51337:Sdhb
gene id: 51337:Sdhb
uniprot id: A0A8C5L144
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

51337:Hpse2
gene id: 51337:Hpse2
uniprot id: A0A8C5KT34
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

51337:Ppm1g
gene id: 51337:Ppm1g
uniprot id: A0A8C5KYT5
names: Similarity
messages: Belongs to the PP2C family.

51337:LOC101601264
gene id: 51337:LOC101601264
uniprot id: A0A8C5KKS2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

51337:Snx11
gene id: 51337:Snx11
uniprot id: A0A8C5NVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

51337:LOC101616527
gene id: 51337:LOC101616527
uniprot id: A0A8C5L3E2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

51337:Add3
gene id: 51337:Add3
uniprot id: A0A8C5LG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Membrane
messages: cytoskeleton

51337:LOC101607210
gene id: 51337:LOC101607210
uniprot id: A0A8C5KBE9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

51337:Mpc2
gene id: 51337:Mpc2
uniprot id: A0A8C5LHZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Fam118b
gene id: 51337:Fam118b
uniprot id: A0A8C5P2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

51337:Napb
gene id: 51337:Napb
uniprot id: A0A8C5K872
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

51337:LOC101617608
gene id: 51337:LOC101617608
uniprot id: A0A8C5K3T2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Ormdl1
gene id: 51337:Ormdl1
uniprot id: A0A8C5KLY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

51337:Actr1a
gene id: 51337:Actr1a
uniprot id: A0A8C5NY06
names: Similarity
messages: Belongs to the actin family.

51337:Srp68
gene id: 51337:Srp68
uniprot id: A0A8C5K328
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

51337:LOC101604442
gene id: 51337:LOC101604442
uniprot id: A0A8C5KBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

51337:Ttll1
gene id: 51337:Ttll1
uniprot id: A0A8C5K181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

51337:Tmem175
gene id: 51337:Tmem175
uniprot id: A0A8C5P2R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

51337:Tekt5
gene id: 51337:Tekt5
uniprot id: A0A8C5LAX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

51337:Grem2
gene id: 51337:Grem2
uniprot id: A0A8C5NX14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:C13H5orf22
gene id: 51337:C13H5orf22
uniprot id: A0A8C5K8N6
names: Similarity
messages: Belongs to the UPF0489 family.

51337:Supt4h1
gene id: 51337:Supt4h1
uniprot id: A0A8C5KAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

51337:LOC101605234
gene id: 51337:LOC101605234
uniprot id: A0A8C5L6J9
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

51337:Chst12
gene id: 51337:Chst12
uniprot id: A0A8C5KEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Adgrb3
gene id: 51337:Adgrb3
uniprot id: A0A8C5K917
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Lrp1
gene id: 51337:Lrp1
uniprot id: A0A8C5P5K6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Yipf6
gene id: 51337:Yipf6
uniprot id: A0A8C5KM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

51337:Pycr1
gene id: 51337:Pycr1
uniprot id: A0A8C5KAI2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

51337:LOC101606718
gene id: 51337:LOC101606718
uniprot id: A0A8C5KI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Mks1
gene id: 51337:Mks1
uniprot id: A0A8C5LDL6
names: Subcellular Location Annotation
messages: cilium basal body

51337:Lix1
gene id: 51337:Lix1
uniprot id: A0A8C5LF98
names: Similarity
messages: Belongs to the LIX1 family.

51337:Cd53
gene id: 51337:Cd53
uniprot id: A0A8C5LD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Ube2d2
gene id: 51337:Ube2d2
uniprot id: A0A8C5NZH7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Phyhipl
gene id: 51337:Phyhipl
uniprot id: A0A8C5JYC6
names: Similarity
messages: Belongs to the PHYHIP family.

51337:Hdac11
gene id: 51337:Hdac11
uniprot id: A0A8C5KGJ1
names: Subcellular Location Annotation
messages: Nucleus

51337:Nr4a2
gene id: 51337:Nr4a2
uniprot id: A0A8C5KXI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

51337:Fut8
gene id: 51337:Fut8
uniprot id: A0A8C5LB24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

51337:Cdpf1
gene id: 51337:Cdpf1
uniprot id: A0A8C5L5B2
names: Similarity
messages: Belongs to the CDPF1 family.

51337:Pla2g2a
gene id: 51337:Pla2g2a
uniprot id: A0A8C5P384
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

51337:S100a11
gene id: 51337:S100a11
uniprot id: A0A8C5KRA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

51337:Pdhx
gene id: 51337:Pdhx
uniprot id: A0A8C5K1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

51337:Prf1
gene id: 51337:Prf1
uniprot id: A0A8C5NVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

51337:Oplah
gene id: 51337:Oplah
uniprot id: A0A8C5LJU2
names: Similarity
messages: Belongs to the oxoprolinase family.

51337:Il2
gene id: 51337:Il2
uniprot id: A0A8C5LB05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-2 family.
messages: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
messages: Secreted

51337:Rorb
gene id: 51337:Rorb
uniprot id: A0A8C5KI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

51337:Gatb
gene id: 51337:Gatb
uniprot id: A0A8C5KUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

51337:Dlst
gene id: 51337:Dlst
uniprot id: A0A8C5KWU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

51337:Tssk6
gene id: 51337:Tssk6
uniprot id: A0A8C5K1F5
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:LOC101616503
gene id: 51337:LOC101616503
uniprot id: A0A8C5KPE3
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

51337:Gjb3
gene id: 51337:Gjb3
uniprot id: A0A8C5K4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Sft2d1
gene id: 51337:Sft2d1
uniprot id: A0A8C5LH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

51337:Mtm1
gene id: 51337:Mtm1
uniprot id: A0A8C5L834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

51337:Pdgfa
gene id: 51337:Pdgfa
uniprot id: A0A8C5KSQ1
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

51337:Slc30a8
gene id: 51337:Slc30a8
uniprot id: A0A8C5LBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cell membrane
messages: Membrane
messages: secretory vesicle membrane

51337:Hpgd
gene id: 51337:Hpgd
uniprot id: A0A8C5NYR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Tmem11
gene id: 51337:Tmem11
uniprot id: A0A8C5L6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

51337:Gpt
gene id: 51337:Gpt
uniprot id: A0A8C5K666
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

51337:Sema7a
gene id: 51337:Sema7a
uniprot id: A0A8C5K7H7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Nrn1
gene id: 51337:Nrn1
uniprot id: A0A8C5JY89
names: Similarity
messages: Belongs to the neuritin family.

51337:Slc6a12
gene id: 51337:Slc6a12
uniprot id: A0A8C5L2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
messages: Interacts with LIN7C.
messages: Membrane
messages: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.

51337:Ikbke
gene id: 51337:Ikbke
uniprot id: A0A8C5KGT7
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Cartpt
gene id: 51337:Cartpt
uniprot id: A0A8C5JYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

51337:Zadh2
gene id: 51337:Zadh2
uniprot id: A0A8C5KGI1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

51337:Sgce
gene id: 51337:Sgce
uniprot id: A0A8C5KXC5
uniprot id: A0A8C5KYS6
uniprot id: A0A8C5P197
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: cytoskeleton
messages: dendrite
messages: sarcolemma

51337:Ms4a5
gene id: 51337:Ms4a5
uniprot id: A0A8C5KSJ4
names: Similarity
messages: Belongs to the MS4A family.

51337:Abcg1
gene id: 51337:Abcg1
uniprot id: A0A8C5K849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

51337:Nlgn3
gene id: 51337:Nlgn3
uniprot id: A0A8C5LBP9
uniprot id: A0A8C5LH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

51337:Ucp3
gene id: 51337:Ucp3
uniprot id: A0A8C5P069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Tmem94
gene id: 51337:Tmem94
uniprot id: A0A8C5NW83
names: Subcellular Location Annotation
messages: Membrane

51337:Fancc
gene id: 51337:Fancc
uniprot id: A0A8C5K1E8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

51337:Thg1l
gene id: 51337:Thg1l
uniprot id: A0A8C5LD53
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

51337:Grk7
gene id: 51337:Grk7
uniprot id: A0A8C5LIV9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

51337:Mrpl33
gene id: 51337:Mrpl33
uniprot id: A0A8C5L815
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

51337:Sf3b6
gene id: 51337:Sf3b6
uniprot id: A0A8C5P420
names: Subcellular Location Annotation
messages: Nucleus

51337:Capn15
gene id: 51337:Capn15
uniprot id: A0A8C5LCM1
names: Similarity
messages: Belongs to the peptidase C2 family.

51337:LOC101596962
gene id: 51337:LOC101596962
uniprot id: A0A8C5NXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

51337:Syne3
gene id: 51337:Syne3
uniprot id: A0A8C5KYB2
names: Similarity
messages: Belongs to the nesprin family.

51337:Irf4
gene id: 51337:Irf4
uniprot id: A0A8C5L6N7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Slc6a2
gene id: 51337:Slc6a2
uniprot id: A0A8C5P4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:Lipa
gene id: 51337:Lipa
uniprot id: A0A8C5KNJ8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

51337:Ccz1
gene id: 51337:Ccz1
uniprot id: A0A8C5K2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

51337:Hsd3b7
gene id: 51337:Hsd3b7
uniprot id: A0A8C5NVJ1
names: Similarity
messages: Belongs to the 3-beta-HSD family.

51337:Fuca2
gene id: 51337:Fuca2
uniprot id: A0A8C5KTJ9
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

51337:LOC101600419
gene id: 51337:LOC101600419
uniprot id: A0A8C5KGQ3
names: Similarity
messages: Belongs to the SEN15 family.

51337:Dock6
gene id: 51337:Dock6
uniprot id: A0A8C5L0K0
names: Similarity
messages: Belongs to the DOCK family.

51337:Tmco3
gene id: 51337:Tmco3
uniprot id: A0A8C5P3U7
names: Subcellular Location Annotation
messages: Membrane

51337:Slc25a14
gene id: 51337:Slc25a14
uniprot id: A0A8C5KSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Tmem53
gene id: 51337:Tmem53
uniprot id: A0A8C5L357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

51337:LOC101612483
gene id: 51337:LOC101612483
uniprot id: A0A8C5KF06
names: Similarity
messages: Belongs to the aldo/keto reductase family.

51337:Brms1l
gene id: 51337:Brms1l
uniprot id: A0A8C5KFW1
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101614029
gene id: 51337:LOC101614029
uniprot id: A0A8C5NW19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

51337:LOC101616426
gene id: 51337:LOC101616426
uniprot id: A0A8C5NXA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
messages: Homotetramer. Interacts with APAF1. May interact with CASP1.
messages: Membrane
messages: cytoskeleton

51337:Elf3
gene id: 51337:Elf3
uniprot id: A0A8C5LCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Prkacb
gene id: 51337:Prkacb
uniprot id: A0A8C5NXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Cell membrane
messages: Membrane

51337:Ddx5
gene id: 51337:Ddx5
uniprot id: A0A8C5KXV9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

51337:Was
gene id: 51337:Was
uniprot id: A0A8C5KFV8
names: Subcellular Location Annotation
messages: Nucleus

51337:Pcsk2
gene id: 51337:Pcsk2
uniprot id: A0A8C5NZN7
names: Similarity
messages: Belongs to the peptidase S8 family.

51337:Slc16a11
gene id: 51337:Slc16a11
uniprot id: A0A8C5KP12
names: Subcellular Location Annotation
messages: Membrane

51337:Leprotl1
gene id: 51337:Leprotl1
uniprot id: A0A8C5KWZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

51337:Tie1
gene id: 51337:Tie1
uniprot id: A0A8C5LAI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Scrn2
gene id: 51337:Scrn2
uniprot id: A0A8C5LKF1
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

51337:Erg28
gene id: 51337:Erg28
uniprot id: A0A8C5P0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Rps2
gene id: 51337:Rps2
uniprot id: A0A8C5NXD9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

51337:Map2k2
gene id: 51337:Map2k2
uniprot id: A0A8C5KVI6
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Arvcf
gene id: 51337:Arvcf
uniprot id: A0A8C5KRG3
names: Similarity
messages: Belongs to the beta-catenin family.

51337:Maf1
gene id: 51337:Maf1
uniprot id: A0A8C5L5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

51337:Fgf18
gene id: 51337:Fgf18
uniprot id: A0A8C5KX32
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Cenpm
gene id: 51337:Cenpm
uniprot id: A0A8C5P312
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101596178
gene id: 51337:LOC101596178
uniprot id: A0A8C5KFG2
names: Subcellular Location Annotation
messages: Membrane

51337:Ndufa11
gene id: 51337:Ndufa11
uniprot id: A0A8C5P510
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Elapor1
gene id: 51337:Elapor1
uniprot id: A0A8C5L7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

51337:Rpl36al
gene id: 51337:Rpl36al
uniprot id: A0A8C5KIR3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

51337:Eef2k
gene id: 51337:Eef2k
uniprot id: A0A8C5KYR6
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

51337:Gart
gene id: 51337:Gart
uniprot id: A0A8C5LEF4
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

51337:St3gal4
gene id: 51337:St3gal4
uniprot id: A0A8C5L793
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Epha2
gene id: 51337:Epha2
uniprot id: A0A8C5NVZ2
names: Subcellular Location Annotation
messages: Membrane

51337:Serpinc1
gene id: 51337:Serpinc1
uniprot id: A0A8C5KNC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

51337:Eif1ad
gene id: 51337:Eif1ad
uniprot id: A0A8C5L6G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF1AD family.
messages: Interacts with GAPDH and STAT1.
messages: Plays a role into cellular response to oxidative stress. Decreases cell proliferation.

51337:Slc16a6
gene id: 51337:Slc16a6
uniprot id: A0A8C5L4D4
names: Subcellular Location Annotation
messages: Membrane

51337:Erh
gene id: 51337:Erh
uniprot id: A0A8C5LE95
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

51337:LOC101608200
gene id: 51337:LOC101608200
uniprot id: A0A8C5KVW2
uniprot id: A0A8C5P267
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Perikaryon
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

51337:Foxi1
gene id: 51337:Foxi1
uniprot id: A0A8C5LE63
names: Subcellular Location Annotation
messages: Nucleus

51337:Arglu1
gene id: 51337:Arglu1
uniprot id: A0A8C5K226
names: Similarity
messages: Belongs to the UPF0430 family.

51337:Nop10
gene id: 51337:Nop10
uniprot id: A0A8C5KUR0
names: Similarity
messages: Belongs to the NOP10 family.

51337:KEG00 p06
gene id: 51337:KEG00_p06
uniprot id: Q710S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM186. Interacts with TMEM242.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

51337:Hoxc10
gene id: 51337:Hoxc10
uniprot id: A0A8C5KBH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

51337:Ptdss1
gene id: 51337:Ptdss1
uniprot id: A0A8C5L959
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:C1H9orf78
gene id: 51337:C1H9orf78
uniprot id: A0A8C5L447
names: Similarity
messages: Belongs to the TLS1 family.

51337:Lhx9
gene id: 51337:Lhx9
uniprot id: A0A8C5JYQ6
uniprot id: A0A8C5K0E6
uniprot id: A0A8C5K1E1
names: Subcellular Location Annotation
messages: Nucleus

51337:Rngtt
gene id: 51337:Rngtt
uniprot id: A0A8C5L6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

51337:Tlx2
gene id: 51337:Tlx2
uniprot id: A0A8C5L9L9
names: Subcellular Location Annotation
messages: Nucleus

51337:Gpc2
gene id: 51337:Gpc2
uniprot id: A0A8C5NUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

51337:Hpdl
gene id: 51337:Hpdl
uniprot id: A0A8C5KLL6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

51337:LOC101597724
gene id: 51337:LOC101597724
uniprot id: A0A8C5LEM8
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Gabra6
gene id: 51337:Gabra6
uniprot id: A0A8C5K5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Kiss1r
gene id: 51337:Kiss1r
uniprot id: A0A8C5KR74
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101617478
gene id: 51337:LOC101617478
uniprot id: A0A8C5KJI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Rps27a
gene id: 51337:Rps27a
uniprot id: A0A8C5KX43
names: Function
names: Similarity
names: Subunit
messages: Component of the 40S subunit of the ribosome.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

51337:Slc7a10
gene id: 51337:Slc7a10
uniprot id: A0A8C5K1H3
names: Subcellular Location Annotation
messages: Membrane

51337:Cldn7
gene id: 51337:Cldn7
uniprot id: A0A8C5LH83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Atxn1l
gene id: 51337:Atxn1l
uniprot id: A0A8C5JYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

51337:Trim10
gene id: 51337:Trim10
uniprot id: A0A8C5JU89
names: Similarity
names: Subunit
messages: Belongs to the TRIM/RBCC family.
messages: Interacts with IFNAR1; this interaction prevents association of IFNAR1 with TYK2.

51337:Ndufa5
gene id: 51337:Ndufa5
uniprot id: A0A8C5NWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Spcs2
gene id: 51337:Spcs2
uniprot id: A0A8C5L9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Tm4sf4
gene id: 51337:Tm4sf4
uniprot id: A0A8C5K1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

51337:Slc24a3
gene id: 51337:Slc24a3
uniprot id: A0A8C5KQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

51337:Serping1
gene id: 51337:Serping1
uniprot id: A0A8C5KXJ7
names: Similarity
messages: Belongs to the serpin family.

51337:Mboat4
gene id: 51337:Mboat4
uniprot id: A0A8C5KZY1
names: Subcellular Location Annotation
messages: Membrane

51337:Il12rb2
gene id: 51337:Il12rb2
uniprot id: A0A8C5L5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

51337:KEG00 p07
gene id: 51337:KEG00_p07
uniprot id: Q710S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

51337:Vasn
gene id: 51337:Vasn
uniprot id: A0A8C5JZY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Casq2
gene id: 51337:Casq2
uniprot id: A0A8C5L5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

51337:LOC101594463
gene id: 51337:LOC101594463
uniprot id: A0A8C5KCI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:LOC101605680
gene id: 51337:LOC101605680
uniprot id: A0A8C5KAI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Gng8
gene id: 51337:Gng8
uniprot id: A0A8C5KXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:Tspan4
gene id: 51337:Tspan4
uniprot id: A0A8C5LH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Fbln5
gene id: 51337:Fbln5
uniprot id: A0A8C5LAY7
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Aqp3
gene id: 51337:Aqp3
uniprot id: A0A8C5K3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

51337:Otop2
gene id: 51337:Otop2
uniprot id: A0A8C5L6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

51337:Iars2
gene id: 51337:Iars2
uniprot id: A0A8C5KUK0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Magi3
gene id: 51337:Magi3
uniprot id: A0A8C5KGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

51337:LOC101611594
gene id: 51337:LOC101611594
uniprot id: A0A8C5KV62
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Hadha
gene id: 51337:Hadha
uniprot id: A0A8C5KZV9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

51337:LOC101605866
gene id: 51337:LOC101605866
uniprot id: A0A8C5KJG1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Dlgap1
gene id: 51337:Dlgap1
uniprot id: A0A8C5KCH0
uniprot id: A0A8C5KH56
names: Similarity
messages: Belongs to the SAPAP family.

51337:Nid1
gene id: 51337:Nid1
uniprot id: A0A8C5KP03
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

51337:Fam120a
gene id: 51337:Fam120a
uniprot id: A0A8C5K9Q5
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

51337:Camk2n1
gene id: 51337:Camk2n1
uniprot id: A0A8C5KY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAMK2N family.
messages: Synapse

51337:Smad6
gene id: 51337:Smad6
uniprot id: A0A8C5L3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

51337:Chmp3
gene id: 51337:Chmp3
uniprot id: A0A8C5KV39
names: Similarity
messages: Belongs to the SNF7 family.

51337:Mrpl40
gene id: 51337:Mrpl40
uniprot id: A0A8C5L0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

51337:Taf13
gene id: 51337:Taf13
uniprot id: A0A8C5KPU1
names: Subcellular Location Annotation
messages: Nucleus

51337:Lbx1
gene id: 51337:Lbx1
uniprot id: A0A8C5LC70
names: Subcellular Location Annotation
messages: Nucleus

51337:Tnfrsf11b
gene id: 51337:Tnfrsf11b
uniprot id: A0A8C5L6D8
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Lig3
gene id: 51337:Lig3
uniprot id: A0A8C5K0Q2
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

51337:Aph1b
gene id: 51337:Aph1b
uniprot id: A0A8C5P251
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

51337:Susd4
gene id: 51337:Susd4
uniprot id: A0A8C5KW53
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Pcid2
gene id: 51337:Pcid2
uniprot id: A0A8C5KG84
names: Similarity
messages: Belongs to the CSN12 family.

51337:Hspb2
gene id: 51337:Hspb2
uniprot id: A0A8C5L9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

51337:Evpl
gene id: 51337:Evpl
uniprot id: A0A8C5KCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plakin or cytolinker family.
messages: cytoskeleton

51337:Katnb1
gene id: 51337:Katnb1
uniprot id: A0A8C5KV07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome. This interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein, microtubules, NDEL1 and PAFAH1B1. Interacts with KATNAL1; this interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

51337:Camk2n2
gene id: 51337:Camk2n2
uniprot id: A0A8C5LJ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAMK2N family.
messages: Synapse

51337:Slc17a9
gene id: 51337:Slc17a9
uniprot id: A0A8C5JU87
names: Subcellular Location Annotation
messages: Membrane

51337:Snd1
gene id: 51337:Snd1
uniprot id: A0A8C5K7F6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

51337:Nxph4
gene id: 51337:Nxph4
uniprot id: A0A8C5K232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

51337:Slc25a40
gene id: 51337:Slc25a40
uniprot id: A0A8C5P1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

51337:Unc5cl
gene id: 51337:Unc5cl
uniprot id: A0A8C5KHQ6
names: Similarity
messages: Belongs to the unc-5 family.

51337:LOC101614775
gene id: 51337:LOC101614775
uniprot id: A0A8C5KZ40
names: Similarity
messages: Belongs to the CEMIP family.

51337:Dhrs7c
gene id: 51337:Dhrs7c
uniprot id: A0A8C5NUD8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Tmed4
gene id: 51337:Tmed4
uniprot id: A0A8C5K0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Atp7a
gene id: 51337:Atp7a
uniprot id: A0A8C5LAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

51337:Bloc1s3
gene id: 51337:Bloc1s3
uniprot id: A0A8C5KJ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

51337:Cdk1
gene id: 51337:Cdk1
uniprot id: A0A8C5KR91
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Clcn3
gene id: 51337:Clcn3
uniprot id: A0A8C5JUW0
uniprot id: A0A8C5JWJ0
uniprot id: A0A8C5JYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

51337:Scamp4
gene id: 51337:Scamp4
uniprot id: A0A8C5LN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

51337:LOC101599167
gene id: 51337:LOC101599167
uniprot id: A0A8C5L9A3
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Vps29
gene id: 51337:Vps29
uniprot id: A0A8C5K6E3
uniprot id: A0A8C5K9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

51337:Tor1a
gene id: 51337:Tor1a
uniprot id: A0A8C5P3K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum lumen
messages: Homohexamer. Interacts with TOR1B; the interaction may be specific of neural tissues. Interacts (ATP-bound) with TOR1AIP1 and TOR1AIP2; the interactions induce ATPase activity. Interacts with KLHL14; preferentially when ATP-free. Interacts with KLC1 (via TPR repeats); the interaction associates TOR1A with the kinesin oligomeric complex. Interacts with COPS4; the interaction associates TOR1A with the CSN complex. Interacts with SNAPIN; the interaction is direct and associates SNAPIN with the CSN complex. Interacts with STON2. Interacts (ATP-bound) with SYNE3 (via KASH domain); the interaction is required for SYNE3 nuclear envelope localization. Interacts with VIM; the interaction associates TOR1A with the cytoskeleton. Interacts with PLEC. Interacts (ATP-bound) with SLC6A3; regulates SLC6A3 transport to the plasma membrane.
messages: Membrane
messages: growth cone

51337:LOC101607586
gene id: 51337:LOC101607586
uniprot id: A0A8C5KK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Lsm5
gene id: 51337:Lsm5
uniprot id: A0A8C5KE69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

51337:Cluap1
gene id: 51337:Cluap1
uniprot id: A0A8C5K1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

51337:Slc25a28
gene id: 51337:Slc25a28
uniprot id: A0A8C5KUN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Mctp2
gene id: 51337:Mctp2
uniprot id: A0A8C5KL10
names: Subcellular Location Annotation
messages: Membrane

51337:Cd180
gene id: 51337:Cd180
uniprot id: A0A8C5KVN6
names: Similarity
messages: Belongs to the Toll-like receptor family.

51337:Clk4
gene id: 51337:Clk4
uniprot id: A0A8C5KPV5
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Ccnd1
gene id: 51337:Ccnd1
uniprot id: A0A8C5P5N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

51337:Fbxo32
gene id: 51337:Fbxo32
uniprot id: A0A8C5KCC1
names: Subcellular Location Annotation
messages: Nucleus

51337:Hoxc12
gene id: 51337:Hoxc12
uniprot id: A0A8C5P5P9
names: Subcellular Location Annotation
messages: Nucleus

51337:Lsm12
gene id: 51337:Lsm12
uniprot id: A0A8C5K0Y2
names: Similarity
messages: Belongs to the LSM12 family.

51337:Cnot3
gene id: 51337:Cnot3
uniprot id: A0A8C5NZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.
messages: Nucleus
messages: P-body

51337:Pgls
gene id: 51337:Pgls
uniprot id: A0A8C5L3R5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

51337:Slc39a5
gene id: 51337:Slc39a5
uniprot id: A0A8C5NX80
names: Subcellular Location Annotation
messages: Membrane

51337:Klc4
gene id: 51337:Klc4
uniprot id: A0A8C5KLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

51337:Agl
gene id: 51337:Agl
uniprot id: A0A8C5L624
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

51337:Btg1
gene id: 51337:Btg1
uniprot id: A0A8C5JXH5
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

51337:Ugcg
gene id: 51337:Ugcg
uniprot id: A0A8C5KN74
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

51337:Dld
gene id: 51337:Dld
uniprot id: A0A8C5KWN3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

51337:Pdk3
gene id: 51337:Pdk3
uniprot id: A0A8C5KZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

51337:Pdk2
gene id: 51337:Pdk2
uniprot id: A0A8C5K9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

51337:Ykt6
gene id: 51337:Ykt6
uniprot id: A0A8C5P5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

51337:Map3k14
gene id: 51337:Map3k14
uniprot id: A0A8C5P206
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

51337:Kcnv2
gene id: 51337:Kcnv2
uniprot id: A0A8C5KYQ6
names: Subcellular Location Annotation
messages: Membrane

51337:Icam2
gene id: 51337:Icam2
uniprot id: A0A8C5KTP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

51337:Ndufs2
gene id: 51337:Ndufs2
uniprot id: A0A8C5KPZ1
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

51337:Ebf2
gene id: 51337:Ebf2
uniprot id: A0A8C5P1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

51337:Pde4b
gene id: 51337:Pde4b
uniprot id: A0A8C5KMS6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Nuf2
gene id: 51337:Nuf2
uniprot id: A0A8C5KLQ0
names: Similarity
messages: Belongs to the NUF2 family.

51337:Vat1l
gene id: 51337:Vat1l
uniprot id: A0A8C5P537
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

51337:Gle1
gene id: 51337:Gle1
uniprot id: A0A8C5L8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

51337:LOC101594050
gene id: 51337:LOC101594050
uniprot id: A0A8C5KIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:LOC101617737
gene id: 51337:LOC101617737
uniprot id: A0A8C5P5P6
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Iscu
gene id: 51337:Iscu
uniprot id: A0A8C5JZ75
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

51337:Csnk1a1
gene id: 51337:Csnk1a1
uniprot id: A0A8C5KXX8
uniprot id: A0A8C5L1F4
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Oprk1
gene id: 51337:Oprk1
uniprot id: A0A8C5L719
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with SLC9A3R1. Interacts with GABARAPL1.
messages: Membrane

51337:Tgfbi
gene id: 51337:Tgfbi
uniprot id: A0A8C5KLE2
names: Subcellular Location Annotation
messages: extracellular matrix

51337:Ergic3
gene id: 51337:Ergic3
uniprot id: A0A8C5L2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

51337:Gls2
gene id: 51337:Gls2
uniprot id: A0A8C5L985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutaminase family.
messages: Mitochondrion

51337:Foxn3
gene id: 51337:Foxn3
uniprot id: A0A8C5KZ52
uniprot id: A0A8C5P2J3
names: Subcellular Location Annotation
messages: Nucleus

51337:Fahd2a
gene id: 51337:Fahd2a
uniprot id: A0A8C5P2U4
names: Similarity
messages: Belongs to the FAH family.

51337:Timp4
gene id: 51337:Timp4
uniprot id: A0A8C5KRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

51337:Fxr2
gene id: 51337:Fxr2
uniprot id: A0A8C5KXL2
names: Similarity
messages: Belongs to the FMR1 family.

51337:Chrm2
gene id: 51337:Chrm2
uniprot id: A0A8C5JWY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

51337:Tagln
gene id: 51337:Tagln
uniprot id: A0A8C5K8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calponin family.
messages: Cytoplasm

51337:Gast
gene id: 51337:Gast
uniprot id: A0A8C5L5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

51337:Mrpl20
gene id: 51337:Mrpl20
uniprot id: A0A8C5LBS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

51337:Psmf1
gene id: 51337:Psmf1
uniprot id: A0A8C5KJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

51337:Lmbr1l
gene id: 51337:Lmbr1l
uniprot id: A0A8C5JZ70
names: Similarity
messages: Belongs to the LIMR family.

51337:Hspb6
gene id: 51337:Hspb6
uniprot id: A0A8C5KJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

51337:Man1a2
gene id: 51337:Man1a2
uniprot id: A0A8C5KV82
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

51337:Myh7
gene id: 51337:Myh7
uniprot id: A0A8C5KUE1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Grm2
gene id: 51337:Grm2
uniprot id: A0A8C5L276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

51337:Alx1
gene id: 51337:Alx1
uniprot id: A0A8C5NVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

51337:Habp4
gene id: 51337:Habp4
uniprot id: A0A8C5KQV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Zc3h12b
gene id: 51337:Zc3h12b
uniprot id: A0A8C5P0C1
names: Similarity
messages: Belongs to the ZC3H12 family.

51337:Slc17a4
gene id: 51337:Slc17a4
uniprot id: A0A8C5KJ39
names: Subcellular Location Annotation
messages: Membrane

51337:Atp5mc1
gene id: 51337:Atp5mc1
uniprot id: A0A8C5NWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

51337:Capn8
gene id: 51337:Capn8
uniprot id: A0A8C5P1D6
names: Similarity
messages: Belongs to the peptidase C2 family.

51337:Cnih3
gene id: 51337:Cnih3
uniprot id: A0A8C5P588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

51337:St3gal2
gene id: 51337:St3gal2
uniprot id: A0A8C5K3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Dlx6
gene id: 51337:Dlx6
uniprot id: A0A8C5K6V1
names: Subcellular Location Annotation
messages: Nucleus

51337:Gins3
gene id: 51337:Gins3
uniprot id: A0A8C5KG52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

51337:Slc16a12
gene id: 51337:Slc16a12
uniprot id: A0A8C5KMP2
names: Subcellular Location Annotation
messages: Membrane

51337:Cers2
gene id: 51337:Cers2
uniprot id: A0A8C5P2A6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

51337:Ctbp2
gene id: 51337:Ctbp2
uniprot id: A0A8C5L884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

51337:LOC101596677
gene id: 51337:LOC101596677
uniprot id: A0A8C5KFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

51337:Slc30a7
gene id: 51337:Slc30a7
uniprot id: A0A8C5K2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

51337:Kpna6
gene id: 51337:Kpna6
uniprot id: A0A8C5KM06
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

51337:B4galt2
gene id: 51337:B4galt2
uniprot id: A0A8C5K5T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

51337:Rps3a
gene id: 51337:Rps3a
uniprot id: A0A8C5LBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus

51337:LOC101611786
gene id: 51337:LOC101611786
uniprot id: A0A8C5K0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

51337:Tmeff2
gene id: 51337:Tmeff2
uniprot id: A0A8C5KK81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Cfdp1
gene id: 51337:Cfdp1
uniprot id: A0A8C5L152
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

51337:Tubgcp3
gene id: 51337:Tubgcp3
uniprot id: A0A8C5KM40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

51337:Gmpr2
gene id: 51337:Gmpr2
uniprot id: A0A8C5P0S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

51337:Ostc
gene id: 51337:Ostc
uniprot id: A0A8C5K9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

51337:Adprh
gene id: 51337:Adprh
uniprot id: A0A8C5KNV7
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

51337:Rer1
gene id: 51337:Rer1
uniprot id: A0A8C5P2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

51337:LOC101593744
gene id: 51337:LOC101593744
uniprot id: A0A8C5NYA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Slc39a3
gene id: 51337:Slc39a3
uniprot id: A0A8C5KJ46
names: Subcellular Location Annotation
messages: Membrane

51337:Ccbe1
gene id: 51337:Ccbe1
uniprot id: A0A8C5KA58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Rps16
gene id: 51337:Rps16
uniprot id: A0A8C5JV90
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

51337:Stag2
gene id: 51337:Stag2
uniprot id: A0A8C5L2F3
uniprot id: A0A8C5L8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

51337:LOC101610613
gene id: 51337:LOC101610613
uniprot id: A0A8C5KAJ3
names: Similarity
messages: Belongs to the NipSnap family.

51337:Pla2g2f
gene id: 51337:Pla2g2f
uniprot id: A0A8C5KPH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

51337:Tm6sf1
gene id: 51337:Tm6sf1
uniprot id: A0A8C5K9P2
names: Subcellular Location Annotation
messages: Membrane

51337:Rnf10
gene id: 51337:Rnf10
uniprot id: A0A8C5L1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

51337:Cplx2
gene id: 51337:Cplx2
uniprot id: A0A8C5KAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

51337:Kcnj10
gene id: 51337:Kcnj10
uniprot id: A0A8C5JVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

51337:Dlk1
gene id: 51337:Dlk1
uniprot id: A0A8C5L3E8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Calu
gene id: 51337:Calu
uniprot id: A0A8C5L1W9
uniprot id: A0A8C5L8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

51337:Mrps15
gene id: 51337:Mrps15
uniprot id: A0A8C5LDU3
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

51337:Vta1
gene id: 51337:Vta1
uniprot id: A0A8C5LJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

51337:Bves
gene id: 51337:Bves
uniprot id: A0A8C5KF31
names: Similarity
messages: Belongs to the popeye family.

51337:LOC101603730
gene id: 51337:LOC101603730
uniprot id: A0A8C5JX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Serpinh1
gene id: 51337:Serpinh1
uniprot id: A0A8C5LFD8
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

51337:LOC101596787
gene id: 51337:LOC101596787
uniprot id: A0A8C5K6L6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Rag1
gene id: 51337:Rag1
uniprot id: A0A8C5NUW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

51337:Sptan1
gene id: 51337:Sptan1
uniprot id: A0A8C5K4X7
uniprot id: A0A8C5K7B9
uniprot id: A0A8C5K7F3
uniprot id: A0A8C5K854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

51337:Pigg
gene id: 51337:Pigg
uniprot id: A0A8C5K6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101600615
gene id: 51337:LOC101600615
uniprot id: A0A8C5KG27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Ube2m
gene id: 51337:Ube2m
uniprot id: A0A8C5K1Y1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:B3galt2
gene id: 51337:B3galt2
uniprot id: A0A8C5K8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Maea
gene id: 51337:Maea
uniprot id: A0A8C5KXC2
names: Subcellular Location Annotation
messages: Nucleus matrix
messages: nucleoplasm

51337:Thyn1
gene id: 51337:Thyn1
uniprot id: A0A8C5KU79
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

51337:LOC101604227
gene id: 51337:LOC101604227
uniprot id: A0A8C5LF96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:LOC105943929
gene id: 51337:LOC105943929
uniprot id: A0A8C5K5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

51337:Lims1
gene id: 51337:Lims1
uniprot id: A0A8C5KYK2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

51337:Map2k3
gene id: 51337:Map2k3
uniprot id: A0A8C5KQ80
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Med26
gene id: 51337:Med26
uniprot id: A0A8C5L2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

51337:Actg1
gene id: 51337:Actg1
uniprot id: A0A8C5KSH3
names: Similarity
messages: Belongs to the actin family.

51337:Naxe
gene id: 51337:Naxe
uniprot id: A0A8C5LGU9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
messages: Homodimer. Interacts with APOA1 and APOA2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted
messages: Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.

51337:LOC101616822
gene id: 51337:LOC101616822
uniprot id: A0A8C5NUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

51337:Arhgap32
gene id: 51337:Arhgap32
uniprot id: A0A8C5L465
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

51337:Ywhag
gene id: 51337:Ywhag
uniprot id: A0A8C5P618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

51337:Riok1
gene id: 51337:Riok1
uniprot id: A0A8C5NZY0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

51337:Azin2
gene id: 51337:Azin2
uniprot id: A0A8C5KUM5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

51337:Dpf2
gene id: 51337:Dpf2
uniprot id: A0A8C5KY90
names: Similarity
messages: Belongs to the requiem/DPF family.

51337:Sfn
gene id: 51337:Sfn
uniprot id: A0A8C5NYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

51337:Galnt17
gene id: 51337:Galnt17
uniprot id: A0A8C5K332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:LOC101599252
gene id: 51337:LOC101599252
uniprot id: A0A8C5K9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

51337:Cdc42bpa
gene id: 51337:Cdc42bpa
uniprot id: A0A8C5K5G7
uniprot id: A0A8C5K727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

51337:Actr8
gene id: 51337:Actr8
uniprot id: A0A8C5L253
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

51337:LOC101615472
gene id: 51337:LOC101615472
uniprot id: A0A8C5L627
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

51337:Ddit3
gene id: 51337:Ddit3
uniprot id: A0A8C5KD96
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Cytoplasm
messages: Heterodimer.
messages: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
messages: Nucleus
messages: Phosphorylation at serine residues by MAPK14 enhances its transcriptional activation activity while phosphorylation at serine residues by CK2 inhibits its transcriptional activation activity.
messages: Ubiquitinated, leading to its degradation by the proteasome.

51337:Bace2
gene id: 51337:Bace2
uniprot id: A0A8C5K6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane

51337:Cad
gene id: 51337:Cad
uniprot id: A0A8C5LET3
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

51337:KEG00 p11
gene id: 51337:KEG00_p11
uniprot id: Q710T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Tgif1
gene id: 51337:Tgif1
uniprot id: A0A8C5K4L8
uniprot id: A0A8C5K7H8
names: Subcellular Location Annotation
messages: Nucleus

51337:Emc3
gene id: 51337:Emc3
uniprot id: A0A8C5L546
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

51337:Guk1
gene id: 51337:Guk1
uniprot id: A0A8C5LEW2
names: Similarity
messages: Belongs to the guanylate kinase family.

51337:Rxrg
gene id: 51337:Rxrg
uniprot id: A0A8C5KX76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

51337:Ptpa
gene id: 51337:Ptpa
uniprot id: A0A8C5L3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

51337:Gclc
gene id: 51337:Gclc
uniprot id: A0A8C5LLI1
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

51337:Ganab
gene id: 51337:Ganab
uniprot id: A0A8C5P5I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

51337:Tek
gene id: 51337:Tek
uniprot id: A0A8C5L3L8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Gfus
gene id: 51337:Gfus
uniprot id: A0A8C5KQY0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

51337:Msrb3
gene id: 51337:Msrb3
uniprot id: A0A8C5KW22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

51337:Lyn
gene id: 51337:Lyn
uniprot id: A0A8C5KNJ1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:Tns4
gene id: 51337:Tns4
uniprot id: A0A8C5JY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

51337:B3gnt8
gene id: 51337:B3gnt8
uniprot id: A0A8C5NYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Gpatch1
gene id: 51337:Gpatch1
uniprot id: A0A8C5LM03
names: Similarity
messages: Belongs to the GPATCH1 family.

51337:LOC101611837
gene id: 51337:LOC101611837
uniprot id: A0A8C5KGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Creb3l3
gene id: 51337:Creb3l3
uniprot id: A0A8C5P2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Atp13a4
gene id: 51337:Atp13a4
uniprot id: A0A8C5LHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

51337:Coro6
gene id: 51337:Coro6
uniprot id: A0A8C5JV20
names: Similarity
messages: Belongs to the WD repeat coronin family.

51337:Hoxc4
gene id: 51337:Hoxc4
uniprot id: A0A8C5KSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Actr1b
gene id: 51337:Actr1b
uniprot id: A0A8C5KW62
names: Similarity
messages: Belongs to the actin family.

51337:Kif16b
gene id: 51337:Kif16b
uniprot id: A0A8C5K417
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Pex7
gene id: 51337:Pex7
uniprot id: A0A8C5KNL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

51337:LOC101601747
gene id: 51337:LOC101601747
uniprot id: A0A8C5LH97
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

51337:Mlec
gene id: 51337:Mlec
uniprot id: A0A8C5L179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Hbp1
gene id: 51337:Hbp1
uniprot id: A0A8C5KKI2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

51337:Mapkap1
gene id: 51337:Mapkap1
uniprot id: A0A8C5KMC8
uniprot id: A0A8C5KP36
names: Similarity
messages: Belongs to the SIN1 family.

51337:Prdm1
gene id: 51337:Prdm1
uniprot id: A0A8C5LDR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

51337:Cks2
gene id: 51337:Cks2
uniprot id: A0A8C5L635
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

51337:LOC101611600
gene id: 51337:LOC101611600
uniprot id: A0A8C5K822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tgfb1
gene id: 51337:Tgfb1
uniprot id: A0A8C5KG99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

51337:Pop7
gene id: 51337:Pop7
uniprot id: A0A8C5NVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

51337:Pip4p1
gene id: 51337:Pip4p1
uniprot id: A0A8C5KCT5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

51337:Tppp3
gene id: 51337:Tppp3
uniprot id: A0A8C5NYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: cytoskeleton

51337:Septin2
gene id: 51337:Septin2
uniprot id: A0A8C5L2D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

51337:Hoxb9
gene id: 51337:Hoxb9
uniprot id: A0A8C5K9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

51337:Chn2
gene id: 51337:Chn2
uniprot id: A0A8C5LFT8
names: Function
messages: GTPase-activating protein for p21-rac.

51337:C12H5orf63
gene id: 51337:C12H5orf63
uniprot id: A0A8C5KMQ9
names: Similarity
messages: Belongs to the glutaredoxin family.

51337:Jph4
gene id: 51337:Jph4
uniprot id: A0A8C5P002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

51337:LOC101602610
gene id: 51337:LOC101602610
uniprot id: A0A8C5KP44
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

51337:Serpinb5
gene id: 51337:Serpinb5
uniprot id: A0A8C5KQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

51337:Egr1
gene id: 51337:Egr1
uniprot id: A0A8C5KK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

51337:Lamtor2
gene id: 51337:Lamtor2
uniprot id: A0A8C5L8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

51337:Pacs1
gene id: 51337:Pacs1
uniprot id: A0A8C5KER8
names: Similarity
messages: Belongs to the PACS family.

51337:Sfmbt1
gene id: 51337:Sfmbt1
uniprot id: A0A8C5LCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

51337:LOC101604468
gene id: 51337:LOC101604468
uniprot id: A0A8C5KT25
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

51337:Rps19
gene id: 51337:Rps19
uniprot id: A0A8C5P0C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: Interacts with RPS19BP1.
messages: Required for pre-rRNA processing and maturation of 40S ribosomal subunits.

51337:Rap2c
gene id: 51337:Rap2c
uniprot id: A0A8C5KIF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

51337:Fam76b
gene id: 51337:Fam76b
uniprot id: A0A8C5KY26
names: Similarity
messages: Belongs to the FAM76 family.

51337:Gng11
gene id: 51337:Gng11
uniprot id: A0A8C5KMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:Usp2
gene id: 51337:Usp2
uniprot id: A0A8C5KBN6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

51337:Atp6v1g3
gene id: 51337:Atp6v1g3
uniprot id: A0A8C5LDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Clptm1l
gene id: 51337:Clptm1l
uniprot id: A0A8C5KY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

51337:Slc45a3
gene id: 51337:Slc45a3
uniprot id: A0A8C5JXS3
names: Subcellular Location Annotation
messages: Membrane

51337:Aif1
gene id: 51337:Aif1
uniprot id: A0A8C5K1T1
names: Subcellular Location Annotation
messages: ruffle membrane

51337:Pdcd10
gene id: 51337:Pdcd10
uniprot id: A0A8C5K446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

51337:Pabpc1
gene id: 51337:Pabpc1
uniprot id: A0A8C5KU90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

51337:Acvr2a
gene id: 51337:Acvr2a
uniprot id: A0A8C5KN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

51337:Gabarapl1
gene id: 51337:Gabarapl1
uniprot id: A0A8C5K7U1
names: Similarity
messages: Belongs to the ATG8 family.

51337:Hsf4
gene id: 51337:Hsf4
uniprot id: A0A8C5K129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

51337:Arid5b
gene id: 51337:Arid5b
uniprot id: A0A8C5K2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARID5B family.
messages: Nucleus

51337:Pax6
gene id: 51337:Pax6
uniprot id: A0A8C5K9S7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Cdip1
gene id: 51337:Cdip1
uniprot id: A0A8C5KKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

51337:Kat7
gene id: 51337:Kat7
uniprot id: A0A8C5KCQ0
uniprot id: A0A8C5NWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

51337:Ltbp3
gene id: 51337:Ltbp3
uniprot id: A0A8C5LC40
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

51337:Pggt1b
gene id: 51337:Pggt1b
uniprot id: A0A8C5LA85
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

51337:Mapre3
gene id: 51337:Mapre3
uniprot id: A0A8C5KTP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

51337:Mab21l1
gene id: 51337:Mab21l1
uniprot id: A0A8C5KHB6
names: Similarity
messages: Belongs to the mab-21 family.

51337:Atl1
gene id: 51337:Atl1
uniprot id: A0A8C5KAM4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

51337:Prkar2b
gene id: 51337:Prkar2b
uniprot id: A0A8C5KN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

51337:Lcorl
gene id: 51337:Lcorl
uniprot id: A0A8C5L5T0
names: Subcellular Location Annotation
messages: Nucleus

51337:Tac1
gene id: 51337:Tac1
uniprot id: A0A8C5KFK5
uniprot id: A0A8C5KJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

51337:Ccdc22
gene id: 51337:Ccdc22
uniprot id: A0A8C5L8B4
names: Similarity
messages: Belongs to the CCDC22 family.

51337:Adprm
gene id: 51337:Adprm
uniprot id: A0A8C5L528
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

51337:Mief2
gene id: 51337:Mief2
uniprot id: A0A8C5NUG1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

51337:Sorl1
gene id: 51337:Sorl1
uniprot id: A0A8C5KWV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

51337:Xkr8
gene id: 51337:Xkr8
uniprot id: A0A8C5KT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

51337:Cactin
gene id: 51337:Cactin
uniprot id: A0A8C5LAL4
names: Similarity
messages: Belongs to the CACTIN family.

51337:Sh3gl3
gene id: 51337:Sh3gl3
uniprot id: A0A8C5K3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
messages: Membrane

51337:Gata2
gene id: 51337:Gata2
uniprot id: A0A8C5KTS4
names: Subcellular Location Annotation
messages: Nucleus

51337:Pde6h
gene id: 51337:Pde6h
uniprot id: A0A8C5P064
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

51337:Manea
gene id: 51337:Manea
uniprot id: A0A8C5LH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Slc25a43
gene id: 51337:Slc25a43
uniprot id: A0A8C5P4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Bivm
gene id: 51337:Bivm
uniprot id: A0A8C5LJ33
names: Similarity
messages: Belongs to the BIVM family.

51337:Pnpt1
gene id: 51337:Pnpt1
uniprot id: A0A8C5P2Q4
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

51337:Tmlhe
gene id: 51337:Tmlhe
uniprot id: A0A8C5KZ02
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

51337:Cldn1
gene id: 51337:Cldn1
uniprot id: A0A8C5NVL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Mak16
gene id: 51337:Mak16
uniprot id: A0A8C5NZZ7
names: Similarity
messages: Belongs to the MAK16 family.

51337:Msx2
gene id: 51337:Msx2
uniprot id: A0A8C5KVB1
names: Subcellular Location Annotation
messages: Nucleus

51337:Otx1
gene id: 51337:Otx1
uniprot id: A0A8C5KEW6
names: Subcellular Location Annotation
messages: Nucleus

51337:Mmgt1
gene id: 51337:Mmgt1
uniprot id: A0A8C5K4E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

51337:Gpt2
gene id: 51337:Gpt2
uniprot id: A0A8C5KSK0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

51337:Spock3
gene id: 51337:Spock3
uniprot id: A0A8C5KJ30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101608122
gene id: 51337:LOC101608122
uniprot id: A0A8C5KW99
names: Similarity
messages: Belongs to the DEAD box helicase family.

51337:Il1a
gene id: 51337:Il1a
uniprot id: A0A8C5K931
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: Secreted

51337:Irx2
gene id: 51337:Irx2
uniprot id: A0A8C5K609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

51337:Mief1
gene id: 51337:Mief1
uniprot id: A0A8C5KS69
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

51337:Kcna10
gene id: 51337:Kcna10
uniprot id: A0A8C5K1B1
names: Subcellular Location Annotation
messages: Membrane

51337:Ggh
gene id: 51337:Ggh
uniprot id: A0A8C5L628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

51337:Prkcb
gene id: 51337:Prkcb
uniprot id: A0A8C5JZW0
uniprot id: A0A8C5NVQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

51337:Tbl3
gene id: 51337:Tbl3
uniprot id: A0A8C5K1P2
names: Subcellular Location Annotation
messages: nucleolus

51337:Tmod3
gene id: 51337:Tmod3
uniprot id: A0A8C5KGW3
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Cdh11
gene id: 51337:Cdh11
uniprot id: A0A8C5KHR7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

51337:Atp9b
gene id: 51337:Atp9b
uniprot id: A0A8C5NXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

51337:Tmem115
gene id: 51337:Tmem115
uniprot id: A0A8C5JVS7
names: Subcellular Location Annotation
messages: Membrane

51337:Higd2a
gene id: 51337:Higd2a
uniprot id: A0A8C5L806
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

51337:Ss18l2
gene id: 51337:Ss18l2
uniprot id: A0A8C5KKI1
names: Similarity
messages: Belongs to the SS18 family.

51337:Tbx20
gene id: 51337:Tbx20
uniprot id: A0A8C5KVK1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Engase
gene id: 51337:Engase
uniprot id: A0A8C5L0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

51337:Dok1
gene id: 51337:Dok1
uniprot id: A0A8C5K4B2
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

51337:LOC101600196
gene id: 51337:LOC101600196
uniprot id: A0A8C5KXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

51337:LOC101610966
gene id: 51337:LOC101610966
uniprot id: A0A8C5KCK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Syn1
gene id: 51337:Syn1
uniprot id: A0A8C5L8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synapsin family.
messages: Golgi apparatus
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: synaptic vesicle

51337:Gmpr
gene id: 51337:Gmpr
uniprot id: A0A8C5NU67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

51337:LOC101593657
gene id: 51337:LOC101593657
uniprot id: A0A8C5NY38
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

51337:Ube2f
gene id: 51337:Ube2f
uniprot id: A0A8C5KR72
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Stx2
gene id: 51337:Stx2
uniprot id: A0A8C5KA94
uniprot id: A0A8C5NX24
names: Similarity
messages: Belongs to the syntaxin family.

51337:Gtf2b
gene id: 51337:Gtf2b
uniprot id: A0A8C5KXK3
names: Similarity
messages: Belongs to the TFIIB family.

51337:Slc25a42
gene id: 51337:Slc25a42
uniprot id: A0A8C5L4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:LOC101611170
gene id: 51337:LOC101611170
uniprot id: A0A8C5KFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

51337:Mrpl54
gene id: 51337:Mrpl54
uniprot id: A0A8C5L698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

51337:LOC101609669
gene id: 51337:LOC101609669
uniprot id: A0A8C5K561
names: Similarity
messages: Belongs to the DPH3 family.

51337:Ak5
gene id: 51337:Ak5
uniprot id: A0A8C5NYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

51337:Slc30a4
gene id: 51337:Slc30a4
uniprot id: A0A8C5LE67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

51337:Prkg1
gene id: 51337:Prkg1
uniprot id: A0A8C5KS43
uniprot id: A0A8C5NZY8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

51337:Rragd
gene id: 51337:Rragd
uniprot id: A0A8C5NUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

51337:Tspo2
gene id: 51337:Tspo2
uniprot id: A0A8C5K977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

51337:Smc2
gene id: 51337:Smc2
uniprot id: A0A8C5P5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

51337:LOC101595185
gene id: 51337:LOC101595185
uniprot id: A0A8C5L7V0
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Gnat2
gene id: 51337:Gnat2
uniprot id: A0A8C5KZE8
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

51337:Shank2
gene id: 51337:Shank2
uniprot id: A0A8C5KTC2
uniprot id: A0A8C5KTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHANK family.
messages: Cytoplasm
messages: Postsynaptic density

51337:Arpc5l
gene id: 51337:Arpc5l
uniprot id: A0A8C5KJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
messages: May be a component of the Arp2/3 complex in which it may replace ARPC5.
messages: May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

51337:Eif5a2
gene id: 51337:Eif5a2
uniprot id: A0A8C5KJS7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

51337:Serf1a
gene id: 51337:Serf1a
uniprot id: A0A8C5KQ83
names: Similarity
messages: Belongs to the SERF family.

51337:Ppp1r16b
gene id: 51337:Ppp1r16b
uniprot id: A0A8C5JZM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Slc49a3
gene id: 51337:Slc49a3
uniprot id: A0A8C5L9A0
names: Subcellular Location Annotation
messages: Membrane

51337:Htr2b
gene id: 51337:Htr2b
uniprot id: A0A8C5P0B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts (via C-terminus) with MPDZ.
messages: Membrane
messages: synaptosome

51337:Psmg1
gene id: 51337:Psmg1
uniprot id: A0A8C5JUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
messages: Forms a heterodimer with psmg2.

51337:LOC101613872
gene id: 51337:LOC101613872
uniprot id: A0A8C5KG47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Sypl2
gene id: 51337:Sypl2
uniprot id: A0A8C5L8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

51337:Rpa3
gene id: 51337:Rpa3
uniprot id: A0A8C5K4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

51337:Tradd
gene id: 51337:Tradd
uniprot id: A0A8C5K4W4
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

51337:Lmx1b
gene id: 51337:Lmx1b
uniprot id: A0A8C5P158
names: Subcellular Location Annotation
messages: Nucleus

51337:Dph3
gene id: 51337:Dph3
uniprot id: A0A8C5K561
names: Similarity
messages: Belongs to the DPH3 family.

51337:Rasgrp2
gene id: 51337:Rasgrp2
uniprot id: A0A8C5JZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RASGRP family.
messages: cytosol

51337:Rfng
gene id: 51337:Rfng
uniprot id: A0A8C5JVG3
names: Subcellular Location Annotation
messages: Membrane

51337:Metrnl
gene id: 51337:Metrnl
uniprot id: A0A8C5KB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

51337:Fgf5
gene id: 51337:Fgf5
uniprot id: A0A8C5KPF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

51337:Cenpb
gene id: 51337:Cenpb
uniprot id: A0A8C5NUM6
names: Subcellular Location Annotation
messages: Nucleus

51337:Bysl
gene id: 51337:Bysl
uniprot id: A0A8C5P5E1
names: Similarity
messages: Belongs to the bystin family.

51337:Plpp4
gene id: 51337:Plpp4
uniprot id: A0A8C5P572
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

51337:Akap3
gene id: 51337:Akap3
uniprot id: A0A8C5K662
names: Similarity
messages: Belongs to the AKAP110 family.

51337:Dpf1
gene id: 51337:Dpf1
uniprot id: A0A8C5KFZ5
uniprot id: A0A8C5KIA3
names: Similarity
messages: Belongs to the requiem/DPF family.

51337:LOC101597646
gene id: 51337:LOC101597646
uniprot id: A0A8C5NY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Cndp2
gene id: 51337:Cndp2
uniprot id: A0A8C5KNF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

51337:Cckar
gene id: 51337:Cckar
uniprot id: A0A8C5K6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

51337:Cryz
gene id: 51337:Cryz
uniprot id: A0A8C5JY19
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

51337:Znf706
gene id: 51337:Znf706
uniprot id: A0A8C5NTX2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Clcn2
gene id: 51337:Clcn2
uniprot id: A0A8C5KLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

51337:Slc16a13
gene id: 51337:Slc16a13
uniprot id: A0A8C5P3H4
names: Subcellular Location Annotation
messages: Membrane

51337:Slc6a1
gene id: 51337:Slc6a1
uniprot id: A0A8C5KGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:C1qa
gene id: 51337:C1qa
uniprot id: A0A8C5KSE8
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

51337:Mterf4
gene id: 51337:Mterf4
uniprot id: A0A8C5JW79
names: Similarity
messages: Belongs to the mTERF family.

51337:Trpv1
gene id: 51337:Trpv1
uniprot id: A0A8C5K860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendritic spine membrane

51337:Slc10a4
gene id: 51337:Slc10a4
uniprot id: A0A8C5KP08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

51337:Iqcd
gene id: 51337:Iqcd
uniprot id: A0A8C5NYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

51337:Sfpq
gene id: 51337:Sfpq
uniprot id: A0A8C5P092
names: Subcellular Location Annotation
messages: Nucleus speckle

51337:LOC101616241
gene id: 51337:LOC101616241
uniprot id: A0A8C5K397
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

51337:LOC101599980
gene id: 51337:LOC101599980
uniprot id: A0A8C5KR44
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Glud1
gene id: 51337:Glud1
uniprot id: A0A8C5P2Q0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

51337:Rnpepl1
gene id: 51337:Rnpepl1
uniprot id: A0A8C5K5S5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

51337:LOC101605943
gene id: 51337:LOC101605943
uniprot id: A0A8C5KDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Yae1
gene id: 51337:Yae1
uniprot id: A0A8C5KW58
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Cplane2
gene id: 51337:Cplane2
uniprot id: A0A8C5L8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

51337:Atp13a5
gene id: 51337:Atp13a5
uniprot id: A0A8C5JU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

51337:Ihh
gene id: 51337:Ihh
uniprot id: A0A8C5K5G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: Secreted
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

51337:Acsl5
gene id: 51337:Acsl5
uniprot id: A0A8C5JZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane

51337:Agbl5
gene id: 51337:Agbl5
uniprot id: A0A8C5L2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

51337:Becn1
gene id: 51337:Becn1
uniprot id: A0A8C5LDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

51337:Steap1
gene id: 51337:Steap1
uniprot id: A0A8C5K1E5
names: Subcellular Location Annotation
messages: Membrane

51337:Mapk9
gene id: 51337:Mapk9
uniprot id: A0A8C5NXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

51337:LOC101607543
gene id: 51337:LOC101607543
uniprot id: A0A8C5KJV6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

51337:Peli2
gene id: 51337:Peli2
uniprot id: A0A8C5K1G4
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

51337:Noc3l
gene id: 51337:Noc3l
uniprot id: A0A8C5L0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

51337:Itfg1
gene id: 51337:Itfg1
uniprot id: A0A8C5KST3
names: Similarity
messages: Belongs to the TIP family.

51337:S100a8
gene id: 51337:S100a8
uniprot id: A0A8C5K3P1
names: Similarity
messages: Belongs to the S-100 family.

51337:Csf1r
gene id: 51337:Csf1r
uniprot id: A0A8C5LF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

51337:Txn
gene id: 51337:Txn
uniprot id: A0A8C5NUM5
names: Similarity
messages: Belongs to the thioredoxin family.

51337:Creld1
gene id: 51337:Creld1
uniprot id: A0A8C5LHV7
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Dnajb12
gene id: 51337:Dnajb12
uniprot id: A0A8C5KBJ8
names: Subcellular Location Annotation
messages: Membrane

51337:Ddo
gene id: 51337:Ddo
uniprot id: A0A8C5KY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

51337:Tbrg1
gene id: 51337:Tbrg1
uniprot id: A0A8C5L4M5
names: Subcellular Location Annotation
messages: Nucleus

51337:Hmgcr
gene id: 51337:Hmgcr
uniprot id: A0A8C5K656
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

51337:Aldh8a1
gene id: 51337:Aldh8a1
uniprot id: A0A8C5KKK2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

51337:Tmem255a
gene id: 51337:Tmem255a
uniprot id: A0A8C5KD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

51337:Rabggtb
gene id: 51337:Rabggtb
uniprot id: A0A8C5LG94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

51337:Fgd4
gene id: 51337:Fgd4
uniprot id: A0A8C5L0V0
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Isoc1
gene id: 51337:Isoc1
uniprot id: A0A8C5L3H0
names: Similarity
messages: Belongs to the isochorismatase family.

51337:Jakmip1
gene id: 51337:Jakmip1
uniprot id: A0A8C5K7W5
names: Similarity
messages: Belongs to the JAKMIP family.

51337:Eef1g
gene id: 51337:Eef1g
uniprot id: A0A8C5L5N6
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

51337:Foxj3
gene id: 51337:Foxj3
uniprot id: A0A8C5P1I3
names: Subcellular Location Annotation
messages: Nucleus

51337:Izumo1r
gene id: 51337:Izumo1r
uniprot id: A0A8C5L2Y6
names: Similarity
messages: Belongs to the folate receptor family.

51337:Gata1
gene id: 51337:Gata1
uniprot id: A0A8C5K909
names: Subcellular Location Annotation
messages: Nucleus

51337:Anxa6
gene id: 51337:Anxa6
uniprot id: A0A8C5L430
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

51337:Stmn3
gene id: 51337:Stmn3
uniprot id: A0A8C5LD10
names: Function
names: Similarity
messages: Belongs to the stathmin family.
messages: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.

51337:LOC101600216
gene id: 51337:LOC101600216
uniprot id: A0A8C5K1L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system
messages: Probably involved in the organization of the actin cytoskeleton.
messages: cytoskeleton

51337:Rho
gene id: 51337:Rho
uniprot id: A0A8C5L8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

51337:LOC101600217
gene id: 51337:LOC101600217
uniprot id: A0A8C5K312
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

51337:Nif3l1
gene id: 51337:Nif3l1
uniprot id: A0A8C5KBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

51337:Itgb6
gene id: 51337:Itgb6
uniprot id: A0A8C5NY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane
messages: focal adhesion

51337:Arl11
gene id: 51337:Arl11
uniprot id: A0A8C5NUY7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

51337:Gabarapl2
gene id: 51337:Gabarapl2
uniprot id: A0A8C5KSV0
names: Similarity
messages: Belongs to the ATG8 family.

51337:Fgf6
gene id: 51337:Fgf6
uniprot id: A0A8C5KDR0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Carm1
gene id: 51337:Carm1
uniprot id: A0A8C5K7I4
names: Subcellular Location Annotation
messages: Nucleus

51337:Pkm
gene id: 51337:Pkm
uniprot id: A0A8C5K1H9
names: Similarity
messages: Belongs to the pyruvate kinase family.

51337:Kcnd2
gene id: 51337:Kcnd2
uniprot id: A0A8C5NTX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

51337:Tlcd1
gene id: 51337:Tlcd1
uniprot id: A0A8C5KA29
names: Subcellular Location Annotation
messages: Membrane

51337:Brinp2
gene id: 51337:Brinp2
uniprot id: A0A8C5KQJ2
names: Similarity
messages: Belongs to the BRINP family.

51337:Kcnj11
gene id: 51337:Kcnj11
uniprot id: A0A8C5NXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

51337:Cfap206
gene id: 51337:Cfap206
uniprot id: A0A8C5P3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

51337:Dmrta2
gene id: 51337:Dmrta2
uniprot id: A0A8C5LB32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

51337:Ppp2r3c
gene id: 51337:Ppp2r3c
uniprot id: A0A8C5KWS1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Rpl18a
gene id: 51337:Rpl18a
uniprot id: A0A8C5K7B4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

51337:Ptprn
gene id: 51337:Ptprn
uniprot id: A0A8C5P1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

51337:Opn1sw
gene id: 51337:Opn1sw
uniprot id: A0A8C5NU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

51337:Pfdn2
gene id: 51337:Pfdn2
uniprot id: A0A8C5JUH8
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

51337:Adat2
gene id: 51337:Adat2
uniprot id: A0A8C5LF24
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
messages: Probably participates in deamination of adenosine-34 to inosine in many tRNAs.

51337:Slc24a5
gene id: 51337:Slc24a5
uniprot id: A0A8C5KWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

51337:Amigo3
gene id: 51337:Amigo3
uniprot id: A0A8C5K8H5
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

51337:Tmsb4x
gene id: 51337:Tmsb4x
uniprot id: A0A8C5K7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

51337:Tmem208
gene id: 51337:Tmem208
uniprot id: A0A8C5LHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

51337:Dlc1
gene id: 51337:Dlc1
uniprot id: A0A8C5KS54
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

51337:Aqp5
gene id: 51337:Aqp5
uniprot id: A0A8C5K812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

51337:Hnrnpul1
gene id: 51337:Hnrnpul1
uniprot id: A0A8C5NXG8
names: Subcellular Location Annotation
messages: Nucleus

51337:Ca2
gene id: 51337:Ca2
uniprot id: A0A8C5K067
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

51337:Ess2
gene id: 51337:Ess2
uniprot id: A0A8C5JWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

51337:Cacng1
gene id: 51337:Cacng1
uniprot id: A0A8C5KZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

51337:Riok2
gene id: 51337:Riok2
uniprot id: A0A8C5KQX7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

51337:Ccnj
gene id: 51337:Ccnj
uniprot id: A0A8C5LF69
names: Similarity
messages: Belongs to the cyclin family.

51337:Barhl2
gene id: 51337:Barhl2
uniprot id: A0A8C5K999
names: Subcellular Location Annotation
messages: Nucleus

51337:Slc66a1
gene id: 51337:Slc66a1
uniprot id: A0A8C5KWR0
names: Subcellular Location Annotation
messages: Membrane

51337:Ercc4
gene id: 51337:Ercc4
uniprot id: A0A8C5K4S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

51337:LOC101595759
gene id: 51337:LOC101595759
uniprot id: A0A8C5LK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:St8sia4
gene id: 51337:St8sia4
uniprot id: A0A8C5KB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Tmem86b
gene id: 51337:Tmem86b
uniprot id: A0A8C5L951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

51337:Tmem18
gene id: 51337:Tmem18
uniprot id: A0A8C5L0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

51337:Wdfy2
gene id: 51337:Wdfy2
uniprot id: A0A8C5KYD5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

51337:Nts
gene id: 51337:Nts
uniprot id: A0A8C5KN63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

51337:Etfb
gene id: 51337:Etfb
uniprot id: A0A8C5K5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

51337:Cldn6
gene id: 51337:Cldn6
uniprot id: A0A8C5JWQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Tprg1
gene id: 51337:Tprg1
uniprot id: A0A8C5K9A8
names: Similarity
messages: Belongs to the TPRG1 family.

51337:Bpgm
gene id: 51337:Bpgm
uniprot id: A0A8C5JYJ6
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

51337:Prrt1
gene id: 51337:Prrt1
uniprot id: A0A8C5L0U4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

51337:Alg5
gene id: 51337:Alg5
uniprot id: A0A8C5LDX0
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

51337:Ptpn1
gene id: 51337:Ptpn1
uniprot id: A0A8C5LKN3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

51337:LOC101616190
gene id: 51337:LOC101616190
uniprot id: A0A8C5K8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

51337:Sema4c
gene id: 51337:Sema4c
uniprot id: A0A8C5L056
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Esrrg
gene id: 51337:Esrrg
uniprot id: A0A8C5NXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

51337:Rtn4ip1
gene id: 51337:Rtn4ip1
uniprot id: A0A8C5KPV4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

51337:LOC101616641
gene id: 51337:LOC101616641
uniprot id: A0A8C5LH64
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

51337:Cpsf7
gene id: 51337:Cpsf7
uniprot id: A0A8C5L586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

51337:Pax2
gene id: 51337:Pax2
uniprot id: A0A8C5JWD5
uniprot id: A0A8C5JZE9
names: Subcellular Location Annotation
messages: Nucleus

51337:Ddi1
gene id: 51337:Ddi1
uniprot id: A0A8C5JYJ0
names: Similarity
messages: Belongs to the DDI1 family.

51337:Dpysl2
gene id: 51337:Dpysl2
uniprot id: A0A8C5LDS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. Interacts with CLN6. Interacts with MICALL1.
messages: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

51337:Nxf1
gene id: 51337:Nxf1
uniprot id: A0A8C5KTV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

51337:Nipal3
gene id: 51337:Nipal3
uniprot id: A0A8C5KMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

51337:Hsph1
gene id: 51337:Hsph1
uniprot id: A0A8C5JWC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

51337:Cdk2ap2
gene id: 51337:Cdk2ap2
uniprot id: A0A8C5KK53
names: Similarity
messages: Belongs to the CDK2AP family.

51337:Isl2
gene id: 51337:Isl2
uniprot id: A0A8C5P277
names: Subcellular Location Annotation
messages: Nucleus

51337:C4H2orf49
gene id: 51337:C4H2orf49
uniprot id: A0A8C5LE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

51337:Prim2
gene id: 51337:Prim2
uniprot id: A0A8C5KSP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

51337:Oaz2
gene id: 51337:Oaz2
uniprot id: A0A8C5LI64
names: Similarity
messages: Belongs to the ODC antizyme family.

51337:LOC101607665
gene id: 51337:LOC101607665
uniprot id: A0A8C5KFW8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-II subfamily.

51337:Ro60
gene id: 51337:Ro60
uniprot id: A0A8C5KZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

51337:Rplp0
gene id: 51337:Rplp0
uniprot id: A0A8C5NYP0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

51337:Best2
gene id: 51337:Best2
uniprot id: A0A8C5P222
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

51337:Tpm2
gene id: 51337:Tpm2
uniprot id: A0A8C5JX91
uniprot id: A0A8C5JXI0
uniprot id: A0A8C5NU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

51337:Cpne6
gene id: 51337:Cpne6
uniprot id: A0A8C5KUF5
names: Similarity
messages: Belongs to the copine family.

51337:Nox3
gene id: 51337:Nox3
uniprot id: A0A8C5L5N5
names: Subcellular Location Annotation
messages: Membrane

51337:Rpl6
gene id: 51337:Rpl6
uniprot id: A0A8C5KVN1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

51337:Smpd1
gene id: 51337:Smpd1
uniprot id: A0A8C5KPM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

51337:Niban2
gene id: 51337:Niban2
uniprot id: A0A8C5LE45
names: Similarity
messages: Belongs to the Niban family.

51337:Baz1b
gene id: 51337:Baz1b
uniprot id: A0A8C5LA49
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101597286
gene id: 51337:LOC101597286
uniprot id: A0A8C5LIM8
uniprot id: A0A8C5LIY1
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Surf4
gene id: 51337:Surf4
uniprot id: A0A8C5K826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

51337:LOC101605741
gene id: 51337:LOC101605741
uniprot id: A0A8C5KBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

51337:LOC101614373
gene id: 51337:LOC101614373
uniprot id: A0A8C5K6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

51337:Cdk11a
gene id: 51337:Cdk11a
uniprot id: A0A8C5KYD6
uniprot id: A0A8C5KZ37
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

51337:Nptx1
gene id: 51337:Nptx1
uniprot id: A0A8C5KRM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Arl6ip5
gene id: 51337:Arl6ip5
uniprot id: A0A8C5LDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

51337:Ints7
gene id: 51337:Ints7
uniprot id: A0A8C5KW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

51337:Kxd1
gene id: 51337:Kxd1
uniprot id: A0A8C5KS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

51337:LOC101611539
gene id: 51337:LOC101611539
uniprot id: A0A8C5NWA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus

51337:Mrrf
gene id: 51337:Mrrf
uniprot id: A0A8C5KGA8
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

51337:Galk1
gene id: 51337:Galk1
uniprot id: A0A8C5KQJ6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

51337:Rpl29
gene id: 51337:Rpl29
uniprot id: A0A8C5L8H0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

51337:Gpr174
gene id: 51337:Gpr174
uniprot id: A0A8C5KL40
names: Subcellular Location Annotation
messages: Membrane

51337:Rpp30
gene id: 51337:Rpp30
uniprot id: A0A8C5L545
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

51337:Nr1d1
gene id: 51337:Nr1d1
uniprot id: A0A8C5LHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Trim46
gene id: 51337:Trim46
uniprot id: A0A8C5L0H6
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Rps11
gene id: 51337:Rps11
uniprot id: A0A8C5L9W9
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

51337:Syn3
gene id: 51337:Syn3
uniprot id: A0A8C5JXC7
names: Similarity
messages: Belongs to the synapsin family.

51337:Arrdc1
gene id: 51337:Arrdc1
uniprot id: A0A8C5KMD9
names: Similarity
messages: Belongs to the arrestin family.

51337:Wdr18
gene id: 51337:Wdr18
uniprot id: A0A8C5KBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148. Interacts with NOL9. Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development.
messages: nucleolus
messages: nucleoplasm

51337:LOC101603924
gene id: 51337:LOC101603924
uniprot id: A0A8C5KFF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

51337:Adk
gene id: 51337:Adk
uniprot id: A0A8C5NU54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

51337:Mdm4
gene id: 51337:Mdm4
uniprot id: A0A8C5KTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

51337:Myh13
gene id: 51337:Myh13
uniprot id: A0A8C5KED4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Pmm1
gene id: 51337:Pmm1
uniprot id: A0A8C5L4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

51337:Plcb3
gene id: 51337:Plcb3
uniprot id: A0A8C5P4X4
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

51337:LOC101598679
gene id: 51337:LOC101598679
uniprot id: A0A8C5K612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tfcp2
gene id: 51337:Tfcp2
uniprot id: A0A8C5L009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

51337:Junb
gene id: 51337:Junb
uniprot id: A0A8C5KHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

51337:Cxcl12
gene id: 51337:Cxcl12
uniprot id: A0A8C5K8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

51337:Sqstm1
gene id: 51337:Sqstm1
uniprot id: A0A8C5KE74
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

51337:Elf5
gene id: 51337:Elf5
uniprot id: A0A8C5NUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Rpn1
gene id: 51337:Rpn1
uniprot id: A0A8C5P0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

51337:Stx8
gene id: 51337:Stx8
uniprot id: A0A8C5KEC5
names: Similarity
messages: Belongs to the syntaxin family.

51337:Ptafr
gene id: 51337:Ptafr
uniprot id: A0A8C5NYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane
messages: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.

51337:Hs3st2
gene id: 51337:Hs3st2
uniprot id: A0A8C5P3J8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:Dhrs11
gene id: 51337:Dhrs11
uniprot id: A0A8C5K439
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Mcoln1
gene id: 51337:Mcoln1
uniprot id: A0A8C5NZ59
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

51337:Pitx2
gene id: 51337:Pitx2
uniprot id: A0A8C5L1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

51337:Ca7
gene id: 51337:Ca7
uniprot id: A0A8C5K8T8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

51337:LOC101609317
gene id: 51337:LOC101609317
uniprot id: A0A8C5LCP6
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

51337:Alad
gene id: 51337:Alad
uniprot id: A0A8C5KKU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

51337:C3H15orf40
gene id: 51337:C3H15orf40
uniprot id: A0A8C5P5Q7
names: Similarity
messages: Belongs to the UPF0235 family.

51337:Carmil2
gene id: 51337:Carmil2
uniprot id: A0A8C5L9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

51337:Sh3rf3
gene id: 51337:Sh3rf3
uniprot id: A0A8C5KPT7
names: Similarity
messages: Belongs to the SH3RF family.

51337:Frg1
gene id: 51337:Frg1
uniprot id: A0A8C5L756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

51337:LOC101610562
gene id: 51337:LOC101610562
uniprot id: A0A8C5K2V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

51337:Tekt4
gene id: 51337:Tekt4
uniprot id: A0A8C5K4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

51337:Plec
gene id: 51337:Plec
uniprot id: A0A8C5KCG0
uniprot id: A0A8C5KCI9
uniprot id: A0A8C5KFA4
uniprot id: A0A8C5KG42
uniprot id: A0A8C5KIJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plakin or cytolinker family.
messages: cytoskeleton

51337:Tnmd
gene id: 51337:Tnmd
uniprot id: A0A8C5KVZ8
names: Similarity
messages: Belongs to the chondromodulin-1 family.

51337:Adamts15
gene id: 51337:Adamts15
uniprot id: A0A8C5K9K6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

51337:Mapkapk3
gene id: 51337:Mapkapk3
uniprot id: A0A8C5JYU7
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Asic4
gene id: 51337:Asic4
uniprot id: A0A8C5KT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

51337:Abt1
gene id: 51337:Abt1
uniprot id: A0A8C5KGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

51337:Cog6
gene id: 51337:Cog6
uniprot id: A0A8C5P492
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

51337:LOC101603055
gene id: 51337:LOC101603055
uniprot id: A0A8C5K2S9
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

51337:Errfi1
gene id: 51337:Errfi1
uniprot id: A0A8C5LBF6
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

51337:Arsj
gene id: 51337:Arsj
uniprot id: A0A8C5P3P7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Angptl4
gene id: 51337:Angptl4
uniprot id: A0A8C5KYM3
names: Subcellular Location Annotation
messages: Secreted

51337:Il17b
gene id: 51337:Il17b
uniprot id: A0A8C5KLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

51337:St6gal2
gene id: 51337:St6gal2
uniprot id: A0A8C5KCF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.

51337:LOC101607003
gene id: 51337:LOC101607003
uniprot id: A0A8C5KJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Gpsm1
gene id: 51337:Gpsm1
uniprot id: A0A8C5LBA5
uniprot id: A0A8C5LHC9
names: Similarity
messages: Belongs to the GPSM family.

51337:Sstr2
gene id: 51337:Sstr2
uniprot id: A0A8C5NVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

51337:Pcyox1l
gene id: 51337:Pcyox1l
uniprot id: A0A8C5NWU6
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

51337:Gpr37l1
gene id: 51337:Gpr37l1
uniprot id: A0A8C5LGE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Cldn23
gene id: 51337:Cldn23
uniprot id: A0A8C5KHC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Rpia
gene id: 51337:Rpia
uniprot id: A0A8C5KI04
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

51337:Emc4
gene id: 51337:Emc4
uniprot id: A0A8C5KHI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Psme2
gene id: 51337:Psme2
uniprot id: A0A8C5K9M6
names: Similarity
messages: Belongs to the PA28 family.

51337:Cpped1
gene id: 51337:Cpped1
uniprot id: A0A8C5L9Y8
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

51337:Msra
gene id: 51337:Msra
uniprot id: A0A8C5KEJ6
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

51337:Tmem163
gene id: 51337:Tmem163
uniprot id: A0A8C5NZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

51337:Trpc4
gene id: 51337:Trpc4
uniprot id: A0A8C5K0J7
uniprot id: A0A8C5NUR2
names: Subcellular Location Annotation
messages: Membrane

51337:Serpinb2
gene id: 51337:Serpinb2
uniprot id: A0A8C5K3G8
names: Similarity
messages: Belongs to the serpin family.

51337:Ghsr
gene id: 51337:Ghsr
uniprot id: A0A8C5L9E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

51337:Gins4
gene id: 51337:Gins4
uniprot id: A0A8C5KNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

51337:Psmb9
gene id: 51337:Psmb9
uniprot id: A0A8C5LHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

51337:Foxd2
gene id: 51337:Foxd2
uniprot id: A0A8C5KLI7
names: Subcellular Location Annotation
messages: Nucleus

51337:Cdkl1
gene id: 51337:Cdkl1
uniprot id: A0A8C5LDN1
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Arv1
gene id: 51337:Arv1
uniprot id: A0A8C5JXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

51337:Cdca8
gene id: 51337:Cdca8
uniprot id: A0A8C5L7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

51337:Rab3gap2
gene id: 51337:Rab3gap2
uniprot id: A0A8C5KC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

51337:B4galt1
gene id: 51337:B4galt1
uniprot id: A0A8C5KSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

51337:Pycr2
gene id: 51337:Pycr2
uniprot id: A0A8C5NZI9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

51337:Cby2
gene id: 51337:Cby2
uniprot id: A0A8C5L299
uniprot id: A0A8C5L2F5
names: Similarity
names: Subunit
messages: Belongs to the chibby family. SPERT subfamily.
messages: Homodimer. Binds to NEK1.

51337:S1pr4
gene id: 51337:S1pr4
uniprot id: A0A8C5JXQ0
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101614086
gene id: 51337:LOC101614086
uniprot id: A0A8C5JX27
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

51337:Smarca1
gene id: 51337:Smarca1
uniprot id: A0A8C5JZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

51337:Yipf3
gene id: 51337:Yipf3
uniprot id: A0A8C5LE01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

51337:Hyal4
gene id: 51337:Hyal4
uniprot id: A0A8C5L4C1
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

51337:Rps12
gene id: 51337:Rps12
uniprot id: A0A8C5K1T8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

51337:Tmem126b
gene id: 51337:Tmem126b
uniprot id: A0A8C5KFL8
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101605548
gene id: 51337:LOC101605548
uniprot id: A0A8C5L1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

51337:F9
gene id: 51337:F9
uniprot id: A0A8C5LCE4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Timm50
gene id: 51337:Timm50
uniprot id: A0A8C5L8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Tpm1
gene id: 51337:Tpm1
uniprot id: A0A8C5LAL3
uniprot id: A0A8C5LF43
uniprot id: A0A8C5LFY0
uniprot id: A0A8C5LHD8
uniprot id: A0A8C5LHE7
uniprot id: A0A8C5P4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

51337:Slc12a5
gene id: 51337:Slc12a5
uniprot id: A0A8C5K7A4
uniprot id: A0A8C5NWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

51337:Bcl2l11
gene id: 51337:Bcl2l11
uniprot id: A0A8C5L6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Bcl-2 family.
messages: Forms heterodimers with a number of antiapoptotic Bcl-2 proteins including MCL1, BCL2, BCL2L1 isoform Bcl-X(L), BCL2A1/BFL-1.
messages: Induces apoptosis and anoikis.

51337:Tmem8b
gene id: 51337:Tmem8b
uniprot id: A0A8C5KJX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

51337:Bhmt
gene id: 51337:Bhmt
uniprot id: A0A8C5LEM3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

51337:Mphosph10
gene id: 51337:Mphosph10
uniprot id: A0A8C5KNA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

51337:Tenm3
gene id: 51337:Tenm3
uniprot id: A0A8C5KAF3
uniprot id: A0A8C5NWK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Copa
gene id: 51337:Copa
uniprot id: A0A8C5P5Q6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

51337:Ccnl1
gene id: 51337:Ccnl1
uniprot id: A0A8C5LHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Nucleus speckle
messages: nucleoplasm

51337:LOC101597781
gene id: 51337:LOC101597781
uniprot id: A0A8C5LA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Slc9a3r1
gene id: 51337:Slc9a3r1
uniprot id: A0A8C5K5S7
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

51337:LOC101603288
gene id: 51337:LOC101603288
uniprot id: A0A8C5K5I4
names: Subunit
messages: Interacts with hair keratins.

51337:Cmpk2
gene id: 51337:Cmpk2
uniprot id: A0A8C5KQ96
names: Similarity
messages: Belongs to the thymidylate kinase family.

51337:Rbm3
gene id: 51337:Rbm3
uniprot id: A0A8C5KHV9
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Psmd2
gene id: 51337:Psmd2
uniprot id: A0A8C5LJI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

51337:LOC101602305
gene id: 51337:LOC101602305
uniprot id: A0A8C5KIN5
names: Subcellular Location Annotation
messages: Nucleus

51337:Tigd3
gene id: 51337:Tigd3
uniprot id: A0A8C5KBC5
names: Subcellular Location Annotation
messages: Nucleus

51337:Pla2g15
gene id: 51337:Pla2g15
uniprot id: A0A8C5KE65
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

51337:Wnt3a
gene id: 51337:Wnt3a
uniprot id: A0A8C5L6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Rspo2
gene id: 51337:Rspo2
uniprot id: A0A8C5NVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

51337:Cacna1d
gene id: 51337:Cacna1d
uniprot id: A0A8C5P550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

51337:Tram1
gene id: 51337:Tram1
uniprot id: A0A8C5L9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

51337:Wnt2
gene id: 51337:Wnt2
uniprot id: A0A8C5KYF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Aprt
gene id: 51337:Aprt
uniprot id: A0A8C5L0F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

51337:Hdac5
gene id: 51337:Hdac5
uniprot id: A0A8C5LAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

51337:Tdo2
gene id: 51337:Tdo2
uniprot id: A0A8C5KUP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Nit1
gene id: 51337:Nit1
uniprot id: A0A8C5NU56
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

51337:Six1
gene id: 51337:Six1
uniprot id: A0A8C5K8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

51337:Trip10
gene id: 51337:Trip10
uniprot id: A0A8C5KD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

51337:Sv2c
gene id: 51337:Sv2c
uniprot id: A0A8C5KF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

51337:Kpna4
gene id: 51337:Kpna4
uniprot id: A0A8C5L0B5
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

51337:Awat2
gene id: 51337:Awat2
uniprot id: A0A8C5KEG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

51337:Psmd3
gene id: 51337:Psmd3
uniprot id: A0A8C5P4R3
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

51337:Lcor
gene id: 51337:Lcor
uniprot id: A0A8C5KCY6
names: Subcellular Location Annotation
messages: Nucleus

51337:Acss3
gene id: 51337:Acss3
uniprot id: A0A8C5K5D0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Neurod6
gene id: 51337:Neurod6
uniprot id: A0A8C5L237
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

51337:LOC101617512
gene id: 51337:LOC101617512
uniprot id: A0A8C5K0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

51337:Tmed1
gene id: 51337:Tmed1
uniprot id: A0A8C5L0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

51337:Axl
gene id: 51337:Axl
uniprot id: A0A8C5KB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

51337:Pdk4
gene id: 51337:Pdk4
uniprot id: A0A8C5K468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

51337:Kdsr
gene id: 51337:Kdsr
uniprot id: A0A8C5LAK1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Gpr15
gene id: 51337:Gpr15
uniprot id: A0A8C5NYS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Nlgn2
gene id: 51337:Nlgn2
uniprot id: A0A8C5L9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

51337:Ski
gene id: 51337:Ski
uniprot id: A0A8C5L950
names: Similarity
messages: Belongs to the SKI family.

51337:Ago1
gene id: 51337:Ago1
uniprot id: A0A8C5L0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

51337:LOC101595472
gene id: 51337:LOC101595472
uniprot id: A0A8C5KJM6
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Adhfe1
gene id: 51337:Adhfe1
uniprot id: A0A8C5K9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

51337:Haao
gene id: 51337:Haao
uniprot id: A0A8C5KCV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

51337:Stxbp2
gene id: 51337:Stxbp2
uniprot id: A0A8C5P5K7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

51337:Kcnt1
gene id: 51337:Kcnt1
uniprot id: A0A8C5K1X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Tmc4
gene id: 51337:Tmc4
uniprot id: A0A8C5KTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

51337:Mapk8ip3
gene id: 51337:Mapk8ip3
uniprot id: A0A8C5KEE1
uniprot id: A0A8C5NXL5
names: Similarity
messages: Belongs to the JIP scaffold family.

51337:Ptgdr
gene id: 51337:Ptgdr
uniprot id: A0A8C5KXY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Ilk
gene id: 51337:Ilk
uniprot id: A0A8C5KZD2
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

51337:Ca14
gene id: 51337:Ca14
uniprot id: A0A8C5LBC0
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

51337:Nphs2
gene id: 51337:Nphs2
uniprot id: A0A8C5KPY7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

51337:Cldn11
gene id: 51337:Cldn11
uniprot id: A0A8C5LFN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Sptbn2
gene id: 51337:Sptbn2
uniprot id: A0A8C5K6J8
names: Similarity
messages: Belongs to the spectrin family.

51337:Dhodh
gene id: 51337:Dhodh
uniprot id: A0A8C5K123
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

51337:Snapin
gene id: 51337:Snapin
uniprot id: A0A8C5K7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

51337:Syt2
gene id: 51337:Syt2
uniprot id: A0A8C5K6N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

51337:Esrp2
gene id: 51337:Esrp2
uniprot id: A0A8C5JZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

51337:Pola2
gene id: 51337:Pola2
uniprot id: A0A8C5KKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

51337:Slc2a8
gene id: 51337:Slc2a8
uniprot id: A0A8C5KAQ6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

51337:Abitram
gene id: 51337:Abitram
uniprot id: A0A8C5LKA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

51337:Tspan5
gene id: 51337:Tspan5
uniprot id: A0A8C5P1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Impa2
gene id: 51337:Impa2
uniprot id: A0A8C5LIK4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

51337:Il24
gene id: 51337:Il24
uniprot id: A0A8C5L4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

51337:Crabp2
gene id: 51337:Crabp2
uniprot id: A0A8C5KLZ8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:Gpkow
gene id: 51337:Gpkow
uniprot id: A0A8C5KLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

51337:Nap1l4
gene id: 51337:Nap1l4
uniprot id: A0A8C5JZS5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

51337:Acap1
gene id: 51337:Acap1
uniprot id: A0A8C5NU61
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

51337:Fam91a1
gene id: 51337:Fam91a1
uniprot id: A0A8C5P1Q1
names: Similarity
messages: Belongs to the FAM91 family.

51337:Cdx4
gene id: 51337:Cdx4
uniprot id: A0A8C5KQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

51337:Sostdc1
gene id: 51337:Sostdc1
uniprot id: A0A8C5K7W9
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Lss
gene id: 51337:Lss
uniprot id: A0A8C5K659
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

51337:Oaz1
gene id: 51337:Oaz1
uniprot id: A0A8C5K0W8
names: Similarity
messages: Belongs to the ODC antizyme family.

51337:Snap25
gene id: 51337:Snap25
uniprot id: A0A8C5KER4
uniprot id: A0A8C5NXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: perinuclear region
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

51337:Hmx2
gene id: 51337:Hmx2
uniprot id: A0A8C5L6T3
names: Subcellular Location Annotation
messages: Nucleus

51337:Hk2
gene id: 51337:Hk2
uniprot id: A0A8C5LH32
names: Similarity
messages: Belongs to the hexokinase family.

51337:Rps26
gene id: 51337:Rps26
uniprot id: A0A8C5L9D6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

51337:Penk
gene id: 51337:Penk
uniprot id: A0A8C5KAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Increases glutamate release in the striatum and decreases GABA concentration in the striatum.
messages: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Secreted
messages: chromaffin granule lumen

51337:Actg2
gene id: 51337:Actg2
uniprot id: A0A8C5LCF3
names: Similarity
messages: Belongs to the actin family.

51337:Dctn2
gene id: 51337:Dctn2
uniprot id: A0A8C5K114
names: Function
names: Similarity
messages: Belongs to the dynactin subunit 2 family.
messages: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

51337:Mitf
gene id: 51337:Mitf
uniprot id: A0A8C5L178
uniprot id: A0A8C5P1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

51337:Mctp1
gene id: 51337:Mctp1
uniprot id: A0A8C5K682
names: Subcellular Location Annotation
messages: Membrane

51337:C3
gene id: 51337:C3
uniprot id: A0A8C5LMZ4
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

51337:Naga
gene id: 51337:Naga
uniprot id: A0A8C5LEM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

51337:Acap3
gene id: 51337:Acap3
uniprot id: A0A8C5L803
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

51337:Kif4a
gene id: 51337:Kif4a
uniprot id: A0A8C5NU10
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Ipo9
gene id: 51337:Ipo9
uniprot id: A0A8C5KGK6
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Itgb4
gene id: 51337:Itgb4
uniprot id: A0A8C5KZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

51337:Nalf2
gene id: 51337:Nalf2
uniprot id: A0A8C5KRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

51337:Cdr2l
gene id: 51337:Cdr2l
uniprot id: A0A8C5K185
names: Similarity
messages: Belongs to the CDR2 family.

51337:Ovca2
gene id: 51337:Ovca2
uniprot id: A0A8C5KU31
names: Similarity
messages: Belongs to the LovG family.

51337:Bckdk
gene id: 51337:Bckdk
uniprot id: A0A8C5KXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

51337:Ndrg4
gene id: 51337:Ndrg4
uniprot id: A0A8C5KR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

51337:LOC101616965
gene id: 51337:LOC101616965
uniprot id: A0A8C5KLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Nucleus

51337:LOC101608698
gene id: 51337:LOC101608698
uniprot id: A0A8C5KPK8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

51337:Lck
gene id: 51337:Lck
uniprot id: A0A8C5L7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

51337:Ccn1
gene id: 51337:Ccn1
uniprot id: A0A8C5L1J2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Galnt5
gene id: 51337:Galnt5
uniprot id: A0A8C5K429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Cfl1
gene id: 51337:Cfl1
uniprot id: A0A8C5LG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: lamellipodium membrane
messages: ruffle membrane

51337:Doc2b
gene id: 51337:Doc2b
uniprot id: A0A8C5P174
names: Subcellular Location Annotation
messages: Membrane

51337:Tssk1b
gene id: 51337:Tssk1b
uniprot id: A0A8C5KH65
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Slc17a6
gene id: 51337:Slc17a6
uniprot id: A0A8C5L5K3
names: Subcellular Location Annotation
messages: Membrane

51337:Chrna4
gene id: 51337:Chrna4
uniprot id: A0A8C5L1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Cdc5l
gene id: 51337:Cdc5l
uniprot id: A0A8C5KCC4
names: Similarity
messages: Belongs to the CEF1 family.

51337:Sap130
gene id: 51337:Sap130
uniprot id: A0A8C5KVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

51337:Nploc4
gene id: 51337:Nploc4
uniprot id: A0A8C5P1P1
names: Similarity
messages: Belongs to the NPL4 family.

51337:Ubac2
gene id: 51337:Ubac2
uniprot id: A0A8C5LDE3
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101595676
gene id: 51337:LOC101595676
uniprot id: A0A8C5L5R0
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Clic5
gene id: 51337:Clic5
uniprot id: A0A8C5KZ65
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

51337:Hgs
gene id: 51337:Hgs
uniprot id: A0A8C5KVC6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
messages: multivesicular body membrane

51337:LOC101595489
gene id: 51337:LOC101595489
uniprot id: A0A8C5NYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystatin family.
messages: Secreted

51337:Camsap2
gene id: 51337:Camsap2
uniprot id: A0A8C5L424
uniprot id: A0A8C5L7M6
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

51337:Idh1
gene id: 51337:Idh1
uniprot id: A0A8C5L000
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

51337:St8sia1
gene id: 51337:St8sia1
uniprot id: A0A8C5L257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Ccr4
gene id: 51337:Ccr4
uniprot id: A0A8C5K2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Ccny
gene id: 51337:Ccny
uniprot id: A0A8C5KW73
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

51337:Nefl
gene id: 51337:Nefl
uniprot id: A0A8C5KAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: cytoskeleton

51337:Bcr
gene id: 51337:Bcr
uniprot id: A0A8C5KAH8
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

51337:Fmn1
gene id: 51337:Fmn1
uniprot id: A0A8C5NY20
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

51337:Pdgfd
gene id: 51337:Pdgfd
uniprot id: A0A8C5LAU0
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101599463
gene id: 51337:LOC101599463
uniprot id: A0A8C5L9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intermediate filament family.
messages: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
messages: Interacts with SYNM.
messages: axon

51337:LOC101602440
gene id: 51337:LOC101602440
uniprot id: A0A8C5NZK2
names: Similarity
messages: Belongs to the pro/parathymosin family.

51337:Shox2
gene id: 51337:Shox2
uniprot id: A0A8C5KKN4
names: Subcellular Location Annotation
messages: Nucleus

51337:Ppp2r5b
gene id: 51337:Ppp2r5b
uniprot id: A0A8C5KG00
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

51337:Kcnd3
gene id: 51337:Kcnd3
uniprot id: A0A8C5LEI0
uniprot id: A0A8C5LHN0
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

51337:C5H3orf70
gene id: 51337:C5H3orf70
uniprot id: A0A8C5KYM1
names: Similarity
messages: Belongs to the UPF0524 family.

51337:Pdc
gene id: 51337:Pdc
uniprot id: A0A8C5P1C5
names: Similarity
messages: Belongs to the phosducin family.

51337:Uros
gene id: 51337:Uros
uniprot id: A0A8C5JZT6
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

51337:Pou5f1
gene id: 51337:Pou5f1
uniprot id: A0A8C5K2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

51337:Brinp3
gene id: 51337:Brinp3
uniprot id: A0A8C5KIN3
names: Similarity
messages: Belongs to the BRINP family.

51337:LOC101609850
gene id: 51337:LOC101609850
uniprot id: A0A8C5LBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

51337:Cct8
gene id: 51337:Cct8
uniprot id: A0A8C5LM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

51337:LOC101601766
gene id: 51337:LOC101601766
uniprot id: A0A8C5K085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101610729
gene id: 51337:LOC101610729
uniprot id: A0A8C5NV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Polr2j
gene id: 51337:Polr2j
uniprot id: A0A8C5KHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

51337:Phex
gene id: 51337:Phex
uniprot id: A0A8C5KNY2
names: Subcellular Location Annotation
messages: Membrane

51337:Aif1l
gene id: 51337:Aif1l
uniprot id: A0A8C5KPW8
names: Subcellular Location Annotation
messages: ruffle membrane

51337:Nsun2
gene id: 51337:Nsun2
uniprot id: A0A8C5KHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

51337:Nxph1
gene id: 51337:Nxph1
uniprot id: A0A8C5P342
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

51337:Ptch2
gene id: 51337:Ptch2
uniprot id: A0A8C5K546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

51337:Ap3m1
gene id: 51337:Ap3m1
uniprot id: A0A8C5L530
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

51337:Snx3
gene id: 51337:Snx3
uniprot id: A0A8C5P481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

51337:Cdk6
gene id: 51337:Cdk6
uniprot id: A0A8C5K6D3
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Map4k3
gene id: 51337:Map4k3
uniprot id: A0A8C5LA48
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

51337:F2rl3
gene id: 51337:F2rl3
uniprot id: A0A8C5NW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Tgm2
gene id: 51337:Tgm2
uniprot id: A0A8C5NVB9
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

51337:Tmem121
gene id: 51337:Tmem121
uniprot id: A0A8C5KMR4
names: Similarity
messages: Belongs to the TMEM121 family.

51337:Foxo4
gene id: 51337:Foxo4
uniprot id: A0A8C5KKH4
names: Subcellular Location Annotation
messages: Nucleus

51337:Ddit4
gene id: 51337:Ddit4
uniprot id: A0A8C5L607
names: Similarity
messages: Belongs to the DDIT4 family.

51337:Sdr9c7
gene id: 51337:Sdr9c7
uniprot id: A0A8C5KK01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Gucy2f
gene id: 51337:Gucy2f
uniprot id: A0A8C5KIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

51337:Msn
gene id: 51337:Msn
uniprot id: A0A8C5P1Y2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

51337:LOC101606345
gene id: 51337:LOC101606345
uniprot id: A0A8C5JZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

51337:LOC101608404
gene id: 51337:LOC101608404
uniprot id: A0A8C5P1L6
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

51337:Elp2
gene id: 51337:Elp2
uniprot id: A0A8C5KG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

51337:Tubb
gene id: 51337:Tubb
uniprot id: A0A8C5LKQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Snrnp27
gene id: 51337:Snrnp27
uniprot id: A0A8C5LEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

51337:Rapsn
gene id: 51337:Rapsn
uniprot id: A0A8C5L7U6
names: Similarity
messages: Belongs to the RAPsyn family.

51337:Adcyap1
gene id: 51337:Adcyap1
uniprot id: A0A8C5LNT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucagon family.
messages: Interacts with ADCYAP1R1 (via N-terminal extracellular domain).
messages: Secreted

51337:Tmem88
gene id: 51337:Tmem88
uniprot id: A0A8C5KJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

51337:C1H9orf116
gene id: 51337:C1H9orf116
uniprot id: A0A8C5LJ61
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

51337:B4galnt4
gene id: 51337:B4galnt4
uniprot id: A0A8C5KTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

51337:Ing1
gene id: 51337:Ing1
uniprot id: A0A8C5KVP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

51337:Atp1b1
gene id: 51337:Atp1b1
uniprot id: A0A8C5KVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Involved in cell adhesion and establishing epithelial cell polarity.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.
messages: sarcolemma

51337:LOC101595945
gene id: 51337:LOC101595945
uniprot id: A0A8C5KYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: extracellular matrix

51337:Inpp4a
gene id: 51337:Inpp4a
uniprot id: A0A8C5KEK2
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

51337:Slc1a6
gene id: 51337:Slc1a6
uniprot id: A0A8C5K475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

51337:Cfb
gene id: 51337:Cfb
uniprot id: A0A8C5L8P6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:LOC105943593
gene id: 51337:LOC105943593
uniprot id: A0A8C5KJI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Nxt1
gene id: 51337:Nxt1
uniprot id: A0A8C5KDT8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

51337:Stk32b
gene id: 51337:Stk32b
uniprot id: A0A8C5KHE1
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Atp6v1h
gene id: 51337:Atp6v1h
uniprot id: A0A8C5KWQ4
uniprot id: A0A8C5L0F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Jph1
gene id: 51337:Jph1
uniprot id: A0A8C5KNF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

51337:Ppp2r5d
gene id: 51337:Ppp2r5d
uniprot id: A0A8C5K8K6
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

51337:Cfap53
gene id: 51337:Cfap53
uniprot id: A0A8C5P4Y1
names: Similarity
messages: Belongs to the CFAP53 family.

51337:Tspan14
gene id: 51337:Tspan14
uniprot id: A0A8C5LIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Olfm2
gene id: 51337:Olfm2
uniprot id: A0A8C5K2S5
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

51337:Tonsl
gene id: 51337:Tonsl
uniprot id: A0A8C5KJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

51337:Adamts5
gene id: 51337:Adamts5
uniprot id: A0A8C5KXM0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

51337:Ncln
gene id: 51337:Ncln
uniprot id: A0A8C5JZU8
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

51337:Rab32
gene id: 51337:Rab32
uniprot id: A0A8C5NZL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

51337:LOC101606524
gene id: 51337:LOC101606524
uniprot id: A0A8C5KDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Dnase1l2
gene id: 51337:Dnase1l2
uniprot id: A0A8C5L2X0
names: Similarity
messages: Belongs to the DNase I family.

51337:Ddx3x
gene id: 51337:Ddx3x
uniprot id: A0A8C5L6A4
names: Similarity
messages: Belongs to the DEAD box helicase family.

51337:Clic2
gene id: 51337:Clic2
uniprot id: A0A8C5P0R4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

51337:Fam25a
gene id: 51337:Fam25a
uniprot id: A0A8C5KMG1
names: Similarity
messages: Belongs to the FAM25 family.

51337:Slc26a4
gene id: 51337:Slc26a4
uniprot id: A0A8C5LA44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

51337:Skil
gene id: 51337:Skil
uniprot id: A0A8C5LJ02
names: Similarity
messages: Belongs to the SKI family.

51337:LOC101603453
gene id: 51337:LOC101603453
uniprot id: A0A8C5K0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Bloc1s6
gene id: 51337:Bloc1s6
uniprot id: A0A8C5LET4
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

51337:Bax
gene id: 51337:Bax
uniprot id: A0A8C5L2U1
names: Similarity
messages: Belongs to the Bcl-2 family.

51337:Tfap2d
gene id: 51337:Tfap2d
uniprot id: A0A8C5KIE9
names: Similarity
messages: Belongs to the AP-2 family.

51337:Sf1
gene id: 51337:Sf1
uniprot id: A0A8C5NXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

51337:Cited4
gene id: 51337:Cited4
uniprot id: A0A8C5JY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

51337:Sesn1
gene id: 51337:Sesn1
uniprot id: A0A8C5KSE4
uniprot id: A0A8C5KTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

51337:Arpc2
gene id: 51337:Arpc2
uniprot id: A0A8C5L0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

51337:Urm1
gene id: 51337:Urm1
uniprot id: A0A8C5KNP1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm

51337:Vil1
gene id: 51337:Vil1
uniprot id: A0A8C5KS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

51337:Magoh
gene id: 51337:Magoh
uniprot id: A0A8C5KP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

51337:LOC101597060
gene id: 51337:LOC101597060
uniprot id: A0A8C5KV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Stat3
gene id: 51337:Stat3
uniprot id: A0A8C5LGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

51337:Amz1
gene id: 51337:Amz1
uniprot id: A0A8C5P299
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

51337:Dusp1
gene id: 51337:Dusp1
uniprot id: A0A8C5K582
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

51337:Dync1li2
gene id: 51337:Dync1li2
uniprot id: A0A8C5KNT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

51337:Atp6v1f
gene id: 51337:Atp6v1f
uniprot id: A0A8C5LHZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Med19
gene id: 51337:Med19
uniprot id: A0A8C5LEG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

51337:Thop1
gene id: 51337:Thop1
uniprot id: A0A8C5K874
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

51337:Aebp1
gene id: 51337:Aebp1
uniprot id: A0A8C5K4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

51337:Hbm
gene id: 51337:Hbm
uniprot id: A0A8C5LIF5
names: Similarity
messages: Belongs to the globin family.

51337:Lyg2
gene id: 51337:Lyg2
uniprot id: A0A8C5K362
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

51337:Polm
gene id: 51337:Polm
uniprot id: A0A8C5NVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

51337:Kcnj14
gene id: 51337:Kcnj14
uniprot id: A0A8C5K3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

51337:Rpl37
gene id: 51337:Rpl37
uniprot id: A0A8C5KPT6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

51337:Acox1
gene id: 51337:Acox1
uniprot id: A0A8C5KSG5
uniprot id: A0A8C5NZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

51337:Suv39h1
gene id: 51337:Suv39h1
uniprot id: A0A8C5KDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

51337:G6pc3
gene id: 51337:G6pc3
uniprot id: A0A8C5KZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

51337:L1cam
gene id: 51337:L1cam
uniprot id: A0A8C5L8I2
uniprot id: A0A8C5LD19
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

51337:Ppif
gene id: 51337:Ppif
uniprot id: A0A8C5KFZ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

51337:Tmem38a
gene id: 51337:Tmem38a
uniprot id: A0A8C5KKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

51337:Ca8
gene id: 51337:Ca8
uniprot id: A0A8C5JTG5
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

51337:Pigm
gene id: 51337:Pigm
uniprot id: A0A8C5KHT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

51337:Hook1
gene id: 51337:Hook1
uniprot id: A0A8C5L243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

51337:Pc
gene id: 51337:Pc
uniprot id: A0A8C5KYX0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

51337:Kmt5c
gene id: 51337:Kmt5c
uniprot id: A0A8C5NUC7
names: Subcellular Location Annotation
messages: Nucleus

51337:Tor2a
gene id: 51337:Tor2a
uniprot id: A0A8C5L937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

51337:Fam168b
gene id: 51337:Fam168b
uniprot id: A0A8C5JWZ8
names: Similarity
messages: Belongs to the FAM168 family.

51337:Gstm3
gene id: 51337:Gstm3
uniprot id: A0A8C5KM49
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

51337:Kcnk6
gene id: 51337:Kcnk6
uniprot id: A0A8C5JXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

51337:Ralb
gene id: 51337:Ralb
uniprot id: A0A8C5P1H4
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

51337:Slc5a12
gene id: 51337:Slc5a12
uniprot id: A0A8C5KPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:Arhgdia
gene id: 51337:Arhgdia
uniprot id: A0A8C5KMJ3
names: Similarity
messages: Belongs to the Rho GDI family.

51337:Sfrp2
gene id: 51337:Sfrp2
uniprot id: A0A8C5KQJ4
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Trdmt1
gene id: 51337:Trdmt1
uniprot id: A0A8C5JVS2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

51337:Ust
gene id: 51337:Ust
uniprot id: A0A8C5L4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

51337:Kcnn1
gene id: 51337:Kcnn1
uniprot id: A0A8C5L8Z1
names: Subcellular Location Annotation
messages: Membrane

51337:Galnt7
gene id: 51337:Galnt7
uniprot id: A0A8C5KPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Fadd
gene id: 51337:Fadd
uniprot id: A0A8C5KJQ3
names: Function
messages: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

51337:Pmvk
gene id: 51337:Pmvk
uniprot id: A0A8C5KKW0
names: Subcellular Location Annotation
messages: cytosol

51337:Grik1
gene id: 51337:Grik1
uniprot id: A0A8C5KW03
uniprot id: A0A8C5L167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Txlna
gene id: 51337:Txlna
uniprot id: A0A8C5K508
names: Similarity
messages: Belongs to the taxilin family.

51337:Gck
gene id: 51337:Gck
uniprot id: A0A8C5L9D9
names: Similarity
messages: Belongs to the hexokinase family.

51337:Cldn17
gene id: 51337:Cldn17
uniprot id: A0A8C5KCH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:C19H1orf52
gene id: 51337:C19H1orf52
uniprot id: A0A8C5KF84
names: Similarity
messages: Belongs to the UPF0690 family.

51337:Tinag
gene id: 51337:Tinag
uniprot id: A0A8C5K6W7
names: Similarity
messages: Belongs to the peptidase C1 family.

51337:Chd2
gene id: 51337:Chd2
uniprot id: A0A8C5JUQ4
names: Subcellular Location Annotation
messages: Nucleus

51337:Htra3
gene id: 51337:Htra3
uniprot id: A0A8C5P4L0
names: Similarity
messages: Belongs to the peptidase S1C family.

51337:Smarcal1
gene id: 51337:Smarcal1
uniprot id: A0A8C5KUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

51337:Rfx3
gene id: 51337:Rfx3
uniprot id: A0A8C5NWE4
names: Subcellular Location Annotation
messages: Nucleus

51337:Nprl2
gene id: 51337:Nprl2
uniprot id: A0A8C5KQW5
names: Similarity
messages: Belongs to the NPR2 family.

51337:Gphb5
gene id: 51337:Gphb5
uniprot id: A0A8C5NYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

51337:Nap1l2
gene id: 51337:Nap1l2
uniprot id: A0A8C5K4V9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

51337:Faim2
gene id: 51337:Faim2
uniprot id: A0A8C5NY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

51337:Tada2b
gene id: 51337:Tada2b
uniprot id: A0A8C5KZM0
names: Subcellular Location Annotation
messages: Nucleus

51337:Frrs1
gene id: 51337:Frrs1
uniprot id: A0A8C5P4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

51337:Ppdpf
gene id: 51337:Ppdpf
uniprot id: A0A8C5P315
names: Similarity
messages: Belongs to the PPDPF family.

51337:Adi1
gene id: 51337:Adi1
uniprot id: A0A8C5KLU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer. Interacts with MMP14.
messages: Nucleus

51337:LOC101600189
gene id: 51337:LOC101600189
uniprot id: A0A8C5KC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

51337:Hpcal4
gene id: 51337:Hpcal4
uniprot id: A0A8C5LM40
names: Function
messages: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.

51337:Stk40
gene id: 51337:Stk40
uniprot id: A0A8C5KKN6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

51337:Dock11
gene id: 51337:Dock11
uniprot id: A0A8C5KFM5
names: Similarity
messages: Belongs to the DOCK family.

51337:Tacr1
gene id: 51337:Tacr1
uniprot id: A0A8C5NWB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

51337:Lta4h
gene id: 51337:Lta4h
uniprot id: A0A8C5KEI4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

51337:LOC101595424
gene id: 51337:LOC101595424
uniprot id: A0A8C5K2J6
names: Similarity
messages: Belongs to the fructosamine kinase family.

51337:Vac14
gene id: 51337:Vac14
uniprot id: A0A8C5JWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

51337:Hspa2
gene id: 51337:Hspa2
uniprot id: A0A8C5JX97
names: Similarity
messages: Belongs to the heat shock protein 70 family.

51337:Npas4
gene id: 51337:Npas4
uniprot id: A0A8C5L944
names: Subcellular Location Annotation
messages: Nucleus

51337:Calhm5
gene id: 51337:Calhm5
uniprot id: A0A8C5JUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

51337:Fgf7
gene id: 51337:Fgf7
uniprot id: A0A8C5NWG5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Slc16a2
gene id: 51337:Slc16a2
uniprot id: A0A8C5K3P8
names: Subcellular Location Annotation
messages: Membrane

51337:Emg1
gene id: 51337:Emg1
uniprot id: A0A8C5L148
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

51337:Hexim2
gene id: 51337:Hexim2
uniprot id: A0A8C5L119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

51337:Get4
gene id: 51337:Get4
uniprot id: A0A8C5KFP3
names: Similarity
messages: Belongs to the GET4 family.

51337:Ccdc124
gene id: 51337:Ccdc124
uniprot id: A0A8C5L4I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

51337:Pou4f3
gene id: 51337:Pou4f3
uniprot id: A0A8C5JYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

51337:LOC101596668
gene id: 51337:LOC101596668
uniprot id: A0A8C5KEU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome

51337:Decr2
gene id: 51337:Decr2
uniprot id: A0A8C5KJC1
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

51337:C15H18orf21
gene id: 51337:C15H18orf21
uniprot id: A0A8C5KGN1
names: Similarity
messages: Belongs to the UPF0711 family.

51337:Serpini2
gene id: 51337:Serpini2
uniprot id: A0A8C5L427
names: Similarity
messages: Belongs to the serpin family.

51337:Dync2h1
gene id: 51337:Dync2h1
uniprot id: A0A8C5JXM8
uniprot id: A0A8C5JZH5
names: Similarity
messages: Belongs to the dynein heavy chain family.

51337:LOC101596688
gene id: 51337:LOC101596688
uniprot id: A0A8C5KBF4
names: Similarity
messages: Belongs to the FAM136 family.

51337:Rpn2
gene id: 51337:Rpn2
uniprot id: A0A8C5KX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

51337:LOC101597523
gene id: 51337:LOC101597523
uniprot id: A0A8C5NU63
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

51337:Slitrk1
gene id: 51337:Slitrk1
uniprot id: A0A8C5K1I8
names: Similarity
messages: Belongs to the SLITRK family.

51337:Ppp1cc
gene id: 51337:Ppp1cc
uniprot id: A0A8C5L1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Midbody
messages: microtubule organizing center
messages: nucleolus
messages: nucleoplasm

51337:Tars2
gene id: 51337:Tars2
uniprot id: A0A8C5L9M8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

51337:LOC101614084
gene id: 51337:LOC101614084
uniprot id: A0A8C5KFY8
names: Similarity
messages: Belongs to the CWC15 family.

51337:LOC101596570
gene id: 51337:LOC101596570
uniprot id: A0A8C5P5H5
names: Similarity
messages: Belongs to the globin family.

51337:Paxbp1
gene id: 51337:Paxbp1
uniprot id: A0A8C5K1X0
names: Similarity
messages: Belongs to the GCF family.

51337:Plp2
gene id: 51337:Plp2
uniprot id: A0A8C5KCT8
names: Subcellular Location Annotation
messages: Membrane

51337:Kpnb1
gene id: 51337:Kpnb1
uniprot id: A0A8C5KDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

51337:S100g
gene id: 51337:S100g
uniprot id: A0A8C5L083
names: Similarity
messages: Belongs to the S-100 family.

51337:Gpr6
gene id: 51337:Gpr6
uniprot id: A0A8C5NYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Med23
gene id: 51337:Med23
uniprot id: A0A8C5KIU6
uniprot id: A0A8C5KKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

51337:Serpinb8
gene id: 51337:Serpinb8
uniprot id: A0A8C5LLZ6
names: Similarity
messages: Belongs to the serpin family.

51337:LOC101608175
gene id: 51337:LOC101608175
uniprot id: A0A8C5KL71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

51337:Pcyt1a
gene id: 51337:Pcyt1a
uniprot id: A0A8C5K8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
messages: Endoplasmic reticulum

51337:Olfml2b
gene id: 51337:Olfml2b
uniprot id: A0A8C5K5J4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Gngt2
gene id: 51337:Gngt2
uniprot id: A0A8C5JZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:Slc39a1
gene id: 51337:Slc39a1
uniprot id: A0A8C5LBA7
names: Subcellular Location Annotation
messages: Membrane

51337:Pspc1
gene id: 51337:Pspc1
uniprot id: A0A8C5L3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

51337:Wnt9a
gene id: 51337:Wnt9a
uniprot id: A0A8C5P3W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:LOC101601568
gene id: 51337:LOC101601568
uniprot id: A0A8C5KPB2
names: Subcellular Location Annotation
messages: Secreted

51337:Triap1
gene id: 51337:Triap1
uniprot id: A0A8C5KY43
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

51337:Cand2
gene id: 51337:Cand2
uniprot id: A0A8C5L0E8
names: Similarity
messages: Belongs to the CAND family.

51337:Sars2
gene id: 51337:Sars2
uniprot id: A0A8C5KZG1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

51337:Akr1a1
gene id: 51337:Akr1a1
uniprot id: A0A8C5KHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

51337:Gps1
gene id: 51337:Gps1
uniprot id: A0A8C5JZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

51337:Spty2d1
gene id: 51337:Spty2d1
uniprot id: A0A8C5K3L2
names: Similarity
messages: Belongs to the SPT2 family.

51337:Actr5
gene id: 51337:Actr5
uniprot id: A0A8C5JXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

51337:Slc35a2
gene id: 51337:Slc35a2
uniprot id: A0A8C5KTN3
uniprot id: A0A8C5P1C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

51337:LOC101603525
gene id: 51337:LOC101603525
uniprot id: A0A8C5P089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

51337:Rbbp5
gene id: 51337:Rbbp5
uniprot id: A0A8C5L8A7
names: Subcellular Location Annotation
messages: Nucleus

51337:Scnn1g
gene id: 51337:Scnn1g
uniprot id: A0A8C5KEG2
names: Subcellular Location Annotation
messages: Membrane

51337:Alg12
gene id: 51337:Alg12
uniprot id: A0A8C5LEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Banf2
gene id: 51337:Banf2
uniprot id: A0A8C5KI25
names: Subcellular Location Annotation
messages: Nucleus

51337:Dcc
gene id: 51337:Dcc
uniprot id: A0A8C5NVD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

51337:Gimd1
gene id: 51337:Gimd1
uniprot id: A0A8C5P1M9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

51337:Celsr2
gene id: 51337:Celsr2
uniprot id: A0A8C5LHA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

51337:Slc35f1
gene id: 51337:Slc35f1
uniprot id: A0A8C5P068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

51337:Lef1
gene id: 51337:Lef1
uniprot id: A0A8C5KSY3
uniprot id: A0A8C5KT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

51337:Mal
gene id: 51337:Mal
uniprot id: A0A8C5LKS7
names: Subcellular Location Annotation
messages: Membrane

51337:Pdzk1ip1
gene id: 51337:Pdzk1ip1
uniprot id: A0A8C5KK96
names: Subcellular Location Annotation
messages: Membrane

51337:Tmem35a
gene id: 51337:Tmem35a
uniprot id: A0A8C5K9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

51337:Gpr61
gene id: 51337:Gpr61
uniprot id: A0A8C5K3G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Asb8
gene id: 51337:Asb8
uniprot id: A0A8C5LJ48
names: Function
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

51337:Myf5
gene id: 51337:Myf5
uniprot id: A0A8C5K2Y1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

51337:Mmp21
gene id: 51337:Mmp21
uniprot id: A0A8C5L1T5
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:Ido1
gene id: 51337:Ido1
uniprot id: A0A8C5NXS3
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

51337:Psmd12
gene id: 51337:Psmd12
uniprot id: A0A8C5KX30
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

51337:Tgfbr1
gene id: 51337:Tgfbr1
uniprot id: A0A8C5K5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

51337:LOC101612754
gene id: 51337:LOC101612754
uniprot id: A0A8C5NWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

51337:Heatr5b
gene id: 51337:Heatr5b
uniprot id: A0A8C5P0E5
names: Similarity
messages: Belongs to the HEATR5 family.

51337:Nrf1
gene id: 51337:Nrf1
uniprot id: A0A8C5K1V4
uniprot id: A0A8C5K595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

51337:Snx30
gene id: 51337:Snx30
uniprot id: A0A8C5L0F9
names: Similarity
messages: Belongs to the sorting nexin family.

51337:Hnrnpdl
gene id: 51337:Hnrnpdl
uniprot id: A0A8C5LCW2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Clrn3
gene id: 51337:Clrn3
uniprot id: A0A8C5L3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

51337:Mrpl10
gene id: 51337:Mrpl10
uniprot id: A0A8C5K4F5
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

51337:Fah
gene id: 51337:Fah
uniprot id: A0A8C5LGH0
names: Similarity
messages: Belongs to the FAH family.

51337:Mrpl27
gene id: 51337:Mrpl27
uniprot id: A0A8C5K0W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

51337:Lpar1
gene id: 51337:Lpar1
uniprot id: A0A8C5KVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

51337:Ndufb4
gene id: 51337:Ndufb4
uniprot id: A0A8C5NUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Htr1f
gene id: 51337:Htr1f
uniprot id: A0A8C5KHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

51337:Evx1
gene id: 51337:Evx1
uniprot id: A0A8C5LFQ3
names: Subcellular Location Annotation
messages: Nucleus

51337:Hs3st3b1
gene id: 51337:Hs3st3b1
uniprot id: A0A8C5K895
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:Rgs2
gene id: 51337:Rgs2
uniprot id: A0A8C5L431
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: nucleolus

51337:Cplx3
gene id: 51337:Cplx3
uniprot id: A0A8C5K3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

51337:Chst11
gene id: 51337:Chst11
uniprot id: A0A8C5L4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Rcl1
gene id: 51337:Rcl1
uniprot id: A0A8C5LHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

51337:Atp6v0d1
gene id: 51337:Atp6v0d1
uniprot id: A0A8C5L7B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:LOC101595687
gene id: 51337:LOC101595687
uniprot id: A0A8C5NYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Banf1
gene id: 51337:Banf1
uniprot id: A0A8C5JZU7
names: Subcellular Location Annotation
messages: Nucleus

51337:Nsfl1c
gene id: 51337:Nsfl1c
uniprot id: A0A8C5L0A1
uniprot id: A0A8C5P2R3
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.

51337:Kcna6
gene id: 51337:Kcna6
uniprot id: A0A8C5KND8
names: Subcellular Location Annotation
messages: Membrane

51337:Yipf5
gene id: 51337:Yipf5
uniprot id: A0A8C5NUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

51337:Baiap2
gene id: 51337:Baiap2
uniprot id: A0A8C5P014
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

51337:LOC101604801
gene id: 51337:LOC101604801
uniprot id: A0A8C5KBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:S1pr2
gene id: 51337:S1pr2
uniprot id: A0A8C5KI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Fscn1
gene id: 51337:Fscn1
uniprot id: A0A8C5L118
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

51337:Borcs7
gene id: 51337:Borcs7
uniprot id: A0A8C5L2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

51337:Lypd6
gene id: 51337:Lypd6
uniprot id: A0A8C5L2R7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Pias2
gene id: 51337:Pias2
uniprot id: A0A8C5LBN7
names: Similarity
messages: Belongs to the PIAS family.

51337:Acvrl1
gene id: 51337:Acvrl1
uniprot id: A0A8C5KJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

51337:Psph
gene id: 51337:Psph
uniprot id: A0A8C5KL33
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

51337:Notch1
gene id: 51337:Notch1
uniprot id: A0A8C5JXT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

51337:Slc27a3
gene id: 51337:Slc27a3
uniprot id: A0A8C5LNR1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Mmp23b
gene id: 51337:Mmp23b
uniprot id: A0A8C5LBR5
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101612453
gene id: 51337:LOC101612453
uniprot id: A0A8C5K876
names: Similarity
messages: Belongs to the TACO1 family.

51337:Sema3c
gene id: 51337:Sema3c
uniprot id: A0A8C5KXY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Ocln
gene id: 51337:Ocln
uniprot id: A0A8C5L996
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

51337:LOC101607270
gene id: 51337:LOC101607270
uniprot id: A0A8C5K0K8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Gde1
gene id: 51337:Gde1
uniprot id: A0A8C5L8R8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

51337:Clvs1
gene id: 51337:Clvs1
uniprot id: A0A8C5KKM3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

51337:Atp10d
gene id: 51337:Atp10d
uniprot id: A0A8C5KDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

51337:Gda
gene id: 51337:Gda
uniprot id: A0A8C5KXK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

51337:LOC101606396
gene id: 51337:LOC101606396
uniprot id: A0A8C5KB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

51337:Ucp1
gene id: 51337:Ucp1
uniprot id: A0A8C5L3B3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: May undergo ubiquitin-mediated proteasomal degradation.
messages: Membrane
messages: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
messages: Mitochondrion inner membrane

51337:Rps28
gene id: 51337:Rps28
uniprot id: A0A8C5KU70
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS28 family.
messages: Component of the 40S small ribosomal subunit.

51337:Lrrc8a
gene id: 51337:Lrrc8a
uniprot id: A0A8C5JTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

51337:Polr3k
gene id: 51337:Polr3k
uniprot id: A0A8C5P4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

51337:Apaf1
gene id: 51337:Apaf1
uniprot id: A0A8C5KPM9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

51337:Sema3f
gene id: 51337:Sema3f
uniprot id: A0A8C5LK62
uniprot id: A0A8C5P622
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101596172
gene id: 51337:LOC101596172
uniprot id: A0A8C5KUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

51337:Timp1
gene id: 51337:Timp1
uniprot id: A0A8C5JX71
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

51337:Barhl1
gene id: 51337:Barhl1
uniprot id: A0A8C5KBU4
names: Subcellular Location Annotation
messages: Nucleus

51337:Hikeshi
gene id: 51337:Hikeshi
uniprot id: A0A8C5KF24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

51337:Acvr2b
gene id: 51337:Acvr2b
uniprot id: A0A8C5KTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

51337:Dynlt2b
gene id: 51337:Dynlt2b
uniprot id: A0A8C5KXA2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

51337:Rtn1
gene id: 51337:Rtn1
uniprot id: A0A8C5K2E8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101605828
gene id: 51337:LOC101605828
uniprot id: A0A8C5KMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

51337:Gfra1
gene id: 51337:Gfra1
uniprot id: A0A8C5KYI2
uniprot id: A0A8C5L0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

51337:Hoxa1
gene id: 51337:Hoxa1
uniprot id: A0A8C5LGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

51337:Fermt3
gene id: 51337:Fermt3
uniprot id: A0A8C5KU65
names: Similarity
messages: Belongs to the kindlin family.

51337:LOC101594411
gene id: 51337:LOC101594411
uniprot id: A0A8C5KF14
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

51337:Slc2a2
gene id: 51337:Slc2a2
uniprot id: A0A8C5LES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

51337:Cd9
gene id: 51337:Cd9
uniprot id: A0A8C5LH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

51337:Mgst2
gene id: 51337:Mgst2
uniprot id: A0A8C5K8Y2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

51337:Dgat2l6
gene id: 51337:Dgat2l6
uniprot id: A0A8C5NW67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101593531
gene id: 51337:LOC101593531
uniprot id: A0A8C5KSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane

51337:Actn3
gene id: 51337:Actn3
uniprot id: A0A8C5KKB8
names: Similarity
messages: Belongs to the alpha-actinin family.

51337:Rgs1
gene id: 51337:Rgs1
uniprot id: A0A8C5LBI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

51337:Actr3b
gene id: 51337:Actr3b
uniprot id: A0A8C5L1X0
names: Similarity
messages: Belongs to the actin family.

51337:Atp6v1g1
gene id: 51337:Atp6v1g1
uniprot id: A0A8C5KRB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Cnn3
gene id: 51337:Cnn3
uniprot id: A0A8C5KAG5
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

51337:LOC101606398
gene id: 51337:LOC101606398
uniprot id: A0A8C5JX48
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

51337:Epha7
gene id: 51337:Epha7
uniprot id: A0A8C5KRU1
names: Subcellular Location Annotation
messages: Membrane

51337:Gsdma
gene id: 51337:Gsdma
uniprot id: A0A8C5K068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

51337:Crx
gene id: 51337:Crx
uniprot id: A0A8C5KKQ5
names: Subcellular Location Annotation
messages: Nucleus

51337:Ppl
gene id: 51337:Ppl
uniprot id: A0A8C5LB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plakin or cytolinker family.
messages: cytoskeleton

51337:Tfe3
gene id: 51337:Tfe3
uniprot id: A0A8C5KWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

51337:Nrp2
gene id: 51337:Nrp2
uniprot id: A0A8C5KUN5
uniprot id: A0A8C5P0N9
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101595017
gene id: 51337:LOC101595017
uniprot id: A0A8C5KCA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Six2
gene id: 51337:Six2
uniprot id: A0A8C5K7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

51337:Drd3
gene id: 51337:Drd3
uniprot id: A0A8C5P1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
messages: Membrane

51337:Chrna10
gene id: 51337:Chrna10
uniprot id: A0A8C5KQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Vars1
gene id: 51337:Vars1
uniprot id: A0A8C5L205
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Tfeb
gene id: 51337:Tfeb
uniprot id: A0A8C5K1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

51337:Nudt21
gene id: 51337:Nudt21
uniprot id: A0A8C5P0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

51337:Ppp5c
gene id: 51337:Ppp5c
uniprot id: A0A8C5KNH7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

51337:Pjvk
gene id: 51337:Pjvk
uniprot id: A0A8C5KHM2
names: Similarity
messages: Belongs to the gasdermin family.

51337:Arap3
gene id: 51337:Arap3
uniprot id: A0A8C5KJR0
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Spp2
gene id: 51337:Spp2
uniprot id: A0A8C5L241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

51337:Alg2
gene id: 51337:Alg2
uniprot id: A0A8C5K1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

51337:Slc9a6
gene id: 51337:Slc9a6
uniprot id: A0A8C5KQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

51337:Gsk3a
gene id: 51337:Gsk3a
uniprot id: A0A8C5JV08
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

51337:Gna15
gene id: 51337:Gna15
uniprot id: A0A8C5KKY8
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

51337:Gcg
gene id: 51337:Gcg
uniprot id: A0A8C5KU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

51337:Cfap299
gene id: 51337:Cfap299
uniprot id: A0A8C5L3A4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

51337:Flnb
gene id: 51337:Flnb
uniprot id: A0A8C5L489
names: Similarity
messages: Belongs to the filamin family.

51337:Ctso
gene id: 51337:Ctso
uniprot id: A0A8C5L0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

51337:Nog
gene id: 51337:Nog
uniprot id: A0A8C5KLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

51337:Ap1m1
gene id: 51337:Ap1m1
uniprot id: A0A8C5K1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

51337:Ubiad1
gene id: 51337:Ubiad1
uniprot id: A0A8C5K053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

51337:Otub2
gene id: 51337:Otub2
uniprot id: A0A8C5KY63
names: Similarity
messages: Belongs to the peptidase C65 family.

51337:Psmb6
gene id: 51337:Psmb6
uniprot id: A0A8C5KLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

51337:Setd2
gene id: 51337:Setd2
uniprot id: A0A8C5LEA5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

51337:Ubl3
gene id: 51337:Ubl3
uniprot id: A0A8C5KPS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Bicd1
gene id: 51337:Bicd1
uniprot id: A0A8C5NV90
names: Similarity
messages: Belongs to the BicD family.

51337:Creg1
gene id: 51337:Creg1
uniprot id: A0A8C5JX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

51337:Leprot
gene id: 51337:Leprot
uniprot id: A0A8C5LII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

51337:Slc12a4
gene id: 51337:Slc12a4
uniprot id: A0A8C5KN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

51337:Xrn2
gene id: 51337:Xrn2
uniprot id: A0A8C5LEZ7
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

51337:Kcnk1
gene id: 51337:Kcnk1
uniprot id: A0A8C5KYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

51337:Spa17
gene id: 51337:Spa17
uniprot id: A0A8C5LA95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

51337:Eri1
gene id: 51337:Eri1
uniprot id: A0A8C5KNV1
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Sf3b3
gene id: 51337:Sf3b3
uniprot id: A0A8C5JZI4
names: Subcellular Location Annotation
messages: Nucleus

51337:Cckbr
gene id: 51337:Cckbr
uniprot id: A0A8C5LI56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

51337:Arl3
gene id: 51337:Arl3
uniprot id: A0A8C5JW65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

51337:LOC101606939
gene id: 51337:LOC101606939
uniprot id: A0A8C5L846
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Eif2b2
gene id: 51337:Eif2b2
uniprot id: A0A8C5KNP2
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

51337:Adck5
gene id: 51337:Adck5
uniprot id: A0A8C5KJ50
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

51337:Mrap2
gene id: 51337:Mrap2
uniprot id: A0A8C5KIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Prph2
gene id: 51337:Prph2
uniprot id: A0A8C5KMH7
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

51337:Tas1r3
gene id: 51337:Tas1r3
uniprot id: A0A8C5L0S0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Rassf1
gene id: 51337:Rassf1
uniprot id: A0A8C5L538
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Gins2
gene id: 51337:Gins2
uniprot id: A0A8C5P3D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

51337:Ffar2
gene id: 51337:Ffar2
uniprot id: A0A8C5K5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Cdc42bpb
gene id: 51337:Cdc42bpb
uniprot id: A0A8C5P496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

51337:Hcrt
gene id: 51337:Hcrt
uniprot id: A0A8C5LDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Synapse
messages: Vesicle

51337:Srm
gene id: 51337:Srm
uniprot id: A0A8C5KC35
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

51337:Igf2bp1
gene id: 51337:Igf2bp1
uniprot id: A0A8C5JYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

51337:Yipf2
gene id: 51337:Yipf2
uniprot id: A0A8C5K8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

51337:Cand1
gene id: 51337:Cand1
uniprot id: A0A8C5KZS6
names: Similarity
messages: Belongs to the CAND family.

51337:Tspan8
gene id: 51337:Tspan8
uniprot id: A0A8C5KS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Hk3
gene id: 51337:Hk3
uniprot id: A0A8C5KED8
names: Similarity
messages: Belongs to the hexokinase family.

51337:Ccl21
gene id: 51337:Ccl21
uniprot id: A0A8C5LE50
names: Subcellular Location Annotation
messages: Secreted

51337:LOC101607450
gene id: 51337:LOC101607450
uniprot id: A0A8C5K0B0
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

51337:Pias1
gene id: 51337:Pias1
uniprot id: A0A8C5P320
names: Similarity
messages: Belongs to the PIAS family.

51337:Got1
gene id: 51337:Got1
uniprot id: A0A8C5P2M3
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

51337:Csnk2a1
gene id: 51337:Csnk2a1
uniprot id: A0A8C5NY86
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Pigc
gene id: 51337:Pigc
uniprot id: A0A8C5K8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

51337:Pax7
gene id: 51337:Pax7
uniprot id: A0A8C5KBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

51337:Ubald1
gene id: 51337:Ubald1
uniprot id: A0A8C5K1F4
names: Similarity
messages: Belongs to the UBALD family.

51337:Spin4
gene id: 51337:Spin4
uniprot id: A0A8C5NVU8
names: Similarity
messages: Belongs to the SPIN/STSY family.

51337:LOC101610984
gene id: 51337:LOC101610984
uniprot id: A0A8C5KBH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Nme4
gene id: 51337:Nme4
uniprot id: A0A8C5LGF3
names: Similarity
messages: Belongs to the NDK family.

51337:Aldh1b1
gene id: 51337:Aldh1b1
uniprot id: A0A8C5JZX0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

51337:Ston1
gene id: 51337:Ston1
uniprot id: A0A8C5KWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

51337:H1-1
gene id: 51337:H1-1
uniprot id: A0A8C5KI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

51337:LOC101598790
gene id: 51337:LOC101598790
uniprot id: A0A8C5KZP4
names: Subcellular Location Annotation
messages: Membrane

51337:Ebpl
gene id: 51337:Ebpl
uniprot id: A0A8C5KQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Zgpat
gene id: 51337:Zgpat
uniprot id: A0A8C5KY96
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

51337:Stx6
gene id: 51337:Stx6
uniprot id: A0A8C5L5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

51337:Rpf1
gene id: 51337:Rpf1
uniprot id: A0A8C5L5N2
names: Subcellular Location Annotation
messages: nucleolus

51337:Thtpa
gene id: 51337:Thtpa
uniprot id: A0A8C5LE08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

51337:Adora3
gene id: 51337:Adora3
uniprot id: A0A8C5L1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

51337:Znf408
gene id: 51337:Znf408
uniprot id: A0A8C5KSN2
names: Subcellular Location Annotation
messages: Nucleus

51337:Sgsh
gene id: 51337:Sgsh
uniprot id: A0A8C5KY27
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Peli3
gene id: 51337:Peli3
uniprot id: A0A8C5NX25
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

51337:Kdelr1
gene id: 51337:Kdelr1
uniprot id: A0A8C5K658
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Eno4
gene id: 51337:Eno4
uniprot id: A0A8C5KID1
names: Similarity
messages: Belongs to the enolase family.

51337:Tbx6
gene id: 51337:Tbx6
uniprot id: A0A8C5L4L9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Atp2b2
gene id: 51337:Atp2b2
uniprot id: A0A8C5K4C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Pclaf
gene id: 51337:Pclaf
uniprot id: A0A8C5K8D5
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

51337:Tmem167b
gene id: 51337:Tmem167b
uniprot id: A0A8C5KDI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Disp3
gene id: 51337:Disp3
uniprot id: A0A8C5KQD7
names: Subcellular Location Annotation
messages: Membrane

51337:F2rl2
gene id: 51337:F2rl2
uniprot id: A0A8C5L6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Thbs3
gene id: 51337:Thbs3
uniprot id: A0A8C5K8E5
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Spock1
gene id: 51337:Spock1
uniprot id: A0A8C5K6P3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Has2
gene id: 51337:Has2
uniprot id: A0A8C5JWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

51337:Gria4
gene id: 51337:Gria4
uniprot id: A0A8C5L260
uniprot id: A0A8C5L3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Entpd7
gene id: 51337:Entpd7
uniprot id: A0A8C5KPB9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

51337:Otub1
gene id: 51337:Otub1
uniprot id: A0A8C5P131
names: Similarity
messages: Belongs to the peptidase C65 family.

51337:Sepsecs
gene id: 51337:Sepsecs
uniprot id: A0A8C5JZ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

51337:Zc3h15
gene id: 51337:Zc3h15
uniprot id: A0A8C5L699
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

51337:Mars1
gene id: 51337:Mars1
uniprot id: A0A8C5L1F8
uniprot id: A0A8C5P216
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Hoxb8
gene id: 51337:Hoxb8
uniprot id: A0A8C5K0L2
names: Subcellular Location Annotation
messages: Nucleus

51337:Cntnap1
gene id: 51337:Cntnap1
uniprot id: A0A8C5K1U5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

51337:Porcn
gene id: 51337:Porcn
uniprot id: A0A8C5KE40
uniprot id: A0A8C5KIA1
uniprot id: A0A8C5NYQ1
names: Subcellular Location Annotation
messages: Membrane

51337:Smarcb1
gene id: 51337:Smarcb1
uniprot id: A0A8C5K5Z6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

51337:Adck1
gene id: 51337:Adck1
uniprot id: A0A8C5P0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

51337:Insig2
gene id: 51337:Insig2
uniprot id: A0A8C5LGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

51337:Znf532
gene id: 51337:Znf532
uniprot id: A0A8C5K6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

51337:Arl2
gene id: 51337:Arl2
uniprot id: A0A8C5L4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

51337:Marcksl1
gene id: 51337:Marcksl1
uniprot id: A0A8C5L9H6
names: Similarity
messages: Belongs to the MARCKS family.

51337:Itm2c
gene id: 51337:Itm2c
uniprot id: A0A8C5NZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

51337:Hs2st1
gene id: 51337:Hs2st1
uniprot id: A0A8C5JXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

51337:Amigo2
gene id: 51337:Amigo2
uniprot id: A0A8C5KWT1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

51337:Trappc1
gene id: 51337:Trappc1
uniprot id: A0A8C5JW58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

51337:Dvl3
gene id: 51337:Dvl3
uniprot id: A0A8C5KCA1
names: Similarity
messages: Belongs to the DSH family.

51337:Gnat3
gene id: 51337:Gnat3
uniprot id: A0A8C5K1U1
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

51337:Arid3a
gene id: 51337:Arid3a
uniprot id: A0A8C5KKU8
names: Subcellular Location Annotation
messages: Nucleus

51337:Pdlim3
gene id: 51337:Pdlim3
uniprot id: A0A8C5LH45
names: Subcellular Location Annotation
messages: Z line

51337:Nkx6-3
gene id: 51337:Nkx6-3
uniprot id: A0A8C5KCB2
names: Subcellular Location Annotation
messages: Nucleus

51337:Mrps18b
gene id: 51337:Mrps18b
uniprot id: A0A8C5NUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

51337:LOC101600275
gene id: 51337:LOC101600275
uniprot id: A0A8C5KJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Sema3b
gene id: 51337:Sema3b
uniprot id: A0A8C5K852
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101593354
gene id: 51337:LOC101593354
uniprot id: A0A8C5K2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

51337:Atp2c2
gene id: 51337:Atp2c2
uniprot id: A0A8C5JXF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Uts2
gene id: 51337:Uts2
uniprot id: A0A8C5KRE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

51337:Acta1
gene id: 51337:Acta1
uniprot id: A0A8C5P2E0
names: Similarity
messages: Belongs to the actin family.

51337:Cdx2
gene id: 51337:Cdx2
uniprot id: A0A8C5K862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

51337:Snrpb
gene id: 51337:Snrpb
uniprot id: A0A8C5LKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

51337:Max
gene id: 51337:Max
uniprot id: A0A8C5L3L5
uniprot id: A0A8C5L7U9
names: Similarity
messages: Belongs to the MAX family.

51337:Irak1bp1
gene id: 51337:Irak1bp1
uniprot id: A0A8C5L6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

51337:Mical2
gene id: 51337:Mical2
uniprot id: A0A8C5L7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

51337:Piwil1
gene id: 51337:Piwil1
uniprot id: A0A8C5LF87
names: Similarity
messages: Belongs to the argonaute family.

51337:S100a1
gene id: 51337:S100a1
uniprot id: A0A8C5KVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Mitochondrion

51337:Tssk2
gene id: 51337:Tssk2
uniprot id: A0A8C5KGP5
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Unk
gene id: 51337:Unk
uniprot id: A0A8C5K7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

51337:Impdh2
gene id: 51337:Impdh2
uniprot id: A0A8C5P517
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

51337:Fhl5
gene id: 51337:Fhl5
uniprot id: A0A8C5NU87
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

51337:Qrfpr
gene id: 51337:Qrfpr
uniprot id: A0A8C5L0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Dgkg
gene id: 51337:Dgkg
uniprot id: A0A8C5JZ11
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

51337:Vangl2
gene id: 51337:Vangl2
uniprot id: A0A8C5L3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

51337:LOC101601628
gene id: 51337:LOC101601628
uniprot id: A0A8C5KIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Dis3
gene id: 51337:Dis3
uniprot id: A0A8C5KFY7
names: Similarity
messages: Belongs to the RNR ribonuclease family.

51337:Glce
gene id: 51337:Glce
uniprot id: A0A8C5KVQ2
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

51337:Runx2
gene id: 51337:Runx2
uniprot id: A0A8C5P381
names: Subcellular Location Annotation
messages: Nucleus

51337:Mon2
gene id: 51337:Mon2
uniprot id: A0A8C5KLT2
uniprot id: A0A8C5KMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON2 family.
messages: Membrane

51337:Fscn3
gene id: 51337:Fscn3
uniprot id: A0A8C5KET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

51337:Hyal2
gene id: 51337:Hyal2
uniprot id: A0A8C5LB78
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

51337:Nat10
gene id: 51337:Nat10
uniprot id: A0A8C5LJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

51337:Ap3s1
gene id: 51337:Ap3s1
uniprot id: A0A8C5KA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

51337:Pnrc2
gene id: 51337:Pnrc2
uniprot id: A0A8C5K2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

51337:S100a6
gene id: 51337:S100a6
uniprot id: A0A8C5JTQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
messages: Nucleus envelope

51337:Bmpr2
gene id: 51337:Bmpr2
uniprot id: A0A8C5KRU8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

51337:LOC101599996
gene id: 51337:LOC101599996
uniprot id: A0A8C5KGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Nsg2
gene id: 51337:Nsg2
uniprot id: A0A8C5L7L0
names: Similarity
messages: Belongs to the NSG family.

51337:Pdcd11
gene id: 51337:Pdcd11
uniprot id: A0A8C5KQQ3
names: Subcellular Location Annotation
messages: nucleolus

51337:Actr3
gene id: 51337:Actr3
uniprot id: A0A8C5K7T4
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

51337:Snx2
gene id: 51337:Snx2
uniprot id: A0A8C5K636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

51337:LOC101605551
gene id: 51337:LOC101605551
uniprot id: A0A8C5LD41
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ADAM1/fertilin subunit alpha.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

51337:Lyzl4
gene id: 51337:Lyzl4
uniprot id: A0A8C5JZN7
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

51337:Mdh2
gene id: 51337:Mdh2
uniprot id: A0A8C5KVT6
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

51337:Arsa
gene id: 51337:Arsa
uniprot id: A0A8C5K5S3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Lrrc14
gene id: 51337:Lrrc14
uniprot id: A0A8C5KJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRAME family. LRRC14 subfamily.
messages: Cytoplasm

51337:Mocs3
gene id: 51337:Mocs3
uniprot id: A0A8C5JYD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Interacts with NFS1.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

51337:Nr4a1
gene id: 51337:Nr4a1
uniprot id: A0A8C5KXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: Cytoplasm
messages: Nucleus

51337:LOC105944455
gene id: 51337:LOC105944455
uniprot id: A0A8C5L811
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

51337:Srpra
gene id: 51337:Srpra
uniprot id: A0A8C5L5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

51337:Psmd13
gene id: 51337:Psmd13
uniprot id: A0A8C5KCT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

51337:Sox14
gene id: 51337:Sox14
uniprot id: A0A8C5KC94
names: Subcellular Location Annotation
messages: Nucleus

51337:Stk32a
gene id: 51337:Stk32a
uniprot id: A0A8C5JZA3
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Pgap3
gene id: 51337:Pgap3
uniprot id: A0A8C5P4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

51337:Khdrbs2
gene id: 51337:Khdrbs2
uniprot id: A0A8C5KYP0
names: Similarity
messages: Belongs to the KHDRBS family.

51337:LOC101609069
gene id: 51337:LOC101609069
uniprot id: A0A8C5K4I8
names: Similarity
messages: Belongs to the IAP family.

51337:Snrnp200
gene id: 51337:Snrnp200
uniprot id: A0A8C5P5S4
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

51337:Pttg1
gene id: 51337:Pttg1
uniprot id: A0A8C5LH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

51337:Hmx3
gene id: 51337:Hmx3
uniprot id: A0A8C5KX38
names: Subcellular Location Annotation
messages: Nucleus

51337:Tmem184a
gene id: 51337:Tmem184a
uniprot id: A0A8C5LJJ8
names: Subcellular Location Annotation
messages: Membrane

51337:Mpo
gene id: 51337:Mpo
uniprot id: A0A8C5LAK8
names: Cofactor
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group covalently per monomer.

51337:Dusp6
gene id: 51337:Dusp6
uniprot id: A0A8C5K286
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

51337:Pepd
gene id: 51337:Pepd
uniprot id: A0A8C5KWE1
names: Similarity
messages: Belongs to the peptidase M24B family.

51337:Wrnip1
gene id: 51337:Wrnip1
uniprot id: A0A8C5NXF9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

51337:Pygb
gene id: 51337:Pygb
uniprot id: A0A8C5LFN9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

51337:Vps52
gene id: 51337:Vps52
uniprot id: A0A8C5LCA5
names: Similarity
messages: Belongs to the VPS52 family.

51337:Foxp3
gene id: 51337:Foxp3
uniprot id: A0A8C5KYD4
names: Subcellular Location Annotation
messages: Nucleus

51337:Prm2
gene id: 51337:Prm2
uniprot id: A0A8C5KFL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protamine P2 family.
messages: Interacts with TDRP.
messages: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

51337:Dlx2
gene id: 51337:Dlx2
uniprot id: A0A8C5L4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

51337:LOC101610664
gene id: 51337:LOC101610664
uniprot id: A0A8C5KDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

51337:Fam219a
gene id: 51337:Fam219a
uniprot id: A0A8C5K5J1
names: Similarity
messages: Belongs to the FAM219 family.

51337:Sez6l2
gene id: 51337:Sez6l2
uniprot id: A0A8C5K8B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Kcna7
gene id: 51337:Kcna7
uniprot id: A0A8C5K1M7
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101601478
gene id: 51337:LOC101601478
uniprot id: A0A8C5KEW7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Spata20
gene id: 51337:Spata20
uniprot id: A0A8C5K3M1
names: Function
names: Subcellular Location Annotation
messages: May play a role in fertility regulation.
messages: Secreted

51337:Mdk
gene id: 51337:Mdk
uniprot id: A0A8C5LJ78
names: Similarity
messages: Belongs to the pleiotrophin family.

51337:Lsm1
gene id: 51337:Lsm1
uniprot id: A0A8C5NZ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

51337:Cap1
gene id: 51337:Cap1
uniprot id: A0A8C5P469
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

51337:Ecrg4
gene id: 51337:Ecrg4
uniprot id: A0A8C5LJC5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

51337:Osbpl6
gene id: 51337:Osbpl6
uniprot id: A0A8C5KTY8
uniprot id: A0A8C5KVU0
names: Similarity
messages: Belongs to the OSBP family.

51337:Znf830
gene id: 51337:Znf830
uniprot id: A0A8C5K8Z4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

51337:Chrna2
gene id: 51337:Chrna2
uniprot id: A0A8C5L0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:P4hb
gene id: 51337:P4hb
uniprot id: A0A8C5KJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

51337:Dipk2a
gene id: 51337:Dipk2a
uniprot id: A0A8C5NW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

51337:Alg10
gene id: 51337:Alg10
uniprot id: A0A8C5L606
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Mesd
gene id: 51337:Mesd
uniprot id: A0A8C5L1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

51337:Rnf2
gene id: 51337:Rnf2
uniprot id: A0A8C5NXD5
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

51337:Ddx41
gene id: 51337:Ddx41
uniprot id: A0A8C5K6Y1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

51337:Gnpda1
gene id: 51337:Gnpda1
uniprot id: A0A8C5L8X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

51337:Adamts2
gene id: 51337:Adamts2
uniprot id: A0A8C5JZE3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

51337:Derl1
gene id: 51337:Derl1
uniprot id: A0A8C5NWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

51337:Map3k7
gene id: 51337:Map3k7
uniprot id: A0A8C5L6P1
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

51337:Nipal1
gene id: 51337:Nipal1
uniprot id: A0A8C5K250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

51337:Dhtkd1
gene id: 51337:Dhtkd1
uniprot id: A0A8C5LJS4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

51337:LOC101609122
gene id: 51337:LOC101609122
uniprot id: A0A8C5K7U6
names: Subcellular Location Annotation
messages: Membrane

51337:Agpat3
gene id: 51337:Agpat3
uniprot id: A0A8C5P328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

51337:Amdhd1
gene id: 51337:Amdhd1
uniprot id: A0A8C5K8V7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

51337:LOC101600527
gene id: 51337:LOC101600527
uniprot id: A0A8C5NV56
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

51337:Top3b
gene id: 51337:Top3b
uniprot id: A0A8C5L2V1
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

51337:LOC101597562
gene id: 51337:LOC101597562
uniprot id: A0A8C5KDA0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

51337:Neil3
gene id: 51337:Neil3
uniprot id: A0A8C5L854
names: Similarity
messages: Belongs to the FPG family.

51337:Hnrnpul2
gene id: 51337:Hnrnpul2
uniprot id: A0A8C5KEM8
names: Subcellular Location Annotation
messages: Nucleus

51337:Atp6v0e1
gene id: 51337:Atp6v0e1
uniprot id: A0A8C5P1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Tp53inp2
gene id: 51337:Tp53inp2
uniprot id: A0A8C5P2C4
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

51337:Ube4a
gene id: 51337:Ube4a
uniprot id: A0A8C5P252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

51337:Synpr
gene id: 51337:Synpr
uniprot id: A0A8C5KP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

51337:Rap2b
gene id: 51337:Rap2b
uniprot id: A0A8C5K811
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

51337:Tmsb10
gene id: 51337:Tmsb10
uniprot id: A0A8C5K0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

51337:Agap1
gene id: 51337:Agap1
uniprot id: A0A8C5KFJ5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

51337:Cav1
gene id: 51337:Cav1
uniprot id: A0A8C5L7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

51337:Ccser2
gene id: 51337:Ccser2
uniprot id: A0A8C5K4A6
names: Similarity
messages: Belongs to the CCSER family.

51337:LOC101602359
gene id: 51337:LOC101602359
uniprot id: A0A8C5NYF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Atad1
gene id: 51337:Atad1
uniprot id: A0A8C5K3Q2
names: Similarity
messages: Belongs to the AAA ATPase family.

51337:Nell2
gene id: 51337:Nell2
uniprot id: A0A8C5K632
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Pex19
gene id: 51337:Pex19
uniprot id: A0A8C5LAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

51337:Dusp7
gene id: 51337:Dusp7
uniprot id: A0A8C5LE69
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

51337:Gjd4
gene id: 51337:Gjd4
uniprot id: A0A8C5KRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Ttyh1
gene id: 51337:Ttyh1
uniprot id: A0A8C5NXB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable chloride channel.

51337:Acsl1
gene id: 51337:Acsl1
uniprot id: A0A8C5KAE4
uniprot id: A0A8C5KCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane

51337:Fam53b
gene id: 51337:Fam53b
uniprot id: A0A8C5KRG6
names: Similarity
messages: Belongs to the FAM53 family.

51337:Ext1
gene id: 51337:Ext1
uniprot id: A0A8C5P324
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Forms a homo/heterooligomeric complex with EXT2. Interacts with NDST1.
messages: Membrane
messages: cis-Golgi network membrane

51337:Mbtps2
gene id: 51337:Mbtps2
uniprot id: A0A8C5KYS1
names: Similarity
messages: Belongs to the peptidase M50A family.

51337:Hsp90ab1
gene id: 51337:Hsp90ab1
uniprot id: A0A8C5L1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

51337:Sost
gene id: 51337:Sost
uniprot id: A0A8C5KTY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

51337:Crat
gene id: 51337:Crat
uniprot id: A0A8C5LCM5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

51337:Vipr2
gene id: 51337:Vipr2
uniprot id: A0A8C5KPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

51337:LOC101617823
gene id: 51337:LOC101617823
uniprot id: A0A8C5K5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

51337:Hs6st1
gene id: 51337:Hs6st1
uniprot id: A0A8C5LFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

51337:Creb3l2
gene id: 51337:Creb3l2
uniprot id: A0A8C5L9N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

51337:Tmem147
gene id: 51337:Tmem147
uniprot id: A0A8C5KYJ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Cercam
gene id: 51337:Cercam
uniprot id: A0A8C5NYI3
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

51337:Mef2d
gene id: 51337:Mef2d
uniprot id: A0A8C5KGM5
names: Subcellular Location Annotation
messages: Nucleus

51337:Fip1l1
gene id: 51337:Fip1l1
uniprot id: A0A8C5KMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

51337:Mpl
gene id: 51337:Mpl
uniprot id: A0A8C5LF33
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

51337:Ptma
gene id: 51337:Ptma
uniprot id: A0A8C5KQZ5
names: Similarity
messages: Belongs to the pro/parathymosin family.

51337:Ddx43
gene id: 51337:Ddx43
uniprot id: A0A8C5KL47
names: Similarity
messages: Belongs to the DEAD box helicase family.

51337:Itih1
gene id: 51337:Itih1
uniprot id: A0A8C5L2Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

51337:Rpl17
gene id: 51337:Rpl17
uniprot id: A0A8C5L0G3
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

51337:Unc93a
gene id: 51337:Unc93a
uniprot id: A0A8C5NXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

51337:Fos
gene id: 51337:Fos
uniprot id: A0A8C5K500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Fos subfamily.
messages: cytosol

51337:LOC101604216
gene id: 51337:LOC101604216
uniprot id: A0A8C5K2F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

51337:LOC101612471
gene id: 51337:LOC101612471
uniprot id: A0A8C5KI37
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Cct3
gene id: 51337:Cct3
uniprot id: A0A8C5KHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

51337:Tspan2
gene id: 51337:Tspan2
uniprot id: A0A8C5K045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Hgfac
gene id: 51337:Hgfac
uniprot id: A0A8C5KUJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Psmb10
gene id: 51337:Psmb10
uniprot id: A0A8C5P551
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

51337:Inka1
gene id: 51337:Inka1
uniprot id: A0A8C5KDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

51337:Ankrd13b
gene id: 51337:Ankrd13b
uniprot id: A0A8C5KBW5
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

51337:Pign
gene id: 51337:Pign
uniprot id: A0A8C5K6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

51337:Pfdn6
gene id: 51337:Pfdn6
uniprot id: A0A8C5K3T0
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

51337:Kctd13
gene id: 51337:Kctd13
uniprot id: A0A8C5JYQ9
names: Similarity
messages: Belongs to the BACURD family.

51337:Dars1
gene id: 51337:Dars1
uniprot id: A0A8C5K735
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

51337:Chst1
gene id: 51337:Chst1
uniprot id: A0A8C5K781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

51337:Ccdc85b
gene id: 51337:Ccdc85b
uniprot id: A0A8C5KCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

51337:Calb1
gene id: 51337:Calb1
uniprot id: A0A8C5K9Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
messages: Interacts with RANBP9.

51337:Mtmr6
gene id: 51337:Mtmr6
uniprot id: A0A8C5KC60
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

51337:Tacstd2
gene id: 51337:Tacstd2
uniprot id: A0A8C5KKH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Ndufa12
gene id: 51337:Ndufa12
uniprot id: A0A8C5NW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:LOC101601425
gene id: 51337:LOC101601425
uniprot id: A0A8C5JYF4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

51337:Snw1
gene id: 51337:Snw1
uniprot id: A0A8C5LE84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

51337:Cnot9
gene id: 51337:Cnot9
uniprot id: A0A8C5JX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

51337:Immt
gene id: 51337:Immt
uniprot id: A0A8C5KKK9
uniprot id: A0A8C5KQ16
uniprot id: A0A8C5P029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

51337:Pi4ka
gene id: 51337:Pi4ka
uniprot id: A0A8C5KDK5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

51337:Ddi2
gene id: 51337:Ddi2
uniprot id: A0A8C5K694
names: Similarity
messages: Belongs to the DDI1 family.

51337:Cdc42
gene id: 51337:Cdc42
uniprot id: A0A8C5K8Z1
uniprot id: A0A8C5KDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
messages: centrosome

51337:Rpl7l1
gene id: 51337:Rpl7l1
uniprot id: A0A8C5LJE2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

51337:Galnt1
gene id: 51337:Galnt1
uniprot id: A0A8C5KBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Mrpl37
gene id: 51337:Mrpl37
uniprot id: A0A8C5JYC8
names: Subcellular Location Annotation
messages: Mitochondrion

51337:KEG00 p04
gene id: 51337:KEG00_p04
uniprot id: Q710S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

51337:Pdgfrl
gene id: 51337:Pdgfrl
uniprot id: A0A8C5NW85
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Secreted

51337:Kcnab1
gene id: 51337:Kcnab1
uniprot id: A0A8C5L280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

51337:Ndufv2
gene id: 51337:Ndufv2
uniprot id: A0A8C5KSF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

51337:Galnt16
gene id: 51337:Galnt16
uniprot id: A0A8C5K9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Slc26a9
gene id: 51337:Slc26a9
uniprot id: A0A8C5L6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.
messages: Membrane

51337:Btf3
gene id: 51337:Btf3
uniprot id: A0A8C5LLC5
names: Similarity
messages: Belongs to the NAC-beta family.

51337:Pla2g2e
gene id: 51337:Pla2g2e
uniprot id: A0A8C5P2D8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

51337:Chst3
gene id: 51337:Chst3
uniprot id: A0A8C5K509
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

51337:Rnd3
gene id: 51337:Rnd3
uniprot id: A0A8C5KJW5
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

51337:Tpra1
gene id: 51337:Tpra1
uniprot id: A0A8C5L5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

51337:LOC101593604
gene id: 51337:LOC101593604
uniprot id: A0A8C5KPG0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

51337:Aqp1
gene id: 51337:Aqp1
uniprot id: A0A8C5KYN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
messages: Membrane

51337:Gabpa
gene id: 51337:Gabpa
uniprot id: A0A8C5L383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Mkrn2
gene id: 51337:Mkrn2
uniprot id: A0A8C5L5W4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Olfm1
gene id: 51337:Olfm1
uniprot id: A0A8C5LHC4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

51337:Pbrm1
gene id: 51337:Pbrm1
uniprot id: A0A8C5L405
names: Subcellular Location Annotation
messages: Nucleus

51337:Gpr173
gene id: 51337:Gpr173
uniprot id: A0A8C5K2X2
names: Subcellular Location Annotation
messages: Membrane

51337:Nr1h2
gene id: 51337:Nr1h2
uniprot id: A0A8C5P220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

51337:Prox2
gene id: 51337:Prox2
uniprot id: A0A8C5L085
names: Subcellular Location Annotation
messages: Nucleus

51337:Cryba4
gene id: 51337:Cryba4
uniprot id: A0A8C5KGE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

51337:Mef2c
gene id: 51337:Mef2c
uniprot id: A0A8C5NYC7
names: Subcellular Location Annotation
messages: Nucleus

51337:Kdm5c
gene id: 51337:Kdm5c
uniprot id: A0A8C5KFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JARID1 histone demethylase family.
messages: Nucleus

51337:St8sia2
gene id: 51337:St8sia2
uniprot id: A0A8C5KI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Ptprm
gene id: 51337:Ptprm
uniprot id: A0A8C5P4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

51337:Ccdc65
gene id: 51337:Ccdc65
uniprot id: A0A8C5L209
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: flagellum axoneme

51337:Cpb1
gene id: 51337:Cpb1
uniprot id: A0A8C5K8K4
names: Similarity
messages: Belongs to the peptidase M14 family.

51337:LOC101598969
gene id: 51337:LOC101598969
uniprot id: A0A8C5K452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Lynx1
gene id: 51337:Lynx1
uniprot id: A0A8C5KCA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Fermt2
gene id: 51337:Fermt2
uniprot id: A0A8C5L4V5
names: Similarity
messages: Belongs to the kindlin family.

51337:Lnpk
gene id: 51337:Lnpk
uniprot id: A0A8C5KAR8
uniprot id: A0A8C5KFK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

51337:Npas1
gene id: 51337:Npas1
uniprot id: A0A8C5KVM4
names: Subcellular Location Annotation
messages: Nucleus

51337:Tmem41a
gene id: 51337:Tmem41a
uniprot id: A0A8C5KR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

51337:LOC101598985
gene id: 51337:LOC101598985
uniprot id: A0A8C5L8X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

51337:Gabra3
gene id: 51337:Gabra3
uniprot id: A0A8C5NUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Senp3
gene id: 51337:Senp3
uniprot id: A0A8C5JTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

51337:Ptgr1
gene id: 51337:Ptgr1
uniprot id: A0A8C5KEN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

51337:Slc5a8
gene id: 51337:Slc5a8
uniprot id: A0A8C5KYF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:Edc4
gene id: 51337:Edc4
uniprot id: A0A8C5NW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

51337:Lars1
gene id: 51337:Lars1
uniprot id: A0A8C5KP99
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:LOC101597871
gene id: 51337:LOC101597871
uniprot id: A0A8C5K910
names: Similarity
messages: Belongs to the FAM136 family.

51337:Slc26a3
gene id: 51337:Slc26a3
uniprot id: A0A8C5P556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Chloride/bicarbonate exchanger.
messages: Membrane

51337:Qpctl
gene id: 51337:Qpctl
uniprot id: A0A8C5K384
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

51337:Myh7b
gene id: 51337:Myh7b
uniprot id: A0A8C5KC69
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Cdk3
gene id: 51337:Cdk3
uniprot id: A0A8C5K0S2
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:LOC101593778
gene id: 51337:LOC101593778
uniprot id: A0A8C5KB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Aacs
gene id: 51337:Aacs
uniprot id: A0A8C5KNN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

51337:Slx9
gene id: 51337:Slx9
uniprot id: A0A8C5KSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

51337:Krt7
gene id: 51337:Krt7
uniprot id: A0A8C5L8A8
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Cwf19l1
gene id: 51337:Cwf19l1
uniprot id: A0A8C5KKN2
names: Similarity
messages: Belongs to the CWF19 family.

51337:Mcoln3
gene id: 51337:Mcoln3
uniprot id: A0A8C5LID6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

51337:Golga5
gene id: 51337:Golga5
uniprot id: A0A8C5LH06
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

51337:Spice1
gene id: 51337:Spice1
uniprot id: A0A8C5KIA7
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CEP120.
messages: centriole
messages: spindle

51337:Mc3r
gene id: 51337:Mc3r
uniprot id: A0A8C5NUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tk2
gene id: 51337:Tk2
uniprot id: A0A8C5K7Z3
names: Similarity
messages: Belongs to the DCK/DGK family.

51337:Hal
gene id: 51337:Hal
uniprot id: A0A8C5K673
names: Similarity
messages: Belongs to the PAL/histidase family.

51337:Pax4
gene id: 51337:Pax4
uniprot id: A0A8C5NWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

51337:Ndrg2
gene id: 51337:Ndrg2
uniprot id: A0A8C5KU49
uniprot id: A0A8C5KZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm
messages: growth cone

51337:Tspan33
gene id: 51337:Tspan33
uniprot id: A0A8C5JX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Hsd17b10
gene id: 51337:Hsd17b10
uniprot id: A0A8C5NZ83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Chst13
gene id: 51337:Chst13
uniprot id: A0A8C5K6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Vat1
gene id: 51337:Vat1
uniprot id: A0A8C5KX00
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

51337:Ckap2l
gene id: 51337:Ckap2l
uniprot id: A0A8C5KCY5
names: Similarity
messages: Belongs to the CKAP2 family.

51337:Cd3g
gene id: 51337:Cd3g
uniprot id: A0A8C5L696
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

51337:Slc39a12
gene id: 51337:Slc39a12
uniprot id: A0A8C5L321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

51337:Slc6a19
gene id: 51337:Slc6a19
uniprot id: A0A8C5KEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:Dhrs9
gene id: 51337:Dhrs9
uniprot id: A0A8C5K1W2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Rps8
gene id: 51337:Rps8
uniprot id: A0A8C5KZ88
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

51337:Ucn
gene id: 51337:Ucn
uniprot id: A0A8C5KKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

51337:Gpr158
gene id: 51337:Gpr158
uniprot id: A0A8C5JWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

51337:Foxk2
gene id: 51337:Foxk2
uniprot id: A0A8C5JYB8
names: Subcellular Location Annotation
messages: Nucleus

51337:Tom1l2
gene id: 51337:Tom1l2
uniprot id: A0A8C5KTM1
uniprot id: A0A8C5P021
names: Similarity
messages: Belongs to the TOM1 family.

51337:Abcd1
gene id: 51337:Abcd1
uniprot id: A0A8C5KF91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

51337:Olfml3
gene id: 51337:Olfml3
uniprot id: A0A8C5LDV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Wnt7a
gene id: 51337:Wnt7a
uniprot id: A0A8C5P043
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Rpl15
gene id: 51337:Rpl15
uniprot id: A0A8C5NZG7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

51337:Nipsnap1
gene id: 51337:Nipsnap1
uniprot id: A0A8C5KVP3
names: Similarity
messages: Belongs to the NipSnap family.

51337:Acsf3
gene id: 51337:Acsf3
uniprot id: A0A8C5KVG0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:LOC101601394
gene id: 51337:LOC101601394
uniprot id: A0A8C5KGL3
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

51337:Lama1
gene id: 51337:Lama1
uniprot id: A0A8C5LLU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

51337:LOC101612830
gene id: 51337:LOC101612830
uniprot id: A0A8C5LHE9
names: Subcellular Location Annotation
messages: Membrane

51337:Ypel4
gene id: 51337:Ypel4
uniprot id: A0A8C5KEV8
names: Similarity
messages: Belongs to the yippee family.

51337:LOC101608450
gene id: 51337:LOC101608450
uniprot id: A0A8C5KLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101610090
gene id: 51337:LOC101610090
uniprot id: A0A8C5KAM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Pgr
gene id: 51337:Pgr
uniprot id: A0A8C5P0C7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

51337:Panx3
gene id: 51337:Panx3
uniprot id: A0A8C5L2K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

51337:Nxph3
gene id: 51337:Nxph3
uniprot id: A0A8C5NV34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

51337:C8b
gene id: 51337:C8b
uniprot id: A0A8C5NWU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Elk3
gene id: 51337:Elk3
uniprot id: A0A8C5K7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Lrrc51
gene id: 51337:Lrrc51
uniprot id: A0A8C5NXA7
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Srp19
gene id: 51337:Srp19
uniprot id: A0A8C5KX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

51337:Sdc2
gene id: 51337:Sdc2
uniprot id: A0A8C5L1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

51337:Ppm1a
gene id: 51337:Ppm1a
uniprot id: A0A8C5L992
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

51337:Soga3
gene id: 51337:Soga3
uniprot id: A0A8C5L770
names: Similarity
messages: Belongs to the SOGA family.

51337:Atg16l1
gene id: 51337:Atg16l1
uniprot id: A0A8C5KMF2
uniprot id: A0A8C5NZT5
uniprot id: A0A8C5P063
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

51337:Oprm1
gene id: 51337:Oprm1
uniprot id: A0A8C5LNA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

51337:Hopx
gene id: 51337:Hopx
uniprot id: A0A8C5P1V6
names: Subcellular Location Annotation
messages: Nucleus

51337:Chrnb1
gene id: 51337:Chrnb1
uniprot id: A0A8C5KNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Polr1c
gene id: 51337:Polr1c
uniprot id: A0A8C5LBV7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

51337:Sptssa
gene id: 51337:Sptssa
uniprot id: A0A8C5KMF1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Spaca5
gene id: 51337:Spaca5
uniprot id: A0A8C5KA92
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

51337:Capn12
gene id: 51337:Capn12
uniprot id: A0A8C5KJ53
names: Similarity
messages: Belongs to the peptidase C2 family.

51337:Artn
gene id: 51337:Artn
uniprot id: A0A8C5KVQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

51337:Aspdh
gene id: 51337:Aspdh
uniprot id: A0A8C5KEK7
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

51337:Gria2
gene id: 51337:Gria2
uniprot id: A0A8C5KQ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Ctnnd1
gene id: 51337:Ctnnd1
uniprot id: A0A8C5K7E5
uniprot id: A0A8C5NX00
names: Similarity
messages: Belongs to the beta-catenin family.

51337:Tbr1
gene id: 51337:Tbr1
uniprot id: A0A8C5NVP4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Polr2g
gene id: 51337:Polr2g
uniprot id: A0A8C5NVJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

51337:Slc25a30
gene id: 51337:Slc25a30
uniprot id: A0A8C5KX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Olfml1
gene id: 51337:Olfml1
uniprot id: A0A8C5K890
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Bmp10
gene id: 51337:Bmp10
uniprot id: A0A8C5KQM0
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Ftl
gene id: 51337:Ftl
uniprot id: A0A8C5NUK3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

51337:Upf1
gene id: 51337:Upf1
uniprot id: A0A8C5LC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

51337:Slc9a8
gene id: 51337:Slc9a8
uniprot id: A0A8C5LG52
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

51337:Paip2
gene id: 51337:Paip2
uniprot id: A0A8C5KUS5
names: Similarity
messages: Belongs to the PAIP2 family.

51337:Ring1
gene id: 51337:Ring1
uniprot id: A0A8C5L8U9
names: Function
names: Subcellular Location Annotation
messages: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
messages: Nucleus speckle

51337:Ppox
gene id: 51337:Ppox
uniprot id: A0A8C5L2U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

51337:Pold2
gene id: 51337:Pold2
uniprot id: A0A8C5KHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

51337:Kdelr2
gene id: 51337:Kdelr2
uniprot id: A0A8C5K2Q6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Maml1
gene id: 51337:Maml1
uniprot id: A0A8C5P5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

51337:Adamts10
gene id: 51337:Adamts10
uniprot id: A0A8C5K945
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

51337:Sprtn
gene id: 51337:Sprtn
uniprot id: A0A8C5LC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

51337:Ca1
gene id: 51337:Ca1
uniprot id: A0A8C5P2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

51337:Srsf5
gene id: 51337:Srsf5
uniprot id: A0A8C5JW19
names: Similarity
messages: Belongs to the splicing factor SR family.

51337:Gsto1
gene id: 51337:Gsto1
uniprot id: A0A8C5KZF1
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

51337:Pih1d2
gene id: 51337:Pih1d2
uniprot id: A0A8C5L0V1
names: Similarity
messages: Belongs to the PIH1 family.

51337:Amd1
gene id: 51337:Amd1
uniprot id: A0A8C5K167
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

51337:Rpl35a
gene id: 51337:Rpl35a
uniprot id: A0A8C5P1M1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

51337:Golt1a
gene id: 51337:Golt1a
uniprot id: A0A8C5KU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

51337:Grm8
gene id: 51337:Grm8
uniprot id: A0A8C5KUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

51337:S100a5
gene id: 51337:S100a5
uniprot id: A0A8C5KZZ1
names: Similarity
messages: Belongs to the S-100 family.

51337:Mtnr1a
gene id: 51337:Mtnr1a
uniprot id: A0A8C5KEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
messages: Membrane

51337:Phf5a
gene id: 51337:Phf5a
uniprot id: A0A8C5NXE9
names: Similarity
messages: Belongs to the PHF5 family.

51337:Cacna2d1
gene id: 51337:Cacna2d1
uniprot id: A0A8C5P448
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

51337:Zfpm2
gene id: 51337:Zfpm2
uniprot id: A0A8C5NUB9
names: Subcellular Location Annotation
messages: Nucleus

51337:Rpl23a
gene id: 51337:Rpl23a
uniprot id: A0A8C5LLN2
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

51337:Ppp1ca
gene id: 51337:Ppp1ca
uniprot id: A0A8C5K8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

51337:Cpeb4
gene id: 51337:Cpeb4
uniprot id: A0A8C5L9Y9
uniprot id: A0A8C5LCU2
names: Similarity
messages: Belongs to the RRM CPEB family.

51337:Sftpc
gene id: 51337:Sftpc
uniprot id: A0A8C5NWU2
names: Function
names: Subcellular Location Annotation
messages: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
messages: surface film

51337:Cldn14
gene id: 51337:Cldn14
uniprot id: A0A8C5KI29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Dcps
gene id: 51337:Dcps
uniprot id: A0A8C5L9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

51337:Ntmt2
gene id: 51337:Ntmt2
uniprot id: A0A8C5LH38
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

51337:Dusp9
gene id: 51337:Dusp9
uniprot id: A0A8C5L0E1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

51337:Ca10
gene id: 51337:Ca10
uniprot id: A0A8C5KB57
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

51337:Ins
gene id: 51337:Ins
uniprot id: A0A8C5KCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

51337:Iars1
gene id: 51337:Iars1
uniprot id: A0A8C5NXW0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Ipo11
gene id: 51337:Ipo11
uniprot id: A0A8C5NVZ1
names: Subcellular Location Annotation
messages: Cytoplasm

51337:LOC101616871
gene id: 51337:LOC101616871
uniprot id: A0A8C5JWL1
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Ccdc126
gene id: 51337:Ccdc126
uniprot id: A0A8C5KCJ0
names: Subcellular Location Annotation
messages: Secreted

51337:Trim72
gene id: 51337:Trim72
uniprot id: A0A8C5K3D8
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle membrane
messages: sarcolemma

51337:Letmd1
gene id: 51337:Letmd1
uniprot id: A0A8C5LGQ8
names: Subcellular Location Annotation
messages: Membrane

51337:Shank1
gene id: 51337:Shank1
uniprot id: A0A8C5KIB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHANK family.
messages: Cytoplasm
messages: Postsynaptic density

51337:Tmem205
gene id: 51337:Tmem205
uniprot id: A0A8C5JVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

51337:Ifitm5
gene id: 51337:Ifitm5
uniprot id: A0A8C5K9N1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

51337:Fgf20
gene id: 51337:Fgf20
uniprot id: A0A8C5KTE1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Ppp4r3b
gene id: 51337:Ppp4r3b
uniprot id: A0A8C5KUR1
names: Similarity
messages: Belongs to the SMEK family.

51337:Hars2
gene id: 51337:Hars2
uniprot id: A0A8C5KLZ6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

51337:Rbp2
gene id: 51337:Rbp2
uniprot id: A0A8C5LB52
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:CUNH6orf58
gene id: 51337:CUNH6orf58
uniprot id: A0A8C5K623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

51337:Hsd17b7
gene id: 51337:Hsd17b7
uniprot id: A0A8C5KF67
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

51337:Pla2g12a
gene id: 51337:Pla2g12a
uniprot id: A0A8C5JX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

51337:Entpd2
gene id: 51337:Entpd2
uniprot id: A0A8C5L3G5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

51337:Pard6a
gene id: 51337:Pard6a
uniprot id: A0A8C5L570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cell membrane
messages: Cytoplasm
messages: tight junction

51337:Il1rapl1
gene id: 51337:Il1rapl1
uniprot id: A0A8C5KVI0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

51337:Jakmip2
gene id: 51337:Jakmip2
uniprot id: A0A8C5JTR8
names: Similarity
messages: Belongs to the JAKMIP family.

51337:Med22
gene id: 51337:Med22
uniprot id: A0A8C5K3N6
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

51337:Prpf38a
gene id: 51337:Prpf38a
uniprot id: A0A8C5KVB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

51337:Rab4a
gene id: 51337:Rab4a
uniprot id: A0A8C5L1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

51337:Cd82
gene id: 51337:Cd82
uniprot id: A0A8C5KAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Siva1
gene id: 51337:Siva1
uniprot id: A0A8C5P3C2
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus
messages: Phosphorylated by ABL2/ARG in response to oxidative stress.

51337:Duoxa1
gene id: 51337:Duoxa1
uniprot id: A0A8C5KFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

51337:Aimp2
gene id: 51337:Aimp2
uniprot id: A0A8C5LI20
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

51337:LOC101596540
gene id: 51337:LOC101596540
uniprot id: A0A8C5KLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Clcf1
gene id: 51337:Clcf1
uniprot id: A0A8C5L2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

51337:Gsto2
gene id: 51337:Gsto2
uniprot id: A0A8C5KMZ2
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

51337:Agpat5
gene id: 51337:Agpat5
uniprot id: A0A8C5L227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

51337:Lipm
gene id: 51337:Lipm
uniprot id: A0A8C5P0H0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

51337:Kif26a
gene id: 51337:Kif26a
uniprot id: A0A8C5JWF1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Tenm1
gene id: 51337:Tenm1
uniprot id: A0A8C5KIP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Aldh16a1
gene id: 51337:Aldh16a1
uniprot id: A0A8C5KVW8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

51337:Cnga1
gene id: 51337:Cnga1
uniprot id: A0A8C5LEJ1
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
messages: Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.

51337:Ndufa3
gene id: 51337:Ndufa3
uniprot id: A0A8C5L1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Calr
gene id: 51337:Calr
uniprot id: A0A8C5NTW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: Monomer.

51337:Dact1
gene id: 51337:Dact1
uniprot id: A0A8C5LI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

51337:Acaa2
gene id: 51337:Acaa2
uniprot id: A0A8C5P5B6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

51337:Trpc6
gene id: 51337:Trpc6
uniprot id: A0A8C5LC04
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101603692
gene id: 51337:LOC101603692
uniprot id: A0A8C5L339
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

51337:Atp1b4
gene id: 51337:Atp1b4
uniprot id: A0A8C5NY03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

51337:Gata5
gene id: 51337:Gata5
uniprot id: A0A8C5KWV9
names: Subcellular Location Annotation
messages: Nucleus

51337:P2ry2
gene id: 51337:P2ry2
uniprot id: A0A8C5KG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101606685
gene id: 51337:LOC101606685
uniprot id: A0A8C5K0L0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Tsn
gene id: 51337:Tsn
uniprot id: A0A8C5K702
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

51337:LOC101599264
gene id: 51337:LOC101599264
uniprot id: A0A8C5KTQ0
names: Similarity
messages: Belongs to the TPD52 family.

51337:Rpe
gene id: 51337:Rpe
uniprot id: A0A8C5KG36
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

51337:Uroc1
gene id: 51337:Uroc1
uniprot id: A0A8C5K959
names: Similarity
messages: Belongs to the urocanase family.

51337:Dennd6b
gene id: 51337:Dennd6b
uniprot id: A0A8C5JZP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

51337:LOC101606975
gene id: 51337:LOC101606975
uniprot id: A0A8C5P0W3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Pnpo
gene id: 51337:Pnpo
uniprot id: A0A8C5LIK2
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

51337:Myh4
gene id: 51337:Myh4
uniprot id: A0A8C5KUG6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Wnt7b
gene id: 51337:Wnt7b
uniprot id: A0A8C5L0K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Rarg
gene id: 51337:Rarg
uniprot id: A0A8C5L4A6
uniprot id: A0A8C5L5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Ing5
gene id: 51337:Ing5
uniprot id: A0A8C5KVA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

51337:Prrx1
gene id: 51337:Prrx1
uniprot id: A0A8C5KM84
uniprot id: A0A8C5NZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

51337:Ntf3
gene id: 51337:Ntf3
uniprot id: A0A8C5K2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

51337:Tent5b
gene id: 51337:Tent5b
uniprot id: A0A8C5KYK7
names: Similarity
messages: Belongs to the TENT family.

51337:Tmem107
gene id: 51337:Tmem107
uniprot id: A0A8C5KMJ1
names: Subcellular Location Annotation
messages: Membrane

51337:Ufd1
gene id: 51337:Ufd1
uniprot id: A0A8C5KTE0
names: Similarity
messages: Belongs to the UFD1 family.

51337:Pgm1
gene id: 51337:Pgm1
uniprot id: A0A8C5KBM2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

51337:Srp14
gene id: 51337:Srp14
uniprot id: A0A8C5L305
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

51337:Mmp9
gene id: 51337:Mmp9
uniprot id: A0A8C5KD64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with LCN2. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.
messages: extracellular matrix

51337:LOC101593494
gene id: 51337:LOC101593494
uniprot id: A0A8C5L9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Cav3
gene id: 51337:Cav3
uniprot id: A0A8C5LIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

51337:Rdh12
gene id: 51337:Rdh12
uniprot id: A0A8C5K6S1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Kat5
gene id: 51337:Kat5
uniprot id: A0A8C5LKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

51337:Ptx3
gene id: 51337:Ptx3
uniprot id: A0A8C5LDC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Inhba
gene id: 51337:Inhba
uniprot id: A0A8C5K4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

51337:Ddx4
gene id: 51337:Ddx4
uniprot id: A0A8C5KVL1
uniprot id: A0A8C5P0F1
names: Similarity
messages: Belongs to the DEAD box helicase family.

51337:Tmem265
gene id: 51337:Tmem265
uniprot id: A0A8C5L2E6
names: Similarity
messages: Belongs to the CD225/Dispanin family.

51337:Avpr1b
gene id: 51337:Avpr1b
uniprot id: A0A8C5JVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

51337:Gng7
gene id: 51337:Gng7
uniprot id: A0A8C5LFD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:Il23a
gene id: 51337:Il23a
uniprot id: A0A8C5P229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

51337:Chdh
gene id: 51337:Chdh
uniprot id: A0A8C5KHV6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

51337:Rock1
gene id: 51337:Rock1
uniprot id: A0A8C5KI90
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

51337:Mrpl11
gene id: 51337:Mrpl11
uniprot id: A0A8C5P346
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

51337:Rpl27a
gene id: 51337:Rpl27a
uniprot id: A0A8C5KD04
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

51337:Scn2a
gene id: 51337:Scn2a
uniprot id: A0A8C5KIA2
uniprot id: A0A8C5KKT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

51337:Vegfb
gene id: 51337:Vegfb
uniprot id: A0A8C5K3F4
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

51337:Cavin2
gene id: 51337:Cavin2
uniprot id: A0A8C5P0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

51337:Lyplal1
gene id: 51337:Lyplal1
uniprot id: A0A8C5KS08
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

51337:Rps24
gene id: 51337:Rps24
uniprot id: A0A8C5K7Z1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

51337:Slc30a3
gene id: 51337:Slc30a3
uniprot id: A0A8C5JVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

51337:LOC101614713
gene id: 51337:LOC101614713
uniprot id: A0A8C5JZH4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Gbgt1
gene id: 51337:Gbgt1
uniprot id: A0A8C5LCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

51337:Ruvbl1
gene id: 51337:Ruvbl1
uniprot id: A0A8C5LHQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

51337:Utp3
gene id: 51337:Utp3
uniprot id: A0A8C5KNH4
names: Similarity
messages: Belongs to the SAS10 family.

51337:Cyria
gene id: 51337:Cyria
uniprot id: A0A8C5K6T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

51337:Pa2g4
gene id: 51337:Pa2g4
uniprot id: A0A8C5LKY4
names: Similarity
messages: Belongs to the peptidase M24 family.

51337:Acsf2
gene id: 51337:Acsf2
uniprot id: A0A8C5KBB1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Tph2
gene id: 51337:Tph2
uniprot id: A0A8C5LDG5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

51337:Washc3
gene id: 51337:Washc3
uniprot id: A0A8C5L773
names: Similarity
messages: Belongs to the CCDC53 family.

51337:Tes
gene id: 51337:Tes
uniprot id: A0A8C5P2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: Cytoplasm
messages: focal adhesion

51337:Med6
gene id: 51337:Med6
uniprot id: A0A8C5K200
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

51337:Pdxk
gene id: 51337:Pdxk
uniprot id: A0A8C5KRQ6
names: Similarity
messages: Belongs to the pyridoxine kinase family.

51337:Dpys
gene id: 51337:Dpys
uniprot id: A0A8C5K5E3
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

51337:Lgi4
gene id: 51337:Lgi4
uniprot id: A0A8C5KVL5
names: Subcellular Location Annotation
messages: Secreted

51337:Pih1d1
gene id: 51337:Pih1d1
uniprot id: A0A8C5LJZ6
names: Similarity
messages: Belongs to the PIH1 family.

51337:Lhx1
gene id: 51337:Lhx1
uniprot id: A0A8C5LLS6
names: Subcellular Location Annotation
messages: Nucleus

51337:Ndufb7
gene id: 51337:Ndufb7
uniprot id: A0A8C5NUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

51337:Eif6
gene id: 51337:Eif6
uniprot id: A0A8C5NVF3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

51337:Zmynd10
gene id: 51337:Zmynd10
uniprot id: A0A8C5KK16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

51337:Scarb2
gene id: 51337:Scarb2
uniprot id: A0A8C5JXH0
names: Similarity
messages: Belongs to the CD36 family.

51337:Lxn
gene id: 51337:Lxn
uniprot id: A0A8C5NYR6
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

51337:Dnaja2
gene id: 51337:Dnaja2
uniprot id: A0A8C5JVM8
names: Subcellular Location Annotation
messages: Membrane

51337:Psma5
gene id: 51337:Psma5
uniprot id: A0A8C5KFD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

51337:Col4a1
gene id: 51337:Col4a1
uniprot id: A0A8C5L911
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

51337:LOC101614362
gene id: 51337:LOC101614362
uniprot id: A0A8C5JZJ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

51337:Kars1
gene id: 51337:Kars1
uniprot id: A0A8C5L4A9
uniprot id: A0A8C5L6G3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

51337:Rasgrp4
gene id: 51337:Rasgrp4
uniprot id: A0A8C5KYM8
names: Similarity
messages: Belongs to the RASGRP family.

51337:Il10
gene id: 51337:Il10
uniprot id: A0A8C5KI75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

51337:Unc5c
gene id: 51337:Unc5c
uniprot id: A0A8C5L859
uniprot id: A0A8C5LEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

51337:Wars1
gene id: 51337:Wars1
uniprot id: A0A8C5P4K8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Gsc2
gene id: 51337:Gsc2
uniprot id: A0A8C5K350
names: Subcellular Location Annotation
messages: Nucleus

51337:Stx17
gene id: 51337:Stx17
uniprot id: A0A8C5KR61
names: Similarity
messages: Belongs to the syntaxin family.

51337:Eda
gene id: 51337:Eda
uniprot id: A0A8C5LCY4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

51337:Dctn1
gene id: 51337:Dctn1
uniprot id: A0A8C5JXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

51337:Tmem30a
gene id: 51337:Tmem30a
uniprot id: A0A8C5KS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

51337:Pold3
gene id: 51337:Pold3
uniprot id: A0A8C5KUV6
names: Subcellular Location Annotation
messages: Nucleus

51337:Mrfap1
gene id: 51337:Mrfap1
uniprot id: A0A8C5K208
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

51337:Cse1l
gene id: 51337:Cse1l
uniprot id: A0A8C5KU86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

51337:Dtymk
gene id: 51337:Dtymk
uniprot id: A0A8C5KXK1
names: Similarity
messages: Belongs to the thymidylate kinase family.

51337:Slc6a4
gene id: 51337:Slc6a4
uniprot id: A0A8C5K8S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
messages: Synapse
messages: focal adhesion

51337:Bcat2
gene id: 51337:Bcat2
uniprot id: A0A8C5P294
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

51337:U2af2
gene id: 51337:U2af2
uniprot id: A0A8C5L010
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

51337:LOC101610469
gene id: 51337:LOC101610469
uniprot id: A0A8C5K510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Ttr
gene id: 51337:Ttr
uniprot id: A0A8C5KJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

51337:Spta1
gene id: 51337:Spta1
uniprot id: A0A8C5K6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

51337:Tmem33
gene id: 51337:Tmem33
uniprot id: A0A8C5KPQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

51337:Eif3e
gene id: 51337:Eif3e
uniprot id: A0A8C5K2R4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

51337:Ak2
gene id: 51337:Ak2
uniprot id: A0A8C5P4B0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

51337:Prmt7
gene id: 51337:Prmt7
uniprot id: A0A8C5JZ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

51337:LOC101593599
gene id: 51337:LOC101593599
uniprot id: A0A8C5K030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

51337:Ubl4a
gene id: 51337:Ubl4a
uniprot id: A0A8C5P558
names: Subcellular Location Annotation
messages: cytosol

51337:Sfrp4
gene id: 51337:Sfrp4
uniprot id: A0A8C5LGE1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Crtc3
gene id: 51337:Crtc3
uniprot id: A0A8C5L5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

51337:Cpn1
gene id: 51337:Cpn1
uniprot id: A0A8C5KXC6
names: Similarity
messages: Belongs to the peptidase M14 family.

51337:Rbbp8
gene id: 51337:Rbbp8
uniprot id: A0A8C5LGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

51337:Lcat
gene id: 51337:Lcat
uniprot id: A0A8C5K2R6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

51337:LOC101604400
gene id: 51337:LOC101604400
uniprot id: A0A8C5P0M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

51337:Srsf1
gene id: 51337:Srsf1
uniprot id: A0A8C5NU99
names: Similarity
messages: Belongs to the splicing factor SR family.

51337:Uhrf2
gene id: 51337:Uhrf2
uniprot id: A0A8C5LFX2
names: Subcellular Location Annotation
messages: Nucleus

51337:Asb9
gene id: 51337:Asb9
uniprot id: A0A8C5L256
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

51337:Smoc2
gene id: 51337:Smoc2
uniprot id: A0A8C5K6J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Gem
gene id: 51337:Gem
uniprot id: A0A8C5LJJ5
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

51337:S1pr1
gene id: 51337:S1pr1
uniprot id: A0A8C5KCC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Gucy2c
gene id: 51337:Gucy2c
uniprot id: A0A8C5L596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

51337:LOC101594823
gene id: 51337:LOC101594823
uniprot id: A0A8C5KIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Lhfpl2
gene id: 51337:Lhfpl2
uniprot id: A0A8C5KXD7
names: Subcellular Location Annotation
messages: Membrane

51337:Sparc
gene id: 51337:Sparc
uniprot id: A0A8C5NVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

51337:Adrm1
gene id: 51337:Adrm1
uniprot id: A0A8C5KCP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

51337:Eva1a
gene id: 51337:Eva1a
uniprot id: A0A8C5JVQ3
names: Similarity
messages: Belongs to the EVA1 family.

51337:Dock5
gene id: 51337:Dock5
uniprot id: A0A8C5KG14
names: Similarity
messages: Belongs to the DOCK family.

51337:Il16
gene id: 51337:Il16
uniprot id: A0A8C5LGY8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

51337:Ggnbp2
gene id: 51337:Ggnbp2
uniprot id: A0A8C5L3M5
uniprot id: A0A8C5L7G7
names: Function
messages: May be involved in spermatogenesis.

51337:Bet1
gene id: 51337:Bet1
uniprot id: A0A8C5L7S1
names: Subcellular Location Annotation
messages: Membrane

51337:Gabra1
gene id: 51337:Gabra1
uniprot id: A0A8C5JVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Mrps14
gene id: 51337:Mrps14
uniprot id: A0A8C5JZW8
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

51337:Ggt7
gene id: 51337:Ggt7
uniprot id: A0A8C5KUR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

51337:Plcg2
gene id: 51337:Plcg2
uniprot id: A0A8C5LCE7
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

51337:Lap3
gene id: 51337:Lap3
uniprot id: A0A8C5KTS5
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

51337:LOC101593735
gene id: 51337:LOC101593735
uniprot id: A0A8C5NUG7
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Timm13
gene id: 51337:Timm13
uniprot id: A0A8C5L8M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

51337:Mapk1ip1l
gene id: 51337:Mapk1ip1l
uniprot id: A0A8C5KXI8
names: Similarity
messages: Belongs to the MISS family.

51337:Mtr
gene id: 51337:Mtr
uniprot id: A0A8C5L142
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

51337:Pnn
gene id: 51337:Pnn
uniprot id: A0A8C5KR79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

51337:S1pr5
gene id: 51337:S1pr5
uniprot id: A0A8C5KJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Mb
gene id: 51337:Mb
uniprot id: A0A8C5P0K4
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

51337:LOC101595707
gene id: 51337:LOC101595707
uniprot id: A0A8C5KGR8
names: Similarity
messages: Belongs to the NDK family.

51337:Mrpl4
gene id: 51337:Mrpl4
uniprot id: A0A8C5K9S5
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

51337:Gabrg2
gene id: 51337:Gabrg2
uniprot id: A0A8C5LEY3
uniprot id: A0A8C5P5U0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Tmem258
gene id: 51337:Tmem258
uniprot id: A0A8C5LE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

51337:Eno2
gene id: 51337:Eno2
uniprot id: A0A8C5P442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

51337:Adcy3
gene id: 51337:Adcy3
uniprot id: A0A8C5KZZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

51337:Pelp1
gene id: 51337:Pelp1
uniprot id: A0A8C5KEL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

51337:Ndufa2
gene id: 51337:Ndufa2
uniprot id: A0A8C5LFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Ap1g2
gene id: 51337:Ap1g2
uniprot id: A0A8C5LG19
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

51337:Tmem254
gene id: 51337:Tmem254
uniprot id: A0A8C5P5Q3
names: Subcellular Location Annotation
messages: Membrane

51337:Aqp2
gene id: 51337:Aqp2
uniprot id: A0A8C5LF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

51337:Fitm1
gene id: 51337:Fitm1
uniprot id: A0A8C5P2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol.

51337:LOC101608198
gene id: 51337:LOC101608198
uniprot id: A0A8C5KE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

51337:Npy1r
gene id: 51337:Npy1r
uniprot id: A0A8C5KC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tom1
gene id: 51337:Tom1
uniprot id: A0A8C5P5A1
names: Similarity
messages: Belongs to the TOM1 family.

51337:Tceal1
gene id: 51337:Tceal1
uniprot id: A0A8C5KBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family. TFA subfamily.
messages: Nucleus

51337:Tmed9
gene id: 51337:Tmed9
uniprot id: A0A8C5KNF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Puf60
gene id: 51337:Puf60
uniprot id: A0A8C5JZ84
uniprot id: A0A8C5K1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

51337:Ntsr2
gene id: 51337:Ntsr2
uniprot id: A0A8C5KD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Slc16a3
gene id: 51337:Slc16a3
uniprot id: A0A8C5LHS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

51337:Serpina12
gene id: 51337:Serpina12
uniprot id: A0A8C5K6C9
names: Similarity
messages: Belongs to the serpin family.

51337:Ajap1
gene id: 51337:Ajap1
uniprot id: A0A8C5KWH5
names: Subcellular Location Annotation
messages: Membrane

51337:Tnp1
gene id: 51337:Tnp1
uniprot id: A0A8C5KS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 1 family.
messages: Nucleus

51337:Nmnat2
gene id: 51337:Nmnat2
uniprot id: A0A8C5L891
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

51337:Tm9sf4
gene id: 51337:Tm9sf4
uniprot id: A0A8C5P132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

51337:Exoc4
gene id: 51337:Exoc4
uniprot id: A0A8C5NYC6
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

51337:Tigd2
gene id: 51337:Tigd2
uniprot id: A0A8C5NUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

51337:Eef1b2
gene id: 51337:Eef1b2
uniprot id: A0A8C5K295
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

51337:Ccn5
gene id: 51337:Ccn5
uniprot id: A0A8C5KBN8
names: Similarity
messages: Belongs to the CCN family.

51337:Bak1
gene id: 51337:Bak1
uniprot id: A0A8C5K2V5
names: Similarity
messages: Belongs to the Bcl-2 family.

51337:Slc7a8
gene id: 51337:Slc7a8
uniprot id: A0A8C5LGC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

51337:Krt222
gene id: 51337:Krt222
uniprot id: A0A8C5LDQ3
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Zscan2
gene id: 51337:Zscan2
uniprot id: A0A8C5LGN5
names: Subcellular Location Annotation
messages: Nucleus

51337:Yif1a
gene id: 51337:Yif1a
uniprot id: A0A8C5L6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

51337:Erlin2
gene id: 51337:Erlin2
uniprot id: A0A8C5KPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

51337:Dpm3
gene id: 51337:Dpm3
uniprot id: A0A8C5KB54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

51337:Zdhhc8
gene id: 51337:Zdhhc8
uniprot id: A0A8C5KBC9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Pfkm
gene id: 51337:Pfkm
uniprot id: A0A8C5L8C9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Rcan2
gene id: 51337:Rcan2
uniprot id: A0A8C5KX27
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

51337:Serpinb7
gene id: 51337:Serpinb7
uniprot id: A0A8C5L0Z5
names: Similarity
messages: Belongs to the serpin family.

51337:Enkd1
gene id: 51337:Enkd1
uniprot id: A0A8C5P2W9
names: Subcellular Location Annotation
messages: cilium axoneme

51337:Anxa1
gene id: 51337:Anxa1
uniprot id: A0A8C5KNR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors. Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration. Promotes resolution of inflammation and wound healing. Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2.
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium
messages: extracellular exosome
messages: extracellular space
messages: phagocytic cup
messages: secretory vesicle lumen

51337:LOC101608793
gene id: 51337:LOC101608793
uniprot id: A0A8C5L864
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

51337:Cacnb4
gene id: 51337:Cacnb4
uniprot id: A0A8C5KVM3
uniprot id: A0A8C5P142
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

51337:Kcnk16
gene id: 51337:Kcnk16
uniprot id: A0A8C5K0W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

51337:Fam83a
gene id: 51337:Fam83a
uniprot id: A0A8C5P2C6
names: Similarity
messages: Belongs to the FAM83 family.

51337:Spam1
gene id: 51337:Spam1
uniprot id: A0A8C5P4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

51337:Fmnl3
gene id: 51337:Fmnl3
uniprot id: A0A8C5NZT3
names: Similarity
messages: Belongs to the formin homology family.

51337:Znf503
gene id: 51337:Znf503
uniprot id: A0A8C5KFD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

51337:Gga1
gene id: 51337:Gga1
uniprot id: A0A8C5KJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

51337:Csrnp3
gene id: 51337:Csrnp3
uniprot id: A0A8C5L4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

51337:Il17rb
gene id: 51337:Il17rb
uniprot id: A0A8C5L3X3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Ndel1
gene id: 51337:Ndel1
uniprot id: A0A8C5KAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

51337:Cdx1
gene id: 51337:Cdx1
uniprot id: A0A8C5P2L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

51337:Ppp4r3a
gene id: 51337:Ppp4r3a
uniprot id: A0A8C5LMS6
names: Similarity
messages: Belongs to the SMEK family.

51337:Sh3bgrl3
gene id: 51337:Sh3bgrl3
uniprot id: A0A8C5LJ57
names: Similarity
messages: Belongs to the SH3BGR family.

51337:Rab39a
gene id: 51337:Rab39a
uniprot id: A0A8C5LBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

51337:Vim
gene id: 51337:Vim
uniprot id: A0A8C5K4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
messages: Membrane
messages: Nucleus matrix
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

51337:Brk1
gene id: 51337:Brk1
uniprot id: A0A8C5LAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

51337:Rita1
gene id: 51337:Rita1
uniprot id: A0A8C5KK19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

51337:Klhl15
gene id: 51337:Klhl15
uniprot id: A0A8C5KGS8
names: Subcellular Location Annotation
messages: Nucleus

51337:Psmb3
gene id: 51337:Psmb3
uniprot id: A0A8C5LIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

51337:Pde10a
gene id: 51337:Pde10a
uniprot id: A0A8C5NWW5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Aar2
gene id: 51337:Aar2
uniprot id: A0A8C5KAJ1
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

51337:P2rx7
gene id: 51337:P2rx7
uniprot id: A0A8C5LD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

51337:Vwc2l
gene id: 51337:Vwc2l
uniprot id: A0A8C5L6Z8
names: Subcellular Location Annotation
messages: Synapse

51337:Mid1
gene id: 51337:Mid1
uniprot id: A0A8C5K642
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

51337:Nkx3-2
gene id: 51337:Nkx3-2
uniprot id: A0A8C5K886
names: Subcellular Location Annotation
messages: Nucleus

51337:Slc7a3
gene id: 51337:Slc7a3
uniprot id: A0A8C5L2Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

51337:LOC101608473
gene id: 51337:LOC101608473
uniprot id: A0A8C5NY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Dand5
gene id: 51337:Dand5
uniprot id: A0A8C5KC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

51337:Phlda3
gene id: 51337:Phlda3
uniprot id: A0A8C5KCW3
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Rps23
gene id: 51337:Rps23
uniprot id: A0A8C5KIJ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

51337:Cysltr2
gene id: 51337:Cysltr2
uniprot id: A0A8C5KEC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Galm
gene id: 51337:Galm
uniprot id: A0A8C5LK88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

51337:Ppfia3
gene id: 51337:Ppfia3
uniprot id: A0A8C5LGA4
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

51337:LOC101595971
gene id: 51337:LOC101595971
uniprot id: A0A8C5P3D0
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Hoxb1
gene id: 51337:Hoxb1
uniprot id: A0A8C5K0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

51337:Rad9a
gene id: 51337:Rad9a
uniprot id: A0A8C5NYQ3
names: Similarity
messages: Belongs to the rad9 family.

51337:Krtcap2
gene id: 51337:Krtcap2
uniprot id: A0A8C5LFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

51337:Ebna1bp2
gene id: 51337:Ebna1bp2
uniprot id: A0A8C5NXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

51337:Ppia
gene id: 51337:Ppia
uniprot id: A0A8C5KSS2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

51337:C5
gene id: 51337:C5
uniprot id: A0A8C5P629
names: Subcellular Location Annotation
messages: Secreted

51337:Scn1b
gene id: 51337:Scn1b
uniprot id: A0A8C5KKD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN1B (TC 8.A.17) family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon

51337:Pik3r2
gene id: 51337:Pik3r2
uniprot id: A0A8C5K367
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

51337:Mtg2
gene id: 51337:Mtg2
uniprot id: A0A8C5NWG9
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

51337:Gfra2
gene id: 51337:Gfra2
uniprot id: A0A8C5P377
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

51337:Dohh
gene id: 51337:Dohh
uniprot id: A0A8C5LJK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

51337:Myo1a
gene id: 51337:Myo1a
uniprot id: A0A8C5KJ62
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Hnrnpa1
gene id: 51337:Hnrnpa1
uniprot id: A0A8C5LI53
uniprot id: A0A8C5LK34
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Atg9a
gene id: 51337:Atg9a
uniprot id: A0A8C5NWP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

51337:Eva1b
gene id: 51337:Eva1b
uniprot id: A0A8C5NUC1
names: Similarity
messages: Belongs to the EVA1 family.

51337:Awat1
gene id: 51337:Awat1
uniprot id: A0A8C5LG48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Cblif
gene id: 51337:Cblif
uniprot id: A0A8C5KYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

51337:Vps13b
gene id: 51337:Vps13b
uniprot id: A0A8C5KXQ4
uniprot id: A0A8C5KYL6
names: Similarity
messages: Belongs to the VPS13 family.

51337:Dhx58
gene id: 51337:Dhx58
uniprot id: A0A8C5JYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

51337:LOC101595823
gene id: 51337:LOC101595823
uniprot id: A0A8C5P491
names: Similarity
messages: Belongs to the intermediate filament family.

51337:LOC101606354
gene id: 51337:LOC101606354
uniprot id: A0A8C5KA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

51337:Sv2b
gene id: 51337:Sv2b
uniprot id: A0A8C5LIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

51337:Ube4b
gene id: 51337:Ube4b
uniprot id: A0A8C5K5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

51337:Ntng2
gene id: 51337:Ntng2
uniprot id: A0A8C5L2Q4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Alx4
gene id: 51337:Alx4
uniprot id: A0A8C5KJ70
names: Subcellular Location Annotation
messages: Nucleus

51337:Actr6
gene id: 51337:Actr6
uniprot id: A0A8C5NY49
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

51337:Septin9
gene id: 51337:Septin9
uniprot id: A0A8C5KVQ1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

51337:Ca11
gene id: 51337:Ca11
uniprot id: A0A8C5LC22
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

51337:Slc27a5
gene id: 51337:Slc27a5
uniprot id: A0A8C5K4I2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Limk2
gene id: 51337:Limk2
uniprot id: A0A8C5KIB4
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

51337:Cadm2
gene id: 51337:Cadm2
uniprot id: A0A8C5NUJ5
names: Similarity
messages: Belongs to the nectin family.

51337:Cdc34
gene id: 51337:Cdc34
uniprot id: A0A8C5L1E1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Slc16a14
gene id: 51337:Slc16a14
uniprot id: A0A8C5KCJ6
names: Subcellular Location Annotation
messages: Membrane

51337:Gja1
gene id: 51337:Gja1
uniprot id: A0A8C5K294
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Endoplasmic reticulum
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Jakmip3
gene id: 51337:Jakmip3
uniprot id: A0A8C5KE97
names: Similarity
messages: Belongs to the JAKMIP family.

51337:Canx
gene id: 51337:Canx
uniprot id: A0A8C5LAQ0
names: Similarity
messages: Belongs to the calreticulin family.

51337:Gpr85
gene id: 51337:Gpr85
uniprot id: A0A8C5KXX7
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101594363
gene id: 51337:LOC101594363
uniprot id: A0A8C5NXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

51337:Sec22c
gene id: 51337:Sec22c
uniprot id: A0A8C5NVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

51337:Dph2
gene id: 51337:Dph2
uniprot id: A0A8C5KYG1
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

51337:Dlx3
gene id: 51337:Dlx3
uniprot id: A0A8C5K376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

51337:LOC105944937
gene id: 51337:LOC105944937
uniprot id: A0A8C5KLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101613224
gene id: 51337:LOC101613224
uniprot id: A0A8C5LG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Monomer. Homodimer. Homotetramer.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. May increase spectral sensitivity in dim light.

51337:Plscr5
gene id: 51337:Plscr5
uniprot id: A0A8C5NTZ5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

51337:Mov10
gene id: 51337:Mov10
uniprot id: A0A8C5KV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

51337:Tgfbr2
gene id: 51337:Tgfbr2
uniprot id: A0A8C5K707
uniprot id: A0A8C5K9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

51337:Ddah2
gene id: 51337:Ddah2
uniprot id: A0A8C5KEN6
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

51337:Rptor
gene id: 51337:Rptor
uniprot id: A0A8C5KWA0
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

51337:Mall
gene id: 51337:Mall
uniprot id: A0A8C5KZE3
names: Subcellular Location Annotation
messages: Membrane

51337:Cdk19
gene id: 51337:Cdk19
uniprot id: A0A8C5P4W3
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Grem1
gene id: 51337:Grem1
uniprot id: A0A8C5KH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

51337:Rdh8
gene id: 51337:Rdh8
uniprot id: A0A8C5KW34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

51337:Ywhaz
gene id: 51337:Ywhaz
uniprot id: A0A8C5JYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

51337:Cpsf4
gene id: 51337:Cpsf4
uniprot id: A0A8C5L0U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

51337:Gpm6a
gene id: 51337:Gpm6a
uniprot id: A0A8C5P391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

51337:Slc19a1
gene id: 51337:Slc19a1
uniprot id: A0A8C5P3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

51337:Srp72
gene id: 51337:Srp72
uniprot id: A0A8C5KXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

51337:Nae1
gene id: 51337:Nae1
uniprot id: A0A8C5P387
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

51337:Meox1
gene id: 51337:Meox1
uniprot id: A0A8C5KTA2
names: Subcellular Location Annotation
messages: Nucleus

51337:Mboat1
gene id: 51337:Mboat1
uniprot id: A0A8C5LF39
names: Subcellular Location Annotation
messages: Membrane

51337:Cpne5
gene id: 51337:Cpne5
uniprot id: A0A8C5KDX0
names: Similarity
messages: Belongs to the copine family.

51337:Ttyh3
gene id: 51337:Ttyh3
uniprot id: A0A8C5K1N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable chloride channel.

51337:Calcb
gene id: 51337:Calcb
uniprot id: A0A8C5NW56
names: Similarity
messages: Belongs to the calcitonin family.

51337:Babam2
gene id: 51337:Babam2
uniprot id: A0A8C5LES6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

51337:Cnep1r1
gene id: 51337:Cnep1r1
uniprot id: A0A8C5P128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

51337:Uts2b
gene id: 51337:Uts2b
uniprot id: A0A8C5K832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

51337:Ung
gene id: 51337:Ung
uniprot id: A0A8C5KRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Monomer. Interacts with FAM72A.
messages: Nucleus

51337:Gpr39
gene id: 51337:Gpr39
uniprot id: A0A8C5K1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Qsox2
gene id: 51337:Qsox2
uniprot id: A0A8C5P0J0
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

51337:Gal
gene id: 51337:Gal
uniprot id: A0A8C5KQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

51337:Kcnab2
gene id: 51337:Kcnab2
uniprot id: A0A8C5L0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

51337:LOC101602983
gene id: 51337:LOC101602983
uniprot id: A0A8C5K6M7
names: Subunit
messages: Interacts with hair keratins.

51337:Hoxc6
gene id: 51337:Hoxc6
uniprot id: A0A8C5P3X1
names: Subcellular Location Annotation
messages: Nucleus

51337:Pla2g2d
gene id: 51337:Pla2g2d
uniprot id: A0A8C5KNX5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

51337:Dars2
gene id: 51337:Dars2
uniprot id: A0A8C5LIG1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

51337:Lpar2
gene id: 51337:Lpar2
uniprot id: A0A8C5LCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Ldb1
gene id: 51337:Ldb1
uniprot id: A0A8C5KB51
uniprot id: A0A8C5KC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus

51337:Icam5
gene id: 51337:Icam5
uniprot id: A0A8C5KTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

51337:Apoa4
gene id: 51337:Apoa4
uniprot id: A0A8C5KUE0
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

51337:Pah
gene id: 51337:Pah
uniprot id: A0A8C5L0K9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

51337:KEG00 p05
gene id: 51337:KEG00_p05
uniprot id: Q710S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Fbxo31
gene id: 51337:Fbxo31
uniprot id: A0A8C5LH98
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

51337:Nt5e
gene id: 51337:Nt5e
uniprot id: A0A8C5LC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

51337:Tspan6
gene id: 51337:Tspan6
uniprot id: A0A8C5NZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Fgf11
gene id: 51337:Fgf11
uniprot id: A0A8C5P0G5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Nrp1
gene id: 51337:Nrp1
uniprot id: A0A8C5LDS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Laptm4a
gene id: 51337:Laptm4a
uniprot id: A0A8C5JXW8
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

51337:Ntsr1
gene id: 51337:Ntsr1
uniprot id: A0A8C5P2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Cpne7
gene id: 51337:Cpne7
uniprot id: A0A8C5JX87
names: Similarity
messages: Belongs to the copine family.

51337:Aldh1a3
gene id: 51337:Aldh1a3
uniprot id: A0A8C5K196
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

51337:Rtraf
gene id: 51337:Rtraf
uniprot id: A0A8C5P4P9
names: Similarity
messages: Belongs to the RTRAF family.

51337:LOC101605273
gene id: 51337:LOC101605273
uniprot id: A0A8C5KIR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

51337:LOC101601497
gene id: 51337:LOC101601497
uniprot id: A0A8C5K3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

51337:Pdhb
gene id: 51337:Pdhb
uniprot id: A0A8C5KSZ0
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

51337:Gspt1
gene id: 51337:Gspt1
uniprot id: A0A8C5KQK8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

51337:Cenpl
gene id: 51337:Cenpl
uniprot id: A0A8C5LB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

51337:Add1
gene id: 51337:Add1
uniprot id: A0A8C5KBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Membrane
messages: cytoskeleton

51337:Mb21d2
gene id: 51337:Mb21d2
uniprot id: A0A8C5LFR6
names: Similarity
messages: Belongs to the mab-21 family.

51337:Rpl19
gene id: 51337:Rpl19
uniprot id: A0A8C5LC15
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

51337:Dlx5
gene id: 51337:Dlx5
uniprot id: A0A8C5LBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

51337:LOC101604316
gene id: 51337:LOC101604316
uniprot id: A0A8C5KJF0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

51337:Cops4
gene id: 51337:Cops4
uniprot id: A0A8C5LCN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

51337:Pcnx4
gene id: 51337:Pcnx4
uniprot id: A0A8C5KAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

51337:Nkx2-2
gene id: 51337:Nkx2-2
uniprot id: A0A8C5LG39
names: Subcellular Location Annotation
messages: Nucleus

51337:Scamp2
gene id: 51337:Scamp2
uniprot id: A0A8C5NVC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

51337:Gje1
gene id: 51337:Gje1
uniprot id: A0A8C5KF82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Gabrb3
gene id: 51337:Gabrb3
uniprot id: A0A8C5L8J6
uniprot id: A0A8C5LAY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Gli1
gene id: 51337:Gli1
uniprot id: A0A8C5K5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

51337:Mon1b
gene id: 51337:Mon1b
uniprot id: A0A8C5L6Z0
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

51337:Gli3
gene id: 51337:Gli3
uniprot id: A0A8C5K5G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

51337:Pdp2
gene id: 51337:Pdp2
uniprot id: A0A8C5KKI9
names: Similarity
messages: Belongs to the PP2C family.

51337:Cnn2
gene id: 51337:Cnn2
uniprot id: A0A8C5K7S4
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

51337:Ppib
gene id: 51337:Ppib
uniprot id: A0A8C5P4E0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

51337:Acsm5
gene id: 51337:Acsm5
uniprot id: A0A8C5L1L5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Clic4
gene id: 51337:Clic4
uniprot id: A0A8C5P5Y9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

51337:Pigv
gene id: 51337:Pigv
uniprot id: A0A8C5L4Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

51337:Sdhaf3
gene id: 51337:Sdhaf3
uniprot id: A0A8C5K1T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

51337:Plxna4
gene id: 51337:Plxna4
uniprot id: A0A8C5K074
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:LOC101617706
gene id: 51337:LOC101617706
uniprot id: A0A8C5KYN2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

51337:Mfsd10
gene id: 51337:Mfsd10
uniprot id: A0A8C5KYV1
names: Subcellular Location Annotation
messages: Membrane

51337:Fam171b
gene id: 51337:Fam171b
uniprot id: A0A8C5NW73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

51337:Fmnl1
gene id: 51337:Fmnl1
uniprot id: A0A8C5L0R9
names: Similarity
messages: Belongs to the formin homology family.

51337:Drd2
gene id: 51337:Drd2
uniprot id: A0A8C5NXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

51337:Stim1
gene id: 51337:Stim1
uniprot id: A0A8C5K3Z5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Frk
gene id: 51337:Frk
uniprot id: A0A8C5KGG2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:Gcdh
gene id: 51337:Gcdh
uniprot id: A0A8C5P254
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

51337:Npbwr1
gene id: 51337:Npbwr1
uniprot id: A0A8C5KDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Dpagt1
gene id: 51337:Dpagt1
uniprot id: A0A8C5L6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101610436
gene id: 51337:LOC101610436
uniprot id: A0A8C5NXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

51337:Nup85
gene id: 51337:Nup85
uniprot id: A0A8C5NU69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

51337:Kif19
gene id: 51337:Kif19
uniprot id: A0A8C5LGW4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Tmem199
gene id: 51337:Tmem199
uniprot id: A0A8C5LJE7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Rc3h1
gene id: 51337:Rc3h1
uniprot id: A0A8C5L2U2
names: Subcellular Location Annotation
messages: P-body

51337:Pabir1
gene id: 51337:Pabir1
uniprot id: A0A8C5K8Q3
names: Similarity
messages: Belongs to the FAM122 family.

51337:Nup62cl
gene id: 51337:Nup62cl
uniprot id: A0A8C5L9K0
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

51337:Emc8
gene id: 51337:Emc8
uniprot id: A0A8C5K570
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

51337:Cntn1
gene id: 51337:Cntn1
uniprot id: A0A8C5P416
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

51337:Apoc1
gene id: 51337:Apoc1
uniprot id: A0A8C5KU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Secreted

51337:Hbe1
gene id: 51337:Hbe1
uniprot id: A0A8C5K7N3
names: Similarity
messages: Belongs to the globin family.

51337:Tafa5
gene id: 51337:Tafa5
uniprot id: A0A8C5LF19
names: Similarity
messages: Belongs to the TAFA family.

51337:Nox1
gene id: 51337:Nox1
uniprot id: A0A8C5KCL2
uniprot id: A0A8C5KF42
names: Subcellular Location Annotation
messages: Membrane

51337:Mpi
gene id: 51337:Mpi
uniprot id: A0A8C5K1C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

51337:LOC101616666
gene id: 51337:LOC101616666
uniprot id: A0A8C5P0B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Sgtb
gene id: 51337:Sgtb
uniprot id: A0A8C5JT73
names: Similarity
messages: Belongs to the SGT family.

51337:Lsm3
gene id: 51337:Lsm3
uniprot id: A0A8C5KW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

51337:LOC101606697
gene id: 51337:LOC101606697
uniprot id: A0A8C5L6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Esrrb
gene id: 51337:Esrrb
uniprot id: A0A8C5K485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

51337:Slc16a10
gene id: 51337:Slc16a10
uniprot id: A0A8C5L523
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101612739
gene id: 51337:LOC101612739
uniprot id: A0A8C5NVY5
names: Similarity
messages: Belongs to the actin family.

51337:Htr5a
gene id: 51337:Htr5a
uniprot id: A0A8C5KY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Dus4l
gene id: 51337:Dus4l
uniprot id: A0A8C5KMJ2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

51337:Slc6a3
gene id: 51337:Slc6a3
uniprot id: A0A8C5KZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

51337:Abi1
gene id: 51337:Abi1
uniprot id: A0A8C5L0A6
uniprot id: A0A8C5L282
uniprot id: A0A8C5L4D2
uniprot id: A0A8C5L4G5
uniprot id: A0A8C5P337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

51337:Phospho1
gene id: 51337:Phospho1
uniprot id: A0A8C5NWI0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

51337:Tshr
gene id: 51337:Tshr
uniprot id: A0A8C5LCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

51337:Mvd
gene id: 51337:Mvd
uniprot id: A0A8C5LJ81
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

51337:Cenpn
gene id: 51337:Cenpn
uniprot id: A0A8C5KQH0
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

51337:Steap4
gene id: 51337:Steap4
uniprot id: A0A8C5P105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

51337:Lpo
gene id: 51337:Lpo
uniprot id: A0A8C5LB29
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Secreted

51337:Nkx6-2
gene id: 51337:Nkx6-2
uniprot id: A0A8C5KZ45
names: Subcellular Location Annotation
messages: Nucleus

51337:Frzb
gene id: 51337:Frzb
uniprot id: A0A8C5NYL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

51337:LOC101596283
gene id: 51337:LOC101596283
uniprot id: A0A8C5NV24
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

51337:Nedd8
gene id: 51337:Nedd8
uniprot id: A0A8C5KHM1
names: Similarity
messages: Belongs to the ubiquitin family.

51337:Arrb1
gene id: 51337:Arrb1
uniprot id: A0A8C5JZ78
names: Similarity
messages: Belongs to the arrestin family.

51337:Ost4
gene id: 51337:Ost4
uniprot id: A0A8C5LBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Khdrbs1
gene id: 51337:Khdrbs1
uniprot id: A0A8C5KUD3
names: Similarity
messages: Belongs to the KHDRBS family.

51337:Znf174
gene id: 51337:Znf174
uniprot id: A0A8C5L158
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101604817
gene id: 51337:LOC101604817
uniprot id: A0A8C5KCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

51337:Uckl1
gene id: 51337:Uckl1
uniprot id: A0A8C5LCH9
names: Similarity
messages: Belongs to the uridine kinase family.

51337:Cetn1
gene id: 51337:Cetn1
uniprot id: A0A8C5K9W8
names: Similarity
messages: Belongs to the centrin family.

51337:Dgat1
gene id: 51337:Dgat1
uniprot id: A0A8C5KZH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

51337:Ccna1
gene id: 51337:Ccna1
uniprot id: A0A8C5P607
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

51337:Ighmbp2
gene id: 51337:Ighmbp2
uniprot id: A0A8C5LCH1
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

51337:Orai3
gene id: 51337:Orai3
uniprot id: A0A8C5L7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

51337:Sptlc2
gene id: 51337:Sptlc2
uniprot id: A0A8C5NYQ0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

51337:Lbh
gene id: 51337:Lbh
uniprot id: A0A8C5LKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

51337:Abracl
gene id: 51337:Abracl
uniprot id: A0A8C5K5U7
names: Similarity
messages: Belongs to the costars family.

51337:Cnot1
gene id: 51337:Cnot1
uniprot id: A0A8C5JZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

51337:Med27
gene id: 51337:Med27
uniprot id: A0A8C5P5Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

51337:Asb4
gene id: 51337:Asb4
uniprot id: A0A8C5KND1
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

51337:Rps13
gene id: 51337:Rps13
uniprot id: A0A8C5KN65
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

51337:Sar1a
gene id: 51337:Sar1a
uniprot id: A0A8C5KQ01
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

51337:Map2k5
gene id: 51337:Map2k5
uniprot id: A0A8C5LNG2
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Actc1
gene id: 51337:Actc1
uniprot id: A0A8C5NVA0
names: Similarity
messages: Belongs to the actin family.

51337:Spcs1
gene id: 51337:Spcs1
uniprot id: A0A8C5NWC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101597816
gene id: 51337:LOC101597816
uniprot id: A0A8C5NU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Prpf31
gene id: 51337:Prpf31
uniprot id: A0A8C5KRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

51337:Cbs
gene id: 51337:Cbs
uniprot id: A0A8C5L1W0
uniprot id: A0A8C5L6D2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

51337:C1H11orf49
gene id: 51337:C1H11orf49
uniprot id: A0A8C5NVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

51337:Wif1
gene id: 51337:Wif1
uniprot id: A0A8C5KWR4
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Dipk2b
gene id: 51337:Dipk2b
uniprot id: A0A8C5KA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

51337:Greb1
gene id: 51337:Greb1
uniprot id: A0A8C5L2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

51337:Midn
gene id: 51337:Midn
uniprot id: A0A8C5KGE4
uniprot id: A0A8C5KH83
names: Subcellular Location Annotation
messages: Nucleus

51337:Fam20a
gene id: 51337:Fam20a
uniprot id: A0A8C5L0H3
names: Similarity
messages: Belongs to the FAM20 family.

51337:Pigl
gene id: 51337:Pigl
uniprot id: A0A8C5NVG7
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

51337:Anp32a
gene id: 51337:Anp32a
uniprot id: A0A8C5P2Q9
names: Similarity
messages: Belongs to the ANP32 family.

51337:Kif22
gene id: 51337:Kif22
uniprot id: A0A8C5P4K7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Mcrip2
gene id: 51337:Mcrip2
uniprot id: A0A8C5KBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

51337:Ckm
gene id: 51337:Ckm
uniprot id: A0A8C5LAS9
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

51337:Psma3
gene id: 51337:Psma3
uniprot id: A0A8C5K2H0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

51337:Nme3
gene id: 51337:Nme3
uniprot id: A0A8C5KNM7
names: Similarity
messages: Belongs to the NDK family.

51337:LOC101617203
gene id: 51337:LOC101617203
uniprot id: A0A8C5P441
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

51337:LOC101597484
gene id: 51337:LOC101597484
uniprot id: A0A8C5KCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Pde4a
gene id: 51337:Pde4a
uniprot id: A0A8C5LE53
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Glyatl3
gene id: 51337:Glyatl3
uniprot id: A0A8C5KP84
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

51337:Rplp1
gene id: 51337:Rplp1
uniprot id: A0A8C5L334
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

51337:Ppp1r1a
gene id: 51337:Ppp1r1a
uniprot id: A0A8C5LEV8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

51337:Cdh13
gene id: 51337:Cdh13
uniprot id: A0A8C5KG01
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: By contrast to classical cadherins, homodimerization in trans is not mediated by cadherin EC1 domain strand-swapping, but instead through a homophilic adhesive interface which joins two elongated EC1-EC2 domains through a region near their Ca2+-binding sites to form a tetrahedral, X-like shape.
messages: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
messages: Cell membrane
messages: Membrane

51337:Pde7a
gene id: 51337:Pde7a
uniprot id: A0A8C5LDF6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Arfgef1
gene id: 51337:Arfgef1
uniprot id: A0A8C5LAK2
names: Subcellular Location Annotation
messages: Membrane
messages: perinuclear region
messages: trans-Golgi network

51337:Cdc42bpg
gene id: 51337:Cdc42bpg
uniprot id: A0A8C5K8L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm

51337:LOC101596976
gene id: 51337:LOC101596976
uniprot id: A0A8C5K8F3
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Theta family.
messages: Homodimer.

51337:Stx19
gene id: 51337:Stx19
uniprot id: A0A8C5KMW3
names: Similarity
messages: Belongs to the syntaxin family.

51337:Nfib
gene id: 51337:Nfib
uniprot id: A0A8C5KEN5
uniprot id: A0A8C5KJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

51337:Grpel1
gene id: 51337:Grpel1
uniprot id: A0A8C5KLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

51337:Mfge8
gene id: 51337:Mfge8
uniprot id: A0A8C5L552
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Gdf5
gene id: 51337:Gdf5
uniprot id: A0A8C5LFN3
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Cacng7
gene id: 51337:Cacng7
uniprot id: A0A8C5JZG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

51337:Rgs5
gene id: 51337:Rgs5
uniprot id: A0A8C5NZM3
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

51337:LOC101596259
gene id: 51337:LOC101596259
uniprot id: A0A8C5P288
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Fxyd6
gene id: 51337:Fxyd6
uniprot id: A0A8C5K9X1
names: Similarity
messages: Belongs to the FXYD family.

51337:Eif2s2
gene id: 51337:Eif2s2
uniprot id: A0A8C5KP29
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

51337:Fntb
gene id: 51337:Fntb
uniprot id: A0A8C5KXN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
messages: Heterodimer of FNTA and FNTB.

51337:Galk2
gene id: 51337:Galk2
uniprot id: A0A8C5NX82
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

51337:Sf3b5
gene id: 51337:Sf3b5
uniprot id: A0A8C5JYJ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

51337:Mul1
gene id: 51337:Mul1
uniprot id: A0A8C5KUS1
names: Subcellular Location Annotation
messages: Membrane

51337:Maml3
gene id: 51337:Maml3
uniprot id: A0A8C5LFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

51337:Igfbp6
gene id: 51337:Igfbp6
uniprot id: A0A8C5KI44
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Tbx15
gene id: 51337:Tbx15
uniprot id: A0A8C5KJ79
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Gdap1l1
gene id: 51337:Gdap1l1
uniprot id: A0A8C5NYW7
names: Similarity
messages: Belongs to the GST superfamily.

51337:Psat1
gene id: 51337:Psat1
uniprot id: A0A8C5K4I9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

51337:LOC101598116
gene id: 51337:LOC101598116
uniprot id: A0A8C5NUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

51337:Ctsc
gene id: 51337:Ctsc
uniprot id: A0A8C5KAS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

51337:Dolk
gene id: 51337:Dolk
uniprot id: A0A8C5KHQ3
names: Similarity
messages: Belongs to the polyprenol kinase family.

51337:Naa10
gene id: 51337:Naa10
uniprot id: A0A8C5LKR3
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

51337:Tnfsf12
gene id: 51337:Tnfsf12
uniprot id: A0A8C5K201
names: Similarity
messages: Belongs to the tumor necrosis factor family.

51337:Ndufb9
gene id: 51337:Ndufb9
uniprot id: A0A8C5P666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Adgrg1
gene id: 51337:Adgrg1
uniprot id: A0A8C5KLF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Secreted

51337:Tspan31
gene id: 51337:Tspan31
uniprot id: A0A8C5KGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Ago3
gene id: 51337:Ago3
uniprot id: A0A8C5KWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

51337:Zranb1
gene id: 51337:Zranb1
uniprot id: A0A8C5K7E4
names: Similarity
messages: Belongs to the peptidase C64 family.

51337:Myf6
gene id: 51337:Myf6
uniprot id: A0A8C5NX07
names: Subcellular Location Annotation
messages: Nucleus

51337:Nlrp3
gene id: 51337:Nlrp3
uniprot id: A0A8C5NW00
names: Similarity
messages: Belongs to the NLRP family.

51337:Rps6ka1
gene id: 51337:Rps6ka1
uniprot id: A0A8C5JV12
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

51337:Pla2g5
gene id: 51337:Pla2g5
uniprot id: A0A8C5KVI9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

51337:Cnot2
gene id: 51337:Cnot2
uniprot id: A0A8C5LCB9
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

51337:Auh
gene id: 51337:Auh
uniprot id: A0A8C5KP88
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

51337:Npm1
gene id: 51337:Npm1
uniprot id: A0A8C5KLY1
names: Similarity
messages: Belongs to the nucleoplasmin family.

51337:LOC101599821
gene id: 51337:LOC101599821
uniprot id: A0A8C5KBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101601862
gene id: 51337:LOC101601862
uniprot id: A0A8C5KIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

51337:Cacng5
gene id: 51337:Cacng5
uniprot id: A0A8C5K379
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

51337:Csnk1d
gene id: 51337:Csnk1d
uniprot id: A0A8C5K7M2
uniprot id: A0A8C5KCV1
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Cldn9
gene id: 51337:Cldn9
uniprot id: A0A8C5JWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Kcnh3
gene id: 51337:Kcnh3
uniprot id: A0A8C5L3B4
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

51337:Ugp2
gene id: 51337:Ugp2
uniprot id: A0A8C5KLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

51337:Il1f10
gene id: 51337:Il1f10
uniprot id: A0A8C5KKR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

51337:Ddx50
gene id: 51337:Ddx50
uniprot id: A0A8C5LL30
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

51337:Slc9a4
gene id: 51337:Slc9a4
uniprot id: A0A8C5KSR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Interacts with CHP1 and CHP2.
messages: Membrane

51337:Rhbdl3
gene id: 51337:Rhbdl3
uniprot id: A0A8C5K8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

51337:Tacr3
gene id: 51337:Tacr3
uniprot id: A0A8C5P504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101612122
gene id: 51337:LOC101612122
uniprot id: A0A8C5KK64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

51337:Smim8
gene id: 51337:Smim8
uniprot id: A0A8C5L3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

51337:Rpl36
gene id: 51337:Rpl36
uniprot id: A0A8C5P2X6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

51337:Camk1
gene id: 51337:Camk1
uniprot id: A0A8C5LN39
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:C12H9orf64
gene id: 51337:C12H9orf64
uniprot id: A0A8C5NTX5
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

51337:Acsm3
gene id: 51337:Acsm3
uniprot id: A0A8C5KTT6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Gpr3
gene id: 51337:Gpr3
uniprot id: A0A8C5L3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Ppp4c
gene id: 51337:Ppp4c
uniprot id: A0A8C5JWW8
names: Similarity
messages: Belongs to the PPP phosphatase family.

51337:Pex13
gene id: 51337:Pex13
uniprot id: A0A8C5L5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

51337:Farsb
gene id: 51337:Farsb
uniprot id: A0A8C5K0A6
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

51337:Irak4
gene id: 51337:Irak4
uniprot id: A0A8C5K1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

51337:Pappa2
gene id: 51337:Pappa2
uniprot id: A0A8C5KY86
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Fabp12
gene id: 51337:Fabp12
uniprot id: A0A8C5L8F1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:LOC101599691
gene id: 51337:LOC101599691
uniprot id: A0A8C5KAQ1
names: Subcellular Location Annotation
messages: Nucleus

51337:Fbxo25
gene id: 51337:Fbxo25
uniprot id: A0A8C5KLA2
names: Subcellular Location Annotation
messages: Nucleus

51337:Akap8l
gene id: 51337:Akap8l
uniprot id: A0A8C5KCL9
names: Similarity
messages: Belongs to the AKAP95 family.

51337:LOC101613186
gene id: 51337:LOC101613186
uniprot id: A0A8C5KLG8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Pde1b
gene id: 51337:Pde1b
uniprot id: A0A8C5KPU2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Nprl3
gene id: 51337:Nprl3
uniprot id: A0A8C5K9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

51337:Rpl27
gene id: 51337:Rpl27
uniprot id: A0A8C5KWV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

51337:Gsc
gene id: 51337:Gsc
uniprot id: A0A8C5KM19
names: Subcellular Location Annotation
messages: Nucleus

51337:Slc5a7
gene id: 51337:Slc5a7
uniprot id: A0A8C5P3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:St6gal1
gene id: 51337:St6gal1
uniprot id: A0A8C5K7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Uba52
gene id: 51337:Uba52
uniprot id: A0A8C5JZN4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

51337:Npsr1
gene id: 51337:Npsr1
uniprot id: A0A8C5P0E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

51337:Plp1
gene id: 51337:Plp1
uniprot id: A0A8C5NWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

51337:Pelo
gene id: 51337:Pelo
uniprot id: A0A8C5KRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: Interacts with PINK1, ABCE1 and CNOT4.
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

51337:Zdhhc14
gene id: 51337:Zdhhc14
uniprot id: A0A8C5K8A2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Gcsh
gene id: 51337:Gcsh
uniprot id: A0A8C5KTV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

51337:Slit3
gene id: 51337:Slit3
uniprot id: A0A8C5P2D5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:LOC101612288
gene id: 51337:LOC101612288
uniprot id: A0A8C5KPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Tax1bp3
gene id: 51337:Tax1bp3
uniprot id: A0A8C5KIC8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

51337:Rrad
gene id: 51337:Rrad
uniprot id: A0A8C5LAN0
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

51337:Stx5
gene id: 51337:Stx5
uniprot id: A0A8C5LE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

51337:LOC101611695
gene id: 51337:LOC101611695
uniprot id: A0A8C5KCS9
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

51337:Cat
gene id: 51337:Cat
uniprot id: A0A8C5KJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

51337:Cops3
gene id: 51337:Cops3
uniprot id: A0A8C5JZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

51337:Taf6
gene id: 51337:Taf6
uniprot id: A0A8C5K1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

51337:LOC101604847
gene id: 51337:LOC101604847
uniprot id: A0A8C5JYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

51337:Mindy3
gene id: 51337:Mindy3
uniprot id: A0A8C5JWU7
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

51337:Tomm20
gene id: 51337:Tomm20
uniprot id: A0A8C5KIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:LOC101617236
gene id: 51337:LOC101617236
uniprot id: A0A8C5K7C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Grin2c
gene id: 51337:Grin2c
uniprot id: A0A8C5LJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

51337:Amy2b
gene id: 51337:Amy2b
uniprot id: A0A8C5LIM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

51337:Myo1c
gene id: 51337:Myo1c
uniprot id: A0A8C5KXQ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Eipr1
gene id: 51337:Eipr1
uniprot id: A0A8C5L0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

51337:Gpc3
gene id: 51337:Gpc3
uniprot id: A0A8C5K190
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

51337:Zdhhc22
gene id: 51337:Zdhhc22
uniprot id: A0A8C5LJH2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Snap47
gene id: 51337:Snap47
uniprot id: A0A8C5LI51
names: Similarity
messages: Belongs to the SVAP1 family.

51337:Ctnnbl1
gene id: 51337:Ctnnbl1
uniprot id: A0A8C5LJX4
names: Subcellular Location Annotation
messages: Nucleus

51337:Myoz2
gene id: 51337:Myoz2
uniprot id: A0A8C5KXJ2
names: Similarity
messages: Belongs to the myozenin family.

51337:Aldh1l1
gene id: 51337:Aldh1l1
uniprot id: A0A8C5KCR0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

51337:Med24
gene id: 51337:Med24
uniprot id: A0A8C5JYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

51337:Ier3ip1
gene id: 51337:Ier3ip1
uniprot id: A0A8C5NW44
names: Similarity
messages: Belongs to the YOS1 family.

51337:Fgf17
gene id: 51337:Fgf17
uniprot id: A0A8C5P1V1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Gpr107
gene id: 51337:Gpr107
uniprot id: A0A8C5NXH6
names: Subcellular Location Annotation
messages: Membrane

51337:Arrdc3
gene id: 51337:Arrdc3
uniprot id: A0A8C5L7D4
names: Similarity
messages: Belongs to the arrestin family.

51337:LOC101595569
gene id: 51337:LOC101595569
uniprot id: A0A8C5KJG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

51337:Atp6v0b
gene id: 51337:Atp6v0b
uniprot id: A0A8C5K4K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

51337:Calhm3
gene id: 51337:Calhm3
uniprot id: A0A8C5LBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

51337:Gchfr
gene id: 51337:Gchfr
uniprot id: A0A8C5K1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

51337:Phpt1
gene id: 51337:Phpt1
uniprot id: A0A8C5LDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

51337:Umod
gene id: 51337:Umod
uniprot id: A0A8C5KRF2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Cell membrane
messages: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium membrane

51337:Bmp5
gene id: 51337:Bmp5
uniprot id: A0A8C5L1Y9
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Polr2l
gene id: 51337:Polr2l
uniprot id: A0A8C5K960
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

51337:Slc17a7
gene id: 51337:Slc17a7
uniprot id: A0A8C5JXZ1
names: Subcellular Location Annotation
messages: Membrane

51337:Myh9
gene id: 51337:Myh9
uniprot id: A0A8C5NVN8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Galnt14
gene id: 51337:Galnt14
uniprot id: A0A8C5L6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Phkg2
gene id: 51337:Phkg2
uniprot id: A0A8C5K1T7
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

51337:Aldoc
gene id: 51337:Aldoc
uniprot id: A0A8C5KLT3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

51337:Hmces
gene id: 51337:Hmces
uniprot id: A0A8C5KHK7
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

51337:Map2k1
gene id: 51337:Map2k1
uniprot id: A0A8C5L7Z6
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Ckmt2
gene id: 51337:Ckmt2
uniprot id: A0A8C5KNQ1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

51337:Med21
gene id: 51337:Med21
uniprot id: A0A8C5KQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

51337:LOC101606158
gene id: 51337:LOC101606158
uniprot id: A0A8C5LJN7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Pex3
gene id: 51337:Pex3
uniprot id: A0A8C5NZQ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

51337:Arpc1a
gene id: 51337:Arpc1a
uniprot id: A0A8C5KAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

51337:LOC101601223
gene id: 51337:LOC101601223
uniprot id: A0A8C5L5H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Slc66a3
gene id: 51337:Slc66a3
uniprot id: A0A8C5JYB7
names: Subcellular Location Annotation
messages: Membrane

51337:Inpp5a
gene id: 51337:Inpp5a
uniprot id: A0A8C5KV98
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

51337:Pin4
gene id: 51337:Pin4
uniprot id: A0A8C5P488
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

51337:Cdnf
gene id: 51337:Cdnf
uniprot id: A0A8C5KU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

51337:Cul4a
gene id: 51337:Cul4a
uniprot id: A0A8C5P4N0
names: Similarity
messages: Belongs to the cullin family.

51337:Akap4
gene id: 51337:Akap4
uniprot id: A0A8C5KDH5
names: Similarity
messages: Belongs to the AKAP110 family.

51337:Ehd2
gene id: 51337:Ehd2
uniprot id: A0A8C5K8U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

51337:Pex16
gene id: 51337:Pex16
uniprot id: A0A8C5LGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

51337:Chrm5
gene id: 51337:Chrm5
uniprot id: A0A8C5KG09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

51337:Actl7a
gene id: 51337:Actl7a
uniprot id: A0A8C5K3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

51337:Hps6
gene id: 51337:Hps6
uniprot id: A0A8C5KAC7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

51337:LOC101594980
gene id: 51337:LOC101594980
uniprot id: A0A8C5NYI1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Hoxd12
gene id: 51337:Hoxd12
uniprot id: A0A8C5KPV8
names: Subcellular Location Annotation
messages: Nucleus

51337:Rnasek
gene id: 51337:Rnasek
uniprot id: A0A8C5KWX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

51337:Fars2
gene id: 51337:Fars2
uniprot id: A0A8C5K0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

51337:Fzd10
gene id: 51337:Fzd10
uniprot id: A0A8C5KBH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

51337:Edem3
gene id: 51337:Edem3
uniprot id: A0A8C5KNW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

51337:Capn2
gene id: 51337:Capn2
uniprot id: A0A8C5KBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

51337:Cplx4
gene id: 51337:Cplx4
uniprot id: A0A8C5KS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

51337:Vegfc
gene id: 51337:Vegfc
uniprot id: A0A8C5LL41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

51337:Cygb
gene id: 51337:Cygb
uniprot id: A0A8C5KD92
names: Similarity
messages: Belongs to the globin family.

51337:Chst7
gene id: 51337:Chst7
uniprot id: A0A8C5KI79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

51337:Ribc2
gene id: 51337:Ribc2
uniprot id: A0A8C5L723
names: Similarity
messages: Belongs to the RIB43A family.

51337:Rps3
gene id: 51337:Rps3
uniprot id: A0A8C5L1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: nucleolus
messages: spindle

51337:Vti1a
gene id: 51337:Vti1a
uniprot id: A0A8C5P3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

51337:Irx3
gene id: 51337:Irx3
uniprot id: A0A8C5P498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

51337:Myh2
gene id: 51337:Myh2
uniprot id: A0A8C5P5R8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Ttc39c
gene id: 51337:Ttc39c
uniprot id: A0A8C5L2S5
names: Similarity
messages: Belongs to the TTC39 family.

51337:Ssr4
gene id: 51337:Ssr4
uniprot id: A0A8C5KYS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

51337:Kcna4
gene id: 51337:Kcna4
uniprot id: A0A8C5KXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

51337:F13a1
gene id: 51337:F13a1
uniprot id: A0A8C5NU92
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

51337:LOC101611427
gene id: 51337:LOC101611427
uniprot id: A0A8C5K3K4
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

51337:Tufm
gene id: 51337:Tufm
uniprot id: A0A8C5K9P3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

51337:Bmpr1b
gene id: 51337:Bmpr1b
uniprot id: A0A8C5KCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

51337:Hbz
gene id: 51337:Hbz
uniprot id: A0A8C5K7K3
names: Similarity
messages: Belongs to the globin family.

51337:Ttyh2
gene id: 51337:Ttyh2
uniprot id: A0A8C5NUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

51337:Qprt
gene id: 51337:Qprt
uniprot id: A0A8C5L236
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

51337:Baz2a
gene id: 51337:Baz2a
uniprot id: A0A8C5K766
names: Similarity
messages: Belongs to the WAL family.

51337:Macir
gene id: 51337:Macir
uniprot id: A0A8C5K289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

51337:Slc8a1
gene id: 51337:Slc8a1
uniprot id: A0A8C5KQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

51337:Dkk2
gene id: 51337:Dkk2
uniprot id: A0A8C5P1A6
names: Similarity
messages: Belongs to the dickkopf family.

51337:Slc29a2
gene id: 51337:Slc29a2
uniprot id: A0A8C5L4E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

51337:B4gat1
gene id: 51337:B4gat1
uniprot id: A0A8C5KWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Rpl13
gene id: 51337:Rpl13
uniprot id: A0A8C5KNV8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

51337:F11r
gene id: 51337:F11r
uniprot id: A0A8C5KJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

51337:Mmp20
gene id: 51337:Mmp20
uniprot id: A0A8C5P338
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:Nap1l1
gene id: 51337:Nap1l1
uniprot id: A0A8C5LIE9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

51337:Eif5a
gene id: 51337:Eif5a
uniprot id: A0A8C5KB36
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

51337:Pgm2l1
gene id: 51337:Pgm2l1
uniprot id: A0A8C5LC31
names: Similarity
messages: Belongs to the phosphohexose mutase family.

51337:Clvs2
gene id: 51337:Clvs2
uniprot id: A0A8C5LHR1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

51337:Nup133
gene id: 51337:Nup133
uniprot id: A0A8C5LN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

51337:Utp11
gene id: 51337:Utp11
uniprot id: A0A8C5LH66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

51337:Ssbp1
gene id: 51337:Ssbp1
uniprot id: A0A8C5KT12
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

51337:Slc27a6
gene id: 51337:Slc27a6
uniprot id: A0A8C5L822
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:LOC101607573
gene id: 51337:LOC101607573
uniprot id: A0A8C5NYX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

51337:Hyls1
gene id: 51337:Hyls1
uniprot id: A0A8C5NXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

51337:LOC101615836
gene id: 51337:LOC101615836
uniprot id: A0A8C5LIN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

51337:Vps51
gene id: 51337:Vps51
uniprot id: A0A8C5K2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

51337:Meox2
gene id: 51337:Meox2
uniprot id: A0A8C5K3S8
names: Subcellular Location Annotation
messages: Nucleus

51337:Cacng3
gene id: 51337:Cacng3
uniprot id: A0A8C5LJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

51337:Slc25a11
gene id: 51337:Slc25a11
uniprot id: A0A8C5L4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Folr1
gene id: 51337:Folr1
uniprot id: A0A8C5L4X7
names: Similarity
messages: Belongs to the folate receptor family.

51337:Nr1h4
gene id: 51337:Nr1h4
uniprot id: A0A8C5KWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

51337:Psmb4
gene id: 51337:Psmb4
uniprot id: A0A8C5KG68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

51337:Lhx2
gene id: 51337:Lhx2
uniprot id: A0A8C5KU13
names: Subcellular Location Annotation
messages: Nucleus

51337:Chm
gene id: 51337:Chm
uniprot id: A0A8C5KBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

51337:Apln
gene id: 51337:Apln
uniprot id: A0A8C5LJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

51337:Plag1
gene id: 51337:Plag1
uniprot id: A0A8C5K2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

51337:Fam133b
gene id: 51337:Fam133b
uniprot id: A0A8C5LCS2
names: Similarity
messages: Belongs to the FAM133 family.

51337:Chd8
gene id: 51337:Chd8
uniprot id: A0A8C5JU96
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.
messages: Interacts with p53/TP53, histone H1, CTNNB1, CTCF and PIAS3. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with CHD7. Interacts with FAM124B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sumoylated.

51337:Ets1
gene id: 51337:Ets1
uniprot id: A0A8C5KD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

51337:Arap2
gene id: 51337:Arap2
uniprot id: A0A8C5K6A0
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Ccr7
gene id: 51337:Ccr7
uniprot id: A0A8C5K1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Gstz1
gene id: 51337:Gstz1
uniprot id: A0A8C5K5Z9
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

51337:Utp14a
gene id: 51337:Utp14a
uniprot id: A0A8C5LGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

51337:Phospho2
gene id: 51337:Phospho2
uniprot id: A0A8C5JZ92
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

51337:Fgf16
gene id: 51337:Fgf16
uniprot id: A0A8C5L1H3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Med4
gene id: 51337:Med4
uniprot id: A0A8C5K8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

51337:Cdk9
gene id: 51337:Cdk9
uniprot id: A0A8C5KTJ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:LOC101612018
gene id: 51337:LOC101612018
uniprot id: A0A8C5K0I4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

51337:Pdgfc
gene id: 51337:Pdgfc
uniprot id: A0A8C5L1W2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Serinc1
gene id: 51337:Serinc1
uniprot id: A0A8C5L0Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

51337:Rbck1
gene id: 51337:Rbck1
uniprot id: A0A8C5KNX7
names: Similarity
messages: Belongs to the RBR family.

51337:LOC101599664
gene id: 51337:LOC101599664
uniprot id: A0A8C5KN70
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

51337:Pigs
gene id: 51337:Pigs
uniprot id: A0A8C5L3W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Apcs
gene id: 51337:Apcs
uniprot id: A0A8C5KK36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

51337:LOC101614194
gene id: 51337:LOC101614194
uniprot id: A0A8C5LEN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

51337:Igfbp1
gene id: 51337:Igfbp1
uniprot id: A0A8C5KF98
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Itm2b
gene id: 51337:Itm2b
uniprot id: A0A8C5K8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

51337:Gjd2
gene id: 51337:Gjd2
uniprot id: A0A8C5K5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Sh3gl1
gene id: 51337:Sh3gl1
uniprot id: A0A8C5LFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
messages: Membrane

51337:Papss1
gene id: 51337:Papss1
uniprot id: A0A8C5KVE0
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

51337:Musk
gene id: 51337:Musk
uniprot id: A0A8C5LCR1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Myh14
gene id: 51337:Myh14
uniprot id: A0A8C5LAA8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Ndnf
gene id: 51337:Ndnf
uniprot id: A0A8C5LHQ3
names: Subcellular Location Annotation
messages: Secreted

51337:Nob1
gene id: 51337:Nob1
uniprot id: A0A8C5KLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

51337:B3galnt2
gene id: 51337:B3galnt2
uniprot id: A0A8C5LFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Eya1
gene id: 51337:Eya1
uniprot id: A0A8C5LG06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

51337:Slc25a35
gene id: 51337:Slc25a35
uniprot id: A0A8C5KY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Mcf2l
gene id: 51337:Mcf2l
uniprot id: A0A8C5K5R6
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Ube2i
gene id: 51337:Ube2i
uniprot id: A0A8C5L3B5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Stc2
gene id: 51337:Stc2
uniprot id: A0A8C5KHD1
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

51337:Lrp10
gene id: 51337:Lrp10
uniprot id: A0A8C5K820
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101596272
gene id: 51337:LOC101596272
uniprot id: A0A8C5K543
names: Similarity
messages: Belongs to the globin family.

51337:Map2k6
gene id: 51337:Map2k6
uniprot id: A0A8C5JY93
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Gpr137
gene id: 51337:Gpr137
uniprot id: A0A8C5P241
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

51337:Plod1
gene id: 51337:Plod1
uniprot id: A0A8C5NYU5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

51337:Tomm22
gene id: 51337:Tomm22
uniprot id: A0A8C5KEI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

51337:Loxl2
gene id: 51337:Loxl2
uniprot id: A0A8C5K8K1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

51337:Foxf1
gene id: 51337:Foxf1
uniprot id: A0A8C5P1E3
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101614366
gene id: 51337:LOC101614366
uniprot id: A0A8C5NYG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Siah3
gene id: 51337:Siah3
uniprot id: A0A8C5L5E3
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

51337:LOC101595391
gene id: 51337:LOC101595391
uniprot id: A0A8C5NUR6
names: Similarity
messages: Belongs to the ATG8 family.

51337:Cdca5
gene id: 51337:Cdca5
uniprot id: A0A8C5LLD5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

51337:Lamtor1
gene id: 51337:Lamtor1
uniprot id: A0A8C5NX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

51337:Sesn3
gene id: 51337:Sesn3
uniprot id: A0A8C5L4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

51337:Dctn6
gene id: 51337:Dctn6
uniprot id: A0A8C5K602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

51337:Eif3b
gene id: 51337:Eif3b
uniprot id: A0A8C5KIC3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with UPF2. Interacts with METTL3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: The RRM domain mediates interaction with EIF3J.

51337:Rbfox2
gene id: 51337:Rbfox2
uniprot id: A0A8C5KQZ9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

51337:Jph3
gene id: 51337:Jph3
uniprot id: A0A8C5LIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

51337:Liph
gene id: 51337:Liph
uniprot id: A0A8C5L560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

51337:Eed
gene id: 51337:Eed
uniprot id: A0A8C5KQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

51337:LOC101616850
gene id: 51337:LOC101616850
uniprot id: A0A8C5KA16
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

51337:Miox
gene id: 51337:Miox
uniprot id: A0A8C5K2Q8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

51337:Spdl1
gene id: 51337:Spdl1
uniprot id: A0A8C5KD67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

51337:Timm17a
gene id: 51337:Timm17a
uniprot id: A0A8C5P130
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Nkx2-5
gene id: 51337:Nkx2-5
uniprot id: A0A8C5KP93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

51337:Degs2
gene id: 51337:Degs2
uniprot id: A0A8C5K3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Dnase2b
gene id: 51337:Dnase2b
uniprot id: A0A8C5K5H4
names: Similarity
messages: Belongs to the DNase II family.

51337:Gadd45a
gene id: 51337:Gadd45a
uniprot id: A0A8C5P0M8
names: Similarity
messages: Belongs to the GADD45 family.

51337:Avpr1a
gene id: 51337:Avpr1a
uniprot id: A0A8C5KV29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

51337:Srd5a1
gene id: 51337:Srd5a1
uniprot id: A0A8C5K6W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

51337:Cdk16
gene id: 51337:Cdk16
uniprot id: A0A8C5LGH4
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Erbin
gene id: 51337:Erbin
uniprot id: A0A8C5NXU5
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

51337:LOC101612445
gene id: 51337:LOC101612445
uniprot id: A0A8C5NVY5
names: Similarity
messages: Belongs to the actin family.

51337:LOC101612756
gene id: 51337:LOC101612756
uniprot id: A0A8C5NVE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Matk
gene id: 51337:Matk
uniprot id: A0A8C5KW01
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:Copz1
gene id: 51337:Copz1
uniprot id: A0A8C5LEV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

51337:Upp1
gene id: 51337:Upp1
uniprot id: A0A8C5K0U7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

51337:Dpysl3
gene id: 51337:Dpysl3
uniprot id: A0A8C5L835
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

51337:LOC101618223
gene id: 51337:LOC101618223
uniprot id: A0A8C5LDT2
names: Similarity
messages: Belongs to the 3-beta-HSD family.

51337:Nsun5
gene id: 51337:Nsun5
uniprot id: A0A8C5KC05
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

51337:Akr1d1
gene id: 51337:Akr1d1
uniprot id: A0A8C5LFC5
names: Similarity
messages: Belongs to the aldo/keto reductase family.

51337:Kcnk13
gene id: 51337:Kcnk13
uniprot id: A0A8C5L0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

51337:S100b
gene id: 51337:S100b
uniprot id: A0A8C5KIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

51337:LOC101597892
gene id: 51337:LOC101597892
uniprot id: A0A8C5LHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

51337:Slc25a4
gene id: 51337:Slc25a4
uniprot id: A0A8C5NU41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

51337:Tgfb3
gene id: 51337:Tgfb3
uniprot id: A0A8C5LIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

51337:Tpm3
gene id: 51337:Tpm3
uniprot id: A0A8C5KU93
uniprot id: A0A8C5KW41
uniprot id: A0A8C5KYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

51337:Slc26a2
gene id: 51337:Slc26a2
uniprot id: A0A8C5NX10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

51337:Ppp1r1c
gene id: 51337:Ppp1r1c
uniprot id: A0A8C5K210
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

51337:Hmgb2
gene id: 51337:Hmgb2
uniprot id: A0A8C5KAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

51337:Slc6a11
gene id: 51337:Slc6a11
uniprot id: A0A8C5K679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:Sf3a3
gene id: 51337:Sf3a3
uniprot id: A0A8C5KHJ4
names: Similarity
messages: Belongs to the SF3A3 family.

51337:Ppp2r2b
gene id: 51337:Ppp2r2b
uniprot id: A0A8C5KKF7
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

51337:Ms4a6a
gene id: 51337:Ms4a6a
uniprot id: A0A8C5KS07
names: Function
names: Similarity
messages: Belongs to the MS4A family.
messages: May be involved in signal transduction as a component of a multimeric receptor complex.

51337:Cuta
gene id: 51337:Cuta
uniprot id: A0A8C5LFV1
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

51337:Slc17a5
gene id: 51337:Slc17a5
uniprot id: A0A8C5KGW1
names: Subcellular Location Annotation
messages: Membrane

51337:Cxxc5
gene id: 51337:Cxxc5
uniprot id: A0A8C5LDU6
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Mthfd1
gene id: 51337:Mthfd1
uniprot id: A0A8C5L0T3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

51337:LOC101598452
gene id: 51337:LOC101598452
uniprot id: A0A8C5JZJ3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Hebp2
gene id: 51337:Hebp2
uniprot id: A0A8C5NW76
names: Similarity
messages: Belongs to the HEBP family.

51337:Tomt
gene id: 51337:Tomt
uniprot id: A0A8C5JXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

51337:Vars2
gene id: 51337:Vars2
uniprot id: A0A8C5NWY2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Hs6st3
gene id: 51337:Hs6st3
uniprot id: A0A8C5LGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

51337:Ppp1r9b
gene id: 51337:Ppp1r9b
uniprot id: A0A8C5K280
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Bmp7
gene id: 51337:Bmp7
uniprot id: A0A8C5P2T6
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Tmem9b
gene id: 51337:Tmem9b
uniprot id: A0A8C5KTW9
names: Similarity
messages: Belongs to the TMEM9 family.

51337:Pop5
gene id: 51337:Pop5
uniprot id: A0A8C5JXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

51337:Ippk
gene id: 51337:Ippk
uniprot id: A0A8C5LAW4
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

51337:Fgf14
gene id: 51337:Fgf14
uniprot id: A0A8C5KFU5
uniprot id: A0A8C5KJC8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Vti1b
gene id: 51337:Vti1b
uniprot id: A0A8C5P4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

51337:Atxn1
gene id: 51337:Atxn1
uniprot id: A0A8C5NUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

51337:Amt
gene id: 51337:Amt
uniprot id: A0A8C5K2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

51337:Tspan12
gene id: 51337:Tspan12
uniprot id: A0A8C5K2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Arrdc2
gene id: 51337:Arrdc2
uniprot id: A0A8C5LGC8
names: Similarity
messages: Belongs to the arrestin family.

51337:Myog
gene id: 51337:Myog
uniprot id: A0A8C5KJR6
names: Subcellular Location Annotation
messages: Nucleus

51337:Epg5
gene id: 51337:Epg5
uniprot id: A0A8C5K1Z5
names: Similarity
messages: Belongs to the EPG5 family.

51337:Rps15a
gene id: 51337:Rps15a
uniprot id: A0A8C5LA40
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

51337:Kcnj9
gene id: 51337:Kcnj9
uniprot id: A0A8C5JWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

51337:LOC101607795
gene id: 51337:LOC101607795
uniprot id: A0A8C5KX25
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Pofut2
gene id: 51337:Pofut2
uniprot id: A0A8C5KUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 68 family.
messages: Endoplasmic reticulum

51337:Gtpbp4
gene id: 51337:Gtpbp4
uniprot id: A0A8C5NWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

51337:Tmed6
gene id: 51337:Tmed6
uniprot id: A0A8C5NW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Pla2g2c
gene id: 51337:Pla2g2c
uniprot id: A0A8C5KFV7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

51337:Psmb2
gene id: 51337:Psmb2
uniprot id: A0A8C5KSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

51337:LOC101613638
gene id: 51337:LOC101613638
uniprot id: A0A8C5P0K0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

51337:Bloc1s5
gene id: 51337:Bloc1s5
uniprot id: A0A8C5LAF2
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

51337:Acp5
gene id: 51337:Acp5
uniprot id: A0A8C5K2A1
names: Cofactor
messages: Binds 2 iron ions per subunit.

51337:Atrnl1
gene id: 51337:Atrnl1
uniprot id: A0A8C5L4W2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Slit1
gene id: 51337:Slit1
uniprot id: A0A8C5LFN8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Trappc3
gene id: 51337:Trappc3
uniprot id: A0A8C5L8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

51337:Asic3
gene id: 51337:Asic3
uniprot id: A0A8C5LGG5
names: Subcellular Location Annotation
messages: Membrane

51337:Trim45
gene id: 51337:Trim45
uniprot id: A0A8C5NVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

51337:Hoxd10
gene id: 51337:Hoxd10
uniprot id: A0A8C5NXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

51337:F7
gene id: 51337:F7
uniprot id: A0A8C5LN73
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
messages: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Flcn
gene id: 51337:Flcn
uniprot id: A0A8C5KK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

51337:Drgx
gene id: 51337:Drgx
uniprot id: A0A8C5NZQ4
names: Subcellular Location Annotation
messages: Nucleus

51337:Ddx52
gene id: 51337:Ddx52
uniprot id: A0A8C5LCN6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

51337:Kcnc4
gene id: 51337:Kcnc4
uniprot id: A0A8C5L8M6
names: Subcellular Location Annotation
messages: Membrane

51337:Slit2
gene id: 51337:Slit2
uniprot id: A0A8C5KY40
uniprot id: A0A8C5L1M3
uniprot id: A0A8C5L1Z1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:St8sia3
gene id: 51337:St8sia3
uniprot id: A0A8C5KSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Dnajc22
gene id: 51337:Dnajc22
uniprot id: A0A8C5P0P9
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

51337:Cenpa
gene id: 51337:Cenpa
uniprot id: A0A8C5KQ62
names: Similarity
messages: Belongs to the histone H3 family.

51337:Myt1
gene id: 51337:Myt1
uniprot id: A0A8C5KCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

51337:Bola3
gene id: 51337:Bola3
uniprot id: A0A8C5KJY9
names: Similarity
messages: Belongs to the BolA/IbaG family.

51337:Gmppb
gene id: 51337:Gmppb
uniprot id: A0A8C5K7T5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

51337:Csnk2b
gene id: 51337:Csnk2b
uniprot id: A0A8C5KIW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

51337:St18
gene id: 51337:St18
uniprot id: A0A8C5L311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

51337:Efna4
gene id: 51337:Efna4
uniprot id: A0A8C5KDG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:LOC101617587
gene id: 51337:LOC101617587
uniprot id: A0A8C5P2W0
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

51337:Gng14
gene id: 51337:Gng14
uniprot id: A0A8C5L6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:Stmn4
gene id: 51337:Stmn4
uniprot id: A0A8C5K8Z5
names: Similarity
messages: Belongs to the stathmin family.

51337:LOC101605257
gene id: 51337:LOC101605257
uniprot id: A0A8C5NZK0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:Ppil2
gene id: 51337:Ppil2
uniprot id: A0A8C5LEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

51337:Emx2
gene id: 51337:Emx2
uniprot id: A0A8C5KQB0
names: Subcellular Location Annotation
messages: Nucleus

51337:Gtf2h4
gene id: 51337:Gtf2h4
uniprot id: A0A8C5KLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

51337:Mvb12a
gene id: 51337:Mvb12a
uniprot id: A0A8C5L693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

51337:Isl1
gene id: 51337:Isl1
uniprot id: A0A8C5KTJ3
names: Subcellular Location Annotation
messages: Nucleus

51337:Acmsd
gene id: 51337:Acmsd
uniprot id: A0A8C5KRW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

51337:Csk
gene id: 51337:Csk
uniprot id: A0A8C5K5U8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:Scg5
gene id: 51337:Scg5
uniprot id: A0A8C5NYW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

51337:Peli1
gene id: 51337:Peli1
uniprot id: A0A8C5JWR7
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

51337:Scgb1a1
gene id: 51337:Scgb1a1
uniprot id: A0A8C5KIT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

51337:Arf6
gene id: 51337:Arf6
uniprot id: A0A8C5KRF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

51337:Scrn3
gene id: 51337:Scrn3
uniprot id: A0A8C5L4I9
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

51337:Ndufs4
gene id: 51337:Ndufs4
uniprot id: A0A8C5KJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

51337:Shbg
gene id: 51337:Shbg
uniprot id: A0A8C5KN53
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Dbr1
gene id: 51337:Dbr1
uniprot id: A0A8C5KWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

51337:Cpxm2
gene id: 51337:Cpxm2
uniprot id: A0A8C5LJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

51337:Cog3
gene id: 51337:Cog3
uniprot id: A0A8C5KZJ8
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

51337:Serpind1
gene id: 51337:Serpind1
uniprot id: A0A8C5KFY4
names: Similarity
messages: Belongs to the serpin family.

51337:LOC101600997
gene id: 51337:LOC101600997
uniprot id: A0A8C5KML4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Secreted

51337:Ahcyl1
gene id: 51337:Ahcyl1
uniprot id: A0A8C5KZT9
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

51337:Kcnj2
gene id: 51337:Kcnj2
uniprot id: A0A8C5L7I7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Homomultimeric and heteromultimeric association with KCNJ4/Kir2.3. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking.
messages: Membrane

51337:Msl3
gene id: 51337:Msl3
uniprot id: A0A8C5K5H2
names: Subcellular Location Annotation
messages: Nucleus

51337:Ndrg1
gene id: 51337:Ndrg1
uniprot id: A0A8C5K461
names: Similarity
messages: Belongs to the NDRG family.

51337:Trpm8
gene id: 51337:Trpm8
uniprot id: A0A8C5LCA2
names: Subcellular Location Annotation
messages: Membrane

51337:Bpnt1
gene id: 51337:Bpnt1
uniprot id: A0A8C5P3T4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

51337:Cdipt
gene id: 51337:Cdipt
uniprot id: A0A8C5KEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

51337:LOC101601530
gene id: 51337:LOC101601530
uniprot id: A0A8C5L1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

51337:Chd5
gene id: 51337:Chd5
uniprot id: A0A8C5L289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

51337:Pus10
gene id: 51337:Pus10
uniprot id: A0A8C5K443
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

51337:Hm13
gene id: 51337:Hm13
uniprot id: A0A8C5NXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

51337:Sdhaf2
gene id: 51337:Sdhaf2
uniprot id: A0A8C5L5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

51337:Crbn
gene id: 51337:Crbn
uniprot id: A0A8C5KBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

51337:LOC101616564
gene id: 51337:LOC101616564
uniprot id: A0A8C5KUT8
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Pld1
gene id: 51337:Pld1
uniprot id: A0A8C5KRK9
names: Similarity
messages: Belongs to the phospholipase D family.

51337:LOC101594821
gene id: 51337:LOC101594821
uniprot id: A0A8C5KWH4
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

51337:Fto
gene id: 51337:Fto
uniprot id: A0A8C5KK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

51337:Triqk
gene id: 51337:Triqk
uniprot id: A0A8C5KX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Rcan1
gene id: 51337:Rcan1
uniprot id: A0A8C5L532
names: Similarity
messages: Belongs to the RCAN family.

51337:Eif3h
gene id: 51337:Eif3h
uniprot id: A0A8C5KVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

51337:Lhfpl4
gene id: 51337:Lhfpl4
uniprot id: A0A8C5L6B2
names: Subcellular Location Annotation
messages: Membrane

51337:Reep4
gene id: 51337:Reep4
uniprot id: A0A8C5KA90
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Hacl1
gene id: 51337:Hacl1
uniprot id: A0A8C5P232
names: Similarity
messages: Belongs to the TPP enzyme family.

51337:Upf2
gene id: 51337:Upf2
uniprot id: A0A8C5K287
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Myadml2
gene id: 51337:Myadml2
uniprot id: A0A8C5K2E5
names: Subcellular Location Annotation
messages: Membrane

51337:Ppp2r5e
gene id: 51337:Ppp2r5e
uniprot id: A0A8C5L3X2
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

51337:Pcnx3
gene id: 51337:Pcnx3
uniprot id: A0A8C5KHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

51337:Dyrk1b
gene id: 51337:Dyrk1b
uniprot id: A0A8C5L569
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

51337:Hmgb3
gene id: 51337:Hmgb3
uniprot id: A0A8C5P401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

51337:Qtrt1
gene id: 51337:Qtrt1
uniprot id: A0A8C5KJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

51337:Tspan1
gene id: 51337:Tspan1
uniprot id: A0A8C5KZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Dok6
gene id: 51337:Dok6
uniprot id: A0A8C5KVX1
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

51337:Eif2b5
gene id: 51337:Eif2b5
uniprot id: A0A8C5JZ03
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

51337:Kcnh6
gene id: 51337:Kcnh6
uniprot id: A0A8C5KFW5
names: Subcellular Location Annotation
messages: Membrane

51337:Thap1
gene id: 51337:Thap1
uniprot id: A0A8C5JWE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

51337:Dynlt1
gene id: 51337:Dynlt1
uniprot id: A0A8C5P3R6
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

51337:Rars1
gene id: 51337:Rars1
uniprot id: A0A8C5P3E7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:St3gal1
gene id: 51337:St3gal1
uniprot id: A0A8C5LEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Slc20a1
gene id: 51337:Slc20a1
uniprot id: A0A8C5NYU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

51337:Riok3
gene id: 51337:Riok3
uniprot id: A0A8C5LDT4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

51337:Gpr20
gene id: 51337:Gpr20
uniprot id: A0A8C5KFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Pold1
gene id: 51337:Pold1
uniprot id: A0A8C5JT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

51337:Rarb
gene id: 51337:Rarb
uniprot id: A0A8C5K0Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Atf4
gene id: 51337:Atf4
uniprot id: A0A8C5KRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

51337:Dhh
gene id: 51337:Dhh
uniprot id: A0A8C5JWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

51337:Atpaf2
gene id: 51337:Atpaf2
uniprot id: A0A8C5KD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

51337:Htr7
gene id: 51337:Htr7
uniprot id: A0A8C5L0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Sppl3
gene id: 51337:Sppl3
uniprot id: A0A8C5LJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

51337:Higd1a
gene id: 51337:Higd1a
uniprot id: A0A8C5KI32
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

51337:Elk1
gene id: 51337:Elk1
uniprot id: A0A8C5KAY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Gpn2
gene id: 51337:Gpn2
uniprot id: A0A8C5LDJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

51337:Supt6h
gene id: 51337:Supt6h
uniprot id: A0A8C5KI55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

51337:Psme3ip1
gene id: 51337:Psme3ip1
uniprot id: A0A8C5K0J2
names: Subcellular Location Annotation
messages: Nucleus

51337:Scai
gene id: 51337:Scai
uniprot id: A0A8C5L910
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

51337:Iqsec2
gene id: 51337:Iqsec2
uniprot id: A0A8C5KFC7
names: Similarity
messages: Belongs to the BRAG family.

51337:Nutf2
gene id: 51337:Nutf2
uniprot id: A0A8C5P4D4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

51337:LOC101613387
gene id: 51337:LOC101613387
uniprot id: A0A8C5K900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

51337:LOC101608764
gene id: 51337:LOC101608764
uniprot id: A0A8C5KFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tox4
gene id: 51337:Tox4
uniprot id: A0A8C5JY51
names: Subcellular Location Annotation
messages: Nucleus

51337:Ntrk2
gene id: 51337:Ntrk2
uniprot id: A0A8C5LD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

51337:Lzts2
gene id: 51337:Lzts2
uniprot id: A0A8C5KPQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Interacts with KATNB1. Also interacts with CTNNB1, gamma-tubulin and KIF23.
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

51337:Grpel2
gene id: 51337:Grpel2
uniprot id: A0A8C5K224
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

51337:LOC101597709
gene id: 51337:LOC101597709
uniprot id: A0A8C5KSG8
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

51337:LOC101598825
gene id: 51337:LOC101598825
uniprot id: A0A8C5K058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Ccn3
gene id: 51337:Ccn3
uniprot id: A0A8C5LBT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Cep43
gene id: 51337:Cep43
uniprot id: A0A8C5LL13
uniprot id: A0A8C5LMW8
names: Subcellular Location Annotation
messages: centriole

51337:L3hypdh
gene id: 51337:L3hypdh
uniprot id: A0A8C5P587
names: Similarity
messages: Belongs to the proline racemase family.

51337:Srsf4
gene id: 51337:Srsf4
uniprot id: A0A8C5LAG8
names: Similarity
messages: Belongs to the splicing factor SR family.

51337:Rps17
gene id: 51337:Rps17
uniprot id: A0A8C5LA80
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

51337:Pdgfb
gene id: 51337:Pdgfb
uniprot id: A0A8C5KTK3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

51337:Apoa1
gene id: 51337:Apoa1
uniprot id: P0DMS3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein A1/A4/E family.
messages: Glycosylated.
messages: Homodimer (By similarity). Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin. Interacts with NDRG1. Interacts with SCGB3A2 (By similarity). Interacts with NAXE and YJEFN3 (By similarity).
messages: Palmitoylated.
messages: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
messages: Phosphorylation sites are present in the extracellular medium.
messages: Secreted

51337:Lpxn
gene id: 51337:Lpxn
uniprot id: A0A8C5LGC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Cell membrane
messages: Cytoplasm
messages: Nucleus
messages: The LIM domain 3 is critical for focal adhesion targeting and the suppression of paxillin (PXN) tyrosine phosphorylation. The LIM domain 3 alone or both LIM domains 3 and 4 can mediate interaction with AR.
messages: Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN).
messages: focal adhesion
messages: perinuclear region
messages: podosome

51337:LOC101596804
gene id: 51337:LOC101596804
uniprot id: A0A8C5LJD0
names: Similarity
messages: Belongs to the intermediate filament family.

51337:LOC101615231
gene id: 51337:LOC101615231
uniprot id: A0A8C5KIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Dmac2l
gene id: 51337:Dmac2l
uniprot id: A0A8C5KWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Ffar4
gene id: 51337:Ffar4
uniprot id: A0A8C5NWE0
names: Subcellular Location Annotation
messages: Membrane

51337:Map3k8
gene id: 51337:Map3k8
uniprot id: A0A8C5KAI0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

51337:Pla2g3
gene id: 51337:Pla2g3
uniprot id: A0A8C5L6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

51337:Gpr139
gene id: 51337:Gpr139
uniprot id: A0A8C5KMJ9
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101607659
gene id: 51337:LOC101607659
uniprot id: A0A8C5K5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

51337:LOC101612220
gene id: 51337:LOC101612220
uniprot id: A0A8C5KI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Grap2
gene id: 51337:Grap2
uniprot id: A0A8C5KLW5
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

51337:Inpp1
gene id: 51337:Inpp1
uniprot id: A0A8C5NWC6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

51337:P2rx1
gene id: 51337:P2rx1
uniprot id: A0A8C5KDF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

51337:Hexd
gene id: 51337:Hexd
uniprot id: A0A8C5KN98
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

51337:Ctsk
gene id: 51337:Ctsk
uniprot id: A0A8C5K9R2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Cell membrane
messages: Lysosome
messages: Secreted

51337:Grk5
gene id: 51337:Grk5
uniprot id: A0A8C5LA53
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

51337:Glp2r
gene id: 51337:Glp2r
uniprot id: A0A8C5NV98
names: Subcellular Location Annotation
messages: Membrane

51337:Ackr1
gene id: 51337:Ackr1
uniprot id: A0A8C5LH62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
messages: Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
messages: Early endosome
messages: Membrane
messages: Recycling endosome

51337:Ppp1r10
gene id: 51337:Ppp1r10
uniprot id: A0A8C5K653
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

51337:Bbs4
gene id: 51337:Bbs4
uniprot id: A0A8C5KWE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

51337:Mtmr2
gene id: 51337:Mtmr2
uniprot id: A0A8C5K5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

51337:Mpp1
gene id: 51337:Mpp1
uniprot id: A0A8C5NWM0
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

51337:Gnaz
gene id: 51337:Gnaz
uniprot id: A0A8C5KAI9
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

51337:Bap1
gene id: 51337:Bap1
uniprot id: A0A8C5LJ91
names: Similarity
messages: Belongs to the peptidase C12 family.

51337:Tmem234
gene id: 51337:Tmem234
uniprot id: A0A8C5K938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

51337:Hmmr
gene id: 51337:Hmmr
uniprot id: A0A8C5LFT1
names: Subcellular Location Annotation
messages: spindle

51337:LOC101602190
gene id: 51337:LOC101602190
uniprot id: A0A8C5KGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Rbm17
gene id: 51337:Rbm17
uniprot id: A0A8C5LC67
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

51337:Cxcr4
gene id: 51337:Cxcr4
uniprot id: A0A8C5K2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

51337:Atp5po
gene id: 51337:Atp5po
uniprot id: A0A8C5P4F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

51337:Celf2
gene id: 51337:Celf2
uniprot id: A0A8C5KD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

51337:Creb1
gene id: 51337:Creb1
uniprot id: A0A8C5KFT7
uniprot id: A0A8C5KHE0
names: Subcellular Location Annotation
messages: Nucleus

51337:Fmod
gene id: 51337:Fmod
uniprot id: A0A8C5KRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

51337:Ebf3
gene id: 51337:Ebf3
uniprot id: A0A8C5LFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

51337:Gsg1l
gene id: 51337:Gsg1l
uniprot id: A0A8C5P3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

51337:Pvalb
gene id: 51337:Pvalb
uniprot id: A0A8C5NVI6
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

51337:Scfd2
gene id: 51337:Scfd2
uniprot id: A0A8C5KIZ5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

51337:Foxl3
gene id: 51337:Foxl3
uniprot id: A0A8C5JYU9
names: Subcellular Location Annotation
messages: Nucleus

51337:Prdx2
gene id: 51337:Prdx2
uniprot id: A0A8C5P0V0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

51337:Tmem151a
gene id: 51337:Tmem151a
uniprot id: A0A8C5KG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

51337:KEG00 p10
gene id: 51337:KEG00_p10
uniprot id: Q710T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). Found in a complex with TMEM177, COA6, COX18, COX20, SCO1 and SCO2. Interacts with TMEM177 in a COX20-dependent manner. Interacts with COX20. Interacts with COX16.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

51337:LOC101595953
gene id: 51337:LOC101595953
uniprot id: A0A8C5LDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

51337:LOC101597969
gene id: 51337:LOC101597969
uniprot id: A0A8C5K907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

51337:LOC101614265
gene id: 51337:LOC101614265
uniprot id: A0A8C5JZD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Slc35c1
gene id: 51337:Slc35c1
uniprot id: A0A8C5P635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

51337:Trpc1
gene id: 51337:Trpc1
uniprot id: A0A8C5KVX3
uniprot id: A0A8C5P1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

51337:Serpinb12
gene id: 51337:Serpinb12
uniprot id: A0A8C5JXC0
names: Similarity
messages: Belongs to the serpin family.

51337:Tmem256
gene id: 51337:Tmem256
uniprot id: A0A8C5L823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

51337:Rbm10
gene id: 51337:Rbm10
uniprot id: A0A8C5KKX2
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101607907
gene id: 51337:LOC101607907
uniprot id: A0A8C5KIQ0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

51337:Camk2d
gene id: 51337:Camk2d
uniprot id: A0A8C5P0C8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

51337:LOC101612201
gene id: 51337:LOC101612201
uniprot id: A0A8C5K971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101609560
gene id: 51337:LOC101609560
uniprot id: A0A8C5P4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

51337:Ngrn
gene id: 51337:Ngrn
uniprot id: A0A8C5LFD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

51337:Ppp3cb
gene id: 51337:Ppp3cb
uniprot id: A0A8C5LA68
uniprot id: A0A8C5LE93
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

51337:Nupr1
gene id: 51337:Nupr1
uniprot id: A0A8C5K1R3
names: Similarity
messages: Belongs to the NUPR family.

51337:Kcng4
gene id: 51337:Kcng4
uniprot id: A0A8C5P0V3
names: Subcellular Location Annotation
messages: Membrane

51337:Tubb6
gene id: 51337:Tubb6
uniprot id: A0A8C5K521
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Smoc1
gene id: 51337:Smoc1
uniprot id: A0A8C5KTF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Ufl1
gene id: 51337:Ufl1
uniprot id: A0A8C5K3F8
names: Similarity
messages: Belongs to the UFL1 family.

51337:Coq9
gene id: 51337:Coq9
uniprot id: A0A8C5LHH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

51337:Nsun4
gene id: 51337:Nsun4
uniprot id: A0A8C5K1V3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

51337:Serpina5
gene id: 51337:Serpina5
uniprot id: A0A8C5L5L6
names: Similarity
messages: Belongs to the serpin family.

51337:Nr4a3
gene id: 51337:Nr4a3
uniprot id: A0A8C5JZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: Nucleus

51337:Tnfaip6
gene id: 51337:Tnfaip6
uniprot id: A0A8C5L4K1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Katna1
gene id: 51337:Katna1
uniprot id: A0A8C5LBM8
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

51337:Elavl2
gene id: 51337:Elavl2
uniprot id: A0A8C5K3G9
names: Similarity
messages: Belongs to the RRM elav family.

51337:Itga2b
gene id: 51337:Itga2b
uniprot id: A0A8C5L212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

51337:Sumf1
gene id: 51337:Sumf1
uniprot id: A0A8C5KL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

51337:Rap2a
gene id: 51337:Rap2a
uniprot id: A0A8C5L122
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

51337:Pde8b
gene id: 51337:Pde8b
uniprot id: A0A8C5P5P0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Lrrc8d
gene id: 51337:Lrrc8d
uniprot id: A0A8C5K0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

51337:LOC101613335
gene id: 51337:LOC101613335
uniprot id: A0A8C5K5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Kpna2
gene id: 51337:Kpna2
uniprot id: A0A8C5KVQ0
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

51337:Eef1d
gene id: 51337:Eef1d
uniprot id: A0A8C5KEV1
uniprot id: A0A8C5KIN2
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

51337:Acss2
gene id: 51337:Acss2
uniprot id: A0A8C5KHT5
uniprot id: A0A8C5KJG8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Ypel5
gene id: 51337:Ypel5
uniprot id: A0A8C5K704
names: Similarity
messages: Belongs to the yippee family.

51337:Dpysl5
gene id: 51337:Dpysl5
uniprot id: A0A8C5KQF2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

51337:Htr3b
gene id: 51337:Htr3b
uniprot id: A0A8C5K1X3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Tomm40
gene id: 51337:Tomm40
uniprot id: A0A8C5KQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:LOC101617718
gene id: 51337:LOC101617718
uniprot id: A0A8C5JWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

51337:Hoxa5
gene id: 51337:Hoxa5
uniprot id: A0A8C5KDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Camk2a
gene id: 51337:Camk2a
uniprot id: A0A8C5KE68
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

51337:LOC101603115
gene id: 51337:LOC101603115
uniprot id: A0A8C5K0Q4
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

51337:Ptbp1
gene id: 51337:Ptbp1
uniprot id: A0A8C5K7Q2
uniprot id: A0A8C5K868
names: Subcellular Location Annotation
messages: Nucleus

51337:Fbl
gene id: 51337:Fbl
uniprot id: A0A8C5P1Q9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

51337:Mpped2
gene id: 51337:Mpped2
uniprot id: A0A8C5JY73
names: Similarity
messages: Belongs to the UPF0046 family.

51337:Crybb3
gene id: 51337:Crybb3
uniprot id: A0A8C5L9I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

51337:Vbp1
gene id: 51337:Vbp1
uniprot id: A0A8C5KWA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

51337:Fgfr3
gene id: 51337:Fgfr3
uniprot id: A0A8C5JZN2
uniprot id: A0A8C5K1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

51337:Rps6ka4
gene id: 51337:Rps6ka4
uniprot id: A0A8C5NVN2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

51337:Gad2
gene id: 51337:Gad2
uniprot id: A0A8C5L1L9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

51337:Calhm1
gene id: 51337:Calhm1
uniprot id: A0A8C5K456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

51337:LOC105944721
gene id: 51337:LOC105944721
uniprot id: A0A8C5NTZ9
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

51337:Sh3pxd2a
gene id: 51337:Sh3pxd2a
uniprot id: A0A8C5KBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

51337:Htr2c
gene id: 51337:Htr2c
uniprot id: A0A8C5LEZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

51337:Rpl28
gene id: 51337:Rpl28
uniprot id: A0A8C5L4E5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

51337:Oxtr
gene id: 51337:Oxtr
uniprot id: A0A8C5KQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

51337:Pde6a
gene id: 51337:Pde6a
uniprot id: A0A8C5NUX3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Necap2
gene id: 51337:Necap2
uniprot id: A0A8C5L9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

51337:Cdh2
gene id: 51337:Cdh2
uniprot id: A0A8C5P1R2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Cell surface
messages: Membrane
messages: sarcolemma

51337:Fabp2
gene id: 51337:Fabp2
uniprot id: A0A8C5KT13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

51337:LOC101607945
gene id: 51337:LOC101607945
uniprot id: A0A8C5L7U0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Gpr34
gene id: 51337:Gpr34
uniprot id: A0A8C5KFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Bloc1s1
gene id: 51337:Bloc1s1
uniprot id: A0A8C5L7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space

51337:Kcnj3
gene id: 51337:Kcnj3
uniprot id: A0A8C5K0X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

51337:Kcns3
gene id: 51337:Kcns3
uniprot id: A0A8C5K242
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Bmt2
gene id: 51337:Bmt2
uniprot id: A0A8C5L146
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

51337:Slc2a6
gene id: 51337:Slc2a6
uniprot id: A0A8C5LDV2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

51337:Eny2
gene id: 51337:Eny2
uniprot id: A0A8C5KRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

51337:Ppfia2
gene id: 51337:Ppfia2
uniprot id: A0A8C5K3P6
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

51337:Cldn19
gene id: 51337:Cldn19
uniprot id: A0A8C5KPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Mrps7
gene id: 51337:Mrps7
uniprot id: A0A8C5KGQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

51337:Slc9a9
gene id: 51337:Slc9a9
uniprot id: A0A8C5L9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

51337:Hoxa9
gene id: 51337:Hoxa9
uniprot id: A0A8C5K0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

51337:Fabp4
gene id: 51337:Fabp4
uniprot id: A0A8C5P3D5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:Mfng
gene id: 51337:Mfng
uniprot id: A0A8C5K5T3
names: Subcellular Location Annotation
messages: Membrane

51337:Slc35e4
gene id: 51337:Slc35e4
uniprot id: A0A8C5KP78
names: Subcellular Location Annotation
messages: Membrane

51337:Nr0b1
gene id: 51337:Nr0b1
uniprot id: A0A8C5LB65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

51337:Tmsb15b
gene id: 51337:Tmsb15b
uniprot id: A0A8C5P144
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

51337:Mthfs
gene id: 51337:Mthfs
uniprot id: A0A8C5KFB8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

51337:Rnf114
gene id: 51337:Rnf114
uniprot id: A0A8C5L8Y9
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

51337:Spring1
gene id: 51337:Spring1
uniprot id: A0A8C5NV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Fam83d
gene id: 51337:Fam83d
uniprot id: A0A8C5L7A0
names: Similarity
messages: Belongs to the FAM83 family.

51337:Bmp4
gene id: 51337:Bmp4
uniprot id: A0A8C5K568
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Atxn7l3
gene id: 51337:Atxn7l3
uniprot id: A0A8C5KNJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ENY2 and USP22.
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of USP22 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

51337:LOC101604809
gene id: 51337:LOC101604809
uniprot id: A0A8C5NY21
names: Similarity
messages: Belongs to the SKP1 family.

51337:Tmem255b
gene id: 51337:Tmem255b
uniprot id: A0A8C5JZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

51337:Spc25
gene id: 51337:Spc25
uniprot id: A0A8C5L8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

51337:Atp5pb
gene id: 51337:Atp5pb
uniprot id: A0A8C5L522
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

51337:Fabp5
gene id: 51337:Fabp5
uniprot id: A0A8C5KCQ5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:Rbbp7
gene id: 51337:Rbbp7
uniprot id: A0A8C5KQM5
names: Subcellular Location Annotation
messages: Nucleus

51337:Aasdhppt
gene id: 51337:Aasdhppt
uniprot id: A0A8C5JYW9
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

51337:Lbr
gene id: 51337:Lbr
uniprot id: A0A8C5K5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

51337:Hoxb13
gene id: 51337:Hoxb13
uniprot id: A0A8C5KBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

51337:Pxmp4
gene id: 51337:Pxmp4
uniprot id: A0A8C5KX94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

51337:B3gat1
gene id: 51337:B3gat1
uniprot id: A0A8C5JU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Psmc5
gene id: 51337:Psmc5
uniprot id: A0A8C5KNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

51337:Atp6v1g2
gene id: 51337:Atp6v1g2
uniprot id: A0A8C5JZT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Wfikkn1
gene id: 51337:Wfikkn1
uniprot id: A0A8C5LDG4
names: Similarity
messages: Belongs to the WFIKKN family.

51337:Avil
gene id: 51337:Avil
uniprot id: A0A8C5KWI8
names: Similarity
messages: Belongs to the villin/gelsolin family.

51337:Prok2
gene id: 51337:Prok2
uniprot id: A0A8C5LBK5
uniprot id: A0A8C5P450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

51337:Plg
gene id: 51337:Plg
uniprot id: A0A8C5LGD4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

51337:Cmc4
gene id: 51337:Cmc4
uniprot id: A0A8C5KX56
names: Similarity
messages: Belongs to the CMC4 family.

51337:Enkur
gene id: 51337:Enkur
uniprot id: A0A8C5KWJ8
names: Subcellular Location Annotation
messages: cilium axoneme

51337:Traf4
gene id: 51337:Traf4
uniprot id: A0A8C5L8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

51337:Cplx1
gene id: 51337:Cplx1
uniprot id: A0A8C5KY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

51337:Mcm3
gene id: 51337:Mcm3
uniprot id: A0A8C5KZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

51337:Rara
gene id: 51337:Rara
uniprot id: A0A8C5JWP2
uniprot id: A0A8C5NUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Crabp1
gene id: 51337:Crabp1
uniprot id: A0A8C5NVK9
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

51337:Ap1g1
gene id: 51337:Ap1g1
uniprot id: A0A8C5LIU5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

51337:Smc6
gene id: 51337:Smc6
uniprot id: A0A8C5K7I0
names: Subcellular Location Annotation
messages: Chromosome

51337:Mios
gene id: 51337:Mios
uniprot id: A0A8C5L9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

51337:Slc35e3
gene id: 51337:Slc35e3
uniprot id: A0A8C5KWH3
names: Subcellular Location Annotation
messages: Membrane

51337:Cxcl13
gene id: 51337:Cxcl13
uniprot id: A0A8C5NZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

51337:Snrpd1
gene id: 51337:Snrpd1
uniprot id: A0A8C5KY79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
messages: cytosol

51337:Neurl2
gene id: 51337:Neurl2
uniprot id: A0A8C5K898
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Krt12
gene id: 51337:Krt12
uniprot id: A0A8C5LCZ2
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Insl3
gene id: 51337:Insl3
uniprot id: A0A8C5KQR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

51337:Exosc1
gene id: 51337:Exosc1
uniprot id: A0A8C5KJ27
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Fgg
gene id: 51337:Fgg
uniprot id: A0A8C5LDR5
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

51337:Rhbdd1
gene id: 51337:Rhbdd1
uniprot id: A0A8C5K0V9
names: Subcellular Location Annotation
messages: Membrane

51337:Serp1
gene id: 51337:Serp1
uniprot id: A0A8C5P136
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

51337:Mif
gene id: 51337:Mif
uniprot id: A0A8C5JUA7
names: Similarity
messages: Belongs to the MIF family.

51337:Cers6
gene id: 51337:Cers6
uniprot id: A0A8C5L5X9
uniprot id: A0A8C5L7T4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

51337:Tmem182
gene id: 51337:Tmem182
uniprot id: A0A8C5KD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

51337:Ncdn
gene id: 51337:Ncdn
uniprot id: A0A8C5KHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

51337:Luc7l3
gene id: 51337:Luc7l3
uniprot id: A0A8C5KB21
names: Similarity
messages: Belongs to the Luc7 family.

51337:Slc51a
gene id: 51337:Slc51a
uniprot id: A0A8C5JW78
names: Subcellular Location Annotation
messages: Membrane

51337:Hibadh
gene id: 51337:Hibadh
uniprot id: A0A8C5K5C6
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

51337:LOC101608091
gene id: 51337:LOC101608091
uniprot id: A0A8C5L267
names: Similarity
messages: Belongs to the CLCR family.

51337:Syne4
gene id: 51337:Syne4
uniprot id: A0A8C5K6C8
uniprot id: A0A8C5K6Z9
names: Similarity
messages: Belongs to the nesprin family.

51337:LOC101594274
gene id: 51337:LOC101594274
uniprot id: A0A8C5NU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

51337:Avpi1
gene id: 51337:Avpi1
uniprot id: A0A8C5P4E5
names: Function
messages: May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

51337:Galns
gene id: 51337:Galns
uniprot id: A0A8C5KEX6
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Homodimer.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Pim3
gene id: 51337:Pim3
uniprot id: A0A8C5LEZ5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

51337:Kcnmb4
gene id: 51337:Kcnmb4
uniprot id: A0A8C5JYL7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

51337:Pnck
gene id: 51337:Pnck
uniprot id: A0A8C5L841
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Gng3
gene id: 51337:Gng3
uniprot id: A0A8C5KR04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:Taf11
gene id: 51337:Taf11
uniprot id: A0A8C5LBK3
names: Similarity
messages: Belongs to the TAF11 family.

51337:Gys2
gene id: 51337:Gys2
uniprot id: A0A8C5L6V2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

51337:Tagln3
gene id: 51337:Tagln3
uniprot id: A0A8C5K901
names: Similarity
messages: Belongs to the calponin family.

51337:Brs3
gene id: 51337:Brs3
uniprot id: A0A8C5L2G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

51337:Atp6v1d
gene id: 51337:Atp6v1d
uniprot id: A0A8C5LMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: cilium
messages: clathrin-coated vesicle membrane

51337:Cep76
gene id: 51337:Cep76
uniprot id: A0A8C5LAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

51337:LOC101600843
gene id: 51337:LOC101600843
uniprot id: A0A8C5LCU9
names: Similarity
messages: Belongs to the aldo/keto reductase family.

51337:Tecrl
gene id: 51337:Tecrl
uniprot id: A0A8C5KVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

51337:LOC101610766
gene id: 51337:LOC101610766
uniprot id: A0A8C5KFZ0
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

51337:Ovol1
gene id: 51337:Ovol1
uniprot id: A0A8C5LMM4
names: Subcellular Location Annotation
messages: Nucleus

51337:Sbf1
gene id: 51337:Sbf1
uniprot id: A0A8C5JZL3
uniprot id: A0A8C5NVD2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

51337:Alox12
gene id: 51337:Alox12
uniprot id: A0A8C5JW80
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Bud31
gene id: 51337:Bud31
uniprot id: A0A8C5K1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

51337:Rad51
gene id: 51337:Rad51
uniprot id: A0A8C5L510
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

51337:Rfx2
gene id: 51337:Rfx2
uniprot id: A0A8C5K6E0
uniprot id: A0A8C5NW05
names: Subcellular Location Annotation
messages: Nucleus

51337:Supt5h
gene id: 51337:Supt5h
uniprot id: A0A8C5P4F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

51337:Mc5r
gene id: 51337:Mc5r
uniprot id: A0A8C5NXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

51337:Hcfc1
gene id: 51337:Hcfc1
uniprot id: A0A8C5KG72
names: Subcellular Location Annotation
messages: Nucleus

51337:Anapc15
gene id: 51337:Anapc15
uniprot id: A0A8C5L4J6
names: Similarity
messages: Belongs to the APC15 family.

51337:Mtcp1
gene id: 51337:Mtcp1
uniprot id: A0A8C5L3R8
names: Similarity
messages: Belongs to the TCL1 family.

51337:Epor
gene id: 51337:Epor
uniprot id: A0A8C5NVK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Forms homodimers on EPO stimulation.
messages: Membrane
messages: Receptor for erythropoietin.

51337:Cdc73
gene id: 51337:Cdc73
uniprot id: A0A8C5KX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

51337:Lpcat4
gene id: 51337:Lpcat4
uniprot id: A0A8C5P2C7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

51337:Neurod4
gene id: 51337:Neurod4
uniprot id: A0A8C5K290
names: Subcellular Location Annotation
messages: Nucleus

51337:Tmcc2
gene id: 51337:Tmcc2
uniprot id: A0A8C5LIV3
names: Similarity
messages: Belongs to the TEX28 family.

51337:Slc16a1
gene id: 51337:Slc16a1
uniprot id: A0A8C5LMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

51337:Gna14
gene id: 51337:Gna14
uniprot id: A0A8C5LD17
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

51337:Alg3
gene id: 51337:Alg3
uniprot id: A0A8C5NU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the glycosyltransferase 58 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Nab2
gene id: 51337:Nab2
uniprot id: A0A8C5KPC0
uniprot id: A0A8C5P0E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

51337:Jund
gene id: 51337:Jund
uniprot id: A0A8C5K2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

51337:Abhd16a
gene id: 51337:Abhd16a
uniprot id: A0A8C5KD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

51337:Rpp14
gene id: 51337:Rpp14
uniprot id: A0A8C5KY97
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

51337:Alkal1
gene id: 51337:Alkal1
uniprot id: A0A8C5JVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

51337:Hapln3
gene id: 51337:Hapln3
uniprot id: A0A8C5K1I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Slu7
gene id: 51337:Slu7
uniprot id: A0A8C5NX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

51337:Rpl34
gene id: 51337:Rpl34
uniprot id: A0A8C5KTK1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

51337:Ppp1r21
gene id: 51337:Ppp1r21
uniprot id: A0A8C5L6H0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

51337:Tnc
gene id: 51337:Tnc
uniprot id: A0A8C5KHE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

51337:Ypel1
gene id: 51337:Ypel1
uniprot id: A0A8C5LGW2
names: Similarity
messages: Belongs to the yippee family.

51337:Sar1b
gene id: 51337:Sar1b
uniprot id: A0A8C5JWW3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

51337:Ctbs
gene id: 51337:Ctbs
uniprot id: A0A8C5KZW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

51337:Get1
gene id: 51337:Get1
uniprot id: A0A8C5KMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:A4gnt
gene id: 51337:A4gnt
uniprot id: A0A8C5P4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

51337:Cnot11
gene id: 51337:Cnot11
uniprot id: A0A8C5KVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

51337:Dusp10
gene id: 51337:Dusp10
uniprot id: A0A8C5LD24
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

51337:Slc27a2
gene id: 51337:Slc27a2
uniprot id: A0A8C5KCU6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Arf4
gene id: 51337:Arf4
uniprot id: A0A8C5KFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

51337:Otc
gene id: 51337:Otc
uniprot id: A0A8C5KWX8
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

51337:Wasl
gene id: 51337:Wasl
uniprot id: A0A8C5KAJ7
names: Subcellular Location Annotation
messages: Nucleus

51337:Psmd6
gene id: 51337:Psmd6
uniprot id: A0A8C5P3E4
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

51337:Bdkrb2
gene id: 51337:Bdkrb2
uniprot id: A0A8C5L501
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

51337:Lgr5
gene id: 51337:Lgr5
uniprot id: A0A8C5LD11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:LOC101598588
gene id: 51337:LOC101598588
uniprot id: A0A8C5JWZ9
names: Similarity
messages: Belongs to the yippee family.

51337:Zeb2
gene id: 51337:Zeb2
uniprot id: A0A8C5KQ43
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

51337:Cnpy2
gene id: 51337:Cnpy2
uniprot id: A0A8C5L7T7
names: Similarity
messages: Belongs to the canopy family.

51337:LOC101617980
gene id: 51337:LOC101617980
uniprot id: A0A8C5KMA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Gemin2
gene id: 51337:Gemin2
uniprot id: A0A8C5LDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

51337:Orai1
gene id: 51337:Orai1
uniprot id: A0A8C5NVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

51337:Fabp7
gene id: 51337:Fabp7
uniprot id: A0A8C5K547
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:LOC101602654
gene id: 51337:LOC101602654
uniprot id: A0A8C5KFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Slco3a1
gene id: 51337:Slco3a1
uniprot id: A0A8C5KMW7
uniprot id: A0A8C5KNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

51337:Leo1
gene id: 51337:Leo1
uniprot id: A0A8C5KYE6
names: Similarity
messages: Belongs to the LEO1 family.

51337:Slc10a1
gene id: 51337:Slc10a1
uniprot id: A0A8C5K700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

51337:Smad3
gene id: 51337:Smad3
uniprot id: A0A8C5L7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

51337:KEG00 p02
gene id: 51337:KEG00_p02
uniprot id: Q710S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

51337:Lctl
gene id: 51337:Lctl
uniprot id: A0A8C5KJX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

51337:LOC101617962
gene id: 51337:LOC101617962
uniprot id: A0A8C5KG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Loxhd1
gene id: 51337:Loxhd1
uniprot id: A0A8C5KBI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101603175
gene id: 51337:LOC101603175
uniprot id: A0A8C5KAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

51337:Ndufb6
gene id: 51337:Ndufb6
uniprot id: A0A8C5LEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Arg1
gene id: 51337:Arg1
uniprot id: A0A8C5KS24
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

51337:Spopl
gene id: 51337:Spopl
uniprot id: A0A8C5K8W0
names: Similarity
messages: Belongs to the Tdpoz family.

51337:Hoxa11
gene id: 51337:Hoxa11
uniprot id: A0A8C5L170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

51337:LOC101604549
gene id: 51337:LOC101604549
uniprot id: A0A8C5JW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

51337:Wls
gene id: 51337:Wls
uniprot id: A0A8C5NX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Slc33a1
gene id: 51337:Slc33a1
uniprot id: A0A8C5JYN3
names: Subcellular Location Annotation
messages: Membrane

51337:Prkcg
gene id: 51337:Prkcg
uniprot id: A0A8C5NW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

51337:Kcnv1
gene id: 51337:Kcnv1
uniprot id: A0A8C5KX39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

51337:Cldn3
gene id: 51337:Cldn3
uniprot id: A0A8C5JXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Ube2d3
gene id: 51337:Ube2d3
uniprot id: A0A8C5JXB0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Fgf3
gene id: 51337:Fgf3
uniprot id: A0A8C5L8H3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Psma8
gene id: 51337:Psma8
uniprot id: A0A8C5LFB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

51337:Cpt1c
gene id: 51337:Cpt1c
uniprot id: A0A8C5K5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:LOC101601962
gene id: 51337:LOC101601962
uniprot id: A0A8C5JYP9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

51337:Alox5
gene id: 51337:Alox5
uniprot id: A0A8C5L8X5
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Mrpl21
gene id: 51337:Mrpl21
uniprot id: A0A8C5KXW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL21 family.

51337:LOC101604980
gene id: 51337:LOC101604980
uniprot id: A0A8C5KMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:LOC101594019
gene id: 51337:LOC101594019
uniprot id: A0A8C5KNA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Matn4
gene id: 51337:Matn4
uniprot id: A0A8C5KF23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Cadm1
gene id: 51337:Cadm1
uniprot id: A0A8C5L069
uniprot id: A0A8C5L0B7
uniprot id: A0A8C5L0U8
uniprot id: A0A8C5P1M8
uniprot id: A0A8C5P218
names: Similarity
messages: Belongs to the nectin family.

51337:Kcnmb2
gene id: 51337:Kcnmb2
uniprot id: A0A8C5P443
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

51337:Cpne8
gene id: 51337:Cpne8
uniprot id: A0A8C5KNY7
names: Similarity
messages: Belongs to the copine family.

51337:LOC101613930
gene id: 51337:LOC101613930
uniprot id: A0A8C5LHZ6
names: Similarity
messages: Belongs to the aldo/keto reductase family.

51337:LOC101610812
gene id: 51337:LOC101610812
uniprot id: A0A8C5LBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

51337:Slc22a8
gene id: 51337:Slc22a8
uniprot id: A0A8C5LBR8
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

51337:Atp6v1c1
gene id: 51337:Atp6v1c1
uniprot id: A0A8C5KWC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

51337:Itm2a
gene id: 51337:Itm2a
uniprot id: A0A8C5KV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

51337:Miga2
gene id: 51337:Miga2
uniprot id: A0A8C5K191
names: Similarity
messages: Belongs to the mitoguardin family.

51337:Cnih2
gene id: 51337:Cnih2
uniprot id: A0A8C5NWJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

51337:Nudcd1
gene id: 51337:Nudcd1
uniprot id: A0A8C5KZG2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Ermn
gene id: 51337:Ermn
uniprot id: A0A8C5KWK7
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

51337:LOC101610497
gene id: 51337:LOC101610497
uniprot id: A0A8C5NYB7
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

51337:Actr2
gene id: 51337:Actr2
uniprot id: A0A8C5K5R8
names: Similarity
messages: Belongs to the actin family.

51337:Fam76a
gene id: 51337:Fam76a
uniprot id: A0A8C5JXE6
uniprot id: A0A8C5JYA2
names: Similarity
messages: Belongs to the FAM76 family.

51337:Kdm4a
gene id: 51337:Kdm4a
uniprot id: A0A8C5NX19
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

51337:Dcn
gene id: 51337:Dcn
uniprot id: A0A8C5L0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

51337:Pgs1
gene id: 51337:Pgs1
uniprot id: A0A8C5NZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

51337:Rpl26
gene id: 51337:Rpl26
uniprot id: A0A8C5K957
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

51337:Atp5f1d
gene id: 51337:Atp5f1d
uniprot id: A0A8C5NUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Mitochondrion inner membrane

51337:Higd1b
gene id: 51337:Higd1b
uniprot id: A0A8C5KVK8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

51337:Arl8a
gene id: 51337:Arl8a
uniprot id: A0A8C5LFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Synapse
messages: axon
messages: spindle

51337:Thoc5
gene id: 51337:Thoc5
uniprot id: A0A8C5NWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

51337:Hdac1
gene id: 51337:Hdac1
uniprot id: A0A8C5LC80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

51337:Caly
gene id: 51337:Caly
uniprot id: A0A8C5LFJ5
names: Similarity
messages: Belongs to the NSG family.

51337:Kcnj8
gene id: 51337:Kcnj8
uniprot id: A0A8C5L7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

51337:Ppm1l
gene id: 51337:Ppm1l
uniprot id: A0A8C5L6E1
names: Similarity
messages: Belongs to the PP2C family.

51337:LOC101612135
gene id: 51337:LOC101612135
uniprot id: A0A8C5KDR2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

51337:Fgf9
gene id: 51337:Fgf9
uniprot id: A0A8C5KD73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
messages: Secreted

51337:Rsad1
gene id: 51337:Rsad1
uniprot id: A0A8C5K9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

51337:Tbcb
gene id: 51337:Tbcb
uniprot id: A0A8C5LML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCB family.
messages: Cytoplasm

51337:Odf1
gene id: 51337:Odf1
uniprot id: A0A8C5NVG8
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

51337:Fgf10
gene id: 51337:Fgf10
uniprot id: A0A8C5K2E1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:Acsl4
gene id: 51337:Acsl4
uniprot id: A0A8C5L755
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Rad23b
gene id: 51337:Rad23b
uniprot id: A0A8C5L1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

51337:Kcns1
gene id: 51337:Kcns1
uniprot id: A0A8C5KRY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Emc2
gene id: 51337:Emc2
uniprot id: A0A8C5L8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

51337:Polr2e
gene id: 51337:Polr2e
uniprot id: A0A8C5P0X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

51337:Six6
gene id: 51337:Six6
uniprot id: A0A8C5JYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

51337:Trmt6
gene id: 51337:Trmt6
uniprot id: A0A8C5K3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

51337:Fyttd1
gene id: 51337:Fyttd1
uniprot id: A0A8C5KQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle

51337:Rab29
gene id: 51337:Rab29
uniprot id: A0A8C5LCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

51337:Celf1
gene id: 51337:Celf1
uniprot id: A0A8C5L632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

51337:Hes7
gene id: 51337:Hes7
uniprot id: A0A8C5K7B1
names: Subunit
messages: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.

51337:Lin7b
gene id: 51337:Lin7b
uniprot id: A0A8C5K2A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

51337:LOC101599655
gene id: 51337:LOC101599655
uniprot id: A0A8C5K5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

51337:Ckap5
gene id: 51337:Ckap5
uniprot id: A0A8C5LKB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

51337:Nos3
gene id: 51337:Nos3
uniprot id: A0A8C5K1T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

51337:Timm8b
gene id: 51337:Timm8b
uniprot id: A0A8C5KSK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

51337:Tmem17
gene id: 51337:Tmem17
uniprot id: A0A8C5K3I0
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101600081
gene id: 51337:LOC101600081
uniprot id: A0A8C5L156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

51337:Actrt3
gene id: 51337:Actrt3
uniprot id: A0A8C5P658
names: Similarity
messages: Belongs to the actin family.

51337:Slc6a17
gene id: 51337:Slc6a17
uniprot id: A0A8C5JUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:Tyr
gene id: 51337:Tyr
uniprot id: A0A8C5K395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

51337:Nkx2-8
gene id: 51337:Nkx2-8
uniprot id: A0A8C5L790
names: Subcellular Location Annotation
messages: Nucleus

51337:Ccnd2
gene id: 51337:Ccnd2
uniprot id: A0A8C5KFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

51337:Dgcr6l
gene id: 51337:Dgcr6l
uniprot id: A0A8C5KIV5
names: Similarity
messages: Belongs to the gonadal family.

51337:Cldn15
gene id: 51337:Cldn15
uniprot id: A0A8C5LGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Cuedc2
gene id: 51337:Cuedc2
uniprot id: A0A8C5L2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

51337:Tmem183a
gene id: 51337:Tmem183a
uniprot id: A0A8C5K9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

51337:Fads6
gene id: 51337:Fads6
uniprot id: A0A8C5K975
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

51337:Galnt3
gene id: 51337:Galnt3
uniprot id: A0A8C5KQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Nudt12
gene id: 51337:Nudt12
uniprot id: A0A8C5K8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

51337:Alas1
gene id: 51337:Alas1
uniprot id: A0A8C5JWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

51337:Prkra
gene id: 51337:Prkra
uniprot id: A0A8C5KEH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

51337:Nr2e1
gene id: 51337:Nr2e1
uniprot id: A0A8C5LBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Asah2
gene id: 51337:Asah2
uniprot id: A0A8C5K3B3
names: Similarity
messages: Belongs to the neutral ceramidase family.

51337:Creld2
gene id: 51337:Creld2
uniprot id: A0A8C5K9G3
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Pdcl
gene id: 51337:Pdcl
uniprot id: A0A8C5NWZ7
names: Similarity
messages: Belongs to the phosducin family.

51337:Rbm15
gene id: 51337:Rbm15
uniprot id: A0A8C5LDQ8
names: Similarity
messages: Belongs to the RRM Spen family.

51337:Smarcd1
gene id: 51337:Smarcd1
uniprot id: A0A8C5KQ42
names: Similarity
messages: Belongs to the SMARCD family.

51337:Hpd
gene id: 51337:Hpd
uniprot id: A0A8C5NYB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

51337:Fli1
gene id: 51337:Fli1
uniprot id: A0A8C5NYW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Nrxn1
gene id: 51337:Nrxn1
uniprot id: A0A8C5KB37
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Trex2
gene id: 51337:Trex2
uniprot id: A0A8C5KHU8
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

51337:Lamb2
gene id: 51337:Lamb2
uniprot id: A0A8C5KGS2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

51337:Apoc4
gene id: 51337:Apoc4
uniprot id: A0A8C5KVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C4 family.
messages: May participate in lipoprotein metabolism.
messages: Secreted

51337:Eif2b1
gene id: 51337:Eif2b1
uniprot id: A0A8C5KL35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

51337:Tnfsf14
gene id: 51337:Tnfsf14
uniprot id: A0A8C5NV26
names: Similarity
messages: Belongs to the tumor necrosis factor family.

51337:Actl7b
gene id: 51337:Actl7b
uniprot id: A0A8C5NVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

51337:Tubgcp4
gene id: 51337:Tubgcp4
uniprot id: A0A8C5KD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

51337:Gtf2h5
gene id: 51337:Gtf2h5
uniprot id: A0A8C5KPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

51337:Pamr1
gene id: 51337:Pamr1
uniprot id: A0A8C5NV03
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101596637
gene id: 51337:LOC101596637
uniprot id: A0A8C5KGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

51337:Vax2
gene id: 51337:Vax2
uniprot id: A0A8C5LFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

51337:Tbl1x
gene id: 51337:Tbl1x
uniprot id: A0A8C5K0Z9
names: Similarity
messages: Belongs to the WD repeat EBI family.

51337:Sema4g
gene id: 51337:Sema4g
uniprot id: A0A8C5JUH0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Star
gene id: 51337:Star
uniprot id: A0A8C5KKT1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

51337:Sult2b1
gene id: 51337:Sult2b1
uniprot id: A0A8C5LC69
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:Fat1
gene id: 51337:Fat1
uniprot id: A0A8C5KAK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Usp16
gene id: 51337:Usp16
uniprot id: A0A8C5L5F7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homotetramer.
messages: Nucleus
messages: Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

51337:LOC105944150
gene id: 51337:LOC105944150
uniprot id: A0A8C5K449
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

51337:Fen1
gene id: 51337:Fen1
uniprot id: A0A8C5KGY3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by EP300. Acetylation inhibits both endonuclease and exonuclease activity. Acetylation also reduces DNA-binding activity but does not affect interaction with PCNA or EP300.
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of Fen1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity. The C-terminal domain binds EP300. Can bind simultaneously to both PCNA and EP300. Interacts with DDX11.
messages: Methylation at Arg-192 by PRMT5 impedes Ser-187 phosphorylation and increases interaction with PCNA.
messages: Mitochondrion
messages: Phosphorylation upon DNA damage induces relocalization to the nuclear plasma. Phosphorylation at Ser-187 by CDK2 occurs during late S-phase and results in dissociation from PCNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

51337:Kcnh4
gene id: 51337:Kcnh4
uniprot id: A0A8C5LA19
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

51337:S1pr3
gene id: 51337:S1pr3
uniprot id: A0A8C5KED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:B9d2
gene id: 51337:B9d2
uniprot id: A0A8C5KIH1
names: Subcellular Location Annotation
messages: cilium basal body

51337:G6pc1
gene id: 51337:G6pc1
uniprot id: A0A8C5L4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

51337:Ficd
gene id: 51337:Ficd
uniprot id: A0A8C5L8D0
names: Similarity
messages: Belongs to the fic family.

51337:Pcolce
gene id: 51337:Pcolce
uniprot id: A0A8C5L5P6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Nfrkb
gene id: 51337:Nfrkb
uniprot id: A0A8C5L5A3
names: Subcellular Location Annotation
messages: Nucleus

51337:Isca1
gene id: 51337:Isca1
uniprot id: A0A8C5LAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

51337:Camk1d
gene id: 51337:Camk1d
uniprot id: A0A8C5KA36
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Syngr3
gene id: 51337:Syngr3
uniprot id: A0A8C5LFM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

51337:LOC101595809
gene id: 51337:LOC101595809
uniprot id: A0A8C5NXD4
names: Similarity
messages: Belongs to the PROTOR family.

51337:LOC101601620
gene id: 51337:LOC101601620
uniprot id: A0A8C5L4U6
names: Subcellular Location Annotation
messages: Membrane

51337:Mpp2
gene id: 51337:Mpp2
uniprot id: A0A8C5KYB9
uniprot id: A0A8C5P0X1
names: Similarity
messages: Belongs to the MAGUK family.

51337:LOC101594764
gene id: 51337:LOC101594764
uniprot id: A0A8C5KKN1
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Hspa1l
gene id: 51337:Hspa1l
uniprot id: A0A8C5L221
names: Similarity
messages: Belongs to the heat shock protein 70 family.

51337:Atp6v0d2
gene id: 51337:Atp6v0d2
uniprot id: A0A8C5KNC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Wnt10a
gene id: 51337:Wnt10a
uniprot id: A0A8C5P287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Sypl1
gene id: 51337:Sypl1
uniprot id: A0A8C5JVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

51337:Suds3
gene id: 51337:Suds3
uniprot id: A0A8C5JXD1
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101603958
gene id: 51337:LOC101603958
uniprot id: A0A8C5KBV2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

51337:Slc2a4
gene id: 51337:Slc2a4
uniprot id: A0A8C5NYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Membrane
messages: perinuclear region

51337:Megf6
gene id: 51337:Megf6
uniprot id: A0A8C5LCJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Slc7a11
gene id: 51337:Slc7a11
uniprot id: A0A8C5KDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

51337:Ano8
gene id: 51337:Ano8
uniprot id: A0A8C5KDB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Cacnb1
gene id: 51337:Cacnb1
uniprot id: A0A8C5K555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

51337:Surf6
gene id: 51337:Surf6
uniprot id: A0A8C5P0P8
names: Similarity
messages: Belongs to the SURF6 family.

51337:Vsnl1
gene id: 51337:Vsnl1
uniprot id: A0A8C5KE51
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

51337:Ntf4
gene id: 51337:Ntf4
uniprot id: A0A8C5KCU0
names: Similarity
messages: Belongs to the NGF-beta family.

51337:Rhbdd2
gene id: 51337:Rhbdd2
uniprot id: A0A8C5P061
names: Subcellular Location Annotation
messages: Membrane

51337:Serpinb11
gene id: 51337:Serpinb11
uniprot id: A0A8C5NUE3
names: Similarity
messages: Belongs to the serpin family.

51337:Inhbb
gene id: 51337:Inhbb
uniprot id: A0A8C5KJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

51337:Mmp19
gene id: 51337:Mmp19
uniprot id: A0A8C5L2Q5
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:Dok5
gene id: 51337:Dok5
uniprot id: A0A8C5L5G4
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

51337:Grpr
gene id: 51337:Grpr
uniprot id: A0A8C5L5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tubb1
gene id: 51337:Tubb1
uniprot id: A0A8C5L177
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Nop16
gene id: 51337:Nop16
uniprot id: A0A8C5P189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

51337:Abat
gene id: 51337:Abat
uniprot id: A0A8C5LHR4
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

51337:Gpr119
gene id: 51337:Gpr119
uniprot id: A0A8C5KQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:LOC101601450
gene id: 51337:LOC101601450
uniprot id: A0A8C5KBA5
names: Subcellular Location Annotation
messages: Membrane

51337:Sat1
gene id: 51337:Sat1
uniprot id: A0A8C5KYP4
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

51337:Mcm5
gene id: 51337:Mcm5
uniprot id: A0A8C5K084
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

51337:Fam136a
gene id: 51337:Fam136a
uniprot id: A0A8C5KR50
names: Similarity
messages: Belongs to the FAM136 family.

51337:LOC101614012
gene id: 51337:LOC101614012
uniprot id: A0A8C5NV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

51337:Sars1
gene id: 51337:Sars1
uniprot id: A0A8C5JVG7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

51337:Defb128
gene id: 51337:Defb128
uniprot id: A0A8C5KT47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

51337:LOC101614072
gene id: 51337:LOC101614072
uniprot id: A0A8C5KHQ4
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Sting1
gene id: 51337:Sting1
uniprot id: A0A8C5KHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

51337:Cacng4
gene id: 51337:Cacng4
uniprot id: A0A8C5L456
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

51337:Odf2
gene id: 51337:Odf2
uniprot id: A0A8C5L862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

51337:Cav2
gene id: 51337:Cav2
uniprot id: A0A8C5L9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

51337:Tfcp2l1
gene id: 51337:Tfcp2l1
uniprot id: A0A8C5KF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

51337:Popdc3
gene id: 51337:Popdc3
uniprot id: A0A8C5KK72
names: Similarity
messages: Belongs to the popeye family.

51337:Slitrk3
gene id: 51337:Slitrk3
uniprot id: A0A8C5KHY0
names: Similarity
messages: Belongs to the SLITRK family.

51337:Kcna2
gene id: 51337:Kcna2
uniprot id: A0A8C5K5S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

51337:Rps20
gene id: 51337:Rps20
uniprot id: A0A8C5K0D6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

51337:Pou1f1
gene id: 51337:Pou1f1
uniprot id: A0A8C5KAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-1 subfamily.
messages: Nucleus

51337:B3galt6
gene id: 51337:B3galt6
uniprot id: A0A8C5K436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Dlx1
gene id: 51337:Dlx1
uniprot id: A0A8C5K369
names: Subcellular Location Annotation
messages: Nucleus

51337:Glrb
gene id: 51337:Glrb
uniprot id: A0A8C5L3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:LOC101615892
gene id: 51337:LOC101615892
uniprot id: A0A8C5NXP3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

51337:Hdhd2
gene id: 51337:Hdhd2
uniprot id: A0A8C5LB21
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

51337:Vps37b
gene id: 51337:Vps37b
uniprot id: A0A8C5KQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

51337:Maob
gene id: 51337:Maob
uniprot id: A0A8C5KB15
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

51337:Tlx3
gene id: 51337:Tlx3
uniprot id: A0A8C5K948
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101612473
gene id: 51337:LOC101612473
uniprot id: A0A8C5K2F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

51337:Il6st
gene id: 51337:Il6st
uniprot id: A0A8C5KKI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

51337:LOC101617521
gene id: 51337:LOC101617521
uniprot id: A0A8C5K585
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

51337:C2H18orf32
gene id: 51337:C2H18orf32
uniprot id: A0A8C5KHQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: May activate the NF-kappa-B signaling pathway.

51337:Hapln1
gene id: 51337:Hapln1
uniprot id: A0A8C5KHI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Mymk
gene id: 51337:Mymk
uniprot id: A0A8C5NX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

51337:Azin1
gene id: 51337:Azin1
uniprot id: A0A8C5L8Y7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

51337:Sntb1
gene id: 51337:Sntb1
uniprot id: A0A8C5NV64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

51337:Bud23
gene id: 51337:Bud23
uniprot id: A0A8C5LEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

51337:Rnf20
gene id: 51337:Rnf20
uniprot id: A0A8C5P497
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

51337:Trappc5
gene id: 51337:Trappc5
uniprot id: A0A8C5KER6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

51337:Hnf4a
gene id: 51337:Hnf4a
uniprot id: A0A8C5L5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Nek8
gene id: 51337:Nek8
uniprot id: A0A8C5LG95
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

51337:Micos13
gene id: 51337:Micos13
uniprot id: A0A8C5LHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Erlin1
gene id: 51337:Erlin1
uniprot id: A0A8C5P0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

51337:Slc25a31
gene id: 51337:Slc25a31
uniprot id: A0A8C5LHA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

51337:Cert1
gene id: 51337:Cert1
uniprot id: A0A8C5LFU8
uniprot id: A0A8C5LK41
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

51337:Taar2
gene id: 51337:Taar2
uniprot id: A0A8C5LHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Pik3cb
gene id: 51337:Pik3cb
uniprot id: A0A8C5P598
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

51337:Tceanc2
gene id: 51337:Tceanc2
uniprot id: A0A8C5NVV5
names: Subcellular Location Annotation
messages: Nucleus

51337:Ube2g1
gene id: 51337:Ube2g1
uniprot id: A0A8C5KLI1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:LOC101599748
gene id: 51337:LOC101599748
uniprot id: A0A8C5KFR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

51337:Ctbp1
gene id: 51337:Ctbp1
uniprot id: A0A8C5LH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

51337:Bcar1
gene id: 51337:Bcar1
uniprot id: A0A8C5LMB9
uniprot id: A0A8C5P675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

51337:Eif2s1
gene id: 51337:Eif2s1
uniprot id: A0A8C5L296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

51337:Slc2a1
gene id: 51337:Slc2a1
uniprot id: A0A8C5KGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

51337:Vps18
gene id: 51337:Vps18
uniprot id: A0A8C5KKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

51337:Ctnnbip1
gene id: 51337:Ctnnbip1
uniprot id: A0A8C5KDH7
names: Similarity
messages: Belongs to the CTNNBIP1 family.

51337:Ccdc25
gene id: 51337:Ccdc25
uniprot id: A0A8C5KQ75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

51337:Il20
gene id: 51337:Il20
uniprot id: A0A8C5L5V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

51337:LOC101607106
gene id: 51337:LOC101607106
uniprot id: A0A8C5LE68
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

51337:Sufu
gene id: 51337:Sufu
uniprot id: A0A8C5K2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A).
messages: Nucleus

51337:Tuba8
gene id: 51337:Tuba8
uniprot id: A0A8C5LD84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

51337:Cep55
gene id: 51337:Cep55
uniprot id: A0A8C5K6M2
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Gc
gene id: 51337:Gc
uniprot id: A0A8C5LAR4
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

51337:Irf2bp1
gene id: 51337:Irf2bp1
uniprot id: A0A8C5K972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

51337:Fbxo46
gene id: 51337:Fbxo46
uniprot id: A0A8C5NX93
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

51337:Ptpn4
gene id: 51337:Ptpn4
uniprot id: A0A8C5JYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: May act at junctions between the membrane and the cytoskeleton.
messages: cytoskeleton

51337:Rad21l1
gene id: 51337:Rad21l1
uniprot id: A0A8C5KZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

51337:Atg4c
gene id: 51337:Atg4c
uniprot id: A0A8C5KSE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

51337:Slc23a1
gene id: 51337:Slc23a1
uniprot id: A0A8C5L2R4
names: Subcellular Location Annotation
messages: Membrane

51337:Bcl2
gene id: 51337:Bcl2
uniprot id: A0A8C5JYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

51337:Ccnt1
gene id: 51337:Ccnt1
uniprot id: A0A8C5KJT3
names: Similarity
messages: Belongs to the cyclin family. Cyclin C subfamily.

51337:Clcn7
gene id: 51337:Clcn7
uniprot id: A0A8C5LFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

51337:Isca2
gene id: 51337:Isca2
uniprot id: A0A8C5KRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

51337:Tmem201
gene id: 51337:Tmem201
uniprot id: A0A8C5KS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

51337:Rnpc3
gene id: 51337:Rnpc3
uniprot id: A0A8C5K4R6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Found in a complex with m(7)G-capped U12 snRNA. Interacts with PDCD7.
messages: Nucleus
messages: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

51337:Maco1
gene id: 51337:Maco1
uniprot id: A0A8C5K0P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

51337:Mmp11
gene id: 51337:Mmp11
uniprot id: A0A8C5NZK3
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:LOC101593524
gene id: 51337:LOC101593524
uniprot id: A0A8C5K0M3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Pygl
gene id: 51337:Pygl
uniprot id: A0A8C5KJC7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

51337:E2f3
gene id: 51337:E2f3
uniprot id: A0A8C5LGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

51337:Washc5
gene id: 51337:Washc5
uniprot id: A0A8C5L6P7
names: Similarity
messages: Belongs to the strumpellin family.

51337:Krt84
gene id: 51337:Krt84
uniprot id: A0A8C5KAM7
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Spon1
gene id: 51337:Spon1
uniprot id: A0A8C5L8M5
names: Subcellular Location Annotation
messages: extracellular matrix

51337:Nsg1
gene id: 51337:Nsg1
uniprot id: A0A8C5KYT9
names: Similarity
messages: Belongs to the NSG family.

51337:Coq7
gene id: 51337:Coq7
uniprot id: A0A8C5KVV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

51337:Phactr1
gene id: 51337:Phactr1
uniprot id: A0A8C5KYA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

51337:Uba1
gene id: 51337:Uba1
uniprot id: A0A8C5P2W3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

51337:Cntf
gene id: 51337:Cntf
uniprot id: A0A8C5LDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

51337:Moxd1
gene id: 51337:Moxd1
uniprot id: A0A8C5K1A7
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

51337:Wnt6
gene id: 51337:Wnt6
uniprot id: A0A8C5L746
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:LOC101610490
gene id: 51337:LOC101610490
uniprot id: A0A8C5KD40
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

51337:Plscr3
gene id: 51337:Plscr3
uniprot id: A0A8C5L767
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

51337:Garem1
gene id: 51337:Garem1
uniprot id: A0A8C5KF09
names: Similarity
messages: Belongs to the GAREM family.

51337:Napa
gene id: 51337:Napa
uniprot id: A0A8C5KG87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

51337:Adora1
gene id: 51337:Adora1
uniprot id: A0A8C5KHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

51337:Tph1
gene id: 51337:Tph1
uniprot id: A0A8C5LJ07
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

51337:Gabrb1
gene id: 51337:Gabrb1
uniprot id: A0A8C5LHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Atp4b
gene id: 51337:Atp4b
uniprot id: A0A8C5KZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

51337:Anp32b
gene id: 51337:Anp32b
uniprot id: A0A8C5P1S8
names: Similarity
messages: Belongs to the ANP32 family.

51337:Gstcd
gene id: 51337:Gstcd
uniprot id: A0A8C5LB64
names: Similarity
messages: Belongs to the GSTCD family.

51337:LOC101606646
gene id: 51337:LOC101606646
uniprot id: A0A8C5NZ19
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Cyfip1
gene id: 51337:Cyfip1
uniprot id: A0A8C5KZV5
uniprot id: A0A8C5P1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYFIP family.
messages: synaptosome

51337:Cpsf2
gene id: 51337:Cpsf2
uniprot id: A0A8C5KZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

51337:Hadhb
gene id: 51337:Hadhb
uniprot id: A0A8C5KUC5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

51337:LOC101593440
gene id: 51337:LOC101593440
uniprot id: A0A8C5L036
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Adam22
gene id: 51337:Adam22
uniprot id: A0A8C5K4Z9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Rps6ka2
gene id: 51337:Rps6ka2
uniprot id: A0A8C5K182
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

51337:Phf19
gene id: 51337:Phf19
uniprot id: A0A8C5KG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

51337:Tle1
gene id: 51337:Tle1
uniprot id: A0A8C5P1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

51337:Ap4m1
gene id: 51337:Ap4m1
uniprot id: A0A8C5K6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

51337:Gja4
gene id: 51337:Gja4
uniprot id: A0A8C5K5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Gdap1
gene id: 51337:Gdap1
uniprot id: A0A8C5KNQ9
names: Similarity
messages: Belongs to the GST superfamily.

51337:Mael
gene id: 51337:Mael
uniprot id: A0A8C5NXN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

51337:Gk
gene id: 51337:Gk
uniprot id: A0A8C5KPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

51337:LOC101616174
gene id: 51337:LOC101616174
uniprot id: A0A8C5JYY6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

51337:Fut9
gene id: 51337:Fut9
uniprot id: A0A8C5LDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

51337:Ddb1
gene id: 51337:Ddb1
uniprot id: A0A8C5P1B9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDB1 family.
messages: Component of complexes involved in DNA repair and protein ubiquitination. May play a role in the regulation of the circadian clock.
messages: Component of the UV-DDB complex.
messages: Nucleus
messages: The core of the protein consists of three WD40 beta-propeller domains.

51337:Vps35
gene id: 51337:Vps35
uniprot id: A0A8C5KLP9
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

51337:Hnmt
gene id: 51337:Hnmt
uniprot id: A0A8C5LB98
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

51337:Taldo1
gene id: 51337:Taldo1
uniprot id: A0A8C5P2Y8
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

51337:LOC101594353
gene id: 51337:LOC101594353
uniprot id: A0A8C5K150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-defensin family.
messages: Secreted

51337:Capn5
gene id: 51337:Capn5
uniprot id: A0A8C5LBH5
names: Similarity
messages: Belongs to the peptidase C2 family.

51337:Hmgn2
gene id: 51337:Hmgn2
uniprot id: A0A8C5L5G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

51337:Rem1
gene id: 51337:Rem1
uniprot id: A0A8C5L6F6
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

51337:Krtcap3
gene id: 51337:Krtcap3
uniprot id: A0A8C5KG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

51337:LOC101610412
gene id: 51337:LOC101610412
uniprot id: A0A8C5L3E0
names: Similarity
messages: Belongs to the NKAP family.

51337:Adprs
gene id: 51337:Adprs
uniprot id: A0A8C5JZT5
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

51337:Trim32
gene id: 51337:Trim32
uniprot id: A0A8C5NVL8
names: Similarity
messages: Belongs to the TRIM/RBCC family.

51337:LOC101613394
gene id: 51337:LOC101613394
uniprot id: A0A8C5KD56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Elmo3
gene id: 51337:Elmo3
uniprot id: A0A8C5KHF6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

51337:Atp4a
gene id: 51337:Atp4a
uniprot id: A0A8C5LL65
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

51337:KEG00 p12
gene id: 51337:KEG00_p12
uniprot id: Q710T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Hs6st2
gene id: 51337:Hs6st2
uniprot id: A0A8C5JXX8
uniprot id: A0A8C5JZI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

51337:LOC101608537
gene id: 51337:LOC101608537
uniprot id: A0A8C5NXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

51337:Cysltr1
gene id: 51337:Cysltr1
uniprot id: A0A8C5KNK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Panx2
gene id: 51337:Panx2
uniprot id: A0A8C5LG57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

51337:LOC101600832
gene id: 51337:LOC101600832
uniprot id: A0A8C5K5M1
names: Similarity
messages: Belongs to the peptidase A1 family.

51337:Pspn
gene id: 51337:Pspn
uniprot id: A0A8C5P5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

51337:Ddc
gene id: 51337:Ddc
uniprot id: A0A8C5LB23
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

51337:KEG00 p01
gene id: 51337:KEG00_p01
uniprot id: Q710S3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

51337:LOC101596855
gene id: 51337:LOC101596855
uniprot id: A0A8C5KPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

51337:LOC101599750
gene id: 51337:LOC101599750
uniprot id: A0A8C5K2V2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

51337:Polr3f
gene id: 51337:Polr3f
uniprot id: A0A8C5KXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

51337:Fam199x
gene id: 51337:Fam199x
uniprot id: A0A8C5L1Q5
names: Similarity
messages: Belongs to the FAM199 family.

51337:Aqp9
gene id: 51337:Aqp9
uniprot id: A0A8C5K131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

51337:LOC101608319
gene id: 51337:LOC101608319
uniprot id: A0A8C5K0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Lpcat2
gene id: 51337:Lpcat2
uniprot id: A0A8C5K1Q3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

51337:Pithd1
gene id: 51337:Pithd1
uniprot id: A0A8C5K444
names: Similarity
messages: Belongs to the PITHD1 family.

51337:Tubgcp6
gene id: 51337:Tubgcp6
uniprot id: A0A8C5NUV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

51337:Ap5m1
gene id: 51337:Ap5m1
uniprot id: A0A8C5KFD2
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

51337:Scgb1c1
gene id: 51337:Scgb1c1
uniprot id: A0A8C5K7L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

51337:Ormdl3
gene id: 51337:Ormdl3
uniprot id: A0A8C5LCI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

51337:Sncb
gene id: 51337:Sncb
uniprot id: A0A8C5KTR7
names: Similarity
messages: Belongs to the synuclein family.

51337:Foxs1
gene id: 51337:Foxs1
uniprot id: A0A8C5K3E8
names: Subcellular Location Annotation
messages: Nucleus

51337:S100a16
gene id: 51337:S100a16
uniprot id: A0A8C5KV87
names: Similarity
messages: Belongs to the S-100 family.

51337:Mnat1
gene id: 51337:Mnat1
uniprot id: A0A8C5K5A1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

51337:Mocs1
gene id: 51337:Mocs1
uniprot id: A0A8C5K3C5
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

51337:Hmox2
gene id: 51337:Hmox2
uniprot id: A0A8C5L002
names: Similarity
messages: Belongs to the heme oxygenase family.

51337:Fgf4
gene id: 51337:Fgf4
uniprot id: A0A8C5KBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

51337:Efhc1
gene id: 51337:Efhc1
uniprot id: A0A8C5L647
names: Subcellular Location Annotation
messages: cilium axoneme

51337:Spem1
gene id: 51337:Spem1
uniprot id: A0A8C5KTU5
names: Subcellular Location Annotation
messages: Membrane

51337:Rraga
gene id: 51337:Rraga
uniprot id: A0A8C5K2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

51337:Aadacl3
gene id: 51337:Aadacl3
uniprot id: A0A8C5KAZ2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

51337:Ipo5
gene id: 51337:Ipo5
uniprot id: A0A8C5K174
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Sptbn1
gene id: 51337:Sptbn1
uniprot id: A0A8C5KX90
names: Similarity
messages: Belongs to the spectrin family.

51337:Hdac2
gene id: 51337:Hdac2
uniprot id: A0A8C5JZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

51337:Pdrg1
gene id: 51337:Pdrg1
uniprot id: A0A8C5P396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

51337:Nacc2
gene id: 51337:Nacc2
uniprot id: A0A8C5K8V2
names: Subcellular Location Annotation
messages: Nucleus

51337:Raf1
gene id: 51337:Raf1
uniprot id: A0A8C5KR11
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

51337:Znf24
gene id: 51337:Znf24
uniprot id: A0A8C5KC34
names: Subcellular Location Annotation
messages: Nucleus

51337:Ndufb8
gene id: 51337:Ndufb8
uniprot id: A0A8C5L844
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Rpl13a
gene id: 51337:Rpl13a
uniprot id: A0A8C5JU22
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

51337:Ube2a
gene id: 51337:Ube2a
uniprot id: A0A8C5L3S3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Eif3k
gene id: 51337:Eif3k
uniprot id: A0A8C5KT31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

51337:Epha5
gene id: 51337:Epha5
uniprot id: A0A8C5LG88
uniprot id: A0A8C5P5J1
names: Subcellular Location Annotation
messages: Membrane

51337:Pmpca
gene id: 51337:Pmpca
uniprot id: A0A8C5KQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix
messages: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.

51337:LOC101617282
gene id: 51337:LOC101617282
uniprot id: A0A8C5L0X5
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

51337:Fgf13
gene id: 51337:Fgf13
uniprot id: A0A8C5P085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

51337:Cdc37
gene id: 51337:Cdc37
uniprot id: A0A8C5LBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

51337:Cdc37l1
gene id: 51337:Cdc37l1
uniprot id: A0A8C5LLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

51337:Slc35a5
gene id: 51337:Slc35a5
uniprot id: A0A8C5KHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

51337:Kcne2
gene id: 51337:Kcne2
uniprot id: A0A8C5KBN1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

51337:Rspo3
gene id: 51337:Rspo3
uniprot id: A0A8C5KGP4
names: Similarity
messages: Belongs to the R-spondin family.

51337:Zfp36
gene id: 51337:Zfp36
uniprot id: A0A8C5K6F3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

51337:LOC101597111
gene id: 51337:LOC101597111
uniprot id: A0A8C5P5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by in…
messages: Secreted

51337:Srms
gene id: 51337:Srms
uniprot id: A0A8C5L3G6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:Myod1
gene id: 51337:Myod1
uniprot id: A0A8C5LEV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

51337:Ina
gene id: 51337:Ina
uniprot id: A0A8C5LGG9
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Rps5
gene id: 51337:Rps5
uniprot id: A0A8C5K2L9
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

51337:Rps19bp1
gene id: 51337:Rps19bp1
uniprot id: A0A8C5KK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

51337:Irx4
gene id: 51337:Irx4
uniprot id: A0A8C5JTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

51337:LOC101603584
gene id: 51337:LOC101603584
uniprot id: A0A8C5KIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Smarcd3
gene id: 51337:Smarcd3
uniprot id: A0A8C5K5M8
names: Similarity
messages: Belongs to the SMARCD family.

51337:LOC101603596
gene id: 51337:LOC101603596
uniprot id: A0A8C5K4F2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Uchl3
gene id: 51337:Uchl3
uniprot id: A0A8C5KJF7
names: Similarity
messages: Belongs to the peptidase C12 family.

51337:Mgat5
gene id: 51337:Mgat5
uniprot id: A0A8C5KPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

51337:Polr2k
gene id: 51337:Polr2k
uniprot id: A0A8C5NTZ9
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

51337:Mmd
gene id: 51337:Mmd
uniprot id: A0A8C5KK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

51337:Yif1b
gene id: 51337:Yif1b
uniprot id: A0A8C5NYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

51337:Zdhhc24
gene id: 51337:Zdhhc24
uniprot id: A0A8C5K479
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Ptprb
gene id: 51337:Ptprb
uniprot id: A0A8C5KWZ1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

51337:Srf
gene id: 51337:Srf
uniprot id: A0A8C5L9Q5
names: Subcellular Location Annotation
messages: Nucleus

51337:Ccdc103
gene id: 51337:Ccdc103
uniprot id: A0A8C5P372
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

51337:Sardh
gene id: 51337:Sardh
uniprot id: A0A8C5KTB1
names: Similarity
messages: Belongs to the GcvT family.

51337:LOC101616129
gene id: 51337:LOC101616129
uniprot id: A0A8C5KQS0
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

51337:Krr1
gene id: 51337:Krr1
uniprot id: A0A8C5P5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

51337:Bmp8a
gene id: 51337:Bmp8a
uniprot id: A0A8C5KIT4
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Ehf
gene id: 51337:Ehf
uniprot id: A0A8C5LJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:LOC101612344
gene id: 51337:LOC101612344
uniprot id: A0A8C5L2N4
names: Similarity
messages: Belongs to the peptidase S14 family.

51337:Ruvbl2
gene id: 51337:Ruvbl2
uniprot id: A0A8C5NWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

51337:Nfic
gene id: 51337:Nfic
uniprot id: A0A8C5KP13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

51337:Slc7a5
gene id: 51337:Slc7a5
uniprot id: A0A8C5KLH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

51337:Tlcd3b
gene id: 51337:Tlcd3b
uniprot id: A0A8C5P3L8
names: Subcellular Location Annotation
messages: Membrane

51337:Lhx4
gene id: 51337:Lhx4
uniprot id: A0A8C5KAK3
names: Subcellular Location Annotation
messages: Nucleus

51337:Pemt
gene id: 51337:Pemt
uniprot id: A0A8C5P3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

51337:Ndufs8
gene id: 51337:Ndufs8
uniprot id: A0A8C5JZ23
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

51337:Dnal4
gene id: 51337:Dnal4
uniprot id: A0A8C5KM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

51337:Itga3
gene id: 51337:Itga3
uniprot id: A0A8C5K847
uniprot id: A0A8C5NX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

51337:Slc9a5
gene id: 51337:Slc9a5
uniprot id: A0A8C5K6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

51337:LOC101597073
gene id: 51337:LOC101597073
uniprot id: A0A8C5K7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

51337:Chmp7
gene id: 51337:Chmp7
uniprot id: A0A8C5KH78
names: Similarity
messages: Belongs to the SNF7 family.

51337:Eme1
gene id: 51337:Eme1
uniprot id: A0A8C5K7P8
names: Similarity
messages: Belongs to the EME1/MMS4 family.

51337:Eef1a1
gene id: 51337:Eef1a1
uniprot id: A0A8C5L8B6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

51337:Kcnd1
gene id: 51337:Kcnd1
uniprot id: A0A8C5K9R5
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

51337:Sec63
gene id: 51337:Sec63
uniprot id: A0A8C5KPV1
names: Subcellular Location Annotation
messages: Membrane

51337:Ube2n
gene id: 51337:Ube2n
uniprot id: A0A8C5KDS5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:LOC101598728
gene id: 51337:LOC101598728
uniprot id: A0A8C5NZB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Ndufa13
gene id: 51337:Ndufa13
uniprot id: A0A8C5LCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

51337:LOC101617678
gene id: 51337:LOC101617678
uniprot id: A0A8C5KEF9
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

51337:Mogs
gene id: 51337:Mogs
uniprot id: A0A8C5KJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

51337:Rdh10
gene id: 51337:Rdh10
uniprot id: A0A8C5KPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

51337:Sptb
gene id: 51337:Sptb
uniprot id: A0A8C5K115
names: Similarity
messages: Belongs to the spectrin family.

51337:LOC101601381
gene id: 51337:LOC101601381
uniprot id: A0A8C5L5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

51337:Ccl20
gene id: 51337:Ccl20
uniprot id: A0A8C5NZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

51337:Erbb4
gene id: 51337:Erbb4
uniprot id: A0A8C5L9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

51337:LOC101610650
gene id: 51337:LOC101610650
uniprot id: A0A8C5NUI4
names: Subcellular Location Annotation
messages: Membrane

51337:Crtc1
gene id: 51337:Crtc1
uniprot id: A0A8C5NYV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

51337:Cep57
gene id: 51337:Cep57
uniprot id: A0A8C5KL80
names: Similarity
messages: Belongs to the translokin family.

51337:Guca2a
gene id: 51337:Guca2a
uniprot id: A0A8C5K8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

51337:Arl5a
gene id: 51337:Arl5a
uniprot id: A0A8C5KT15
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

51337:Tpm4
gene id: 51337:Tpm4
uniprot id: A0A8C5L307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

51337:Cnot7
gene id: 51337:Cnot7
uniprot id: A0A8C5KIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

51337:Thoc6
gene id: 51337:Thoc6
uniprot id: A0A8C5L5U4
names: Similarity
messages: Belongs to the WD repeat THOC6 family.

51337:Hoxb5
gene id: 51337:Hoxb5
uniprot id: A0A8C5K100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Shmt2
gene id: 51337:Shmt2
uniprot id: A0A8C5K3U5
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

51337:Fgf19
gene id: 51337:Fgf19
uniprot id: A0A8C5P0B9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

51337:LOC101602130
gene id: 51337:LOC101602130
uniprot id: A0A8C5NUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Znf449
gene id: 51337:Znf449
uniprot id: A0A8C5JVN9
names: Subcellular Location Annotation
messages: Nucleus

51337:Gclm
gene id: 51337:Gclm
uniprot id: A0A8C5LFY6
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

51337:Ablim3
gene id: 51337:Ablim3
uniprot id: A0A8C5LIF7
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Pck1
gene id: 51337:Pck1
uniprot id: A0A8C5KGN4
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

51337:Cavin4
gene id: 51337:Cavin4
uniprot id: A0A8C5KGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

51337:Sart1
gene id: 51337:Sart1
uniprot id: A0A8C5P283
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

51337:Hoxa3
gene id: 51337:Hoxa3
uniprot id: A0A8C5NYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Phka1
gene id: 51337:Phka1
uniprot id: A0A8C5KTB5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

51337:Tnfrsf4
gene id: 51337:Tnfrsf4
uniprot id: A0A8C5P3P5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Ptger2
gene id: 51337:Ptger2
uniprot id: A0A8C5P5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Pacc1
gene id: 51337:Pacc1
uniprot id: A0A8C5KYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

51337:Hax1
gene id: 51337:Hax1
uniprot id: A0A8C5P3B2
names: Function
names: Similarity
messages: Belongs to the HAX1 family.
messages: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

51337:Ventx
gene id: 51337:Ventx
uniprot id: A0A8C5LF09
names: Subcellular Location Annotation
messages: Nucleus

51337:Slc6a13
gene id: 51337:Slc6a13
uniprot id: A0A8C5KEK6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Membrane

51337:Ccr10
gene id: 51337:Ccr10
uniprot id: A0A8C5L6C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Gadl1
gene id: 51337:Gadl1
uniprot id: A0A8C5LKP9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

51337:Mark2
gene id: 51337:Mark2
uniprot id: A0A8C5L1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

51337:Gna13
gene id: 51337:Gna13
uniprot id: A0A8C5KUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

51337:Nr2f6
gene id: 51337:Nr2f6
uniprot id: A0A8C5K7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

51337:Ghrhr
gene id: 51337:Ghrhr
uniprot id: A0A8C5NW37
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101593350
gene id: 51337:LOC101593350
uniprot id: A0A8C5JXD0
names: Similarity
messages: Belongs to the SLBP family.

51337:LOC105943692
gene id: 51337:LOC105943692
uniprot id: A0A8C5KEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

51337:Gabrb2
gene id: 51337:Gabrb2
uniprot id: A0A8C5LC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Manf
gene id: 51337:Manf
uniprot id: A0A8C5KWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

51337:Hyi
gene id: 51337:Hyi
uniprot id: A0A8C5KQU0
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

51337:LOC101611620
gene id: 51337:LOC101611620
uniprot id: A0A8C5KJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Usb1
gene id: 51337:Usb1
uniprot id: A0A8C5L9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.

51337:Cfap52
gene id: 51337:Cfap52
uniprot id: A0A8C5KPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP52 family.
messages: cilium axoneme
messages: flagellum

51337:Stx18
gene id: 51337:Stx18
uniprot id: A0A8C5KTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

51337:Bche
gene id: 51337:Bche
uniprot id: A0A8C5LFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

51337:Ffar1
gene id: 51337:Ffar1
uniprot id: A0A8C5K6N6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Cpsf3
gene id: 51337:Cpsf3
uniprot id: A0A8C5LDX1
names: Subcellular Location Annotation
messages: Nucleus

51337:Capns1
gene id: 51337:Capns1
uniprot id: A0A8C5LBE3
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer or heterodimer of a large (catalytic) and a small (regulatory) subunit. In presence of calcium, the heterodimer dissociates.
messages: Membrane

51337:Arcn1
gene id: 51337:Arcn1
uniprot id: A0A8C5JZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

51337:Wdr83os
gene id: 51337:Wdr83os
uniprot id: A0A8C5L5Y0
names: Similarity
messages: Belongs to the Asterix family.

51337:Zfhx4
gene id: 51337:Zfhx4
uniprot id: A0A8C5LI14
names: Subcellular Location Annotation
messages: Nucleus

51337:Zdhhc13
gene id: 51337:Zdhhc13
uniprot id: A0A8C5L8N3
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Atp5f1e
gene id: 51337:Atp5f1e
uniprot id: A0A8C5L3T4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

51337:LOC101614318
gene id: 51337:LOC101614318
uniprot id: A0A8C5KEK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

51337:Gpc1
gene id: 51337:Gpc1
uniprot id: A0A8C5P360
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

51337:Ovol3
gene id: 51337:Ovol3
uniprot id: A0A8C5KRH5
names: Subcellular Location Annotation
messages: Nucleus

51337:Bcl7c
gene id: 51337:Bcl7c
uniprot id: A0A8C5KUB2
names: Similarity
messages: Belongs to the BCL7 family.

51337:Ears2
gene id: 51337:Ears2
uniprot id: A0A8C5K2A9
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

51337:Pln
gene id: 51337:Pln
uniprot id: A0A8C5JZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

51337:Rprd1a
gene id: 51337:Rprd1a
uniprot id: A0A8C5KHK4
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

51337:Meis2
gene id: 51337:Meis2
uniprot id: A0A8C5KLM9
uniprot id: A0A8C5KNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

51337:Atp1b2
gene id: 51337:Atp1b2
uniprot id: A0A8C5KE22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

51337:Thy1
gene id: 51337:Thy1
uniprot id: A0A8C5KBN9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
messages: Membrane

51337:Cnrip1
gene id: 51337:Cnrip1
uniprot id: A0A8C5KT17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

51337:Kin
gene id: 51337:Kin
uniprot id: A0A8C5P400
names: Similarity
messages: Belongs to the KIN17 family.

51337:LOC101604622
gene id: 51337:LOC101604622
uniprot id: A0A8C5KE07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Dlgap4
gene id: 51337:Dlgap4
uniprot id: A0A8C5L308
uniprot id: A0A8C5L565
uniprot id: A0A8C5P2T2
names: Similarity
messages: Belongs to the SAPAP family.

51337:Uts2r
gene id: 51337:Uts2r
uniprot id: A0A8C5K0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

51337:Tbxa2r
gene id: 51337:Tbxa2r
uniprot id: A0A8C5KML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Hectd1
gene id: 51337:Hectd1
uniprot id: A0A8C5JYG3
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

51337:Krt17
gene id: 51337:Krt17
uniprot id: A0A8C5NW22
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Foxo3
gene id: 51337:Foxo3
uniprot id: A0A8C5JWV4
names: Subcellular Location Annotation
messages: Nucleus

51337:Sema3d
gene id: 51337:Sema3d
uniprot id: A0A8C5L7L4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Plpp2
gene id: 51337:Plpp2
uniprot id: A0A8C5LG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

51337:Gjb5
gene id: 51337:Gjb5
uniprot id: A0A8C5K7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Rdh14
gene id: 51337:Rdh14
uniprot id: A0A8C5LDE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Ppie
gene id: 51337:Ppie
uniprot id: A0A8C5LCF0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

51337:Fam83f
gene id: 51337:Fam83f
uniprot id: A0A8C5KDR8
names: Similarity
messages: Belongs to the FAM83 family.

51337:Foxa1
gene id: 51337:Foxa1
uniprot id: A0A8C5NUE2
names: Subcellular Location Annotation
messages: Nucleus

51337:Aqp7
gene id: 51337:Aqp7
uniprot id: A0A8C5KBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

51337:Dnm1l
gene id: 51337:Dnm1l
uniprot id: A0A8C5LC34
uniprot id: A0A8C5LH49
uniprot id: A0A8C5LK07
uniprot id: A0A8C5P4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

51337:Aass
gene id: 51337:Aass
uniprot id: A0A8C5JY36
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

51337:LOC101598231
gene id: 51337:LOC101598231
uniprot id: A0A8C5K024
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:LOC101610007
gene id: 51337:LOC101610007
uniprot id: A0A8C5NW06
names: Similarity
messages: Belongs to the PHYHIP family.

51337:Prpf4
gene id: 51337:Prpf4
uniprot id: A0A8C5K410
names: Subcellular Location Annotation
messages: Nucleus speckle

51337:Rpl10a
gene id: 51337:Rpl10a
uniprot id: A0A8C5KKL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

51337:Gpi
gene id: 51337:Gpi
uniprot id: A0A8C5K4Q1
names: Similarity
messages: Belongs to the GPI family.

51337:Plaa
gene id: 51337:Plaa
uniprot id: A0A8C5KG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

51337:Man2c1
gene id: 51337:Man2c1
uniprot id: A0A8C5LD85
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

51337:Pnkd
gene id: 51337:Pnkd
uniprot id: A0A8C5LED2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

51337:Dusp4
gene id: 51337:Dusp4
uniprot id: A0A8C5KSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

51337:LOC101601029
gene id: 51337:LOC101601029
uniprot id: A0A8C5K6R3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

51337:Psme3
gene id: 51337:Psme3
uniprot id: A0A8C5L3K5
names: Similarity
messages: Belongs to the PA28 family.

51337:Zdhhc15
gene id: 51337:Zdhhc15
uniprot id: A0A8C5L8Y1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Ywhae
gene id: 51337:Ywhae
uniprot id: A0A8C5KR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

51337:LOC105943588
gene id: 51337:LOC105943588
uniprot id: A0A8C5KR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

51337:Nmnat3
gene id: 51337:Nmnat3
uniprot id: A0A8C5JU80
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

51337:Dgkq
gene id: 51337:Dgkq
uniprot id: A0A8C5JWW2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

51337:LOC101613690
gene id: 51337:LOC101613690
uniprot id: A0A8C5JYE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

51337:LOC101609771
gene id: 51337:LOC101609771
uniprot id: A0A8C5KFQ8
names: Subcellular Location Annotation
messages: extracellular matrix

51337:Gpc6
gene id: 51337:Gpc6
uniprot id: A0A8C5KM90
uniprot id: A0A8C5KU26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

51337:Krt35
gene id: 51337:Krt35
uniprot id: A0A8C5P4B9
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Mrpl2
gene id: 51337:Mrpl2
uniprot id: A0A8C5K4G5
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

51337:Slc25a37
gene id: 51337:Slc25a37
uniprot id: A0A8C5KDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Aga
gene id: 51337:Aga
uniprot id: A0A8C5LHP2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

51337:Rprm
gene id: 51337:Rprm
uniprot id: A0A8C5KBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

51337:Erg
gene id: 51337:Erg
uniprot id: A0A8C5LM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Pitx3
gene id: 51337:Pitx3
uniprot id: A0A8C5L9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

51337:Mxra8
gene id: 51337:Mxra8
uniprot id: A0A8C5L1Z6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Plk3
gene id: 51337:Plk3
uniprot id: A0A8C5KLW0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

51337:Fat2
gene id: 51337:Fat2
uniprot id: A0A8C5P376
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Abi2
gene id: 51337:Abi2
uniprot id: A0A8C5K3G0
uniprot id: A0A8C5K4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

51337:LOC101604989
gene id: 51337:LOC101604989
uniprot id: A0A8C5KAF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Ppfia4
gene id: 51337:Ppfia4
uniprot id: A0A8C5K9X9
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

51337:C1H4orf47
gene id: 51337:C1H4orf47
uniprot id: A0A8C5KVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

51337:Mrpl53
gene id: 51337:Mrpl53
uniprot id: A0A8C5KDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

51337:Gata3
gene id: 51337:Gata3
uniprot id: A0A8C5P662
names: Subcellular Location Annotation
messages: Nucleus

51337:Hoxc9
gene id: 51337:Hoxc9
uniprot id: A0A8C5P3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

51337:Glb1l2
gene id: 51337:Glb1l2
uniprot id: A0A8C5KYT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

51337:LOC101596217
gene id: 51337:LOC101596217
uniprot id: A0A8C5P388
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

51337:Serpinb9
gene id: 51337:Serpinb9
uniprot id: A0A8C5L0U6
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

51337:Fmo1
gene id: 51337:Fmo1
uniprot id: A0A8C5K0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.

51337:Virma
gene id: 51337:Virma
uniprot id: A0A8C5LNK2
names: Similarity
messages: Belongs to the vir family.

51337:Hoxc11
gene id: 51337:Hoxc11
uniprot id: A0A8C5K4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

51337:Arl4d
gene id: 51337:Arl4d
uniprot id: A0A8C5NV46
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

51337:Avpr2
gene id: 51337:Avpr2
uniprot id: A0A8C5KZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
messages: Membrane

51337:Axin2
gene id: 51337:Axin2
uniprot id: A0A8C5P0H5
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Slc44a2
gene id: 51337:Slc44a2
uniprot id: A0A8C5KC79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

51337:Mafb
gene id: 51337:Mafb
uniprot id: A0A8C5KHF3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

51337:Get3
gene id: 51337:Get3
uniprot id: A0A8C5KSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

51337:Trim36
gene id: 51337:Trim36
uniprot id: A0A8C5KTL8
uniprot id: A0A8C5KW30
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Rbm8a
gene id: 51337:Rbm8a
uniprot id: A0A8C5K6X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

51337:Defb129
gene id: 51337:Defb129
uniprot id: A0A8C5KZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

51337:Prps2
gene id: 51337:Prps2
uniprot id: A0A8C5K1A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

51337:Tspan18
gene id: 51337:Tspan18
uniprot id: A0A8C5K657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Grik2
gene id: 51337:Grik2
uniprot id: A0A8C5L103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Cryba2
gene id: 51337:Cryba2
uniprot id: A0A8C5KC54
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Gabra5
gene id: 51337:Gabra5
uniprot id: A0A8C5KFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Cetn2
gene id: 51337:Cetn2
uniprot id: A0A8C5NZ13
names: Similarity
messages: Belongs to the centrin family.

51337:Dok3
gene id: 51337:Dok3
uniprot id: A0A8C5K1R6
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

51337:Cops2
gene id: 51337:Cops2
uniprot id: A0A8C5KG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

51337:LOC101611959
gene id: 51337:LOC101611959
uniprot id: A0A8C5P2A8
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Haus3
gene id: 51337:Haus3
uniprot id: A0A8C5NYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

51337:Bcap31
gene id: 51337:Bcap31
uniprot id: A0A8C5KD41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

51337:Nnmt
gene id: 51337:Nnmt
uniprot id: A0A8C5P119
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

51337:Tram2
gene id: 51337:Tram2
uniprot id: A0A8C5P2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

51337:Tm2d2
gene id: 51337:Tm2d2
uniprot id: A0A8C5L641
names: Subcellular Location Annotation
messages: Membrane

51337:Gapdh
gene id: 51337:Gapdh
uniprot id: A0A8C5KRS6
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

51337:Bpifa1
gene id: 51337:Bpifa1
uniprot id: A0A8C5LB16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
messages: Monomer. Interacts (via N-terminus) with SCNN1B, a subunit of the heterotrimeric epithelial sodium channel (ENaC); this inhibits proteolytic activation of ENaC.
messages: Secreted

51337:Ifih1
gene id: 51337:Ifih1
uniprot id: A0A8C5L2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

51337:LOC101610563
gene id: 51337:LOC101610563
uniprot id: A0A8C5KFV9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

51337:Gja3
gene id: 51337:Gja3
uniprot id: A0A8C5KA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Dram2
gene id: 51337:Dram2
uniprot id: A0A8C5KKY2
names: Subcellular Location Annotation
messages: Membrane

51337:Hoxc13
gene id: 51337:Hoxc13
uniprot id: A0A8C5LFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

51337:Kcnc1
gene id: 51337:Kcnc1
uniprot id: A0A8C5L6H3
names: Subcellular Location Annotation
messages: Membrane

51337:B3gat3
gene id: 51337:B3gat3
uniprot id: A0A8C5LLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Scg3
gene id: 51337:Scg3
uniprot id: A0A8C5KJ98
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

51337:Septin6
gene id: 51337:Septin6
uniprot id: A0A8C5L7P7
uniprot id: A0A8C5LAQ8
uniprot id: A0A8C5P3J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

51337:Mpv17l2
gene id: 51337:Mpv17l2
uniprot id: A0A8C5KUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

51337:Cdc42ep2
gene id: 51337:Cdc42ep2
uniprot id: A0A8C5K7V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system
messages: Probably involved in the organization of the actin cytoskeleton.
messages: cytoskeleton

51337:Itga4
gene id: 51337:Itga4
uniprot id: A0A8C5L8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

51337:Rsl24d1
gene id: 51337:Rsl24d1
uniprot id: A0A8C5K7G6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

51337:Scarb1
gene id: 51337:Scarb1
uniprot id: A0A8C5KY81
names: Similarity
messages: Belongs to the CD36 family.

51337:Snrpd3
gene id: 51337:Snrpd3
uniprot id: A0A8C5KFH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
messages: cytosol

51337:Kcnj13
gene id: 51337:Kcnj13
uniprot id: A0A8C5KXR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

51337:Zhx2
gene id: 51337:Zhx2
uniprot id: A0A8C5JXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

51337:Adam10
gene id: 51337:Adam10
uniprot id: A0A8C5L4J2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: adherens junction

51337:Acads
gene id: 51337:Acads
uniprot id: A0A8C5L3D3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

51337:LOC101609153
gene id: 51337:LOC101609153
uniprot id: A0A8C5KZR0
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:LOC101613358
gene id: 51337:LOC101613358
uniprot id: A0A8C5P1X8
names: Similarity
messages: Belongs to the aldo/keto reductase family.

51337:Kif20a
gene id: 51337:Kif20a
uniprot id: A0A8C5L9A6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Pmp22
gene id: 51337:Pmp22
uniprot id: A0A8C5KJ87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

51337:Snrpg
gene id: 51337:Snrpg
uniprot id: A0A8C5KLF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

51337:Eda2r
gene id: 51337:Eda2r
uniprot id: A0A8C5K8A3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Cadm3
gene id: 51337:Cadm3
uniprot id: A0A8C5LBI2
uniprot id: A0A8C5P4M2
names: Similarity
messages: Belongs to the nectin family.

51337:Ldb2
gene id: 51337:Ldb2
uniprot id: A0A8C5KP89
names: Similarity
messages: Belongs to the LDB family.

51337:Hephl1
gene id: 51337:Hephl1
uniprot id: A0A8C5KS13
names: Similarity
messages: Belongs to the multicopper oxidase family.

51337:Rps6
gene id: 51337:Rps6
uniprot id: A0A8C5KB75
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

51337:Grin3a
gene id: 51337:Grin3a
uniprot id: A0A8C5LMI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Gtf3c5
gene id: 51337:Gtf3c5
uniprot id: A0A8C5LHN2
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101616030
gene id: 51337:LOC101616030
uniprot id: A0A8C5NX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM24 family.
messages: Secreted

51337:Ppa1
gene id: 51337:Ppa1
uniprot id: A0A8C5LD35
names: Similarity
messages: Belongs to the PPase family.

51337:Ap3b1
gene id: 51337:Ap3b1
uniprot id: A0A8C5KWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

51337:Elavl1
gene id: 51337:Elavl1
uniprot id: A0A8C5KSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

51337:Clstn3
gene id: 51337:Clstn3
uniprot id: A0A8C5KIQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

51337:Arrb2
gene id: 51337:Arrb2
uniprot id: A0A8C5L2F1
names: Similarity
messages: Belongs to the arrestin family.

51337:Acad11
gene id: 51337:Acad11
uniprot id: A0A8C5K1F8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

51337:Gpx8
gene id: 51337:Gpx8
uniprot id: A0A8C5LID5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

51337:LOC101593771
gene id: 51337:LOC101593771
uniprot id: A0A8C5KIF0
names: Subcellular Location Annotation
messages: Membrane

51337:Pus1
gene id: 51337:Pus1
uniprot id: A0A8C5JUV5
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

51337:Rab38
gene id: 51337:Rab38
uniprot id: A0A8C5L556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

51337:Clcn5
gene id: 51337:Clcn5
uniprot id: A0A8C5KQT3
uniprot id: A0A8C5NZV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Ep300
gene id: 51337:Ep300
uniprot id: A0A8C5L6M5
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Naif1
gene id: 51337:Naif1
uniprot id: A0A8C5NZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

51337:Insr
gene id: 51337:Insr
uniprot id: A0A8C5LET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

51337:LOC101604520
gene id: 51337:LOC101604520
uniprot id: A0A8C5L7L1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Mcm6
gene id: 51337:Mcm6
uniprot id: A0A8C5K5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

51337:Slc9a2
gene id: 51337:Slc9a2
uniprot id: A0A8C5KNP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Interacts with CHP1 and CHP2.
messages: Membrane

51337:Reep2
gene id: 51337:Reep2
uniprot id: A0A8C5LHP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Xpnpep2
gene id: 51337:Xpnpep2
uniprot id: A0A8C5L4H3
names: Similarity
messages: Belongs to the peptidase M24B family.

51337:Cebpe
gene id: 51337:Cebpe
uniprot id: A0A8C5JX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

51337:Prdx6
gene id: 51337:Prdx6
uniprot id: A0A8C5L6D1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

51337:Usp5
gene id: 51337:Usp5
uniprot id: A0A8C5LDH9
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

51337:Gpr52
gene id: 51337:Gpr52
uniprot id: A0A8C5KAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Asic2
gene id: 51337:Asic2
uniprot id: A0A8C5KZ93
names: Subcellular Location Annotation
messages: Membrane

51337:Ccng2
gene id: 51337:Ccng2
uniprot id: A0A8C5KK88
names: Similarity
messages: Belongs to the cyclin family.

51337:Fn3k
gene id: 51337:Fn3k
uniprot id: A0A8C5LH63
names: Similarity
messages: Belongs to the fructosamine kinase family.

51337:Lyrm4
gene id: 51337:Lyrm4
uniprot id: A0A8C5JZE8
names: Similarity
messages: Belongs to the complex I LYR family.

51337:Lage3
gene id: 51337:Lage3
uniprot id: A0A8C5LD34
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

51337:Galntl6
gene id: 51337:Galntl6
uniprot id: A0A8C5L754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Prpf19
gene id: 51337:Prpf19
uniprot id: A0A8C5P392
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

51337:Ngf
gene id: 51337:Ngf
uniprot id: A0A8C5LB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

51337:Peds1
gene id: 51337:Peds1
uniprot id: A0A8C5JZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

51337:Lypla2
gene id: 51337:Lypla2
uniprot id: A0A8C5K244
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

51337:S100z
gene id: 51337:S100z
uniprot id: A0A8C5KF89
names: Similarity
messages: Belongs to the S-100 family.

51337:Arsg
gene id: 51337:Arsg
uniprot id: A0A8C5LCI4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Tmem198
gene id: 51337:Tmem198
uniprot id: A0A8C5LJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

51337:Ing3
gene id: 51337:Ing3
uniprot id: A0A8C5K1F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

51337:Krt18
gene id: 51337:Krt18
uniprot id: A0A8C5K0B8
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Nono
gene id: 51337:Nono
uniprot id: A0A8C5KSM6
names: Subcellular Location Annotation
messages: Nucleus speckle

51337:Pgm5
gene id: 51337:Pgm5
uniprot id: A0A8C5LFE4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

51337:Plppr4
gene id: 51337:Plppr4
uniprot id: A0A8C5P275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

51337:Akap13
gene id: 51337:Akap13
uniprot id: A0A8C5LBB1
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Paf1
gene id: 51337:Paf1
uniprot id: A0A8C5NXD6
names: Similarity
messages: Belongs to the PAF1 family.

51337:Fyn
gene id: 51337:Fyn
uniprot id: A0A8C5L4Q7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:Grm7
gene id: 51337:Grm7
uniprot id: A0A8C5LE78
uniprot id: A0A8C5P5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

51337:Cstf1
gene id: 51337:Cstf1
uniprot id: A0A8C5KUR2
names: Subcellular Location Annotation
messages: Nucleus

51337:Fut11
gene id: 51337:Fut11
uniprot id: A0A8C5KMR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

51337:Ndufs3
gene id: 51337:Ndufs3
uniprot id: A0A8C5LL83
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

51337:Bgn
gene id: 51337:Bgn
uniprot id: A0A8C5KNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

51337:Arsk
gene id: 51337:Arsk
uniprot id: A0A8C5L5Z7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:LOC101609016
gene id: 51337:LOC101609016
uniprot id: A0A8C5K2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Fkbp4
gene id: 51337:Fkbp4
uniprot id: A0A8C5KU62
names: Subcellular Location Annotation
messages: Nucleus

51337:Rpl30
gene id: 51337:Rpl30
uniprot id: A0A8C5LDE8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

51337:LOC101616519
gene id: 51337:LOC101616519
uniprot id: A0A8C5NX27
names: Similarity
messages: Belongs to the HPF1 family.

51337:Bpnt2
gene id: 51337:Bpnt2
uniprot id: A0A8C5KUB8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

51337:Fcgrt
gene id: 51337:Fcgrt
uniprot id: A0A8C5P5D1
names: Subcellular Location Annotation
messages: Membrane

51337:Pex10
gene id: 51337:Pex10
uniprot id: A0A8C5KT93
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

51337:Cul9
gene id: 51337:Cul9
uniprot id: A0A8C5KHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

51337:Galnt15
gene id: 51337:Galnt15
uniprot id: A0A8C5KZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:LOC101611834
gene id: 51337:LOC101611834
uniprot id: A0A8C5KEH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Patz1
gene id: 51337:Patz1
uniprot id: A0A8C5KQ55
uniprot id: A0A8C5KQ64
uniprot id: A0A8C5KS86
names: Subcellular Location Annotation
messages: Nucleus

51337:Kcnk10
gene id: 51337:Kcnk10
uniprot id: A0A8C5LF23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

51337:Ptger4
gene id: 51337:Ptger4
uniprot id: A0A8C5LGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

51337:Fmo2
gene id: 51337:Fmo2
uniprot id: A0A8C5L1F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

51337:Epha4
gene id: 51337:Epha4
uniprot id: A0A8C5LD47
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

51337:Irx5
gene id: 51337:Irx5
uniprot id: A0A8C5P0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

51337:Ca3
gene id: 51337:Ca3
uniprot id: A0A8C5LFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

51337:Camk1g
gene id: 51337:Camk1g
uniprot id: A0A8C5K1Y2
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Ssu72
gene id: 51337:Ssu72
uniprot id: A0A8C5K6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

51337:LOC101598678
gene id: 51337:LOC101598678
uniprot id: A0A8C5KQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Wars2
gene id: 51337:Wars2
uniprot id: A0A8C5JWM7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Sgsm2
gene id: 51337:Sgsm2
uniprot id: A0A8C5KUL9
names: Similarity
messages: Belongs to the RUTBC family.

51337:Cnn1
gene id: 51337:Cnn1
uniprot id: A0A8C5JYV4
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

51337:Htr2a
gene id: 51337:Htr2a
uniprot id: A0A8C5K539
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

51337:LOC101610718
gene id: 51337:LOC101610718
uniprot id: A0A8C5NZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

51337:Spry2
gene id: 51337:Spry2
uniprot id: A0A8C5NZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: ruffle membrane

51337:Antxr1
gene id: 51337:Antxr1
uniprot id: A0A8C5KFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

51337:Ewsr1
gene id: 51337:Ewsr1
uniprot id: A0A8C5JY63
uniprot id: A0A8C5JZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

51337:LOC101606708
gene id: 51337:LOC101606708
uniprot id: A0A8C5JZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

51337:Ypel2
gene id: 51337:Ypel2
uniprot id: A0A8C5KH36
names: Similarity
messages: Belongs to the yippee family.

51337:Flvcr2
gene id: 51337:Flvcr2
uniprot id: A0A8C5KCS0
names: Subcellular Location Annotation
messages: Membrane

51337:Slc10a2
gene id: 51337:Slc10a2
uniprot id: A0A8C5LCW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

51337:Sub1
gene id: 51337:Sub1
uniprot id: A0A8C5L2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

51337:Trmu
gene id: 51337:Trmu
uniprot id: A0A8C5K0V4
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

51337:Alcam
gene id: 51337:Alcam
uniprot id: A0A8C5LEP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

51337:Nrm
gene id: 51337:Nrm
uniprot id: A0A8C5P641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

51337:Mfn2
gene id: 51337:Mfn2
uniprot id: A0A8C5KET3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

51337:Pou3f4
gene id: 51337:Pou3f4
uniprot id: A0A8C5KHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

51337:Trpt1
gene id: 51337:Trpt1
uniprot id: A0A8C5K7R5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

51337:Cda
gene id: 51337:Cda
uniprot id: A0A8C5LG56
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

51337:Slc4a10
gene id: 51337:Slc4a10
uniprot id: A0A8C5KM18
uniprot id: A0A8C5KQ36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Rad54l2
gene id: 51337:Rad54l2
uniprot id: A0A8C5KHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

51337:Slc5a11
gene id: 51337:Slc5a11
uniprot id: A0A8C5KCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:Ftcd
gene id: 51337:Ftcd
uniprot id: A0A8C5JXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

51337:Ndufaf1
gene id: 51337:Ndufaf1
uniprot id: A0A8C5JY50
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

51337:LOC101609152
gene id: 51337:LOC101609152
uniprot id: A0A8C5K9K9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

51337:Ptcd2
gene id: 51337:Ptcd2
uniprot id: A0A8C5LI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

51337:Gpr22
gene id: 51337:Gpr22
uniprot id: A0A8C5LAI8
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101609411
gene id: 51337:LOC101609411
uniprot id: A0A8C5NUX1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

51337:LOC101595240
gene id: 51337:LOC101595240
uniprot id: A0A8C5KHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Tars1
gene id: 51337:Tars1
uniprot id: A0A8C5KGZ3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

51337:Mrgprf
gene id: 51337:Mrgprf
uniprot id: A0A8C5KVV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Ncam1
gene id: 51337:Ncam1
uniprot id: A0A8C5P3I6
names: Function
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

51337:Hgd
gene id: 51337:Hgd
uniprot id: A0A8C5JUT5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

51337:Wnt1
gene id: 51337:Wnt1
uniprot id: A0A8C5L4L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Rab3a
gene id: 51337:Rab3a
uniprot id: A0A8C5P284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

51337:Pi4k2a
gene id: 51337:Pi4k2a
uniprot id: A0A8C5P460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

51337:Cdo1
gene id: 51337:Cdo1
uniprot id: A0A8C5K7X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

51337:Fshr
gene id: 51337:Fshr
uniprot id: A0A8C5KS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

51337:Fam229a
gene id: 51337:Fam229a
uniprot id: A0A8C5LIL5
names: Similarity
messages: Belongs to the FAM229 family.

51337:Cdc20
gene id: 51337:Cdc20
uniprot id: A0A8C5L358
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

51337:Lamc1
gene id: 51337:Lamc1
uniprot id: A0A8C5JY97
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

51337:Pon3
gene id: 51337:Pon3
uniprot id: A0A8C5KNE1
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

51337:Pkp1
gene id: 51337:Pkp1
uniprot id: A0A8C5K2C1
names: Similarity
messages: Belongs to the beta-catenin family.

51337:Vdac2
gene id: 51337:Vdac2
uniprot id: A0A8C5KJL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

51337:Bicd2
gene id: 51337:Bicd2
uniprot id: A0A8C5KV80
names: Similarity
messages: Belongs to the BicD family.

51337:Zdhhc7
gene id: 51337:Zdhhc7
uniprot id: A0A8C5NWU4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

51337:Prop1
gene id: 51337:Prop1
uniprot id: A0A8C5L017
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

51337:Extl3
gene id: 51337:Extl3
uniprot id: A0A8C5KIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Gdf6
gene id: 51337:Gdf6
uniprot id: A0A8C5P0T7
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Onecut1
gene id: 51337:Onecut1
uniprot id: A0A8C5L6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

51337:Tmem80
gene id: 51337:Tmem80
uniprot id: A0A8C5JYJ3
names: Subcellular Location Annotation
messages: Membrane

51337:Arf3
gene id: 51337:Arf3
uniprot id: A0A8C5L4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

51337:Poll
gene id: 51337:Poll
uniprot id: A0A8C5LLM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

51337:Trpv2
gene id: 51337:Trpv2
uniprot id: A0A8C5KSG6
names: Subcellular Location Annotation
messages: Membrane

51337:Dazap2
gene id: 51337:Dazap2
uniprot id: A0A8C5KZX1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

51337:Mapk10
gene id: 51337:Mapk10
uniprot id: A0A8C5LFM5
uniprot id: A0A8C5P4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

51337:LOC101602655
gene id: 51337:LOC101602655
uniprot id: A0A8C5K881
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

51337:Trappc2l
gene id: 51337:Trappc2l
uniprot id: A0A8C5KWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

51337:Naprt
gene id: 51337:Naprt
uniprot id: A0A8C5LJ95
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

51337:Fzd4
gene id: 51337:Fzd4
uniprot id: A0A8C5K3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

51337:Acy1
gene id: 51337:Acy1
uniprot id: A0A8C5L6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Cytoplasm

51337:Tgfb2
gene id: 51337:Tgfb2
uniprot id: A0A8C5KQR8
uniprot id: A0A8C5KU92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

51337:Hs3st5
gene id: 51337:Hs3st5
uniprot id: A0A8C5P051
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:LOC101611787
gene id: 51337:LOC101611787
uniprot id: A0A8C5KMC2
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Tmem97
gene id: 51337:Tmem97
uniprot id: A0A8C5NVC2
names: Subcellular Location Annotation
messages: Membrane

51337:Cryab
gene id: 51337:Cryab
uniprot id: A0A8C5LH22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

51337:Fis1
gene id: 51337:Fis1
uniprot id: A0A8C5LCM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

51337:Steep1
gene id: 51337:Steep1
uniprot id: A0A8C5LBJ6
names: Similarity
messages: Belongs to the STEEP1 family.

51337:Madd
gene id: 51337:Madd
uniprot id: A0A8C5KTW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

51337:Ndufaf4
gene id: 51337:Ndufaf4
uniprot id: A0A8C5LK09
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

51337:Sgk1
gene id: 51337:Sgk1
uniprot id: A0A8C5JXZ2
uniprot id: A0A8C5JZG8
uniprot id: A0A8C5K0U4
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Tekt3
gene id: 51337:Tekt3
uniprot id: A0A8C5L2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

51337:Dgat2
gene id: 51337:Dgat2
uniprot id: A0A8C5L5E5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Mrpl23
gene id: 51337:Mrpl23
uniprot id: A0A8C5K0E7
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

51337:Pard3
gene id: 51337:Pard3
uniprot id: A0A8C5KSA9
uniprot id: A0A8C5KWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

51337:Alkal2
gene id: 51337:Alkal2
uniprot id: A0A8C5KRQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

51337:Atp10b
gene id: 51337:Atp10b
uniprot id: A0A8C5KLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

51337:Asb6
gene id: 51337:Asb6
uniprot id: A0A8C5NVC3
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

51337:Septin4
gene id: 51337:Septin4
uniprot id: A0A8C5LAJ7
uniprot id: A0A8C5LFE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

51337:Pfn1
gene id: 51337:Pfn1
uniprot id: A0A8C5KWF1
names: Similarity
messages: Belongs to the profilin family.

51337:Prpf18
gene id: 51337:Prpf18
uniprot id: A0A8C5P614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

51337:Hspb8
gene id: 51337:Hspb8
uniprot id: A0A8C5LNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Displays temperature-dependent chaperone activity.
messages: Nucleus

51337:Cd44
gene id: 51337:Cd44
uniprot id: A0A8C5LH56
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

51337:Uxs1
gene id: 51337:Uxs1
uniprot id: A0A8C5P525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

51337:Palmd
gene id: 51337:Palmd
uniprot id: A0A8C5NYU3
names: Similarity
messages: Belongs to the paralemmin family.

51337:LOC105944014
gene id: 51337:LOC105944014
uniprot id: A0A8C5K2Y9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

51337:Cdk8
gene id: 51337:Cdk8
uniprot id: A0A8C5NWE9
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Bola1
gene id: 51337:Bola1
uniprot id: A0A8C5L0N7
names: Similarity
messages: Belongs to the BolA/IbaG family.

51337:Slc8a2
gene id: 51337:Slc8a2
uniprot id: A0A8C5KIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

51337:Gadd45g
gene id: 51337:Gadd45g
uniprot id: A0A8C5JXU6
names: Similarity
messages: Belongs to the GADD45 family.

51337:LOC101602722
gene id: 51337:LOC101602722
uniprot id: A0A8C5KP56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

51337:Tsen54
gene id: 51337:Tsen54
uniprot id: A0A8C5NVM3
names: Similarity
messages: Belongs to the SEN54 family.

51337:Vps13c
gene id: 51337:Vps13c
uniprot id: A0A8C5KH10
names: Similarity
messages: Belongs to the VPS13 family.

51337:LOC101602213
gene id: 51337:LOC101602213
uniprot id: A0A8C5LMQ5
names: Similarity
messages: Belongs to the BEX family.

51337:LOC101617561
gene id: 51337:LOC101617561
uniprot id: A0A8C5KJU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Gpr26
gene id: 51337:Gpr26
uniprot id: A0A8C5LF52
names: Subcellular Location Annotation
messages: Membrane

51337:Wnt16
gene id: 51337:Wnt16
uniprot id: A0A8C5KNP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Mterf2
gene id: 51337:Mterf2
uniprot id: A0A8C5K255
names: Similarity
messages: Belongs to the mTERF family.

51337:Ints3
gene id: 51337:Ints3
uniprot id: A0A8C5L2K7
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

51337:Ptk6
gene id: 51337:Ptk6
uniprot id: A0A8C5P350
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

51337:LOC101607997
gene id: 51337:LOC101607997
uniprot id: A0A8C5KCN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm

51337:Leap2
gene id: 51337:Leap2
uniprot id: A0A8C5JUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

51337:Smarca4
gene id: 51337:Smarca4
uniprot id: A0A8C5KH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

51337:Alg11
gene id: 51337:Alg11
uniprot id: A0A8C5L6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

51337:Eps8l2
gene id: 51337:Eps8l2
uniprot id: A0A8C5LEG9
names: Similarity
messages: Belongs to the EPS8 family.

51337:Cnr2
gene id: 51337:Cnr2
uniprot id: A0A8C5K2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tbpl1
gene id: 51337:Tbpl1
uniprot id: A0A8C5K3S3
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

51337:Slc16a5
gene id: 51337:Slc16a5
uniprot id: A0A8C5LG74
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101593595
gene id: 51337:LOC101593595
uniprot id: A0A8C5KJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Postn
gene id: 51337:Postn
uniprot id: A0A8C5KXB9
names: Subcellular Location Annotation
messages: extracellular matrix

51337:Pcyt2
gene id: 51337:Pcyt2
uniprot id: A0A8C5KGY9
names: Similarity
messages: Belongs to the cytidylyltransferase family.

51337:Cdk5
gene id: 51337:Cdk5
uniprot id: A0A8C5L543
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Exoc3l1
gene id: 51337:Exoc3l1
uniprot id: A0A8C5L680
names: Similarity
messages: Belongs to the SEC6 family.

51337:LOC101604522
gene id: 51337:LOC101604522
uniprot id: A0A8C5L9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

51337:LOC101606316
gene id: 51337:LOC101606316
uniprot id: A0A8C5KAK0
names: Similarity
messages: Belongs to the SNF7 family.

51337:Ap4b1
gene id: 51337:Ap4b1
uniprot id: A0A8C5L879
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

51337:Pfkfb3
gene id: 51337:Pfkfb3
uniprot id: A0A8C5LAU6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

51337:Nfx1
gene id: 51337:Nfx1
uniprot id: A0A8C5LG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

51337:LOC101594412
gene id: 51337:LOC101594412
uniprot id: A0A8C5KDK7
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

51337:Dhx29
gene id: 51337:Dhx29
uniprot id: A0A8C5LKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC) that contains at least Met-tRNA, EIF1, EIF1A (EIF1AX or EIF1AY), EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, DHX29 and the 40S ribosomal subunit.

51337:Camk2g
gene id: 51337:Camk2g
uniprot id: A0A8C5KIR8
uniprot id: A0A8C5KL39
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

51337:LOC101608939
gene id: 51337:LOC101608939
uniprot id: A0A8C5KGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Zranb2
gene id: 51337:Zranb2
uniprot id: A0A8C5LJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: Nucleus
messages: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.

51337:Ccs
gene id: 51337:Ccs
uniprot id: A0A8C5KLD0
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

51337:LOC101615027
gene id: 51337:LOC101615027
uniprot id: A0A8C5KS11
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

51337:Rpl7a
gene id: 51337:Rpl7a
uniprot id: A0A8C5P4F6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

51337:Plppr3
gene id: 51337:Plppr3
uniprot id: A0A8C5KJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

51337:Paqr4
gene id: 51337:Paqr4
uniprot id: A0A8C5K4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

51337:Tafa2
gene id: 51337:Tafa2
uniprot id: A0A8C5P2I5
names: Similarity
messages: Belongs to the TAFA family.

51337:Aspa
gene id: 51337:Aspa
uniprot id: A0A8C5LBD8
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

51337:Pitx1
gene id: 51337:Pitx1
uniprot id: A0A8C5L4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

51337:LOC101614089
gene id: 51337:LOC101614089
uniprot id: A0A8C5KAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

51337:Ogfod1
gene id: 51337:Ogfod1
uniprot id: A0A8C5P0L9
names: Similarity
messages: Belongs to the TPA1 family.

51337:Runx1
gene id: 51337:Runx1
uniprot id: A0A8C5L8L7
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

51337:Gbx2
gene id: 51337:Gbx2
uniprot id: A0A8C5KCQ6
names: Subcellular Location Annotation
messages: Nucleus

51337:Slc25a34
gene id: 51337:Slc25a34
uniprot id: A0A8C5K2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Best4
gene id: 51337:Best4
uniprot id: A0A8C5KRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

51337:Aldh1a2
gene id: 51337:Aldh1a2
uniprot id: A0A8C5P2P2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

51337:Ran
gene id: 51337:Ran
uniprot id: A0A8C5KDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

51337:Cd37
gene id: 51337:Cd37
uniprot id: A0A8C5K9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Krt8
gene id: 51337:Krt8
uniprot id: A0A8C5P0I3
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Gsk3b
gene id: 51337:Gsk3b
uniprot id: A0A8C5K715
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

51337:Lancl3
gene id: 51337:Lancl3
uniprot id: A0A8C5P4T3
names: Similarity
messages: Belongs to the LanC-like protein family.

51337:Lrrc8e
gene id: 51337:Lrrc8e
uniprot id: A0A8C5JWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

51337:Tspan7
gene id: 51337:Tspan7
uniprot id: A0A8C5KW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

51337:Sec22b
gene id: 51337:Sec22b
uniprot id: A0A8C5NX50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

51337:Paqr7
gene id: 51337:Paqr7
uniprot id: A0A8C5K535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

51337:Mmachc
gene id: 51337:Mmachc
uniprot id: A0A8C5KK35
names: Similarity
messages: Belongs to the MMACHC family.

51337:Sv2a
gene id: 51337:Sv2a
uniprot id: A0A8C5L5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

51337:LOC101602689
gene id: 51337:LOC101602689
uniprot id: A0A8C5JZX7
names: Subunit
messages: Interacts with hair keratins.

51337:Tdp2
gene id: 51337:Tdp2
uniprot id: A0A8C5LAH6
names: Subcellular Location Annotation
messages: PML body

51337:Gcgr
gene id: 51337:Gcgr
uniprot id: A0A8C5K3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

51337:Eif2b4
gene id: 51337:Eif2b4
uniprot id: A0A8C5KSC7
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

51337:Exosc2
gene id: 51337:Exosc2
uniprot id: A0A8C5K197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

51337:Hcn4
gene id: 51337:Hcn4
uniprot id: A0A8C5KCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

51337:Slc5a6
gene id: 51337:Slc5a6
uniprot id: A0A8C5K838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:Rfc4
gene id: 51337:Rfc4
uniprot id: A0A8C5KKM0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

51337:Hhex
gene id: 51337:Hhex
uniprot id: A0A8C5LB61
names: Subcellular Location Annotation
messages: Nucleus

51337:Nus1
gene id: 51337:Nus1
uniprot id: A0A8C5KZ44
names: Similarity
messages: Belongs to the UPP synthase family.

51337:LOC101606113
gene id: 51337:LOC101606113
uniprot id: A0A8C5KWG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

51337:Atm
gene id: 51337:Atm
uniprot id: A0A8C5LAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Cytoplasmic vesicle
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks.

51337:Exoc7
gene id: 51337:Exoc7
uniprot id: A0A8C5KC03
uniprot id: A0A8C5NWZ3
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

51337:Gjb4
gene id: 51337:Gjb4
uniprot id: A0A8C5K6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Klhl21
gene id: 51337:Klhl21
uniprot id: A0A8C5KLC7
names: Subcellular Location Annotation
messages: spindle

51337:Stom
gene id: 51337:Stom
uniprot id: A0A8C5KKY6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

51337:Atp6v0a1
gene id: 51337:Atp6v0a1
uniprot id: A0A8C5LDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

51337:Snx1
gene id: 51337:Snx1
uniprot id: A0A8C5K2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

51337:Inhbe
gene id: 51337:Inhbe
uniprot id: A0A8C5K0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

51337:Etv5
gene id: 51337:Etv5
uniprot id: A0A8C5K587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Arl17a
gene id: 51337:Arl17a
uniprot id: A0A8C5KN37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

51337:Tsc22d1
gene id: 51337:Tsc22d1
uniprot id: A0A8C5KPT9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

51337:Plac8
gene id: 51337:Plac8
uniprot id: A0A8C5KJ31
names: Similarity
messages: Belongs to the cornifelin family.

51337:Hnf1b
gene id: 51337:Hnf1b
uniprot id: A0A8C5K7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

51337:Ndst2
gene id: 51337:Ndst2
uniprot id: A0A8C5KRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Gabrd
gene id: 51337:Gabrd
uniprot id: A0A8C5L364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Vps28
gene id: 51337:Vps28
uniprot id: A0A8C5L9T6
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

51337:Adprhl1
gene id: 51337:Adprhl1
uniprot id: A0A8C5L150
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

51337:Eef1akmt2
gene id: 51337:Eef1akmt2
uniprot id: A0A8C5KA91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

51337:Tada1
gene id: 51337:Tada1
uniprot id: A0A8C5KDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TADA1 family.
messages: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

51337:Mlh1
gene id: 51337:Mlh1
uniprot id: A0A8C5LEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

51337:Calb2
gene id: 51337:Calb2
uniprot id: A0A8C5L4P3
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

51337:Prkch
gene id: 51337:Prkch
uniprot id: A0A8C5L870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

51337:LOC101603233
gene id: 51337:LOC101603233
uniprot id: A0A8C5JZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

51337:Slc52a2
gene id: 51337:Slc52a2
uniprot id: A0A8C5NX86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

51337:Sst
gene id: 51337:Sst
uniprot id: A0A8C5K8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

51337:LOC101606119
gene id: 51337:LOC101606119
uniprot id: A0A8C5L4Q3
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Adora2a
gene id: 51337:Adora2a
uniprot id: A0A8C5K4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

51337:Ppat
gene id: 51337:Ppat
uniprot id: A0A8C5L4H7
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

51337:Brf2
gene id: 51337:Brf2
uniprot id: A0A8C5KKP5
names: Similarity
messages: Belongs to the TFIIB family.

51337:Nampt
gene id: 51337:Nampt
uniprot id: A0A8C5KW81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

51337:Edn1
gene id: 51337:Edn1
uniprot id: A0A8C5L4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

51337:Slc45a2
gene id: 51337:Slc45a2
uniprot id: A0A8C5NXT1
names: Subcellular Location Annotation
messages: Membrane

51337:Aplnr
gene id: 51337:Aplnr
uniprot id: A0A8C5KGQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:C14H19orf54
gene id: 51337:C14H19orf54
uniprot id: A0A8C5JY25
names: Similarity
messages: Belongs to the UPF0692 family.

51337:LOC101608196
gene id: 51337:LOC101608196
uniprot id: A0A8C5KIQ0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

51337:Cacnb3
gene id: 51337:Cacnb3
uniprot id: A0A8C5KVU9
uniprot id: A0A8C5L2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

51337:Praf2
gene id: 51337:Praf2
uniprot id: A0A8C5P3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

51337:Crh
gene id: 51337:Crh
uniprot id: A0A8C5NXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

51337:Pabir2
gene id: 51337:Pabir2
uniprot id: A0A8C5KTJ1
names: Similarity
messages: Belongs to the FAM122 family.

51337:Abcb6
gene id: 51337:Abcb6
uniprot id: A0A8C5L571
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

51337:Bmp3
gene id: 51337:Bmp3
uniprot id: A0A8C5K3P0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

51337:LOC101597940
gene id: 51337:LOC101597940
uniprot id: A0A8C5K3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Cdc123
gene id: 51337:Cdc123
uniprot id: A0A8C5JVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

51337:Dysf
gene id: 51337:Dysf
uniprot id: A0A8C5KXL3
uniprot id: A0A8C5KZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

51337:Kcnt2
gene id: 51337:Kcnt2
uniprot id: A0A8C5K7S5
uniprot id: A0A8C5K9R0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:KEG00 p09
gene id: 51337:KEG00_p09
uniprot id: Q710T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion membrane

51337:Ranbp6
gene id: 51337:Ranbp6
uniprot id: A0A8C5K6Z1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Rnf167
gene id: 51337:Rnf167
uniprot id: A0A8C5P1Q5
names: Subcellular Location Annotation
messages: Membrane

51337:Fam102a
gene id: 51337:Fam102a
uniprot id: A0A8C5P054
names: Similarity
messages: Belongs to the FAM102 family.

51337:Draxin
gene id: 51337:Draxin
uniprot id: A0A8C5KCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

51337:Rrp7a
gene id: 51337:Rrp7a
uniprot id: A0A8C5L4U9
names: Similarity
messages: Belongs to the RRP7 family.

51337:Map3k6
gene id: 51337:Map3k6
uniprot id: A0A8C5L5P5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

51337:Csnk1g1
gene id: 51337:Csnk1g1
uniprot id: A0A8C5KBE3
uniprot id: A0A8C5KF58
uniprot id: A0A8C5KF88
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

51337:Dync1i1
gene id: 51337:Dync1i1
uniprot id: A0A8C5K3R9
names: Similarity
messages: Belongs to the dynein intermediate chain family.

51337:C5H2orf76
gene id: 51337:C5H2orf76
uniprot id: A0A8C5KMF8
names: Similarity
messages: Belongs to the UPF0538 family.

51337:Rbfox3
gene id: 51337:Rbfox3
uniprot id: A0A8C5KIC9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

51337:Pfkl
gene id: 51337:Pfkl
uniprot id: A0A8C5LB79
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Ehd1
gene id: 51337:Ehd1
uniprot id: A0A8C5L915
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

51337:Pias4
gene id: 51337:Pias4
uniprot id: A0A8C5KEY0
names: Similarity
messages: Belongs to the PIAS family.

51337:Sorcs2
gene id: 51337:Sorcs2
uniprot id: A0A8C5K2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.
messages: Membrane

51337:Thra
gene id: 51337:Thra
uniprot id: A0A8C5LGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

51337:Cdh7
gene id: 51337:Cdh7
uniprot id: A0A8C5KZB9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

51337:Tbl1xr1
gene id: 51337:Tbl1xr1
uniprot id: A0A8C5KBX9
names: Similarity
messages: Belongs to the WD repeat EBI family.

51337:LOC101599266
gene id: 51337:LOC101599266
uniprot id: A0A8C5K0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Sgms1
gene id: 51337:Sgms1
uniprot id: A0A8C5KVV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

51337:LOC101603861
gene id: 51337:LOC101603861
uniprot id: A0A8C5K817
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

51337:Htr1d
gene id: 51337:Htr1d
uniprot id: A0A8C5K503
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

51337:LOC101601054
gene id: 51337:LOC101601054
uniprot id: A0A8C5KDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

51337:Wnt10b
gene id: 51337:Wnt10b
uniprot id: A0A8C5L8H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:Gdap2
gene id: 51337:Gdap2
uniprot id: A0A8C5KJQ0
names: Similarity
messages: Belongs to the GDAP2 family.

51337:Napg
gene id: 51337:Napg
uniprot id: A0A8C5KQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

51337:Actrt2
gene id: 51337:Actrt2
uniprot id: A0A8C5K655
names: Similarity
messages: Belongs to the actin family.

51337:Gria3
gene id: 51337:Gria3
uniprot id: A0A8C5KDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Mrpl34
gene id: 51337:Mrpl34
uniprot id: A0A8C5L5F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

51337:Tubb4a
gene id: 51337:Tubb4a
uniprot id: A0A8C5JZA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Cd36
gene id: 51337:Cd36
uniprot id: A0A8C5LL05
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

51337:Gpr151
gene id: 51337:Gpr151
uniprot id: A0A8C5KMH2
names: Subcellular Location Annotation
messages: Membrane

51337:Ano3
gene id: 51337:Ano3
uniprot id: A0A8C5LCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

51337:Ap2s1
gene id: 51337:Ap2s1
uniprot id: A0A8C5JV83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

51337:Stx4
gene id: 51337:Stx4
uniprot id: A0A8C5LCS8
names: Similarity
messages: Belongs to the syntaxin family.

51337:Sec11c
gene id: 51337:Sec11c
uniprot id: A0A8C5L4W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Capza3
gene id: 51337:Capza3
uniprot id: A0A8C5NYX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

51337:Smarcd2
gene id: 51337:Smarcd2
uniprot id: A0A8C5KAB0
names: Similarity
messages: Belongs to the SMARCD family.

51337:Eml5
gene id: 51337:Eml5
uniprot id: A0A8C5LA41
names: Function
names: Subcellular Location Annotation
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
messages: cytoskeleton

51337:Foxj1
gene id: 51337:Foxj1
uniprot id: A0A8C5KFT4
names: Subcellular Location Annotation
messages: Nucleus

51337:Mmp13
gene id: 51337:Mmp13
uniprot id: A0A8C5NZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
messages: Secreted

51337:Hspa8
gene id: 51337:Hspa8
uniprot id: A0A8C5KGT2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

51337:Yars2
gene id: 51337:Yars2
uniprot id: A0A8C5JYC2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

51337:Zic3
gene id: 51337:Zic3
uniprot id: A0A8C5LE42
uniprot id: A0A8C5LFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

51337:Cdkn1a
gene id: 51337:Cdkn1a
uniprot id: A0A8C5LBK6
names: Similarity
messages: Belongs to the CDI family.

51337:Gpr176
gene id: 51337:Gpr176
uniprot id: A0A8C5LFU7
names: Subcellular Location Annotation
messages: Membrane

51337:Orc5
gene id: 51337:Orc5
uniprot id: A0A8C5LAU2
names: Subcellular Location Annotation
messages: Nucleus

51337:Nfix
gene id: 51337:Nfix
uniprot id: A0A8C5KEZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

51337:LOC101604913
gene id: 51337:LOC101604913
uniprot id: A0A8C5NVN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Ttc36
gene id: 51337:Ttc36
uniprot id: A0A8C5K8Y3
names: Similarity
messages: Belongs to the TTC36 family.

51337:Luc7l
gene id: 51337:Luc7l
uniprot id: A0A8C5NUT0
names: Similarity
messages: Belongs to the Luc7 family.

51337:Polr3b
gene id: 51337:Polr3b
uniprot id: A0A8C5LFP5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

51337:LOC101598562
gene id: 51337:LOC101598562
uniprot id: A0A8C5NZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Fitm2
gene id: 51337:Fitm2
uniprot id: A0A8C5KJN8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101608653
gene id: 51337:LOC101608653
uniprot id: A0A8C5K561
names: Similarity
messages: Belongs to the DPH3 family.

51337:Fxyd7
gene id: 51337:Fxyd7
uniprot id: A0A8C5KQU9
names: Similarity
messages: Belongs to the FXYD family.

51337:LOC101618134
gene id: 51337:LOC101618134
uniprot id: A0A8C5KVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

51337:Mat1a
gene id: 51337:Mat1a
uniprot id: A0A8C5LGA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

51337:Trpm7
gene id: 51337:Trpm7
uniprot id: A0A8C5LFB3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

51337:Trmt112
gene id: 51337:Trmt112
uniprot id: A0A8C5LBR0
names: Similarity
messages: Belongs to the TRM112 family.

51337:Timp3
gene id: 51337:Timp3
uniprot id: A0A8C5JV38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts with EFEMP1.
messages: extracellular matrix

51337:Tcea2
gene id: 51337:Tcea2
uniprot id: A0A8C5K2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

51337:Brox
gene id: 51337:Brox
uniprot id: A0A8C5K490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BROX family.
messages: Membrane

51337:Copb1
gene id: 51337:Copb1
uniprot id: A0A8C5KJU6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

51337:Tsr3
gene id: 51337:Tsr3
uniprot id: A0A8C5P1E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Plat
gene id: 51337:Plat
uniprot id: A0A8C5KZB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Rack1
gene id: 51337:Rack1
uniprot id: A0A8C5LEY9
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

51337:Pkmyt1
gene id: 51337:Pkmyt1
uniprot id: A0A8C5KBX0
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Fbp1
gene id: 51337:Fbp1
uniprot id: A0A8C5NWF6
names: Similarity
messages: Belongs to the FBPase class 1 family.

51337:LOC101597159
gene id: 51337:LOC101597159
uniprot id: A0A8C5KDJ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

51337:LOC101610487
gene id: 51337:LOC101610487
uniprot id: A0A8C5K5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

51337:Ovol2
gene id: 51337:Ovol2
uniprot id: A0A8C5KR52
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101599069
gene id: 51337:LOC101599069
uniprot id: A0A8C5LF25
names: Similarity
messages: Belongs to the peptidase C1 family.

51337:Bex3
gene id: 51337:Bex3
uniprot id: A0A8C5JZH0
names: Similarity
messages: Belongs to the BEX family.

51337:Foxa2
gene id: 51337:Foxa2
uniprot id: A0A8C5LEA8
names: Subcellular Location Annotation
messages: Nucleus

51337:Sgcg
gene id: 51337:Sgcg
uniprot id: A0A8C5NWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

51337:Pdik1l
gene id: 51337:Pdik1l
uniprot id: A0A8C5K607
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Slc25a46
gene id: 51337:Slc25a46
uniprot id: A0A8C5KQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:Btg2
gene id: 51337:Btg2
uniprot id: A0A8C5KJU4
names: Similarity
messages: Belongs to the BTG family.

51337:Gtf2f1
gene id: 51337:Gtf2f1
uniprot id: A0A8C5KYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

51337:Ca13
gene id: 51337:Ca13
uniprot id: A0A8C5KSC0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

51337:Hspa14
gene id: 51337:Hspa14
uniprot id: A0A8C5KZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

51337:Stc1
gene id: 51337:Stc1
uniprot id: A0A8C5NYH4
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

51337:Ppt1
gene id: 51337:Ppt1
uniprot id: A0A8C5KVV0
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

51337:Gpr37
gene id: 51337:Gpr37
uniprot id: A0A8C5KR12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:LOC101598065
gene id: 51337:LOC101598065
uniprot id: A0A8C5KDZ4
names: Similarity
messages: Belongs to the SMAP family.

51337:Chmp4c
gene id: 51337:Chmp4c
uniprot id: A0A8C5L653
names: Similarity
messages: Belongs to the SNF7 family.

51337:Spib
gene id: 51337:Spib
uniprot id: A0A8C5JYU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Laptm5
gene id: 51337:Laptm5
uniprot id: A0A8C5K2P0
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

51337:Mrpl15
gene id: 51337:Mrpl15
uniprot id: A0A8C5KRP1
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

51337:LOC101604849
gene id: 51337:LOC101604849
uniprot id: A0A8C5K3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

51337:Plcb2
gene id: 51337:Plcb2
uniprot id: A0A8C5K1B6
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

51337:Pde6b
gene id: 51337:Pde6b
uniprot id: A0A8C5K3U7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

51337:Cmas
gene id: 51337:Cmas
uniprot id: A0A8C5L5V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

51337:Dpf3
gene id: 51337:Dpf3
uniprot id: A0A8C5KMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

51337:Gng5
gene id: 51337:Gng5
uniprot id: A0A8C5KBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:LOC101608222
gene id: 51337:LOC101608222
uniprot id: A0A8C5KQ59
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

51337:LOC101615351
gene id: 51337:LOC101615351
uniprot id: A0A8C5L1Q4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

51337:Dda1
gene id: 51337:Dda1
uniprot id: A0A8C5LCT4
names: Similarity
messages: Belongs to the DDA1 family.

51337:Gabrr2
gene id: 51337:Gabrr2
uniprot id: A0A8C5NUF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Ccl5
gene id: 51337:Ccl5
uniprot id: A0A8C5LH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

51337:LOC101608298
gene id: 51337:LOC101608298
uniprot id: A0A8C5L953
names: Similarity
messages: Belongs to the SLBP family.

51337:Nrxn3
gene id: 51337:Nrxn3
uniprot id: A0A8C5K6Q2
uniprot id: A0A8C5K789
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:LOC101593466
gene id: 51337:LOC101593466
uniprot id: A0A8C5KJI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Mchr2
gene id: 51337:Mchr2
uniprot id: A0A8C5KZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Xylt2
gene id: 51337:Xylt2
uniprot id: A0A8C5KAJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

51337:Tmem150a
gene id: 51337:Tmem150a
uniprot id: A0A8C5NZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

51337:Rpl22l1
gene id: 51337:Rpl22l1
uniprot id: A0A8C5KQ28
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

51337:Cdh9
gene id: 51337:Cdh9
uniprot id: A0A8C5K046
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

51337:Dedd
gene id: 51337:Dedd
uniprot id: A0A8C5JWE9
names: Subcellular Location Annotation
messages: nucleolus

51337:Os9
gene id: 51337:Os9
uniprot id: A0A8C5KEU7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

51337:Apoc2
gene id: 51337:Apoc2
uniprot id: A0A8C5KWU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

51337:Ip6k1
gene id: 51337:Ip6k1
uniprot id: A0A8C5NXL2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

51337:LOC101597325
gene id: 51337:LOC101597325
uniprot id: A0A8C5KJ76
names: Similarity
messages: Belongs to the MEMO1 family.

51337:Sap30
gene id: 51337:Sap30
uniprot id: A0A8C5KXP9
names: Similarity
messages: Belongs to the SAP30 family.

51337:Ctla4
gene id: 51337:Ctla4
uniprot id: A0A8C5KHF5
uniprot id: A0A8C5KIC6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

51337:LOC101597051
gene id: 51337:LOC101597051
uniprot id: A0A8C5KKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tbx21
gene id: 51337:Tbx21
uniprot id: A0A8C5K035
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Dpp3
gene id: 51337:Dpp3
uniprot id: A0A8C5KCG5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

51337:Zbtb8os
gene id: 51337:Zbtb8os
uniprot id: A0A8C5KDI5
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

51337:Atp6v0e2
gene id: 51337:Atp6v0e2
uniprot id: A0A8C5KL43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

51337:Sstr5
gene id: 51337:Sstr5
uniprot id: A0A8C5KH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Dvl1
gene id: 51337:Dvl1
uniprot id: A0A8C5LKD1
names: Similarity
messages: Belongs to the DSH family.

51337:Cdh1
gene id: 51337:Cdh1
uniprot id: A0A8C5LI66
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
messages: Membrane
messages: trans-Golgi network

51337:Grk6
gene id: 51337:Grk6
uniprot id: A0A8C5K8D8
uniprot id: A0A8C5KBZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

51337:Sec61a1
gene id: 51337:Sec61a1
uniprot id: A0A8C5JU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Ap2a1
gene id: 51337:Ap2a1
uniprot id: A0A8C5LK79
uniprot id: A0A8C5LKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

51337:Tbx5
gene id: 51337:Tbx5
uniprot id: A0A8C5KZJ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

51337:Alpl
gene id: 51337:Alpl
uniprot id: A0A8C5KBF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

51337:Slco1c1
gene id: 51337:Slco1c1
uniprot id: A0A8C5KSG9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Tfap2a
gene id: 51337:Tfap2a
uniprot id: A0A8C5KPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

51337:Nrxn2
gene id: 51337:Nrxn2
uniprot id: A0A8C5P1K5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Sucla2
gene id: 51337:Sucla2
uniprot id: A0A8C5K606
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

51337:Cemip2
gene id: 51337:Cemip2
uniprot id: A0A8C5KWF8
names: Similarity
messages: Belongs to the CEMIP family.

51337:Slc25a25
gene id: 51337:Slc25a25
uniprot id: A0A8C5KZL7
uniprot id: A0A8C5L376
uniprot id: A0A8C5L4E4
uniprot id: A0A8C5P274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Prpsap1
gene id: 51337:Prpsap1
uniprot id: A0A8C5KI96
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

51337:Ifrd2
gene id: 51337:Ifrd2
uniprot id: A0A8C5KQA4
names: Similarity
messages: Belongs to the IFRD family.

51337:Rbm22
gene id: 51337:Rbm22
uniprot id: A0A8C5K467
names: Similarity
messages: Belongs to the SLT11 family.

51337:Cebpz
gene id: 51337:Cebpz
uniprot id: A0A8C5NX47
names: Similarity
messages: Belongs to the CBF/MAK21 family.

51337:Cdh18
gene id: 51337:Cdh18
uniprot id: A0A8C5KUS0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

51337:LOC101609989
gene id: 51337:LOC101609989
uniprot id: A0A8C5NYP2
names: Similarity
messages: Belongs to the peptidase A1 family.

51337:Amacr
gene id: 51337:Amacr
uniprot id: A0A8C5NXS0
names: Similarity
messages: Belongs to the CoA-transferase III family.

51337:Cfap36
gene id: 51337:Cfap36
uniprot id: A0A8C5L222
names: Similarity
messages: Belongs to the CFAP36 family.

51337:Foxo1
gene id: 51337:Foxo1
uniprot id: A0A8C5KCB3
names: Subcellular Location Annotation
messages: Nucleus

51337:Uba5
gene id: 51337:Uba5
uniprot id: A0A8C5LHF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus

51337:Syngr1
gene id: 51337:Syngr1
uniprot id: A0A8C5KMA3
uniprot id: A0A8C5NZL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

51337:Grm3
gene id: 51337:Grm3
uniprot id: A0A8C5P2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

51337:Polr2f
gene id: 51337:Polr2f
uniprot id: A0A8C5K1U6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

51337:Rhbdl1
gene id: 51337:Rhbdl1
uniprot id: A0A8C5LAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

51337:Pgk2
gene id: 51337:Pgk2
uniprot id: A0A8C5JYE9
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

51337:Pdss2
gene id: 51337:Pdss2
uniprot id: A0A8C5L4Y3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

51337:LOC101617366
gene id: 51337:LOC101617366
uniprot id: A0A8C5LDP1
names: Similarity
messages: Belongs to the PRORSD1 family.

51337:Gpc4
gene id: 51337:Gpc4
uniprot id: A0A8C5KGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

51337:Plac8l1
gene id: 51337:Plac8l1
uniprot id: A0A8C5LGK8
names: Similarity
messages: Belongs to the cornifelin family.

51337:Cops9
gene id: 51337:Cops9
uniprot id: A0A8C5K5X5
names: Similarity
messages: Belongs to the CSN9 family.

51337:Psmd11
gene id: 51337:Psmd11
uniprot id: A0A8C5KQG8
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

51337:Hmga1
gene id: 51337:Hmga1
uniprot id: A0A8C5L422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

51337:Ric8b
gene id: 51337:Ric8b
uniprot id: A0A8C5L1K3
uniprot id: A0A8C5P2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

51337:Asz1
gene id: 51337:Asz1
uniprot id: A0A8C5P4I1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

51337:Tomm40l
gene id: 51337:Tomm40l
uniprot id: A0A8C5K7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:Slc27a1
gene id: 51337:Slc27a1
uniprot id: A0A8C5JZX8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

51337:Pebp1
gene id: 51337:Pebp1
uniprot id: A0A8C5KX35
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

51337:Eme2
gene id: 51337:Eme2
uniprot id: A0A8C5LBT6
names: Similarity
messages: Belongs to the EME1/MMS4 family.

51337:Slco4a1
gene id: 51337:Slco4a1
uniprot id: A0A8C5L373
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Bzw2
gene id: 51337:Bzw2
uniprot id: A0A8C5KQ69
names: Similarity
messages: Belongs to the BZW family.

51337:Batf
gene id: 51337:Batf
uniprot id: A0A8C5NVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

51337:Jrkl
gene id: 51337:Jrkl
uniprot id: A0A8C5K0U5
names: Subcellular Location Annotation
messages: Nucleus

51337:Fzd6
gene id: 51337:Fzd6
uniprot id: A0A8C5NY42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Smad5
gene id: 51337:Smad5
uniprot id: A0A8C5KZH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

51337:Dlk2
gene id: 51337:Dlk2
uniprot id: A0A8C5KF08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Pter
gene id: 51337:Pter
uniprot id: A0A8C5P407
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:LOC101615764
gene id: 51337:LOC101615764
uniprot id: A0A8C5KCH1
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Lmnb1
gene id: 51337:Lmnb1
uniprot id: A0A8C5KPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

51337:Snu13
gene id: 51337:Snu13
uniprot id: A0A8C5KLQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

51337:Lrp6
gene id: 51337:Lrp6
uniprot id: A0A8C5KK85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Eml6
gene id: 51337:Eml6
uniprot id: A0A8C5JYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
messages: cytoskeleton

51337:Coro1a
gene id: 51337:Coro1a
uniprot id: A0A8C5NZF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

51337:Grm1
gene id: 51337:Grm1
uniprot id: A0A8C5L1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

51337:Cpb2
gene id: 51337:Cpb2
uniprot id: A0A8C5LA02
names: Similarity
messages: Belongs to the peptidase M14 family.

51337:Abhd12
gene id: 51337:Abhd12
uniprot id: A0A8C5LC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Ing2
gene id: 51337:Ing2
uniprot id: A0A8C5P4I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

51337:Osgepl1
gene id: 51337:Osgepl1
uniprot id: A0A8C5P0L6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

51337:Kcns2
gene id: 51337:Kcns2
uniprot id: A0A8C5L933
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Tmem165
gene id: 51337:Tmem165
uniprot id: A0A8C5K4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

51337:Ergic1
gene id: 51337:Ergic1
uniprot id: A0A8C5K1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

51337:Utp25
gene id: 51337:Utp25
uniprot id: A0A8C5LHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

51337:Tas1r2
gene id: 51337:Tas1r2
uniprot id: A0A8C5L539
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Pacsin2
gene id: 51337:Pacsin2
uniprot id: A0A8C5LAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

51337:B9d1
gene id: 51337:B9d1
uniprot id: A0A8C5LI99
names: Subcellular Location Annotation
messages: cilium basal body

51337:Clrn1
gene id: 51337:Clrn1
uniprot id: A0A8C5K076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

51337:Pdcl3
gene id: 51337:Pdcl3
uniprot id: A0A8C5KAE6
names: Similarity
messages: Belongs to the phosducin family.

51337:Xpo5
gene id: 51337:Xpo5
uniprot id: A0A8C5NW13
names: Subcellular Location Annotation
messages: Cytoplasm

51337:LOC101614943
gene id: 51337:LOC101614943
uniprot id: A0A8C5KN95
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

51337:Pgam2
gene id: 51337:Pgam2
uniprot id: A0A8C5K2P1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

51337:Mgat5b
gene id: 51337:Mgat5b
uniprot id: A0A8C5KFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Polg2
gene id: 51337:Polg2
uniprot id: A0A8C5KZS1
names: Subcellular Location Annotation
messages: Mitochondrion

51337:Gjb6
gene id: 51337:Gjb6
uniprot id: A0A8C5KGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Cltb
gene id: 51337:Cltb
uniprot id: A0A8C5LAB3
uniprot id: A0A8C5LAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

51337:Pdx1
gene id: 51337:Pdx1
uniprot id: A0A8C5L110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:LOC101609251
gene id: 51337:LOC101609251
uniprot id: A0A8C5L6F7
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Mvk
gene id: 51337:Mvk
uniprot id: A0A8C5P5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

51337:Atp5f1c
gene id: 51337:Atp5f1c
uniprot id: A0A8C5LCU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

51337:Orc4
gene id: 51337:Orc4
uniprot id: A0A8C5NWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

51337:Metap1
gene id: 51337:Metap1
uniprot id: A0A8C5K7I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

51337:Rad23a
gene id: 51337:Rad23a
uniprot id: A0A8C5JWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

51337:Scgn
gene id: 51337:Scgn
uniprot id: A0A8C5NZC8
names: Subcellular Location Annotation
messages: secretory vesicle membrane

51337:Tmem59
gene id: 51337:Tmem59
uniprot id: A0A8C5K565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Fzd1
gene id: 51337:Fzd1
uniprot id: A0A8C5NXL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Vps54
gene id: 51337:Vps54
uniprot id: A0A8C5NY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

51337:Fuca1
gene id: 51337:Fuca1
uniprot id: A0A8C5KGW7
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

51337:Atrn
gene id: 51337:Atrn
uniprot id: A0A8C5NYX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Ace2
gene id: 51337:Ace2
uniprot id: A0A8C5JWR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

51337:Ddx55
gene id: 51337:Ddx55
uniprot id: A0A8C5KJD6
names: Similarity
messages: Belongs to the DEAD box helicase family.

51337:Adgrb2
gene id: 51337:Adgrb2
uniprot id: A0A8C5KSI2
uniprot id: A0A8C5KXB3
names: Subcellular Location Annotation
messages: Membrane

51337:Chrng
gene id: 51337:Chrng
uniprot id: A0A8C5KR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Glyctk
gene id: 51337:Glyctk
uniprot id: A0A8C5K9Y3
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

51337:LOC101612603
gene id: 51337:LOC101612603
uniprot id: A0A8C5KEM9
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

51337:Stoml3
gene id: 51337:Stoml3
uniprot id: A0A8C5KP77
names: Similarity
messages: Belongs to the band 7/mec-2 family.

51337:Mrps33
gene id: 51337:Mrps33
uniprot id: A0A8C5KYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

51337:Hao2
gene id: 51337:Hao2
uniprot id: A0A8C5P3Z8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

51337:Pld3
gene id: 51337:Pld3
uniprot id: A0A8C5KUM1
names: Similarity
messages: Belongs to the phospholipase D family.

51337:Slc39a8
gene id: 51337:Slc39a8
uniprot id: A0A8C5K5L0
names: Subcellular Location Annotation
messages: Membrane

51337:Mrpl50
gene id: 51337:Mrpl50
uniprot id: A0A8C5KPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

51337:Capzb
gene id: 51337:Capzb
uniprot id: A0A8C5LAP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton
messages: sarcomere

51337:Gsx2
gene id: 51337:Gsx2
uniprot id: A0A8C5NX33
names: Subcellular Location Annotation
messages: Nucleus

51337:Rragb
gene id: 51337:Rragb
uniprot id: A0A8C5L9I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

51337:Nup35
gene id: 51337:Nup35
uniprot id: A0A8C5P0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

51337:Actn2
gene id: 51337:Actn2
uniprot id: A0A8C5P0N6
names: Similarity
messages: Belongs to the alpha-actinin family.

51337:Ppp1r2
gene id: 51337:Ppp1r2
uniprot id: A0A8C5K060
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

51337:Cyyr1
gene id: 51337:Cyyr1
uniprot id: A0A8C5JUE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

51337:LOC101593557
gene id: 51337:LOC101593557
uniprot id: A0A8C5KMU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Myorg
gene id: 51337:Myorg
uniprot id: A0A8C5K0R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

51337:Pigk
gene id: 51337:Pigk
uniprot id: A0A8C5LK08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Endoplasmic reticulum membrane
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

51337:Pgm3
gene id: 51337:Pgm3
uniprot id: A0A8C5KIA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

51337:Mknk2
gene id: 51337:Mknk2
uniprot id: A0A8C5KTF3
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Nop53
gene id: 51337:Nop53
uniprot id: A0A8C5K4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

51337:Pdk1
gene id: 51337:Pdk1
uniprot id: A0A8C5L732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

51337:Bcl9
gene id: 51337:Bcl9
uniprot id: A0A8C5L7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

51337:Romo1
gene id: 51337:Romo1
uniprot id: A0A8C5KGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

51337:Fbxl5
gene id: 51337:Fbxl5
uniprot id: A0A8C5JYA8
names: Subcellular Location Annotation
messages: perinuclear region

51337:Eif3m
gene id: 51337:Eif3m
uniprot id: A0A8C5KCI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

51337:LOC101600883
gene id: 51337:LOC101600883
uniprot id: A0A8C5KDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Hbegf
gene id: 51337:Hbegf
uniprot id: A0A8C5KCD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Myb
gene id: 51337:Myb
uniprot id: A0A8C5P5H9
names: Subcellular Location Annotation
messages: Nucleus

51337:Ccm2
gene id: 51337:Ccm2
uniprot id: A0A8C5P357
names: Similarity
messages: Belongs to the CCM2 family.

51337:Carnmt1
gene id: 51337:Carnmt1
uniprot id: A0A8C5KJ84
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

51337:Tle5
gene id: 51337:Tle5
uniprot id: A0A8C5KN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

51337:Med11
gene id: 51337:Med11
uniprot id: A0A8C5KZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

51337:Ube2r2
gene id: 51337:Ube2r2
uniprot id: A0A8C5LIQ1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Tmcc3
gene id: 51337:Tmcc3
uniprot id: A0A8C5KRF1
names: Similarity
messages: Belongs to the TEX28 family.

51337:Comtd1
gene id: 51337:Comtd1
uniprot id: A0A8C5P5K1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

51337:Ppil4
gene id: 51337:Ppil4
uniprot id: A0A8C5KZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

51337:Arsb
gene id: 51337:Arsb
uniprot id: A0A8C5NXA3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Fam120b
gene id: 51337:Fam120b
uniprot id: A0A8C5KXH0
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

51337:Lhb
gene id: 51337:Lhb
uniprot id: A0A8C5K7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

51337:Tmod1
gene id: 51337:Tmod1
uniprot id: A0A8C5K305
names: Subcellular Location Annotation
messages: cytoskeleton

51337:Ext2
gene id: 51337:Ext2
uniprot id: A0A8C5K1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Tsc22d3
gene id: 51337:Tsc22d3
uniprot id: A0A8C5K0S9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

51337:Ccdc85a
gene id: 51337:Ccdc85a
uniprot id: A0A8C5L8Q5
uniprot id: A0A8C5L9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

51337:Rexo2
gene id: 51337:Rexo2
uniprot id: A0A8C5KGX4
names: Similarity
messages: Belongs to the oligoribonuclease family.

51337:Unc5a
gene id: 51337:Unc5a
uniprot id: A0A8C5K4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

51337:Zw10
gene id: 51337:Zw10
uniprot id: A0A8C5KNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

51337:Gabrr3
gene id: 51337:Gabrr3
uniprot id: A0A8C5L186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

51337:Tmem242
gene id: 51337:Tmem242
uniprot id: A0A8C5KBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

51337:Tomm5
gene id: 51337:Tomm5
uniprot id: A0A8C5KCF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:Prkcz
gene id: 51337:Prkcz
uniprot id: A0A8C5KZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Endosome

51337:Emc6
gene id: 51337:Emc6
uniprot id: A0A8C5KGI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Rap1gds1
gene id: 51337:Rap1gds1
uniprot id: A0A8C5KX50
uniprot id: A0A8C5KZG0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

51337:Vps25
gene id: 51337:Vps25
uniprot id: A0A8C5JZF6
names: Similarity
messages: Belongs to the VPS25 family.

51337:Npr2
gene id: 51337:Npr2
uniprot id: A0A8C5LBG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

51337:LOC101601000
gene id: 51337:LOC101601000
uniprot id: A0A8C5K686
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

51337:Mmp17
gene id: 51337:Mmp17
uniprot id: A0A8C5K9I8
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:Cacna1g
gene id: 51337:Cacna1g
uniprot id: A0A8C5K6I1
uniprot id: A0A8C5K8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

51337:Cfap298
gene id: 51337:Cfap298
uniprot id: A0A8C5KVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

51337:Stoml1
gene id: 51337:Stoml1
uniprot id: A0A8C5KJI4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

51337:C2H8orf82
gene id: 51337:C2H8orf82
uniprot id: A0A8C5L0T2
names: Similarity
messages: Belongs to the UPF0598 family.

51337:Ric8a
gene id: 51337:Ric8a
uniprot id: A0A8C5P0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

51337:Il1rn
gene id: 51337:Il1rn
uniprot id: A0A8C5KHN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

51337:Rpl12
gene id: 51337:Rpl12
uniprot id: A0A8C5KD43
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

51337:Epyc
gene id: 51337:Epyc
uniprot id: A0A8C5KLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: extracellular matrix

51337:Tas1r1
gene id: 51337:Tas1r1
uniprot id: A0A8C5KLP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Fmo3
gene id: 51337:Fmo3
uniprot id: A0A8C5L6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
messages: Microsome membrane

51337:Rab27b
gene id: 51337:Rab27b
uniprot id: A0A8C5L5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

51337:Ola1
gene id: 51337:Ola1
uniprot id: A0A8C5LHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

51337:LOC101606376
gene id: 51337:LOC101606376
uniprot id: A0A8C5L8S3
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

51337:LOC101611315
gene id: 51337:LOC101611315
uniprot id: A0A8C5JZU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with IL8. Interacts with GNAI2.
messages: Membrane

51337:Pdia4
gene id: 51337:Pdia4
uniprot id: A0A8C5NZH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Part of a large chaperone multiprotein complex.

51337:C1H1orf74
gene id: 51337:C1H1orf74
uniprot id: A0A8C5K760
names: Similarity
messages: Belongs to the UPF0739 family.

51337:Derl2
gene id: 51337:Derl2
uniprot id: A0A8C5KRW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:LOC101617318
gene id: 51337:LOC101617318
uniprot id: A0A8C5K9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

51337:Sirt3
gene id: 51337:Sirt3
uniprot id: A0A8C5LB73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

51337:Galr1
gene id: 51337:Galr1
uniprot id: A0A8C5KJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Igf2bp3
gene id: 51337:Igf2bp3
uniprot id: A0A8C5NXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule

51337:C11H16orf91
gene id: 51337:C11H16orf91
uniprot id: A0A8C5JZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCSMST1 family.
messages: Membrane

51337:LOC101611467
gene id: 51337:LOC101611467
uniprot id: A0A8C5K904
names: Similarity
messages: Belongs to the DPH3 family.

51337:Timm44
gene id: 51337:Timm44
uniprot id: A0A8C5K4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

51337:LOC101599999
gene id: 51337:LOC101599999
uniprot id: A0A8C5KIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Il19
gene id: 51337:Il19
uniprot id: A0A8C5JZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

51337:Ddah1
gene id: 51337:Ddah1
uniprot id: A0A8C5KSI1
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

51337:KEG00 p08
gene id: 51337:KEG00_p08
uniprot id: Q710T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

51337:Atp6v1b2
gene id: 51337:Atp6v1b2
uniprot id: A0A8C5L8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

51337:Rnf31
gene id: 51337:Rnf31
uniprot id: A0A8C5P151
names: Similarity
messages: Belongs to the RBR family.

51337:Phactr3
gene id: 51337:Phactr3
uniprot id: A0A8C5LEH7
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

51337:Ogg1
gene id: 51337:Ogg1
uniprot id: A0A8C5K2M8
names: Function
names: Similarity
messages: Belongs to the type-1 OGG1 family.
messages: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

51337:Smc1b
gene id: 51337:Smc1b
uniprot id: A0A8C5LET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

51337:Psmg2
gene id: 51337:Psmg2
uniprot id: A0A8C5LA90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

51337:Mrpl3
gene id: 51337:Mrpl3
uniprot id: A0A8C5K209
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

51337:Mc4r
gene id: 51337:Mc4r
uniprot id: A0A8C5K0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

51337:Rogdi
gene id: 51337:Rogdi
uniprot id: A0A8C5KTZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: synaptic vesicle

51337:Serpina11
gene id: 51337:Serpina11
uniprot id: A0A8C5K8J9
names: Similarity
messages: Belongs to the serpin family.

51337:Acadvl
gene id: 51337:Acadvl
uniprot id: A0A8C5KBQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

51337:Rabac1
gene id: 51337:Rabac1
uniprot id: A0A8C5JW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

51337:Parp1
gene id: 51337:Parp1
uniprot id: A0A8C5LGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Interacts (when auto-poly-ADP-ribosylated) with AIFM1.
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.
messages: This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

51337:Crot
gene id: 51337:Crot
uniprot id: A0A8C5K9R6
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

51337:Kif3c
gene id: 51337:Kif3c
uniprot id: A0A8C5KX98
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:LOC101600107
gene id: 51337:LOC101600107
uniprot id: A0A8C5NXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Hoxc8
gene id: 51337:Hoxc8
uniprot id: A0A8C5KCP3
names: Subcellular Location Annotation
messages: Nucleus

51337:Hacd3
gene id: 51337:Hacd3
uniprot id: A0A8C5KUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Sugp1
gene id: 51337:Sugp1
uniprot id: A0A8C5KG74
names: Subcellular Location Annotation
messages: Nucleus

51337:Gdi1
gene id: 51337:Gdi1
uniprot id: A0A8C5K873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

51337:Apeh
gene id: 51337:Apeh
uniprot id: A0A8C5L5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

51337:Tfb2m
gene id: 51337:Tfb2m
uniprot id: A0A8C5P2R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

51337:LOC101601326
gene id: 51337:LOC101601326
uniprot id: A0A8C5KM35
names: Similarity
messages: Belongs to the arrestin family.

51337:Ppfibp2
gene id: 51337:Ppfibp2
uniprot id: A0A8C5P0R1
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

51337:Prickle3
gene id: 51337:Prickle3
uniprot id: A0A8C5JZK8
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

51337:Strip1
gene id: 51337:Strip1
uniprot id: A0A8C5KE61
names: Similarity
messages: Belongs to the STRIP family.

51337:LOC101594249
gene id: 51337:LOC101594249
uniprot id: A0A8C5KRI1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

51337:Psmb11
gene id: 51337:Psmb11
uniprot id: A0A8C5JXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

51337:Naa35
gene id: 51337:Naa35
uniprot id: A0A8C5KRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

51337:Tmem43
gene id: 51337:Tmem43
uniprot id: A0A8C5KUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

51337:Adm
gene id: 51337:Adm
uniprot id: A0A8C5LLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

51337:Gfm1
gene id: 51337:Gfm1
uniprot id: A0A8C5KR70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

51337:Mecp2
gene id: 51337:Mecp2
uniprot id: A0A8C5LDB3
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

51337:Prkca
gene id: 51337:Prkca
uniprot id: A0A8C5P335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

51337:Atp6v1e1
gene id: 51337:Atp6v1e1
uniprot id: A0A8C5KE80
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

51337:Trappc4
gene id: 51337:Trappc4
uniprot id: A0A8C5P1T0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

51337:Adcy8
gene id: 51337:Adcy8
uniprot id: A0A8C5L3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

51337:Amdhd2
gene id: 51337:Amdhd2
uniprot id: A0A8C5KZG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

51337:Hoxa7
gene id: 51337:Hoxa7
uniprot id: A0A8C5JW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Cept1
gene id: 51337:Cept1
uniprot id: A0A8C5LAE5
uniprot id: A0A8C5LIC2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

51337:Dclre1c
gene id: 51337:Dclre1c
uniprot id: A0A8C5JVR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

51337:Mtfp1
gene id: 51337:Mtfp1
uniprot id: A0A8C5JYC3
names: Similarity
messages: Belongs to the MTFP1 family.

51337:Gria1
gene id: 51337:Gria1
uniprot id: A0A8C5K9D8
uniprot id: A0A8C5KBV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Metap2
gene id: 51337:Metap2
uniprot id: A0A8C5KXK5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

51337:LOC101595136
gene id: 51337:LOC101595136
uniprot id: A0A8C5P1S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

51337:Lim2
gene id: 51337:Lim2
uniprot id: A0A8C5KBH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

51337:Zic1
gene id: 51337:Zic1
uniprot id: A0A8C5KH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

51337:Tmem47
gene id: 51337:Tmem47
uniprot id: A0A8C5KXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

51337:Lgi1
gene id: 51337:Lgi1
uniprot id: A0A8C5KV95
names: Subcellular Location Annotation
messages: Secreted

51337:Ppcs
gene id: 51337:Ppcs
uniprot id: A0A8C5K6T8
names: Similarity
messages: Belongs to the PPC synthetase family.

51337:Dyrk2
gene id: 51337:Dyrk2
uniprot id: A0A8C5KXU2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

51337:Men1
gene id: 51337:Men1
uniprot id: A0A8C5L5J9
names: Subcellular Location Annotation
messages: Nucleus

51337:LOC101610963
gene id: 51337:LOC101610963
uniprot id: A0A8C5K8M8
uniprot id: A0A8C5KD30
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Mtmr9
gene id: 51337:Mtmr9
uniprot id: A0A8C5NWX3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

51337:Cpne9
gene id: 51337:Cpne9
uniprot id: A0A8C5L4Q6
names: Similarity
messages: Belongs to the copine family.

51337:Prpf4b
gene id: 51337:Prpf4b
uniprot id: A0A8C5K908
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

51337:Tef
gene id: 51337:Tef
uniprot id: A0A8C5K4B7
uniprot id: A0A8C5K8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

51337:Mrpl28
gene id: 51337:Mrpl28
uniprot id: A0A8C5K2L4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

51337:Fzd7
gene id: 51337:Fzd7
uniprot id: A0A8C5K9H4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Aida
gene id: 51337:Aida
uniprot id: A0A8C5P5V8
names: Similarity
messages: Belongs to the AIDA family.

51337:Cd93
gene id: 51337:Cd93
uniprot id: A0A8C5K2T8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Cdkn3
gene id: 51337:Cdkn3
uniprot id: A0A8C5KNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

51337:LOC101608985
gene id: 51337:LOC101608985
uniprot id: A0A8C5KBZ1
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

51337:Asb17
gene id: 51337:Asb17
uniprot id: A0A8C5K1P0
names: Function
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

51337:Ap3b2
gene id: 51337:Ap3b2
uniprot id: A0A8C5NV61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

51337:Serpini1
gene id: 51337:Serpini1
uniprot id: A0A8C5KIU2
names: Similarity
messages: Belongs to the serpin family.

51337:Slc18a3
gene id: 51337:Slc18a3
uniprot id: A0A8C5KF74
names: Subcellular Location Annotation
messages: Membrane

51337:Prps1
gene id: 51337:Prps1
uniprot id: A0A8C5NXX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

51337:Gpr171
gene id: 51337:Gpr171
uniprot id: A0A8C5K566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:LOC101601195
gene id: 51337:LOC101601195
uniprot id: A0A8C5JZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane
messages: synaptosome

51337:Mpdu1
gene id: 51337:Mpdu1
uniprot id: A0A8C5L7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

51337:Oprl1
gene id: 51337:Oprl1
uniprot id: A0A8C5K7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

51337:Sbk3
gene id: 51337:Sbk3
uniprot id: A0A8C5K215
names: Similarity
messages: Belongs to the protein kinase superfamily.

51337:Elovl6
gene id: 51337:Elovl6
uniprot id: A0A8C5NZK5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

51337:Chmp4b
gene id: 51337:Chmp4b
uniprot id: A0A8C5KGC9
names: Similarity
messages: Belongs to the SNF7 family.

51337:Nkx6-1
gene id: 51337:Nkx6-1
uniprot id: A0A8C5LDV8
names: Subcellular Location Annotation
messages: Nucleus

51337:Tppp2
gene id: 51337:Tppp2
uniprot id: A0A8C5P2J1
names: Similarity
messages: Belongs to the TPPP family.

51337:Fzd5
gene id: 51337:Fzd5
uniprot id: A0A8C5K1Z1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Rab39b
gene id: 51337:Rab39b
uniprot id: A0A8C5KVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

51337:Ccnjl
gene id: 51337:Ccnjl
uniprot id: A0A8C5KPW3
names: Similarity
messages: Belongs to the cyclin family.

51337:Gba2
gene id: 51337:Gba2
uniprot id: A0A8C5LC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

51337:Glra2
gene id: 51337:Glra2
uniprot id: A0A8C5KFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

51337:Pomc
gene id: 51337:Pomc
uniprot id: A0A8C5JXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

51337:Comt
gene id: 51337:Comt
uniprot id: A0A8C5KW31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
messages: Cell membrane

51337:LOC101617310
gene id: 51337:LOC101617310
uniprot id: A0A8C5K4D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

51337:Tmem45b
gene id: 51337:Tmem45b
uniprot id: A0A8C5L7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

51337:Cln3
gene id: 51337:Cln3
uniprot id: A0A8C5P219
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

51337:Gcc1
gene id: 51337:Gcc1
uniprot id: A0A8C5NUP1
names: Subcellular Location Annotation
messages: Membrane

51337:Mfsd5
gene id: 51337:Mfsd5
uniprot id: A0A8C5L4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

51337:Clca1
gene id: 51337:Clca1
uniprot id: A0A8C5NVW2
names: Similarity
messages: Belongs to the CLCR family.

51337:Agpat4
gene id: 51337:Agpat4
uniprot id: A0A8C5P5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

51337:Clps
gene id: 51337:Clps
uniprot id: A0A8C5P1S4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

51337:Ube2l3
gene id: 51337:Ube2l3
uniprot id: A0A8C5K3L4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Naa40
gene id: 51337:Naa40
uniprot id: A0A8C5KAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

51337:Upf3b
gene id: 51337:Upf3b
uniprot id: A0A8C5JW24
names: Similarity
messages: Belongs to the RENT3 family.

51337:Plpp1
gene id: 51337:Plpp1
uniprot id: A0A8C5L7W2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

51337:Hgh1
gene id: 51337:Hgh1
uniprot id: A0A8C5LFT4
names: Similarity
messages: Belongs to the HGH1 family.

51337:Ahsa1
gene id: 51337:Ahsa1
uniprot id: A0A8C5L1L2
names: Similarity
messages: Belongs to the AHA1 family.

51337:Ppp1r14d
gene id: 51337:Ppp1r14d
uniprot id: A0A8C5KCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

51337:Polr2a
gene id: 51337:Polr2a
uniprot id: A0A8C5KJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

51337:Lum
gene id: 51337:Lum
uniprot id: A0A8C5KY68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

51337:Litaf
gene id: 51337:Litaf
uniprot id: A0A8C5KGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

51337:Fabp6
gene id: 51337:Fabp6
uniprot id: A0A8C5KG08
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

51337:Gngt1
gene id: 51337:Gngt1
uniprot id: A0A8C5LLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

51337:LOC101613124
gene id: 51337:LOC101613124
uniprot id: A0A8C5LFE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

51337:Gjb1
gene id: 51337:Gjb1
uniprot id: A0A8C5KM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

51337:Jpt2
gene id: 51337:Jpt2
uniprot id: A0A8C5P4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

51337:Ppil3
gene id: 51337:Ppil3
uniprot id: A0A8C5KG45
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

51337:Echs1
gene id: 51337:Echs1
uniprot id: A0A8C5KY91
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

51337:Kcnj5
gene id: 51337:Kcnj5
uniprot id: A0A8C5KS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

51337:Rab33a
gene id: 51337:Rab33a
uniprot id: A0A8C5K1Z0
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

51337:Lyrm1
gene id: 51337:Lyrm1
uniprot id: A0A8C5JZ91
names: Similarity
messages: Belongs to the complex I LYR family.

51337:Gtpbp1
gene id: 51337:Gtpbp1
uniprot id: A0A8C5KBZ6
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

51337:Cldn22
gene id: 51337:Cldn22
uniprot id: A0A8C5K4T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Syngr4
gene id: 51337:Syngr4
uniprot id: A0A8C5K5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

51337:Stard6
gene id: 51337:Stard6
uniprot id: A0A8C5P5R0
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

51337:Rpl3
gene id: 51337:Rpl3
uniprot id: A0A8C5KQB9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

51337:Slc7a6os
gene id: 51337:Slc7a6os
uniprot id: A0A8C5KWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

51337:Ndufs5
gene id: 51337:Ndufs5
uniprot id: A0A8C5NVA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Arhgdig
gene id: 51337:Arhgdig
uniprot id: A0A8C5P5G1
names: Similarity
messages: Belongs to the Rho GDI family.

51337:Sqle
gene id: 51337:Sqle
uniprot id: A0A8C5L1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

51337:Acot8
gene id: 51337:Acot8
uniprot id: A0A8C5KL18
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

51337:Sidt2
gene id: 51337:Sidt2
uniprot id: A0A8C5P0V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

51337:Snapc3
gene id: 51337:Snapc3
uniprot id: A0A8C5L007
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

51337:Copb2
gene id: 51337:Copb2
uniprot id: A0A8C5L9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

51337:LOC101610722
gene id: 51337:LOC101610722
uniprot id: A0A8C5JW47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP18 family.
messages: Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit mRNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function.
messages: Cytoplasm
messages: Nucleus speckle

51337:Ap1b1
gene id: 51337:Ap1b1
uniprot id: A0A8C5K391
uniprot id: A0A8C5NUX9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

51337:Cln8
gene id: 51337:Cln8
uniprot id: A0A8C5KRR9
names: Subcellular Location Annotation
messages: Membrane

51337:Bpifc
gene id: 51337:Bpifc
uniprot id: A0A8C5K157
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

51337:Slc6a8
gene id: 51337:Slc6a8
uniprot id: A0A8C5LE02
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
messages: Cell membrane
messages: Membrane

51337:Hoga1
gene id: 51337:Hoga1
uniprot id: A0A8C5KFD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

51337:Popdc2
gene id: 51337:Popdc2
uniprot id: A0A8C5KL59
names: Similarity
messages: Belongs to the popeye family.

51337:Polr2h
gene id: 51337:Polr2h
uniprot id: A0A8C5KMM5
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

51337:Cd40lg
gene id: 51337:Cd40lg
uniprot id: A0A8C5LDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

51337:Rasgrp1
gene id: 51337:Rasgrp1
uniprot id: A0A8C5L1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RASGRP family.
messages: cytosol

51337:Ptgs1
gene id: 51337:Ptgs1
uniprot id: A0A8C5L3A3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Rusf1
gene id: 51337:Rusf1
uniprot id: A0A8C5L5D3
names: Similarity
messages: Belongs to the RUS1 family.

51337:LOC101616776
gene id: 51337:LOC101616776
uniprot id: A0A8C5L298
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

51337:Ddr2
gene id: 51337:Ddr2
uniprot id: A0A8C5K8R0
names: Subcellular Location Annotation
messages: Membrane

51337:En2
gene id: 51337:En2
uniprot id: A0A8C5KVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

51337:Gnpda2
gene id: 51337:Gnpda2
uniprot id: A0A8C5P1B7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

51337:Paqr8
gene id: 51337:Paqr8
uniprot id: A0A8C5K292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

51337:Arf1
gene id: 51337:Arf1
uniprot id: A0A8C5L3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

51337:Mrpl17
gene id: 51337:Mrpl17
uniprot id: A0A8C5LEW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

51337:Acox2
gene id: 51337:Acox2
uniprot id: A0A8C5LMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

51337:Casp2
gene id: 51337:Casp2
uniprot id: A0A8C5K2Z7
names: Similarity
messages: Belongs to the peptidase C14A family.

51337:Ccno
gene id: 51337:Ccno
uniprot id: A0A8C5L4R8
names: Similarity
messages: Belongs to the cyclin family.

51337:Timm17b
gene id: 51337:Timm17b
uniprot id: A0A8C5P361
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Serpine3
gene id: 51337:Serpine3
uniprot id: A0A8C5KXB1
names: Similarity
messages: Belongs to the serpin family.

51337:Cd79b
gene id: 51337:Cd79b
uniprot id: A0A8C5K413
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Npb
gene id: 51337:Npb
uniprot id: A0A8C5K9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

51337:Rell1
gene id: 51337:Rell1
uniprot id: A0A8C5KR19
names: Similarity
messages: Belongs to the RELT family.

51337:Acer2
gene id: 51337:Acer2
uniprot id: A0A8C5P3U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Dao
gene id: 51337:Dao
uniprot id: A0A8C5L3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

51337:Tmem170a
gene id: 51337:Tmem170a
uniprot id: A0A8C5LHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

51337:Kcnn2
gene id: 51337:Kcnn2
uniprot id: A0A8C5KLQ2
names: Subcellular Location Annotation
messages: Membrane

51337:Pfn3
gene id: 51337:Pfn3
uniprot id: A0A8C5NZ34
names: Similarity
messages: Belongs to the profilin family.

51337:Grin3b
gene id: 51337:Grin3b
uniprot id: A0A8C5L8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Jag1
gene id: 51337:Jag1
uniprot id: A0A8C5KWX0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

51337:Ppef2
gene id: 51337:Ppef2
uniprot id: A0A8C5LGY7
names: Similarity
messages: Belongs to the PPP phosphatase family.

51337:LOC101597500
gene id: 51337:LOC101597500
uniprot id: A0A8C5NZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine gamma family.
messages: Secreted

51337:Cdc14b
gene id: 51337:Cdc14b
uniprot id: A0A8C5JZT9
uniprot id: A0A8C5NUM8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

51337:Vps4a
gene id: 51337:Vps4a
uniprot id: A0A8C5KFR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

51337:LOC101607713
gene id: 51337:LOC101607713
uniprot id: A0A8C5K3D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

51337:LOC101595545
gene id: 51337:LOC101595545
uniprot id: A0A8C5K4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

51337:LOC101600145
gene id: 51337:LOC101600145
uniprot id: A0A8C5K993
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

51337:Igfbp4
gene id: 51337:Igfbp4
uniprot id: A0A8C5JWZ4
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Dcp2
gene id: 51337:Dcp2
uniprot id: A0A8C5NWI6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

51337:Tubb2b
gene id: 51337:Tubb2b
uniprot id: A0A8C5KCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Mrps18a
gene id: 51337:Mrps18a
uniprot id: A0A8C5K0D9
names: Subcellular Location Annotation
messages: Mitochondrion

51337:Apex2
gene id: 51337:Apex2
uniprot id: A0A8C5P2Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

51337:St7l
gene id: 51337:St7l
uniprot id: A0A8C5L1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

51337:LOC101597478
gene id: 51337:LOC101597478
uniprot id: A0A8C5KFP7
names: Similarity
messages: Belongs to the pro/parathymosin family.

51337:Rbm5
gene id: 51337:Rbm5
uniprot id: A0A8C5K3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

51337:Aipl1
gene id: 51337:Aipl1
uniprot id: A0A8C5LBZ6
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with NUB1.

51337:Derl3
gene id: 51337:Derl3
uniprot id: A0A8C5K484
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Lmf2
gene id: 51337:Lmf2
uniprot id: A0A8C5KQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

51337:Polr2c
gene id: 51337:Polr2c
uniprot id: A0A8C5P5C4
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

51337:Th
gene id: 51337:Th
uniprot id: A0A8C5KAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region
messages: synaptic vesicle

51337:Paqr5
gene id: 51337:Paqr5
uniprot id: A0A8C5KYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

51337:Vps41
gene id: 51337:Vps41
uniprot id: A0A8C5L5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

51337:LOC101598882
gene id: 51337:LOC101598882
uniprot id: A0A8C5P1N8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

51337:Cog7
gene id: 51337:Cog7
uniprot id: A0A8C5LDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Ccr3
gene id: 51337:Ccr3
uniprot id: A0A8C5JWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Hsf1
gene id: 51337:Hsf1
uniprot id: A0A8C5LMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

51337:Txnl4a
gene id: 51337:Txnl4a
uniprot id: A0A8C5KRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

51337:Opa1
gene id: 51337:Opa1
uniprot id: A0A8C5LBH6
uniprot id: A0A8C5LBY8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

51337:Rpl23
gene id: 51337:Rpl23
uniprot id: A0A8C5K454
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

51337:Capg
gene id: 51337:Capg
uniprot id: A0A8C5KBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

51337:Trmt61a
gene id: 51337:Trmt61a
uniprot id: A0A8C5JTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

51337:Satb2
gene id: 51337:Satb2
uniprot id: A0A8C5P2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

51337:Idua
gene id: 51337:Idua
uniprot id: A0A8C5K7P4
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

51337:Khdrbs3
gene id: 51337:Khdrbs3
uniprot id: A0A8C5KAR1
names: Similarity
messages: Belongs to the KHDRBS family.

51337:Med31
gene id: 51337:Med31
uniprot id: A0A8C5L5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

51337:Cks1b
gene id: 51337:Cks1b
uniprot id: A0A8C5JXC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

51337:LOC101603638
gene id: 51337:LOC101603638
uniprot id: A0A8C5NY50
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Lyve1
gene id: 51337:Lyve1
uniprot id: A0A8C5L1Z7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Bok
gene id: 51337:Bok
uniprot id: A0A8C5P4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

51337:Ptgds
gene id: 51337:Ptgds
uniprot id: A0A8C5KW50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Monomer.
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: Secreted
messages: perinuclear region

51337:Dbx1
gene id: 51337:Dbx1
uniprot id: A0A8C5KRU5
names: Subcellular Location Annotation
messages: Nucleus

51337:Slc14a2
gene id: 51337:Slc14a2
uniprot id: A0A8C5LAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

51337:Itgb8
gene id: 51337:Itgb8
uniprot id: A0A8C5K4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

51337:Mycbp2
gene id: 51337:Mycbp2
uniprot id: A0A8C5LFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

51337:Mchr1
gene id: 51337:Mchr1
uniprot id: A0A8C5KDQ7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

51337:Rbx1
gene id: 51337:Rbx1
uniprot id: A0A8C5P3M8
names: Similarity
messages: Belongs to the RING-box family.

51337:Nhsl1
gene id: 51337:Nhsl1
uniprot id: A0A8C5NVW7
names: Similarity
messages: Belongs to the NHS family.

51337:Stxbp3
gene id: 51337:Stxbp3
uniprot id: A0A8C5L9Y7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

51337:LOC101600650
gene id: 51337:LOC101600650
uniprot id: A0A8C5L6J6
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:Mdfic2
gene id: 51337:Mdfic2
uniprot id: A0A8C5NYG7
names: Similarity
messages: Belongs to the MDFI family.

51337:Polr3d
gene id: 51337:Polr3d
uniprot id: A0A8C5NVV8
names: Subcellular Location Annotation
messages: Nucleus

51337:Ube2e1
gene id: 51337:Ube2e1
uniprot id: A0A8C5P2V1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

51337:Krt82
gene id: 51337:Krt82
uniprot id: A0A8C5LH53
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Bambi
gene id: 51337:Bambi
uniprot id: A0A8C5LEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

51337:Traf6
gene id: 51337:Traf6
uniprot id: A0A8C5L1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

51337:Taf12
gene id: 51337:Taf12
uniprot id: A0A8C5L807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

51337:Dhdds
gene id: 51337:Dhdds
uniprot id: A0A8C5P311
names: Similarity
messages: Belongs to the UPP synthase family.

51337:Pcyox1
gene id: 51337:Pcyox1
uniprot id: A0A8C5K2X4
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

51337:Hoxb7
gene id: 51337:Hoxb7
uniprot id: A0A8C5NUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Tubgcp5
gene id: 51337:Tubgcp5
uniprot id: A0A8C5L0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

51337:Ipo13
gene id: 51337:Ipo13
uniprot id: A0A8C5L4P4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

51337:Tll1
gene id: 51337:Tll1
uniprot id: A0A8C5KI07
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Jpt1
gene id: 51337:Jpt1
uniprot id: A0A8C5KIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

51337:Mrpl16
gene id: 51337:Mrpl16
uniprot id: A0A8C5L1L0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

51337:Wnt3
gene id: 51337:Wnt3
uniprot id: A0A8C5L3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

51337:LOC101606988
gene id: 51337:LOC101606988
uniprot id: A0A8C5LI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

51337:Rdh11
gene id: 51337:Rdh11
uniprot id: A0A8C5KV48
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Wdr24
gene id: 51337:Wdr24
uniprot id: A0A8C5KUF7
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

51337:Hoxa6
gene id: 51337:Hoxa6
uniprot id: A0A8C5KVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Znf703
gene id: 51337:Znf703
uniprot id: A0A8C5JWF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

51337:Ndufa6
gene id: 51337:Ndufa6
uniprot id: A0A8C5L6X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

51337:Prkd2
gene id: 51337:Prkd2
uniprot id: A0A8C5NYV0
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

51337:Krt40
gene id: 51337:Krt40
uniprot id: A0A8C5L9G3
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Plppr2
gene id: 51337:Plppr2
uniprot id: A0A8C5NUU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

51337:Meis1
gene id: 51337:Meis1
uniprot id: A0A8C5KMA5
uniprot id: A0A8C5KQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

51337:Rpl8
gene id: 51337:Rpl8
uniprot id: A0A8C5K608
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

51337:Tmem200a
gene id: 51337:Tmem200a
uniprot id: A0A8C5JWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

51337:LOC101593899
gene id: 51337:LOC101593899
uniprot id: A0A8C5KBL8
names: Similarity
messages: Belongs to the AAA ATPase family.

51337:Top1
gene id: 51337:Top1
uniprot id: A0A8C5NYL9
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

51337:Cutc
gene id: 51337:Cutc
uniprot id: A0A8C5K987
names: Similarity
messages: Belongs to the CutC family.

51337:Wasf1
gene id: 51337:Wasf1
uniprot id: A0A8C5KLN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

51337:LOC101611175
gene id: 51337:LOC101611175
uniprot id: A0A8C5KVD7
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Mab21l2
gene id: 51337:Mab21l2
uniprot id: A0A8C5K2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

51337:Mrpl58
gene id: 51337:Mrpl58
uniprot id: A0A8C5JY09
names: Subcellular Location Annotation
messages: Mitochondrion

51337:Kbtbd8
gene id: 51337:Kbtbd8
uniprot id: A0A8C5LAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

51337:Rp2
gene id: 51337:Rp2
uniprot id: A0A8C5LE86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

51337:Fads3
gene id: 51337:Fads3
uniprot id: A0A8C5L566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

51337:Msx1
gene id: 51337:Msx1
uniprot id: A0A8C5KZL0
names: Subcellular Location Annotation
messages: Nucleus

51337:Kat8
gene id: 51337:Kat8
uniprot id: A0A8C5P0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

51337:Serpinb1
gene id: 51337:Serpinb1
uniprot id: A0A8C5KB39
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

51337:C11H16orf72
gene id: 51337:C11H16orf72
uniprot id: A0A8C5L075
names: Similarity
messages: Belongs to the TAPR1 family.

51337:B4galt6
gene id: 51337:B4galt6
uniprot id: A0A8C5JXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

51337:Cnnm2
gene id: 51337:Cnnm2
uniprot id: A0A8C5LFY9
uniprot id: A0A8C5LMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

51337:Rnps1
gene id: 51337:Rnps1
uniprot id: A0A8C5KNB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

51337:Rps10
gene id: 51337:Rps10
uniprot id: A0A8C5LBJ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

51337:Tp53rk
gene id: 51337:Tp53rk
uniprot id: A0A8C5KWW5
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

51337:N4bp3
gene id: 51337:N4bp3
uniprot id: A0A8C5LI82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

51337:Prrc1
gene id: 51337:Prrc1
uniprot id: A0A8C5KC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

51337:Ambn
gene id: 51337:Ambn
uniprot id: A0A8C5L5D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

51337:Tafazzin
gene id: 51337:Tafazzin
uniprot id: A0A8C5KK43
uniprot id: A0A8C5KM09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

51337:Xpo1
gene id: 51337:Xpo1
uniprot id: A0A8C5LAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

51337:LOC101614465
gene id: 51337:LOC101614465
uniprot id: A0A8C5K0S8
names: Similarity
messages: Belongs to the cytochrome P450 family.

51337:Prkar1a
gene id: 51337:Prkar1a
uniprot id: A0A8C5L2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

51337:Fscn2
gene id: 51337:Fscn2
uniprot id: A0A8C5KSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

51337:Exoc3l4
gene id: 51337:Exoc3l4
uniprot id: A0A8C5K8W9
names: Similarity
messages: Belongs to the SEC6 family.

51337:Mapk14
gene id: 51337:Mapk14
uniprot id: A0A8C5KUC7
uniprot id: A0A8C5KXB7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

51337:Tnf
gene id: 51337:Tnf
uniprot id: A0A8C5JVT1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

51337:Letm1
gene id: 51337:Letm1
uniprot id: A0A8C5LIT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Pofut1
gene id: 51337:Pofut1
uniprot id: A0A8C5K549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 65 family.
messages: Endoplasmic reticulum

51337:Eif4ebp1
gene id: 51337:Eif4ebp1
uniprot id: A0A8C5KDZ1
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

51337:Sebox
gene id: 51337:Sebox
uniprot id: A0A8C5L500
names: Subcellular Location Annotation
messages: Nucleus

51337:Naaladl1
gene id: 51337:Naaladl1
uniprot id: A0A8C5LD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

51337:Fev
gene id: 51337:Fev
uniprot id: A0A8C5KGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Ccdc153
gene id: 51337:Ccdc153
uniprot id: A0A8C5KTQ9
names: Similarity
messages: Belongs to the UPF0610 family.

51337:Kat2a
gene id: 51337:Kat2a
uniprot id: A0A8C5L9P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

51337:Ano4
gene id: 51337:Ano4
uniprot id: A0A8C5P3W0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Lyrm2
gene id: 51337:Lyrm2
uniprot id: A0A8C5L6S7
names: Similarity
messages: Belongs to the complex I LYR family.

51337:Clic3
gene id: 51337:Clic3
uniprot id: A0A8C5L9E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

51337:Isyna1
gene id: 51337:Isyna1
uniprot id: A0A8C5LJ37
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

51337:Fut2
gene id: 51337:Fut2
uniprot id: A0A8C5KE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

51337:Slc6a9
gene id: 51337:Slc6a9
uniprot id: A0A8C5KN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

51337:Epgn
gene id: 51337:Epgn
uniprot id: A0A8C5KRL4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Ip6k2
gene id: 51337:Ip6k2
uniprot id: A0A8C5LBD0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

51337:Scd5
gene id: 51337:Scd5
uniprot id: A0A8C5LHA1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

51337:Rsrp1
gene id: 51337:Rsrp1
uniprot id: A0A8C5JX00
names: Similarity
messages: Belongs to the RSRP family.

51337:Rock2
gene id: 51337:Rock2
uniprot id: A0A8C5JUS6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

51337:LOC101611810
gene id: 51337:LOC101611810
uniprot id: A0A8C5P2Y0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

51337:Gipc1
gene id: 51337:Gipc1
uniprot id: A0A8C5K2K9
names: Similarity
messages: Belongs to the GIPC family.

51337:Taf6l
gene id: 51337:Taf6l
uniprot id: A0A8C5KS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

51337:Cops5
gene id: 51337:Cops5
uniprot id: A0A8C5K5H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

51337:LOC101594352
gene id: 51337:LOC101594352
uniprot id: A0A8C5KEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Ankrd34c
gene id: 51337:Ankrd34c
uniprot id: A0A8C5K4Y8
names: Similarity
messages: Belongs to the ANKRD34 family.

51337:Gas6
gene id: 51337:Gas6
uniprot id: A0A8C5L1J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Tcf25
gene id: 51337:Tcf25
uniprot id: A0A8C5L5X3
names: Similarity
messages: Belongs to the TCF25 family.

51337:Mmp2
gene id: 51337:Mmp2
uniprot id: A0A8C5KA84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.
messages: extracellular matrix

51337:Kctd10
gene id: 51337:Kctd10
uniprot id: A0A8C5KI82
names: Similarity
messages: Belongs to the BACURD family.

51337:Ntn4
gene id: 51337:Ntn4
uniprot id: A0A8C5K7N9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Tmbim4
gene id: 51337:Tmbim4
uniprot id: A0A8C5LH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

51337:Chac2
gene id: 51337:Chac2
uniprot id: A0A8C5LF17
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

51337:LOC101609404
gene id: 51337:LOC101609404
uniprot id: A0A8C5KR02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

51337:Mtmr1
gene id: 51337:Mtmr1
uniprot id: A0A8C5L402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

51337:Manba
gene id: 51337:Manba
uniprot id: A0A8C5KFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

51337:Arpc1b
gene id: 51337:Arpc1b
uniprot id: A0A8C5NX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

51337:Slco1b3
gene id: 51337:Slco1b3
uniprot id: A0A8C5KIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

51337:Hlf
gene id: 51337:Hlf
uniprot id: A0A8C5NZM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

51337:Chrm4
gene id: 51337:Chrm4
uniprot id: A0A8C5K5B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

51337:Tlcd5
gene id: 51337:Tlcd5
uniprot id: A0A8C5KIG4
names: Subcellular Location Annotation
messages: Membrane

51337:Foxn1
gene id: 51337:Foxn1
uniprot id: A0A8C5P4S4
names: Subcellular Location Annotation
messages: Nucleus

51337:Tmcc1
gene id: 51337:Tmcc1
uniprot id: A0A8C5L2V2
names: Similarity
messages: Belongs to the TEX28 family.

51337:Eno3
gene id: 51337:Eno3
uniprot id: A0A8C5KQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

51337:Foxb1
gene id: 51337:Foxb1
uniprot id: A0A8C5K622
names: Subcellular Location Annotation
messages: Nucleus

51337:Rhbdf1
gene id: 51337:Rhbdf1
uniprot id: A0A8C5K1N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

51337:LOC101608081
gene id: 51337:LOC101608081
uniprot id: A0A8C5K3E3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

51337:LOC101597793
gene id: 51337:LOC101597793
uniprot id: A0A8C5KE66
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

51337:Nhp2
gene id: 51337:Nhp2
uniprot id: A0A8C5KXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

51337:KEG00 p13
gene id: 51337:KEG00_p13
uniprot id: Q710T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Asf1b
gene id: 51337:Asf1b
uniprot id: A0A8C5LCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

51337:Xk
gene id: 51337:Xk
uniprot id: A0A8C5JV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

51337:Tmem218
gene id: 51337:Tmem218
uniprot id: A0A8C5KXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

51337:Polr2d
gene id: 51337:Polr2d
uniprot id: A0A8C5NZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

51337:Ppme1
gene id: 51337:Ppme1
uniprot id: A0A8C5K6U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

51337:Umps
gene id: 51337:Umps
uniprot id: A0A8C5K649
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

51337:Rplp2
gene id: 51337:Rplp2
uniprot id: A0A8C5KI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

51337:LOC101613658
gene id: 51337:LOC101613658
uniprot id: A0A8C5K5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

51337:Npc2
gene id: 51337:Npc2
uniprot id: A0A8C5KT80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

51337:Mycl
gene id: 51337:Mycl
uniprot id: A0A8C5NXC2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

51337:Crybb2
gene id: 51337:Crybb2
uniprot id: A0A8C5KV30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

51337:Fus
gene id: 51337:Fus
uniprot id: A0A8C5NXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

51337:Snrpc
gene id: 51337:Snrpc
uniprot id: A0A8C5P402
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

51337:Mrpl41
gene id: 51337:Mrpl41
uniprot id: A0A8C5KFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

51337:Ccng1
gene id: 51337:Ccng1
uniprot id: A0A8C5LD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

51337:Zpr1
gene id: 51337:Zpr1
uniprot id: A0A8C5L4U8
names: Similarity
messages: Belongs to the ZPR1 family.

51337:Kif5a
gene id: 51337:Kif5a
uniprot id: A0A8C5P1Q7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

51337:Gpm6b
gene id: 51337:Gpm6b
uniprot id: A0A8C5K9A1
uniprot id: A0A8C5K9B1
uniprot id: A0A8C5KBY3
uniprot id: A0A8C5NWV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

51337:Med30
gene id: 51337:Med30
uniprot id: A0A8C5P476
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

51337:Padi2
gene id: 51337:Padi2
uniprot id: A0A8C5K2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

51337:Slc6a7
gene id: 51337:Slc6a7
uniprot id: A0A8C5LC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:Dgke
gene id: 51337:Dgke
uniprot id: A0A8C5P4W9
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

51337:LOC101612189
gene id: 51337:LOC101612189
uniprot id: A0A8C5NZ21
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

51337:Vma21
gene id: 51337:Vma21
uniprot id: A0A8C5L6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

51337:Arpp19
gene id: 51337:Arpp19
uniprot id: A0A8C5KHR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

51337:Trmt11
gene id: 51337:Trmt11
uniprot id: A0A8C5KTM6
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

51337:Cnr1
gene id: 51337:Cnr1
uniprot id: A0A8C5KD85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

51337:Gpat4
gene id: 51337:Gpat4
uniprot id: A0A8C5KDV9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

51337:H1-2
gene id: 51337:H1-2
uniprot id: A0A8C5NYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

51337:Abcg4
gene id: 51337:Abcg4
uniprot id: A0A8C5P237
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

51337:Gpsm2
gene id: 51337:Gpsm2
uniprot id: A0A8C5L9C2
names: Similarity
messages: Belongs to the GPSM family.

51337:Cldn10
gene id: 51337:Cldn10
uniprot id: A0A8C5K8A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Emc7
gene id: 51337:Emc7
uniprot id: A0A8C5JWH7
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

51337:Sec22a
gene id: 51337:Sec22a
uniprot id: A0A8C5KQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

51337:Pdlim1
gene id: 51337:Pdlim1
uniprot id: A0A8C5P0I9
names: Subcellular Location Annotation
messages: Z line

51337:Rprd1b
gene id: 51337:Rprd1b
uniprot id: A0A8C5KXR2
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

51337:G6pc2
gene id: 51337:G6pc2
uniprot id: A0A8C5P4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

51337:Ccnd3
gene id: 51337:Ccnd3
uniprot id: A0A8C5L5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

51337:Steap2
gene id: 51337:Steap2
uniprot id: A0A8C5K9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

51337:Polr2i
gene id: 51337:Polr2i
uniprot id: A0A8C5KLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

51337:Gnai3
gene id: 51337:Gnai3
uniprot id: A0A8C5P5E7
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

51337:St6galnac5
gene id: 51337:St6galnac5
uniprot id: A0A8C5P0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Pyroxd1
gene id: 51337:Pyroxd1
uniprot id: A0A8C5KQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

51337:Plxna3
gene id: 51337:Plxna3
uniprot id: A0A8C5L5T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Hoxb6
gene id: 51337:Hoxb6
uniprot id: A0A8C5JVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:Kcnj4
gene id: 51337:Kcnj4
uniprot id: A0A8C5NWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

51337:Eif4ebp2
gene id: 51337:Eif4ebp2
uniprot id: A0A8C5KYS8
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

51337:Krt20
gene id: 51337:Krt20
uniprot id: A0A8C5LCH4
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Sdhaf1
gene id: 51337:Sdhaf1
uniprot id: A0A8C5KAB3
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

51337:Map3k11
gene id: 51337:Map3k11
uniprot id: A0A8C5K9J0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

51337:LOC101605743
gene id: 51337:LOC101605743
uniprot id: A0A8C5LHH9
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

51337:Desi1
gene id: 51337:Desi1
uniprot id: A0A8C5L5V4
names: Similarity
messages: Belongs to the DeSI family.

51337:Lhx8
gene id: 51337:Lhx8
uniprot id: A0A8C5KXJ9
names: Subcellular Location Annotation
messages: Nucleus

51337:Hddc2
gene id: 51337:Hddc2
uniprot id: A0A8C5JXP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

51337:Crhr1
gene id: 51337:Crhr1
uniprot id: A0A8C5P025
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Membrane

51337:Prok1
gene id: 51337:Prok1
uniprot id: A0A8C5LKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

51337:Stx1b
gene id: 51337:Stx1b
uniprot id: A0A8C5JZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

51337:Sfxn2
gene id: 51337:Sfxn2
uniprot id: A0A8C5L8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

51337:B4galt3
gene id: 51337:B4galt3
uniprot id: A0A8C5LC54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

51337:Unc119
gene id: 51337:Unc119
uniprot id: A0A8C5P333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDE6D/unc-119 family.
messages: spindle

51337:Sumo3
gene id: 51337:Sumo3
uniprot id: A0A8C5KEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

51337:Hoxc5
gene id: 51337:Hoxc5
uniprot id: A0A8C5L900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

51337:LOC101597669
gene id: 51337:LOC101597669
uniprot id: A0A8C5LHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Ampd2
gene id: 51337:Ampd2
uniprot id: A0A8C5L958
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Homotetramer.

51337:Ywhaq
gene id: 51337:Ywhaq
uniprot id: A0A8C5K5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

51337:Mmp14
gene id: 51337:Mmp14
uniprot id: A0A8C5K088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome

51337:LOC101608835
gene id: 51337:LOC101608835
uniprot id: A0A8C5L3X5
names: Subcellular Location Annotation
messages: Secreted

51337:Tubb3
gene id: 51337:Tubb3
uniprot id: A0A8C5P103
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Rc3h2
gene id: 51337:Rc3h2
uniprot id: A0A8C5LHF7
names: Subcellular Location Annotation
messages: P-body

51337:Kcnab3
gene id: 51337:Kcnab3
uniprot id: A0A8C5K3A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

51337:Fth1
gene id: 51337:Fth1
uniprot id: A0A8C5KBE5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

51337:Tp63
gene id: 51337:Tp63
uniprot id: A0A8C5LME2
uniprot id: A0A8C5P679
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Nucleus

51337:Bnip3l
gene id: 51337:Bnip3l
uniprot id: A0A8C5L9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

51337:Ankh
gene id: 51337:Ankh
uniprot id: A0A8C5KC20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

51337:Slc35a3
gene id: 51337:Slc35a3
uniprot id: A0A8C5KYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

51337:Prom2
gene id: 51337:Prom2
uniprot id: A0A8C5KLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

51337:Slc25a32
gene id: 51337:Slc25a32
uniprot id: A0A8C5JXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Cct5
gene id: 51337:Cct5
uniprot id: A0A8C5KDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

51337:Fam167b
gene id: 51337:Fam167b
uniprot id: A0A8C5KSM2
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

51337:Dynlt2
gene id: 51337:Dynlt2
uniprot id: A0A8C5L794
uniprot id: A0A8C5P3F8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

51337:Lrp12
gene id: 51337:Lrp12
uniprot id: A0A8C5L2N0
uniprot id: A0A8C5P3K2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Kcnk12
gene id: 51337:Kcnk12
uniprot id: A0A8C5LJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

51337:Dolpp1
gene id: 51337:Dolpp1
uniprot id: A0A8C5LIG7
uniprot id: A0A8C5P5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

51337:Gnrhr
gene id: 51337:Gnrhr
uniprot id: A0A8C5KRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Ednra
gene id: 51337:Ednra
uniprot id: A0A8C5P2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

51337:Susd6
gene id: 51337:Susd6
uniprot id: A0A8C5K573
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Plau
gene id: 51337:Plau
uniprot id: A0A8C5LBH0
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

51337:Ap1s2
gene id: 51337:Ap1s2
uniprot id: A0A8C5L3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

51337:LOC101604968
gene id: 51337:LOC101604968
uniprot id: A0A8C5K746
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:Dpcd
gene id: 51337:Dpcd
uniprot id: A0A8C5NWQ3
names: Similarity
messages: Belongs to the DPCD family.

51337:Npm3
gene id: 51337:Npm3
uniprot id: A0A8C5L1N9
names: Similarity
messages: Belongs to the nucleoplasmin family.

51337:Epha3
gene id: 51337:Epha3
uniprot id: A0A8C5LCU8
names: Subcellular Location Annotation
messages: Membrane

51337:Anapc16
gene id: 51337:Anapc16
uniprot id: A0A8C5P012
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

51337:LOC101607995
gene id: 51337:LOC101607995
uniprot id: A0A8C5KCI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

51337:Dnm1
gene id: 51337:Dnm1
uniprot id: A0A8C5JZ47
uniprot id: A0A8C5K330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

51337:LOC101615383
gene id: 51337:LOC101615383
uniprot id: A0A8C5KBJ2
names: Similarity
messages: Belongs to the strictosidine synthase family.

51337:Stag1
gene id: 51337:Stag1
uniprot id: A0A8C5KEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

51337:Ren
gene id: 51337:Ren
uniprot id: A0A8C5LBQ5
names: Similarity
messages: Belongs to the peptidase A1 family.

51337:Gadd45b
gene id: 51337:Gadd45b
uniprot id: A0A8C5L7Z4
names: Similarity
messages: Belongs to the GADD45 family.

51337:Lmod1
gene id: 51337:Lmod1
uniprot id: A0A8C5KRC6
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

51337:Tm4sf20
gene id: 51337:Tm4sf20
uniprot id: A0A8C5KI54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

51337:Fundc1
gene id: 51337:Fundc1
uniprot id: A0A8C5KHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

51337:Chrm3
gene id: 51337:Chrm3
uniprot id: A0A8C5NUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

51337:Psd2
gene id: 51337:Psd2
uniprot id: A0A8C5K8R9
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

51337:Cacna2d2
gene id: 51337:Cacna2d2
uniprot id: A0A8C5KZY3
uniprot id: A0A8C5P1L3
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

51337:Samm50
gene id: 51337:Samm50
uniprot id: A0A8C5LHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

51337:Tagln2
gene id: 51337:Tagln2
uniprot id: A0A8C5KHN7
names: Similarity
messages: Belongs to the calponin family.

51337:Fcer1g
gene id: 51337:Fcer1g
uniprot id: A0A8C5L877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

51337:Ric3
gene id: 51337:Ric3
uniprot id: A0A8C5K7T7
names: Similarity
messages: Belongs to the ric-3 family.

51337:Rps6ka3
gene id: 51337:Rps6ka3
uniprot id: A0A8C5P138
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

51337:Usp22
gene id: 51337:Usp22
uniprot id: A0A8C5L7I5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

51337:Vldlr
gene id: 51337:Vldlr
uniprot id: A0A8C5KT99
uniprot id: A0A8C5KUP3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: clathrin-coated pit

51337:Dgkz
gene id: 51337:Dgkz
uniprot id: A0A8C5K177
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

51337:Rgr
gene id: 51337:Rgr
uniprot id: A0A8C5P2P1
names: Subcellular Location Annotation
messages: Membrane

51337:Sgf29
gene id: 51337:Sgf29
uniprot id: A0A8C5K6U7
names: Subcellular Location Annotation
messages: Nucleus

51337:Suclg1
gene id: 51337:Suclg1
uniprot id: A0A8C5LJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

51337:Prox1
gene id: 51337:Prox1
uniprot id: A0A8C5KMZ0
names: Subcellular Location Annotation
messages: Nucleus

51337:Plk1
gene id: 51337:Plk1
uniprot id: A0A8C5L8W8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

51337:Phtf1
gene id: 51337:Phtf1
uniprot id: A0A8C5KZX4
uniprot id: A0A8C5L3F9
names: Subcellular Location Annotation
messages: Membrane

51337:Tbccd1
gene id: 51337:Tbccd1
uniprot id: A0A8C5K178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

51337:Trhr
gene id: 51337:Trhr
uniprot id: A0A8C5L609
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

51337:Dhps
gene id: 51337:Dhps
uniprot id: A0A8C5L4V6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

51337:Trmo
gene id: 51337:Trmo
uniprot id: A0A8C5KJW7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

51337:Dppa5
gene id: 51337:Dppa5
uniprot id: A0A8C5KHW0
names: Similarity
messages: Belongs to the KHDC1 family.

51337:Spon2
gene id: 51337:Spon2
uniprot id: A0A8C5NX26
names: Subcellular Location Annotation
messages: extracellular matrix

51337:Chmp2b
gene id: 51337:Chmp2b
uniprot id: A0A8C5K644
names: Similarity
messages: Belongs to the SNF7 family.

51337:Ism1
gene id: 51337:Ism1
uniprot id: A0A8C5KKZ2
names: Similarity
messages: Belongs to the isthmin family.

51337:Pfas
gene id: 51337:Pfas
uniprot id: A0A8C5LIX6
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

51337:Ackr4
gene id: 51337:Ackr4
uniprot id: A0A8C5KD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Tfb1m
gene id: 51337:Tfb1m
uniprot id: A0A8C5L9V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Interacts with mitochondrial RNA polymerase POLRMT. Interacts with TFAM.
messages: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

51337:Tcea1
gene id: 51337:Tcea1
uniprot id: A0A8C5P313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

51337:Ptch1
gene id: 51337:Ptch1
uniprot id: A0A8C5KVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

51337:Galnt9
gene id: 51337:Galnt9
uniprot id: A0A8C5LHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Camlg
gene id: 51337:Camlg
uniprot id: A0A8C5LBZ7
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

51337:Med29
gene id: 51337:Med29
uniprot id: A0A8C5KBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

51337:Smim5
gene id: 51337:Smim5
uniprot id: A0A8C5K921
names: Subcellular Location Annotation
messages: Membrane

51337:Otud5
gene id: 51337:Otud5
uniprot id: A0A8C5KM50
names: Similarity
messages: Belongs to the peptidase C85 family.

51337:Ppp1r3c
gene id: 51337:Ppp1r3c
uniprot id: A0A8C5LDZ9
names: Domain
names: Function
names: Subunit
messages: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
messages: Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.
messages: The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase.

51337:Unc50
gene id: 51337:Unc50
uniprot id: A0A8C5NVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

51337:Neu1
gene id: 51337:Neu1
uniprot id: A0A8C5NZX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

51337:Slc39a2
gene id: 51337:Slc39a2
uniprot id: A0A8C5P0T8
names: Subcellular Location Annotation
messages: Membrane

51337:Pygm
gene id: 51337:Pygm
uniprot id: A0A8C5KKH0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

51337:Necap1
gene id: 51337:Necap1
uniprot id: A0A8C5KB99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

51337:Cltrn
gene id: 51337:Cltrn
uniprot id: A0A8C5JVI7
names: Subcellular Location Annotation
messages: Membrane

51337:Elf2
gene id: 51337:Elf2
uniprot id: A0A8C5JWU4
uniprot id: A0A8C5JYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Slc35f6
gene id: 51337:Slc35f6
uniprot id: A0A8C5KD50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

51337:Uchl5
gene id: 51337:Uchl5
uniprot id: A0A8C5L0C1
names: Similarity
messages: Belongs to the peptidase C12 family.

51337:Neurod1
gene id: 51337:Neurod1
uniprot id: A0A8C5KYP2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

51337:Myh1
gene id: 51337:Myh1
uniprot id: A0A8C5KA43
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

51337:Fam234a
gene id: 51337:Fam234a
uniprot id: A0A8C5LBK9
names: Similarity
messages: Belongs to the FAM234 family.

51337:Nipal2
gene id: 51337:Nipal2
uniprot id: A0A8C5NU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

51337:Tcp11l2
gene id: 51337:Tcp11l2
uniprot id: A0A8C5K087
names: Similarity
messages: Belongs to the TCP11 family.

51337:Cnksr2
gene id: 51337:Cnksr2
uniprot id: A0A8C5KUU2
uniprot id: A0A8C5KWB0
names: Similarity
messages: Belongs to the CNKSR family.

51337:Htr6
gene id: 51337:Htr6
uniprot id: A0A8C5L4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Scamp3
gene id: 51337:Scamp3
uniprot id: A0A8C5L5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

51337:Rab14
gene id: 51337:Rab14
uniprot id: A0A8C5KE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

51337:Alb
gene id: 51337:Alb
uniprot id: A0A8C5K0T6
names: Subcellular Location Annotation
messages: Secreted

51337:Septin5
gene id: 51337:Septin5
uniprot id: A0A8C5NTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cytoskeleton

51337:Krt79
gene id: 51337:Krt79
uniprot id: A0A8C5NYG9
names: Similarity
messages: Belongs to the intermediate filament family.

51337:LOC101604979
gene id: 51337:LOC101604979
uniprot id: A0A8C5L9N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

51337:Nefh
gene id: 51337:Nefh
uniprot id: A0A8C5LE23
names: Similarity
messages: Belongs to the intermediate filament family.

51337:Evl
gene id: 51337:Evl
uniprot id: A0A8C5K7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: lamellipodium
messages: stress fiber

51337:LOC101615877
gene id: 51337:LOC101615877
uniprot id: A0A8C5KJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Cryaa
gene id: 51337:Cryaa
uniprot id: A0A8C5K894
uniprot id: A0A8C5K919
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

51337:Apex1
gene id: 51337:Apex1
uniprot id: A0A8C5NXI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

51337:Gfod1
gene id: 51337:Gfod1
uniprot id: A0A8C5JZA7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

51337:Dnajc27
gene id: 51337:Dnajc27
uniprot id: A0A8C5P0Z2
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

51337:Slc25a45
gene id: 51337:Slc25a45
uniprot id: A0A8C5KX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

51337:Dhfr
gene id: 51337:Dhfr
uniprot id: A0A8C5K955
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

51337:Kcnmb1
gene id: 51337:Kcnmb1
uniprot id: A0A8C5L372
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

51337:Asb12
gene id: 51337:Asb12
uniprot id: A0A8C5LK89
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

51337:Otx2
gene id: 51337:Otx2
uniprot id: A0A8C5KD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

51337:Ncstn
gene id: 51337:Ncstn
uniprot id: A0A8C5L1Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

51337:Fbp2
gene id: 51337:Fbp2
uniprot id: A0A8C5LFI7
names: Similarity
messages: Belongs to the FBPase class 1 family.

51337:Gdf9
gene id: 51337:Gdf9
uniprot id: A0A8C5K4H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

51337:LOC101598970
gene id: 51337:LOC101598970
uniprot id: A0A8C5KEK1
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101613497
gene id: 51337:LOC101613497
uniprot id: A0A8C5JZJ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

51337:Dok4
gene id: 51337:Dok4
uniprot id: A0A8C5LCA6
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

51337:Traf2
gene id: 51337:Traf2
uniprot id: A0A8C5L9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

51337:Rtn3
gene id: 51337:Rtn3
uniprot id: A0A8C5KTZ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101617155
gene id: 51337:LOC101617155
uniprot id: A0A8C5KKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Slitrk6
gene id: 51337:Slitrk6
uniprot id: A0A8C5LG12
names: Similarity
messages: Belongs to the SLITRK family.

51337:LOC101597951
gene id: 51337:LOC101597951
uniprot id: A0A8C5P030
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

51337:Trnt1
gene id: 51337:Trnt1
uniprot id: A0A8C5KW98
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

51337:Neurod2
gene id: 51337:Neurod2
uniprot id: A0A8C5K4D7
names: Subcellular Location Annotation
messages: Nucleus

51337:Actbl2
gene id: 51337:Actbl2
uniprot id: A0A8C5NZN5
names: Similarity
messages: Belongs to the actin family.

51337:Nnat
gene id: 51337:Nnat
uniprot id: A0A8C5L204
uniprot id: A0A8C5LAB5
names: Similarity
messages: Belongs to the neuronatin family.

51337:Spata6
gene id: 51337:Spata6
uniprot id: A0A8C5KAX9
names: Similarity
messages: Belongs to the SPATA6 family.

51337:Rpl24
gene id: 51337:Rpl24
uniprot id: A0A8C5KUD0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

51337:KEG00 p03
gene id: 51337:KEG00_p03
uniprot id: Q710S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Tenm2
gene id: 51337:Tenm2
uniprot id: A0A8C5LB86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Crygs
gene id: 51337:Crygs
uniprot id: A0A8C5KGP9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Tmem39b
gene id: 51337:Tmem39b
uniprot id: A0A8C5NWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

51337:LOC101608666
gene id: 51337:LOC101608666
uniprot id: A0A8C5K8H1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

51337:Ppp3ca
gene id: 51337:Ppp3ca
uniprot id: A0A8C5KAJ0
uniprot id: A0A8C5KDM1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

51337:LOC101612876
gene id: 51337:LOC101612876
uniprot id: A0A8C5K7U3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Rae1
gene id: 51337:Rae1
uniprot id: A0A8C5KX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

51337:Atg12
gene id: 51337:Atg12
uniprot id: A0A8C5KHM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

51337:Tm9sf1
gene id: 51337:Tm9sf1
uniprot id: A0A8C5KEB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

51337:Spns1
gene id: 51337:Spns1
uniprot id: A0A8C5LK40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

51337:Syt1
gene id: 51337:Syt1
uniprot id: A0A8C5LJK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

51337:Spsb4
gene id: 51337:Spsb4
uniprot id: A0A8C5L4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

51337:Preb
gene id: 51337:Preb
uniprot id: A0A8C5NUK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

51337:Gpr157
gene id: 51337:Gpr157
uniprot id: A0A8C5KG65
names: Subcellular Location Annotation
messages: Membrane

51337:Arf5
gene id: 51337:Arf5
uniprot id: A0A8C5K5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

51337:Hspb3
gene id: 51337:Hspb3
uniprot id: A0A8C5KK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

51337:Dvl2
gene id: 51337:Dvl2
uniprot id: A0A8C5K5P3
names: Similarity
messages: Belongs to the DSH family.

51337:Me3
gene id: 51337:Me3
uniprot id: A0A8C5LGF8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

51337:Dlg1
gene id: 51337:Dlg1
uniprot id: A0A8C5LB11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

51337:Septin7
gene id: 51337:Septin7
uniprot id: A0A8C5NWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

51337:LOC101616119
gene id: 51337:LOC101616119
uniprot id: A0A8C5NUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Tprg1l
gene id: 51337:Tprg1l
uniprot id: A0A8C5KS01
names: Similarity
messages: Belongs to the TPRG1 family.

51337:Tusc3
gene id: 51337:Tusc3
uniprot id: A0A8C5KVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:LOC101598410
gene id: 51337:LOC101598410
uniprot id: A0A8C5KSJ7
names: Subcellular Location Annotation
messages: Nucleus

51337:Ubp1
gene id: 51337:Ubp1
uniprot id: A0A8C5LCZ3
uniprot id: A0A8C5P4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

51337:Ppp1r14a
gene id: 51337:Ppp1r14a
uniprot id: A0A8C5KYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

51337:Gpn3
gene id: 51337:Gpn3
uniprot id: A0A8C5K3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

51337:Arsi
gene id: 51337:Arsi
uniprot id: A0A8C5K017
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

51337:Fam32a
gene id: 51337:Fam32a
uniprot id: A0A8C5LFS1
names: Similarity
messages: Belongs to the FAM32 family.

51337:Igfbp5
gene id: 51337:Igfbp5
uniprot id: A0A8C5KXS1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

51337:Esrp1
gene id: 51337:Esrp1
uniprot id: A0A8C5K0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

51337:Tubb4b
gene id: 51337:Tubb4b
uniprot id: A0A8C5L8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

51337:Tmem168
gene id: 51337:Tmem168
uniprot id: A0A8C5L0C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

51337:Grik3
gene id: 51337:Grik3
uniprot id: A0A8C5P1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Slc40a1
gene id: 51337:Slc40a1
uniprot id: A0A8C5K0X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

51337:Ccnc
gene id: 51337:Ccnc
uniprot id: A0A8C5KH63
uniprot id: A0A8C5KJI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

51337:Ufc1
gene id: 51337:Ufc1
uniprot id: A0A8C5K4W5
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

51337:Srp9
gene id: 51337:Srp9
uniprot id: A0A8C5KUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

51337:Crygn
gene id: 51337:Crygn
uniprot id: A0A8C5K9V1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:B3gat2
gene id: 51337:B3gat2
uniprot id: A0A8C5L4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Cdh15
gene id: 51337:Cdh15
uniprot id: A0A8C5K0Q5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

51337:Mettl26
gene id: 51337:Mettl26
uniprot id: A0A8C5KWA5
names: Similarity
messages: Belongs to the UPF0585 family.

51337:Ubac1
gene id: 51337:Ubac1
uniprot id: A0A8C5KKG3
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Inhbc
gene id: 51337:Inhbc
uniprot id: A0A8C5P5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

51337:Vps8
gene id: 51337:Vps8
uniprot id: A0A8C5LMI3
names: Similarity
messages: Belongs to the VPS8 family.

51337:Scrn1
gene id: 51337:Scrn1
uniprot id: A0A8C5KW38
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

51337:Hars1
gene id: 51337:Hars1
uniprot id: A0A8C5LEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

51337:Gtf2h3
gene id: 51337:Gtf2h3
uniprot id: A0A8C5KIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

51337:St6galnac4
gene id: 51337:St6galnac4
uniprot id: A0A8C5L5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

51337:Pgd
gene id: 51337:Pgd
uniprot id: A0A8C5NXW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

51337:Prxl2a
gene id: 51337:Prxl2a
uniprot id: A0A8C5P455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.
messages: Cytoplasm

51337:Rad1
gene id: 51337:Rad1
uniprot id: A0A8C5KQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

51337:Mapk1
gene id: 51337:Mapk1
uniprot id: A0A8C5LGI3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola

51337:LOC101612140
gene id: 51337:LOC101612140
uniprot id: A0A8C5KHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

51337:Wscd2
gene id: 51337:Wscd2
uniprot id: A0A8C5L455
names: Similarity
messages: Belongs to the WSCD family.

51337:Lin54
gene id: 51337:Lin54
uniprot id: A0A8C5L6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

51337:Emc1
gene id: 51337:Emc1
uniprot id: A0A8C5L086
uniprot id: A0A8C5P1T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

51337:Btg4
gene id: 51337:Btg4
uniprot id: A0A8C5KR86
names: Similarity
messages: Belongs to the BTG family.

51337:Hadh
gene id: 51337:Hadh
uniprot id: A0A8C5P0F6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

51337:Lhx6
gene id: 51337:Lhx6
uniprot id: A0A8C5L7X9
names: Subcellular Location Annotation
messages: Nucleus

51337:Sgms2
gene id: 51337:Sgms2
uniprot id: A0A8C5KU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

51337:Nup50
gene id: 51337:Nup50
uniprot id: A0A8C5KZC8
names: Subcellular Location Annotation
messages: nuclear pore complex

51337:Pde6g
gene id: 51337:Pde6g
uniprot id: A0A8C5P0F9
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

51337:Dll1
gene id: 51337:Dll1
uniprot id: A0A8C5K8I4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

51337:Cldn18
gene id: 51337:Cldn18
uniprot id: A0A8C5KY07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

51337:Pla2g4a
gene id: 51337:Pla2g4a
uniprot id: A0A8C5LIN8
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

51337:Timm22
gene id: 51337:Timm22
uniprot id: A0A8C5K314
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Dkk1
gene id: 51337:Dkk1
uniprot id: A0A8C5NUP5
names: Similarity
messages: Belongs to the dickkopf family.

51337:Nkain4
gene id: 51337:Nkain4
uniprot id: A0A8C5KMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

51337:Gab3
gene id: 51337:Gab3
uniprot id: A0A8C5KC43
names: Similarity
messages: Belongs to the GAB family.

51337:Tut1
gene id: 51337:Tut1
uniprot id: A0A8C5LCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

51337:LOC101605587
gene id: 51337:LOC101605587
uniprot id: A0A8C5L198
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

51337:Gnpnat1
gene id: 51337:Gnpnat1
uniprot id: A0A8C5LDP2
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

51337:Tinagl1
gene id: 51337:Tinagl1
uniprot id: A0A8C5L758
names: Similarity
messages: Belongs to the peptidase C1 family.

51337:B3gnt2
gene id: 51337:B3gnt2
uniprot id: A0A8C5NVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

51337:Eef1a2
gene id: 51337:Eef1a2
uniprot id: A0A8C5L816
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

51337:Cavin3
gene id: 51337:Cavin3
uniprot id: A0A8C5LD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

51337:Armcx3
gene id: 51337:Armcx3
uniprot id: A0A8C5LJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:Vps26b
gene id: 51337:Vps26b
uniprot id: A0A8C5KV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

51337:Prkaca
gene id: 51337:Prkaca
uniprot id: A0A8C5P3W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Cell membrane
messages: Membrane

51337:Sesn2
gene id: 51337:Sesn2
uniprot id: A0A8C5KC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

51337:Slc30a9
gene id: 51337:Slc30a9
uniprot id: A0A8C5KWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

51337:Tm6sf2
gene id: 51337:Tm6sf2
uniprot id: A0A8C5LII5
names: Subcellular Location Annotation
messages: Membrane

51337:Hdac3
gene id: 51337:Hdac3
uniprot id: A0A8C5JZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

51337:Eif4e1b
gene id: 51337:Eif4e1b
uniprot id: A0A8C5P165
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

51337:Inha
gene id: 51337:Inha
uniprot id: A0A8C5L135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

51337:Actn1
gene id: 51337:Actn1
uniprot id: A0A8C5K9E1
uniprot id: A0A8C5NX06
names: Similarity
messages: Belongs to the alpha-actinin family.

51337:Ackr3
gene id: 51337:Ackr3
uniprot id: A0A8C5K154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Slitrk4
gene id: 51337:Slitrk4
uniprot id: A0A8C5NZB6
names: Similarity
messages: Belongs to the SLITRK family.

51337:Trim65
gene id: 51337:Trim65
uniprot id: A0A8C5NX32
names: Subcellular Location Annotation
messages: Cytoplasm

51337:Med9
gene id: 51337:Med9
uniprot id: A0A8C5LC29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

51337:Ccr2
gene id: 51337:Ccr2
uniprot id: A0A8C5K0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

51337:Ggt6
gene id: 51337:Ggt6
uniprot id: A0A8C5L116
uniprot id: A0A8C5L2W7
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

51337:Pcyt1b
gene id: 51337:Pcyt1b
uniprot id: A0A8C5L3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
messages: Endoplasmic reticulum

51337:Spsb1
gene id: 51337:Spsb1
uniprot id: A0A8C5KM86
names: Similarity
messages: Belongs to the SPSB family.

51337:Gfod2
gene id: 51337:Gfod2
uniprot id: A0A8C5LAF6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

51337:Dhx15
gene id: 51337:Dhx15
uniprot id: A0A8C5NWU8
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

51337:Sprr1b
gene id: 51337:Sprr1b
uniprot id: A0A8C5K647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornifin (SPRR) family.
messages: Cytoplasm

51337:Galnt13
gene id: 51337:Galnt13
uniprot id: A0A8C5K8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Stk11
gene id: 51337:Stk11
uniprot id: A0A8C5KKS3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

51337:Tmem178a
gene id: 51337:Tmem178a
uniprot id: A0A8C5KZP5
names: Similarity
messages: Belongs to the TMEM178 family.

51337:Mettl3
gene id: 51337:Mettl3
uniprot id: A0A8C5L492
names: Similarity
messages: Belongs to the MT-A70-like family.

51337:Stmn2
gene id: 51337:Stmn2
uniprot id: A0A8C5KJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stathmin family.
messages: Cytoplasm
messages: Membrane
messages: lamellipodium

51337:Nr0b2
gene id: 51337:Nr0b2
uniprot id: A0A8C5KEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

51337:Foxh1
gene id: 51337:Foxh1
uniprot id: A0A8C5K8I1
names: Subcellular Location Annotation
messages: Nucleus

51337:Clrn2
gene id: 51337:Clrn2
uniprot id: A0A8C5NWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

51337:Dnase1
gene id: 51337:Dnase1
uniprot id: A0A8C5KZX3
names: Similarity
messages: Belongs to the DNase I family.

51337:Slc24a2
gene id: 51337:Slc24a2
uniprot id: A0A8C5L7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

51337:Hba1
gene id: 51337:Hba1
uniprot id: A0A8C5NXT4
names: Similarity
messages: Belongs to the globin family.

51337:Ltc4s
gene id: 51337:Ltc4s
uniprot id: A0A8C5L5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

51337:Mrps12
gene id: 51337:Mrps12
uniprot id: A0A8C5KV40
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

51337:Insrr
gene id: 51337:Insrr
uniprot id: A0A8C5LN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

51337:Kcng3
gene id: 51337:Kcng3
uniprot id: A0A8C5KJU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

51337:Ankrd13d
gene id: 51337:Ankrd13d
uniprot id: A0A8C5L4D6
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

51337:Slc5a10
gene id: 51337:Slc5a10
uniprot id: A0A8C5L4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:Appl1
gene id: 51337:Appl1
uniprot id: A0A8C5P167
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

51337:Slc6a14
gene id: 51337:Slc6a14
uniprot id: A0A8C5KUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

51337:Slc41a1
gene id: 51337:Slc41a1
uniprot id: A0A8C5KP96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

51337:Dtd2
gene id: 51337:Dtd2
uniprot id: A0A8C5KNT3
names: Similarity
messages: Belongs to the DTD family.

51337:Gale
gene id: 51337:Gale
uniprot id: A0A8C5K7J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

51337:Hacd4
gene id: 51337:Hacd4
uniprot id: A0A8C5P673
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Npy
gene id: 51337:Npy
uniprot id: A0A8C5JYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

51337:Itga7
gene id: 51337:Itga7
uniprot id: A0A8C5NUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

51337:Ssr3
gene id: 51337:Ssr3
uniprot id: A0A8C5P0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

51337:Ptar1
gene id: 51337:Ptar1
uniprot id: A0A8C5KUE4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

51337:Zfyve27
gene id: 51337:Zfyve27
uniprot id: A0A8C5NVP3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

51337:Fabp1
gene id: 51337:Fabp1
uniprot id: A0A8C5LIB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

51337:Mcts1
gene id: 51337:Mcts1
uniprot id: A0A8C5JXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

51337:Rps25
gene id: 51337:Rps25
uniprot id: A0A8C5P2H5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

51337:Foxl1
gene id: 51337:Foxl1
uniprot id: A0A8C5K3U9
names: Subcellular Location Annotation
messages: Nucleus

51337:Agxt
gene id: 51337:Agxt
uniprot id: A0A8C5KDU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

51337:Cct7
gene id: 51337:Cct7
uniprot id: A0A8C5KN92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

51337:Barx2
gene id: 51337:Barx2
uniprot id: A0A8C5L5U3
names: Subcellular Location Annotation
messages: Nucleus

51337:Mmp8
gene id: 51337:Mmp8
uniprot id: A0A8C5L8E9
names: Similarity
messages: Belongs to the peptidase M10A family.

51337:Igf2
gene id: 51337:Igf2
uniprot id: A0A8C5KHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
messages: Secreted

51337:Cdh5
gene id: 51337:Cdh5
uniprot id: A0A8C5L0X7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

51337:Atg101
gene id: 51337:Atg101
uniprot id: A0A8C5LIB7
names: Similarity
messages: Belongs to the ATG101 family.

51337:Tmem120a
gene id: 51337:Tmem120a
uniprot id: A0A8C5LBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

51337:Elf1
gene id: 51337:Elf1
uniprot id: A0A8C5L0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Gdf2
gene id: 51337:Gdf2
uniprot id: A0A8C5L494
names: Similarity
messages: Belongs to the TGF-beta family.

51337:Pbx1
gene id: 51337:Pbx1
uniprot id: A0A8C5KCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

51337:Mogat2
gene id: 51337:Mogat2
uniprot id: A0A8C5LJ89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Tle3
gene id: 51337:Tle3
uniprot id: A0A8C5L6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

51337:Dxo
gene id: 51337:Dxo
uniprot id: A0A8C5KSN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

51337:Cpd
gene id: 51337:Cpd
uniprot id: A0A8C5K148
names: Similarity
messages: Belongs to the peptidase M14 family.

51337:Pwp2
gene id: 51337:Pwp2
uniprot id: A0A8C5KKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

51337:Coq5
gene id: 51337:Coq5
uniprot id: A0A8C5LAH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

51337:Bnip1
gene id: 51337:Bnip1
uniprot id: A0A8C5KU57
names: Subcellular Location Annotation
messages: Membrane

51337:Clp1
gene id: 51337:Clp1
uniprot id: A0A8C5LIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex, composed of CLP1, TSEN2, TSEN15, TSEN34 and TSEN54. Component of pre-mRNA cleavage complex II (CF-II). Also associates with numerous components of the pre-mRNA cleavage complex I (CF-I/CFIm), including NUDT21, CPSF2, CPSF3, CPSF6 and CPSF7. Interacts with CSTF2 and SYMPK.
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

51337:Galnt18
gene id: 51337:Galnt18
uniprot id: A0A8C5L987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

51337:Efnb1
gene id: 51337:Efnb1
uniprot id: A0A8C5LEV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

51337:Slc5a3
gene id: 51337:Slc5a3
uniprot id: A0A8C5KE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

51337:Pik3r1
gene id: 51337:Pik3r1
uniprot id: A0A8C5P3G8
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

51337:Egr3
gene id: 51337:Egr3
uniprot id: A0A8C5KBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

51337:Lvrn
gene id: 51337:Lvrn
uniprot id: A0A8C5P4P6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

51337:LOC101602033
gene id: 51337:LOC101602033
uniprot id: A0A8C5K7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

51337:Ftsj3
gene id: 51337:Ftsj3
uniprot id: A0A8C5KJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

51337:Ak8
gene id: 51337:Ak8
uniprot id: A0A8C5K0X3
names: Similarity
messages: Belongs to the adenylate kinase family.

51337:Rps6kb2
gene id: 51337:Rps6kb2
uniprot id: A0A8C5KS92
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

51337:Plppr1
gene id: 51337:Plppr1
uniprot id: A0A8C5KM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

51337:Emc10
gene id: 51337:Emc10
uniprot id: A0A8C5K7S9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

51337:Grk1
gene id: 51337:Grk1
uniprot id: A0A8C5NWX5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

51337:Grin1
gene id: 51337:Grin1
uniprot id: A0A8C5L7T3
uniprot id: A0A8C5LBI9
uniprot id: A0A8C5LCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

51337:Dync1i2
gene id: 51337:Dync1i2
uniprot id: A0A8C5LHR7
names: Similarity
messages: Belongs to the dynein intermediate chain family.

51337:Sap30l
gene id: 51337:Sap30l
uniprot id: A0A8C5LG42
names: Similarity
messages: Belongs to the SAP30 family.

51337:Deup1
gene id: 51337:Deup1
uniprot id: A0A8C5JUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

51337:Rom1
gene id: 51337:Rom1
uniprot id: A0A8C5KQB6
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

51337:Paqr6
gene id: 51337:Paqr6
uniprot id: A0A8C5JY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

51337:LOC101615482
gene id: 51337:LOC101615482
uniprot id: A0A8C5L383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

51337:Efnb3
gene id: 51337:Efnb3
uniprot id: A0A8C5KEG5
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

51337:Mme
gene id: 51337:Mme
uniprot id: A0A8C5KNE4
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Membrane

51337:Acot13
gene id: 51337:Acot13
uniprot id: A0A8C5LB35
names: Similarity
messages: Belongs to the thioesterase PaaI family.

51337:Gpr84
gene id: 51337:Gpr84
uniprot id: A0A8C5JZU6
names: Subcellular Location Annotation
messages: Membrane

51337:Wfikkn2
gene id: 51337:Wfikkn2
uniprot id: A0A8C5NVP2
names: Similarity
messages: Belongs to the WFIKKN family.

51337:Ndufb10
gene id: 51337:Ndufb10
uniprot id: A0A8C5NXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

51337:Acat2
gene id: 51337:Acat2
uniprot id: A0A8C5LG38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

51337:Purb
gene id: 51337:Purb
uniprot id: A0A8C5KGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

51337:Poglut2
gene id: 51337:Poglut2
uniprot id: A0A8C5LLP4
names: Similarity
messages: Belongs to the KDELC family.

51337:Dmbx1
gene id: 51337:Dmbx1
uniprot id: A0A8C5K6Y2
names: Subcellular Location Annotation
messages: Nucleus

51337:Gcnt4
gene id: 51337:Gcnt4
uniprot id: A0A8C5K9C8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

51337:Pes1
gene id: 51337:Pes1
uniprot id: A0A8C5JYQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

51337:Kif15
gene id: 51337:Kif15
uniprot id: A0A8C5K885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

51337:LOC101594736
gene id: 51337:LOC101594736
uniprot id: A0A8C5KEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

51337:Tekt1
gene id: 51337:Tekt1
uniprot id: A0A8C5JXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

51337:Dusp5
gene id: 51337:Dusp5
uniprot id: A0A8C5LN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

51337:LOC101603557
gene id: 51337:LOC101603557
uniprot id: A0A8C5KZ12
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

51337:Ahcyl2
gene id: 51337:Ahcyl2
uniprot id: A0A8C5K6A6
uniprot id: A0A8C5NWD0
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

51337:Enpp3
gene id: 51337:Enpp3
uniprot id: A0A8C5L775
names: Subcellular Location Annotation
messages: Secreted

51337:Csf2
gene id: 51337:Csf2
uniprot id: A0A8C5KYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
messages: Secreted

51337:Ppfia1
gene id: 51337:Ppfia1
uniprot id: A0A8C5LMK3
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

51337:Plekha8
gene id: 51337:Plekha8
uniprot id: A0A8C5KJS6
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

51337:Atp6v1c2
gene id: 51337:Atp6v1c2
uniprot id: A0A8C5NXC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

51337:Smdt1
gene id: 51337:Smdt1
uniprot id: A0A8C5KX71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

51337:Psmd8
gene id: 51337:Psmd8
uniprot id: A0A8C5L094
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

51337:Minar2
gene id: 51337:Minar2
uniprot id: A0A8C5JVM7
names: Similarity
messages: Belongs to the MINAR family.

51337:Slc18a2
gene id: 51337:Slc18a2
uniprot id: A0A8C5LH14
names: Subcellular Location Annotation
messages: Membrane

51337:LOC101604681
gene id: 51337:LOC101604681
uniprot id: A0A8C5KLF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

51337:Rab9a
gene id: 51337:Rab9a
uniprot id: A0A8C5K2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane