521010:BBIDN127 RS03920
gene id: 521010:BBIDN127_RS03920
uniprot id: G0AMM0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

521010:BBIDN127 RS06600
gene id: 521010:BBIDN127_RS06600
uniprot id: G0APA7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

521010:BBIDN127 RS06530
gene id: 521010:BBIDN127_RS06530
uniprot id: G0AP90
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

521010:BBIDN127 RS03265
gene id: 521010:BBIDN127_RS03265
uniprot id: G0AM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

521010:BBIDN127 RS02350
gene id: 521010:BBIDN127_RS02350
uniprot id: G0ALS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS03245
gene id: 521010:BBIDN127_RS03245
uniprot id: G0AM90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

521010:BBIDN127 RS04315
gene id: 521010:BBIDN127_RS04315
uniprot id: G0AMU8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

521010:BBIDN127 RS03490
gene id: 521010:BBIDN127_RS03490
uniprot id: G0AMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

521010:BBIDN127 RS02030
gene id: 521010:BBIDN127_RS02030
uniprot id: G0ALL5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02330
gene id: 521010:BBIDN127_RS02330
uniprot id: G0ALR6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

521010:BBIDN127 RS02570
gene id: 521010:BBIDN127_RS02570
uniprot id: G0ALW4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

521010:BBIDN127 RS00255
gene id: 521010:BBIDN127_RS00255
uniprot id: G0AKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

521010:BBIDN127 RS03460
gene id: 521010:BBIDN127_RS03460
uniprot id: G0AMD2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

521010:BBIDN127 RS03205
gene id: 521010:BBIDN127_RS03205
uniprot id: G0AM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521010:BBIDN127 RS01645
gene id: 521010:BBIDN127_RS01645
uniprot id: G0ALE2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

521010:BBIDN127 RS00420
gene id: 521010:BBIDN127_RS00420
uniprot id: G0AKP9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00250
gene id: 521010:BBIDN127_RS00250
uniprot id: G0AKL4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02425
gene id: 521010:BBIDN127_RS02425
uniprot id: G0ALT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

521010:BBIDN127 RS03510
gene id: 521010:BBIDN127_RS03510
uniprot id: G0AME2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

521010:BBIDN127 RS01785
gene id: 521010:BBIDN127_RS01785
uniprot id: G0ALH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02175
gene id: 521010:BBIDN127_RS02175
uniprot id: G0ALN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

521010:BBIDN127 RS02200
gene id: 521010:BBIDN127_RS02200
uniprot id: G0ALP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02770
gene id: 521010:BBIDN127_RS02770
uniprot id: G0AM02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

521010:BBIDN127 RS00950
gene id: 521010:BBIDN127_RS00950
uniprot id: G0AL07
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

521010:BBIDN127 RS03100
gene id: 521010:BBIDN127_RS03100
uniprot id: G0AM63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

521010:BBIDN127 RS02480
gene id: 521010:BBIDN127_RS02480
uniprot id: G0ALU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

521010:BBIDN127 RS05125
gene id: 521010:BBIDN127_RS05125
uniprot id: G0ANB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS04245
gene id: 521010:BBIDN127_RS04245
uniprot id: G0AMT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

521010:BBIDN127 RS05325
gene id: 521010:BBIDN127_RS05325
uniprot id: G0ANF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS01495
gene id: 521010:BBIDN127_RS01495
uniprot id: G0ALB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

521010:BBIDN127 RS03440
gene id: 521010:BBIDN127_RS03440
uniprot id: G0AMC9
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

521010:BBIDN127 RS03105
gene id: 521010:BBIDN127_RS03105
uniprot id: G0AM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

521010:BBIDN127 RS00310
gene id: 521010:BBIDN127_RS00310
uniprot id: G0AKM6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

521010:BBIDN127 RS03990
gene id: 521010:BBIDN127_RS03990
uniprot id: G0AMN3
names: Similarity
messages: Belongs to the Skp family.

521010:BBIDN127 RS01435
gene id: 521010:BBIDN127_RS01435
uniprot id: G0AL99
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

521010:BBIDN127 RS00785
gene id: 521010:BBIDN127_RS00785
uniprot id: G0AKX4
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01830
gene id: 521010:BBIDN127_RS01830
uniprot id: G0ALH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02395
gene id: 521010:BBIDN127_RS02395
uniprot id: G0ALS9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

521010:BBIDN127 RS04320
gene id: 521010:BBIDN127_RS04320
uniprot id: G0AMU9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS01750
gene id: 521010:BBIDN127_RS01750
uniprot id: G0ALG3
names: Similarity
messages: Belongs to the peptidase S41A family.

521010:BBIDN127 RS00240
gene id: 521010:BBIDN127_RS00240
uniprot id: G0AKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

521010:BBIDN127 RS02465
gene id: 521010:BBIDN127_RS02465
uniprot id: G0ALU3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

521010:BBIDN127 RS01620
gene id: 521010:BBIDN127_RS01620
uniprot id: G0ALD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS02125
gene id: 521010:BBIDN127_RS02125
uniprot id: G0ALM9
names: Similarity
messages: Belongs to the IMPACT family.

521010:BBIDN127 RS04360
gene id: 521010:BBIDN127_RS04360
uniprot id: G0AMV7
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01370
gene id: 521010:BBIDN127_RS01370
uniprot id: G0AL86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

521010:BBIDN127 RS04025
gene id: 521010:BBIDN127_RS04025
uniprot id: G0AMP0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

521010:BBIDN127 RS01215
gene id: 521010:BBIDN127_RS01215
uniprot id: G0AL55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

521010:BBIDN127 RS02300
gene id: 521010:BBIDN127_RS02300
uniprot id: G0ALR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

521010:BBIDN127 RS01180
gene id: 521010:BBIDN127_RS01180
uniprot id: G0AL49
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS01890
gene id: 521010:BBIDN127_RS01890
uniprot id: G0ALJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521010:BBIDN127 RS03465
gene id: 521010:BBIDN127_RS03465
uniprot id: G0AMD3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

521010:BBIDN127 RS01075
gene id: 521010:BBIDN127_RS01075
uniprot id: G0AL28
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00275
gene id: 521010:BBIDN127_RS00275
uniprot id: G0AKL9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

521010:BBIDN127 RS00070
gene id: 521010:BBIDN127_RS00070
uniprot id: G0AKH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

521010:BBIDN127 RS02975
gene id: 521010:BBIDN127_RS02975
uniprot id: G0AM43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02595
gene id: 521010:BBIDN127_RS02595
uniprot id: G0ALW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS04165
gene id: 521010:BBIDN127_RS04165
uniprot id: G0AMR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

521010:BBIDN127 RS03300
gene id: 521010:BBIDN127_RS03300
uniprot id: G0AMA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

521010:BBIDN127 RS03680
gene id: 521010:BBIDN127_RS03680
uniprot id: G0AMH3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

521010:BBIDN127 RS00625
gene id: 521010:BBIDN127_RS00625
uniprot id: G0AKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

521010:BBIDN127 RS03735
gene id: 521010:BBIDN127_RS03735
uniprot id: G0AMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521010:BBIDN127 RS01445
gene id: 521010:BBIDN127_RS01445
uniprot id: G0ALA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

521010:BBIDN127 RS03875
gene id: 521010:BBIDN127_RS03875
uniprot id: G0AML1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

521010:BBIDN127 RS00260
gene id: 521010:BBIDN127_RS00260
uniprot id: G0AKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

521010:BBIDN127 RS03915
gene id: 521010:BBIDN127_RS03915
uniprot id: G0AML9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

521010:BBIDN127 RS04250
gene id: 521010:BBIDN127_RS04250
uniprot id: G0AMT6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

521010:BBIDN127 RS00150
gene id: 521010:BBIDN127_RS00150
uniprot id: G0AKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

521010:BBIDN127 RS02825
gene id: 521010:BBIDN127_RS02825
uniprot id: G0AM12
names: Similarity
messages: Belongs to the UMP kinase family.

521010:BBIDN127 RS06265
gene id: 521010:BBIDN127_RS06265
uniprot id: Q56NG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BptA family.
messages: Cell outer membrane
messages: Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the spirochete.

521010:BBIDN127 RS04180
gene id: 521010:BBIDN127_RS04180
uniprot id: G0AMS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

521010:BBIDN127 RS01935
gene id: 521010:BBIDN127_RS01935
uniprot id: G0ALJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

521010:BBIDN127 RS04100
gene id: 521010:BBIDN127_RS04100
uniprot id: G0AMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

521010:BBIDN127 RS02705
gene id: 521010:BBIDN127_RS02705
uniprot id: G0ALY9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

521010:BBIDN127 RS01995
gene id: 521010:BBIDN127_RS01995
uniprot id: G0ALK8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

521010:BBIDN127 RS02220
gene id: 521010:BBIDN127_RS02220
uniprot id: G0ALP8
names: Similarity
messages: Belongs to the sigma-54 factor family.

521010:BBIDN127 RS01895
gene id: 521010:BBIDN127_RS01895
uniprot id: G0ALJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521010:BBIDN127 RS01125
gene id: 521010:BBIDN127_RS01125
uniprot id: G0AL38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00705
gene id: 521010:BBIDN127_RS00705
uniprot id: G0AKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521010:BBIDN127 RS04030
gene id: 521010:BBIDN127_RS04030
uniprot id: G0AMP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

521010:BBIDN127 RS03550
gene id: 521010:BBIDN127_RS03550
uniprot id: G0AME8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

521010:BBIDN127 RS00985
gene id: 521010:BBIDN127_RS00985
uniprot id: G0AL13
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

521010:BBIDN127 RS00475
gene id: 521010:BBIDN127_RS00475
uniprot id: G0AKR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

521010:BBIDN127 RS00850
gene id: 521010:BBIDN127_RS00850
uniprot id: G0AKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

521010:BBIDN127 RS02010
gene id: 521010:BBIDN127_RS02010
uniprot id: G0ALL1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

521010:BBIDN127 RS01365
gene id: 521010:BBIDN127_RS01365
uniprot id: G0AL85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

521010:BBIDN127 RS03505
gene id: 521010:BBIDN127_RS03505
uniprot id: G0AME1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

521010:BBIDN127 RS00125
gene id: 521010:BBIDN127_RS00125
uniprot id: G0AKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

521010:BBIDN127 RS01465
gene id: 521010:BBIDN127_RS01465
uniprot id: G0ALA5
names: Similarity
messages: Belongs to the DprA/Smf family.

521010:BBIDN127 RS03945
gene id: 521010:BBIDN127_RS03945
uniprot id: G0AMM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

521010:BBIDN127 RS03980
gene id: 521010:BBIDN127_RS03980
uniprot id: G0AMN1
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01915
gene id: 521010:BBIDN127_RS01915
uniprot id: G0ALJ5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

521010:BBIDN127 RS01105
gene id: 521010:BBIDN127_RS01105
uniprot id: G0AL34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

521010:BBIDN127 RS02960
gene id: 521010:BBIDN127_RS02960
uniprot id: G0AM40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00520
gene id: 521010:BBIDN127_RS00520
uniprot id: G0AKR9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

521010:BBIDN127 RS01085
gene id: 521010:BBIDN127_RS01085
uniprot id: G0AL30
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

521010:BBIDN127 RS05985
gene id: 521010:BBIDN127_RS05985
uniprot id: G0ANV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS02375
gene id: 521010:BBIDN127_RS02375
uniprot id: G0ALS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

521010:BBIDN127 RS03555
gene id: 521010:BBIDN127_RS03555
uniprot id: G0AME9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

521010:BBIDN127 RS05535
gene id: 521010:BBIDN127_RS05535
uniprot id: G0ANK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS02370
gene id: 521010:BBIDN127_RS02370
uniprot id: G0ALS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

521010:BBIDN127 RS01245
gene id: 521010:BBIDN127_RS01245
uniprot id: G0AL60
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

521010:BBIDN127 RS02415
gene id: 521010:BBIDN127_RS02415
uniprot id: G0ALT3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

521010:BBIDN127 RS01880
gene id: 521010:BBIDN127_RS01880
uniprot id: G0ALI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

521010:BBIDN127 RS03520
gene id: 521010:BBIDN127_RS03520
uniprot id: G0AME4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

521010:BBIDN127 RS00270
gene id: 521010:BBIDN127_RS00270
uniprot id: G0AKL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

521010:BBIDN127 RS01790
gene id: 521010:BBIDN127_RS01790
uniprot id: G0ALH1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

521010:BBIDN127 RS00265
gene id: 521010:BBIDN127_RS00265
uniprot id: G0AKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

521010:BBIDN127 RS01965
gene id: 521010:BBIDN127_RS01965
uniprot id: G0ALK2
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01835
gene id: 521010:BBIDN127_RS01835
uniprot id: G0ALI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

521010:BBIDN127 RS02400
gene id: 521010:BBIDN127_RS02400
uniprot id: G0ALT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

521010:BBIDN127 RS00860
gene id: 521010:BBIDN127_RS00860
uniprot id: G0AKY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS01420
gene id: 521010:BBIDN127_RS01420
uniprot id: G0AL96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm

521010:BBIDN127 RS05595
gene id: 521010:BBIDN127_RS05595
uniprot id: G0ANL4
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00590
gene id: 521010:BBIDN127_RS00590
uniprot id: G0AKT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

521010:BBIDN127 RS03175
gene id: 521010:BBIDN127_RS03175
uniprot id: G0AM76
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

521010:BBIDN127 RS01780
gene id: 521010:BBIDN127_RS01780
uniprot id: G0ALG9
names: Similarity
messages: Belongs to the peptidase M18 family.

521010:BBIDN127 RS01450
gene id: 521010:BBIDN127_RS01450
uniprot id: G0ALA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

521010:BBIDN127 RS00325
gene id: 521010:BBIDN127_RS00325
uniprot id: G0AKM9
names: Similarity
messages: Belongs to the peptidase M24B family.

521010:BBIDN127 RS03290
gene id: 521010:BBIDN127_RS03290
uniprot id: G0AM99
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

521010:BBIDN127 RS01760
gene id: 521010:BBIDN127_RS01760
uniprot id: G0ALG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

521010:BBIDN127 RS00960
gene id: 521010:BBIDN127_RS00960
uniprot id: G0AL09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

521010:BBIDN127 RS02170
gene id: 521010:BBIDN127_RS02170
uniprot id: G0ALN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

521010:BBIDN127 RS03415
gene id: 521010:BBIDN127_RS03415
uniprot id: G0AMC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

521010:BBIDN127 RS03975
gene id: 521010:BBIDN127_RS03975
uniprot id: G0AMN0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

521010:BBIDN127 RS04210
gene id: 521010:BBIDN127_RS04210
uniprot id: G0AMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

521010:BBIDN127 RS00540
gene id: 521010:BBIDN127_RS00540
uniprot id: G0AKS3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

521010:BBIDN127 RS03200
gene id: 521010:BBIDN127_RS03200
uniprot id: G0AM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521010:BBIDN127 RS00335
gene id: 521010:BBIDN127_RS00335
uniprot id: G0AKN1
names: Similarity
messages: Belongs to the peptidase M29 family.

521010:BBIDN127 RS01805
gene id: 521010:BBIDN127_RS01805
uniprot id: G0ALH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS03075
gene id: 521010:BBIDN127_RS03075
uniprot id: G0AM59
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

521010:BBIDN127 RS04185
gene id: 521010:BBIDN127_RS04185
uniprot id: G0AMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

521010:BBIDN127 RS00585
gene id: 521010:BBIDN127_RS00585
uniprot id: G0AKT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02845
gene id: 521010:BBIDN127_RS02845
uniprot id: G0AM16
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02380
gene id: 521010:BBIDN127_RS02380
uniprot id: G0ALS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

521010:BBIDN127 RS02715
gene id: 521010:BBIDN127_RS02715
uniprot id: G0ALZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

521010:BBIDN127 RS04220
gene id: 521010:BBIDN127_RS04220
uniprot id: G0AMT0
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00060
gene id: 521010:BBIDN127_RS00060
uniprot id: G0AKH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02110
gene id: 521010:BBIDN127_RS02110
uniprot id: G0ALM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

521010:BBIDN127 RS03455
gene id: 521010:BBIDN127_RS03455
uniprot id: G0AMD1
names: Similarity
messages: Belongs to the Dps family.

521010:BBIDN127 RS02420
gene id: 521010:BBIDN127_RS02420
uniprot id: G0ALT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

521010:BBIDN127 RS02445
gene id: 521010:BBIDN127_RS02445
uniprot id: G0ALT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

521010:BBIDN127 RS03595
gene id: 521010:BBIDN127_RS03595
uniprot id: G0AMF6
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01050
gene id: 521010:BBIDN127_RS01050
uniprot id: G0AL23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

521010:BBIDN127 RS00685
gene id: 521010:BBIDN127_RS00685
uniprot id: G0AKV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

521010:BBIDN127 RS02900
gene id: 521010:BBIDN127_RS02900
uniprot id: G0AM28
names: Similarity
messages: Belongs to the FemABX family.

521010:BBIDN127 RS03620
gene id: 521010:BBIDN127_RS03620
uniprot id: G0AMG1
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02460
gene id: 521010:BBIDN127_RS02460
uniprot id: G0ALU2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

521010:BBIDN127 RS01030
gene id: 521010:BBIDN127_RS01030
uniprot id: G0AL20
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

521010:BBIDN127 RS02430
gene id: 521010:BBIDN127_RS02430
uniprot id: G0ALT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

521010:BBIDN127 RS00370
gene id: 521010:BBIDN127_RS00370
uniprot id: G0AKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521010:BBIDN127 RS02435
gene id: 521010:BBIDN127_RS02435
uniprot id: G0ALT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

521010:BBIDN127 RS03940
gene id: 521010:BBIDN127_RS03940
uniprot id: G0AMM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

521010:BBIDN127 RS02495
gene id: 521010:BBIDN127_RS02495
uniprot id: G0ALU9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

521010:BBIDN127 RS00660
gene id: 521010:BBIDN127_RS00660
uniprot id: G0AKU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS03485
gene id: 521010:BBIDN127_RS03485
uniprot id: G0AMD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

521010:BBIDN127 RS03005
gene id: 521010:BBIDN127_RS03005
uniprot id: G0AM49
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521010:BBIDN127 RS03065
gene id: 521010:BBIDN127_RS03065
uniprot id: G0AM57
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02575
gene id: 521010:BBIDN127_RS02575
uniprot id: G0ALW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

521010:BBIDN127 RS02990
gene id: 521010:BBIDN127_RS02990
uniprot id: G0AM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

521010:BBIDN127 RS00895
gene id: 521010:BBIDN127_RS00895
uniprot id: G0AKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

521010:BBIDN127 RS03145
gene id: 521010:BBIDN127_RS03145
uniprot id: G0AM71
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

521010:BBIDN127 RS05725
gene id: 521010:BBIDN127_RS05725
uniprot id: G0ANP0
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS03235
gene id: 521010:BBIDN127_RS03235
uniprot id: G0AM88
names: Similarity
messages: Belongs to the Fur family.

521010:BBIDN127 RS02995
gene id: 521010:BBIDN127_RS02995
uniprot id: G0AM47
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

521010:BBIDN127 RS04330
gene id: 521010:BBIDN127_RS04330
uniprot id: G0AMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS01300
gene id: 521010:BBIDN127_RS01300
uniprot id: G0AL72
names: Similarity
messages: Belongs to the heat shock protein 70 family.

521010:BBIDN127 RS03395
gene id: 521010:BBIDN127_RS03395
uniprot id: G0AMC0
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00075
gene id: 521010:BBIDN127_RS00075
uniprot id: G0AKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

521010:BBIDN127 RS01710
gene id: 521010:BBIDN127_RS01710
uniprot id: G0ALF5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

521010:BBIDN127 RS02325
gene id: 521010:BBIDN127_RS02325
uniprot id: G0ALR5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

521010:BBIDN127 RS01680
gene id: 521010:BBIDN127_RS01680
uniprot id: G0ALE9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521010:BBIDN127 RS03185
gene id: 521010:BBIDN127_RS03185
uniprot id: G0AM78
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01510
gene id: 521010:BBIDN127_RS01510
uniprot id: G0ALB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

521010:BBIDN127 RS02545
gene id: 521010:BBIDN127_RS02545
uniprot id: G0ALV9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

521010:BBIDN127 RS01260
gene id: 521010:BBIDN127_RS01260
uniprot id: G0AL63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

521010:BBIDN127 RS03880
gene id: 521010:BBIDN127_RS03880
uniprot id: G0AML2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

521010:BBIDN127 RS03895
gene id: 521010:BBIDN127_RS03895
uniprot id: G0AML5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

521010:BBIDN127 RS04050
gene id: 521010:BBIDN127_RS04050
uniprot id: G0AMP5
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01655
gene id: 521010:BBIDN127_RS01655
uniprot id: G0ALE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

521010:BBIDN127 RS00965
gene id: 521010:BBIDN127_RS00965
uniprot id: G0AL10
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS01350
gene id: 521010:BBIDN127_RS01350
uniprot id: G0AL82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

521010:BBIDN127 RS00725
gene id: 521010:BBIDN127_RS00725
uniprot id: G0AKW1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

521010:BBIDN127 RS06755
gene id: 521010:BBIDN127_RS06755
uniprot id: G0APD9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS02765
gene id: 521010:BBIDN127_RS02765
uniprot id: G0AM01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

521010:BBIDN127 RS03740
gene id: 521010:BBIDN127_RS03740
uniprot id: G0AMI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521010:BBIDN127 RS03910
gene id: 521010:BBIDN127_RS03910
uniprot id: G0AML8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

521010:BBIDN127 RS03830
gene id: 521010:BBIDN127_RS03830
uniprot id: G0AMK2
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02230
gene id: 521010:BBIDN127_RS02230
uniprot id: G0ALQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

521010:BBIDN127 RS03035
gene id: 521010:BBIDN127_RS03035
uniprot id: G0AM51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

521010:BBIDN127 RS02335
gene id: 521010:BBIDN127_RS02335
uniprot id: G0ALR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

521010:BBIDN127 RS01340
gene id: 521010:BBIDN127_RS01340
uniprot id: G0AL80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

521010:BBIDN127 RS01220
gene id: 521010:BBIDN127_RS01220
uniprot id: G0AL56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

521010:BBIDN127 RS03190
gene id: 521010:BBIDN127_RS03190
uniprot id: G0AM79
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02475
gene id: 521010:BBIDN127_RS02475
uniprot id: G0ALU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

521010:BBIDN127 RS04010
gene id: 521010:BBIDN127_RS04010
uniprot id: G0AMN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

521010:BBIDN127 RS03955
gene id: 521010:BBIDN127_RS03955
uniprot id: G0AMM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

521010:BBIDN127 RS03295
gene id: 521010:BBIDN127_RS03295
uniprot id: G0AMA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00565
gene id: 521010:BBIDN127_RS00565
uniprot id: G0AKS8
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00550
gene id: 521010:BBIDN127_RS00550
uniprot id: G0AKS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

521010:BBIDN127 RS03855
gene id: 521010:BBIDN127_RS03855
uniprot id: G0AMK7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521010:BBIDN127 RS03525
gene id: 521010:BBIDN127_RS03525
uniprot id: G0AME5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

521010:BBIDN127 RS00165
gene id: 521010:BBIDN127_RS00165
uniprot id: G0AKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

521010:BBIDN127 RS02450
gene id: 521010:BBIDN127_RS02450
uniprot id: G0ALU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

521010:BBIDN127 RS01135
gene id: 521010:BBIDN127_RS01135
uniprot id: G0AL40
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

521010:BBIDN127 RS00510
gene id: 521010:BBIDN127_RS00510
uniprot id: G0AKR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

521010:BBIDN127 RS04710
gene id: 521010:BBIDN127_RS04710
uniprot id: G0AN32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS04230
gene id: 521010:BBIDN127_RS04230
uniprot id: G0AMT1
names: Similarity
messages: Belongs to the acylphosphatase family.

521010:BBIDN127 RS02875
gene id: 521010:BBIDN127_RS02875
uniprot id: G0AM22
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

521010:BBIDN127 RS00555
gene id: 521010:BBIDN127_RS00555
uniprot id: G0AKS6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS03865
gene id: 521010:BBIDN127_RS03865
uniprot id: G0AMK9
names: Function
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body

521010:BBIDN127 RS04500
gene id: 521010:BBIDN127_RS04500
uniprot id: G0AMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS01540
gene id: 521010:BBIDN127_RS01540
uniprot id: G0ALC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

521010:BBIDN127 RS02625
gene id: 521010:BBIDN127_RS02625
uniprot id: G0ALX5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

521010:BBIDN127 RS01920
gene id: 521010:BBIDN127_RS01920
uniprot id: G0ALJ6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

521010:BBIDN127 RS02940
gene id: 521010:BBIDN127_RS02940
uniprot id: G0AM36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

521010:BBIDN127 RS02635
gene id: 521010:BBIDN127_RS02635
uniprot id: G0ALX7
names: Similarity
messages: Belongs to the peptidase M16 family.

521010:BBIDN127 RS01800
gene id: 521010:BBIDN127_RS01800
uniprot id: G0ALH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS00110
gene id: 521010:BBIDN127_RS00110
uniprot id: G0AKI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

521010:BBIDN127 RS01150
gene id: 521010:BBIDN127_RS01150
uniprot id: G0AL43
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

521010:BBIDN127 RS01650
gene id: 521010:BBIDN127_RS01650
uniprot id: G0ALE3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

521010:BBIDN127 RS02525
gene id: 521010:BBIDN127_RS02525
uniprot id: G0ALV5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

521010:BBIDN127 RS02295
gene id: 521010:BBIDN127_RS02295
uniprot id: G0ALQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

521010:BBIDN127 RS03685
gene id: 521010:BBIDN127_RS03685
uniprot id: G0AMH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

521010:BBIDN127 RS00575
gene id: 521010:BBIDN127_RS00575
uniprot id: G0AKT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

521010:BBIDN127 RS02470
gene id: 521010:BBIDN127_RS02470
uniprot id: G0ALU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521010:BBIDN127 RS00300
gene id: 521010:BBIDN127_RS00300
uniprot id: G0AKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

521010:BBIDN127 RS02920
gene id: 521010:BBIDN127_RS02920
uniprot id: G0AM32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

521010:BBIDN127 RS00100
gene id: 521010:BBIDN127_RS00100
uniprot id: G0AKI4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

521010:BBIDN127 RS00880
gene id: 521010:BBIDN127_RS00880
uniprot id: G0AKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

521010:BBIDN127 RS00875
gene id: 521010:BBIDN127_RS00875
uniprot id: G0AKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

521010:BBIDN127 RS01905
gene id: 521010:BBIDN127_RS01905
uniprot id: G0ALJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

521010:BBIDN127 RS00885
gene id: 521010:BBIDN127_RS00885
uniprot id: G0AKZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

521010:BBIDN127 RS03480
gene id: 521010:BBIDN127_RS03480
uniprot id: G0AMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

521010:BBIDN127 RS04145
gene id: 521010:BBIDN127_RS04145
uniprot id: G0AMR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

521010:BBIDN127 RS03600
gene id: 521010:BBIDN127_RS03600
uniprot id: G0AMF7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02405
gene id: 521010:BBIDN127_RS02405
uniprot id: G0ALT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

521010:BBIDN127 RS03765
gene id: 521010:BBIDN127_RS03765
uniprot id: G0AMI9
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02500
gene id: 521010:BBIDN127_RS02500
uniprot id: G0ALV0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

521010:BBIDN127 RS03340
gene id: 521010:BBIDN127_RS03340
uniprot id: G0AMA9
names: Function
names: Subcellular Location Annotation
messages: Component of the outer layer of the flagella.
messages: Periplasmic flagellum

521010:BBIDN127 RS02550
gene id: 521010:BBIDN127_RS02550
uniprot id: G0ALW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521010:BBIDN127 RS01910
gene id: 521010:BBIDN127_RS01910
uniprot id: G0ALJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

521010:BBIDN127 RS01490
gene id: 521010:BBIDN127_RS01490
uniprot id: G0ALB0
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS01080
gene id: 521010:BBIDN127_RS01080
uniprot id: G0AL29
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

521010:BBIDN127 RS03700
gene id: 521010:BBIDN127_RS03700
uniprot id: G0AMH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

521010:BBIDN127 RS03470
gene id: 521010:BBIDN127_RS03470
uniprot id: G0AMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

521010:BBIDN127 RS00405
gene id: 521010:BBIDN127_RS00405
uniprot id: G0AKP6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

521010:BBIDN127 RS04140
gene id: 521010:BBIDN127_RS04140
uniprot id: G0AMR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

521010:BBIDN127 RS00560
gene id: 521010:BBIDN127_RS00560
uniprot id: G0AKS7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

521010:BBIDN127 RS03180
gene id: 521010:BBIDN127_RS03180
uniprot id: G0AM77
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00915
gene id: 521010:BBIDN127_RS00915
uniprot id: G0AL00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

521010:BBIDN127 RS04015
gene id: 521010:BBIDN127_RS04015
uniprot id: G0AMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

521010:BBIDN127 RS03210
gene id: 521010:BBIDN127_RS03210
uniprot id: G0AM83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

521010:BBIDN127 RS02490
gene id: 521010:BBIDN127_RS02490
uniprot id: G0ALU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

521010:BBIDN127 RS01545
gene id: 521010:BBIDN127_RS01545
uniprot id: G0ALC1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

521010:BBIDN127 RS03650
gene id: 521010:BBIDN127_RS03650
uniprot id: G0AMG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

521010:BBIDN127 RS00015
gene id: 521010:BBIDN127_RS00015
uniprot id: G0AKG7
names: Similarity
messages: Belongs to the UDPGP type 1 family.

521010:BBIDN127 RS01670
gene id: 521010:BBIDN127_RS01670
uniprot id: G0ALE7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

521010:BBIDN127 RS01060
gene id: 521010:BBIDN127_RS01060
uniprot id: G0AL25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

521010:BBIDN127 RS03905
gene id: 521010:BBIDN127_RS03905
uniprot id: G0AML7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

521010:BBIDN127 RS01210
gene id: 521010:BBIDN127_RS01210
uniprot id: G0AL54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

521010:BBIDN127 RS03675
gene id: 521010:BBIDN127_RS03675
uniprot id: G0AMH2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

521010:BBIDN127 RS02455
gene id: 521010:BBIDN127_RS02455
uniprot id: G0ALU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

521010:BBIDN127 RS04325
gene id: 521010:BBIDN127_RS04325
uniprot id: G0AMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS00145
gene id: 521010:BBIDN127_RS00145
uniprot id: G0AKJ3
names: Similarity
messages: Belongs to the UPF0178 family.

521010:BBIDN127 RS01970
gene id: 521010:BBIDN127_RS01970
uniprot id: G0ALK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS07000
gene id: 521010:BBIDN127_RS07000
uniprot id: G0APJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS04055
gene id: 521010:BBIDN127_RS04055
uniprot id: G0AMP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

521010:BBIDN127 RS00735
gene id: 521010:BBIDN127_RS00735
uniprot id: G0AKW3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

521010:BBIDN127 RS02155
gene id: 521010:BBIDN127_RS02155
uniprot id: G0ALN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

521010:BBIDN127 RS02385
gene id: 521010:BBIDN127_RS02385
uniprot id: G0ALS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

521010:BBIDN127 RS04110
gene id: 521010:BBIDN127_RS04110
uniprot id: G0AMQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521010:BBIDN127 RS00415
gene id: 521010:BBIDN127_RS00415
uniprot id: G0AKP8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

521010:BBIDN127 RS00230
gene id: 521010:BBIDN127_RS00230
uniprot id: G0AKL0
names: Subcellular Location Annotation
messages: Nucleus

521010:BBIDN127 RS01885
gene id: 521010:BBIDN127_RS01885
uniprot id: G0ALI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

521010:BBIDN127 RS01120
gene id: 521010:BBIDN127_RS01120
uniprot id: G0AL37
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

521010:BBIDN127 RS00040
gene id: 521010:BBIDN127_RS00040
uniprot id: G0AKH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

521010:BBIDN127 RS00490
gene id: 521010:BBIDN127_RS00490
uniprot id: G0AKR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS03635
gene id: 521010:BBIDN127_RS03635
uniprot id: G0AMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS04075
gene id: 521010:BBIDN127_RS04075
uniprot id: G0AMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

521010:BBIDN127 RS02725
gene id: 521010:BBIDN127_RS02725
uniprot id: G0ALZ3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

521010:BBIDN127 RS00480
gene id: 521010:BBIDN127_RS00480
uniprot id: G0AKR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

521010:BBIDN127 RS00155
gene id: 521010:BBIDN127_RS00155
uniprot id: G0AKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

521010:BBIDN127 RS00445
gene id: 521010:BBIDN127_RS00445
uniprot id: G0AKQ4
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

521010:BBIDN127 RS02225
gene id: 521010:BBIDN127_RS02225
uniprot id: G0ALP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

521010:BBIDN127 RS04215
gene id: 521010:BBIDN127_RS04215
uniprot id: G0AMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

521010:BBIDN127 RS02665
gene id: 521010:BBIDN127_RS02665
uniprot id: G0ALY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

521010:BBIDN127 RS04090
gene id: 521010:BBIDN127_RS04090
uniprot id: G0AMQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

521010:BBIDN127 RS00870
gene id: 521010:BBIDN127_RS00870
uniprot id: G0AKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

521010:BBIDN127 RS03515
gene id: 521010:BBIDN127_RS03515
uniprot id: G0AME3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

521010:BBIDN127 RS02485
gene id: 521010:BBIDN127_RS02485
uniprot id: G0ALU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

521010:BBIDN127 RS03225
gene id: 521010:BBIDN127_RS03225
uniprot id: G0AM86
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02160
gene id: 521010:BBIDN127_RS02160
uniprot id: G0ALN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

521010:BBIDN127 RS00645
gene id: 521010:BBIDN127_RS00645
uniprot id: G0AKU4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

521010:BBIDN127 RS02565
gene id: 521010:BBIDN127_RS02565
uniprot id: G0ALW3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

521010:BBIDN127 RS00025
gene id: 521010:BBIDN127_RS00025
uniprot id: G0AKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS00715
gene id: 521010:BBIDN127_RS00715
uniprot id: G0AKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

521010:BBIDN127 RS06135
gene id: 521010:BBIDN127_RS06135
uniprot id: G0ANY2
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00740
gene id: 521010:BBIDN127_RS00740
uniprot id: G0AKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

521010:BBIDN127 RS03495
gene id: 521010:BBIDN127_RS03495
uniprot id: G0AMD9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

521010:BBIDN127 RS00945
gene id: 521010:BBIDN127_RS00945
uniprot id: G0AL06
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

521010:BBIDN127 RS03420
gene id: 521010:BBIDN127_RS03420
uniprot id: G0AMC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02145
gene id: 521010:BBIDN127_RS02145
uniprot id: G0ALN3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

521010:BBIDN127 RS00030
gene id: 521010:BBIDN127_RS00030
uniprot id: G0AKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

521010:BBIDN127 RS01385
gene id: 521010:BBIDN127_RS01385
uniprot id: G0AL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

521010:BBIDN127 RS03775
gene id: 521010:BBIDN127_RS03775
uniprot id: G0AMJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

521010:BBIDN127 RS03425
gene id: 521010:BBIDN127_RS03425
uniprot id: G0AMC6
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

521010:BBIDN127 RS01850
gene id: 521010:BBIDN127_RS01850
uniprot id: G0ALI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521010:BBIDN127 RS01455
gene id: 521010:BBIDN127_RS01455
uniprot id: G0ALA3
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

521010:BBIDN127 RS00795
gene id: 521010:BBIDN127_RS00795
uniprot id: G0AKX6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

521010:BBIDN127 RS00205
gene id: 521010:BBIDN127_RS00205
uniprot id: G0AKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

521010:BBIDN127 RS03835
gene id: 521010:BBIDN127_RS03835
uniprot id: G0AMK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02915
gene id: 521010:BBIDN127_RS02915
uniprot id: G0AM31
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

521010:BBIDN127 RS02905
gene id: 521010:BBIDN127_RS02905
uniprot id: G0AM29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

521010:BBIDN127 RS04915
gene id: 521010:BBIDN127_RS04915
uniprot id: G0AN73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS00810
gene id: 521010:BBIDN127_RS00810
uniprot id: G0AKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

521010:BBIDN127 RS03670
gene id: 521010:BBIDN127_RS03670
uniprot id: G0AMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

521010:BBIDN127 RS03430
gene id: 521010:BBIDN127_RS03430
uniprot id: G0AMC7
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

521010:BBIDN127 RS00905
gene id: 521010:BBIDN127_RS00905
uniprot id: G0AKZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

521010:BBIDN127 RS01010
gene id: 521010:BBIDN127_RS01010
uniprot id: G0AL16
names: Similarity
messages: Belongs to the UDPGP type 2 family.

521010:BBIDN127 RS00545
gene id: 521010:BBIDN127_RS00545
uniprot id: G0AKS4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

521010:BBIDN127 RS03410
gene id: 521010:BBIDN127_RS03410
uniprot id: G0AMC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00455
gene id: 521010:BBIDN127_RS00455
uniprot id: G0AKQ6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

521010:BBIDN127 RS00105
gene id: 521010:BBIDN127_RS00105
uniprot id: G0AKI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

521010:BBIDN127 RS00115
gene id: 521010:BBIDN127_RS00115
uniprot id: G0AKI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

521010:BBIDN127 RS04175
gene id: 521010:BBIDN127_RS04175
uniprot id: G0AMS1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521010:BBIDN127 RS01770
gene id: 521010:BBIDN127_RS01770
uniprot id: G0ALG7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

521010:BBIDN127 RS02365
gene id: 521010:BBIDN127_RS02365
uniprot id: G0ALS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

521010:BBIDN127 RS02440
gene id: 521010:BBIDN127_RS02440
uniprot id: G0ALT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

521010:BBIDN127 RS02505
gene id: 521010:BBIDN127_RS02505
uniprot id: G0ALV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

521010:BBIDN127 RS03130
gene id: 521010:BBIDN127_RS03130
uniprot id: G0AM68
names: Similarity
messages: Belongs to the peptidase M18 family.

521010:BBIDN127 RS02410
gene id: 521010:BBIDN127_RS02410
uniprot id: G0ALT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

521010:BBIDN127 RS02255
gene id: 521010:BBIDN127_RS02255
uniprot id: G0ALQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

521010:BBIDN127 RS04005
gene id: 521010:BBIDN127_RS04005
uniprot id: G0AMN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

521010:BBIDN127 RS03045
gene id: 521010:BBIDN127_RS03045
uniprot id: G0AM53
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521010:BBIDN127 RS03475
gene id: 521010:BBIDN127_RS03475
uniprot id: G0AMD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

521010:BBIDN127 RS01625
gene id: 521010:BBIDN127_RS01625
uniprot id: G0ALD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS01270
gene id: 521010:BBIDN127_RS01270
uniprot id: G0AL65
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

521010:BBIDN127 RS02580
gene id: 521010:BBIDN127_RS02580
uniprot id: G0ALW6
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

521010:BBIDN127 RS00910
gene id: 521010:BBIDN127_RS00910
uniprot id: G0AKZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

521010:BBIDN127 RS00980
gene id: 521010:BBIDN127_RS00980
uniprot id: G0AL12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

521010:BBIDN127 RS00855
gene id: 521010:BBIDN127_RS00855
uniprot id: G0AKY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

521010:BBIDN127 RS03140
gene id: 521010:BBIDN127_RS03140
uniprot id: G0AM70
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

521010:BBIDN127 RS03845
gene id: 521010:BBIDN127_RS03845
uniprot id: G0AMK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

521010:BBIDN127 RS00630
gene id: 521010:BBIDN127_RS00630
uniprot id: G0AKU1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

521010:BBIDN127 RS00130
gene id: 521010:BBIDN127_RS00130
uniprot id: G0AKJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

521010:BBIDN127 RS01330
gene id: 521010:BBIDN127_RS01330
uniprot id: G0AL78
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

521010:BBIDN127 RS01700
gene id: 521010:BBIDN127_RS01700
uniprot id: G0ALF3
names: Similarity
messages: Belongs to the pyruvate kinase family.

521010:BBIDN127 RS01530
gene id: 521010:BBIDN127_RS01530
uniprot id: G0ALB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS00940
gene id: 521010:BBIDN127_RS00940
uniprot id: G0AL05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

521010:BBIDN127 RS03605
gene id: 521010:BBIDN127_RS03605
uniprot id: G0AMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

521010:BBIDN127 RS01810
gene id: 521010:BBIDN127_RS01810
uniprot id: G0ALH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521010:BBIDN127 RS02685
gene id: 521010:BBIDN127_RS02685
uniprot id: G0ALY5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

521010:BBIDN127 RS03950
gene id: 521010:BBIDN127_RS03950
uniprot id: G0AMM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

521010:BBIDN127 RS05860
gene id: 521010:BBIDN127_RS05860
uniprot id: G0ANS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS02150
gene id: 521010:BBIDN127_RS02150
uniprot id: G0ALN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

521010:BBIDN127 RS02750
gene id: 521010:BBIDN127_RS02750
uniprot id: G0ALZ8
names: Subcellular Location Annotation
messages: Cytoplasm

521010:BBIDN127 RS03260
gene id: 521010:BBIDN127_RS03260
uniprot id: G0AM93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

521010:BBIDN127 RS00090
gene id: 521010:BBIDN127_RS00090
uniprot id: G0AKI2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

521010:BBIDN127 RS00435
gene id: 521010:BBIDN127_RS00435
uniprot id: G0AKQ2
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00440
gene id: 521010:BBIDN127_RS00440
uniprot id: G0AKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

521010:BBIDN127 RS05660
gene id: 521010:BBIDN127_RS05660
uniprot id: G0ANM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS00450
gene id: 521010:BBIDN127_RS00450
uniprot id: G0AKQ5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

521010:BBIDN127 RS01430
gene id: 521010:BBIDN127_RS01430
uniprot id: G0AL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

521010:BBIDN127 RS01475
gene id: 521010:BBIDN127_RS01475
uniprot id: G0ALA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

521010:BBIDN127 RS00315
gene id: 521010:BBIDN127_RS00315
uniprot id: G0AKM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

521010:BBIDN127 RS01870
gene id: 521010:BBIDN127_RS01870
uniprot id: G0ALI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMP lipoprotein family.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS01375
gene id: 521010:BBIDN127_RS01375
uniprot id: G0AL87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

521010:BBIDN127 RS01860
gene id: 521010:BBIDN127_RS01860
uniprot id: G0ALI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMP lipoprotein family.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS00730
gene id: 521010:BBIDN127_RS00730
uniprot id: G0AKW2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS03890
gene id: 521010:BBIDN127_RS03890
uniprot id: G0AML4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

521010:BBIDN127 RS00390
gene id: 521010:BBIDN127_RS00390
uniprot id: G0AKP3
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS04020
gene id: 521010:BBIDN127_RS04020
uniprot id: G0AMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

521010:BBIDN127 RS02555
gene id: 521010:BBIDN127_RS02555
uniprot id: G0ALW1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

521010:BBIDN127 RS01570
gene id: 521010:BBIDN127_RS01570
uniprot id: G0ALC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMP lipoprotein family.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS01235
gene id: 521010:BBIDN127_RS01235
uniprot id: G0AL58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521010:BBIDN127 RS02235
gene id: 521010:BBIDN127_RS02235
uniprot id: G0ALQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

521010:BBIDN127 RS03640
gene id: 521010:BBIDN127_RS03640
uniprot id: G0AMG5
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

521010:BBIDN127 RS06750
gene id: 521010:BBIDN127_RS06750
uniprot id: G0APD8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS03995
gene id: 521010:BBIDN127_RS03995
uniprot id: G0AMN4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

521010:BBIDN127 RS01355
gene id: 521010:BBIDN127_RS01355
uniprot id: G0AL83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

521010:BBIDN127 RS02660
gene id: 521010:BBIDN127_RS02660
uniprot id: G0ALY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

521010:BBIDN127 RS00020
gene id: 521010:BBIDN127_RS00020
uniprot id: G0AKG8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521010:BBIDN127 RS00085
gene id: 521010:BBIDN127_RS00085
uniprot id: G0AKI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS00595
gene id: 521010:BBIDN127_RS00595
uniprot id: G0AKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

521010:BBIDN127 RS01140
gene id: 521010:BBIDN127_RS01140
uniprot id: G0AL41
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

521010:BBIDN127 RS02390
gene id: 521010:BBIDN127_RS02390
uniprot id: G0ALS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

521010:BBIDN127 RS01460
gene id: 521010:BBIDN127_RS01460
uniprot id: G0ALA4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

521010:BBIDN127 RS01250
gene id: 521010:BBIDN127_RS01250
uniprot id: G0AL61
names: Similarity
messages: Belongs to the RecJ family.

521010:BBIDN127 RS02865
gene id: 521010:BBIDN127_RS02865
uniprot id: G0AM20
names: Subcellular Location Annotation
messages: Cytoplasm

521010:BBIDN127 RS00290
gene id: 521010:BBIDN127_RS00290
uniprot id: G0AKM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

521010:BBIDN127 RS00570
gene id: 521010:BBIDN127_RS00570
uniprot id: G0AKS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

521010:BBIDN127 RS01500
gene id: 521010:BBIDN127_RS01500
uniprot id: G0ALB2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

521010:BBIDN127 RS01560
gene id: 521010:BBIDN127_RS01560
uniprot id: G0ALC4
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS00185
gene id: 521010:BBIDN127_RS00185
uniprot id: G0AKK1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

521010:BBIDN127 RS01175
gene id: 521010:BBIDN127_RS01175
uniprot id: G0AL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

521010:BBIDN127 RS03785
gene id: 521010:BBIDN127_RS03785
uniprot id: G0AMJ3
names: Similarity
messages: Belongs to the peptidase S14 family.

521010:BBIDN127 RS01400
gene id: 521010:BBIDN127_RS01400
uniprot id: G0AL92
names: Similarity
messages: Belongs to the FlgD family.

521010:BBIDN127 RS00050
gene id: 521010:BBIDN127_RS00050
uniprot id: G0AKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

521010:BBIDN127 RS01900
gene id: 521010:BBIDN127_RS01900
uniprot id: G0ALJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

521010:BBIDN127 RS00225
gene id: 521010:BBIDN127_RS00225
uniprot id: G0AKK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

521010:BBIDN127 RS02700
gene id: 521010:BBIDN127_RS02700
uniprot id: G0ALY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

521010:BBIDN127 RS01240
gene id: 521010:BBIDN127_RS01240
uniprot id: G0AL59
names: Subcellular Location Annotation
messages: Membrane

521010:BBIDN127 RS02040
gene id: 521010:BBIDN127_RS02040
uniprot id: G0ALL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

521010:BBIDN127 RS03000
gene id: 521010:BBIDN127_RS03000
uniprot id: G0AM48
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

521010:BBIDN127 RS01090
gene id: 521010:BBIDN127_RS01090
uniprot id: G0AL31
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

521010:BBIDN127 RS01160
gene id: 521010:BBIDN127_RS01160
uniprot id: G0AL45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

521010:BBIDN127 RS03055
gene id: 521010:BBIDN127_RS03055
uniprot id: G0AM56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

521010:BBIDN127 RS02755
gene id: 521010:BBIDN127_RS02755
uniprot id: G0ALZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

521010:BBIDN127 RS01865
gene id: 521010:BBIDN127_RS01865
uniprot id: G0ALI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMP lipoprotein family.
messages: Cell membrane
messages: Membrane

521010:BBIDN127 RS05775
gene id: 521010:BBIDN127_RS05775
uniprot id: G0ANQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Cell outer membrane
messages: Membrane

521010:BBIDN127 RS04060
gene id: 521010:BBIDN127_RS04060
uniprot id: G0AMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

521010:BBIDN127 RS02195
gene id: 521010:BBIDN127_RS02195
uniprot id: G0ALP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.