512763:DC20 RS17430
gene id: 512763:DC20_RS17430
uniprot id: A0A0P0CLC5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

512763:DC20 RS04325
gene id: 512763:DC20_RS04325
uniprot id: A0A0P0CV98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS11490
gene id: 512763:DC20_RS11490
uniprot id: A0A0P0CJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

512763:DC20 RS12115
gene id: 512763:DC20_RS12115
uniprot id: A0A0P0CQC5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

512763:DC20 RS20065
gene id: 512763:DC20_RS20065
uniprot id: A0A0P0CZE4
names: Similarity
messages: Belongs to the methyltransferase superfamily.

512763:DC20 RS02230
gene id: 512763:DC20_RS02230
uniprot id: A0A0P0CUH9
names: Subcellular Location Annotation
messages: Cell inner membrane

512763:DC20 RS07180
gene id: 512763:DC20_RS07180
uniprot id: A0A0P0CU45
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS18620
gene id: 512763:DC20_RS18620
uniprot id: A0A0P0C5Z6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

512763:DC20 RS19970
gene id: 512763:DC20_RS19970
uniprot id: A0A0N7HX23
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS02930
gene id: 512763:DC20_RS02930
uniprot id: A0A0P0CUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

512763:DC20 RS10340
gene id: 512763:DC20_RS10340
uniprot id: A0A0N7HWI0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

512763:DC20 RS01280
gene id: 512763:DC20_RS01280
uniprot id: A0A0P0C8Z9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

512763:DC20 RS16395
gene id: 512763:DC20_RS16395
uniprot id: A0A0P0D184
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

512763:DC20 RS10015
gene id: 512763:DC20_RS10015
uniprot id: A0A0P0CC23
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

512763:DC20 RS01030
gene id: 512763:DC20_RS01030
uniprot id: A0A0P0C776
names: Similarity
messages: Belongs to the fabD family.

512763:DC20 RS08170
gene id: 512763:DC20_RS08170
uniprot id: A0A0P0CUJ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

512763:DC20 RS17945
gene id: 512763:DC20_RS17945
uniprot id: A0A0P0CF62
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS21225
gene id: 512763:DC20_RS21225
uniprot id: A0A0P0D3C7
names: Similarity
messages: Belongs to the peptidase S9C family.

512763:DC20 RS11390
gene id: 512763:DC20_RS11390
uniprot id: A0A0N7HX92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

512763:DC20 RS21065
gene id: 512763:DC20_RS21065
uniprot id: A0A0N7HX45
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

512763:DC20 RS17780
gene id: 512763:DC20_RS17780
uniprot id: A0A0P0D0C3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01850
gene id: 512763:DC20_RS01850
uniprot id: A0A0P0BZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

512763:DC20 RS03975
gene id: 512763:DC20_RS03975
uniprot id: A0A0P0CVA3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

512763:DC20 RS02175
gene id: 512763:DC20_RS02175
uniprot id: A0A0N7HW17
names: Similarity
messages: Belongs to the peptidase M13 family.

512763:DC20 RS14895
gene id: 512763:DC20_RS14895
uniprot id: A0A0P0CXB1
names: Similarity
messages: Belongs to the glutamate synthase family.

512763:DC20 RS10605
gene id: 512763:DC20_RS10605
uniprot id: A0A0P0CIU9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

512763:DC20 RS15405
gene id: 512763:DC20_RS15405
uniprot id: A0A0P0C978
names: Similarity
messages: Belongs to the universal stress protein A family.

512763:DC20 RS05695
gene id: 512763:DC20_RS05695
uniprot id: A0A0P0C5M0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

512763:DC20 RS08655
gene id: 512763:DC20_RS08655
uniprot id: A0A0N7HWE6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

512763:DC20 RS15640
gene id: 512763:DC20_RS15640
uniprot id: A0A0P0C9A4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

512763:DC20 RS12755
gene id: 512763:DC20_RS12755
uniprot id: A0A0P0CD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

512763:DC20 RS10685
gene id: 512763:DC20_RS10685
uniprot id: A0A0P0C7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

512763:DC20 RS03640
gene id: 512763:DC20_RS03640
uniprot id: A0A0P0C124
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

512763:DC20 RS12630
gene id: 512763:DC20_RS12630
uniprot id: A0A0P0C869
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11655
gene id: 512763:DC20_RS11655
uniprot id: A0A0P0CSP1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

512763:DC20 RS16305
gene id: 512763:DC20_RS16305
uniprot id: A0A0P0CXW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS10055
gene id: 512763:DC20_RS10055
uniprot id: A0A0P0C3D2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

512763:DC20 RS06345
gene id: 512763:DC20_RS06345
uniprot id: A0A0P0CNG3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

512763:DC20 RS17925
gene id: 512763:DC20_RS17925
uniprot id: A0A0P0D124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

512763:DC20 RS17020
gene id: 512763:DC20_RS17020
uniprot id: A0A0N7HWW2
names: Similarity
messages: Belongs to the threonine aldolase family.

512763:DC20 RS10690
gene id: 512763:DC20_RS10690
uniprot id: A0A0P0CVJ4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

512763:DC20 RS08490
gene id: 512763:DC20_RS08490
uniprot id: A0A0P0CWM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

512763:DC20 RS07110
gene id: 512763:DC20_RS07110
uniprot id: A0A0P0C647
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

512763:DC20 RS07600
gene id: 512763:DC20_RS07600
uniprot id: A0A0P0CUA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS21050
gene id: 512763:DC20_RS21050
uniprot id: A0A0P0CU14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

512763:DC20 RS15575
gene id: 512763:DC20_RS15575
uniprot id: A0A0P0C994
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

512763:DC20 RS03090
gene id: 512763:DC20_RS03090
uniprot id: A0A0P0C035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

512763:DC20 RS16250
gene id: 512763:DC20_RS16250
uniprot id: A0A0P0C5L5
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01830
gene id: 512763:DC20_RS01830
uniprot id: A0A0P0CUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS11735
gene id: 512763:DC20_RS11735
uniprot id: A0A0P0C392
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

512763:DC20 RS00485
gene id: 512763:DC20_RS00485
uniprot id: A0A0P0C3V0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

512763:DC20 RS11930
gene id: 512763:DC20_RS11930
uniprot id: A0A0N7HWL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS06910
gene id: 512763:DC20_RS06910
uniprot id: A0A0P0C1I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

512763:DC20 RS08440
gene id: 512763:DC20_RS08440
uniprot id: A0A0P0CX69
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

512763:DC20 RS17755
gene id: 512763:DC20_RS17755
uniprot id: A0A0P0CA22
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

512763:DC20 RS07480
gene id: 512763:DC20_RS07480
uniprot id: A0A0P0CWU0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

512763:DC20 RS17420
gene id: 512763:DC20_RS17420
uniprot id: A0A0P0C5F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

512763:DC20 RS19880
gene id: 512763:DC20_RS19880
uniprot id: A0A0P0D1A4
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS17490
gene id: 512763:DC20_RS17490
uniprot id: A0A0N7HXB0
names: Subcellular Location Annotation
messages: Nucleus

512763:DC20 RS18265
gene id: 512763:DC20_RS18265
uniprot id: A0A0P0D0J4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

512763:DC20 RS14795
gene id: 512763:DC20_RS14795
uniprot id: A0A0P0C4D9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

512763:DC20 RS03840
gene id: 512763:DC20_RS03840
uniprot id: A0A0P0CV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

512763:DC20 RS02200
gene id: 512763:DC20_RS02200
uniprot id: A0A0P0C9B5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

512763:DC20 RS08920
gene id: 512763:DC20_RS08920
uniprot id: A0A0P0CXE8
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS08070
gene id: 512763:DC20_RS08070
uniprot id: A0A0P0CHZ1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

512763:DC20 RS16995
gene id: 512763:DC20_RS16995
uniprot id: A0A0P0CL81
names: Similarity
messages: Belongs to the UPF0173 family.

512763:DC20 RS11035
gene id: 512763:DC20_RS11035
uniprot id: A0A0P0CXM4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

512763:DC20 RS18050
gene id: 512763:DC20_RS18050
uniprot id: A0A0P0CV31
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

512763:DC20 RS14340
gene id: 512763:DC20_RS14340
uniprot id: A0A0P0CR75
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

512763:DC20 RS05085
gene id: 512763:DC20_RS05085
uniprot id: A0A0P0C7H6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

512763:DC20 RS02890
gene id: 512763:DC20_RS02890
uniprot id: A0A0P0C9K2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

512763:DC20 RS20325
gene id: 512763:DC20_RS20325
uniprot id: A0A0P0C6L6
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS02035
gene id: 512763:DC20_RS02035
uniprot id: A0A0N7HW14
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS11570
gene id: 512763:DC20_RS11570
uniprot id: A0A0N7HWK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

512763:DC20 RS11635
gene id: 512763:DC20_RS11635
uniprot id: A0A0P0CQ63
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

512763:DC20 RS10385
gene id: 512763:DC20_RS10385
uniprot id: A0A0P0D2N3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

512763:DC20 RS12345
gene id: 512763:DC20_RS12345
uniprot id: A0A0N7HWL9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

512763:DC20 RS08735
gene id: 512763:DC20_RS08735
uniprot id: A0A0P0CP72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS09915
gene id: 512763:DC20_RS09915
uniprot id: A0A0P0CXU0
names: Similarity
messages: Belongs to the manganese catalase family.

512763:DC20 RS11015
gene id: 512763:DC20_RS11015
uniprot id: A0A0P0C7L4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

512763:DC20 RS15235
gene id: 512763:DC20_RS15235
uniprot id: A0A0P0C586
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS18230
gene id: 512763:DC20_RS18230
uniprot id: A0A0N7HWY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

512763:DC20 RS22070
gene id: 512763:DC20_RS22070
uniprot id: A0A0P0CI75
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

512763:DC20 RS08785
gene id: 512763:DC20_RS08785
uniprot id: A0A0P0CBM6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

512763:DC20 RS03635
gene id: 512763:DC20_RS03635
uniprot id: A0A0P0CV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS01410
gene id: 512763:DC20_RS01410
uniprot id: A0A0P0C911
names: Similarity
messages: Belongs to the sterol desaturase family.

512763:DC20 RS12220
gene id: 512763:DC20_RS12220
uniprot id: A0A0P0CY32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

512763:DC20 RS10905
gene id: 512763:DC20_RS10905
uniprot id: A0A0P0CY47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

512763:DC20 RS00140
gene id: 512763:DC20_RS00140
uniprot id: A0A0P0BZ06
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

512763:DC20 RS10050
gene id: 512763:DC20_RS10050
uniprot id: A0A0P0CNS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS06290
gene id: 512763:DC20_RS06290
uniprot id: A0A0P0CQF2
names: Similarity
messages: Belongs to the peptidase S41A family.

512763:DC20 RS09240
gene id: 512763:DC20_RS09240
uniprot id: A0A0P0CBS3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

512763:DC20 RS12230
gene id: 512763:DC20_RS12230
uniprot id: A0A0P0CYK3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS04900
gene id: 512763:DC20_RS04900
uniprot id: A0A0P0CT97
names: Similarity
messages: Belongs to the UPF0758 family.

512763:DC20 RS00030
gene id: 512763:DC20_RS00030
uniprot id: A0A0P0C3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

512763:DC20 RS09710
gene id: 512763:DC20_RS09710
uniprot id: A0A0N7HWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

512763:DC20 RS18055
gene id: 512763:DC20_RS18055
uniprot id: A0A0P0D0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS12995
gene id: 512763:DC20_RS12995
uniprot id: A0A0P0C8B7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

512763:DC20 RS16480
gene id: 512763:DC20_RS16480
uniprot id: A0A0P0CL20
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS17680
gene id: 512763:DC20_RS17680
uniprot id: A0A0N7HWX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS12480
gene id: 512763:DC20_RS12480
uniprot id: A0A0P0C853
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

512763:DC20 RS10510
gene id: 512763:DC20_RS10510
uniprot id: A0A0P0C2U8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

512763:DC20 RS13070
gene id: 512763:DC20_RS13070
uniprot id: A0A0P0C8C6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS11680
gene id: 512763:DC20_RS11680
uniprot id: A0A0P0CJC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

512763:DC20 RS08485
gene id: 512763:DC20_RS08485
uniprot id: A0A0P0CRC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS17555
gene id: 512763:DC20_RS17555
uniprot id: A0A0P0C640
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

512763:DC20 RS17230
gene id: 512763:DC20_RS17230
uniprot id: A0A0P0CY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS12930
gene id: 512763:DC20_RS12930
uniprot id: A0A0P0CQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS16815
gene id: 512763:DC20_RS16815
uniprot id: A0A0P0CUL3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

512763:DC20 RS11885
gene id: 512763:DC20_RS11885
uniprot id: A0A0N7HWL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS09765
gene id: 512763:DC20_RS09765
uniprot id: A0A0P0C391
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

512763:DC20 RS09830
gene id: 512763:DC20_RS09830
uniprot id: A0A0P0CX61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS01000
gene id: 512763:DC20_RS01000
uniprot id: A0A0P0CU40
names: Subcellular Location Annotation
messages: Mitochondrion

512763:DC20 RS09350
gene id: 512763:DC20_RS09350
uniprot id: A0A0P0CXL6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

512763:DC20 RS05620
gene id: 512763:DC20_RS05620
uniprot id: A0A0N7HW85
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

512763:DC20 RS15160
gene id: 512763:DC20_RS15160
uniprot id: A0A0P0CZ82
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS20575
gene id: 512763:DC20_RS20575
uniprot id: A0A0P0CW42
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

512763:DC20 RS01400
gene id: 512763:DC20_RS01400
uniprot id: A0A0P0BZH9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS07895
gene id: 512763:DC20_RS07895
uniprot id: A0A0P0CX01
names: Similarity
messages: Belongs to the AIR synthase family.

512763:DC20 RS04835
gene id: 512763:DC20_RS04835
uniprot id: A0A0N7HW71
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

512763:DC20 RS12160
gene id: 512763:DC20_RS12160
uniprot id: A0A0P0C3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

512763:DC20 RS14755
gene id: 512763:DC20_RS14755
uniprot id: A0A0P0CX87
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS13045
gene id: 512763:DC20_RS13045
uniprot id: A0A0P0CJT4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS02420
gene id: 512763:DC20_RS02420
uniprot id: A0A0N7HW22
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

512763:DC20 RS03655
gene id: 512763:DC20_RS03655
uniprot id: A0A0N7HW47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

512763:DC20 RS17260
gene id: 512763:DC20_RS17260
uniprot id: A0A0P0C5C0
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS04635
gene id: 512763:DC20_RS04635
uniprot id: A0A0P0C581
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

512763:DC20 RS11860
gene id: 512763:DC20_RS11860
uniprot id: A0A0P0C414
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

512763:DC20 RS05220
gene id: 512763:DC20_RS05220
uniprot id: A0A0P0C5F8
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

512763:DC20 RS01845
gene id: 512763:DC20_RS01845
uniprot id: A0A0P0CUD5
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS19910
gene id: 512763:DC20_RS19910
uniprot id: A0A0P0CFY9
names: Similarity
messages: Belongs to the DEAD box helicase family.

512763:DC20 RS21025
gene id: 512763:DC20_RS21025
uniprot id: A0A0N7HX44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS01925
gene id: 512763:DC20_RS01925
uniprot id: A0A0P0CG05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

512763:DC20 RS05280
gene id: 512763:DC20_RS05280
uniprot id: A0A0N7HW79
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

512763:DC20 RS04360
gene id: 512763:DC20_RS04360
uniprot id: A0A0P0CMY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

512763:DC20 RS14665
gene id: 512763:DC20_RS14665
uniprot id: A0A0P0C8M5
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

512763:DC20 RS09720
gene id: 512763:DC20_RS09720
uniprot id: A0A0P0CIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

512763:DC20 RS17605
gene id: 512763:DC20_RS17605
uniprot id: A0A0P0CSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

512763:DC20 RS06895
gene id: 512763:DC20_RS06895
uniprot id: A0A0P0CW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

512763:DC20 RS18390
gene id: 512763:DC20_RS18390
uniprot id: A0A0P0CYP6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

512763:DC20 RS08860
gene id: 512763:DC20_RS08860
uniprot id: A0A0P0CBN5
names: Similarity
messages: Belongs to the UPF0047 family.

512763:DC20 RS09705
gene id: 512763:DC20_RS09705
uniprot id: A0A0P0CXR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

512763:DC20 RS12950
gene id: 512763:DC20_RS12950
uniprot id: A0A0P0CYE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

512763:DC20 RS07445
gene id: 512763:DC20_RS07445
uniprot id: A0A0P0CNS3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

512763:DC20 RS02205
gene id: 512763:DC20_RS02205
uniprot id: A0A0P0CM74
names: Similarity
messages: Belongs to the Nudix hydrolase family.

512763:DC20 RS13845
gene id: 512763:DC20_RS13845
uniprot id: A0A0P0CDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

512763:DC20 RS04640
gene id: 512763:DC20_RS04640
uniprot id: A0A0P0CT68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

512763:DC20 RS04945
gene id: 512763:DC20_RS04945
uniprot id: A0A0P0C0V2
names: Subcellular Location Annotation
messages: Cytoplasm

512763:DC20 RS19760
gene id: 512763:DC20_RS19760
uniprot id: A0A0P0D186
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

512763:DC20 RS06175
gene id: 512763:DC20_RS06175
uniprot id: A0A0P0CW89
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

512763:DC20 RS13940
gene id: 512763:DC20_RS13940
uniprot id: A0A0P0CR13
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS18280
gene id: 512763:DC20_RS18280
uniprot id: A0A0N7HWY7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

512763:DC20 RS15390
gene id: 512763:DC20_RS15390
uniprot id: A0A0P0CKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS09040
gene id: 512763:DC20_RS09040
uniprot id: A0A0P0C6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

512763:DC20 RS03160
gene id: 512763:DC20_RS03160
uniprot id: A0A0P0CUX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

512763:DC20 RS16440
gene id: 512763:DC20_RS16440
uniprot id: A0A0P0CZS4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

512763:DC20 RS18070
gene id: 512763:DC20_RS18070
uniprot id: A0A0P0C5R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

512763:DC20 RS06800
gene id: 512763:DC20_RS06800
uniprot id: A0A0P0CNJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

512763:DC20 RS08605
gene id: 512763:DC20_RS08605
uniprot id: A0A0P0CUQ4
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS12120
gene id: 512763:DC20_RS12120
uniprot id: A0A0P0C808
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

512763:DC20 RS15095
gene id: 512763:DC20_RS15095
uniprot id: A0A0N7HWS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS16435
gene id: 512763:DC20_RS16435
uniprot id: A0A0P0CUG2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

512763:DC20 RS13750
gene id: 512763:DC20_RS13750
uniprot id: A0A0P0CZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS18925
gene id: 512763:DC20_RS18925
uniprot id: A0A0P0CYW7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

512763:DC20 RS13110
gene id: 512763:DC20_RS13110
uniprot id: A0A0P0CYX6
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

512763:DC20 RS08725
gene id: 512763:DC20_RS08725
uniprot id: A0A0P0CI65
names: Similarity
messages: Belongs to the LacAB/RpiB family.

512763:DC20 RS14480
gene id: 512763:DC20_RS14480
uniprot id: A0A0P0CDS3
names: Similarity
messages: Belongs to the SCO1/2 family.

512763:DC20 RS19530
gene id: 512763:DC20_RS19530
uniprot id: A0A0P0D148
names: Similarity
messages: Belongs to the UDPGP type 2 family.

512763:DC20 RS08895
gene id: 512763:DC20_RS08895
uniprot id: A0A0N7HX83
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

512763:DC20 RS12670
gene id: 512763:DC20_RS12670
uniprot id: A0A0P0C3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS13605
gene id: 512763:DC20_RS13605
uniprot id: A0A0P0CZ62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS12715
gene id: 512763:DC20_RS12715
uniprot id: A0A0P0CWE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

512763:DC20 RS11630
gene id: 512763:DC20_RS11630
uniprot id: A0A0P0CCM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

512763:DC20 RS11970
gene id: 512763:DC20_RS11970
uniprot id: A0A0P0C7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

512763:DC20 RS13735
gene id: 512763:DC20_RS13735
uniprot id: A0A0P0CYQ2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

512763:DC20 RS02585
gene id: 512763:DC20_RS02585
uniprot id: A0A0P0CUM9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

512763:DC20 RS16820
gene id: 512763:DC20_RS16820
uniprot id: A0A0N7HWV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

512763:DC20 RS14315
gene id: 512763:DC20_RS14315
uniprot id: A0A0P0CZH2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS15240
gene id: 512763:DC20_RS15240
uniprot id: A0A0P0CZV3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

512763:DC20 RS16275
gene id: 512763:DC20_RS16275
uniprot id: A0A0P0CKY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

512763:DC20 RS12465
gene id: 512763:DC20_RS12465
uniprot id: A0A0P0CJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS11620
gene id: 512763:DC20_RS11620
uniprot id: A0A0P0C375
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

512763:DC20 RS07000
gene id: 512763:DC20_RS07000
uniprot id: A0A0P0CU20
names: Similarity
messages: Belongs to the Skp family.

512763:DC20 RS05740
gene id: 512763:DC20_RS05740
uniprot id: A0A0P0C186
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

512763:DC20 RS17920
gene id: 512763:DC20_RS17920
uniprot id: A0A0P0C690
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

512763:DC20 RS05320
gene id: 512763:DC20_RS05320
uniprot id: A0A0P0C1L2
names: Similarity
messages: Belongs to the hyi family.

512763:DC20 RS09080
gene id: 512763:DC20_RS09080
uniprot id: A0A0P0C285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

512763:DC20 RS13190
gene id: 512763:DC20_RS13190
uniprot id: A0A0N7HWN6
names: Similarity
messages: Belongs to the asparagine synthetase family.

512763:DC20 RS01010
gene id: 512763:DC20_RS01010
uniprot id: A0A0N7HVZ4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

512763:DC20 RS09165
gene id: 512763:DC20_RS09165
uniprot id: A0A0P0CBR5
names: Similarity
messages: Belongs to the peptidase U62 family.

512763:DC20 RS03790
gene id: 512763:DC20_RS03790
uniprot id: A0A0P0C0C9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

512763:DC20 RS09620
gene id: 512763:DC20_RS09620
uniprot id: A0A0P0CRV9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

512763:DC20 RS05270
gene id: 512763:DC20_RS05270
uniprot id: A0A0P0CAF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

512763:DC20 RS05005
gene id: 512763:DC20_RS05005
uniprot id: A0A0N7HW74
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

512763:DC20 RS05485
gene id: 512763:DC20_RS05485
uniprot id: A0A0P0CH04
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

512763:DC20 RS10995
gene id: 512763:DC20_RS10995
uniprot id: A0A0P0CCE9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

512763:DC20 RS14020
gene id: 512763:DC20_RS14020
uniprot id: A0A0P0CWX8
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11795
gene id: 512763:DC20_RS11795
uniprot id: A0A0P0CYF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS13440
gene id: 512763:DC20_RS13440
uniprot id: A0A0P0C3V1
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

512763:DC20 RS17175
gene id: 512763:DC20_RS17175
uniprot id: A0A0P0CUR4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

512763:DC20 RS06280
gene id: 512763:DC20_RS06280
uniprot id: A0A0P0C5T9
names: Similarity
messages: Belongs to the GroES chaperonin family.

512763:DC20 RS03385
gene id: 512763:DC20_RS03385
uniprot id: A0A0P0C4V6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS18395
gene id: 512763:DC20_RS18395
uniprot id: A0A0P0CVA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

512763:DC20 RS20590
gene id: 512763:DC20_RS20590
uniprot id: A0A0P0D218
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS03580
gene id: 512763:DC20_RS03580
uniprot id: A0A0N7HW46
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS03320
gene id: 512763:DC20_RS03320
uniprot id: A0A0P0CMK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

512763:DC20 RS11040
gene id: 512763:DC20_RS11040
uniprot id: A0A0P0C3P5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

512763:DC20 RS10850
gene id: 512763:DC20_RS10850
uniprot id: A0A0P0CPX4
names: Similarity
messages: Belongs to the aldose epimerase family.

512763:DC20 RS11185
gene id: 512763:DC20_RS11185
uniprot id: A0A0P0CXP1
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS13315
gene id: 512763:DC20_RS13315
uniprot id: A0A0P0CJX1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

512763:DC20 RS13030
gene id: 512763:DC20_RS13030
uniprot id: A0A0P0CYW5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

512763:DC20 RS15090
gene id: 512763:DC20_RS15090
uniprot id: A0A0P0C571
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS03270
gene id: 512763:DC20_RS03270
uniprot id: A0A0P0CSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

512763:DC20 RS04310
gene id: 512763:DC20_RS04310
uniprot id: A0A0P0C545
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

512763:DC20 RS12470
gene id: 512763:DC20_RS12470
uniprot id: A0A0P0CD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

512763:DC20 RS03865
gene id: 512763:DC20_RS03865
uniprot id: A0A0P0CGR5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

512763:DC20 RS16390
gene id: 512763:DC20_RS16390
uniprot id: A0A0P0D0C2
names: Similarity
messages: Belongs to the peptidase M17 family.

512763:DC20 RS10750
gene id: 512763:DC20_RS10750
uniprot id: A0A0P0C7I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS17965
gene id: 512763:DC20_RS17965
uniprot id: A0A0P0CA53
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

512763:DC20 RS08995
gene id: 512763:DC20_RS08995
uniprot id: A0A0P0CWU4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

512763:DC20 RS07330
gene id: 512763:DC20_RS07330
uniprot id: A0A0P0CU65
names: Similarity
messages: Belongs to the CarB family.

512763:DC20 RS21355
gene id: 512763:DC20_RS21355
uniprot id: A0A0P0CW14
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS05970
gene id: 512763:DC20_RS05970
uniprot id: A0A0P0C5Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS04670
gene id: 512763:DC20_RS04670
uniprot id: A0A0P0C0R5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

512763:DC20 RS21075
gene id: 512763:DC20_RS21075
uniprot id: A0A0P0D1R6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

512763:DC20 RS12125
gene id: 512763:DC20_RS12125
uniprot id: A0A0P0CW67
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

512763:DC20 RS11180
gene id: 512763:DC20_RS11180
uniprot id: A0A0P0CSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS15940
gene id: 512763:DC20_RS15940
uniprot id: A0A0P0C5H0
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS10130
gene id: 512763:DC20_RS10130
uniprot id: A0A0P0CXW3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

512763:DC20 RS09480
gene id: 512763:DC20_RS09480
uniprot id: A0A0P0C361
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

512763:DC20 RS01590
gene id: 512763:DC20_RS01590
uniprot id: A0A0N7HX57
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

512763:DC20 RS06315
gene id: 512763:DC20_RS06315
uniprot id: A0A0P0C1D2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

512763:DC20 RS05305
gene id: 512763:DC20_RS05305
uniprot id: A0A0P0CQ47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS11665
gene id: 512763:DC20_RS11665
uniprot id: A0A0P0C3X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

512763:DC20 RS18400
gene id: 512763:DC20_RS18400
uniprot id: A0A0P0D0L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

512763:DC20 RS17615
gene id: 512763:DC20_RS17615
uniprot id: A0A0P0CA00
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS12295
gene id: 512763:DC20_RS12295
uniprot id: A0A0N7HX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS11825
gene id: 512763:DC20_RS11825
uniprot id: A0A0N7HWK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

512763:DC20 RS00280
gene id: 512763:DC20_RS00280
uniprot id: A0A0P0CTW7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

512763:DC20 RS01290
gene id: 512763:DC20_RS01290
uniprot id: A0A0N7HVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

512763:DC20 RS02055
gene id: 512763:DC20_RS02055
uniprot id: A0A0P0C999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS02155
gene id: 512763:DC20_RS02155
uniprot id: A0A0P0CUH1
names: Similarity
messages: Belongs to the XseB family.

512763:DC20 RS10185
gene id: 512763:DC20_RS10185
uniprot id: A0A0P0CXB2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS05420
gene id: 512763:DC20_RS05420
uniprot id: A0A0P0C128
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

512763:DC20 RS17630
gene id: 512763:DC20_RS17630
uniprot id: A0A0P0D0A1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

512763:DC20 RS17930
gene id: 512763:DC20_RS17930
uniprot id: A0A0P0C5N0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

512763:DC20 RS14645
gene id: 512763:DC20_RS14645
uniprot id: A0A0P0C522
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS17000
gene id: 512763:DC20_RS17000
uniprot id: A0A0P0CEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

512763:DC20 RS11710
gene id: 512763:DC20_RS11710
uniprot id: A0A0P0CSP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

512763:DC20 RS10680
gene id: 512763:DC20_RS10680
uniprot id: A0A0P0CPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

512763:DC20 RS20625
gene id: 512763:DC20_RS20625
uniprot id: A0A0P0CBC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS18945
gene id: 512763:DC20_RS18945
uniprot id: A0A0P0C6N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS18360
gene id: 512763:DC20_RS18360
uniprot id: A0A0P0C5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS18615
gene id: 512763:DC20_RS18615
uniprot id: A0A0P0D1B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

512763:DC20 RS20555
gene id: 512763:DC20_RS20555
uniprot id: A0A0P0CBB1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

512763:DC20 RS03650
gene id: 512763:DC20_RS03650
uniprot id: A0A0P0CV61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

512763:DC20 RS16640
gene id: 512763:DC20_RS16640
uniprot id: A0A0P0CEN9
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11615
gene id: 512763:DC20_RS11615
uniprot id: A0A0P0CYC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

512763:DC20 RS00715
gene id: 512763:DC20_RS00715
uniprot id: A0A0P0CRN1
names: Similarity
messages: Belongs to the peptidase S66 family.

512763:DC20 RS10610
gene id: 512763:DC20_RS10610
uniprot id: A0A0P0CC99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

512763:DC20 RS08210
gene id: 512763:DC20_RS08210
uniprot id: A0A0P0C208
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS18290
gene id: 512763:DC20_RS18290
uniprot id: A0A0P0C5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

512763:DC20 RS02895
gene id: 512763:DC20_RS02895
uniprot id: A0A0P0CMH1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS16260
gene id: 512763:DC20_RS16260
uniprot id: A0A0N7HWU7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

512763:DC20 RS18590
gene id: 512763:DC20_RS18590
uniprot id: A0A0P0CYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

512763:DC20 RS11770
gene id: 512763:DC20_RS11770
uniprot id: A0A0P0CSQ7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

512763:DC20 RS20050
gene id: 512763:DC20_RS20050
uniprot id: A0A0P0CTM3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

512763:DC20 RS08775
gene id: 512763:DC20_RS08775
uniprot id: A0A0P0C261
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

512763:DC20 RS12225
gene id: 512763:DC20_RS12225
uniprot id: A0A0P0C459
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

512763:DC20 RS06820
gene id: 512763:DC20_RS06820
uniprot id: A0A0P0C7N4
names: Similarity
messages: Belongs to the sigma-54 factor family.

512763:DC20 RS09160
gene id: 512763:DC20_RS09160
uniprot id: A0A0P0CIC3
names: Similarity
messages: Belongs to the peptidase U62 family.

512763:DC20 RS02025
gene id: 512763:DC20_RS02025
uniprot id: A0A0P0CUF3
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS20515
gene id: 512763:DC20_RS20515
uniprot id: A0A0P0C7A2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

512763:DC20 RS02630
gene id: 512763:DC20_RS02630
uniprot id: A0A0N7HW26
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS08435
gene id: 512763:DC20_RS08435
uniprot id: A0A0P0CUS7
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07465
gene id: 512763:DC20_RS07465
uniprot id: A0A0P0CQY4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

512763:DC20 RS01350
gene id: 512763:DC20_RS01350
uniprot id: A0A0P0CLX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

512763:DC20 RS12080
gene id: 512763:DC20_RS12080
uniprot id: A0A0N7HWL4
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

512763:DC20 RS01895
gene id: 512763:DC20_RS01895
uniprot id: A0A0P0CUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

512763:DC20 RS03555
gene id: 512763:DC20_RS03555
uniprot id: A0A0P0C119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

512763:DC20 RS16840
gene id: 512763:DC20_RS16840
uniprot id: A0A0P0C557
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

512763:DC20 RS06650
gene id: 512763:DC20_RS06650
uniprot id: A0A0P0C250
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

512763:DC20 RS07370
gene id: 512763:DC20_RS07370
uniprot id: A0A0P0CB47
names: Similarity
messages: Belongs to the DEAD box helicase family.

512763:DC20 RS01380
gene id: 512763:DC20_RS01380
uniprot id: A0A0N7HW01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

512763:DC20 RS10695
gene id: 512763:DC20_RS10695
uniprot id: A0A0P0CS89
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

512763:DC20 RS20795
gene id: 512763:DC20_RS20795
uniprot id: A0A0P0C7E2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS09060
gene id: 512763:DC20_RS09060
uniprot id: A0A0P0C2Z6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

512763:DC20 RS01770
gene id: 512763:DC20_RS01770
uniprot id: A0A0P0C0C4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

512763:DC20 RS11170
gene id: 512763:DC20_RS11170
uniprot id: A0A0P0CVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS16200
gene id: 512763:DC20_RS16200
uniprot id: A0A0P0D097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

512763:DC20 RS11605
gene id: 512763:DC20_RS11605
uniprot id: A0A0P0C3X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

512763:DC20 RS17970
gene id: 512763:DC20_RS17970
uniprot id: A0A0P0CYI5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

512763:DC20 RS11725
gene id: 512763:DC20_RS11725
uniprot id: A0A0P0CYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

512763:DC20 RS11135
gene id: 512763:DC20_RS11135
uniprot id: A0A0N7HWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS03265
gene id: 512763:DC20_RS03265
uniprot id: A0A0P0C4U5
names: Similarity
messages: Belongs to the IMPACT family.

512763:DC20 RS10495
gene id: 512763:DC20_RS10495
uniprot id: A0A0P0C3I5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

512763:DC20 RS01660
gene id: 512763:DC20_RS01660
uniprot id: A0A0P0CNX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

512763:DC20 RS09220
gene id: 512763:DC20_RS09220
uniprot id: A0A0P0C2B0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS10560
gene id: 512763:DC20_RS10560
uniprot id: A0A0P0CVH6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

512763:DC20 RS08240
gene id: 512763:DC20_RS08240
uniprot id: A0A0P0CUK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

512763:DC20 RS03275
gene id: 512763:DC20_RS03275
uniprot id: A0A0P0CPF3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

512763:DC20 RS14395
gene id: 512763:DC20_RS14395
uniprot id: A0A0P0C487
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

512763:DC20 RS16230
gene id: 512763:DC20_RS16230
uniprot id: A0A0P0C9H7
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

512763:DC20 RS14675
gene id: 512763:DC20_RS14675
uniprot id: A0A0P0CRE3
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS03795
gene id: 512763:DC20_RS03795
uniprot id: A0A0N7HW50
names: Subcellular Location Annotation
messages: Cytoplasm

512763:DC20 RS16790
gene id: 512763:DC20_RS16790
uniprot id: A0A0P0CER1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

512763:DC20 RS16280
gene id: 512763:DC20_RS16280
uniprot id: A0A0N7HXA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

512763:DC20 RS06135
gene id: 512763:DC20_RS06135
uniprot id: A0A0P0CAQ2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS15085
gene id: 512763:DC20_RS15085
uniprot id: A0A0P0CZ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

512763:DC20 RS18585
gene id: 512763:DC20_RS18585
uniprot id: A0A0P0CAE4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

512763:DC20 RS05955
gene id: 512763:DC20_RS05955
uniprot id: A0A0P0CAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS00460
gene id: 512763:DC20_RS00460
uniprot id: A0A0P0C8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

512763:DC20 RS15330
gene id: 512763:DC20_RS15330
uniprot id: A0A0P0CRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS08040
gene id: 512763:DC20_RS08040
uniprot id: A0A0P0C2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS07500
gene id: 512763:DC20_RS07500
uniprot id: A0A0N7HWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

512763:DC20 RS16620
gene id: 512763:DC20_RS16620
uniprot id: A0A0N7HWV4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

512763:DC20 RS13805
gene id: 512763:DC20_RS13805
uniprot id: A0A0P0CYR0
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS21405
gene id: 512763:DC20_RS21405
uniprot id: A0A0P0D1H9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS16905
gene id: 512763:DC20_RS16905
uniprot id: A0A0P0D0K5
names: Similarity
messages: Belongs to the peptidase C40 family.

512763:DC20 RS06935
gene id: 512763:DC20_RS06935
uniprot id: A0A0P0C620
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

512763:DC20 RS16365
gene id: 512763:DC20_RS16365
uniprot id: A0A0P0C9J2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

512763:DC20 RS11355
gene id: 512763:DC20_RS11355
uniprot id: A0A0P0CQ31
names: Similarity
messages: Belongs to the YciI family.

512763:DC20 RS05045
gene id: 512763:DC20_RS05045
uniprot id: A0A0P0CN43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

512763:DC20 RS04415
gene id: 512763:DC20_RS04415
uniprot id: A0A0P0C1A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

512763:DC20 RS02800
gene id: 512763:DC20_RS02800
uniprot id: A0A0P0BZZ2
names: Similarity
messages: Belongs to the DprA/Smf family.

512763:DC20 RS14200
gene id: 512763:DC20_RS14200
uniprot id: A0A0N7HWQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

512763:DC20 RS10490
gene id: 512763:DC20_RS10490
uniprot id: A0A0P0CXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

512763:DC20 RS15280
gene id: 512763:DC20_RS15280
uniprot id: A0A0P0CXG3
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS11505
gene id: 512763:DC20_RS11505
uniprot id: A0A0P0C7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

512763:DC20 RS17370
gene id: 512763:DC20_RS17370
uniprot id: A0A0N7HWW9
names: Similarity
messages: Belongs to the pyruvate kinase family.

512763:DC20 RS15200
gene id: 512763:DC20_RS15200
uniprot id: A0A0N7HWS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS13020
gene id: 512763:DC20_RS13020
uniprot id: A0A0P0CYF9
names: Similarity
messages: Belongs to the pyruvate kinase family.

512763:DC20 RS21085
gene id: 512763:DC20_RS21085
uniprot id: A0A0P0D282
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

512763:DC20 RS18675
gene id: 512763:DC20_RS18675
uniprot id: A0A0P0D0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

512763:DC20 RS07800
gene id: 512763:DC20_RS07800
uniprot id: A0A0N7HWC9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

512763:DC20 RS03150
gene id: 512763:DC20_RS03150
uniprot id: A0A0P0CUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

512763:DC20 RS11625
gene id: 512763:DC20_RS11625
uniprot id: A0A0P0CJB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

512763:DC20 RS09800
gene id: 512763:DC20_RS09800
uniprot id: A0A0P0CCD5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

512763:DC20 RS18820
gene id: 512763:DC20_RS18820
uniprot id: A0A0P0CLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

512763:DC20 RS16950
gene id: 512763:DC20_RS16950
uniprot id: A0A0P0CY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

512763:DC20 RS18980
gene id: 512763:DC20_RS18980
uniprot id: A0A0P0CT45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS12135
gene id: 512763:DC20_RS12135
uniprot id: A0A0P0CSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

512763:DC20 RS21115
gene id: 512763:DC20_RS21115
uniprot id: A0A0P0CBJ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

512763:DC20 RS07490
gene id: 512763:DC20_RS07490
uniprot id: A0A0P0CHR7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

512763:DC20 RS12240
gene id: 512763:DC20_RS12240
uniprot id: A0A0N7HWL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

512763:DC20 RS06185
gene id: 512763:DC20_RS06185
uniprot id: A0A0P0CHC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

512763:DC20 RS05975
gene id: 512763:DC20_RS05975
uniprot id: A0A0N7HW92
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

512763:DC20 RS06535
gene id: 512763:DC20_RS06535
uniprot id: A0A0P0C1F1
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS11270
gene id: 512763:DC20_RS11270
uniprot id: A0A0P0C334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS20505
gene id: 512763:DC20_RS20505
uniprot id: A0A0P0CW31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

512763:DC20 RS16470
gene id: 512763:DC20_RS16470
uniprot id: A0A0P0C521
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

512763:DC20 RS19985
gene id: 512763:DC20_RS19985
uniprot id: A0A0P0CB32
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

512763:DC20 RS18005
gene id: 512763:DC20_RS18005
uniprot id: A0A0P0D134
names: Similarity
messages: Belongs to the DNA photolyase family.

512763:DC20 RS08700
gene id: 512763:DC20_RS08700
uniprot id: A0A0P0C2W1
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS16970
gene id: 512763:DC20_RS16970
uniprot id: A0A0N7HWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

512763:DC20 RS18515
gene id: 512763:DC20_RS18515
uniprot id: A0A0N7HWZ2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

512763:DC20 RS21190
gene id: 512763:DC20_RS21190
uniprot id: A0A0P0CBK2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

512763:DC20 RS01875
gene id: 512763:DC20_RS01875
uniprot id: A0A0P0CM31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

512763:DC20 RS05380
gene id: 512763:DC20_RS05380
uniprot id: A0A0P0CVM7
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS14530
gene id: 512763:DC20_RS14530
uniprot id: A0A0P0C4A8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

512763:DC20 RS15785
gene id: 512763:DC20_RS15785
uniprot id: A0A0N7HWT7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

512763:DC20 RS00635
gene id: 512763:DC20_RS00635
uniprot id: A0A0N7HVY8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

512763:DC20 RS18410
gene id: 512763:DC20_RS18410
uniprot id: A0A0P0D196
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

512763:DC20 RS11585
gene id: 512763:DC20_RS11585
uniprot id: A0A0P0C7T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

512763:DC20 RS12990
gene id: 512763:DC20_RS12990
uniprot id: A0A0P0CQN8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

512763:DC20 RS16935
gene id: 512763:DC20_RS16935
uniprot id: A0A0P0CET3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

512763:DC20 RS17485
gene id: 512763:DC20_RS17485
uniprot id: A0A0P0C631
names: Similarity
messages: Belongs to the FPG family.

512763:DC20 RS04355
gene id: 512763:DC20_RS04355
uniprot id: A0A0P0CA38
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

512763:DC20 RS10300
gene id: 512763:DC20_RS10300
uniprot id: A0A0P0CVE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

512763:DC20 RS02410
gene id: 512763:DC20_RS02410
uniprot id: A0A0P0CMA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS15615
gene id: 512763:DC20_RS15615
uniprot id: A0A0P0D012
names: Similarity
messages: Belongs to the universal stress protein A family.

512763:DC20 RS10880
gene id: 512763:DC20_RS10880
uniprot id: A0A0P0CVM2
names: Similarity
messages: Belongs to the aldose epimerase family.

512763:DC20 RS08355
gene id: 512763:DC20_RS08355
uniprot id: A0A0P0CX56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

512763:DC20 RS07440
gene id: 512763:DC20_RS07440
uniprot id: A0A0P0CB55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

512763:DC20 RS04230
gene id: 512763:DC20_RS04230
uniprot id: A0A0N7HX65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

512763:DC20 RS06475
gene id: 512763:DC20_RS06475
uniprot id: A0A0P0CHG2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

512763:DC20 RS16730
gene id: 512763:DC20_RS16730
uniprot id: A0A0P0CSA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

512763:DC20 RS06975
gene id: 512763:DC20_RS06975
uniprot id: A0A0P0CHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

512763:DC20 RS03175
gene id: 512763:DC20_RS03175
uniprot id: A0A0P0CGI4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

512763:DC20 RS05700
gene id: 512763:DC20_RS05700
uniprot id: A0A0P0CTK5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

512763:DC20 RS11575
gene id: 512763:DC20_RS11575
uniprot id: A0A0P0CCL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

512763:DC20 RS19390
gene id: 512763:DC20_RS19390
uniprot id: A0A0P0CAU4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

512763:DC20 RS01395
gene id: 512763:DC20_RS01395
uniprot id: A0A0P0CU87
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

512763:DC20 RS04755
gene id: 512763:DC20_RS04755
uniprot id: A0A0N7HW69
names: Similarity
messages: Belongs to the CvfB family.

512763:DC20 RS16425
gene id: 512763:DC20_RS16425
uniprot id: A0A0P0C9K4
names: Similarity
messages: Belongs to the group II decarboxylase family.

512763:DC20 RS11560
gene id: 512763:DC20_RS11560
uniprot id: A0A0P0C368
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

512763:DC20 RS08585
gene id: 512763:DC20_RS08585
uniprot id: A0A0P0CI54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

512763:DC20 RS04235
gene id: 512763:DC20_RS04235
uniprot id: A0A0P0CWN8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

512763:DC20 RS18965
gene id: 512763:DC20_RS18965
uniprot id: A0A0P0CPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS16075
gene id: 512763:DC20_RS16075
uniprot id: A0A0P0C4V3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07210
gene id: 512763:DC20_RS07210
uniprot id: A0A0P0CWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

512763:DC20 RS20070
gene id: 512763:DC20_RS20070
uniprot id: A0A0N7HX25
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS17185
gene id: 512763:DC20_RS17185
uniprot id: A0A0P0C5Z7
names: Similarity
messages: Belongs to the DEAD box helicase family.

512763:DC20 RS01820
gene id: 512763:DC20_RS01820
uniprot id: A0A0P0CRY6
names: Similarity
messages: Belongs to the SCO1/2 family.

512763:DC20 RS05470
gene id: 512763:DC20_RS05470
uniprot id: A0A0P0CNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

512763:DC20 RS13620
gene id: 512763:DC20_RS13620
uniprot id: A0A0P0CDG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS01135
gene id: 512763:DC20_RS01135
uniprot id: A0A0P0CRR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

512763:DC20 RS04535
gene id: 512763:DC20_RS04535
uniprot id: A0A0P0C0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

512763:DC20 RS12765
gene id: 512763:DC20_RS12765
uniprot id: A0A0P0CQL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

512763:DC20 RS05110
gene id: 512763:DC20_RS05110
uniprot id: A0A0P0CAD9
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

512763:DC20 RS12350
gene id: 512763:DC20_RS12350
uniprot id: A0A0P0C835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

512763:DC20 RS03315
gene id: 512763:DC20_RS03315
uniprot id: A0A0P0C9R0
names: Similarity
messages: Belongs to the ComB family.

512763:DC20 RS21925
gene id: 512763:DC20_RS21925
uniprot id: A0A0P0CDE2
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

512763:DC20 RS00465
gene id: 512763:DC20_RS00465
uniprot id: A0A0P0CLM7
names: Subcellular Location Annotation
messages: Cytoplasm

512763:DC20 RS02190
gene id: 512763:DC20_RS02190
uniprot id: A0A0P0CG45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

512763:DC20 RS13795
gene id: 512763:DC20_RS13795
uniprot id: A0A0P0CTC6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

512763:DC20 RS06170
gene id: 512763:DC20_RS06170
uniprot id: A0A0P0C1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS12385
gene id: 512763:DC20_RS12385
uniprot id: A0A0P0CYL5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

512763:DC20 RS11480
gene id: 512763:DC20_RS11480
uniprot id: A0A0P0CYB6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS12705
gene id: 512763:DC20_RS12705
uniprot id: A0A0P0C877
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

512763:DC20 RS13785
gene id: 512763:DC20_RS13785
uniprot id: A0A0P0CWT6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

512763:DC20 RS01480
gene id: 512763:DC20_RS01480
uniprot id: A0A0P0CLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

512763:DC20 RS11540
gene id: 512763:DC20_RS11540
uniprot id: A0A0P0CXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

512763:DC20 RS13895
gene id: 512763:DC20_RS13895
uniprot id: A0A0P0CXD3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

512763:DC20 RS16350
gene id: 512763:DC20_RS16350
uniprot id: A0A0P0CEJ1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

512763:DC20 RS18380
gene id: 512763:DC20_RS18380
uniprot id: A0A0N7HWY9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

512763:DC20 RS03630
gene id: 512763:DC20_RS03630
uniprot id: A0A0P0CPI4
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS08185
gene id: 512763:DC20_RS08185
uniprot id: A0A0P0CWJ0
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS00705
gene id: 512763:DC20_RS00705
uniprot id: A0A0N7HVY9
names: Similarity
messages: Belongs to the peptidase S33 family.

512763:DC20 RS18710
gene id: 512763:DC20_RS18710
uniprot id: A0A0P0CT08
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS15470
gene id: 512763:DC20_RS15470
uniprot id: A0A0P0D3I6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

512763:DC20 RS17005
gene id: 512763:DC20_RS17005
uniprot id: A0A0P0CSD5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS04680
gene id: 512763:DC20_RS04680
uniprot id: A0A0P0CA83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

512763:DC20 RS08770
gene id: 512763:DC20_RS08770
uniprot id: A0A0P0CXD5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

512763:DC20 RS05095
gene id: 512763:DC20_RS05095
uniprot id: A0A0P0CVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

512763:DC20 RS03245
gene id: 512763:DC20_RS03245
uniprot id: A0A0P0C9Q1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

512763:DC20 RS13690
gene id: 512763:DC20_RS13690
uniprot id: A0A0P0CDH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

512763:DC20 RS17470
gene id: 512763:DC20_RS17470
uniprot id: A0A0P0CUV5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

512763:DC20 RS18790
gene id: 512763:DC20_RS18790
uniprot id: A0A0P0CVD6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS13675
gene id: 512763:DC20_RS13675
uniprot id: A0A0P0CZ73
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

512763:DC20 RS10345
gene id: 512763:DC20_RS10345
uniprot id: A0A0P0CIS3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

512763:DC20 RS14060
gene id: 512763:DC20_RS14060
uniprot id: A0A0P0CDL9
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01460
gene id: 512763:DC20_RS01460
uniprot id: A0A0P0BZI7
names: Similarity
messages: Belongs to the asparagine synthetase family.

512763:DC20 RS10740
gene id: 512763:DC20_RS10740
uniprot id: A0A0P0CPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

512763:DC20 RS17125
gene id: 512763:DC20_RS17125
uniprot id: A0A0P0C5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

512763:DC20 RS00065
gene id: 512763:DC20_RS00065
uniprot id: A0A0P0CTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

512763:DC20 RS17545
gene id: 512763:DC20_RS17545
uniprot id: A0A0P0CUW9
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

512763:DC20 RS11460
gene id: 512763:DC20_RS11460
uniprot id: A0A0P0CSL9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

512763:DC20 RS21315
gene id: 512763:DC20_RS21315
uniprot id: A0A0P0CU46
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS06730
gene id: 512763:DC20_RS06730
uniprot id: A0A0P0CQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

512763:DC20 RS07270
gene id: 512763:DC20_RS07270
uniprot id: A0A0P0CW68
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS03195
gene id: 512763:DC20_RS03195
uniprot id: A0A0P0C4U0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

512763:DC20 RS00275
gene id: 512763:DC20_RS00275
uniprot id: A0A0P0CNJ6
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS16375
gene id: 512763:DC20_RS16375
uniprot id: A0A0P0CUE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

512763:DC20 RS02345
gene id: 512763:DC20_RS02345
uniprot id: A0A0P0C4H4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS10140
gene id: 512763:DC20_RS10140
uniprot id: A0A0P0CIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS02615
gene id: 512763:DC20_RS02615
uniprot id: A0A0P0BZW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

512763:DC20 RS05500
gene id: 512763:DC20_RS05500
uniprot id: A0A0P0C138
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

512763:DC20 RS00545
gene id: 512763:DC20_RS00545
uniprot id: A0A0P0C8T0
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

512763:DC20 RS06995
gene id: 512763:DC20_RS06995
uniprot id: A0A0N7HWB2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

512763:DC20 RS06100
gene id: 512763:DC20_RS06100
uniprot id: A0A0N7HW94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS13960
gene id: 512763:DC20_RS13960
uniprot id: A0A0P0CYS2
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS07510
gene id: 512763:DC20_RS07510
uniprot id: A0A0P0CNT2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

512763:DC20 RS18540
gene id: 512763:DC20_RS18540
uniprot id: A0A0P0C6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

512763:DC20 RS06205
gene id: 512763:DC20_RS06205
uniprot id: A0A0P0C5S8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

512763:DC20 RS13610
gene id: 512763:DC20_RS13610
uniprot id: A0A0P0C3X3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

512763:DC20 RS10035
gene id: 512763:DC20_RS10035
uniprot id: A0A0P0CVA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS01415
gene id: 512763:DC20_RS01415
uniprot id: A0A0P0CLY5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

512763:DC20 RS02990
gene id: 512763:DC20_RS02990
uniprot id: A0A0P0C4R2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

512763:DC20 RS04285
gene id: 512763:DC20_RS04285
uniprot id: A0A0P0CGW0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

512763:DC20 RS11940
gene id: 512763:DC20_RS11940
uniprot id: A0A0P0CYH1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

512763:DC20 RS17140
gene id: 512763:DC20_RS17140
uniprot id: A0A0P0CSF2
names: Similarity
messages: Belongs to the threonine synthase family.

512763:DC20 RS15865
gene id: 512763:DC20_RS15865
uniprot id: A0A0P0C5F5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

512763:DC20 RS01330
gene id: 512763:DC20_RS01330
uniprot id: A0A0N7HW00
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS08230
gene id: 512763:DC20_RS08230
uniprot id: A0A0P0C6K9
names: Similarity
messages: Belongs to the RutC family.

512763:DC20 RS11610
gene id: 512763:DC20_RS11610
uniprot id: A0A0N7HWK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

512763:DC20 RS12850
gene id: 512763:DC20_RS12850
uniprot id: A0A0P0CT16
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

512763:DC20 RS11055
gene id: 512763:DC20_RS11055
uniprot id: A0A0P0CY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

512763:DC20 RS07650
gene id: 512763:DC20_RS07650
uniprot id: A0A0N7HWC6
names: Similarity
messages: Belongs to the NusB family.

512763:DC20 RS18730
gene id: 512763:DC20_RS18730
uniprot id: A0A0P0D0R4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

512763:DC20 RS14080
gene id: 512763:DC20_RS14080
uniprot id: A0A0P0CWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

512763:DC20 RS11230
gene id: 512763:DC20_RS11230
uniprot id: A0A0P0CQ12
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

512763:DC20 RS01640
gene id: 512763:DC20_RS01640
uniprot id: A0A0N7HW06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS07620
gene id: 512763:DC20_RS07620
uniprot id: A0A0P0C2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

512763:DC20 RS17735
gene id: 512763:DC20_RS17735
uniprot id: A0A0P0CLG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS19610
gene id: 512763:DC20_RS19610
uniprot id: A0A0P0D1P0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

512763:DC20 RS12770
gene id: 512763:DC20_RS12770
uniprot id: A0A0P0C885
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

512763:DC20 RS09895
gene id: 512763:DC20_RS09895
uniprot id: A0A0P0CRZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

512763:DC20 RS05765
gene id: 512763:DC20_RS05765
uniprot id: A0A0P0C5N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

512763:DC20 RS16485
gene id: 512763:DC20_RS16485
uniprot id: A0A0P0C8S4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS09055
gene id: 512763:DC20_RS09055
uniprot id: A0A0P0CWV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

512763:DC20 RS02650
gene id: 512763:DC20_RS02650
uniprot id: A0A0P0CBV0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

512763:DC20 RS11760
gene id: 512763:DC20_RS11760
uniprot id: A0A0P0CW18
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

512763:DC20 RS02020
gene id: 512763:DC20_RS02020
uniprot id: A0A0P0CP09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

512763:DC20 RS02375
gene id: 512763:DC20_RS02375
uniprot id: A0A0N7HW21
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07790
gene id: 512763:DC20_RS07790
uniprot id: A0A0P0D0N2
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS14820
gene id: 512763:DC20_RS14820
uniprot id: A0A0N7HWR9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

512763:DC20 RS09730
gene id: 512763:DC20_RS09730
uniprot id: A0A0P0CPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

512763:DC20 RS12625
gene id: 512763:DC20_RS12625
uniprot id: A0A0P0CXB4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

512763:DC20 RS18705
gene id: 512763:DC20_RS18705
uniprot id: A0A0N7HWZ6
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

512763:DC20 RS05190
gene id: 512763:DC20_RS05190
uniprot id: A0A0P0CH59
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

512763:DC20 RS06195
gene id: 512763:DC20_RS06195
uniprot id: A0A0N7HW96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

512763:DC20 RS17530
gene id: 512763:DC20_RS17530
uniprot id: A0A0P0C9Z2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS01525
gene id: 512763:DC20_RS01525
uniprot id: A0A0N7HW04
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

512763:DC20 RS18165
gene id: 512763:DC20_RS18165
uniprot id: A0A0P0CF94
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

512763:DC20 RS04210
gene id: 512763:DC20_RS04210
uniprot id: A0A0P0CMW5
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

512763:DC20 RS11520
gene id: 512763:DC20_RS11520
uniprot id: A0A0P0CSM6
names: Similarity
messages: Belongs to the peptidase M1 family.

512763:DC20 RS05260
gene id: 512763:DC20_RS05260
uniprot id: A0A0P0C106
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

512763:DC20 RS10190
gene id: 512763:DC20_RS10190
uniprot id: A0A0P0C3E7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

512763:DC20 RS09090
gene id: 512763:DC20_RS09090
uniprot id: A0A0P0CBQ8
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

512763:DC20 RS03065
gene id: 512763:DC20_RS03065
uniprot id: A0A0P0CPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

512763:DC20 RS06855
gene id: 512763:DC20_RS06855
uniprot id: A0A0P0CAX7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

512763:DC20 RS07685
gene id: 512763:DC20_RS07685
uniprot id: A0A0P0CWC3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11175
gene id: 512763:DC20_RS11175
uniprot id: A0A0N7HWJ5
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS06320
gene id: 512763:DC20_RS06320
uniprot id: A0A0P0CUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

512763:DC20 RS05440
gene id: 512763:DC20_RS05440
uniprot id: A0A0P0CN69
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

512763:DC20 RS16800
gene id: 512763:DC20_RS16800
uniprot id: A0A0P0C9P9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

512763:DC20 RS10005
gene id: 512763:DC20_RS10005
uniprot id: A0A0P0CIP3
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

512763:DC20 RS04475
gene id: 512763:DC20_RS04475
uniprot id: A0A0P0CA51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

512763:DC20 RS01485
gene id: 512763:DC20_RS01485
uniprot id: A0A0P0C443
names: Similarity
messages: Belongs to the peptidase S49 family.

512763:DC20 RS00525
gene id: 512763:DC20_RS00525
uniprot id: A0A0P0C013
names: Similarity
messages: Belongs to the peptidase S58 family.

512763:DC20 RS18600
gene id: 512763:DC20_RS18600
uniprot id: A0A0P0D0P7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

512763:DC20 RS12955
gene id: 512763:DC20_RS12955
uniprot id: A0A0N7HWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

512763:DC20 RS06180
gene id: 512763:DC20_RS06180
uniprot id: A0A0P0C1C0
names: Similarity
messages: Belongs to the BshC family.

512763:DC20 RS03500
gene id: 512763:DC20_RS03500
uniprot id: A0A0P0CV35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

512763:DC20 RS10980
gene id: 512763:DC20_RS10980
uniprot id: A0A0P0C304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

512763:DC20 RS18750
gene id: 512763:DC20_RS18750
uniprot id: A0A0P0C612
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS06805
gene id: 512763:DC20_RS06805
uniprot id: A0A0P0C603
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

512763:DC20 RS19565
gene id: 512763:DC20_RS19565
uniprot id: A0A0P0CFU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

512763:DC20 RS16360
gene id: 512763:DC20_RS16360
uniprot id: A0A0N7HWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

512763:DC20 RS12365
gene id: 512763:DC20_RS12365
uniprot id: A0A0P0CSW4
names: Similarity
messages: Belongs to the peptidase M24B family.

512763:DC20 RS04845
gene id: 512763:DC20_RS04845
uniprot id: A0A0P0D276
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

512763:DC20 RS13725
gene id: 512763:DC20_RS13725
uniprot id: A0A0P0CTB9
names: Similarity
messages: Belongs to the glycosyl hydrolase.

512763:DC20 RS02440
gene id: 512763:DC20_RS02440
uniprot id: A0A0P0CUL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

512763:DC20 RS04405
gene id: 512763:DC20_RS04405
uniprot id: A0A0P0CVA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS06850
gene id: 512763:DC20_RS06850
uniprot id: A0A0P0CHJ4
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

512763:DC20 RS08400
gene id: 512763:DC20_RS08400
uniprot id: A0A0P0CUL4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS16510
gene id: 512763:DC20_RS16510
uniprot id: A0A0N7HWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

512763:DC20 RS19850
gene id: 512763:DC20_RS19850
uniprot id: A0A0P0CFX9
names: Similarity
messages: Belongs to the citrate synthase family.

512763:DC20 RS21030
gene id: 512763:DC20_RS21030
uniprot id: A0A0P0D272
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS01900
gene id: 512763:DC20_RS01900
uniprot id: A0A0N7HW11
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

512763:DC20 RS08460
gene id: 512763:DC20_RS08460
uniprot id: A0A0P0CP45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

512763:DC20 RS11740
gene id: 512763:DC20_RS11740
uniprot id: A0A0P0CJE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

512763:DC20 RS13105
gene id: 512763:DC20_RS13105
uniprot id: A0A0N7HWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

512763:DC20 RS01890
gene id: 512763:DC20_RS01890
uniprot id: A0A0P0CNZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

512763:DC20 RS14650
gene id: 512763:DC20_RS14650
uniprot id: A0A0P0CZM5
names: Similarity
messages: Belongs to the DinB family.

512763:DC20 RS04695
gene id: 512763:DC20_RS04695
uniprot id: A0A0P0CT75
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS13340
gene id: 512763:DC20_RS13340
uniprot id: A0A0P0C8G2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

512763:DC20 RS10165
gene id: 512763:DC20_RS10165
uniprot id: A0A0P0CVD0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

512763:DC20 RS04720
gene id: 512763:DC20_RS04720
uniprot id: A0A0P0CVK5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

512763:DC20 RS18335
gene id: 512763:DC20_RS18335
uniprot id: A0A0P0D0K2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS17785
gene id: 512763:DC20_RS17785
uniprot id: A0A0P0C669
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01170
gene id: 512763:DC20_RS01170
uniprot id: A0A0P0CU54
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

512763:DC20 RS02090
gene id: 512763:DC20_RS02090
uniprot id: A0A0P0C0I2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS04505
gene id: 512763:DC20_RS04505
uniprot id: A0A0N7HX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

512763:DC20 RS15080
gene id: 512763:DC20_RS15080
uniprot id: A0A0P0CTV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

512763:DC20 RS14015
gene id: 512763:DC20_RS14015
uniprot id: A0A0N7HWQ2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01535
gene id: 512763:DC20_RS01535
uniprot id: A0A0P0CUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

512763:DC20 RS20465
gene id: 512763:DC20_RS20465
uniprot id: A0A0P0C6N5
names: Similarity
messages: Belongs to the asparaginase 1 family.

512763:DC20 RS20645
gene id: 512763:DC20_RS20645
uniprot id: A0A0P0C7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

512763:DC20 RS06925
gene id: 512763:DC20_RS06925
uniprot id: A0A0P0CAY6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

512763:DC20 RS11095
gene id: 512763:DC20_RS11095
uniprot id: A0A0P0CPZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

512763:DC20 RS08730
gene id: 512763:DC20_RS08730
uniprot id: A0A0P0CBL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

512763:DC20 RS04120
gene id: 512763:DC20_RS04120
uniprot id: A0A0N7HW57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

512763:DC20 RS05645
gene id: 512763:DC20_RS05645
uniprot id: A0A0P0CW01
names: Similarity
messages: Belongs to the peptidase C56 family.

512763:DC20 RS13430
gene id: 512763:DC20_RS13430
uniprot id: A0A0P0C4L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

512763:DC20 RS12825
gene id: 512763:DC20_RS12825
uniprot id: A0A0P0CQM4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

512763:DC20 RS02330
gene id: 512763:DC20_RS02330
uniprot id: A0A0P0C9D2
names: Similarity
messages: Belongs to the group II decarboxylase family.

512763:DC20 RS05550
gene id: 512763:DC20_RS05550
uniprot id: A0A0P0CVP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

512763:DC20 RS13000
gene id: 512763:DC20_RS13000
uniprot id: A0A0N7HWN2
names: Similarity
messages: Belongs to the GARS family.

512763:DC20 RS01755
gene id: 512763:DC20_RS01755
uniprot id: A0A0P0CGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

512763:DC20 RS10705
gene id: 512763:DC20_RS10705
uniprot id: A0A0P0C3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

512763:DC20 RS18950
gene id: 512763:DC20_RS18950
uniprot id: A0A0P0C8D8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

512763:DC20 RS04785
gene id: 512763:DC20_RS04785
uniprot id: A0A0P0CVL1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

512763:DC20 RS02275
gene id: 512763:DC20_RS02275
uniprot id: A0A0P0CS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS05980
gene id: 512763:DC20_RS05980
uniprot id: A0A0P0CC37
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS16205
gene id: 512763:DC20_RS16205
uniprot id: A0A0P0C4X2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

512763:DC20 RS09670
gene id: 512763:DC20_RS09670
uniprot id: A0A0P0CPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

512763:DC20 RS14370
gene id: 512763:DC20_RS14370
uniprot id: A0A0P0CTJ7
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07015
gene id: 512763:DC20_RS07015
uniprot id: A0A0P0CW44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

512763:DC20 RS22050
gene id: 512763:DC20_RS22050
uniprot id: A0A0P0C8W6
names: Similarity
messages: Belongs to the RuBisCO large chain family.

512763:DC20 RS11600
gene id: 512763:DC20_RS11600
uniprot id: A0A0P0CXV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

512763:DC20 RS03470
gene id: 512763:DC20_RS03470
uniprot id: A0A0P0CST1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

512763:DC20 RS17085
gene id: 512763:DC20_RS17085
uniprot id: A0A0P0C9T7
names: Similarity
messages: Belongs to the peptidase C40 family.

512763:DC20 RS13965
gene id: 512763:DC20_RS13965
uniprot id: A0A0N7HWQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS04960
gene id: 512763:DC20_RS04960
uniprot id: A0A0P0CAC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

512763:DC20 RS02050
gene id: 512763:DC20_RS02050
uniprot id: A0A0P0CG23
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

512763:DC20 RS21045
gene id: 512763:DC20_RS21045
uniprot id: A0A0P0CGF7
names: Similarity
messages: Belongs to the aspartokinase family.

512763:DC20 RS07410
gene id: 512763:DC20_RS07410
uniprot id: A0A0N7HWC1
names: Similarity
messages: Belongs to the peptidase S66 family.

512763:DC20 RS12590
gene id: 512763:DC20_RS12590
uniprot id: A0A0P0CYP2
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

512763:DC20 RS03780
gene id: 512763:DC20_RS03780
uniprot id: A0A0P0CV77
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

512763:DC20 RS01720
gene id: 512763:DC20_RS01720
uniprot id: A0A0P0C955
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

512763:DC20 RS10835
gene id: 512763:DC20_RS10835
uniprot id: A0A0P0CJ15
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

512763:DC20 RS02040
gene id: 512763:DC20_RS02040
uniprot id: A0A0P0CUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS13585
gene id: 512763:DC20_RS13585
uniprot id: A0A0P0CTA6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

512763:DC20 RS15115
gene id: 512763:DC20_RS15115
uniprot id: A0A0P0CE08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

512763:DC20 RS15100
gene id: 512763:DC20_RS15100
uniprot id: A0A0P0CZT1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

512763:DC20 RS07220
gene id: 512763:DC20_RS07220
uniprot id: A0A0P0C1M0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

512763:DC20 RS18595
gene id: 512763:DC20_RS18595
uniprot id: A0A0P0CVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

512763:DC20 RS04215
gene id: 512763:DC20_RS04215
uniprot id: A0A0N7HW59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

512763:DC20 RS08580
gene id: 512763:DC20_RS08580
uniprot id: A0A0P0C244
names: Similarity
messages: Belongs to the DinB family.

512763:DC20 RS17500
gene id: 512763:DC20_RS17500
uniprot id: A0A0P0C5H4
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

512763:DC20 RS06245
gene id: 512763:DC20_RS06245
uniprot id: A0A0P0CW97
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

512763:DC20 RS10670
gene id: 512763:DC20_RS10670
uniprot id: A0A0P0CCB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

512763:DC20 RS01725
gene id: 512763:DC20_RS01725
uniprot id: A0A0P0CM15
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

512763:DC20 RS18610
gene id: 512763:DC20_RS18610
uniprot id: A0A0N7HWZ4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

512763:DC20 RS17445
gene id: 512763:DC20_RS17445
uniprot id: A0A0P0CSJ4
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS20735
gene id: 512763:DC20_RS20735
uniprot id: A0A0P0CGB0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

512763:DC20 RS03005
gene id: 512763:DC20_RS03005
uniprot id: A0A0P0CUT2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

512763:DC20 RS21130
gene id: 512763:DC20_RS21130
uniprot id: A0A0P0CD44
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS21480
gene id: 512763:DC20_RS21480
uniprot id: A0A0N7HXC2
names: Similarity
messages: Belongs to the DapA family.

512763:DC20 RS18775
gene id: 512763:DC20_RS18775
uniprot id: A0A0P0CT17
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

512763:DC20 RS11145
gene id: 512763:DC20_RS11145
uniprot id: A0A0P0C318
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS07350
gene id: 512763:DC20_RS07350
uniprot id: A0A0P0CWS2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11670
gene id: 512763:DC20_RS11670
uniprot id: A0A0P0CYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

512763:DC20 RS12540
gene id: 512763:DC20_RS12540
uniprot id: A0A0N7HWM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS00105
gene id: 512763:DC20_RS00105
uniprot id: A0A0P0CN23
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS06480
gene id: 512763:DC20_RS06480
uniprot id: A0A0P0CAT7
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS12050
gene id: 512763:DC20_RS12050
uniprot id: A0A0P0C7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

512763:DC20 RS13305
gene id: 512763:DC20_RS13305
uniprot id: A0A0P0CZ14
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

512763:DC20 RS01740
gene id: 512763:DC20_RS01740
uniprot id: A0A0P0CRX6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

512763:DC20 RS10250
gene id: 512763:DC20_RS10250
uniprot id: A0A0P0CXB8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS21345
gene id: 512763:DC20_RS21345
uniprot id: A0A0P0C7L9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

512763:DC20 RS17345
gene id: 512763:DC20_RS17345
uniprot id: A0A0P0CEY9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS06690
gene id: 512763:DC20_RS06690
uniprot id: A0A0P0CAW2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

512763:DC20 RS21485
gene id: 512763:DC20_RS21485
uniprot id: A0A0P0D1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

512763:DC20 RS15890
gene id: 512763:DC20_RS15890
uniprot id: A0A0P0CEB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS17030
gene id: 512763:DC20_RS17030
uniprot id: A0A0P0CUP9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

512763:DC20 RS17505
gene id: 512763:DC20_RS17505
uniprot id: A0A0P0CP74
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

512763:DC20 RS19755
gene id: 512763:DC20_RS19755
uniprot id: A0A0N7HX18
names: Subcellular Location Annotation
messages: Cytoplasm

512763:DC20 RS17400
gene id: 512763:DC20_RS17400
uniprot id: A0A0P0D068
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS18715
gene id: 512763:DC20_RS18715
uniprot id: A0A0P0CAG5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

512763:DC20 RS02960
gene id: 512763:DC20_RS02960
uniprot id: A0A0P0C010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

512763:DC20 RS11550
gene id: 512763:DC20_RS11550
uniprot id: A0A0P0C3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

512763:DC20 RS06945
gene id: 512763:DC20_RS06945
uniprot id: A0A0P0CQP8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

512763:DC20 RS13935
gene id: 512763:DC20_RS13935
uniprot id: A0A0P0CDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS19705
gene id: 512763:DC20_RS19705
uniprot id: A0A0P0C6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS17250
gene id: 512763:DC20_RS17250
uniprot id: A0A0P0D0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS01325
gene id: 512763:DC20_RS01325
uniprot id: A0A0P0BZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

512763:DC20 RS03220
gene id: 512763:DC20_RS03220
uniprot id: A0A0P0C0X2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

512763:DC20 RS07495
gene id: 512763:DC20_RS07495
uniprot id: A0A0P0C7P4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

512763:DC20 RS05950
gene id: 512763:DC20_RS05950
uniprot id: A0A0P0CHB2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS08195
gene id: 512763:DC20_RS08195
uniprot id: A0A0P0CC90
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

512763:DC20 RS13035
gene id: 512763:DC20_RS13035
uniprot id: A0A0P0C3P2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

512763:DC20 RS10135
gene id: 512763:DC20_RS10135
uniprot id: A0A0P0C2P7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

512763:DC20 RS04715
gene id: 512763:DC20_RS04715
uniprot id: A0A0P0C1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

512763:DC20 RS04955
gene id: 512763:DC20_RS04955
uniprot id: A0A0N7HW73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

512763:DC20 RS12910
gene id: 512763:DC20_RS12910
uniprot id: A0A0N7HWN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

512763:DC20 RS19980
gene id: 512763:DC20_RS19980
uniprot id: A0A0P0CTL6
names: Similarity
messages: Belongs to the peptidase S8 family.

512763:DC20 RS08370
gene id: 512763:DC20_RS08370
uniprot id: A0A0N7HWE0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

512763:DC20 RS11850
gene id: 512763:DC20_RS11850
uniprot id: A0A0P0CSR5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

512763:DC20 RS11700
gene id: 512763:DC20_RS11700
uniprot id: A0A0P0C7V1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

512763:DC20 RS03750
gene id: 512763:DC20_RS03750
uniprot id: A0A0P0D241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

512763:DC20 RS18635
gene id: 512763:DC20_RS18635
uniprot id: A0A0P0CSZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

512763:DC20 RS09580
gene id: 512763:DC20_RS09580
uniprot id: A0A0P0CIJ3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS03335
gene id: 512763:DC20_RS03335
uniprot id: A0A0P0CPG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

512763:DC20 RS12395
gene id: 512763:DC20_RS12395
uniprot id: A0A0N7HWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

512763:DC20 RS08340
gene id: 512763:DC20_RS08340
uniprot id: A0A0P0CRA2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

512763:DC20 RS01685
gene id: 512763:DC20_RS01685
uniprot id: A0A0P0BZK8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

512763:DC20 RS06045
gene id: 512763:DC20_RS06045
uniprot id: A0A0P0CAP2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

512763:DC20 RS20710
gene id: 512763:DC20_RS20710
uniprot id: A0A0P0C7D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

512763:DC20 RS08970
gene id: 512763:DC20_RS08970
uniprot id: A0A0N7HWF2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS17665
gene id: 512763:DC20_RS17665
uniprot id: A0A0P0CSL8
names: Similarity
messages: Belongs to the WrbA family.

512763:DC20 RS17110
gene id: 512763:DC20_RS17110
uniprot id: A0A0P0C5Z0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS01645
gene id: 512763:DC20_RS01645
uniprot id: A0A0P0CM07
names: Similarity
messages: Belongs to the arginase family.

512763:DC20 RS07875
gene id: 512763:DC20_RS07875
uniprot id: A0A0P0CR45
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS08525
gene id: 512763:DC20_RS08525
uniprot id: A0A0P0CBI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

512763:DC20 RS18250
gene id: 512763:DC20_RS18250
uniprot id: A0A0P0CYM3
names: Similarity
messages: Belongs to the DprA/Smf family.

512763:DC20 RS04160
gene id: 512763:DC20_RS04160
uniprot id: A0A0N7HW58
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

512763:DC20 RS18175
gene id: 512763:DC20_RS18175
uniprot id: A0A0P0CA86
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

512763:DC20 RS10940
gene id: 512763:DC20_RS10940
uniprot id: A0A0P0C7K6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

512763:DC20 RS17065
gene id: 512763:DC20_RS17065
uniprot id: A0A0P0CL88
names: Similarity
messages: Belongs to the peptidase M1 family.

512763:DC20 RS16400
gene id: 512763:DC20_RS16400
uniprot id: A0A0P0C505
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

512763:DC20 RS07455
gene id: 512763:DC20_RS07455
uniprot id: A0A0N7HWC2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

512763:DC20 RS04950
gene id: 512763:DC20_RS04950
uniprot id: A0A0P0CH44
names: Similarity
messages: Belongs to the Dps family.

512763:DC20 RS13790
gene id: 512763:DC20_RS13790
uniprot id: A0A0P0CHH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

512763:DC20 RS12270
gene id: 512763:DC20_RS12270
uniprot id: A0A0P0C829
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS16110
gene id: 512763:DC20_RS16110
uniprot id: A0A0P0CXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS17900
gene id: 512763:DC20_RS17900
uniprot id: A0A0P0CA45
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

512763:DC20 RS17705
gene id: 512763:DC20_RS17705
uniprot id: A0A0P0D0B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

512763:DC20 RS17520
gene id: 512763:DC20_RS17520
uniprot id: A0A0P0CF06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

512763:DC20 RS13325
gene id: 512763:DC20_RS13325
uniprot id: A0A0P0CQU0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

512763:DC20 RS12040
gene id: 512763:DC20_RS12040
uniprot id: A0A0P0CCV3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

512763:DC20 RS20895
gene id: 512763:DC20_RS20895
uniprot id: A0A0P0C6U6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

512763:DC20 RS10875
gene id: 512763:DC20_RS10875
uniprot id: A0A0P0C7J6
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS04295
gene id: 512763:DC20_RS04295
uniprot id: A0A0P0D2P2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01310
gene id: 512763:DC20_RS01310
uniprot id: A0A0P0CU69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS21785
gene id: 512763:DC20_RS21785
uniprot id: A0A0P0D1N8
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

512763:DC20 RS06750
gene id: 512763:DC20_RS06750
uniprot id: A0A0P0CWH0
names: Similarity
messages: Belongs to the DSD1 family.

512763:DC20 RS05195
gene id: 512763:DC20_RS05195
uniprot id: A0A0P0CAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS10170
gene id: 512763:DC20_RS10170
uniprot id: A0A0P0CUX1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

512763:DC20 RS03055
gene id: 512763:DC20_RS03055
uniprot id: A0A0P0CSI3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

512763:DC20 RS20760
gene id: 512763:DC20_RS20760
uniprot id: A0A0N7HX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

512763:DC20 RS15795
gene id: 512763:DC20_RS15795
uniprot id: A0A0P0C4R6
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

512763:DC20 RS02875
gene id: 512763:DC20_RS02875
uniprot id: A0A0P0CUR8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

512763:DC20 RS12210
gene id: 512763:DC20_RS12210
uniprot id: A0A0P0CW79
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

512763:DC20 RS02380
gene id: 512763:DC20_RS02380
uniprot id: A0A0P0C0L5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

512763:DC20 RS13625
gene id: 512763:DC20_RS13625
uniprot id: A0A0P0CQX7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

512763:DC20 RS01305
gene id: 512763:DC20_RS01305
uniprot id: A0A0P0CNT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

512763:DC20 RS17830
gene id: 512763:DC20_RS17830
uniprot id: A0A0P0CSN7
names: Similarity
messages: Belongs to the glutamine synthetase family.

512763:DC20 RS00150
gene id: 512763:DC20_RS00150
uniprot id: A0A0P0CFE9
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS03940
gene id: 512763:DC20_RS03940
uniprot id: A0A0P0CMQ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

512763:DC20 RS16595
gene id: 512763:DC20_RS16595
uniprot id: A0A0P0C9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

512763:DC20 RS15395
gene id: 512763:DC20_RS15395
uniprot id: A0A0P0CE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS10195
gene id: 512763:DC20_RS10195
uniprot id: A0A0P0CXX2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

512763:DC20 RS21300
gene id: 512763:DC20_RS21300
uniprot id: A0A0P0CN10
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS04910
gene id: 512763:DC20_RS04910
uniprot id: A0A0P0CNE6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

512763:DC20 RS18655
gene id: 512763:DC20_RS18655
uniprot id: A0A0N7HWZ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS20155
gene id: 512763:DC20_RS20155
uniprot id: A0A0P0CZF5
names: Similarity
messages: Belongs to the nitroreductase family.

512763:DC20 RS07100
gene id: 512763:DC20_RS07100
uniprot id: A0A0P0CB11
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

512763:DC20 RS14905
gene id: 512763:DC20_RS14905
uniprot id: A0A0P0CZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

512763:DC20 RS20365
gene id: 512763:DC20_RS20365
uniprot id: A0A0P0CW03
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

512763:DC20 RS15820
gene id: 512763:DC20_RS15820
uniprot id: A0A0P0D319
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

512763:DC20 RS04540
gene id: 512763:DC20_RS04540
uniprot id: A0A0P0CGZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

512763:DC20 RS16795
gene id: 512763:DC20_RS16795
uniprot id: A0A0P0CSB4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

512763:DC20 RS06875
gene id: 512763:DC20_RS06875
uniprot id: A0A0P0C614
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS18745
gene id: 512763:DC20_RS18745
uniprot id: A0A0N7HWZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

512763:DC20 RS04515
gene id: 512763:DC20_RS04515
uniprot id: A0A0N7HW64
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS10100
gene id: 512763:DC20_RS10100
uniprot id: A0A0P0CVC3
names: Similarity
messages: Belongs to the arginase family.

512763:DC20 RS04940
gene id: 512763:DC20_RS04940
uniprot id: A0A0P0CUH6
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

512763:DC20 RS17675
gene id: 512763:DC20_RS17675
uniprot id: A0A0P0CYF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

512763:DC20 RS08830
gene id: 512763:DC20_RS08830
uniprot id: A0A0P0C2X4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS19575
gene id: 512763:DC20_RS19575
uniprot id: A0A0P0CTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

512763:DC20 RS12640
gene id: 512763:DC20_RS12640
uniprot id: A0A0P0CWD9
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS04660
gene id: 512763:DC20_RS04660
uniprot id: A0A0P0CVK0
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

512763:DC20 RS20230
gene id: 512763:DC20_RS20230
uniprot id: A0A0P0CVY6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

512763:DC20 RS20440
gene id: 512763:DC20_RS20440
uniprot id: A0A0P0C794
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

512763:DC20 RS02350
gene id: 512763:DC20_RS02350
uniprot id: A0A0P0CS63
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

512763:DC20 RS04345
gene id: 512763:DC20_RS04345
uniprot id: A0A0P0C0K1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

512763:DC20 RS03835
gene id: 512763:DC20_RS03835
uniprot id: A0A0P0C7D8
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

512763:DC20 RS09715
gene id: 512763:DC20_RS09715
uniprot id: A0A0P0C2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

512763:DC20 RS09805
gene id: 512763:DC20_RS09805
uniprot id: A0A0N7HWG9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

512763:DC20 RS12495
gene id: 512763:DC20_RS12495
uniprot id: A0A0P0CWC0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS02965
gene id: 512763:DC20_RS02965
uniprot id: A0A0P0CGF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS09900
gene id: 512763:DC20_RS09900
uniprot id: A0A0P0CX70
names: Subunit
messages: Monomer.

512763:DC20 RS18200
gene id: 512763:DC20_RS18200
uniprot id: A0A0P0C6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

512763:DC20 RS03685
gene id: 512763:DC20_RS03685
uniprot id: A0A0P0CSV5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

512763:DC20 RS01185
gene id: 512763:DC20_RS01185
uniprot id: A0A0N7HVZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS04780
gene id: 512763:DC20_RS04780
uniprot id: A0A0P0C1F0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

512763:DC20 RS11720
gene id: 512763:DC20_RS11720
uniprot id: A0A0P0C3Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

512763:DC20 RS20335
gene id: 512763:DC20_RS20335
uniprot id: A0A0P0CMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

512763:DC20 RS13800
gene id: 512763:DC20_RS13800
uniprot id: A0A0N7HWP8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

512763:DC20 RS14130
gene id: 512763:DC20_RS14130
uniprot id: A0A0P0CR41
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS10305
gene id: 512763:DC20_RS10305
uniprot id: A0A0P0CS46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

512763:DC20 RS07655
gene id: 512763:DC20_RS07655
uniprot id: A0A0P0CNU5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

512763:DC20 RS04605
gene id: 512763:DC20_RS04605
uniprot id: A0A0P0C0P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

512763:DC20 RS12835
gene id: 512763:DC20_RS12835
uniprot id: A0A0P0C896
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

512763:DC20 RS05245
gene id: 512763:DC20_RS05245
uniprot id: A0A0P0CVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Secreted

512763:DC20 RS20630
gene id: 512763:DC20_RS20630
uniprot id: A0A0P0CZM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS15220
gene id: 512763:DC20_RS15220
uniprot id: A0A0P0CTW9
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

512763:DC20 RS01345
gene id: 512763:DC20_RS01345
uniprot id: A0A0P0C904
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

512763:DC20 RS07120
gene id: 512763:DC20_RS07120
uniprot id: A0A0N7HWB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

512763:DC20 RS02555
gene id: 512763:DC20_RS02555
uniprot id: A0A0P0CMC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS19830
gene id: 512763:DC20_RS19830
uniprot id: A0A0P0D1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS16315
gene id: 512763:DC20_RS16315
uniprot id: A0A0N7HWU8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

512763:DC20 RS18700
gene id: 512763:DC20_RS18700
uniprot id: A0A0P0CFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS02620
gene id: 512763:DC20_RS02620
uniprot id: A0A0P0CGA0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

512763:DC20 RS06970
gene id: 512763:DC20_RS06970
uniprot id: A0A0P0C1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

512763:DC20 RS01125
gene id: 512763:DC20_RS01125
uniprot id: A0A0P0CLV4
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS06070
gene id: 512763:DC20_RS06070
uniprot id: A0A0P0CQD1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

512763:DC20 RS11565
gene id: 512763:DC20_RS11565
uniprot id: A0A0P0CJA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

512763:DC20 RS16655
gene id: 512763:DC20_RS16655
uniprot id: A0A0P0C9N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

512763:DC20 RS01855
gene id: 512763:DC20_RS01855
uniprot id: A0A0N7HW10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

512763:DC20 RS10085
gene id: 512763:DC20_RS10085
uniprot id: A0A0P0CC32
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

512763:DC20 RS11375
gene id: 512763:DC20_RS11375
uniprot id: A0A0P0CSI2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

512763:DC20 RS21080
gene id: 512763:DC20_RS21080
uniprot id: A0A0P0C7I2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

512763:DC20 RS07540
gene id: 512763:DC20_RS07540
uniprot id: A0A0P0CWA3
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

512763:DC20 RS00735
gene id: 512763:DC20_RS00735
uniprot id: A0A0P0CU12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

512763:DC20 RS20560
gene id: 512763:DC20_RS20560
uniprot id: A0A0P0CZL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

512763:DC20 RS03145
gene id: 512763:DC20_RS03145
uniprot id: A0A0P0CPE1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

512763:DC20 RS08850
gene id: 512763:DC20_RS08850
uniprot id: A0A0N7HWF0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

512763:DC20 RS04315
gene id: 512763:DC20_RS04315
uniprot id: A0A0P0CT38
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS18850
gene id: 512763:DC20_RS18850
uniprot id: A0A0P0CAI7
names: Similarity
messages: Belongs to the type IB topoisomerase family.

512763:DC20 RS03695
gene id: 512763:DC20_RS03695
uniprot id: A0A0N7HW48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

512763:DC20 RS16740
gene id: 512763:DC20_RS16740
uniprot id: A0A0P0CY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

512763:DC20 RS06635
gene id: 512763:DC20_RS06635
uniprot id: A0A0N7HWA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

512763:DC20 RS14170
gene id: 512763:DC20_RS14170
uniprot id: A0A0P0C4V7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

512763:DC20 RS16450
gene id: 512763:DC20_RS16450
uniprot id: A0A0P0CXI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

512763:DC20 RS16975
gene id: 512763:DC20_RS16975
uniprot id: A0A0P0C5X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

512763:DC20 RS19400
gene id: 512763:DC20_RS19400
uniprot id: A0A0P0CVM1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

512763:DC20 RS20530
gene id: 512763:DC20_RS20530
uniprot id: A0A0P0C6P5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

512763:DC20 RS03755
gene id: 512763:DC20_RS03755
uniprot id: A0A0P0CSW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

512763:DC20 RS10820
gene id: 512763:DC20_RS10820
uniprot id: A0A0P0CY38
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

512763:DC20 RS11745
gene id: 512763:DC20_RS11745
uniprot id: A0A0P0CCQ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

512763:DC20 RS10825
gene id: 512763:DC20_RS10825
uniprot id: A0A0P0C2Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS11715
gene id: 512763:DC20_RS11715
uniprot id: A0A0P0CXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

512763:DC20 RS10225
gene id: 512763:DC20_RS10225
uniprot id: A0A0P0C7C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

512763:DC20 RS08405
gene id: 512763:DC20_RS08405
uniprot id: A0A0P0CRB2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

512763:DC20 RS21335
gene id: 512763:DC20_RS21335
uniprot id: A0A0P0D1V2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS18960
gene id: 512763:DC20_RS18960
uniprot id: A0A0P0C646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS15365
gene id: 512763:DC20_RS15365
uniprot id: A0A0P0CZA9
names: Similarity
messages: Belongs to the UxaA family.

512763:DC20 RS08870
gene id: 512763:DC20_RS08870
uniprot id: A0A0P0CP91
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

512763:DC20 RS08540
gene id: 512763:DC20_RS08540
uniprot id: A0A0P0C6P4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

512763:DC20 RS09975
gene id: 512763:DC20_RS09975
uniprot id: A0A0P0C3C2
names: Similarity
messages: Belongs to the Vsr family.

512763:DC20 RS09315
gene id: 512763:DC20_RS09315
uniprot id: A0A0P0CPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS11225
gene id: 512763:DC20_RS11225
uniprot id: A0A0N7HWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

512763:DC20 RS02510
gene id: 512763:DC20_RS02510
uniprot id: A0A0P0CS98
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

512763:DC20 RS12610
gene id: 512763:DC20_RS12610
uniprot id: A0A0P0CD22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

512763:DC20 RS05565
gene id: 512763:DC20_RS05565
uniprot id: A0A0P0CVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

512763:DC20 RS15920
gene id: 512763:DC20_RS15920
uniprot id: A0A0P0D3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

512763:DC20 RS14505
gene id: 512763:DC20_RS14505
uniprot id: A0A0P0CX45
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01540
gene id: 512763:DC20_RS01540
uniprot id: A0A0P0BZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

512763:DC20 RS02645
gene id: 512763:DC20_RS02645
uniprot id: A0A0P0CSC1
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS08415
gene id: 512763:DC20_RS08415
uniprot id: A0A0P0CWL3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS10315
gene id: 512763:DC20_RS10315
uniprot id: A0A0P0D0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

512763:DC20 RS03125
gene id: 512763:DC20_RS03125
uniprot id: A0A0N7HW36
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS12490
gene id: 512763:DC20_RS12490
uniprot id: A0A0N7HWM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

512763:DC20 RS04020
gene id: 512763:DC20_RS04020
uniprot id: A0A0P0CSZ5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

512763:DC20 RS00415
gene id: 512763:DC20_RS00415
uniprot id: A0A0P0CNK3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS15535
gene id: 512763:DC20_RS15535
uniprot id: A0A0P0CZD2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

512763:DC20 RS06825
gene id: 512763:DC20_RS06825
uniprot id: A0A0N7HWA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS16745
gene id: 512763:DC20_RS16745
uniprot id: A0A0P0CUK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS15385
gene id: 512763:DC20_RS15385
uniprot id: A0A0N7HWT0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS11245
gene id: 512763:DC20_RS11245
uniprot id: A0A0P0CSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

512763:DC20 RS15215
gene id: 512763:DC20_RS15215
uniprot id: A0A0P0CXF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

512763:DC20 RS10580
gene id: 512763:DC20_RS10580
uniprot id: A0A0P0CXG6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS04375
gene id: 512763:DC20_RS04375
uniprot id: A0A0P0CT46
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS18780
gene id: 512763:DC20_RS18780
uniprot id: A0A0P0CAH6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

512763:DC20 RS12425
gene id: 512763:DC20_RS12425
uniprot id: A0A0P0CSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

512763:DC20 RS14990
gene id: 512763:DC20_RS14990
uniprot id: A0A0P0CZ57
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

512763:DC20 RS14910
gene id: 512763:DC20_RS14910
uniprot id: A0A0N7HWS1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

512763:DC20 RS04575
gene id: 512763:DC20_RS04575
uniprot id: A0A0N7HW65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS20120
gene id: 512763:DC20_RS20120
uniprot id: A0A0P0CME7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

512763:DC20 RS11690
gene id: 512763:DC20_RS11690
uniprot id: A0A0N7HWK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

512763:DC20 RS13510
gene id: 512763:DC20_RS13510
uniprot id: A0A0P0C4M4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS14275
gene id: 512763:DC20_RS14275
uniprot id: A0A0P0CDP8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

512763:DC20 RS11750
gene id: 512763:DC20_RS11750
uniprot id: A0A0P0CQ72
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

512763:DC20 RS16965
gene id: 512763:DC20_RS16965
uniprot id: A0A0P0D004
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

512763:DC20 RS01425
gene id: 512763:DC20_RS01425
uniprot id: A0A0N7HW02
names: Similarity
messages: Belongs to the thioredoxin family.

512763:DC20 RS11215
gene id: 512763:DC20_RS11215
uniprot id: A0A0P0CJ60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

512763:DC20 RS13830
gene id: 512763:DC20_RS13830
uniprot id: A0A0N7HX99
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

512763:DC20 RS14175
gene id: 512763:DC20_RS14175
uniprot id: A0A0P0CZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS05635
gene id: 512763:DC20_RS05635
uniprot id: A0A0P0CWU2
names: Similarity
messages: Belongs to the histone deacetylase family.

512763:DC20 RS11495
gene id: 512763:DC20_RS11495
uniprot id: A0A0P0CCK8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

512763:DC20 RS16235
gene id: 512763:DC20_RS16235
uniprot id: A0A0P0CXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

512763:DC20 RS06565
gene id: 512763:DC20_RS06565
uniprot id: A0A0P0C5X6
names: Similarity
messages: Belongs to the YciI family.

512763:DC20 RS18605
gene id: 512763:DC20_RS18605
uniprot id: A0A0P0C6J0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS14685
gene id: 512763:DC20_RS14685
uniprot id: A0A0P0D3G8
names: Similarity
messages: Belongs to the peptidase S9C family.

512763:DC20 RS06965
gene id: 512763:DC20_RS06965
uniprot id: A0A0P0CWJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

512763:DC20 RS16370
gene id: 512763:DC20_RS16370
uniprot id: A0A0P0CXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

512763:DC20 RS17190
gene id: 512763:DC20_RS17190
uniprot id: A0A0P0D0Q7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS19550
gene id: 512763:DC20_RS19550
uniprot id: A0A0P0D1N6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS09340
gene id: 512763:DC20_RS09340
uniprot id: A0A0P0CWZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

512763:DC20 RS20000
gene id: 512763:DC20_RS20000
uniprot id: A0A0P0CVW3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

512763:DC20 RS08815
gene id: 512763:DC20_RS08815
uniprot id: A0A0P0D324
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

512763:DC20 RS04850
gene id: 512763:DC20_RS04850
uniprot id: A0A0P0CVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

512763:DC20 RS13005
gene id: 512763:DC20_RS13005
uniprot id: A0A0P0CWI6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

512763:DC20 RS04095
gene id: 512763:DC20_RS04095
uniprot id: A0A0P0CPM6
names: Similarity
messages: Belongs to the Nth/MutY family.

512763:DC20 RS09865
gene id: 512763:DC20_RS09865
uniprot id: A0A0P0D2M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

512763:DC20 RS13560
gene id: 512763:DC20_RS13560
uniprot id: A0A0P0CQW9
names: Similarity
messages: Belongs to the peptidase M24B family.

512763:DC20 RS20300
gene id: 512763:DC20_RS20300
uniprot id: A0A0P0CZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

512763:DC20 RS04370
gene id: 512763:DC20_RS04370
uniprot id: A0A0N7HW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS16540
gene id: 512763:DC20_RS16540
uniprot id: A0A0P0C895
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS00980
gene id: 512763:DC20_RS00980
uniprot id: A0A0N7HX54
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07125
gene id: 512763:DC20_RS07125
uniprot id: A0A0P0CQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

512763:DC20 RS08680
gene id: 512763:DC20_RS08680
uniprot id: A0A0P0CUR2
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01230
gene id: 512763:DC20_RS01230
uniprot id: A0A0P0CRS7
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS03345
gene id: 512763:DC20_RS03345
uniprot id: A0A0N7HW41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS06240
gene id: 512763:DC20_RS06240
uniprot id: A0A0P0C1W9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS11685
gene id: 512763:DC20_RS11685
uniprot id: A0A0P0CCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

512763:DC20 RS05545
gene id: 512763:DC20_RS05545
uniprot id: A0A0P0CQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

512763:DC20 RS00130
gene id: 512763:DC20_RS00130
uniprot id: A0A0P0BZV9
names: Similarity
messages: Belongs to the SUI1 family.

512763:DC20 RS16575
gene id: 512763:DC20_RS16575
uniprot id: A0A0P0CEM3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

512763:DC20 RS11650
gene id: 512763:DC20_RS11650
uniprot id: A0A0N7HWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

512763:DC20 RS07475
gene id: 512763:DC20_RS07475
uniprot id: A0A0P0C2G5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

512763:DC20 RS18065
gene id: 512763:DC20_RS18065
uniprot id: A0A0P0D150
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

512763:DC20 RS20690
gene id: 512763:DC20_RS20690
uniprot id: A0A0P0CZP0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

512763:DC20 RS18215
gene id: 512763:DC20_RS18215
uniprot id: A0A0P0C5S7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

512763:DC20 RS12215
gene id: 512763:DC20_RS12215
uniprot id: A0A0P0CSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

512763:DC20 RS01835
gene id: 512763:DC20_RS01835
uniprot id: A0A0P0CWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS03885
gene id: 512763:DC20_RS03885
uniprot id: A0A0P0C4Z8
names: Similarity
messages: Belongs to the thioredoxin family.

512763:DC20 RS13015
gene id: 512763:DC20_RS13015
uniprot id: A0A0P0CT49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

512763:DC20 RS16405
gene id: 512763:DC20_RS16405
uniprot id: A0A0N7HWV0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

512763:DC20 RS06000
gene id: 512763:DC20_RS06000
uniprot id: A0A0P0D0H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS08465
gene id: 512763:DC20_RS08465
uniprot id: A0A0P0C6N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

512763:DC20 RS00505
gene id: 512763:DC20_RS00505
uniprot id: A0A0N7HVY5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

512763:DC20 RS10435
gene id: 512763:DC20_RS10435
uniprot id: A0A0P0C7F1
names: Similarity
messages: Belongs to the peptidase S41A family.

512763:DC20 RS18740
gene id: 512763:DC20_RS18740
uniprot id: A0A0P0D1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

512763:DC20 RS09335
gene id: 512763:DC20_RS09335
uniprot id: A0A0P0CRQ0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

512763:DC20 RS11085
gene id: 512763:DC20_RS11085
uniprot id: A0A0N7HWJ3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07050
gene id: 512763:DC20_RS07050
uniprot id: A0A0P0CNM6
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS21035
gene id: 512763:DC20_RS21035
uniprot id: A0A0P0C6W5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

512763:DC20 RS09015
gene id: 512763:DC20_RS09015
uniprot id: A0A0P0CI95
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

512763:DC20 RS03000
gene id: 512763:DC20_RS03000
uniprot id: A0A0P0CPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

512763:DC20 RS09515
gene id: 512763:DC20_RS09515
uniprot id: A0A0P0CPG1
names: Similarity
messages: Belongs to the threonine aldolase family.

512763:DC20 RS11470
gene id: 512763:DC20_RS11470
uniprot id: A0A0N7HWK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

512763:DC20 RS02460
gene id: 512763:DC20_RS02460
uniprot id: A0A0P0CG83
names: Similarity
messages: Belongs to the EPSP synthase family.

512763:DC20 RS09560
gene id: 512763:DC20_RS09560
uniprot id: A0A0P0CXQ1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

512763:DC20 RS15415
gene id: 512763:DC20_RS15415
uniprot id: A0A0P0CXI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

512763:DC20 RS00305
gene id: 512763:DC20_RS00305
uniprot id: A0A0P0CFG4
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

512763:DC20 RS16830
gene id: 512763:DC20_RS16830
uniprot id: A0A0P0C5U8
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

512763:DC20 RS09400
gene id: 512763:DC20_RS09400
uniprot id: A0A0P0CX06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

512763:DC20 RS06050
gene id: 512763:DC20_RS06050
uniprot id: A0A0P0CNB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

512763:DC20 RS04665
gene id: 512763:DC20_RS04665
uniprot id: A0A0N7HW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

512763:DC20 RS12785
gene id: 512763:DC20_RS12785
uniprot id: A0A0P0CT06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

512763:DC20 RS21060
gene id: 512763:DC20_RS21060
uniprot id: A0A0P0CZU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

512763:DC20 RS07675
gene id: 512763:DC20_RS07675
uniprot id: A0A0P0CUB7
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS09740
gene id: 512763:DC20_RS09740
uniprot id: A0A0P0CV64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

512763:DC20 RS19920
gene id: 512763:DC20_RS19920
uniprot id: A0A0P0CB18
names: Similarity
messages: Belongs to the MQO family.

512763:DC20 RS01760
gene id: 512763:DC20_RS01760
uniprot id: A0A0N7HW08
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS18855
gene id: 512763:DC20_RS18855
uniprot id: A0A0P0CYW1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

512763:DC20 RS07150
gene id: 512763:DC20_RS07150
uniprot id: A0A0P0C1L3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

512763:DC20 RS07400
gene id: 512763:DC20_RS07400
uniprot id: A0A0P0CW88
names: Similarity
messages: Belongs to the peptidase C40 family.

512763:DC20 RS13595
gene id: 512763:DC20_RS13595
uniprot id: A0A0P0C4N3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

512763:DC20 RS06190
gene id: 512763:DC20_RS06190
uniprot id: A0A0P0CAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

512763:DC20 RS17360
gene id: 512763:DC20_RS17360
uniprot id: A0A0P0CXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

512763:DC20 RS13450
gene id: 512763:DC20_RS13450
uniprot id: A0A0P0CDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

512763:DC20 RS00455
gene id: 512763:DC20_RS00455
uniprot id: A0A0P0CFI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

512763:DC20 RS16565
gene id: 512763:DC20_RS16565
uniprot id: A0A0N7HWV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS12140
gene id: 512763:DC20_RS12140
uniprot id: A0A0P0CY22
names: Similarity
messages: Belongs to the pirin family.

512763:DC20 RS00875
gene id: 512763:DC20_RS00875
uniprot id: A0A0P0CRP5
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11755
gene id: 512763:DC20_RS11755
uniprot id: A0A0P0C7W2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

512763:DC20 RS16810
gene id: 512763:DC20_RS16810
uniprot id: A0A0P0CY35
names: Similarity
messages: Belongs to the ribF family.

512763:DC20 RS12535
gene id: 512763:DC20_RS12535
uniprot id: A0A0P0CJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS07460
gene id: 512763:DC20_RS07460
uniprot id: A0A0P0CU82
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

512763:DC20 RS12830
gene id: 512763:DC20_RS12830
uniprot id: A0A0N7HWM9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

512763:DC20 RS04450
gene id: 512763:DC20_RS04450
uniprot id: A0A0P0C0L0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS02165
gene id: 512763:DC20_RS02165
uniprot id: A0A0P0CUG5
names: Similarity
messages: Belongs to the peptidase S8 family.

512763:DC20 RS17035
gene id: 512763:DC20_RS17035
uniprot id: A0A0P0D014
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS09700
gene id: 512763:DC20_RS09700
uniprot id: A0A0P0C385
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

512763:DC20 RS14720
gene id: 512763:DC20_RS14720
uniprot id: A0A0N7HWR7
names: Similarity
messages: Belongs to the ArsC family.

512763:DC20 RS00125
gene id: 512763:DC20_RS00125
uniprot id: A0A0P0CTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

512763:DC20 RS01765
gene id: 512763:DC20_RS01765
uniprot id: A0A0P0CUB8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

512763:DC20 RS17095
gene id: 512763:DC20_RS17095
uniprot id: A0A0P0CY77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

512763:DC20 RS06285
gene id: 512763:DC20_RS06285
uniprot id: A0A0P0CTT9
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

512763:DC20 RS18260
gene id: 512763:DC20_RS18260
uniprot id: A0A0P0CV58
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

512763:DC20 RS12690
gene id: 512763:DC20_RS12690
uniprot id: A0A0N7HWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS15400
gene id: 512763:DC20_RS15400
uniprot id: A0A0P0CRQ3
names: Similarity
messages: Belongs to the universal stress protein A family.

512763:DC20 RS09615
gene id: 512763:DC20_RS09615
uniprot id: A0A0N7HWG5
names: Similarity
messages: Belongs to the UPF0102 family.

512763:DC20 RS11235
gene id: 512763:DC20_RS11235
uniprot id: A0A0P0C7N8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

512763:DC20 RS05360
gene id: 512763:DC20_RS05360
uniprot id: A0A0P0CTG4
names: Similarity
messages: Belongs to the UPF0234 family.

512763:DC20 RS02500
gene id: 512763:DC20_RS02500
uniprot id: A0A0P0C4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

512763:DC20 RS13455
gene id: 512763:DC20_RS13455
uniprot id: A0A0P0CQW0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

512763:DC20 RS15555
gene id: 512763:DC20_RS15555
uniprot id: A0A0P0CKQ7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

512763:DC20 RS18870
gene id: 512763:DC20_RS18870
uniprot id: A0A0P0D0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

512763:DC20 RS21055
gene id: 512763:DC20_RS21055
uniprot id: A0A0P0CBI1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

512763:DC20 RS13840
gene id: 512763:DC20_RS13840
uniprot id: A0A0P0CK18
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS05265
gene id: 512763:DC20_RS05265
uniprot id: A0A0P0CH61
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

512763:DC20 RS03450
gene id: 512763:DC20_RS03450
uniprot id: A0A0N7HW43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

512763:DC20 RS07630
gene id: 512763:DC20_RS07630
uniprot id: A0A0P0CUP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

512763:DC20 RS03110
gene id: 512763:DC20_RS03110
uniprot id: A0A0P0C9M5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

512763:DC20 RS17045
gene id: 512763:DC20_RS17045
uniprot id: A0A0P0C5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

512763:DC20 RS11300
gene id: 512763:DC20_RS11300
uniprot id: A0A0P0C7P9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

512763:DC20 RS08280
gene id: 512763:DC20_RS08280
uniprot id: A0A0P0CX49
names: Similarity
messages: Belongs to the RecJ family.

512763:DC20 RS11695
gene id: 512763:DC20_RS11695
uniprot id: A0A0P0CQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

512763:DC20 RS20255
gene id: 512763:DC20_RS20255
uniprot id: A0A0P0D1X6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

512763:DC20 RS03305
gene id: 512763:DC20_RS03305
uniprot id: A0A0N7HW40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

512763:DC20 RS07810
gene id: 512763:DC20_RS07810
uniprot id: A0A0P0CUD8
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS03680
gene id: 512763:DC20_RS03680
uniprot id: A0A0P0C4X9
names: Similarity
messages: Belongs to the CinA family.

512763:DC20 RS16710
gene id: 512763:DC20_RS16710
uniprot id: A0A0P0C542
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

512763:DC20 RS12520
gene id: 512763:DC20_RS12520
uniprot id: A0A0P0CYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS02295
gene id: 512763:DC20_RS02295
uniprot id: A0A0P0CUI5
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS09120
gene id: 512763:DC20_RS09120
uniprot id: A0A0N7HWF5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

512763:DC20 RS15855
gene id: 512763:DC20_RS15855
uniprot id: A0A0N7HWT8
names: Function
names: Similarity
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

512763:DC20 RS01320
gene id: 512763:DC20_RS01320
uniprot id: A0A0P0CU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

512763:DC20 RS13865
gene id: 512763:DC20_RS13865
uniprot id: A0A0P0CWU8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

512763:DC20 RS02600
gene id: 512763:DC20_RS02600
uniprot id: A0A0P0C0P3
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

512763:DC20 RS15250
gene id: 512763:DC20_RS15250
uniprot id: A0A0P0C4K5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

512763:DC20 RS20655
gene id: 512763:DC20_RS20655
uniprot id: A0A0N7HX37
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

512763:DC20 RS05100
gene id: 512763:DC20_RS05100
uniprot id: A0A0P0C0X0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS15800
gene id: 512763:DC20_RS15800
uniprot id: A0A0P0CKT1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

512763:DC20 RS04400
gene id: 512763:DC20_RS04400
uniprot id: A0A0N7HX66
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

512763:DC20 RS06385
gene id: 512763:DC20_RS06385
uniprot id: A0A0P0C1Y9
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

512763:DC20 RS17875
gene id: 512763:DC20_RS17875
uniprot id: A0A0P0CLI0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS19595
gene id: 512763:DC20_RS19595
uniprot id: A0A0P0CVP4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

512763:DC20 RS13880
gene id: 512763:DC20_RS13880
uniprot id: A0A0P0C4R9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

512763:DC20 RS06735
gene id: 512763:DC20_RS06735
uniprot id: A0A0P0CW11
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS02430
gene id: 512763:DC20_RS02430
uniprot id: A0A0P0CS92
names: Similarity
messages: Belongs to the ClpA/ClpB family.

512763:DC20 RS03165
gene id: 512763:DC20_RS03165
uniprot id: A0A0N7HW37
names: Similarity
messages: Belongs to the aspartokinase family.

512763:DC20 RS06670
gene id: 512763:DC20_RS06670
uniprot id: A0A0P0C1G5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

512763:DC20 RS13825
gene id: 512763:DC20_RS13825
uniprot id: A0A0P0C420
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

512763:DC20 RS13180
gene id: 512763:DC20_RS13180
uniprot id: A0A0P0CJU8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

512763:DC20 RS03495
gene id: 512763:DC20_RS03495
uniprot id: A0A0P0CNA9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

512763:DC20 RS03075
gene id: 512763:DC20_RS03075
uniprot id: A0A0P0C0V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS01675
gene id: 512763:DC20_RS01675
uniprot id: A0A0P0CUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

512763:DC20 RS06960
gene id: 512763:DC20_RS06960
uniprot id: A0A0P0C286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

512763:DC20 RS11405
gene id: 512763:DC20_RS11405
uniprot id: A0A0P0C351
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS20525
gene id: 512763:DC20_RS20525
uniprot id: A0A0P0D209
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

512763:DC20 RS20200
gene id: 512763:DC20_RS20200
uniprot id: A0A0P0CMF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

512763:DC20 RS17145
gene id: 512763:DC20_RS17145
uniprot id: A0A0P0C9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

512763:DC20 RS10715
gene id: 512763:DC20_RS10715
uniprot id: A0A0N7HWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

512763:DC20 RS01825
gene id: 512763:DC20_RS01825
uniprot id: A0A0P0CNY6
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01635
gene id: 512763:DC20_RS01635
uniprot id: A0A0P0C943
names: Similarity
messages: Belongs to the glutathione peroxidase family.

512763:DC20 RS03530
gene id: 512763:DC20_RS03530
uniprot id: A0A0P0CST4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

512763:DC20 RS12740
gene id: 512763:DC20_RS12740
uniprot id: A0A0N7HWM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

512763:DC20 RS18195
gene id: 512763:DC20_RS18195
uniprot id: A0A0P0D0I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS09630
gene id: 512763:DC20_RS09630
uniprot id: A0A0P0C379
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS01315
gene id: 512763:DC20_RS01315
uniprot id: A0A0P0C075
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS13900
gene id: 512763:DC20_RS13900
uniprot id: A0A0P0D2X3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

512763:DC20 RS09695
gene id: 512763:DC20_RS09695
uniprot id: A0A0P0CX44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

512763:DC20 RS09200
gene id: 512763:DC20_RS09200
uniprot id: A0A0P0CWX6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

512763:DC20 RS18385
gene id: 512763:DC20_RS18385
uniprot id: A0A0P0CAB3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

512763:DC20 RS03060
gene id: 512763:DC20_RS03060
uniprot id: A0A0N7HW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

512763:DC20 RS07060
gene id: 512763:DC20_RS07060
uniprot id: A0A0P0CU29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS12500
gene id: 512763:DC20_RS12500
uniprot id: A0A0P0CSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

512763:DC20 RS01220
gene id: 512763:DC20_RS01220
uniprot id: A0A0P0C413
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

512763:DC20 RS08520
gene id: 512763:DC20_RS08520
uniprot id: A0A0N7HWE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

512763:DC20 RS14970
gene id: 512763:DC20_RS14970
uniprot id: A0A0N7HWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

512763:DC20 RS06160
gene id: 512763:DC20_RS06160
uniprot id: A0A0P0CQD9
names: Similarity
messages: Belongs to the AHA1 family.

512763:DC20 RS02280
gene id: 512763:DC20_RS02280
uniprot id: A0A0P0CP50
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS19700
gene id: 512763:DC20_RS19700
uniprot id: A0A0N7HX17
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

512763:DC20 RS00665
gene id: 512763:DC20_RS00665
uniprot id: A0A0P0CFL0
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS15105
gene id: 512763:DC20_RS15105
uniprot id: A0A0P0C4I5
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

512763:DC20 RS17135
gene id: 512763:DC20_RS17135
uniprot id: A0A0P0CEW4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS03185
gene id: 512763:DC20_RS03185
uniprot id: A0A0P0CMJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

512763:DC20 RS13710
gene id: 512763:DC20_RS13710
uniprot id: A0A0P0C8K7
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS04220
gene id: 512763:DC20_RS04220
uniprot id: A0A0P0C533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

512763:DC20 RS02320
gene id: 512763:DC20_RS02320
uniprot id: A0A0P0CG64
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

512763:DC20 RS10735
gene id: 512763:DC20_RS10735
uniprot id: A0A0P0CCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

512763:DC20 RS14540
gene id: 512763:DC20_RS14540
uniprot id: A0A0N7HWR3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

512763:DC20 RS08190
gene id: 512763:DC20_RS08190
uniprot id: A0A0P0C2P8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

512763:DC20 RS04340
gene id: 512763:DC20_RS04340
uniprot id: A0A0P0CVF8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

512763:DC20 RS17710
gene id: 512763:DC20_RS17710
uniprot id: A0A0N7HXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

512763:DC20 RS14005
gene id: 512763:DC20_RS14005
uniprot id: A0A0P0CR24
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

512763:DC20 RS20775
gene id: 512763:DC20_RS20775
uniprot id: A0A0P0CBE2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

512763:DC20 RS21475
gene id: 512763:DC20_RS21475
uniprot id: A0A0P0CD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS13320
gene id: 512763:DC20_RS13320
uniprot id: A0A0P0CDC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

512763:DC20 RS16900
gene id: 512763:DC20_RS16900
uniprot id: A0A0P0C5V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

512763:DC20 RS11645
gene id: 512763:DC20_RS11645
uniprot id: A0A0P0CVZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

512763:DC20 RS09245
gene id: 512763:DC20_RS09245
uniprot id: A0A0P0CPD4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

512763:DC20 RS03135
gene id: 512763:DC20_RS03135
uniprot id: A0A0P0C4T2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

512763:DC20 RS01730
gene id: 512763:DC20_RS01730
uniprot id: A0A0P0C488
names: Similarity
messages: Belongs to the Fur family.

512763:DC20 RS10045
gene id: 512763:DC20_RS10045
uniprot id: A0A0P0CX92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

512763:DC20 RS18305
gene id: 512763:DC20_RS18305
uniprot id: A0A0P0CSU5
names: Subunit
messages: Homodimer.

512763:DC20 RS03720
gene id: 512763:DC20_RS03720
uniprot id: A0A0P0CGQ7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

512763:DC20 RS11510
gene id: 512763:DC20_RS11510
uniprot id: A0A0N7HWK2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS00975
gene id: 512763:DC20_RS00975
uniprot id: A0A0P0CRQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

512763:DC20 RS18940
gene id: 512763:DC20_RS18940
uniprot id: A0A0N7HX01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

512763:DC20 RS09470
gene id: 512763:DC20_RS09470
uniprot id: A0A0P0CRR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

512763:DC20 RS11935
gene id: 512763:DC20_RS11935
uniprot id: A0A0P0C419
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

512763:DC20 RS05250
gene id: 512763:DC20_RS05250
uniprot id: A0A0P0C1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS04165
gene id: 512763:DC20_RS04165
uniprot id: A0A0P0CV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS21095
gene id: 512763:DC20_RS21095
uniprot id: A0A0P0CMY0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

512763:DC20 RS20500
gene id: 512763:DC20_RS20500
uniprot id: A0A0P0CZK9
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS09495
gene id: 512763:DC20_RS09495
uniprot id: A0A0P0C2E2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

512763:DC20 RS05255
gene id: 512763:DC20_RS05255
uniprot id: A0A0P0CVW2
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

512763:DC20 RS03085
gene id: 512763:DC20_RS03085
uniprot id: A0A0P0CUW5
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

512763:DC20 RS04710
gene id: 512763:DC20_RS04710
uniprot id: A0A0P0CVE1
names: Similarity
messages: Belongs to the MreC family.

512763:DC20 RS16355
gene id: 512763:DC20_RS16355
uniprot id: A0A0P0CS25
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

512763:DC20 RS08885
gene id: 512763:DC20_RS08885
uniprot id: A0A0P0CUV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

512763:DC20 RS01420
gene id: 512763:DC20_RS01420
uniprot id: A0A0P0C432
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

512763:DC20 RS16555
gene id: 512763:DC20_RS16555
uniprot id: A0A0P0C529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

512763:DC20 RS07335
gene id: 512763:DC20_RS07335
uniprot id: A0A0P0CQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

512763:DC20 RS04495
gene id: 512763:DC20_RS04495
uniprot id: A0A0P0CPU9
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

512763:DC20 RS05120
gene id: 512763:DC20_RS05120
uniprot id: A0A0P0CN49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

512763:DC20 RS01665
gene id: 512763:DC20_RS01665
uniprot id: A0A0P0CUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

512763:DC20 RS10545
gene id: 512763:DC20_RS10545
uniprot id: A0A0P0C7G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

512763:DC20 RS06270
gene id: 512763:DC20_RS06270
uniprot id: A0A0P0CAR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

512763:DC20 RS21845
gene id: 512763:DC20_RS21845
uniprot id: A0A0N7HXC9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

512763:DC20 RS00540
gene id: 512763:DC20_RS00540
uniprot id: A0A0P0CFJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

512763:DC20 RS13185
gene id: 512763:DC20_RS13185
uniprot id: A0A0P0CDB0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

512763:DC20 RS06005
gene id: 512763:DC20_RS06005
uniprot id: A0A0P0C1U6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

512763:DC20 RS03180
gene id: 512763:DC20_RS03180
uniprot id: A0A0P0C9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

512763:DC20 RS01785
gene id: 512763:DC20_RS01785
uniprot id: A0A0P0BZM0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS11675
gene id: 512763:DC20_RS11675
uniprot id: A0A0P0C386
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

512763:DC20 RS05995
gene id: 512763:DC20_RS05995
uniprot id: A0A0P0CVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS21070
gene id: 512763:DC20_RS21070
uniprot id: A0A0P0CWA1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

512763:DC20 RS05725
gene id: 512763:DC20_RS05725
uniprot id: A0A0P0CW28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

512763:DC20 RS17115
gene id: 512763:DC20_RS17115
uniprot id: A0A0N7HWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

512763:DC20 RS10725
gene id: 512763:DC20_RS10725
uniprot id: A0A0P0CIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

512763:DC20 RS22165
gene id: 512763:DC20_RS22165
uniprot id: A0A0P0D1U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

512763:DC20 RS08045
gene id: 512763:DC20_RS08045
uniprot id: A0A0N7HWD4
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS15360
gene id: 512763:DC20_RS15360
uniprot id: A0A0P0CU07
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS03505
gene id: 512763:DC20_RS03505
uniprot id: A0A0P0C089
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

512763:DC20 RS02940
gene id: 512763:DC20_RS02940
uniprot id: A0A0P0CUS6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

512763:DC20 RS11945
gene id: 512763:DC20_RS11945
uniprot id: A0A0P0C3B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

512763:DC20 RS10900
gene id: 512763:DC20_RS10900
uniprot id: A0A0P0C3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

512763:DC20 RS11595
gene id: 512763:DC20_RS11595
uniprot id: A0A0P0CSN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

512763:DC20 RS07435
gene id: 512763:DC20_RS07435
uniprot id: A0A0P0CHR1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

512763:DC20 RS04675
gene id: 512763:DC20_RS04675
uniprot id: A0A0P0CH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

512763:DC20 RS17180
gene id: 512763:DC20_RS17180
uniprot id: A0A0P0D033
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

512763:DC20 RS02520
gene id: 512763:DC20_RS02520
uniprot id: A0A0P0CUL9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

512763:DC20 RS11265
gene id: 512763:DC20_RS11265
uniprot id: A0A0N7HWJ7
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

512763:DC20 RS04490
gene id: 512763:DC20_RS04490
uniprot id: A0A0P0CT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

512763:DC20 RS15270
gene id: 512763:DC20_RS15270
uniprot id: A0A0P0CRN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

512763:DC20 RS13330
gene id: 512763:DC20_RS13330
uniprot id: A0A0N7HWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

512763:DC20 RS08470
gene id: 512763:DC20_RS08470
uniprot id: A0A0N7HWE2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

512763:DC20 RS16855
gene id: 512763:DC20_RS16855
uniprot id: A0A0P0CL69
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

512763:DC20 RS09345
gene id: 512763:DC20_RS09345
uniprot id: A0A0P0C343
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

512763:DC20 RS21975
gene id: 512763:DC20_RS21975
uniprot id: A0A0P0CI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

512763:DC20 RS15275
gene id: 512763:DC20_RS15275
uniprot id: A0A0P0C954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

512763:DC20 RS02640
gene id: 512763:DC20_RS02640
uniprot id: A0A0P0C4L3
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS10655
gene id: 512763:DC20_RS10655
uniprot id: A0A0P0CY27
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

512763:DC20 RS04330
gene id: 512763:DC20_RS04330
uniprot id: A0A0N7HW61
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07565
gene id: 512763:DC20_RS07565
uniprot id: A0A0P0CWV4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

512763:DC20 RS21015
gene id: 512763:DC20_RS21015
uniprot id: A0A0P0D1R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

512763:DC20 RS16985
gene id: 512763:DC20_RS16985
uniprot id: A0A0P0D0L4
names: Similarity
messages: Belongs to the ParB family.

512763:DC20 RS09250
gene id: 512763:DC20_RS09250
uniprot id: A0A0P0C6Y0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

512763:DC20 RS05755
gene id: 512763:DC20_RS05755
uniprot id: A0A0P0CAK6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

512763:DC20 RS18670
gene id: 512763:DC20_RS18670
uniprot id: A0A0P0CVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

512763:DC20 RS04625
gene id: 512763:DC20_RS04625
uniprot id: A0A0P0D0C9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

512763:DC20 RS03460
gene id: 512763:DC20_RS03460
uniprot id: A0A0P0CML7
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11660
gene id: 512763:DC20_RS11660
uniprot id: A0A0P0CXV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

512763:DC20 RS10975
gene id: 512763:DC20_RS10975
uniprot id: A0A0P0CNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

512763:DC20 RS07030
gene id: 512763:DC20_RS07030
uniprot id: A0A0P0C1K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS13075
gene id: 512763:DC20_RS13075
uniprot id: A0A0P0CWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

512763:DC20 RS19780
gene id: 512763:DC20_RS19780
uniprot id: A0A0P0CM89
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS11730
gene id: 512763:DC20_RS11730
uniprot id: A0A0N7HWK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

512763:DC20 RS06940
gene id: 512763:DC20_RS06940
uniprot id: A0A0P0CU13
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

512763:DC20 RS15335
gene id: 512763:DC20_RS15335
uniprot id: A0A0N7HWS9
names: Similarity
messages: Belongs to the SusD family.

512763:DC20 RS04280
gene id: 512763:DC20_RS04280
uniprot id: A0A0N7HW60
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

512763:DC20 RS23165
gene id: 512763:DC20_RS23165
uniprot id: A0A0P0CNV4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

512763:DC20 RS04860
gene id: 512763:DC20_RS04860
uniprot id: A0A0P0CH34
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

512763:DC20 RS00640
gene id: 512763:DC20_RS00640
uniprot id: A0A0P0CU02
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

512763:DC20 RS15110
gene id: 512763:DC20_RS15110
uniprot id: A0A0P0CKH7
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

512763:DC20 RS11920
gene id: 512763:DC20_RS11920
uniprot id: A0A0P0CSS1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

512763:DC20 RS07130
gene id: 512763:DC20_RS07130
uniprot id: A0A0P0CW53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

512763:DC20 RS12810
gene id: 512763:DC20_RS12810
uniprot id: A0A0P0C3L7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

512763:DC20 RS21320
gene id: 512763:DC20_RS21320
uniprot id: A0A0P0CBM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

512763:DC20 RS10040
gene id: 512763:DC20_RS10040
uniprot id: A0A0P0CS10
names: Similarity
messages: Belongs to the LOG family.

512763:DC20 RS07105
gene id: 512763:DC20_RS07105
uniprot id: A0A0P0CNM9
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS07575
gene id: 512763:DC20_RS07575
uniprot id: A0A0P0CHS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

512763:DC20 RS18930
gene id: 512763:DC20_RS18930
uniprot id: A0A0P0CVF4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

512763:DC20 RS11555
gene id: 512763:DC20_RS11555
uniprot id: A0A0P0CYC0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

512763:DC20 RS10535
gene id: 512763:DC20_RS10535
uniprot id: A0A0P0CPT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

512763:DC20 RS19600
gene id: 512763:DC20_RS19600
uniprot id: A0A0P0D172
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

512763:DC20 RS17715
gene id: 512763:DC20_RS17715
uniprot id: A0A0P0C660
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

512763:DC20 RS16660
gene id: 512763:DC20_RS16660
uniprot id: A0A0P0CVA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

512763:DC20 RS16530
gene id: 512763:DC20_RS16530
uniprot id: A0A0N7HXA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

512763:DC20 RS12695
gene id: 512763:DC20_RS12695
uniprot id: A0A0P0C8I6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

512763:DC20 RS20045
gene id: 512763:DC20_RS20045
uniprot id: A0A0P0CG10
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

512763:DC20 RS15665
gene id: 512763:DC20_RS15665
uniprot id: A0A0P0CU53
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS15320
gene id: 512763:DC20_RS15320
uniprot id: A0A0P0CE41
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

512763:DC20 RS01295
gene id: 512763:DC20_RS01295
uniprot id: A0A0P0C416
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

512763:DC20 RS08610
gene id: 512763:DC20_RS08610
uniprot id: A0A0N7HWE5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

512763:DC20 RS03920
gene id: 512763:DC20_RS03920
uniprot id: A0A0P0C0F4
names: Subcellular Location Annotation
messages: Membrane

512763:DC20 RS12030
gene id: 512763:DC20_RS12030
uniprot id: A0A0N7HWL3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

512763:DC20 RS21110
gene id: 512763:DC20_RS21110
uniprot id: A0A0P0CU23
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

512763:DC20 RS10595
gene id: 512763:DC20_RS10595
uniprot id: A0A0P0CY16
names: Similarity
messages: Belongs to the peptidase S66 family.

512763:DC20 RS17415
gene id: 512763:DC20_RS17415
uniprot id: A0A0P0D0U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.