
gene id: 523849:OCC_RS03655
uniprot id: H3ZQT2
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00110
gene id: 523849:OCC_RS00110
uniprot id: H3ZK21
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS01275
gene id: 523849:OCC_RS01275
uniprot id: H3ZMI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

523849:OCC RS02935
gene id: 523849:OCC_RS02935
uniprot id: Q7LYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

523849:OCC RS07930
gene id: 523849:OCC_RS07930
uniprot id: H3ZQA2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

523849:OCC RS01070
gene id: 523849:OCC_RS01070
uniprot id: H3ZQN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

523849:OCC RS03215
gene id: 523849:OCC_RS03215
uniprot id: H3ZNM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

523849:OCC RS00865
gene id: 523849:OCC_RS00865
uniprot id: H3ZLY1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

523849:OCC RS10360
gene id: 523849:OCC_RS10360
uniprot id: H3ZPT7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS05940
gene id: 523849:OCC_RS05940
uniprot id: H3ZN08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS03785
gene id: 523849:OCC_RS03785
uniprot id: H3ZQQ7
names: Similarity
messages: Belongs to the UPF0047 family.

523849:OCC RS02395
gene id: 523849:OCC_RS02395
uniprot id: H3ZLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

523849:OCC RS04060
gene id: 523849:OCC_RS04060
uniprot id: H3ZNE0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

523849:OCC RS07320
gene id: 523849:OCC_RS07320
uniprot id: H3ZMR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

523849:OCC RS11300
gene id: 523849:OCC_RS11300
uniprot id: H3ZKT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS06060
gene id: 523849:OCC_RS06060
uniprot id: H3ZNS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

523849:OCC RS06345
gene id: 523849:OCC_RS06345
uniprot id: H3ZKG8
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

523849:OCC RS07565
gene id: 523849:OCC_RS07565
uniprot id: H3ZMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS01490
gene id: 523849:OCC_RS01490
uniprot id: H3ZPN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

523849:OCC RS02990
gene id: 523849:OCC_RS02990
uniprot id: H3ZP77
names: Similarity
messages: Belongs to the enolase family.

523849:OCC RS03165
gene id: 523849:OCC_RS03165
uniprot id: H3ZNL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS11060
gene id: 523849:OCC_RS11060
uniprot id: H3ZMA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

523849:OCC RS04640
gene id: 523849:OCC_RS04640
uniprot id: H3ZM84
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

523849:OCC RS05220
gene id: 523849:OCC_RS05220
uniprot id: H3ZR17
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08265
gene id: 523849:OCC_RS08265
uniprot id: H3ZQ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

523849:OCC RS09770
gene id: 523849:OCC_RS09770
uniprot id: H3ZK88
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

523849:OCC RS08645
gene id: 523849:OCC_RS08645
uniprot id: H3ZPI9
names: Similarity
messages: Belongs to the RuvB family.

523849:OCC RS07180
gene id: 523849:OCC_RS07180
uniprot id: H3ZRP2
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

523849:OCC RS08010
gene id: 523849:OCC_RS08010
uniprot id: H3ZQB7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

523849:OCC RS08560
gene id: 523849:OCC_RS08560
uniprot id: H3ZLA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

523849:OCC RS08415
gene id: 523849:OCC_RS08415
uniprot id: H3ZNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS01625
gene id: 523849:OCC_RS01625
uniprot id: H3ZPL0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

523849:OCC RS06670
gene id: 523849:OCC_RS06670
uniprot id: H3ZJN5
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04665
gene id: 523849:OCC_RS04665
uniprot id: H3ZJJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

523849:OCC RS07155
gene id: 523849:OCC_RS07155
uniprot id: H3ZRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

523849:OCC RS03020
gene id: 523849:OCC_RS03020
uniprot id: H3ZP82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

523849:OCC RS05585
gene id: 523849:OCC_RS05585
uniprot id: H3ZR57
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

523849:OCC RS08750
gene id: 523849:OCC_RS08750
uniprot id: H3ZPH0
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS09655
gene id: 523849:OCC_RS09655
uniprot id: H3ZKB0
names: Function
messages: Probably involved in the biogenesis of the ribosome.

523849:OCC RS01250
gene id: 523849:OCC_RS01250
uniprot id: H3ZMH6
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00740
gene id: 523849:OCC_RS00740
uniprot id: H3ZP36
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS07980
gene id: 523849:OCC_RS07980
uniprot id: H3ZQB1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

523849:OCC RS08800
gene id: 523849:OCC_RS08800
uniprot id: H3ZPG1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

523849:OCC RS03015
gene id: 523849:OCC_RS03015
uniprot id: H3ZP81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

523849:OCC RS05875
gene id: 523849:OCC_RS05875
uniprot id: H3ZLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

523849:OCC RS04830
gene id: 523849:OCC_RS04830
uniprot id: H3ZLL6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

523849:OCC RS11440
gene id: 523849:OCC_RS11440
uniprot id: H3ZKQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

523849:OCC RS09135
gene id: 523849:OCC_RS09135
uniprot id: H3ZQJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

523849:OCC RS08240
gene id: 523849:OCC_RS08240
uniprot id: H3ZQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

523849:OCC RS11185
gene id: 523849:OCC_RS11185
uniprot id: H3ZMC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

523849:OCC RS03545
gene id: 523849:OCC_RS03545
uniprot id: H3ZQV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

523849:OCC RS04260
gene id: 523849:OCC_RS04260
uniprot id: H3ZM59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS11885
gene id: 523849:OCC_RS11885
uniprot id: H3ZL11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

523849:OCC RS08640
gene id: 523849:OCC_RS08640
uniprot id: H3ZPJ0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

523849:OCC RS10665
gene id: 523849:OCC_RS10665
uniprot id: H3ZMM4
names: Subcellular Location Annotation
messages: Cell membrane

523849:OCC RS01905
gene id: 523849:OCC_RS01905
uniprot id: H3ZKV6
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

523849:OCC RS05485
gene id: 523849:OCC_RS05485
uniprot id: H3ZR78
names: Similarity
messages: Belongs to the PstS family.

523849:OCC RS00930
gene id: 523849:OCC_RS00930
uniprot id: H3ZQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

523849:OCC RS11925
gene id: 523849:OCC_RS11925
uniprot id: H3ZL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

523849:OCC RS10705
gene id: 523849:OCC_RS10705
uniprot id: H3ZMN3
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10135
gene id: 523849:OCC_RS10135
uniprot id: H3ZPY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

523849:OCC RS10615
gene id: 523849:OCC_RS10615
uniprot id: H3ZML3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

523849:OCC RS01875
gene id: 523849:OCC_RS01875
uniprot id: H3ZKW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

523849:OCC RS04635
gene id: 523849:OCC_RS04635
uniprot id: H3ZM85
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

523849:OCC RS10420
gene id: 523849:OCC_RS10420
uniprot id: H3ZNH4
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10830
gene id: 523849:OCC_RS10830
uniprot id: H3ZJQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS02280
gene id: 523849:OCC_RS02280
uniprot id: H3ZLF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS06610
gene id: 523849:OCC_RS06610
uniprot id: H3ZME9
names: Similarity
messages: Belongs to the carbamate kinase family.

523849:OCC RS09245
gene id: 523849:OCC_RS09245
uniprot id: H3ZN41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

523849:OCC RS11890
gene id: 523849:OCC_RS11890
uniprot id: H3ZL10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08260
gene id: 523849:OCC_RS08260
uniprot id: H3ZQ49
names: Similarity
messages: Belongs to the MCM family.

523849:OCC RS06355
gene id: 523849:OCC_RS06355
uniprot id: H3ZKG6
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

523849:OCC RS00705
gene id: 523849:OCC_RS00705
uniprot id: H3ZP43
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

523849:OCC RS03830
gene id: 523849:OCC_RS03830
uniprot id: H3ZN93
names: Similarity
messages: Belongs to the TBP family.

523849:OCC RS05910
gene id: 523849:OCC_RS05910
uniprot id: H3ZLX5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

523849:OCC RS09755
gene id: 523849:OCC_RS09755
uniprot id: H3ZK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

523849:OCC RS04560
gene id: 523849:OCC_RS04560
uniprot id: H3ZM03
names: Similarity
messages: Belongs to the GARS family.

523849:OCC RS11580
gene id: 523849:OCC_RS11580
uniprot id: H3ZKN3
names: Similarity
messages: Belongs to the DEAD box helicase family.

523849:OCC RS09565
gene id: 523849:OCC_RS09565
uniprot id: H3ZKX1
names: Similarity
messages: Belongs to the UPF0212 family.

523849:OCC RS10660
gene id: 523849:OCC_RS10660
uniprot id: H3ZJT2
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS02230
gene id: 523849:OCC_RS02230
uniprot id: H3ZLG6
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

523849:OCC RS12145
gene id: 523849:OCC_RS12145
uniprot id: H3ZRC7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

523849:OCC RS06935
gene id: 523849:OCC_RS06935
uniprot id: H3ZRJ4
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

523849:OCC RS00610
gene id: 523849:OCC_RS00610
uniprot id: S6A4G2
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

523849:OCC RS09625
gene id: 523849:OCC_RS09625
uniprot id: H3ZKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

523849:OCC RS05150
gene id: 523849:OCC_RS05150
uniprot id: H3ZR03
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS06065
gene id: 523849:OCC_RS06065
uniprot id: H3ZNS4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

523849:OCC RS03875
gene id: 523849:OCC_RS03875
uniprot id: H3ZNA2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

523849:OCC RS06450
gene id: 523849:OCC_RS06450
uniprot id: H3ZKE7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

523849:OCC RS03100
gene id: 523849:OCC_RS03100
uniprot id: H3ZNK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS02370
gene id: 523849:OCC_RS02370
uniprot id: H3ZLD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS03985
gene id: 523849:OCC_RS03985
uniprot id: H3ZNC5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

523849:OCC RS00755
gene id: 523849:OCC_RS00755
uniprot id: H3ZP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

523849:OCC RS08565
gene id: 523849:OCC_RS08565
uniprot id: H3ZP12
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS10225
gene id: 523849:OCC_RS10225
uniprot id: H3ZPW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

523849:OCC RS02920
gene id: 523849:OCC_RS02920
uniprot id: S6A4H9
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10040
gene id: 523849:OCC_RS10040
uniprot id: H3ZL79
names: Similarity
messages: Belongs to the UPF0045 family.

523849:OCC RS04330
gene id: 523849:OCC_RS04330
uniprot id: H3ZM48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.

523849:OCC RS10680
gene id: 523849:OCC_RS10680
uniprot id: H3ZJT6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

523849:OCC RS01510
gene id: 523849:OCC_RS01510
uniprot id: H3ZPN4
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00825
gene id: 523849:OCC_RS00825
uniprot id: Q9C4M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS02245
gene id: 523849:OCC_RS02245
uniprot id: H3ZLG3
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

523849:OCC RS10595
gene id: 523849:OCC_RS10595
uniprot id: H3ZMK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

523849:OCC RS10940
gene id: 523849:OCC_RS10940
uniprot id: H3ZMP1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

523849:OCC RS05945
gene id: 523849:OCC_RS05945
uniprot id: H3ZN09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS08600
gene id: 523849:OCC_RS08600
uniprot id: H3ZP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

523849:OCC RS07555
gene id: 523849:OCC_RS07555
uniprot id: H3ZMW3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

523849:OCC RS07610
gene id: 523849:OCC_RS07610
uniprot id: H3ZJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

523849:OCC RS03185
gene id: 523849:OCC_RS03185
uniprot id: H3ZNM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS07945
gene id: 523849:OCC_RS07945
uniprot id: H3ZQA5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

523849:OCC RS10620
gene id: 523849:OCC_RS10620
uniprot id: H3ZJS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

523849:OCC RS05965
gene id: 523849:OCC_RS05965
uniprot id: H3ZN13
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS01765
gene id: 523849:OCC_RS01765
uniprot id: H3ZN55
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

523849:OCC RS04675
gene id: 523849:OCC_RS04675
uniprot id: H3ZJJ4
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

523849:OCC RS04750
gene id: 523849:OCC_RS04750
uniprot id: H3ZLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

523849:OCC RS09055
gene id: 523849:OCC_RS09055
uniprot id: H3ZPB0
names: Similarity
messages: Belongs to the HypD family.

523849:OCC RS08255
gene id: 523849:OCC_RS08255
uniprot id: H3ZQ48
names: Subcellular Location Annotation
messages: Nucleus

523849:OCC RS09440
gene id: 523849:OCC_RS09440
uniprot id: H3ZKZ7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS11600
gene id: 523849:OCC_RS11600
uniprot id: H3ZKM9
names: Similarity
messages: Belongs to the UPF0111 family.

523849:OCC RS00450
gene id: 523849:OCC_RS00450
uniprot id: H3ZLR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

523849:OCC RS00885
gene id: 523849:OCC_RS00885
uniprot id: H3ZLX7
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

523849:OCC RS02365
gene id: 523849:OCC_RS02365
uniprot id: H3ZLD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

523849:OCC RS00265
gene id: 523849:OCC_RS00265
uniprot id: H3ZJZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

523849:OCC RS02405
gene id: 523849:OCC_RS02405
uniprot id: H3ZLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

523849:OCC RS06305
gene id: 523849:OCC_RS06305
uniprot id: H3ZKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS04480
gene id: 523849:OCC_RS04480
uniprot id: H3ZM18
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

523849:OCC RS01935
gene id: 523849:OCC_RS01935
uniprot id: H3ZKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

523849:OCC RS06640
gene id: 523849:OCC_RS06640
uniprot id: H3ZJP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS09620
gene id: 523849:OCC_RS09620
uniprot id: H3ZKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

523849:OCC RS01970
gene id: 523849:OCC_RS01970
uniprot id: H3ZKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

523849:OCC RS11025
gene id: 523849:OCC_RS11025
uniprot id: H3ZM96
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

523849:OCC RS09360
gene id: 523849:OCC_RS09360
uniprot id: H3ZL55
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

523849:OCC RS02250
gene id: 523849:OCC_RS02250
uniprot id: H3ZLG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS03475
gene id: 523849:OCC_RS03475
uniprot id: H3ZQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

523849:OCC RS03155
gene id: 523849:OCC_RS03155
uniprot id: H3ZNL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS11645
gene id: 523849:OCC_RS11645
uniprot id: H3ZKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

523849:OCC RS07185
gene id: 523849:OCC_RS07185
uniprot id: H3ZRP3
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

523849:OCC RS02040
gene id: 523849:OCC_RS02040
uniprot id: H3ZNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

523849:OCC RS10995
gene id: 523849:OCC_RS10995
uniprot id: H3ZM90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

523849:OCC RS04425
gene id: 523849:OCC_RS04425
uniprot id: H3ZM29
names: Similarity
messages: Belongs to the RutC family.

523849:OCC RS03490
gene id: 523849:OCC_RS03490
uniprot id: H3ZQW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

523849:OCC RS11495
gene id: 523849:OCC_RS11495
uniprot id: H3ZKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

523849:OCC RS04495
gene id: 523849:OCC_RS04495
uniprot id: H3ZM15
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

523849:OCC RS01260
gene id: 523849:OCC_RS01260
uniprot id: H3ZMH8
names: Similarity
messages: Belongs to the proline racemase family.

523849:OCC RS05650
gene id: 523849:OCC_RS05650
uniprot id: H3ZR46
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

523849:OCC RS11065
gene id: 523849:OCC_RS11065
uniprot id: H3ZMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

523849:OCC RS02945
gene id: 523849:OCC_RS02945
uniprot id: Q7LYW7
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane
messages: Glycosylated.
messages: Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import. Binds maltose and trehalose.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).
messages: The protein assumes different conformations with different physical properties depending whether maltose or trehalose is bound to the protein.

523849:OCC RS08345
gene id: 523849:OCC_RS08345
uniprot id: H3ZNW9
names: Similarity
messages: Belongs to the UPF0145 family.

523849:OCC RS00050
gene id: 523849:OCC_RS00050
uniprot id: H3ZK33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

523849:OCC RS12005
gene id: 523849:OCC_RS12005
uniprot id: H3ZRF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

523849:OCC RS04835
gene id: 523849:OCC_RS04835
uniprot id: H3ZLL5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

523849:OCC RS04840
gene id: 523849:OCC_RS04840
uniprot id: H3ZLL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

523849:OCC RS08350
gene id: 523849:OCC_RS08350
uniprot id: H3ZNX1
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09335
gene id: 523849:OCC_RS09335
uniprot id: H3ZL60
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS02525
gene id: 523849:OCC_RS02525
uniprot id: H3ZMZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

523849:OCC RS06390
gene id: 523849:OCC_RS06390
uniprot id: H3ZKF9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

523849:OCC RS06130
gene id: 523849:OCC_RS06130
uniprot id: H3ZNT6
names: Subcellular Location Annotation
messages: Encapsulin nanocompartment

523849:OCC RS09225
gene id: 523849:OCC_RS09225
uniprot id: H3ZN37
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

523849:OCC RS06235
gene id: 523849:OCC_RS06235
uniprot id: H3ZKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS08665
gene id: 523849:OCC_RS08665
uniprot id: H3ZPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

523849:OCC RS04610
gene id: 523849:OCC_RS04610
uniprot id: H3ZLZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

523849:OCC RS10295
gene id: 523849:OCC_RS10295
uniprot id: H3ZPV1
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS01400
gene id: 523849:OCC_RS01400
uniprot id: H3ZPQ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

523849:OCC RS08000
gene id: 523849:OCC_RS08000
uniprot id: H3ZQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

523849:OCC RS06435
gene id: 523849:OCC_RS06435
uniprot id: H3ZKF0
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

523849:OCC RS04760
gene id: 523849:OCC_RS04760
uniprot id: H3ZLN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

523849:OCC RS05500
gene id: 523849:OCC_RS05500
uniprot id: H3ZR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS00860
gene id: 523849:OCC_RS00860
uniprot id: H3ZLY2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

523849:OCC RS10405
gene id: 523849:OCC_RS10405
uniprot id: H3ZNH7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

523849:OCC RS04990
gene id: 523849:OCC_RS04990
uniprot id: S6A4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

523849:OCC RS09385
gene id: 523849:OCC_RS09385
uniprot id: H3ZL51
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

523849:OCC RS09650
gene id: 523849:OCC_RS09650
uniprot id: H3ZKB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS07545
gene id: 523849:OCC_RS07545
uniprot id: H3ZMW1
names: Similarity
messages: Belongs to the AOR/FOR family.

523849:OCC RS02900
gene id: 523849:OCC_RS02900
uniprot id: H3ZNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS10305
gene id: 523849:OCC_RS10305
uniprot id: H3ZPU9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

523849:OCC RS01365
gene id: 523849:OCC_RS01365
uniprot id: H3ZPR3
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

523849:OCC RS05445
gene id: 523849:OCC_RS05445
uniprot id: H3ZR86
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04630
gene id: 523849:OCC_RS04630
uniprot id: H3ZM86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

523849:OCC RS06885
gene id: 523849:OCC_RS06885
uniprot id: H3ZRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS08040
gene id: 523849:OCC_RS08040
uniprot id: H3ZQC5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS04890
gene id: 523849:OCC_RS04890
uniprot id: H3ZLK4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

523849:OCC RS10860
gene id: 523849:OCC_RS10860
uniprot id: H3ZJQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 2 family.
messages: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

523849:OCC RS04210
gene id: 523849:OCC_RS04210
uniprot id: H3ZM69
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

523849:OCC RS09615
gene id: 523849:OCC_RS09615
uniprot id: H3ZKB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

523849:OCC RS07290
gene id: 523849:OCC_RS07290
uniprot id: H3ZMR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

523849:OCC RS02615
gene id: 523849:OCC_RS02615
uniprot id: H3ZJW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

523849:OCC RS09990
gene id: 523849:OCC_RS09990
uniprot id: H3ZK45
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04580
gene id: 523849:OCC_RS04580
uniprot id: H3ZLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

523849:OCC RS00400
gene id: 523849:OCC_RS00400
uniprot id: H3ZLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

523849:OCC RS02555
gene id: 523849:OCC_RS02555
uniprot id: H3ZN00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS00570
gene id: 523849:OCC_RS00570
uniprot id: H3ZQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

523849:OCC RS11475
gene id: 523849:OCC_RS11475
uniprot id: H3ZKQ1
names: Similarity
messages: Belongs to the UPF0111 family.

523849:OCC RS09815
gene id: 523849:OCC_RS09815
uniprot id: H3ZK80
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS05320
gene id: 523849:OCC_RS05320
uniprot id: H3ZR39
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS08095
gene id: 523849:OCC_RS08095
uniprot id: H3ZNU9
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

523849:OCC RS08830
gene id: 523849:OCC_RS08830
uniprot id: H3ZQD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

523849:OCC RS01900
gene id: 523849:OCC_RS01900
uniprot id: H3ZKV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08090
gene id: 523849:OCC_RS08090
uniprot id: H3ZNU8
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04400
gene id: 523849:OCC_RS04400
uniprot id: H3ZM34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

523849:OCC RS04215
gene id: 523849:OCC_RS04215
uniprot id: H3ZM68
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

523849:OCC RS11650
gene id: 523849:OCC_RS11650
uniprot id: H3ZKM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

523849:OCC RS03175
gene id: 523849:OCC_RS03175
uniprot id: H3ZNM0
names: Similarity
messages: Belongs to the SUI1 family.

523849:OCC RS05535
gene id: 523849:OCC_RS05535
uniprot id: H3ZR67
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS06300
gene id: 523849:OCC_RS06300
uniprot id: H3ZKH7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS02550
gene id: 523849:OCC_RS02550
uniprot id: H3ZMZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS03685
gene id: 523849:OCC_RS03685
uniprot id: H3ZQS6
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS11320
gene id: 523849:OCC_RS11320
uniprot id: H3ZKT2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS04070
gene id: 523849:OCC_RS04070
uniprot id: H3ZNE2
names: Function
names: Similarity
messages: Belongs to the 2-phosphoglycerate kinase family.
messages: Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.

523849:OCC RS03005
gene id: 523849:OCC_RS03005
uniprot id: H3ZP79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS00620
gene id: 523849:OCC_RS00620
uniprot id: H3ZP60
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

523849:OCC RS00070
gene id: 523849:OCC_RS00070
uniprot id: H3ZK29
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

523849:OCC RS09745
gene id: 523849:OCC_RS09745
uniprot id: H3ZK93
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

523849:OCC RS02925
gene id: 523849:OCC_RS02925
uniprot id: Q7LYW4
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transcriptional regulator TrmB family.
messages: Contains an N-terminal DNA-binding domain and a C-terminal sugar-binding domain.
messages: Homodimer.
messages: Inhibits transcription of the trehalose/maltose transport gene cluster (malE operon). Acts by binding to two different operator sequences in the promoter, preventing polymerase recruitment and transcription.
messages: Repressor activity is regulated by binding of sugars to TrmB. Binding of maltose and trehalose results in derepression of the malE operon. Maltose is much more effective (50-100 uM) than trehalose (2.5 mM).

523849:OCC RS03010
gene id: 523849:OCC_RS03010
uniprot id: H3ZP80
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

523849:OCC RS02065
gene id: 523849:OCC_RS02065
uniprot id: H3ZNJ5
names: Similarity
messages: Belongs to the class-I fumarase family.

523849:OCC RS00550
gene id: 523849:OCC_RS00550
uniprot id: H3ZQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

523849:OCC RS02975
gene id: 523849:OCC_RS02975
uniprot id: H3ZP74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08725
gene id: 523849:OCC_RS08725
uniprot id: H3ZPH5
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS02475
gene id: 523849:OCC_RS02475
uniprot id: H3ZMY7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

523849:OCC RS00365
gene id: 523849:OCC_RS00365
uniprot id: H3ZLT6
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

523849:OCC RS07750
gene id: 523849:OCC_RS07750
uniprot id: H3ZQ65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

523849:OCC RS01750
gene id: 523849:OCC_RS01750
uniprot id: H3ZN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

523849:OCC RS11255
gene id: 523849:OCC_RS11255
uniprot id: H3ZME0
names: Similarity
messages: Belongs to the MoaB/Mog family.

523849:OCC RS09645
gene id: 523849:OCC_RS09645
uniprot id: H3ZKB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS10710
gene id: 523849:OCC_RS10710
uniprot id: H3ZJU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS04345
gene id: 523849:OCC_RS04345
uniprot id: H3ZM45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

523849:OCC RS06645
gene id: 523849:OCC_RS06645
uniprot id: H3ZJP0
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS08170
gene id: 523849:OCC_RS08170
uniprot id: H3ZQ31
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

523849:OCC RS03565
gene id: 523849:OCC_RS03565
uniprot id: H3ZQU8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08135
gene id: 523849:OCC_RS08135
uniprot id: H3ZQ23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS00415
gene id: 523849:OCC_RS00415
uniprot id: H3ZLS6
names: Similarity
messages: Belongs to the SfsA family.

523849:OCC RS09850
gene id: 523849:OCC_RS09850
uniprot id: H3ZK73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
messages: Cell membrane
messages: Membrane

523849:OCC RS00510
gene id: 523849:OCC_RS00510
uniprot id: H3ZLY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS01755
gene id: 523849:OCC_RS01755
uniprot id: H3ZN53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

523849:OCC RS05960
gene id: 523849:OCC_RS05960
uniprot id: H3ZN12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS09890
gene id: 523849:OCC_RS09890
uniprot id: H3ZK65
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00745
gene id: 523849:OCC_RS00745
uniprot id: H3ZP35
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

523849:OCC RS01245
gene id: 523849:OCC_RS01245
uniprot id: H3ZMH5
names: Similarity
messages: Belongs to the proline racemase family.

523849:OCC RS05980
gene id: 523849:OCC_RS05980
uniprot id: H3ZN16
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS11525
gene id: 523849:OCC_RS11525
uniprot id: H3ZKP1
names: Similarity
messages: Belongs to the peptidase M24B family.

523849:OCC RS01595
gene id: 523849:OCC_RS01595
uniprot id: H3ZPL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

523849:OCC RS09315
gene id: 523849:OCC_RS09315
uniprot id: H3ZL64
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS08780
gene id: 523849:OCC_RS08780
uniprot id: H3ZPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

523849:OCC RS04935
gene id: 523849:OCC_RS04935
uniprot id: H3ZLJ5
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS06940
gene id: 523849:OCC_RS06940
uniprot id: H3ZRJ5
names: Similarity
messages: Belongs to the glutaredoxin family.

523849:OCC RS10185
gene id: 523849:OCC_RS10185
uniprot id: H3ZPX1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

523849:OCC RS00800
gene id: 523849:OCC_RS00800
uniprot id: H3ZP24
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

523849:OCC RS11470
gene id: 523849:OCC_RS11470
uniprot id: H3ZKQ2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

523849:OCC RS08740
gene id: 523849:OCC_RS08740
uniprot id: H3ZPH2
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS01810
gene id: 523849:OCC_RS01810
uniprot id: H3ZN64
names: Similarity
messages: Belongs to the PDCD5 family.

523849:OCC RS05435
gene id: 523849:OCC_RS05435
uniprot id: H3ZR88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

523849:OCC RS04700
gene id: 523849:OCC_RS04700
uniprot id: H3ZLP2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

523849:OCC RS04605
gene id: 523849:OCC_RS04605
uniprot id: H3ZLZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

523849:OCC RS04600
gene id: 523849:OCC_RS04600
uniprot id: H3ZLZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

523849:OCC RS00260
gene id: 523849:OCC_RS00260
uniprot id: H3ZJZ1
names: Similarity
messages: Belongs to the HypE family.

523849:OCC RS06850
gene id: 523849:OCC_RS06850
uniprot id: H3ZRH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

523849:OCC RS05880
gene id: 523849:OCC_RS05880
uniprot id: H3ZLW9
names: Subunit
messages: Homotetramer.

523849:OCC RS05995
gene id: 523849:OCC_RS05995
uniprot id: H3ZN19
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

523849:OCC RS02940
gene id: 523849:OCC_RS02940
uniprot id: O51924
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

523849:OCC RS07220
gene id: 523849:OCC_RS07220
uniprot id: H3ZMQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS05540
gene id: 523849:OCC_RS05540
uniprot id: H3ZR66
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04615
gene id: 523849:OCC_RS04615
uniprot id: H3ZM89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

523849:OCC RS02535
gene id: 523849:OCC_RS02535
uniprot id: H3ZMZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

523849:OCC RS04550
gene id: 523849:OCC_RS04550
uniprot id: H3ZM05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS08335
gene id: 523849:OCC_RS08335
uniprot id: H3ZNW7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

523849:OCC RS03195
gene id: 523849:OCC_RS03195
uniprot id: H3ZNM4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

523849:OCC RS10015
gene id: 523849:OCC_RS10015
uniprot id: H3ZL74
names: Similarity
messages: Belongs to the UPF0200 family.

523849:OCC RS01495
gene id: 523849:OCC_RS01495
uniprot id: H3ZPN7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

523849:OCC RS05480
gene id: 523849:OCC_RS05480
uniprot id: H3ZR79
names: Similarity
messages: Belongs to the alkaline phosphatase family.

523849:OCC RS05060
gene id: 523849:OCC_RS05060
uniprot id: H3ZN72
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10495
gene id: 523849:OCC_RS10495
uniprot id: H3ZMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

523849:OCC RS08285
gene id: 523849:OCC_RS08285
uniprot id: H3ZQ54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS00385
gene id: 523849:OCC_RS00385
uniprot id: H3ZLT2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

523849:OCC RS12110
gene id: 523849:OCC_RS12110
uniprot id: H3ZRD4
names: Similarity
messages: Belongs to the AOR/FOR family.

523849:OCC RS02520
gene id: 523849:OCC_RS02520
uniprot id: H3ZMZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS04130
gene id: 523849:OCC_RS04130
uniprot id: H3ZNF4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

523849:OCC RS01195
gene id: 523849:OCC_RS01195
uniprot id: H3ZMG5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

523849:OCC RS10170
gene id: 523849:OCC_RS10170
uniprot id: H3ZPX4
names: Similarity
messages: Belongs to the UPF0179 family.

523849:OCC RS03080
gene id: 523849:OCC_RS03080
uniprot id: H3ZNK1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

523849:OCC RS11305
gene id: 523849:OCC_RS11305
uniprot id: H3ZKT5
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

523849:OCC RS10580
gene id: 523849:OCC_RS10580
uniprot id: H3ZJR5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

523849:OCC RS12030
gene id: 523849:OCC_RS12030
uniprot id: Q56304
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homohexamer.

523849:OCC RS09390
gene id: 523849:OCC_RS09390
uniprot id: H3ZL50
names: Similarity
messages: Belongs to the peptidase U62 family.

523849:OCC RS09420
gene id: 523849:OCC_RS09420
uniprot id: H3ZL44
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS02630
gene id: 523849:OCC_RS02630
uniprot id: H3ZJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

523849:OCC RS02530
gene id: 523849:OCC_RS02530
uniprot id: H3ZMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

523849:OCC RS06190
gene id: 523849:OCC_RS06190
uniprot id: H3ZLU8
names: Similarity
messages: Belongs to the serpin family.

523849:OCC RS11565
gene id: 523849:OCC_RS11565
uniprot id: H3ZKN5
names: Similarity
messages: Belongs to the UPF0282 family.

523849:OCC RS02235
gene id: 523849:OCC_RS02235
uniprot id: H3ZLG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

523849:OCC RS06920
gene id: 523849:OCC_RS06920
uniprot id: H3ZRJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

523849:OCC RS05955
gene id: 523849:OCC_RS05955
uniprot id: H3ZN11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS04385
gene id: 523849:OCC_RS04385
uniprot id: H3ZM37
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

523849:OCC RS06115
gene id: 523849:OCC_RS06115
uniprot id: H3ZNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

523849:OCC RS05055
gene id: 523849:OCC_RS05055
uniprot id: S5ZB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

523849:OCC RS04230
gene id: 523849:OCC_RS04230
uniprot id: H3ZM65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

523849:OCC RS09865
gene id: 523849:OCC_RS09865
uniprot id: H3ZK70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS03635
gene id: 523849:OCC_RS03635
uniprot id: H3ZQT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS06825
gene id: 523849:OCC_RS06825
uniprot id: H3ZRH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

523849:OCC RS11870
gene id: 523849:OCC_RS11870
uniprot id: H3ZL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

523849:OCC RS00040
gene id: 523849:OCC_RS00040
uniprot id: H3ZK35
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

523849:OCC RS06650
gene id: 523849:OCC_RS06650
uniprot id: H3ZJN9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

523849:OCC RS08110
gene id: 523849:OCC_RS08110
uniprot id: H3ZNV2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

523849:OCC RS02035
gene id: 523849:OCC_RS02035
uniprot id: H3ZNI9
names: Similarity
messages: Belongs to the UPF0166 family.

523849:OCC RS07540
gene id: 523849:OCC_RS07540
uniprot id: H3ZMW0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

523849:OCC RS04030
gene id: 523849:OCC_RS04030
uniprot id: H3ZND4
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS03605
gene id: 523849:OCC_RS03605
uniprot id: H3ZQU1
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

523849:OCC RS03135
gene id: 523849:OCC_RS03135
uniprot id: H3ZNL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS08675
gene id: 523849:OCC_RS08675
uniprot id: H3ZPI3
names: Similarity
messages: Belongs to the ZPR1 family.

523849:OCC RS10775
gene id: 523849:OCC_RS10775
uniprot id: H3ZJV6
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS06365
gene id: 523849:OCC_RS06365
uniprot id: H3ZKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

523849:OCC RS03075
gene id: 523849:OCC_RS03075
uniprot id: H3ZNK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

523849:OCC RS09885
gene id: 523849:OCC_RS09885
uniprot id: H3ZK66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS07760
gene id: 523849:OCC_RS07760
uniprot id: H3ZQ67
names: Subunit
messages: Homodimer.

523849:OCC RS09310
gene id: 523849:OCC_RS09310
uniprot id: P84820
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS09730
gene id: 523849:OCC_RS09730
uniprot id: H3ZK96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS04315
gene id: 523849:OCC_RS04315
uniprot id: H3ZM51
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

523849:OCC RS09945
gene id: 523849:OCC_RS09945
uniprot id: H3ZK54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS02355
gene id: 523849:OCC_RS02355
uniprot id: H3ZLE1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

523849:OCC RS03650
gene id: 523849:OCC_RS03650
uniprot id: H3ZQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS03110
gene id: 523849:OCC_RS03110
uniprot id: H3ZNK7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

523849:OCC RS01515
gene id: 523849:OCC_RS01515
uniprot id: H3ZPN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

523849:OCC RS08825
gene id: 523849:OCC_RS08825
uniprot id: H3ZPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS09725
gene id: 523849:OCC_RS09725
uniprot id: H3ZK97
names: Subcellular Location Annotation
messages: Cytoplasm

523849:OCC RS04465
gene id: 523849:OCC_RS04465
uniprot id: H3ZM22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

523849:OCC RS10340
gene id: 523849:OCC_RS10340
uniprot id: H3ZPU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the transamination of phenylalanine, tyrosine and tryptophan. Shows virtually no activity towards aspartic acid, alanine, valine or isoleucine.
messages: Homodimer.

523849:OCC RS08920
gene id: 523849:OCC_RS08920
uniprot id: H3ZQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

523849:OCC RS00270
gene id: 523849:OCC_RS00270
uniprot id: H3ZJY9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

523849:OCC RS08705
gene id: 523849:OCC_RS08705
uniprot id: H3ZPH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

523849:OCC RS10805
gene id: 523849:OCC_RS10805
uniprot id: H3ZJP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

523849:OCC RS08420
gene id: 523849:OCC_RS08420
uniprot id: H3ZNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

523849:OCC RS02340
gene id: 523849:OCC_RS02340
uniprot id: H3ZLE4
names: Similarity
messages: Belongs to the UPF0292 family.

523849:OCC RS01630
gene id: 523849:OCC_RS01630
uniprot id: H3ZPK9
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

523849:OCC RS08660
gene id: 523849:OCC_RS08660
uniprot id: H3ZPI6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

523849:OCC RS08945
gene id: 523849:OCC_RS08945
uniprot id: H3ZPD1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

523849:OCC RS03095
gene id: 523849:OCC_RS03095
uniprot id: H3ZNK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

523849:OCC RS04190
gene id: 523849:OCC_RS04190
uniprot id: H3ZM73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

523849:OCC RS03535
gene id: 523849:OCC_RS03535
uniprot id: H3ZQV4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

523849:OCC RS06400
gene id: 523849:OCC_RS06400
uniprot id: H3ZKF7
names: Similarity
messages: Belongs to the UPF0273 family.

523849:OCC RS08765
gene id: 523849:OCC_RS08765
uniprot id: H3ZPG7
names: Similarity
messages: Belongs to the UPF0127 family.

523849:OCC RS12050
gene id: 523849:OCC_RS12050
uniprot id: H3ZRE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

523849:OCC RS03895
gene id: 523849:OCC_RS03895
uniprot id: H3ZNA6
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10120
gene id: 523849:OCC_RS10120
uniprot id: H3ZPY3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

523849:OCC RS01190
gene id: 523849:OCC_RS01190
uniprot id: H3ZMG4
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

523849:OCC RS04655
gene id: 523849:OCC_RS04655
uniprot id: H3ZM81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

523849:OCC RS05885
gene id: 523849:OCC_RS05885
uniprot id: H3ZLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

523849:OCC RS09575
gene id: 523849:OCC_RS09575
uniprot id: H3ZKW9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

523849:OCC RS00505
gene id: 523849:OCC_RS00505
uniprot id: H3ZLY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS00815
gene id: 523849:OCC_RS00815
uniprot id: H3ZP21
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS07265
gene id: 523849:OCC_RS07265
uniprot id: H3ZMQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

523849:OCC RS08930
gene id: 523849:OCC_RS08930
uniprot id: O07883
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

523849:OCC RS11355
gene id: 523849:OCC_RS11355
uniprot id: H3ZKS4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

523849:OCC RS08370
gene id: 523849:OCC_RS08370
uniprot id: H3ZNX5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

523849:OCC RS09330
gene id: 523849:OCC_RS09330
uniprot id: H3ZL61
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

523849:OCC RS06230
gene id: 523849:OCC_RS06230
uniprot id: H3ZKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS04170
gene id: 523849:OCC_RS04170
uniprot id: H3ZM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

523849:OCC RS06385
gene id: 523849:OCC_RS06385
uniprot id: H3ZKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

523849:OCC RS04530
gene id: 523849:OCC_RS04530
uniprot id: H3ZM09
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

523849:OCC RS02985
gene id: 523849:OCC_RS02985
uniprot id: H3ZP76
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

523849:OCC RS11085
gene id: 523849:OCC_RS11085
uniprot id: H3ZMA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS11405
gene id: 523849:OCC_RS11405
uniprot id: H3ZKR5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

523849:OCC RS01310
gene id: 523849:OCC_RS01310
uniprot id: H3ZPS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS05630
gene id: 523849:OCC_RS05630
uniprot id: H3ZR50
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

523849:OCC RS04240
gene id: 523849:OCC_RS04240
uniprot id: H3ZM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

523849:OCC RS05285
gene id: 523849:OCC_RS05285
uniprot id: H3ZR32
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS00010
gene id: 523849:OCC_RS00010
uniprot id: H3ZK41
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

523849:OCC RS10950
gene id: 523849:OCC_RS10950
uniprot id: H3ZMP3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS11415
gene id: 523849:OCC_RS11415
uniprot id: H3ZKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

523849:OCC RS04120
gene id: 523849:OCC_RS04120
uniprot id: H3ZNF2
names: Similarity
messages: Belongs to the thymidylate kinase family.

523849:OCC RS10335
gene id: 523849:OCC_RS10335
uniprot id: H3ZPU2
names: Similarity
messages: Belongs to the HypE family.

523849:OCC RS00925
gene id: 523849:OCC_RS00925
uniprot id: H3ZQL0
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

523849:OCC RS02540
gene id: 523849:OCC_RS02540
uniprot id: H3ZMZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

523849:OCC RS02635
gene id: 523849:OCC_RS02635
uniprot id: H3ZJX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

523849:OCC RS07790
gene id: 523849:OCC_RS07790
uniprot id: H3ZQ74
names: Similarity
messages: Belongs to the UPF0047 family.

523849:OCC RS01185
gene id: 523849:OCC_RS01185
uniprot id: H3ZMG3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

523849:OCC RS03515
gene id: 523849:OCC_RS03515
uniprot id: H3ZQV8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

523849:OCC RS09735
gene id: 523849:OCC_RS09735
uniprot id: H3ZK95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS04650
gene id: 523849:OCC_RS04650
uniprot id: H3ZM82
names: Similarity
messages: Belongs to the SAICAR synthetase family.

523849:OCC RS01645
gene id: 523849:OCC_RS01645
uniprot id: H3ZPK7
names: Similarity
messages: Belongs to the UPF0252 family.

523849:OCC RS04390
gene id: 523849:OCC_RS04390
uniprot id: H3ZM36
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

523849:OCC RS09670
gene id: 523849:OCC_RS09670
uniprot id: H3ZKA7
names: Similarity
messages: Belongs to the UPF0440 family.

523849:OCC RS07975
gene id: 523849:OCC_RS07975
uniprot id: H3ZQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

523849:OCC RS06310
gene id: 523849:OCC_RS06310
uniprot id: H3ZKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS03595
gene id: 523849:OCC_RS03595
uniprot id: H3ZQU3
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09045
gene id: 523849:OCC_RS09045
uniprot id: H3ZPB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

523849:OCC RS01395
gene id: 523849:OCC_RS01395
uniprot id: H3ZPQ7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

523849:OCC RS09240
gene id: 523849:OCC_RS09240
uniprot id: H3ZN39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

523849:OCC RS00230
gene id: 523849:OCC_RS00230
uniprot id: H3ZJZ7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

523849:OCC RS02120
gene id: 523849:OCC_RS02120
uniprot id: H3ZJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

523849:OCC RS02360
gene id: 523849:OCC_RS02360
uniprot id: H3ZLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

523849:OCC RS09875
gene id: 523849:OCC_RS09875
uniprot id: H3ZK68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS06725
gene id: 523849:OCC_RS06725
uniprot id: H3ZL35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

523849:OCC RS11375
gene id: 523849:OCC_RS11375
uniprot id: H3ZKS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

523849:OCC RS03540
gene id: 523849:OCC_RS03540
uniprot id: H3ZQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

523849:OCC RS11095
gene id: 523849:OCC_RS11095
uniprot id: H3ZMB0
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS05750
gene id: 523849:OCC_RS05750
uniprot id: H3ZRB4
names: Similarity
messages: Belongs to the UPF0107 family.

523849:OCC RS10730
gene id: 523849:OCC_RS10730
uniprot id: H3ZMN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS02600
gene id: 523849:OCC_RS02600
uniprot id: H3ZJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

523849:OCC RS09960
gene id: 523849:OCC_RS09960
uniprot id: H3ZK51
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09200
gene id: 523849:OCC_RS09200
uniprot id: H3ZN32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

523849:OCC RS00200
gene id: 523849:OCC_RS00200
uniprot id: H3ZK03
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

523849:OCC RS09265
gene id: 523849:OCC_RS09265
uniprot id: S6A4M0
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

523849:OCC RS02995
gene id: 523849:OCC_RS02995
uniprot id: H3ZP78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS03465
gene id: 523849:OCC_RS03465
uniprot id: H3ZQW9
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

523849:OCC RS00175
gene id: 523849:OCC_RS00175
uniprot id: H3ZK08
names: Similarity
messages: Belongs to the acylphosphatase family.

523849:OCC RS08250
gene id: 523849:OCC_RS08250
uniprot id: H3ZQ47
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

523849:OCC RS04100
gene id: 523849:OCC_RS04100
uniprot id: H3ZNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

523849:OCC RS07815
gene id: 523849:OCC_RS07815
uniprot id: H3ZQ79
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

523849:OCC RS02255
gene id: 523849:OCC_RS02255
uniprot id: H3ZLG1
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

523849:OCC RS12070
gene id: 523849:OCC_RS12070
uniprot id: H3ZRE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

523849:OCC RS04055
gene id: 523849:OCC_RS04055
uniprot id: H3ZND9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS08595
gene id: 523849:OCC_RS08595
uniprot id: H3ZP17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

523849:OCC RS04355
gene id: 523849:OCC_RS04355
uniprot id: H3ZM43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

523849:OCC RS02610
gene id: 523849:OCC_RS02610
uniprot id: H3ZJW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

523849:OCC RS09975
gene id: 523849:OCC_RS09975
uniprot id: H3ZK48
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

523849:OCC RS02335
gene id: 523849:OCC_RS02335
uniprot id: H3ZLE5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

523849:OCC RS06095
gene id: 523849:OCC_RS06095
uniprot id: H3ZNT0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

523849:OCC RS04695
gene id: 523849:OCC_RS04695
uniprot id: H3ZLP3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

523849:OCC RS06335
gene id: 523849:OCC_RS06335
uniprot id: H3ZKH0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

523849:OCC RS06320
gene id: 523849:OCC_RS06320
uniprot id: H3ZKH3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

523849:OCC RS04790
gene id: 523849:OCC_RS04790
uniprot id: H3ZLM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

523849:OCC RS01145
gene id: 523849:OCC_RS01145
uniprot id: H3ZMF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

523849:OCC RS05545
gene id: 523849:OCC_RS05545
uniprot id: H3ZR65
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

523849:OCC RS07465
gene id: 523849:OCC_RS07465
uniprot id: H3ZMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

523849:OCC RS11225
gene id: 523849:OCC_RS11225
uniprot id: H3ZMD4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

523849:OCC RS10920
gene id: 523849:OCC_RS10920
uniprot id: H3ZN22
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

523849:OCC RS09105
gene id: 523849:OCC_RS09105
uniprot id: H3ZQI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

523849:OCC RS10435
gene id: 523849:OCC_RS10435
uniprot id: H3ZNH1
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

523849:OCC RS03070
gene id: 523849:OCC_RS03070
uniprot id: H3ZNJ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

523849:OCC RS04380
gene id: 523849:OCC_RS04380
uniprot id: H3ZM38
names: Similarity
messages: Belongs to the HerA family.

523849:OCC RS02130
gene id: 523849:OCC_RS02130
uniprot id: H3ZJJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

523849:OCC RS01830
gene id: 523849:OCC_RS01830
uniprot id: H3ZN68
names: Similarity
messages: Belongs to the peptidase C56 family.

523849:OCC RS10760
gene id: 523849:OCC_RS10760
uniprot id: H3ZJV3
names: Similarity
messages: Belongs to the UPF0045 family.

523849:OCC RS02620
gene id: 523849:OCC_RS02620
uniprot id: H3ZJW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

523849:OCC RS03120
gene id: 523849:OCC_RS03120
uniprot id: H3ZNK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS00425
gene id: 523849:OCC_RS00425
uniprot id: H3ZLS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

523849:OCC RS09845
gene id: 523849:OCC_RS09845
uniprot id: H3ZK74
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

523849:OCC RS03315
gene id: 523849:OCC_RS03315
uniprot id: H3ZNP8
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS08495
gene id: 523849:OCC_RS08495
uniprot id: H3ZLB4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

523849:OCC RS00085
gene id: 523849:OCC_RS00085
uniprot id: H3ZK26
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

523849:OCC RS10345
gene id: 523849:OCC_RS10345
uniprot id: H3ZPU0
names: Similarity
messages: Belongs to the NodU/CmcH family.

523849:OCC RS08515
gene id: 523849:OCC_RS08515
uniprot id: H3ZLB0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

523849:OCC RS02215
gene id: 523849:OCC_RS02215
uniprot id: H3ZLG9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

523849:OCC RS11410
gene id: 523849:OCC_RS11410
uniprot id: H3ZKR4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS11435
gene id: 523849:OCC_RS11435
uniprot id: H3ZKQ9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

523849:OCC RS07255
gene id: 523849:OCC_RS07255
uniprot id: H3ZMQ7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS00115
gene id: 523849:OCC_RS00115
uniprot id: H3ZK20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

523849:OCC RS07235
gene id: 523849:OCC_RS07235
uniprot id: H3ZMQ4
names: Similarity
messages: Belongs to the TrpF family.

523849:OCC RS06105
gene id: 523849:OCC_RS06105
uniprot id: H3ZNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS03900
gene id: 523849:OCC_RS03900
uniprot id: H3ZNA7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS03205
gene id: 523849:OCC_RS03205
uniprot id: H3ZNM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

523849:OCC RS09220
gene id: 523849:OCC_RS09220
uniprot id: H3ZN36
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

523849:OCC RS04775
gene id: 523849:OCC_RS04775
uniprot id: H3ZLM7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

523849:OCC RS07995
gene id: 523849:OCC_RS07995
uniprot id: H3ZQB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

523849:OCC RS01540
gene id: 523849:OCC_RS01540
uniprot id: H3ZPM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

523849:OCC RS01535
gene id: 523849:OCC_RS01535
uniprot id: H3ZPM9
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

523849:OCC RS10675
gene id: 523849:OCC_RS10675
uniprot id: H3ZJT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

523849:OCC RS03180
gene id: 523849:OCC_RS03180
uniprot id: H3ZNM1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

523849:OCC RS11455
gene id: 523849:OCC_RS11455
uniprot id: H3ZKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

523849:OCC RS03140
gene id: 523849:OCC_RS03140
uniprot id: H3ZNL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS08115
gene id: 523849:OCC_RS08115
uniprot id: H3ZNV3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

523849:OCC RS03105
gene id: 523849:OCC_RS03105
uniprot id: H3ZNK6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

523849:OCC RS03035
gene id: 523849:OCC_RS03035
uniprot id: H3ZP84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS04245
gene id: 523849:OCC_RS04245
uniprot id: H3ZM62
names: Similarity
messages: Belongs to the DtxR/MntR family.

523849:OCC RS04165
gene id: 523849:OCC_RS04165
uniprot id: H3ZM78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

523849:OCC RS07280
gene id: 523849:OCC_RS07280
uniprot id: H3ZMR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

523849:OCC RS11710
gene id: 523849:OCC_RS11710
uniprot id: H3ZKK8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

523849:OCC RS04445
gene id: 523849:OCC_RS04445
uniprot id: H3ZM25
names: Similarity
messages: Belongs to the UPF0252 family.

523849:OCC RS08025
gene id: 523849:OCC_RS08025
uniprot id: H3ZQC8
names: Similarity
messages: Belongs to the HypE family.

523849:OCC RS05255
gene id: 523849:OCC_RS05255
uniprot id: H3ZR24
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS11265
gene id: 523849:OCC_RS11265
uniprot id: S5ZI24
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

523849:OCC RS04770
gene id: 523849:OCC_RS04770
uniprot id: H3ZLM8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

523849:OCC RS10735
gene id: 523849:OCC_RS10735
uniprot id: H3ZJU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS01995
gene id: 523849:OCC_RS01995
uniprot id: H3ZNI1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

523849:OCC RS11895
gene id: 523849:OCC_RS11895
uniprot id: H3ZL09
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

523849:OCC RS08085
gene id: 523849:OCC_RS08085
uniprot id: H3ZNU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

523849:OCC RS04570
gene id: 523849:OCC_RS04570
uniprot id: H3ZM01
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

523849:OCC RS01800
gene id: 523849:OCC_RS01800
uniprot id: H3ZN62
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

523849:OCC RS03055
gene id: 523849:OCC_RS03055
uniprot id: H3ZP88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

523849:OCC RS10425
gene id: 523849:OCC_RS10425
uniprot id: H3ZNH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

523849:OCC RS10905
gene id: 523849:OCC_RS10905
uniprot id: H3ZN25
names: Similarity
messages: Belongs to the DDAH family.

523849:OCC RS03085
gene id: 523849:OCC_RS03085
uniprot id: H3ZNK2
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09930
gene id: 523849:OCC_RS09930
uniprot id: H3ZK57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS05755
gene id: 523849:OCC_RS05755
uniprot id: H3ZRB3
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04690
gene id: 523849:OCC_RS04690
uniprot id: H3ZLP4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

523849:OCC RS02025
gene id: 523849:OCC_RS02025
uniprot id: H3ZNI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS03150
gene id: 523849:OCC_RS03150
uniprot id: H3ZNL5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

523849:OCC RS10895
gene id: 523849:OCC_RS10895
uniprot id: H3ZN27
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

523849:OCC RS08635
gene id: 523849:OCC_RS08635
uniprot id: H3ZPJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

523849:OCC RS01600
gene id: 523849:OCC_RS01600
uniprot id: H3ZPL5
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

523849:OCC RS11875
gene id: 523849:OCC_RS11875
uniprot id: H3ZL13
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

523849:OCC RS05470
gene id: 523849:OCC_RS05470
uniprot id: H3ZR81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

523849:OCC RS04200
gene id: 523849:OCC_RS04200
uniprot id: H3ZM71
names: Cofactor
messages: Binds 1 zinc ion per subunit.

523849:OCC RS03160
gene id: 523849:OCC_RS03160
uniprot id: H3ZNL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

523849:OCC RS00080
gene id: 523849:OCC_RS00080
uniprot id: H3ZK27
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

523849:OCC RS08015
gene id: 523849:OCC_RS08015
uniprot id: H3ZLZ3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

523849:OCC RS04145
gene id: 523849:OCC_RS04145
uniprot id: H3ZNF6
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

523849:OCC RS02390
gene id: 523849:OCC_RS02390
uniprot id: H3ZLD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

523849:OCC RS02260
gene id: 523849:OCC_RS02260
uniprot id: H3ZLG0
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

523849:OCC RS02345
gene id: 523849:OCC_RS02345
uniprot id: H3ZLE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

523849:OCC RS01385
gene id: 523849:OCC_RS01385
uniprot id: H3ZPQ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

523849:OCC RS02605
gene id: 523849:OCC_RS02605
uniprot id: H3ZJW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

523849:OCC RS06375
gene id: 523849:OCC_RS06375
uniprot id: H3ZKG2
names: Function
messages: Part of a potassium transport system.

523849:OCC RS02160
gene id: 523849:OCC_RS02160
uniprot id: H3ZLH8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

523849:OCC RS06770
gene id: 523849:OCC_RS06770
uniprot id: H3ZLR5
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09185
gene id: 523849:OCC_RS09185
uniprot id: H3ZQK3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

523849:OCC RS02080
gene id: 523849:OCC_RS02080
uniprot id: Q56303
names: Activity Regulation
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A low amount of aldehyde ferredoxin oxidoreductase activity has been observed.
messages: Belongs to the AOR/FOR family.
messages: Binds 1 W-bis(molybdopterin guanine dinucleotide) (W-bis-MGD) cofactor per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the oxidation of C1-C3 aldehydes. Involved in peptides fermentation.
messages: Homotetramer.
messages: Inhibited by arsenite, iodoacetate and cyanide.

523849:OCC RS00360
gene id: 523849:OCC_RS00360
uniprot id: H3ZLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

523849:OCC RS02895
gene id: 523849:OCC_RS02895
uniprot id: H3ZNG0
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS10800
gene id: 523849:OCC_RS10800
uniprot id: H3ZJP6
names: Similarity
messages: Belongs to the UPF0173 family.

523849:OCC RS06250
gene id: 523849:OCC_RS06250
uniprot id: H3ZKI7
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

523849:OCC RS01960
gene id: 523849:OCC_RS01960
uniprot id: H3ZKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

523849:OCC RS03200
gene id: 523849:OCC_RS03200
uniprot id: H3ZNM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

523849:OCC RS09750
gene id: 523849:OCC_RS09750
uniprot id: H3ZK92
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

523849:OCC RS07880
gene id: 523849:OCC_RS07880
uniprot id: H3ZQ92
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

523849:OCC RS11715
gene id: 523849:OCC_RS11715
uniprot id: H3ZKK7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

523849:OCC RS02950
gene id: 523849:OCC_RS02950
uniprot id: H3ZP68
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

523849:OCC RS07315
gene id: 523849:OCC_RS07315
uniprot id: H3ZMR7
names: Subcellular Location Annotation
messages: Cytoplasm

523849:OCC RS03130
gene id: 523849:OCC_RS03130
uniprot id: H3ZNL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

523849:OCC RS06225
gene id: 523849:OCC_RS06225
uniprot id: H3ZKJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

523849:OCC RS10540
gene id: 523849:OCC_RS10540
uniprot id: H3ZMJ7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS09605
gene id: 523849:OCC_RS09605
uniprot id: H3ZKB8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

523849:OCC RS04115
gene id: 523849:OCC_RS04115
uniprot id: H3ZNF1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

523849:OCC RS03115
gene id: 523849:OCC_RS03115
uniprot id: H3ZNK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

523849:OCC RS00165
gene id: 523849:OCC_RS00165
uniprot id: H3ZK10
names: Similarity
messages: Belongs to the UPF0215 family.

523849:OCC RS02265
gene id: 523849:OCC_RS02265
uniprot id: H3ZLF9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

523849:OCC RS05735
gene id: 523849:OCC_RS05735
uniprot id: H3ZRB7
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04065
gene id: 523849:OCC_RS04065
uniprot id: H3ZNE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
messages: Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
messages: Cytoplasm

523849:OCC RS12000
gene id: 523849:OCC_RS12000
uniprot id: H3ZRF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

523849:OCC RS11270
gene id: 523849:OCC_RS11270
uniprot id: H3ZMX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

523849:OCC RS10840
gene id: 523849:OCC_RS10840
uniprot id: H3ZJQ4
names: Similarity
messages: Belongs to the peptidase S9C family.

523849:OCC RS01985
gene id: 523849:OCC_RS01985
uniprot id: H3ZNH9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

523849:OCC RS09600
gene id: 523849:OCC_RS09600
uniprot id: H3ZKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

523849:OCC RS11400
gene id: 523849:OCC_RS11400
uniprot id: H3ZKR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

523849:OCC RS00880
gene id: 523849:OCC_RS00880
uniprot id: H3ZLX8
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS03145
gene id: 523849:OCC_RS03145
uniprot id: H3ZNL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

523849:OCC RS11640
gene id: 523849:OCC_RS11640
uniprot id: H3ZKM2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

523849:OCC RS01200
gene id: 523849:OCC_RS01200
uniprot id: H3ZMG6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

523849:OCC RS01945
gene id: 523849:OCC_RS01945
uniprot id: H3ZKU9
names: Similarity
messages: Belongs to the peptidase S49 family.

523849:OCC RS02930
gene id: 523849:OCC_RS02930
uniprot id: Q7LYW5
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: By maltose, less efficiently by trehalose, and even less efficiently by sucrose.
messages: Homodimer.
messages: Synthesizes trehalose from ADP-glucose and glucose. Has a much lower activity toward UDP-glucose and GDP-glucose. The reaction is reversible, the equilibrium strongly favors trehalose synthesis.

523849:OCC RS03340
gene id: 523849:OCC_RS03340
uniprot id: H3ZNQ3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

523849:OCC RS00515
gene id: 523849:OCC_RS00515
uniprot id: H3ZLY6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

523849:OCC RS10195
gene id: 523849:OCC_RS10195
uniprot id: H3ZPW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

523849:OCC RS00445
gene id: 523849:OCC_RS00445
uniprot id: H3ZLS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

523849:OCC RS06820
gene id: 523849:OCC_RS06820
uniprot id: H3ZRH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

523849:OCC RS11010
gene id: 523849:OCC_RS11010
uniprot id: H3ZM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

523849:OCC RS05110
gene id: 523849:OCC_RS05110
uniprot id: H3ZN80
names: Similarity
messages: Belongs to the UPF0175 family.

523849:OCC RS03395
gene id: 523849:OCC_RS03395
uniprot id: H3ZQY3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

523849:OCC RS03265
gene id: 523849:OCC_RS03265
uniprot id: A8JYL0
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS11465
gene id: 523849:OCC_RS11465
uniprot id: H3ZKQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

523849:OCC RS07920
gene id: 523849:OCC_RS07920
uniprot id: H3ZQA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

523849:OCC RS04430
gene id: 523849:OCC_RS04430
uniprot id: H3ZM28
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS04795
gene id: 523849:OCC_RS04795
uniprot id: P77992
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

523849:OCC RS03240
gene id: 523849:OCC_RS03240
uniprot id: Q9UWQ8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

523849:OCC RS02000
gene id: 523849:OCC_RS02000
uniprot id: H3ZNI2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

523849:OCC RS05505
gene id: 523849:OCC_RS05505
uniprot id: H3ZR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

523849:OCC RS09935
gene id: 523849:OCC_RS09935
uniprot id: H3ZK56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

523849:OCC RS09920
gene id: 523849:OCC_RS09920
uniprot id: H3ZK59
names: Subcellular Location Annotation
messages: Membrane

523849:OCC RS07550
gene id: 523849:OCC_RS07550
uniprot id: H3ZMW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

523849:OCC RS01085
gene id: 523849:OCC_RS01085
uniprot id: H3ZQP2
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

523849:OCC RS09345
gene id: 523849:OCC_RS09345
uniprot id: H3ZL58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

523849:OCC RS05335
gene id: 523849:OCC_RS05335
uniprot id: H3ZRA6
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.