517418:CTHA RS05365
gene id: 517418:CTHA_RS05365
uniprot id: B3QXW6
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

517418:CTHA RS03475
gene id: 517418:CTHA_RS03475
uniprot id: B3QVT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

517418:CTHA RS06065
gene id: 517418:CTHA_RS06065
uniprot id: B3QYJ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

517418:CTHA RS06470
gene id: 517418:CTHA_RS06470
uniprot id: B3QZ06
names: Similarity
messages: Belongs to the ribF family.

517418:CTHA RS11530
gene id: 517418:CTHA_RS11530
uniprot id: B3QW08
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

517418:CTHA RS09830
gene id: 517418:CTHA_RS09830
uniprot id: B3QU85
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

517418:CTHA RS05965
gene id: 517418:CTHA_RS05965
uniprot id: B3QYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

517418:CTHA RS08070
gene id: 517418:CTHA_RS08070
uniprot id: B3QS57
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

517418:CTHA RS02700
gene id: 517418:CTHA_RS02700
uniprot id: B3QV44
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS00585
gene id: 517418:CTHA_RS00585
uniprot id: B3QSU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

517418:CTHA RS13240
gene id: 517418:CTHA_RS13240
uniprot id: B3QXS6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

517418:CTHA RS12935
gene id: 517418:CTHA_RS12935
uniprot id: B3QXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS09845
gene id: 517418:CTHA_RS09845
uniprot id: B3QU88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS02665
gene id: 517418:CTHA_RS02665
uniprot id: B3QV37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS11715
gene id: 517418:CTHA_RS11715
uniprot id: B3QW47
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS12825
gene id: 517418:CTHA_RS12825
uniprot id: B3QXJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

517418:CTHA RS09745
gene id: 517418:CTHA_RS09745
uniprot id: B3QTX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS12820
gene id: 517418:CTHA_RS12820
uniprot id: B3QXJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

517418:CTHA RS02475
gene id: 517418:CTHA_RS02475
uniprot id: B3QUP7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

517418:CTHA RS03170
gene id: 517418:CTHA_RS03170
uniprot id: B3QVN1
names: Similarity
messages: Belongs to the DprA/Smf family.

517418:CTHA RS11795
gene id: 517418:CTHA_RS11795
uniprot id: B3QWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS11995
gene id: 517418:CTHA_RS11995
uniprot id: B3QWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS01170
gene id: 517418:CTHA_RS01170
uniprot id: B3QTE9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

517418:CTHA RS13580
gene id: 517418:CTHA_RS13580
uniprot id: B3QY92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS05060
gene id: 517418:CTHA_RS05060
uniprot id: B3QXF9
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS10860
gene id: 517418:CTHA_RS10860
uniprot id: B3QVC6
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

517418:CTHA RS09795
gene id: 517418:CTHA_RS09795
uniprot id: B3QTX9
names: Similarity
messages: Belongs to the LOG family.

517418:CTHA RS10265
gene id: 517418:CTHA_RS10265
uniprot id: B3QUG6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

517418:CTHA RS12715
gene id: 517418:CTHA_RS12715
uniprot id: B3QX81
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

517418:CTHA RS10010
gene id: 517418:CTHA_RS10010
uniprot id: B3QUB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

517418:CTHA RS03840
gene id: 517418:CTHA_RS03840
uniprot id: B3QW99
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

517418:CTHA RS14300
gene id: 517418:CTHA_RS14300
uniprot id: B3QU00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

517418:CTHA RS05375
gene id: 517418:CTHA_RS05375
uniprot id: B3QXW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

517418:CTHA RS05480
gene id: 517418:CTHA_RS05480
uniprot id: B3QXY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

517418:CTHA RS13605
gene id: 517418:CTHA_RS13605
uniprot id: B3QY96
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

517418:CTHA RS08975
gene id: 517418:CTHA_RS08975
uniprot id: B3QT72
names: Similarity
messages: Belongs to the peptidase M16 family.

517418:CTHA RS13755
gene id: 517418:CTHA_RS13755
uniprot id: B3QYC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

517418:CTHA RS07940
gene id: 517418:CTHA_RS07940
uniprot id: B3QS33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

517418:CTHA RS12585
gene id: 517418:CTHA_RS12585
uniprot id: B3QX59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS03300
gene id: 517418:CTHA_RS03300
uniprot id: B3QVQ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS08105
gene id: 517418:CTHA_RS08105
uniprot id: B3QS63
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS09685
gene id: 517418:CTHA_RS09685
uniprot id: B3QTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

517418:CTHA RS08755
gene id: 517418:CTHA_RS08755
uniprot id: B3QST3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

517418:CTHA RS07270
gene id: 517418:CTHA_RS07270
uniprot id: B3QRQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS07535
gene id: 517418:CTHA_RS07535
uniprot id: B3QRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

517418:CTHA RS00630
gene id: 517418:CTHA_RS00630
uniprot id: B3QSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

517418:CTHA RS14470
gene id: 517418:CTHA_RS14470
uniprot id: B3QXH1
names: Similarity
messages: Belongs to the peptidase C40 family.

517418:CTHA RS13845
gene id: 517418:CTHA_RS13845
uniprot id: B3QYN6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

517418:CTHA RS07370
gene id: 517418:CTHA_RS07370
uniprot id: B3QRS0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

517418:CTHA RS06430
gene id: 517418:CTHA_RS06430
uniprot id: B3QYZ8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

517418:CTHA RS00965
gene id: 517418:CTHA_RS00965
uniprot id: B3QT14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

517418:CTHA RS06865
gene id: 517418:CTHA_RS06865
uniprot id: B3QZ82
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS09820
gene id: 517418:CTHA_RS09820
uniprot id: B3QU83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

517418:CTHA RS08475
gene id: 517418:CTHA_RS08475
uniprot id: B3QSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

517418:CTHA RS07795
gene id: 517418:CTHA_RS07795
uniprot id: B3QS09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

517418:CTHA RS09565
gene id: 517418:CTHA_RS09565
uniprot id: B3QTT4
names: Similarity
messages: Belongs to the HupF/HypC family.

517418:CTHA RS02510
gene id: 517418:CTHA_RS02510
uniprot id: B3QUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

517418:CTHA RS04095
gene id: 517418:CTHA_RS04095
uniprot id: B3QWD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS11800
gene id: 517418:CTHA_RS11800
uniprot id: B3QWF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

517418:CTHA RS05180
gene id: 517418:CTHA_RS05180
uniprot id: B3QXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS03250
gene id: 517418:CTHA_RS03250
uniprot id: B3QVP5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

517418:CTHA RS13275
gene id: 517418:CTHA_RS13275
uniprot id: B3QY32
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

517418:CTHA RS06340
gene id: 517418:CTHA_RS06340
uniprot id: B3QYY1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS00820
gene id: 517418:CTHA_RS00820
uniprot id: B3QSY6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

517418:CTHA RS04485
gene id: 517418:CTHA_RS04485
uniprot id: B3QWW3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

517418:CTHA RS12670
gene id: 517418:CTHA_RS12670
uniprot id: B3QX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

517418:CTHA RS02985
gene id: 517418:CTHA_RS02985
uniprot id: B3QVA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS01595
gene id: 517418:CTHA_RS01595
uniprot id: B3QTY3
names: Similarity
messages: Belongs to the DEAD box helicase family.

517418:CTHA RS05685
gene id: 517418:CTHA_RS05685
uniprot id: B3QY26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

517418:CTHA RS05825
gene id: 517418:CTHA_RS05825
uniprot id: B3QYF4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

517418:CTHA RS12605
gene id: 517418:CTHA_RS12605
uniprot id: B3QX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

517418:CTHA RS12485
gene id: 517418:CTHA_RS12485
uniprot id: B3QX41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

517418:CTHA RS07755
gene id: 517418:CTHA_RS07755
uniprot id: B3QS02
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

517418:CTHA RS03245
gene id: 517418:CTHA_RS03245
uniprot id: B3QVP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS08180
gene id: 517418:CTHA_RS08180
uniprot id: B3QS76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

517418:CTHA RS08690
gene id: 517418:CTHA_RS08690
uniprot id: B3QSS0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

517418:CTHA RS08930
gene id: 517418:CTHA_RS08930
uniprot id: B3QT63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS04890
gene id: 517418:CTHA_RS04890
uniprot id: B3QXC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS12735
gene id: 517418:CTHA_RS12735
uniprot id: B3QX85
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

517418:CTHA RS13960
gene id: 517418:CTHA_RS13960
uniprot id: B3QYQ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

517418:CTHA RS07845
gene id: 517418:CTHA_RS07845
uniprot id: B3QS18
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

517418:CTHA RS05640
gene id: 517418:CTHA_RS05640
uniprot id: B3QY17
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS00885
gene id: 517418:CTHA_RS00885
uniprot id: B3QSZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS05160
gene id: 517418:CTHA_RS05160
uniprot id: B3QXH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS02495
gene id: 517418:CTHA_RS02495
uniprot id: B3QUQ1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

517418:CTHA RS13130
gene id: 517418:CTHA_RS13130
uniprot id: B3QXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS13335
gene id: 517418:CTHA_RS13335
uniprot id: B3QY44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

517418:CTHA RS06130
gene id: 517418:CTHA_RS06130
uniprot id: B3QYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

517418:CTHA RS04280
gene id: 517418:CTHA_RS04280
uniprot id: B3QWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

517418:CTHA RS03905
gene id: 517418:CTHA_RS03905
uniprot id: B3QWB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

517418:CTHA RS09710
gene id: 517418:CTHA_RS09710
uniprot id: B3QTW4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

517418:CTHA RS01490
gene id: 517418:CTHA_RS01490
uniprot id: B3QTL2
names: Similarity
messages: Belongs to the arsA ATPase family.

517418:CTHA RS04760
gene id: 517418:CTHA_RS04760
uniprot id: B3QXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

517418:CTHA RS07665
gene id: 517418:CTHA_RS07665
uniprot id: B3QRX7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

517418:CTHA RS05510
gene id: 517418:CTHA_RS05510
uniprot id: B3QXZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

517418:CTHA RS11965
gene id: 517418:CTHA_RS11965
uniprot id: B3QWI9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

517418:CTHA RS09205
gene id: 517418:CTHA_RS09205
uniprot id: B3QTB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

517418:CTHA RS05880
gene id: 517418:CTHA_RS05880
uniprot id: B3QYG2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

517418:CTHA RS08125
gene id: 517418:CTHA_RS08125
uniprot id: B3QS66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

517418:CTHA RS05705
gene id: 517418:CTHA_RS05705
uniprot id: B3QY30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

517418:CTHA RS13445
gene id: 517418:CTHA_RS13445
uniprot id: B3QY65
names: Similarity
messages: Belongs to the asparagine synthetase family.

517418:CTHA RS00275
gene id: 517418:CTHA_RS00275
uniprot id: B3QSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

517418:CTHA RS02590
gene id: 517418:CTHA_RS02590
uniprot id: B3QV22
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

517418:CTHA RS03915
gene id: 517418:CTHA_RS03915
uniprot id: B3QWB2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

517418:CTHA RS11990
gene id: 517418:CTHA_RS11990
uniprot id: B3QWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

517418:CTHA RS05695
gene id: 517418:CTHA_RS05695
uniprot id: B3QY28
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

517418:CTHA RS09365
gene id: 517418:CTHA_RS09365
uniprot id: B3QTP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

517418:CTHA RS10620
gene id: 517418:CTHA_RS10620
uniprot id: B3QUX9
names: Similarity
messages: Belongs to the Fur family.

517418:CTHA RS05380
gene id: 517418:CTHA_RS05380
uniprot id: B3QXW9
names: Similarity
messages: Belongs to the P(II) protein family.

517418:CTHA RS07125
gene id: 517418:CTHA_RS07125
uniprot id: B3QZD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

517418:CTHA RS08560
gene id: 517418:CTHA_RS08560
uniprot id: B3QSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

517418:CTHA RS05660
gene id: 517418:CTHA_RS05660
uniprot id: B3QY21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

517418:CTHA RS13540
gene id: 517418:CTHA_RS13540
uniprot id: B3QY84
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

517418:CTHA RS03085
gene id: 517418:CTHA_RS03085
uniprot id: B3QVB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

517418:CTHA RS01090
gene id: 517418:CTHA_RS01090
uniprot id: B3QTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

517418:CTHA RS11155
gene id: 517418:CTHA_RS11155
uniprot id: B3QVI5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

517418:CTHA RS04825
gene id: 517418:CTHA_RS04825
uniprot id: B3QXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS09060
gene id: 517418:CTHA_RS09060
uniprot id: B3QT88
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

517418:CTHA RS09415
gene id: 517418:CTHA_RS09415
uniprot id: B3QTQ6
names: Similarity
messages: Belongs to the Skp family.

517418:CTHA RS08965
gene id: 517418:CTHA_RS08965
uniprot id: B3QT70
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS01525
gene id: 517418:CTHA_RS01525
uniprot id: B3QTM0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

517418:CTHA RS10385
gene id: 517418:CTHA_RS10385
uniprot id: B3QUT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

517418:CTHA RS12885
gene id: 517418:CTHA_RS12885
uniprot id: B3QXK8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

517418:CTHA RS08830
gene id: 517418:CTHA_RS08830
uniprot id: B3QT44
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

517418:CTHA RS06145
gene id: 517418:CTHA_RS06145
uniprot id: B3QYL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

517418:CTHA RS01550
gene id: 517418:CTHA_RS01550
uniprot id: B3QTM5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

517418:CTHA RS00845
gene id: 517418:CTHA_RS00845
uniprot id: B3QSZ1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

517418:CTHA RS13120
gene id: 517418:CTHA_RS13120
uniprot id: B3QXQ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

517418:CTHA RS00600
gene id: 517418:CTHA_RS00600
uniprot id: B3QSU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

517418:CTHA RS00025
gene id: 517418:CTHA_RS00025
uniprot id: B3QRZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

517418:CTHA RS07760
gene id: 517418:CTHA_RS07760
uniprot id: B3QS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS03350
gene id: 517418:CTHA_RS03350
uniprot id: B3QVR4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

517418:CTHA RS06460
gene id: 517418:CTHA_RS06460
uniprot id: B3QZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

517418:CTHA RS00680
gene id: 517418:CTHA_RS00680
uniprot id: B3QSV9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

517418:CTHA RS11570
gene id: 517418:CTHA_RS11570
uniprot id: B3QW16
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

517418:CTHA RS11275
gene id: 517418:CTHA_RS11275
uniprot id: B3QVL0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

517418:CTHA RS02325
gene id: 517418:CTHA_RS02325
uniprot id: B3QUL7
names: Similarity
messages: Belongs to the UPF0251 family.

517418:CTHA RS05650
gene id: 517418:CTHA_RS05650
uniprot id: B3QY19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

517418:CTHA RS01650
gene id: 517418:CTHA_RS01650
uniprot id: B3QTZ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

517418:CTHA RS13550
gene id: 517418:CTHA_RS13550
uniprot id: B3QY86
names: Similarity
messages: Belongs to the LacAB/RpiB family.

517418:CTHA RS06955
gene id: 517418:CTHA_RS06955
uniprot id: B3QZA0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

517418:CTHA RS03515
gene id: 517418:CTHA_RS03515
uniprot id: B3QVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS05720
gene id: 517418:CTHA_RS05720
uniprot id: B3QYD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

517418:CTHA RS01095
gene id: 517418:CTHA_RS01095
uniprot id: B3QTD5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

517418:CTHA RS14495
gene id: 517418:CTHA_RS14495
uniprot id: B3QXZ8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

517418:CTHA RS02405
gene id: 517418:CTHA_RS02405
uniprot id: B3QUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

517418:CTHA RS10655
gene id: 517418:CTHA_RS10655
uniprot id: B3QUY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

517418:CTHA RS09360
gene id: 517418:CTHA_RS09360
uniprot id: B3QTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

517418:CTHA RS13860
gene id: 517418:CTHA_RS13860
uniprot id: B3QYN8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

517418:CTHA RS05715
gene id: 517418:CTHA_RS05715
uniprot id: B3QYD2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

517418:CTHA RS08665
gene id: 517418:CTHA_RS08665
uniprot id: B3QSR5
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

517418:CTHA RS09130
gene id: 517418:CTHA_RS09130
uniprot id: B3QTA0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

517418:CTHA RS11605
gene id: 517418:CTHA_RS11605
uniprot id: B3QW24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

517418:CTHA RS11465
gene id: 517418:CTHA_RS11465
uniprot id: B3QVZ4
names: Similarity
messages: Belongs to the Nth/MutY family.

517418:CTHA RS03655
gene id: 517418:CTHA_RS03655
uniprot id: B3QW64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS06040
gene id: 517418:CTHA_RS06040
uniprot id: B3QYJ4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

517418:CTHA RS01315
gene id: 517418:CTHA_RS01315
uniprot id: B3QTH8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

517418:CTHA RS06595
gene id: 517418:CTHA_RS06595
uniprot id: B3QZ30
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

517418:CTHA RS07585
gene id: 517418:CTHA_RS07585
uniprot id: B3QRW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

517418:CTHA RS10825
gene id: 517418:CTHA_RS10825
uniprot id: B3QV18
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS09510
gene id: 517418:CTHA_RS09510
uniprot id: B3QTS5
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS11255
gene id: 517418:CTHA_RS11255
uniprot id: B3QVK6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

517418:CTHA RS14160
gene id: 517418:CTHA_RS14160
uniprot id: B3QYU8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS06075
gene id: 517418:CTHA_RS06075
uniprot id: B3QYK1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS09875
gene id: 517418:CTHA_RS09875
uniprot id: B3QU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

517418:CTHA RS08455
gene id: 517418:CTHA_RS08455
uniprot id: B3QSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

517418:CTHA RS10760
gene id: 517418:CTHA_RS10760
uniprot id: B3QV06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

517418:CTHA RS03395
gene id: 517418:CTHA_RS03395
uniprot id: B3QVS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

517418:CTHA RS11610
gene id: 517418:CTHA_RS11610
uniprot id: B3QW25
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS04670
gene id: 517418:CTHA_RS04670
uniprot id: B3QWZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS01810
gene id: 517418:CTHA_RS01810
uniprot id: B3QU23
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

517418:CTHA RS06915
gene id: 517418:CTHA_RS06915
uniprot id: B3QZ92
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

517418:CTHA RS00725
gene id: 517418:CTHA_RS00725
uniprot id: B3QSW8
names: Similarity
messages: Belongs to the GcvH family.

517418:CTHA RS07950
gene id: 517418:CTHA_RS07950
uniprot id: B3QS35
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

517418:CTHA RS04040
gene id: 517418:CTHA_RS04040
uniprot id: B3QWC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

517418:CTHA RS11150
gene id: 517418:CTHA_RS11150
uniprot id: B3QVI4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS06815
gene id: 517418:CTHA_RS06815
uniprot id: B3QZ72
names: Similarity
messages: Belongs to the Fur family.

517418:CTHA RS12980
gene id: 517418:CTHA_RS12980
uniprot id: B3QXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

517418:CTHA RS05790
gene id: 517418:CTHA_RS05790
uniprot id: B3QYE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

517418:CTHA RS08185
gene id: 517418:CTHA_RS08185
uniprot id: B3QS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

517418:CTHA RS02065
gene id: 517418:CTHA_RS02065
uniprot id: B3QU75
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS10565
gene id: 517418:CTHA_RS10565
uniprot id: B3QUX0
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS11135
gene id: 517418:CTHA_RS11135
uniprot id: B3QVI1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

517418:CTHA RS00550
gene id: 517418:CTHA_RS00550
uniprot id: B3QSI7
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

517418:CTHA RS04800
gene id: 517418:CTHA_RS04800
uniprot id: B3QXB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS03040
gene id: 517418:CTHA_RS03040
uniprot id: B3QVB0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

517418:CTHA RS09400
gene id: 517418:CTHA_RS09400
uniprot id: B3QTQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

517418:CTHA RS05495
gene id: 517418:CTHA_RS05495
uniprot id: B3QXZ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

517418:CTHA RS05070
gene id: 517418:CTHA_RS05070
uniprot id: B3QXG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

517418:CTHA RS05800
gene id: 517418:CTHA_RS05800
uniprot id: B3QYE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

517418:CTHA RS06440
gene id: 517418:CTHA_RS06440
uniprot id: B3QZ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

517418:CTHA RS07205
gene id: 517418:CTHA_RS07205
uniprot id: B3QZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

517418:CTHA RS10920
gene id: 517418:CTHA_RS10920
uniprot id: B3QVD8
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS02960
gene id: 517418:CTHA_RS02960
uniprot id: B3QV95
names: Similarity
messages: Belongs to the arsA ATPase family.

517418:CTHA RS04960
gene id: 517418:CTHA_RS04960
uniprot id: B3QXE1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

517418:CTHA RS14365
gene id: 517418:CTHA_RS14365
uniprot id: B3QV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

517418:CTHA RS10125
gene id: 517418:CTHA_RS10125
uniprot id: B3QUE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

517418:CTHA RS07290
gene id: 517418:CTHA_RS07290
uniprot id: B3QRQ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

517418:CTHA RS10295
gene id: 517418:CTHA_RS10295
uniprot id: B3QUR9
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

517418:CTHA RS10020
gene id: 517418:CTHA_RS10020
uniprot id: B3QUC1
names: Similarity
messages: Belongs to the thioredoxin family.

517418:CTHA RS06030
gene id: 517418:CTHA_RS06030
uniprot id: B3QYJ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

517418:CTHA RS12385
gene id: 517418:CTHA_RS12385
uniprot id: B3QX21
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

517418:CTHA RS01120
gene id: 517418:CTHA_RS01120
uniprot id: B3QTD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS07345
gene id: 517418:CTHA_RS07345
uniprot id: B3QRR5
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS08090
gene id: 517418:CTHA_RS08090
uniprot id: B3QS60
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

517418:CTHA RS04320
gene id: 517418:CTHA_RS04320
uniprot id: B3QWT2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS01270
gene id: 517418:CTHA_RS01270
uniprot id: B3QTG9
names: Similarity
messages: Belongs to the universal stress protein A family.

517418:CTHA RS00985
gene id: 517418:CTHA_RS00985
uniprot id: B3QT18
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

517418:CTHA RS06325
gene id: 517418:CTHA_RS06325
uniprot id: B3QYX8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

517418:CTHA RS01640
gene id: 517418:CTHA_RS01640
uniprot id: B3QTZ2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

517418:CTHA RS07525
gene id: 517418:CTHA_RS07525
uniprot id: B3QRU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS07135
gene id: 517418:CTHA_RS07135
uniprot id: B3QZD6
names: Similarity
messages: Belongs to the TrpC family.

517418:CTHA RS00310
gene id: 517418:CTHA_RS00310
uniprot id: B3QSE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS02970
gene id: 517418:CTHA_RS02970
uniprot id: B3QV97
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

517418:CTHA RS11775
gene id: 517418:CTHA_RS11775
uniprot id: B3QWF3
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

517418:CTHA RS06195
gene id: 517418:CTHA_RS06195
uniprot id: B3QYM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS11970
gene id: 517418:CTHA_RS11970
uniprot id: B3QWJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

517418:CTHA RS13855
gene id: 517418:CTHA_RS13855
uniprot id: B3QYN7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

517418:CTHA RS05620
gene id: 517418:CTHA_RS05620
uniprot id: B3QY13
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

517418:CTHA RS11000
gene id: 517418:CTHA_RS11000
uniprot id: B3QVF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

517418:CTHA RS02425
gene id: 517418:CTHA_RS02425
uniprot id: B3QUN7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

517418:CTHA RS01245
gene id: 517418:CTHA_RS01245
uniprot id: B3QTG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

517418:CTHA RS09140
gene id: 517418:CTHA_RS09140
uniprot id: B3QTA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS08100
gene id: 517418:CTHA_RS08100
uniprot id: B3QS62
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

517418:CTHA RS02005
gene id: 517418:CTHA_RS02005
uniprot id: B3QU63
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

517418:CTHA RS03135
gene id: 517418:CTHA_RS03135
uniprot id: B3QVM5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

517418:CTHA RS08800
gene id: 517418:CTHA_RS08800
uniprot id: B3QT39
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS11945
gene id: 517418:CTHA_RS11945
uniprot id: B3QWI6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

517418:CTHA RS00495
gene id: 517418:CTHA_RS00495
uniprot id: B3QSH7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

517418:CTHA RS11785
gene id: 517418:CTHA_RS11785
uniprot id: B3QWF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

517418:CTHA RS05655
gene id: 517418:CTHA_RS05655
uniprot id: B3QY20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

517418:CTHA RS14335
gene id: 517418:CTHA_RS14335
uniprot id: B3QUM2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

517418:CTHA RS06825
gene id: 517418:CTHA_RS06825
uniprot id: B3QZ74
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

517418:CTHA RS11665
gene id: 517418:CTHA_RS11665
uniprot id: B3QW36
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

517418:CTHA RS09575
gene id: 517418:CTHA_RS09575
uniprot id: B3QTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

517418:CTHA RS10360
gene id: 517418:CTHA_RS10360
uniprot id: B3QUT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

517418:CTHA RS13325
gene id: 517418:CTHA_RS13325
uniprot id: B3QY42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS00910
gene id: 517418:CTHA_RS00910
uniprot id: B3QT03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

517418:CTHA RS10585
gene id: 517418:CTHA_RS10585
uniprot id: B3QUX4
names: Similarity
messages: Belongs to the asparagine synthetase family.

517418:CTHA RS02270
gene id: 517418:CTHA_RS02270
uniprot id: B3QUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS12135
gene id: 517418:CTHA_RS12135
uniprot id: B3QWM3
names: Similarity
messages: Belongs to the ferrochelatase family.

517418:CTHA RS10320
gene id: 517418:CTHA_RS10320
uniprot id: B3QUS4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

517418:CTHA RS08945
gene id: 517418:CTHA_RS08945
uniprot id: B3QT66
names: Similarity
messages: Belongs to the UPF0047 family.

517418:CTHA RS01215
gene id: 517418:CTHA_RS01215
uniprot id: B3QTF8
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS13355
gene id: 517418:CTHA_RS13355
uniprot id: B3QY48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS08955
gene id: 517418:CTHA_RS08955
uniprot id: B3QT68
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

517418:CTHA RS10800
gene id: 517418:CTHA_RS10800
uniprot id: B3QV13
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS13020
gene id: 517418:CTHA_RS13020
uniprot id: B3QXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

517418:CTHA RS10695
gene id: 517418:CTHA_RS10695
uniprot id: B3QUZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

517418:CTHA RS10820
gene id: 517418:CTHA_RS10820
uniprot id: B3QV17
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

517418:CTHA RS01045
gene id: 517418:CTHA_RS01045
uniprot id: B3QT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS05780
gene id: 517418:CTHA_RS05780
uniprot id: B3QYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

517418:CTHA RS04795
gene id: 517418:CTHA_RS04795
uniprot id: B3QXA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

517418:CTHA RS06920
gene id: 517418:CTHA_RS06920
uniprot id: B3QZ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

517418:CTHA RS02725
gene id: 517418:CTHA_RS02725
uniprot id: B3QV49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

517418:CTHA RS09660
gene id: 517418:CTHA_RS09660
uniprot id: B3QTV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

517418:CTHA RS01695
gene id: 517418:CTHA_RS01695
uniprot id: B3QU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

517418:CTHA RS01265
gene id: 517418:CTHA_RS01265
uniprot id: B3QTG8
names: Similarity
messages: Belongs to the CIA30 family.

517418:CTHA RS12115
gene id: 517418:CTHA_RS12115
uniprot id: B3QWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

517418:CTHA RS06300
gene id: 517418:CTHA_RS06300
uniprot id: B3QYX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

517418:CTHA RS01310
gene id: 517418:CTHA_RS01310
uniprot id: B3QTH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

517418:CTHA RS12665
gene id: 517418:CTHA_RS12665
uniprot id: B3QX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

517418:CTHA RS03165
gene id: 517418:CTHA_RS03165
uniprot id: B3QVN0
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

517418:CTHA RS12095
gene id: 517418:CTHA_RS12095
uniprot id: B3QWL4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS09230
gene id: 517418:CTHA_RS09230
uniprot id: B3QTB9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

517418:CTHA RS12955
gene id: 517418:CTHA_RS12955
uniprot id: B3QXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

517418:CTHA RS06850
gene id: 517418:CTHA_RS06850
uniprot id: B3QZ79
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

517418:CTHA RS13435
gene id: 517418:CTHA_RS13435
uniprot id: B3QY63
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

517418:CTHA RS09045
gene id: 517418:CTHA_RS09045
uniprot id: B3QT85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

517418:CTHA RS05795
gene id: 517418:CTHA_RS05795
uniprot id: B3QYE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

517418:CTHA RS08760
gene id: 517418:CTHA_RS08760
uniprot id: B3QST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

517418:CTHA RS11930
gene id: 517418:CTHA_RS11930
uniprot id: B3QWI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS04305
gene id: 517418:CTHA_RS04305
uniprot id: B3QWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

517418:CTHA RS10155
gene id: 517418:CTHA_RS10155
uniprot id: B3QUE7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

517418:CTHA RS08530
gene id: 517418:CTHA_RS08530
uniprot id: B3QSN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS12890
gene id: 517418:CTHA_RS12890
uniprot id: B3QXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

517418:CTHA RS11865
gene id: 517418:CTHA_RS11865
uniprot id: B3QWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

517418:CTHA RS00145
gene id: 517418:CTHA_RS00145
uniprot id: B3QSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

517418:CTHA RS07415
gene id: 517418:CTHA_RS07415
uniprot id: B3QRS9
names: Similarity
messages: Belongs to the UPF0145 family.

517418:CTHA RS03145
gene id: 517418:CTHA_RS03145
uniprot id: B3QVM6
names: Similarity
messages: Belongs to the citrate synthase family.

517418:CTHA RS09570
gene id: 517418:CTHA_RS09570
uniprot id: B3QTT5
names: Similarity
messages: Belongs to the HypD family.

517418:CTHA RS05895
gene id: 517418:CTHA_RS05895
uniprot id: B3QYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

517418:CTHA RS13500
gene id: 517418:CTHA_RS13500
uniprot id: B3QY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

517418:CTHA RS05675
gene id: 517418:CTHA_RS05675
uniprot id: B3QY24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

517418:CTHA RS10450
gene id: 517418:CTHA_RS10450
uniprot id: B3QUV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

517418:CTHA RS03020
gene id: 517418:CTHA_RS03020
uniprot id: B3QVA6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

517418:CTHA RS12235
gene id: 517418:CTHA_RS12235
uniprot id: B3QWP0
names: Similarity
messages: Belongs to the peptidase S41A family.

517418:CTHA RS02890
gene id: 517418:CTHA_RS02890
uniprot id: B3QV82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

517418:CTHA RS03585
gene id: 517418:CTHA_RS03585
uniprot id: B3QVV8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

517418:CTHA RS00515
gene id: 517418:CTHA_RS00515
uniprot id: B3QSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

517418:CTHA RS01115
gene id: 517418:CTHA_RS01115
uniprot id: B3QTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

517418:CTHA RS07980
gene id: 517418:CTHA_RS07980
uniprot id: B3QS41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS04855
gene id: 517418:CTHA_RS04855
uniprot id: B3QXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

517418:CTHA RS00900
gene id: 517418:CTHA_RS00900
uniprot id: B3QT01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

517418:CTHA RS04350
gene id: 517418:CTHA_RS04350
uniprot id: B3QWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

517418:CTHA RS10150
gene id: 517418:CTHA_RS10150
uniprot id: B3QUE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS05810
gene id: 517418:CTHA_RS05810
uniprot id: B3QYF1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

517418:CTHA RS09030
gene id: 517418:CTHA_RS09030
uniprot id: B3QT82
names: Similarity
messages: Belongs to the peptidase S8 family.

517418:CTHA RS07195
gene id: 517418:CTHA_RS07195
uniprot id: B3QZE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

517418:CTHA RS07750
gene id: 517418:CTHA_RS07750
uniprot id: B3QS01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

517418:CTHA RS12960
gene id: 517418:CTHA_RS12960
uniprot id: B3QXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS04950
gene id: 517418:CTHA_RS04950
uniprot id: B3QXE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS11730
gene id: 517418:CTHA_RS11730
uniprot id: B3QW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS13305
gene id: 517418:CTHA_RS13305
uniprot id: B3QY38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS13350
gene id: 517418:CTHA_RS13350
uniprot id: B3QY47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS01065
gene id: 517418:CTHA_RS01065
uniprot id: B3QT32
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

517418:CTHA RS04325
gene id: 517418:CTHA_RS04325
uniprot id: B3QWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

517418:CTHA RS10700
gene id: 517418:CTHA_RS10700
uniprot id: B3QUZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS11890
gene id: 517418:CTHA_RS11890
uniprot id: B3QWH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

517418:CTHA RS02310
gene id: 517418:CTHA_RS02310
uniprot id: B3QUL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

517418:CTHA RS14450
gene id: 517418:CTHA_RS14450
uniprot id: B3QWZ6
names: Similarity
messages: Belongs to the peptidase S24 family.

517418:CTHA RS08065
gene id: 517418:CTHA_RS08065
uniprot id: B3QS56
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

517418:CTHA RS13785
gene id: 517418:CTHA_RS13785
uniprot id: B3QYD1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

517418:CTHA RS00400
gene id: 517418:CTHA_RS00400
uniprot id: B3QSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

517418:CTHA RS02460
gene id: 517418:CTHA_RS02460
uniprot id: B3QUP5
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

517418:CTHA RS04395
gene id: 517418:CTHA_RS04395
uniprot id: B3QWU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

517418:CTHA RS12070
gene id: 517418:CTHA_RS12070
uniprot id: B3QWK9
names: Similarity
messages: Belongs to the fructosamine kinase family.

517418:CTHA RS08795
gene id: 517418:CTHA_RS08795
uniprot id: B3QT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

517418:CTHA RS00315
gene id: 517418:CTHA_RS00315
uniprot id: B3QSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

517418:CTHA RS09630
gene id: 517418:CTHA_RS09630
uniprot id: B3QTU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

517418:CTHA RS08580
gene id: 517418:CTHA_RS08580
uniprot id: B3QSP8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

517418:CTHA RS03265
gene id: 517418:CTHA_RS03265
uniprot id: B3QVP8
names: Similarity
messages: Belongs to the arsA ATPase family.

517418:CTHA RS00065
gene id: 517418:CTHA_RS00065
uniprot id: B3QS95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS09440
gene id: 517418:CTHA_RS09440
uniprot id: B3QTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

517418:CTHA RS10790
gene id: 517418:CTHA_RS10790
uniprot id: B3QV11
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

517418:CTHA RS08720
gene id: 517418:CTHA_RS08720
uniprot id: B3QSS6
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS13565
gene id: 517418:CTHA_RS13565
uniprot id: B3QY89
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS04210
gene id: 517418:CTHA_RS04210
uniprot id: B3QWR1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

517418:CTHA RS01990
gene id: 517418:CTHA_RS01990
uniprot id: B3QU60
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS11130
gene id: 517418:CTHA_RS11130
uniprot id: B3QVI0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

517418:CTHA RS01070
gene id: 517418:CTHA_RS01070
uniprot id: B3QT33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

517418:CTHA RS04450
gene id: 517418:CTHA_RS04450
uniprot id: B3QWV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

517418:CTHA RS05745
gene id: 517418:CTHA_RS05745
uniprot id: B3QYD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

517418:CTHA RS03600
gene id: 517418:CTHA_RS03600
uniprot id: B3QVW1
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS06150
gene id: 517418:CTHA_RS06150
uniprot id: B3QYL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

517418:CTHA RS00040
gene id: 517418:CTHA_RS00040
uniprot id: B3QS90
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS07645
gene id: 517418:CTHA_RS07645
uniprot id: B3QRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

517418:CTHA RS02875
gene id: 517418:CTHA_RS02875
uniprot id: B3QV79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

517418:CTHA RS04370
gene id: 517418:CTHA_RS04370
uniprot id: B3QWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

517418:CTHA RS07105
gene id: 517418:CTHA_RS07105
uniprot id: B3QZD0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

517418:CTHA RS13470
gene id: 517418:CTHA_RS13470
uniprot id: B3QY70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

517418:CTHA RS00300
gene id: 517418:CTHA_RS00300
uniprot id: B3QSE0
names: Similarity
messages: Belongs to the peptidase M16 family.

517418:CTHA RS01020
gene id: 517418:CTHA_RS01020
uniprot id: B3QT24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

517418:CTHA RS04820
gene id: 517418:CTHA_RS04820
uniprot id: B3QXB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

517418:CTHA RS11910
gene id: 517418:CTHA_RS11910
uniprot id: B3QWH9
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS01335
gene id: 517418:CTHA_RS01335
uniprot id: B3QTI2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

517418:CTHA RS09595
gene id: 517418:CTHA_RS09595
uniprot id: B3QTU0
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

517418:CTHA RS00210
gene id: 517418:CTHA_RS00210
uniprot id: B3QSC3
names: Similarity
messages: Belongs to the glutamine synthetase family.

517418:CTHA RS13545
gene id: 517418:CTHA_RS13545
uniprot id: B3QY85
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

517418:CTHA RS06220
gene id: 517418:CTHA_RS06220
uniprot id: B3QYW0
names: Similarity
messages: Belongs to the CutA family.

517418:CTHA RS04340
gene id: 517418:CTHA_RS04340
uniprot id: B3QWT6
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS01690
gene id: 517418:CTHA_RS01690
uniprot id: B3QU02
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

517418:CTHA RS12365
gene id: 517418:CTHA_RS12365
uniprot id: B3QX17
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

517418:CTHA RS02280
gene id: 517418:CTHA_RS02280
uniprot id: B3QUK9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

517418:CTHA RS12830
gene id: 517418:CTHA_RS12830
uniprot id: B3QXJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

517418:CTHA RS06375
gene id: 517418:CTHA_RS06375
uniprot id: B3QYY8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

517418:CTHA RS07160
gene id: 517418:CTHA_RS07160
uniprot id: B3QZE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

517418:CTHA RS01900
gene id: 517418:CTHA_RS01900
uniprot id: B3QU42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

517418:CTHA RS13920
gene id: 517418:CTHA_RS13920
uniprot id: B3QYP9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

517418:CTHA RS06720
gene id: 517418:CTHA_RS06720
uniprot id: B3QZ55
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

517418:CTHA RS05690
gene id: 517418:CTHA_RS05690
uniprot id: B3QY27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

517418:CTHA RS08590
gene id: 517418:CTHA_RS08590
uniprot id: B3QSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS12065
gene id: 517418:CTHA_RS12065
uniprot id: B3QWK8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

517418:CTHA RS02070
gene id: 517418:CTHA_RS02070
uniprot id: B3QU76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS10175
gene id: 517418:CTHA_RS10175
uniprot id: B3QUF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

517418:CTHA RS01305
gene id: 517418:CTHA_RS01305
uniprot id: B3QTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

517418:CTHA RS08865
gene id: 517418:CTHA_RS08865
uniprot id: B3QT51
names: Similarity
messages: Belongs to the AlaDH/PNT family.

517418:CTHA RS04865
gene id: 517418:CTHA_RS04865
uniprot id: B3QXC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS10535
gene id: 517418:CTHA_RS10535
uniprot id: B3QUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

517418:CTHA RS13145
gene id: 517418:CTHA_RS13145
uniprot id: B3QXQ7
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS06165
gene id: 517418:CTHA_RS06165
uniprot id: B3QYL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

517418:CTHA RS03720
gene id: 517418:CTHA_RS03720
uniprot id: B3QW76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS05605
gene id: 517418:CTHA_RS05605
uniprot id: B3QY10
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

517418:CTHA RS06635
gene id: 517418:CTHA_RS06635
uniprot id: B3QZ38
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

517418:CTHA RS06550
gene id: 517418:CTHA_RS06550
uniprot id: B3QZ22
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS05670
gene id: 517418:CTHA_RS05670
uniprot id: B3QY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

517418:CTHA RS06950
gene id: 517418:CTHA_RS06950
uniprot id: B3QZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS04090
gene id: 517418:CTHA_RS04090
uniprot id: B3QWD8
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS13315
gene id: 517418:CTHA_RS13315
uniprot id: B3QY40
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS09145
gene id: 517418:CTHA_RS09145
uniprot id: B3QTA3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

517418:CTHA RS12230
gene id: 517418:CTHA_RS12230
uniprot id: B3QWN9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

517418:CTHA RS02750
gene id: 517418:CTHA_RS02750
uniprot id: B3QV54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

517418:CTHA RS00590
gene id: 517418:CTHA_RS00590
uniprot id: B3QSU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

517418:CTHA RS10810
gene id: 517418:CTHA_RS10810
uniprot id: B3QV15
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

517418:CTHA RS01865
gene id: 517418:CTHA_RS01865
uniprot id: B3QU34
names: Similarity
messages: Belongs to the asparagine synthetase family.

517418:CTHA RS10340
gene id: 517418:CTHA_RS10340
uniprot id: B3QUS8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

517418:CTHA RS06630
gene id: 517418:CTHA_RS06630
uniprot id: B3QZ37
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

517418:CTHA RS01325
gene id: 517418:CTHA_RS01325
uniprot id: B3QTI0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

517418:CTHA RS05390
gene id: 517418:CTHA_RS05390
uniprot id: B3QXX1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

517418:CTHA RS10355
gene id: 517418:CTHA_RS10355
uniprot id: B3QUT1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

517418:CTHA RS00740
gene id: 517418:CTHA_RS00740
uniprot id: B3QSX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

517418:CTHA RS11690
gene id: 517418:CTHA_RS11690
uniprot id: B3QW41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

517418:CTHA RS13710
gene id: 517418:CTHA_RS13710
uniprot id: B3QYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

517418:CTHA RS04730
gene id: 517418:CTHA_RS04730
uniprot id: B3QX98
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

517418:CTHA RS02855
gene id: 517418:CTHA_RS02855
uniprot id: B3QV75
names: Similarity
messages: Belongs to the UPF0234 family.

517418:CTHA RS07075
gene id: 517418:CTHA_RS07075
uniprot id: B3QZC4
names: Similarity
messages: Belongs to the MoaD family.

517418:CTHA RS04560
gene id: 517418:CTHA_RS04560
uniprot id: B3QWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

517418:CTHA RS13875
gene id: 517418:CTHA_RS13875
uniprot id: B3QYP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS06200
gene id: 517418:CTHA_RS06200
uniprot id: B3QYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

517418:CTHA RS06320
gene id: 517418:CTHA_RS06320
uniprot id: B3QYX7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

517418:CTHA RS02990
gene id: 517418:CTHA_RS02990
uniprot id: B3QVA1
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS04150
gene id: 517418:CTHA_RS04150
uniprot id: B3QWF0
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

517418:CTHA RS09100
gene id: 517418:CTHA_RS09100
uniprot id: B3QT95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS12745
gene id: 517418:CTHA_RS12745
uniprot id: B3QX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS02615
gene id: 517418:CTHA_RS02615
uniprot id: B3QV27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

517418:CTHA RS10595
gene id: 517418:CTHA_RS10595
uniprot id: B3QUX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS03255
gene id: 517418:CTHA_RS03255
uniprot id: B3QVP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

517418:CTHA RS14185
gene id: 517418:CTHA_RS14185
uniprot id: B3QYV3
names: Similarity
messages: Belongs to the UPF0045 family.

517418:CTHA RS09680
gene id: 517418:CTHA_RS09680
uniprot id: B3QTV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS10715
gene id: 517418:CTHA_RS10715
uniprot id: B3QUZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

517418:CTHA RS02395
gene id: 517418:CTHA_RS02395
uniprot id: B3QUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

517418:CTHA RS02835
gene id: 517418:CTHA_RS02835
uniprot id: B3QV71
names: Similarity
messages: Belongs to the UPF0166 family.

517418:CTHA RS03790
gene id: 517418:CTHA_RS03790
uniprot id: B3QW89
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

517418:CTHA RS06415
gene id: 517418:CTHA_RS06415
uniprot id: B3QYZ5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

517418:CTHA RS07210
gene id: 517418:CTHA_RS07210
uniprot id: B3QZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

517418:CTHA RS12055
gene id: 517418:CTHA_RS12055
uniprot id: B3QWK6
names: Similarity
messages: Belongs to the peptidase M24B family.

517418:CTHA RS09860
gene id: 517418:CTHA_RS09860
uniprot id: B3QU91
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

517418:CTHA RS02760
gene id: 517418:CTHA_RS02760
uniprot id: B3QV56
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

517418:CTHA RS07435
gene id: 517418:CTHA_RS07435
uniprot id: B3QRT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS00455
gene id: 517418:CTHA_RS00455
uniprot id: B3QSH0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

517418:CTHA RS12120
gene id: 517418:CTHA_RS12120
uniprot id: B3QWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

517418:CTHA RS08335
gene id: 517418:CTHA_RS08335
uniprot id: B3QSK1
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS03290
gene id: 517418:CTHA_RS03290
uniprot id: B3QVQ3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

517418:CTHA RS07310
gene id: 517418:CTHA_RS07310
uniprot id: B3QRQ8
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

517418:CTHA RS09645
gene id: 517418:CTHA_RS09645
uniprot id: B3QTV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

517418:CTHA RS11580
gene id: 517418:CTHA_RS11580
uniprot id: B3QW18
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

517418:CTHA RS09095
gene id: 517418:CTHA_RS09095
uniprot id: B3QT94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

517418:CTHA RS08570
gene id: 517418:CTHA_RS08570
uniprot id: B3QSP6
names: Similarity
messages: Belongs to the hemerythrin family.

517418:CTHA RS10005
gene id: 517418:CTHA_RS10005
uniprot id: B3QUB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

517418:CTHA RS05625
gene id: 517418:CTHA_RS05625
uniprot id: B3QY14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

517418:CTHA RS07445
gene id: 517418:CTHA_RS07445
uniprot id: B3QRT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

517418:CTHA RS03635
gene id: 517418:CTHA_RS03635
uniprot id: B3QW60
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

517418:CTHA RS00460
gene id: 517418:CTHA_RS00460
uniprot id: B3QSH1
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS04345
gene id: 517418:CTHA_RS04345
uniprot id: B3QWT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

517418:CTHA RS08170
gene id: 517418:CTHA_RS08170
uniprot id: B3QS74
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

517418:CTHA RS14265
gene id: 517418:CTHA_RS14265
uniprot id: B3QT23
names: Similarity
messages: Belongs to the phosphopentomutase family.

517418:CTHA RS11455
gene id: 517418:CTHA_RS11455
uniprot id: B3QVZ2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

517418:CTHA RS03280
gene id: 517418:CTHA_RS03280
uniprot id: B3QVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

517418:CTHA RS05460
gene id: 517418:CTHA_RS05460
uniprot id: B3QXY4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

517418:CTHA RS10440
gene id: 517418:CTHA_RS10440
uniprot id: B3QUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

517418:CTHA RS03185
gene id: 517418:CTHA_RS03185
uniprot id: B3QVN4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS14320
gene id: 517418:CTHA_RS14320
uniprot id: B3QUK0
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS04260
gene id: 517418:CTHA_RS04260
uniprot id: B3QWS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

517418:CTHA RS11550
gene id: 517418:CTHA_RS11550
uniprot id: B3QW12
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

517418:CTHA RS07090
gene id: 517418:CTHA_RS07090
uniprot id: B3QZC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS09390
gene id: 517418:CTHA_RS09390
uniprot id: B3QTQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

517418:CTHA RS02690
gene id: 517418:CTHA_RS02690
uniprot id: B3QV42
names: Similarity
messages: Belongs to the phosphohexose mutase family.

517418:CTHA RS13320
gene id: 517418:CTHA_RS13320
uniprot id: B3QY41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS09650
gene id: 517418:CTHA_RS09650
uniprot id: B3QTV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

517418:CTHA RS00180
gene id: 517418:CTHA_RS00180
uniprot id: B3QSB6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

517418:CTHA RS04745
gene id: 517418:CTHA_RS04745
uniprot id: B3QXA1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

517418:CTHA RS12725
gene id: 517418:CTHA_RS12725
uniprot id: B3QX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS02995
gene id: 517418:CTHA_RS02995
uniprot id: B3QVA2
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS09580
gene id: 517418:CTHA_RS09580
uniprot id: B3QTT7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

517418:CTHA RS06870
gene id: 517418:CTHA_RS06870
uniprot id: B3QZ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS08340
gene id: 517418:CTHA_RS08340
uniprot id: B3QSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

517418:CTHA RS09475
gene id: 517418:CTHA_RS09475
uniprot id: B3QTR8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

517418:CTHA RS09935
gene id: 517418:CTHA_RS09935
uniprot id: B3QUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS02205
gene id: 517418:CTHA_RS02205
uniprot id: B3QUJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

517418:CTHA RS01135
gene id: 517418:CTHA_RS01135
uniprot id: B3QTE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

517418:CTHA RS03765
gene id: 517418:CTHA_RS03765
uniprot id: B3QW85
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

517418:CTHA RS11485
gene id: 517418:CTHA_RS11485
uniprot id: B3QVZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

517418:CTHA RS12580
gene id: 517418:CTHA_RS12580
uniprot id: B3QX58
names: Similarity
messages: Belongs to the DNA photolyase family.

517418:CTHA RS05765
gene id: 517418:CTHA_RS05765
uniprot id: B3QYE1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

517418:CTHA RS11100
gene id: 517418:CTHA_RS11100
uniprot id: B3QVH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

517418:CTHA RS04505
gene id: 517418:CTHA_RS04505
uniprot id: B3QWW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

517418:CTHA RS11620
gene id: 517418:CTHA_RS11620
uniprot id: B3QW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

517418:CTHA RS02400
gene id: 517418:CTHA_RS02400
uniprot id: B3QUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

517418:CTHA RS13410
gene id: 517418:CTHA_RS13410
uniprot id: B3QY58
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

517418:CTHA RS09665
gene id: 517418:CTHA_RS09665
uniprot id: B3QTV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

517418:CTHA RS08200
gene id: 517418:CTHA_RS08200
uniprot id: B3QS80
names: Similarity
messages: Belongs to the peptidase S49 family.

517418:CTHA RS13230
gene id: 517418:CTHA_RS13230
uniprot id: B3QXS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

517418:CTHA RS03640
gene id: 517418:CTHA_RS03640
uniprot id: B3QW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

517418:CTHA RS10230
gene id: 517418:CTHA_RS10230
uniprot id: B3QUF9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

517418:CTHA RS02465
gene id: 517418:CTHA_RS02465
uniprot id: B3QUP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

517418:CTHA RS03675
gene id: 517418:CTHA_RS03675
uniprot id: B3QW67
names: Similarity
messages: Belongs to the glutamate synthase family.

517418:CTHA RS05755
gene id: 517418:CTHA_RS05755
uniprot id: B3QYD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

517418:CTHA RS03690
gene id: 517418:CTHA_RS03690
uniprot id: B3QW70
names: Subcellular Location Annotation
messages: Cytoplasm

517418:CTHA RS06465
gene id: 517418:CTHA_RS06465
uniprot id: B3QZ05
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

517418:CTHA RS09370
gene id: 517418:CTHA_RS09370
uniprot id: B3QTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

517418:CTHA RS10045
gene id: 517418:CTHA_RS10045
uniprot id: B3QUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

517418:CTHA RS08175
gene id: 517418:CTHA_RS08175
uniprot id: B3QS75
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

517418:CTHA RS10610
gene id: 517418:CTHA_RS10610
uniprot id: B3QUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

517418:CTHA RS12000
gene id: 517418:CTHA_RS12000
uniprot id: B3QWJ5
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

517418:CTHA RS07410
gene id: 517418:CTHA_RS07410
uniprot id: B3QRS8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

517418:CTHA RS05025
gene id: 517418:CTHA_RS05025
uniprot id: B3QXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS04555
gene id: 517418:CTHA_RS04555
uniprot id: B3QWX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

517418:CTHA RS12685
gene id: 517418:CTHA_RS12685
uniprot id: B3QX78
names: Similarity
messages: Belongs to the Fur family.

517418:CTHA RS09605
gene id: 517418:CTHA_RS09605
uniprot id: B3QTU2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

517418:CTHA RS03925
gene id: 517418:CTHA_RS03925
uniprot id: B3QWB4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS04455
gene id: 517418:CTHA_RS04455
uniprot id: B3QWV8
names: Similarity
messages: Belongs to the universal stress protein A family.

517418:CTHA RS14370
gene id: 517418:CTHA_RS14370
uniprot id: B3QV43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

517418:CTHA RS06860
gene id: 517418:CTHA_RS06860
uniprot id: B3QZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

517418:CTHA RS07320
gene id: 517418:CTHA_RS07320
uniprot id: B3QRR0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

517418:CTHA RS03330
gene id: 517418:CTHA_RS03330
uniprot id: B3QVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

517418:CTHA RS09505
gene id: 517418:CTHA_RS09505
uniprot id: B3QTS4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

517418:CTHA RS01510
gene id: 517418:CTHA_RS01510
uniprot id: B3QTL7
names: Similarity
messages: Belongs to the arsA ATPase family.

517418:CTHA RS07705
gene id: 517418:CTHA_RS07705
uniprot id: B3QRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

517418:CTHA RS08725
gene id: 517418:CTHA_RS08725
uniprot id: B3QSS7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

517418:CTHA RS11780
gene id: 517418:CTHA_RS11780
uniprot id: B3QWF4
names: Similarity
messages: Belongs to the RecJ family.

517418:CTHA RS09545
gene id: 517418:CTHA_RS09545
uniprot id: B3QTT1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

517418:CTHA RS08545
gene id: 517418:CTHA_RS08545
uniprot id: B3QSP2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

517418:CTHA RS05785
gene id: 517418:CTHA_RS05785
uniprot id: B3QYE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

517418:CTHA RS03470
gene id: 517418:CTHA_RS03470
uniprot id: B3QVT7
names: Similarity
messages: Belongs to the fabD family.

517418:CTHA RS08550
gene id: 517418:CTHA_RS08550
uniprot id: B3QSP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

517418:CTHA RS07850
gene id: 517418:CTHA_RS07850
uniprot id: B3QS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

517418:CTHA RS09380
gene id: 517418:CTHA_RS09380
uniprot id: B3QTP9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

517418:CTHA RS04625
gene id: 517418:CTHA_RS04625
uniprot id: B3QWY9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS06005
gene id: 517418:CTHA_RS06005
uniprot id: B3QYI7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

517418:CTHA RS07465
gene id: 517418:CTHA_RS07465
uniprot id: B3QRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

517418:CTHA RS05240
gene id: 517418:CTHA_RS05240
uniprot id: B3QXU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS07325
gene id: 517418:CTHA_RS07325
uniprot id: B3QRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

517418:CTHA RS13780
gene id: 517418:CTHA_RS13780
uniprot id: B3QYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

517418:CTHA RS00580
gene id: 517418:CTHA_RS00580
uniprot id: B3QSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

517418:CTHA RS03360
gene id: 517418:CTHA_RS03360
uniprot id: B3QVR6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS01195
gene id: 517418:CTHA_RS01195
uniprot id: B3QTF4
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS09590
gene id: 517418:CTHA_RS09590
uniprot id: B3QTT9
names: Similarity
messages: Belongs to the P(II) protein family.

517418:CTHA RS11410
gene id: 517418:CTHA_RS11410
uniprot id: B3QVY3
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS05725
gene id: 517418:CTHA_RS05725
uniprot id: B3QYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

517418:CTHA RS11525
gene id: 517418:CTHA_RS11525
uniprot id: B3QW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS05630
gene id: 517418:CTHA_RS05630
uniprot id: B3QY15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

517418:CTHA RS02090
gene id: 517418:CTHA_RS02090
uniprot id: B3QUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS06215
gene id: 517418:CTHA_RS06215
uniprot id: B3QYM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

517418:CTHA RS07040
gene id: 517418:CTHA_RS07040
uniprot id: B3QZB7
names: Similarity
messages: Belongs to the aspartokinase family.

517418:CTHA RS06105
gene id: 517418:CTHA_RS06105
uniprot id: B3QYK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

517418:CTHA RS12125
gene id: 517418:CTHA_RS12125
uniprot id: B3QWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

517418:CTHA RS00165
gene id: 517418:CTHA_RS00165
uniprot id: B3QSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

517418:CTHA RS06695
gene id: 517418:CTHA_RS06695
uniprot id: B3QZ50
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

517418:CTHA RS12650
gene id: 517418:CTHA_RS12650
uniprot id: B3QX71
names: Similarity
messages: Belongs to the UPRTase family.

517418:CTHA RS07925
gene id: 517418:CTHA_RS07925
uniprot id: B3QS30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

517418:CTHA RS09600
gene id: 517418:CTHA_RS09600
uniprot id: B3QTU1
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

517418:CTHA RS13590
gene id: 517418:CTHA_RS13590
uniprot id: B3QY94
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

517418:CTHA RS03960
gene id: 517418:CTHA_RS03960
uniprot id: B3QWC0
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

517418:CTHA RS10970
gene id: 517418:CTHA_RS10970
uniprot id: B3QVE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

517418:CTHA RS05435
gene id: 517418:CTHA_RS05435
uniprot id: B3QXY0
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

517418:CTHA RS09435
gene id: 517418:CTHA_RS09435
uniprot id: B3QTR0
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS00855
gene id: 517418:CTHA_RS00855
uniprot id: B3QSZ2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

517418:CTHA RS09210
gene id: 517418:CTHA_RS09210
uniprot id: B3QTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

517418:CTHA RS10380
gene id: 517418:CTHA_RS10380
uniprot id: B3QUT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

517418:CTHA RS05750
gene id: 517418:CTHA_RS05750
uniprot id: B3QYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

517418:CTHA RS04550
gene id: 517418:CTHA_RS04550
uniprot id: B3QWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

517418:CTHA RS00505
gene id: 517418:CTHA_RS00505
uniprot id: B3QSH8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

517418:CTHA RS03865
gene id: 517418:CTHA_RS03865
uniprot id: B3QWA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

517418:CTHA RS12810
gene id: 517418:CTHA_RS12810
uniprot id: B3QXJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

517418:CTHA RS03225
gene id: 517418:CTHA_RS03225
uniprot id: B3QVP1
names: Similarity
messages: Belongs to the PucC family.

517418:CTHA RS03710
gene id: 517418:CTHA_RS03710
uniprot id: B3QW74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

517418:CTHA RS10650
gene id: 517418:CTHA_RS10650
uniprot id: B3QUY5
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS12395
gene id: 517418:CTHA_RS12395
uniprot id: B3QX23
names: Similarity
messages: Belongs to the UPF0162 family.

517418:CTHA RS03825
gene id: 517418:CTHA_RS03825
uniprot id: B3QW96
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

517418:CTHA RS13985
gene id: 517418:CTHA_RS13985
uniprot id: B3QYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS12600
gene id: 517418:CTHA_RS12600
uniprot id: B3QX61
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

517418:CTHA RS13340
gene id: 517418:CTHA_RS13340
uniprot id: B3QY45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS14205
gene id: 517418:CTHA_RS14205
uniprot id: B3QYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

517418:CTHA RS02720
gene id: 517418:CTHA_RS02720
uniprot id: B3QV48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

517418:CTHA RS03030
gene id: 517418:CTHA_RS03030
uniprot id: B3QVA8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

517418:CTHA RS03795
gene id: 517418:CTHA_RS03795
uniprot id: B3QW90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

517418:CTHA RS00970
gene id: 517418:CTHA_RS00970
uniprot id: B3QT15
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

517418:CTHA RS12815
gene id: 517418:CTHA_RS12815
uniprot id: B3QXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

517418:CTHA RS02130
gene id: 517418:CTHA_RS02130
uniprot id: B3QUI0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS00035
gene id: 517418:CTHA_RS00035
uniprot id: B3QRZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

517418:CTHA RS00960
gene id: 517418:CTHA_RS00960
uniprot id: B3QT13
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

517418:CTHA RS08535
gene id: 517418:CTHA_RS08535
uniprot id: B3QSP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

517418:CTHA RS11920
gene id: 517418:CTHA_RS11920
uniprot id: B3QWI1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

517418:CTHA RS04335
gene id: 517418:CTHA_RS04335
uniprot id: B3QWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

517418:CTHA RS00355
gene id: 517418:CTHA_RS00355
uniprot id: B3QSF1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

517418:CTHA RS06000
gene id: 517418:CTHA_RS06000
uniprot id: B3QYI6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

517418:CTHA RS14030
gene id: 517418:CTHA_RS14030
uniprot id: B3QYS1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

517418:CTHA RS02850
gene id: 517418:CTHA_RS02850
uniprot id: B3QV74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

517418:CTHA RS07630
gene id: 517418:CTHA_RS07630
uniprot id: B3QRX0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

517418:CTHA RS08880
gene id: 517418:CTHA_RS08880
uniprot id: B3QT54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

517418:CTHA RS07170
gene id: 517418:CTHA_RS07170
uniprot id: B3QZE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

517418:CTHA RS06310
gene id: 517418:CTHA_RS06310
uniprot id: B3QYX5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

517418:CTHA RS02785
gene id: 517418:CTHA_RS02785
uniprot id: B3QV61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS08390
gene id: 517418:CTHA_RS08390
uniprot id: B3QSL2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

517418:CTHA RS00320
gene id: 517418:CTHA_RS00320
uniprot id: B3QSE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

517418:CTHA RS10310
gene id: 517418:CTHA_RS10310
uniprot id: B3QUS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS08315
gene id: 517418:CTHA_RS08315
uniprot id: B3QSJ7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

517418:CTHA RS11700
gene id: 517418:CTHA_RS11700
uniprot id: B3QW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

517418:CTHA RS13195
gene id: 517418:CTHA_RS13195
uniprot id: B3QXR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

517418:CTHA RS06485
gene id: 517418:CTHA_RS06485
uniprot id: B3QZ09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

517418:CTHA RS04120
gene id: 517418:CTHA_RS04120
uniprot id: B3QWE4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

517418:CTHA RS00170
gene id: 517418:CTHA_RS00170
uniprot id: B3QSB4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

517418:CTHA RS02705
gene id: 517418:CTHA_RS02705
uniprot id: B3QV45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

517418:CTHA RS03645
gene id: 517418:CTHA_RS03645
uniprot id: B3QW62
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

517418:CTHA RS03005
gene id: 517418:CTHA_RS03005
uniprot id: B3QVA4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

517418:CTHA RS09755
gene id: 517418:CTHA_RS09755
uniprot id: B3QTX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

517418:CTHA RS04535
gene id: 517418:CTHA_RS04535
uniprot id: B3QWX3
names: Similarity
messages: Belongs to the threonine synthase family.

517418:CTHA RS03115
gene id: 517418:CTHA_RS03115
uniprot id: B3QVM1
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

517418:CTHA RS10470
gene id: 517418:CTHA_RS10470
uniprot id: B3QUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

517418:CTHA RS10510
gene id: 517418:CTHA_RS10510
uniprot id: B3QUW0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

517418:CTHA RS04385
gene id: 517418:CTHA_RS04385
uniprot id: B3QWU4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS05595
gene id: 517418:CTHA_RS05595
uniprot id: B3QY08
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

517418:CTHA RS09915
gene id: 517418:CTHA_RS09915
uniprot id: B3QUA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS02650
gene id: 517418:CTHA_RS02650
uniprot id: B3QV34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS02830
gene id: 517418:CTHA_RS02830
uniprot id: B3QV70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

517418:CTHA RS00975
gene id: 517418:CTHA_RS00975
uniprot id: B3QT16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

517418:CTHA RS02770
gene id: 517418:CTHA_RS02770
uniprot id: B3QV58
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

517418:CTHA RS10115
gene id: 517418:CTHA_RS10115
uniprot id: B3QUD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

517418:CTHA RS13915
gene id: 517418:CTHA_RS13915
uniprot id: B3QYP8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

517418:CTHA RS12495
gene id: 517418:CTHA_RS12495
uniprot id: B3QX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

517418:CTHA RS14875
gene id: 517418:CTHA_RS14875
uniprot id: B3QYV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

517418:CTHA RS11290
gene id: 517418:CTHA_RS11290
uniprot id: B3QVL3
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

517418:CTHA RS00055
gene id: 517418:CTHA_RS00055
uniprot id: B3QS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

517418:CTHA RS13650
gene id: 517418:CTHA_RS13650
uniprot id: B3QYA4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS13380
gene id: 517418:CTHA_RS13380
uniprot id: B3QY53
names: Similarity
messages: Belongs to the ferrochelatase family.

517418:CTHA RS00750
gene id: 517418:CTHA_RS00750
uniprot id: B3QSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

517418:CTHA RS09555
gene id: 517418:CTHA_RS09555
uniprot id: B3QTT3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

517418:CTHA RS14200
gene id: 517418:CTHA_RS14200
uniprot id: B3QYV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

517418:CTHA RS07110
gene id: 517418:CTHA_RS07110
uniprot id: B3QZD1
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

517418:CTHA RS03090
gene id: 517418:CTHA_RS03090
uniprot id: B3QVC0
names: Similarity
messages: Belongs to the hemerythrin family.

517418:CTHA RS02125
gene id: 517418:CTHA_RS02125
uniprot id: B3QUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

517418:CTHA RS14170
gene id: 517418:CTHA_RS14170
uniprot id: B3QYV0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

517418:CTHA RS01975
gene id: 517418:CTHA_RS01975
uniprot id: B3QU57
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS12345
gene id: 517418:CTHA_RS12345
uniprot id: B3QX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

517418:CTHA RS00185
gene id: 517418:CTHA_RS00185
uniprot id: B3QSB7
names: Similarity
messages: Belongs to the UPF0235 family.

517418:CTHA RS00440
gene id: 517418:CTHA_RS00440
uniprot id: B3QSG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

517418:CTHA RS07070
gene id: 517418:CTHA_RS07070
uniprot id: B3QZC3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

517418:CTHA RS06155
gene id: 517418:CTHA_RS06155
uniprot id: B3QYL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

517418:CTHA RS10675
gene id: 517418:CTHA_RS10675
uniprot id: B3QUY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS00015
gene id: 517418:CTHA_RS00015
uniprot id: B3QRZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

517418:CTHA RS00540
gene id: 517418:CTHA_RS00540
uniprot id: B3QSI5
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

517418:CTHA RS10540
gene id: 517418:CTHA_RS10540
uniprot id: B3QUW5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

517418:CTHA RS08060
gene id: 517418:CTHA_RS08060
uniprot id: B3QS55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

517418:CTHA RS00490
gene id: 517418:CTHA_RS00490
uniprot id: B3QSH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

517418:CTHA RS08685
gene id: 517418:CTHA_RS08685
uniprot id: B3QSR9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

517418:CTHA RS12040
gene id: 517418:CTHA_RS12040
uniprot id: B3QWK3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

517418:CTHA RS10300
gene id: 517418:CTHA_RS10300
uniprot id: B3QUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS05990
gene id: 517418:CTHA_RS05990
uniprot id: B3QYI4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

517418:CTHA RS01915
gene id: 517418:CTHA_RS01915
uniprot id: B3QU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

517418:CTHA RS05615
gene id: 517418:CTHA_RS05615
uniprot id: B3QY12
names: Similarity
messages: Belongs to the peptidase S13 family.

517418:CTHA RS00480
gene id: 517418:CTHA_RS00480
uniprot id: B3QSH4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

517418:CTHA RS08820
gene id: 517418:CTHA_RS08820
uniprot id: B3QT42
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

517418:CTHA RS06665
gene id: 517418:CTHA_RS06665
uniprot id: B3QZ44
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

517418:CTHA RS03770
gene id: 517418:CTHA_RS03770
uniprot id: B3QW86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

517418:CTHA RS14685
gene id: 517418:CTHA_RS14685
uniprot id: B3QUD4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

517418:CTHA RS06035
gene id: 517418:CTHA_RS06035
uniprot id: B3QYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

517418:CTHA RS10305
gene id: 517418:CTHA_RS10305
uniprot id: B3QUS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

517418:CTHA RS13725
gene id: 517418:CTHA_RS13725
uniprot id: B3QYB9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

517418:CTHA RS13815
gene id: 517418:CTHA_RS13815
uniprot id: B3QYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

517418:CTHA RS06020
gene id: 517418:CTHA_RS06020
uniprot id: B3QYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

517418:CTHA RS14285
gene id: 517418:CTHA_RS14285
uniprot id: B3QTL1
names: Similarity
messages: Belongs to the peptidase S24 family.

517418:CTHA RS06285
gene id: 517418:CTHA_RS06285
uniprot id: B3QYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

517418:CTHA RS03105
gene id: 517418:CTHA_RS03105
uniprot id: B3QVM0
names: Similarity
messages: Belongs to the peptidase S41A family.

517418:CTHA RS04190
gene id: 517418:CTHA_RS04190
uniprot id: B3QWQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

517418:CTHA RS11380
gene id: 517418:CTHA_RS11380
uniprot id: B3QVX7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

517418:CTHA RS06475
gene id: 517418:CTHA_RS06475
uniprot id: B3QZ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

517418:CTHA RS03465
gene id: 517418:CTHA_RS03465
uniprot id: B3QVT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

517418:CTHA RS02220
gene id: 517418:CTHA_RS02220
uniprot id: B3QUJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

517418:CTHA RS13930
gene id: 517418:CTHA_RS13930
uniprot id: B3QYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS08700
gene id: 517418:CTHA_RS08700
uniprot id: B3QSS2
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS14570
gene id: 517418:CTHA_RS14570
uniprot id: B3QRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

517418:CTHA RS04630
gene id: 517418:CTHA_RS04630
uniprot id: B3QWZ0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

517418:CTHA RS14150
gene id: 517418:CTHA_RS14150
uniprot id: B3QYU6
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

517418:CTHA RS05490
gene id: 517418:CTHA_RS05490
uniprot id: B3QXZ0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

517418:CTHA RS12560
gene id: 517418:CTHA_RS12560
uniprot id: B3QX54
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS11650
gene id: 517418:CTHA_RS11650
uniprot id: B3QW33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

517418:CTHA RS11430
gene id: 517418:CTHA_RS11430
uniprot id: B3QVY7
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS10105
gene id: 517418:CTHA_RS10105
uniprot id: B3QUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

517418:CTHA RS12995
gene id: 517418:CTHA_RS12995
uniprot id: B3QXM9
names: Similarity
messages: Belongs to the NadC/ModD family.

517418:CTHA RS13285
gene id: 517418:CTHA_RS13285
uniprot id: B3QY34
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

517418:CTHA RS09275
gene id: 517418:CTHA_RS09275
uniprot id: B3QTC8
names: Similarity
messages: Belongs to the CinA family.

517418:CTHA RS13865
gene id: 517418:CTHA_RS13865
uniprot id: B3QYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

517418:CTHA RS06675
gene id: 517418:CTHA_RS06675
uniprot id: B3QZ46
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

517418:CTHA RS04605
gene id: 517418:CTHA_RS04605
uniprot id: B3QWY6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

517418:CTHA RS04360
gene id: 517418:CTHA_RS04360
uniprot id: B3QWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

517418:CTHA RS00905
gene id: 517418:CTHA_RS00905
uniprot id: B3QT02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

517418:CTHA RS04155
gene id: 517418:CTHA_RS04155
uniprot id: B3QWF1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

517418:CTHA RS11875
gene id: 517418:CTHA_RS11875
uniprot id: B3QWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

517418:CTHA RS07635
gene id: 517418:CTHA_RS07635
uniprot id: B3QRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

517418:CTHA RS10280
gene id: 517418:CTHA_RS10280
uniprot id: B3QUG8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

517418:CTHA RS04510
gene id: 517418:CTHA_RS04510
uniprot id: B3QWW8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

517418:CTHA RS03440
gene id: 517418:CTHA_RS03440
uniprot id: B3QVT2
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS11040
gene id: 517418:CTHA_RS11040
uniprot id: B3QVG2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

517418:CTHA RS07095
gene id: 517418:CTHA_RS07095
uniprot id: B3QZC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

517418:CTHA RS07515
gene id: 517418:CTHA_RS07515
uniprot id: B3QRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

517418:CTHA RS02715
gene id: 517418:CTHA_RS02715
uniprot id: B3QV47
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

517418:CTHA RS02165
gene id: 517418:CTHA_RS02165
uniprot id: B3QUI7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

517418:CTHA RS04975
gene id: 517418:CTHA_RS04975
uniprot id: B3QXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS00890
gene id: 517418:CTHA_RS00890
uniprot id: B3QSZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

517418:CTHA RS08420
gene id: 517418:CTHA_RS08420
uniprot id: B3QSL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

517418:CTHA RS10455
gene id: 517418:CTHA_RS10455
uniprot id: B3QUV1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

517418:CTHA RS01860
gene id: 517418:CTHA_RS01860
uniprot id: B3QU33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS08890
gene id: 517418:CTHA_RS08890
uniprot id: B3QT56
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

517418:CTHA RS04880
gene id: 517418:CTHA_RS04880
uniprot id: B3QXC6
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

517418:CTHA RS00245
gene id: 517418:CTHA_RS00245
uniprot id: B3QSC9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

517418:CTHA RS13475
gene id: 517418:CTHA_RS13475
uniprot id: B3QY71
names: Similarity
messages: Belongs to the PspA/IM30 family.

517418:CTHA RS09735
gene id: 517418:CTHA_RS09735
uniprot id: B3QTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

517418:CTHA RS08485
gene id: 517418:CTHA_RS08485
uniprot id: B3QSN0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

517418:CTHA RS05360
gene id: 517418:CTHA_RS05360
uniprot id: B3QXW5
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

517418:CTHA RS11140
gene id: 517418:CTHA_RS11140
uniprot id: B3QVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

517418:CTHA RS01670
gene id: 517418:CTHA_RS01670
uniprot id: B3QTZ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

517418:CTHA RS13065
gene id: 517418:CTHA_RS13065
uniprot id: B3QXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

517418:CTHA RS10945
gene id: 517418:CTHA_RS10945
uniprot id: B3QVE3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

517418:CTHA RS13295
gene id: 517418:CTHA_RS13295
uniprot id: B3QY36
names: Similarity
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

517418:CTHA RS10040
gene id: 517418:CTHA_RS10040
uniprot id: B3QUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

517418:CTHA RS09345
gene id: 517418:CTHA_RS09345
uniprot id: B3QTP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

517418:CTHA RS00330
gene id: 517418:CTHA_RS00330
uniprot id: B3QSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

517418:CTHA RS09730
gene id: 517418:CTHA_RS09730
uniprot id: B3QTW8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

517418:CTHA RS06650
gene id: 517418:CTHA_RS06650
uniprot id: B3QZ41
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

517418:CTHA RS01850
gene id: 517418:CTHA_RS01850
uniprot id: B3QU31
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS07165
gene id: 517418:CTHA_RS07165
uniprot id: B3QZE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

517418:CTHA RS11075
gene id: 517418:CTHA_RS11075
uniprot id: B3QVG8
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS02500
gene id: 517418:CTHA_RS02500
uniprot id: B3QUQ2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

517418:CTHA RS15505
gene id: 517418:CTHA_RS15505
uniprot id: B3QRV8
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS07000
gene id: 517418:CTHA_RS07000
uniprot id: B3QZA9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

517418:CTHA RS07615
gene id: 517418:CTHA_RS07615
uniprot id: B3QRW7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

517418:CTHA RS01815
gene id: 517418:CTHA_RS01815
uniprot id: B3QU24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

517418:CTHA RS09585
gene id: 517418:CTHA_RS09585
uniprot id: B3QTT8
names: Similarity
messages: Belongs to the P(II) protein family.

517418:CTHA RS03545
gene id: 517418:CTHA_RS03545
uniprot id: B3QVV1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

517418:CTHA RS07020
gene id: 517418:CTHA_RS07020
uniprot id: B3QZB3
names: Similarity
messages: Belongs to the UPF0175 family.

517418:CTHA RS05710
gene id: 517418:CTHA_RS05710
uniprot id: B3QY31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

517418:CTHA RS05680
gene id: 517418:CTHA_RS05680
uniprot id: B3QY25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

517418:CTHA RS03420
gene id: 517418:CTHA_RS03420
uniprot id: B3QVS8
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS08080
gene id: 517418:CTHA_RS08080
uniprot id: B3QS58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

517418:CTHA RS02930
gene id: 517418:CTHA_RS02930
uniprot id: B3QV90
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

517418:CTHA RS03410
gene id: 517418:CTHA_RS03410
uniprot id: B3QVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

517418:CTHA RS13425
gene id: 517418:CTHA_RS13425
uniprot id: B3QY61
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS05760
gene id: 517418:CTHA_RS05760
uniprot id: B3QYE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

517418:CTHA RS05735
gene id: 517418:CTHA_RS05735
uniprot id: B3QYD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

517418:CTHA RS10630
gene id: 517418:CTHA_RS10630
uniprot id: B3QUY1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

517418:CTHA RS04645
gene id: 517418:CTHA_RS04645
uniprot id: B3QWZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

517418:CTHA RS04915
gene id: 517418:CTHA_RS04915
uniprot id: B3QXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

517418:CTHA RS12225
gene id: 517418:CTHA_RS12225
uniprot id: B3QWN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

517418:CTHA RS10445
gene id: 517418:CTHA_RS10445
uniprot id: B3QUU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

517418:CTHA RS10405
gene id: 517418:CTHA_RS10405
uniprot id: B3QUU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

517418:CTHA RS12355
gene id: 517418:CTHA_RS12355
uniprot id: B3QX15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

517418:CTHA RS02825
gene id: 517418:CTHA_RS02825
uniprot id: B3QV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

517418:CTHA RS08430
gene id: 517418:CTHA_RS08430
uniprot id: B3QSM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS00860
gene id: 517418:CTHA_RS00860
uniprot id: B3QSZ3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

517418:CTHA RS02645
gene id: 517418:CTHA_RS02645
uniprot id: B3QV33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

517418:CTHA RS12940
gene id: 517418:CTHA_RS12940
uniprot id: B3QXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

517418:CTHA RS13750
gene id: 517418:CTHA_RS13750
uniprot id: B3QYC4
names: Similarity
messages: Belongs to the UPF0047 family.

517418:CTHA RS14045
gene id: 517418:CTHA_RS14045
uniprot id: B3QYS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS08775
gene id: 517418:CTHA_RS08775
uniprot id: B3QT35
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

517418:CTHA RS08940
gene id: 517418:CTHA_RS08940
uniprot id: B3QT65
names: Similarity
messages: Belongs to the RuBisCO large chain family.

517418:CTHA RS12130
gene id: 517418:CTHA_RS12130
uniprot id: B3QWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

517418:CTHA RS07395
gene id: 517418:CTHA_RS07395
uniprot id: B3QRS5
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

517418:CTHA RS09410
gene id: 517418:CTHA_RS09410
uniprot id: B3QTQ5
names: Similarity
messages: Belongs to the Skp family.

517418:CTHA RS02305
gene id: 517418:CTHA_RS02305
uniprot id: B3QUL3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

517418:CTHA RS13460
gene id: 517418:CTHA_RS13460
uniprot id: B3QY68
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

517418:CTHA RS11885
gene id: 517418:CTHA_RS11885
uniprot id: B3QWH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

517418:CTHA RS09455
gene id: 517418:CTHA_RS09455
uniprot id: B3QTR4
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS07200
gene id: 517418:CTHA_RS07200
uniprot id: B3QZE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

517418:CTHA RS08540
gene id: 517418:CTHA_RS08540
uniprot id: B3QSP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

517418:CTHA RS07485
gene id: 517418:CTHA_RS07485
uniprot id: B3QRU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

517418:CTHA RS04850
gene id: 517418:CTHA_RS04850
uniprot id: B3QXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

517418:CTHA RS01775
gene id: 517418:CTHA_RS01775
uniprot id: B3QU17
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

517418:CTHA RS12880
gene id: 517418:CTHA_RS12880
uniprot id: B3QXK7
names: Similarity
messages: Belongs to the PGI/PMI family.

517418:CTHA RS13880
gene id: 517418:CTHA_RS13880
uniprot id: B3QYP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

517418:CTHA RS05665
gene id: 517418:CTHA_RS05665
uniprot id: B3QY22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

517418:CTHA RS07945
gene id: 517418:CTHA_RS07945
uniprot id: B3QS34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

517418:CTHA RS07875
gene id: 517418:CTHA_RS07875
uniprot id: B3QS24
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

517418:CTHA RS10245
gene id: 517418:CTHA_RS10245
uniprot id: B3QUG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS03650
gene id: 517418:CTHA_RS03650
uniprot id: B3QW63
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

517418:CTHA RS01155
gene id: 517418:CTHA_RS01155
uniprot id: B3QTE6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

517418:CTHA RS12755
gene id: 517418:CTHA_RS12755
uniprot id: B3QX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

517418:CTHA RS05700
gene id: 517418:CTHA_RS05700
uniprot id: B3QY29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

517418:CTHA RS06275
gene id: 517418:CTHA_RS06275
uniprot id: B3QYW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

517418:CTHA RS12435
gene id: 517418:CTHA_RS12435
uniprot id: B3QX31
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

517418:CTHA RS02085
gene id: 517418:CTHA_RS02085
uniprot id: B3QUH1
names: Similarity
messages: Belongs to the P(II) protein family.

517418:CTHA RS11420
gene id: 517418:CTHA_RS11420
uniprot id: B3QVY5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

517418:CTHA RS06160
gene id: 517418:CTHA_RS06160
uniprot id: B3QYL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

517418:CTHA RS01675
gene id: 517418:CTHA_RS01675
uniprot id: B3QTZ9
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS11695
gene id: 517418:CTHA_RS11695
uniprot id: B3QW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

517418:CTHA RS12985
gene id: 517418:CTHA_RS12985
uniprot id: B3QXM7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

517418:CTHA RS09200
gene id: 517418:CTHA_RS09200
uniprot id: B3QTB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

517418:CTHA RS06660
gene id: 517418:CTHA_RS06660
uniprot id: B3QZ43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS05590
gene id: 517418:CTHA_RS05590
uniprot id: B3QY07
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

517418:CTHA RS05960
gene id: 517418:CTHA_RS05960
uniprot id: B3QYH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

517418:CTHA RS06940
gene id: 517418:CTHA_RS06940
uniprot id: B3QZ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

517418:CTHA RS01085
gene id: 517418:CTHA_RS01085
uniprot id: B3QTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

517418:CTHA RS00205
gene id: 517418:CTHA_RS00205
uniprot id: B3QSC2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

517418:CTHA RS02710
gene id: 517418:CTHA_RS02710
uniprot id: B3QV46
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

517418:CTHA RS11895
gene id: 517418:CTHA_RS11895
uniprot id: B3QWH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

517418:CTHA RS05100
gene id: 517418:CTHA_RS05100
uniprot id: B3QXG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS05775
gene id: 517418:CTHA_RS05775
uniprot id: B3QYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

517418:CTHA RS04025
gene id: 517418:CTHA_RS04025
uniprot id: B3QWC5
names: Similarity
messages: Belongs to the GARS family.

517418:CTHA RS06435
gene id: 517418:CTHA_RS06435
uniprot id: B3QYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

517418:CTHA RS07990
gene id: 517418:CTHA_RS07990
uniprot id: B3QS43
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

517418:CTHA RS12950
gene id: 517418:CTHA_RS12950
uniprot id: B3QXM1
names: Similarity
messages: Belongs to the FemABX family.

517418:CTHA RS10255
gene id: 517418:CTHA_RS10255
uniprot id: B3QUG4
names: Similarity
messages: Belongs to the pyruvate kinase family.

517418:CTHA RS03365
gene id: 517418:CTHA_RS03365
uniprot id: B3QVR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

517418:CTHA RS08215
gene id: 517418:CTHA_RS08215
uniprot id: B3QS82
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

517418:CTHA RS08680
gene id: 517418:CTHA_RS08680
uniprot id: B3QSR8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

517418:CTHA RS06140
gene id: 517418:CTHA_RS06140
uniprot id: B3QYL0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

517418:CTHA RS08770
gene id: 517418:CTHA_RS08770
uniprot id: B3QT34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

517418:CTHA RS11915
gene id: 517418:CTHA_RS11915
uniprot id: B3QWI0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

517418:CTHA RS03275
gene id: 517418:CTHA_RS03275
uniprot id: B3QVQ0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

517418:CTHA RS05430
gene id: 517418:CTHA_RS05430
uniprot id: B3QXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

517418:CTHA RS07400
gene id: 517418:CTHA_RS07400
uniprot id: B3QRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

517418:CTHA RS06360
gene id: 517418:CTHA_RS06360
uniprot id: B3QYY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

517418:CTHA RS01300
gene id: 517418:CTHA_RS01300
uniprot id: B3QTH5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

517418:CTHA RS10815
gene id: 517418:CTHA_RS10815
uniprot id: B3QV16
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS08230
gene id: 517418:CTHA_RS08230
uniprot id: B3QS85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

517418:CTHA RS13955
gene id: 517418:CTHA_RS13955
uniprot id: B3QYQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

517418:CTHA RS03820
gene id: 517418:CTHA_RS03820
uniprot id: B3QW95
names: Similarity
messages: Belongs to the universal stress protein A family.

517418:CTHA RS10400
gene id: 517418:CTHA_RS10400
uniprot id: B3QUU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS01570
gene id: 517418:CTHA_RS01570
uniprot id: B3QTM9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

517418:CTHA RS07550
gene id: 517418:CTHA_RS07550
uniprot id: B3QRV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS05940
gene id: 517418:CTHA_RS05940
uniprot id: B3QYH5
names: Similarity
messages: Belongs to the BshC family.

517418:CTHA RS05570
gene id: 517418:CTHA_RS05570
uniprot id: B3QY03
names: Similarity
messages: Belongs to the hemerythrin family.

517418:CTHA RS04520
gene id: 517418:CTHA_RS04520
uniprot id: B3QWX0
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS00950
gene id: 517418:CTHA_RS00950
uniprot id: B3QT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

517418:CTHA RS03045
gene id: 517418:CTHA_RS03045
uniprot id: B3QVB1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

517418:CTHA RS07785
gene id: 517418:CTHA_RS07785
uniprot id: B3QS08
names: Similarity
messages: Belongs to the arsA ATPase family.

517418:CTHA RS13805
gene id: 517418:CTHA_RS13805
uniprot id: B3QYM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

517418:CTHA RS00785
gene id: 517418:CTHA_RS00785
uniprot id: B3QSX9
names: Subcellular Location Annotation
messages: Cytoplasm

517418:CTHA RS00940
gene id: 517418:CTHA_RS00940
uniprot id: B3QT09
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

517418:CTHA RS02350
gene id: 517418:CTHA_RS02350
uniprot id: B3QUM1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

517418:CTHA RS13310
gene id: 517418:CTHA_RS13310
uniprot id: B3QY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

517418:CTHA RS03725
gene id: 517418:CTHA_RS03725
uniprot id: B3QW77
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

517418:CTHA RS05740
gene id: 517418:CTHA_RS05740
uniprot id: B3QYD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

517418:CTHA RS04330
gene id: 517418:CTHA_RS04330
uniprot id: B3QWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

517418:CTHA RS14235
gene id: 517418:CTHA_RS14235
uniprot id: B3QSA0
names: Subcellular Location Annotation
messages: Cell inner membrane

517418:CTHA RS02075
gene id: 517418:CTHA_RS02075
uniprot id: B3QU77
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

517418:CTHA RS08525
gene id: 517418:CTHA_RS08525
uniprot id: B3QSN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

517418:CTHA RS03685
gene id: 517418:CTHA_RS03685
uniprot id: B3QW69
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

517418:CTHA RS12025
gene id: 517418:CTHA_RS12025
uniprot id: B3QWK0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

517418:CTHA RS09855
gene id: 517418:CTHA_RS09855
uniprot id: B3QU90
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

517418:CTHA RS13995
gene id: 517418:CTHA_RS13995
uniprot id: B3QYR4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

517418:CTHA RS05805
gene id: 517418:CTHA_RS05805
uniprot id: B3QYF0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

517418:CTHA RS02685
gene id: 517418:CTHA_RS02685
uniprot id: B3QV41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

517418:CTHA RS01210
gene id: 517418:CTHA_RS01210
uniprot id: B3QTF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

517418:CTHA RS07120
gene id: 517418:CTHA_RS07120
uniprot id: B3QZD3
names: Similarity
messages: Belongs to the acylphosphatase family.

517418:CTHA RS13840
gene id: 517418:CTHA_RS13840
uniprot id: B3QYN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

517418:CTHA RS00935
gene id: 517418:CTHA_RS00935
uniprot id: B3QT08
names: Similarity
messages: Belongs to the sigma-54 factor family.

517418:CTHA RS05535
gene id: 517418:CTHA_RS05535
uniprot id: B3QXZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

517418:CTHA RS10880
gene id: 517418:CTHA_RS10880
uniprot id: B3QVD0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

517418:CTHA RS05355
gene id: 517418:CTHA_RS05355
uniprot id: B3QXW4
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

517418:CTHA RS12770
gene id: 517418:CTHA_RS12770
uniprot id: B3QXI7
names: Subcellular Location Annotation
messages: Mitochondrion

517418:CTHA RS03035
gene id: 517418:CTHA_RS03035
uniprot id: B3QVA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

517418:CTHA RS10030
gene id: 517418:CTHA_RS10030
uniprot id: B3QUC3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

517418:CTHA RS02915
gene id: 517418:CTHA_RS02915
uniprot id: B3QV87
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

517418:CTHA RS05005
gene id: 517418:CTHA_RS05005
uniprot id: B3QXF0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

517418:CTHA RS07420
gene id: 517418:CTHA_RS07420
uniprot id: B3QRT0
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS05370
gene id: 517418:CTHA_RS05370
uniprot id: B3QXW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

517418:CTHA RS07520
gene id: 517418:CTHA_RS07520
uniprot id: B3QRU8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

517418:CTHA RS02600
gene id: 517418:CTHA_RS02600
uniprot id: B3QV24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

517418:CTHA RS02980
gene id: 517418:CTHA_RS02980
uniprot id: B3QV99
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS00795
gene id: 517418:CTHA_RS00795
uniprot id: B3QSY1
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS10435
gene id: 517418:CTHA_RS10435
uniprot id: B3QUU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

517418:CTHA RS05770
gene id: 517418:CTHA_RS05770
uniprot id: B3QYE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

517418:CTHA RS09195
gene id: 517418:CTHA_RS09195
uniprot id: B3QTB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

517418:CTHA RS00295
gene id: 517418:CTHA_RS00295
uniprot id: B3QSD9
names: Function
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

517418:CTHA RS06690
gene id: 517418:CTHA_RS06690
uniprot id: B3QZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

517418:CTHA RS01110
gene id: 517418:CTHA_RS01110
uniprot id: B3QTD7
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS02455
gene id: 517418:CTHA_RS02455
uniprot id: B3QUP4
names: Similarity
messages: Belongs to the peptidase S66 family.

517418:CTHA RS14390
gene id: 517418:CTHA_RS14390
uniprot id: B3QVS4
names: Subcellular Location Annotation
messages: Cytoplasm

517418:CTHA RS01230
gene id: 517418:CTHA_RS01230
uniprot id: B3QTG1
names: Similarity
messages: Belongs to the peptidase S8 family.

517418:CTHA RS05080
gene id: 517418:CTHA_RS05080
uniprot id: B3QXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

517418:CTHA RS01880
gene id: 517418:CTHA_RS01880
uniprot id: B3QU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

517418:CTHA RS06730
gene id: 517418:CTHA_RS06730
uniprot id: B3QZ57
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

517418:CTHA RS04080
gene id: 517418:CTHA_RS04080
uniprot id: B3QWD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

517418:CTHA RS14790
gene id: 517418:CTHA_RS14790
uniprot id: B3QWP3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

517418:CTHA RS04375
gene id: 517418:CTHA_RS04375
uniprot id: B3QWU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS08705
gene id: 517418:CTHA_RS08705
uniprot id: B3QSS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

517418:CTHA RS12900
gene id: 517418:CTHA_RS12900
uniprot id: B3QXL1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

517418:CTHA RS07965
gene id: 517418:CTHA_RS07965
uniprot id: B3QS38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

517418:CTHA RS09425
gene id: 517418:CTHA_RS09425
uniprot id: B3QTQ8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

517418:CTHA RS06935
gene id: 517418:CTHA_RS06935
uniprot id: B3QZ96
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

517418:CTHA RS12060
gene id: 517418:CTHA_RS12060
uniprot id: B3QWK7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

517418:CTHA RS04685
gene id: 517418:CTHA_RS04685
uniprot id: B3QX01
names: Subcellular Location Annotation
messages: Membrane

517418:CTHA RS09550
gene id: 517418:CTHA_RS09550
uniprot id: B3QTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

517418:CTHA RS02815
gene id: 517418:CTHA_RS02815
uniprot id: B3QV67
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

517418:CTHA RS08480
gene id: 517418:CTHA_RS08480
uniprot id: B3QSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

517418:CTHA RS05645
gene id: 517418:CTHA_RS05645
uniprot id: B3QY18
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS02545
gene id: 517418:CTHA_RS02545
uniprot id: B3QUR1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

517418:CTHA RS06655
gene id: 517418:CTHA_RS06655
uniprot id: B3QZ42
names: Similarity
messages: Belongs to the peptidase A31 family.

517418:CTHA RS03480
gene id: 517418:CTHA_RS03480
uniprot id: B3QVT9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

517418:CTHA RS01565
gene id: 517418:CTHA_RS01565
uniprot id: B3QTM8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

517418:CTHA RS02605
gene id: 517418:CTHA_RS02605
uniprot id: B3QV25
names: Similarity
messages: Belongs to the ComB family.

517418:CTHA RS00030
gene id: 517418:CTHA_RS00030
uniprot id: B3QRZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

517418:CTHA RS11310
gene id: 517418:CTHA_RS11310
uniprot id: B3QVL7
names: Similarity
messages: Belongs to the glutamate synthase family.

517418:CTHA RS13795
gene id: 517418:CTHA_RS13795
uniprot id: B3QYM6
names: Similarity
messages: Belongs to the ParB family.

517418:CTHA RS06710
gene id: 517418:CTHA_RS06710
uniprot id: B3QZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

517418:CTHA RS12775
gene id: 517418:CTHA_RS12775
uniprot id: B3QXI8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

517418:CTHA RS04400
gene id: 517418:CTHA_RS04400
uniprot id: B3QWU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

517418:CTHA RS09375
gene id: 517418:CTHA_RS09375
uniprot id: B3QTP8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

517418:CTHA RS09190
gene id: 517418:CTHA_RS09190
uniprot id: B3QTB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

517418:CTHA RS11575
gene id: 517418:CTHA_RS11575
uniprot id: B3QW17
names: Similarity
messages: Belongs to the CobH/CbiC family.

517418:CTHA RS06810
gene id: 517418:CTHA_RS06810
uniprot id: B3QZ71
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

517418:CTHA RS06600
gene id: 517418:CTHA_RS06600
uniprot id: B3QZ31
names: Similarity
messages: Belongs to the AlaDH/PNT family.

517418:CTHA RS10855
gene id: 517418:CTHA_RS10855
uniprot id: B3QVC5
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.