510516:AO090701000065
gene id: 510516:AO090701000065
uniprot id: Q2U9E1
names: Similarity
messages: Belongs to the actin family.

510516:AO090012001013
gene id: 510516:AO090012001013
uniprot id: Q2UBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

510516:AO090003000518
gene id: 510516:AO090003000518
uniprot id: Q2UL78
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000666
gene id: 510516:AO090001000666
uniprot id: Q2UMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

510516:AO090120000306
gene id: 510516:AO090120000306
uniprot id: Q2U6B5
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

510516:AO090012000612
gene id: 510516:AO090012000612
uniprot id: Q2UCF5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000592
gene id: 510516:AO090010000592
uniprot id: Q2TWE6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

510516:AO090005001301
gene id: 510516:AO090005001301
uniprot id: Q2UQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090001000593
gene id: 510516:AO090001000593
uniprot id: Q2UMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with atg5.
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).

510516:AO090003001520
gene id: 510516:AO090003001520
uniprot id: Q2UIQ7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000468
gene id: 510516:AO090003000468
uniprot id: Q2ULC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

510516:AO090010000040
gene id: 510516:AO090010000040
uniprot id: Q2TXR4
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

510516:AO090701000359
gene id: 510516:AO090701000359
uniprot id: Q2U8N4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

510516:AO090120000397
gene id: 510516:AO090120000397
uniprot id: Q2U636
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
messages: Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.
messages: Nucleus
messages: cytosol

510516:AO090005000449
gene id: 510516:AO090005000449
uniprot id: Q2USF2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090005000111
gene id: 510516:AO090005000111
uniprot id: Q2UT90
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

510516:AO090102000365
gene id: 510516:AO090102000365
uniprot id: Q2UAJ1
names: Similarity
messages: Belongs to the VPS54 family.

510516:AO090102000512
gene id: 510516:AO090102000512
uniprot id: Q2UA75
names: Similarity
messages: Belongs to the WD repeat PWP2 family.

510516:AO090023000001
gene id: 510516:AO090023000001
uniprot id: Q2UIM2
names: Domain
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Able to hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan.
messages: Belongs to the glycosyl hydrolase 54 family.
messages: Organized into two domains: an N-terminal catalytic domain and a C-terminal arabinose-binding domain (ABD).
messages: Repressed by glucose.
messages: Secreted

510516:AO090023000508
gene id: 510516:AO090023000508
uniprot id: Q2UHB9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

510516:AO090011000831
gene id: 510516:AO090011000831
uniprot id: Q2TZJ3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000412
gene id: 510516:AO090120000412
uniprot id: Q2U622
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

510516:AO090103000081
gene id: 510516:AO090103000081
uniprot id: Q2TYW7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090166000084
gene id: 510516:AO090166000084
uniprot id: Q2U9N2
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

510516:AO090001000558
gene id: 510516:AO090001000558
uniprot id: Q2UMZ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

510516:AO090120000043
gene id: 510516:AO090120000043
uniprot id: Q2U6Y5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

510516:AO090701000841
gene id: 510516:AO090701000841
uniprot id: Q2U7H1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

510516:AO090011000745
gene id: 510516:AO090011000745
uniprot id: Q75P26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone. Displays the greatest hydrolytic activity toward alpha-naphthylacetate (C2), lower activity toward alpha-naphthylpropionate (C3) and no detectable activity toward acyl-chain substrates containing four or more carbon atoms.
messages: Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
messages: Monomer.
messages: Secreted
messages: The C-terminal carbohydrate-binding module (CBM) extension found in soem acetylxylan esterases from other species is absent.

510516:AO090038000573
gene id: 510516:AO090038000573
uniprot id: Q2U275
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

510516:AO090003000402
gene id: 510516:AO090003000402
uniprot id: Q2ULI1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

510516:AO090120000093
gene id: 510516:AO090120000093
uniprot id: Q2U6U4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000888
gene id: 510516:AO090005000888
uniprot id: Q2URC0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090103000013
gene id: 510516:AO090103000013
uniprot id: Q2TZ22
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000399
gene id: 510516:AO090012000399
uniprot id: Q2UCY3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090038000287
gene id: 510516:AO090038000287
uniprot id: Q2U2W9
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

510516:AO090012000036
gene id: 510516:AO090012000036
uniprot id: Q2UDT5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090003001047
gene id: 510516:AO090003001047
uniprot id: Q2UJW4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

510516:AO090020000093
gene id: 510516:AO090020000093
uniprot id: Q2U534
names: Subunit
messages: Homodimer.

510516:AO090038000218
gene id: 510516:AO090038000218
uniprot id: Q2U329
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

510516:AO090003000030
gene id: 510516:AO090003000030
uniprot id: Q2UME6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

510516:AO090012000001
gene id: 510516:AO090012000001
uniprot id: Q2UDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090026000490
gene id: 510516:AO090026000490
uniprot id: Q2UET5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

510516:AO090102000220
gene id: 510516:AO090102000220
uniprot id: Q2UAV4
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

510516:AO090020000406
gene id: 510516:AO090020000406
uniprot id: Q2U4B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

510516:AO090701000799
gene id: 510516:AO090701000799
uniprot id: Q2U7K8
names: Subcellular Location Annotation
messages: Peroxisome membrane

510516:AO090124000021
gene id: 510516:AO090124000021
uniprot id: Q2U792
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000577
gene id: 510516:AO090026000577
uniprot id: Q2UEK9
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Does not affect the production of astellolides.
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: MFS-type transporter; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). Seems not to be involved in astellolides translocation (PubMed:27628599).
messages: Membrane

510516:AO090003001402
gene id: 510516:AO090003001402
uniprot id: Q2UJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

510516:AO090009000596
gene id: 510516:AO090009000596
uniprot id: Q2UTT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

510516:AO090023000725
gene id: 510516:AO090023000725
uniprot id: Q2UGS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

510516:AO090102000207
gene id: 510516:AO090102000207
uniprot id: Q2UAW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090003000290
gene id: 510516:AO090003000290
uniprot id: Q2ULS2
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

510516:AO090011000636
gene id: 510516:AO090011000636
uniprot id: Q2U010
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

510516:AO090701000884
gene id: 510516:AO090701000884
uniprot id: Q2U7D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the faeC family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
messages: Secreted

510516:AO090009000384
gene id: 510516:AO090009000384
uniprot id: Q2UUB2
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

510516:AO090120000434
gene id: 510516:AO090120000434
uniprot id: Q2U603
names: Similarity
messages: Belongs to the MNN1/MNT family.

510516:AO090003000805
gene id: 510516:AO090003000805
uniprot id: Q2UKH6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

510516:AO090012000307
gene id: 510516:AO090012000307
uniprot id: Q2UD59
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090701000730
gene id: 510516:AO090701000730
uniprot id: Q2U7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

510516:AO090005000884
gene id: 510516:AO090005000884
uniprot id: Q2URC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

510516:AO090026000627
gene id: 510516:AO090026000627
uniprot id: Q2UEG5
names: Similarity
messages: Belongs to the yippee family.

510516:AO090026000616
gene id: 510516:AO090026000616
uniprot id: Q2UEH6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

510516:AO090005001230
gene id: 510516:AO090005001230
uniprot id: Q2UQI7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

510516:AO090001000024
gene id: 510516:AO090001000024
uniprot id: Q2UPC7
names: Cofactor
names: Disruption Phenotype
names: Function
names: Similarity
messages: Abolishes completely the formation of aspirochlorine and leads to the accumulation of dechloroaspirochlorine (PubMed:25302411).
messages: Belongs to the flavin-dependent halogenase family.
messages: Binds 1 FAD per subunit.
messages: Flavin-dependent halogenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090009000128
gene id: 510516:AO090009000128
uniprot id: Q2UUY1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000843
gene id: 510516:AO090011000843
uniprot id: Q2TZI2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

510516:AO090009000607
gene id: 510516:AO090009000607
uniprot id: Q2UTS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

510516:AO090102000121
gene id: 510516:AO090102000121
uniprot id: Q2UB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

510516:AO090023000072
gene id: 510516:AO090023000072
uniprot id: Q2UIF7
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090120000359
gene id: 510516:AO090120000359
uniprot id: Q2U668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

510516:AO090001000733
gene id: 510516:AO090001000733
uniprot id: Q00248
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

510516:AO090206000073
gene id: 510516:AO090206000073
uniprot id: Q2PIT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28E subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
messages: Monomer.
messages: Secreted

510516:AO090701000057
gene id: 510516:AO090701000057
uniprot id: Q2U9E8
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

510516:AO090001000384
gene id: 510516:AO090001000384
uniprot id: Q2UNF8
names: Similarity
messages: Belongs to the paxB family.

510516:AO090023000503
gene id: 510516:AO090023000503
uniprot id: Q2UHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

510516:AO090005000838
gene id: 510516:AO090005000838
uniprot id: Q2URG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Membrane

510516:AO090005000284
gene id: 510516:AO090005000284
uniprot id: Q2USV0
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

510516:AO090003000095
gene id: 510516:AO090003000095
uniprot id: Q2UM89
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

510516:AO090020000659
gene id: 510516:AO090020000659
uniprot id: Q2U3Q8
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

510516:AO090120000486
gene id: 510516:AO090120000486
uniprot id: Q2U5W2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

510516:AO090003000864
gene id: 510516:AO090003000864
uniprot id: Q2UKC6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000476
gene id: 510516:AO090010000476
uniprot id: Q2TWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity).

510516:AO090003001010
gene id: 510516:AO090003001010
uniprot id: Q2UJZ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

510516:AO090020000615
gene id: 510516:AO090020000615
uniprot id: Q2U3U4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

510516:AO090005000412
gene id: 510516:AO090005000412
uniprot id: Q2USI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

510516:AO090003001209
gene id: 510516:AO090003001209
uniprot id: Q12558
names: Function
names: Induction
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: By maltose.
messages: Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.

510516:AO090102000400
gene id: 510516:AO090102000400
uniprot id: Q2UAG4
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

510516:AO090005001017
gene id: 510516:AO090005001017
uniprot id: Q2UR13
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

510516:AO090102000413
gene id: 510516:AO090102000413
uniprot id: Q2UAF3
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090102000344
gene id: 510516:AO090102000344
uniprot id: Q2UAL0
names: Similarity
messages: Belongs to the chloroperoxidase family.

510516:AO090010000222
gene id: 510516:AO090010000222
uniprot id: Q2TXA4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000443
gene id: 510516:AO090012000443
uniprot id: Q2UCU5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090023000521
gene id: 510516:AO090023000521
uniprot id: Q2UHA6
names: Similarity
messages: Belongs to the DDB1 family.

510516:AO090005001538
gene id: 510516:AO090005001538
uniprot id: Q2UPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

510516:AO090012000727
gene id: 510516:AO090012000727
uniprot id: Q2UC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

510516:AO090120000339
gene id: 510516:AO090120000339
uniprot id: Q2U686
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

510516:AO090701000633
gene id: 510516:AO090701000633
uniprot id: Q2U7Z5
names: Similarity
messages: Belongs to the CoA-transferase III family.

510516:AO090011000757
gene id: 510516:AO090011000757
uniprot id: Q2TZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides (By similarity).
messages: Secreted

510516:AO090003000005
gene id: 510516:AO090003000005
uniprot id: Q2UMH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

510516:AO090026000294
gene id: 510516:AO090026000294
uniprot id: Q2UF96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

510516:AO090005000825
gene id: 510516:AO090005000825
uniprot id: Q2URH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

510516:AO090012000802
gene id: 510516:AO090012000802
uniprot id: Q2UBZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

510516:AO090701000427
gene id: 510516:AO090701000427
uniprot id: Q2U8H7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

510516:AO090009000513
gene id: 510516:AO090009000513
uniprot id: Q2UU07
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

510516:AO090023000962
gene id: 510516:AO090023000962
uniprot id: Q2UG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

510516:AO090023000190
gene id: 510516:AO090023000190
uniprot id: Q2UI52
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090701000813
gene id: 510516:AO090701000813
uniprot id: Q2U7J6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090038000485
gene id: 510516:AO090038000485
uniprot id: Q2U2E6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000439
gene id: 510516:AO090010000439
uniprot id: Q2TWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

510516:AO090124000075
gene id: 510516:AO090124000075
uniprot id: Q2U742
names: Similarity
messages: Belongs to the bystin family.

510516:AO090124000051
gene id: 510516:AO090124000051
uniprot id: Q2U765
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

510516:AO090038000435
gene id: 510516:AO090038000435
uniprot id: Q2U2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090005000026
gene id: 510516:AO090005000026
uniprot id: Q2UTG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090120000381
gene id: 510516:AO090120000381
uniprot id: Q2U649
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

510516:AO090009000008
gene id: 510516:AO090009000008
uniprot id: Q2UV81
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000533
gene id: 510516:AO090012000533
uniprot id: Q2UCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

510516:AO090102000295
gene id: 510516:AO090102000295
uniprot id: Q2UAP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
messages: Mitochondrion inner membrane

510516:AO090005000078
gene id: 510516:AO090005000078
uniprot id: Q2UTC1
names: Cofactor
messages: Binds 2 manganese ions per subunit.

510516:AO090011000340
gene id: 510516:AO090011000340
uniprot id: Q2U0Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090001000667
gene id: 510516:AO090001000667
uniprot id: Q2UMQ2
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

510516:AO090012000626
gene id: 510516:AO090012000626
uniprot id: Q2UCE3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

510516:AO090701000833
gene id: 510516:AO090701000833
uniprot id: Q2U7H8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090138000047
gene id: 510516:AO090138000047
uniprot id: Q2U1Y5
names: Similarity
messages: Belongs to the RutC family.

510516:AO090011000349
gene id: 510516:AO090011000349
uniprot id: Q2U0Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
messages: Secreted

510516:AO090011000027
gene id: 510516:AO090011000027
uniprot id: Q2U1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 75 family.
messages: Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall. Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity (By similarity).
messages: Secreted

510516:AO090038000592
gene id: 510516:AO090038000592
uniprot id: Q2U258
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

510516:AO090038000392
gene id: 510516:AO090038000392
uniprot id: Q2U2M8
names: Function
names: Subunit
messages: Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
messages: Interacts with lipid droplet proteins.

510516:AO090005001229
gene id: 510516:AO090005001229
uniprot id: Q2UQI8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003001442
gene id: 510516:AO090003001442
uniprot id: Q2UIX1
names: Similarity
messages: Belongs to the DapA family.

510516:AO090023000500
gene id: 510516:AO090023000500
uniprot id: Q2UHC5
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

510516:AO090001000582
gene id: 510516:AO090001000582
uniprot id: Q2UMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tannase family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
messages: Secreted

510516:AO090138000114
gene id: 510516:AO090138000114
uniprot id: Q2U1S6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090003000725
gene id: 510516:AO090003000725
uniprot id: Q9HGY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: Homodimer.

510516:AO090102000607
gene id: 510516:AO090102000607
uniprot id: Q2U9Z3
names: Function
names: Similarity
messages: Belongs to the LCL2 family.
messages: Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.

510516:AO090005001553
gene id: 510516:AO090005001553
uniprot id: Q2UPQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates (By similarity).
messages: Secreted

510516:AO090023000761
gene id: 510516:AO090023000761
uniprot id: Q2UGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC5 family.
messages: Cytoplasm
messages: May be involved in a process influencing telomere capping.

510516:AO090010000096
gene id: 510516:AO090010000096
uniprot id: Q2TXL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

510516:AO090023000342
gene id: 510516:AO090023000342
uniprot id: Q2UHR5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090020000410
gene id: 510516:AO090020000410
uniprot id: Q2U4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090023000856
gene id: 510516:AO090023000856
uniprot id: Q2UGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Mitochondrion matrix

510516:AO090023000460
gene id: 510516:AO090023000460
uniprot id: Q2UHG1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090001000670
gene id: 510516:AO090001000670
uniprot id: Q2UMP9
names: Similarity
messages: Belongs to the peptidase C12 family.

510516:AO090003000929
gene id: 510516:AO090003000929
uniprot id: Q2UK70
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

510516:AO090005000945
gene id: 510516:AO090005000945
uniprot id: Q2UR69
names: Subcellular Location Annotation
messages: Secreted

510516:AO090308000018
gene id: 510516:AO090308000018
uniprot id: Q2UPF3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090005000730
gene id: 510516:AO090005000730
uniprot id: Q2URQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

510516:AO090009000405
gene id: 510516:AO090009000405
uniprot id: Q2UU95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane
messages: Monomer.

510516:AO090001000030
gene id: 510516:AO090001000030
uniprot id: Q2UPC2
names: Function
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Gamma-glutamyl cyclotransferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090005000956
gene id: 510516:AO090005000956
uniprot id: Q2UR62
names: Similarity
messages: Belongs to the oxoprolinase family.

510516:AO090023000346
gene id: 510516:AO090023000346
uniprot id: Q2UHR2
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090026000203
gene id: 510516:AO090026000203
uniprot id: Q2UFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

510516:AO090009000468
gene id: 510516:AO090009000468
uniprot id: Q2UU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

510516:AO090026000380
gene id: 510516:AO090026000380
uniprot id: Q2UF23
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

510516:AO090005000086
gene id: 510516:AO090005000086
uniprot id: Q2UTB3
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

510516:AO090023000188
gene id: 510516:AO090023000188
uniprot id: Q2UI54
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000600
gene id: 510516:AO090012000600
uniprot id: Q2UCG4
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

510516:AO090005000067
gene id: 510516:AO090005000067
uniprot id: Q2UTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Secreted

510516:AO090003001207
gene id: 510516:AO090003001207
uniprot id: Q2UJH8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000997
gene id: 510516:AO090012000997
uniprot id: Q2UBH5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Lipid droplet
messages: The C-terminal 2 residues are removed by atg4 to expose Gly-116 at the C-terminus. The c-terminal Gly is then amidated with phosphatidylethanolamine by an activating system similar to that for ubiquitin.
messages: Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity). Required for both the differentiation of aerial hyphae and conidial germination (PubMed:16896216).
messages: Vacuole membrane
messages: autophagosome membrane

510516:AO090005000220
gene id: 510516:AO090005000220
uniprot id: Q2UT03
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090009000186
gene id: 510516:AO090009000186
uniprot id: Q2UUT4
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

510516:AO090102000611
gene id: 510516:AO090102000611
uniprot id: Q2U9Y9
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

510516:AO090038000194
gene id: 510516:AO090038000194
uniprot id: Q2U346
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000124
gene id: 510516:AO090001000124
uniprot id: Q2UP40
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001514
gene id: 510516:AO090005001514
uniprot id: Q2UPT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090012000983
gene id: 510516:AO090012000983
uniprot id: Q2UBI6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000321
gene id: 510516:AO090003000321
uniprot id: Q2ULP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

510516:AO090001000486
gene id: 510516:AO090001000486
uniprot id: Q2UN67
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000350
gene id: 510516:AO090012000350
uniprot id: Q2UD25
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090001000555
gene id: 510516:AO090001000555
uniprot id: Q2UN01
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

510516:AO090701000061
gene id: 510516:AO090701000061
uniprot id: Q2U9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

510516:AO090003000751
gene id: 510516:AO090003000751
uniprot id: Q2UKM3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090010000465
gene id: 510516:AO090010000465
uniprot id: Q2TWQ5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

510516:AO090102000339
gene id: 510516:AO090102000339
uniprot id: Q2UAL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

510516:AO090023000859
gene id: 510516:AO090023000859
uniprot id: Q2UGF6
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

510516:AO090005000107
gene id: 510516:AO090005000107
uniprot id: Q2UT94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

510516:AO090102000373
gene id: 510516:AO090102000373
uniprot id: Q2UAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.

510516:AO090020000055
gene id: 510516:AO090020000055
uniprot id: Q2U564
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090701000728
gene id: 510516:AO090701000728
uniprot id: Q2U7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

510516:AO090120000456
gene id: 510516:AO090120000456
uniprot id: Q2U5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

510516:AO090038000576
gene id: 510516:AO090038000576
uniprot id: Q2U272
names: Similarity
messages: Belongs to the ADIP family.

510516:AO090026000019
gene id: 510516:AO090026000019
uniprot id: Q2UFZ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090023000702
gene id: 510516:AO090023000702
uniprot id: Q2UGV0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

510516:AO090103000165
gene id: 510516:AO090103000165
uniprot id: Q2TYP5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000002
gene id: 510516:AO090026000002
uniprot id: Q2UG12
names: Similarity
messages: Belongs to the tryptophan dimethylallyltransferase family.

510516:AO090120000309
gene id: 510516:AO090120000309
uniprot id: Q2U6B3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090003000834
gene id: 510516:AO090003000834
uniprot id: Q2UKF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

510516:AO090011000346
gene id: 510516:AO090011000346
uniprot id: Q2U0Q3
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090005000672
gene id: 510516:AO090005000672
uniprot id: Q2URV8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

510516:AO090120000307
gene id: 510516:AO090120000307
uniprot id: Q2U6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

510516:AO090020000344
gene id: 510516:AO090020000344
uniprot id: Q2U4H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

510516:AO090026000028
gene id: 510516:AO090026000028
uniprot id: Q2UFY7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090003000688
gene id: 510516:AO090003000688
uniprot id: Q2UKT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

510516:AO090009000650
gene id: 510516:AO090009000650
uniprot id: Q2UTP3
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

510516:AO090011000261
gene id: 510516:AO090011000261
uniprot id: Q2U0X7
names: Similarity
messages: Belongs to the CoA-transferase III family.

510516:AO090020000083
gene id: 510516:AO090020000083
uniprot id: Q2U542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

510516:AO090010000674
gene id: 510516:AO090010000674
uniprot id: Q2TW75
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000063
gene id: 510516:AO090120000063
uniprot id: Q2U6W9
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090012000103
gene id: 510516:AO090012000103
uniprot id: Q2UDN5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

510516:AO090001000045
gene id: 510516:AO090001000045
uniprot id: Q2UPA7
names: Function
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.
messages: Dehydrogenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090001000707
gene id: 510516:AO090001000707
uniprot id: Q2UML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

510516:AO090102000543
gene id: 510516:AO090102000543
uniprot id: Q2UA50
names: Similarity
messages: Belongs to the FMO family.

510516:AO090102000142
gene id: 510516:AO090102000142
uniprot id: Q2UB23
names: Similarity
messages: Belongs to the peptidase M24 family.

510516:AO090102000375
gene id: 510516:AO090102000375
uniprot id: Q2UAI1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090009000325
gene id: 510516:AO090009000325
uniprot id: Q2UUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

510516:AO090701000860
gene id: 510516:AO090701000860
uniprot id: Q2U7F5
names: Similarity
messages: Belongs to the peptidase M28 family.

510516:AO090138000104
gene id: 510516:AO090138000104
uniprot id: Q2U1T5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000168
gene id: 510516:AO090701000168
uniprot id: Q2U954
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

510516:AO090003001508
gene id: 510516:AO090003001508
uniprot id: Q2UIR6
names: Similarity
messages: Belongs to the hexokinase family.

510516:AO090701000149
gene id: 510516:AO090701000149
uniprot id: Q2U968
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity).

510516:AO090206000115
gene id: 510516:AO090206000115
uniprot id: Q2PIQ0
names: Similarity
messages: Belongs to the AFG1 ATPase family.

510516:AO090023000309
gene id: 510516:AO090023000309
uniprot id: Q2UHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090003000261
gene id: 510516:AO090003000261
uniprot id: Q2ULU8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090701000058
gene id: 510516:AO090701000058
uniprot id: Q2U9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090011000308
gene id: 510516:AO090011000308
uniprot id: Q2U0T9
names: Similarity
messages: Belongs to the glutamine synthetase family.

510516:AO090003000042
gene id: 510516:AO090003000042
uniprot id: Q2UMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 35 family.
messages: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
messages: Secreted

510516:AO090012000033
gene id: 510516:AO090012000033
uniprot id: Q2UDT8
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090005001624
gene id: 510516:AO090005001624
uniprot id: Q2UPI8
names: Similarity
messages: Belongs to the WD repeat rae1 family.

510516:AO090701000321
gene id: 510516:AO090701000321
uniprot id: Q2U8R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).
messages: Secreted

510516:AO090102000358
gene id: 510516:AO090102000358
uniprot id: Q2UAJ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

510516:AO090020000270
gene id: 510516:AO090020000270
uniprot id: Q2U4N3
names: Similarity
messages: Belongs to the FAH family.

510516:AO090005000767
gene id: 510516:AO090005000767
uniprot id: Q2URM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

510516:AO090120000281
gene id: 510516:AO090120000281
uniprot id: Q2U6D8
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

510516:AO090020000504
gene id: 510516:AO090020000504
uniprot id: Q2U440
names: Similarity
messages: Belongs to the thioredoxin family.

510516:AO090102000389
gene id: 510516:AO090102000389
uniprot id: Q2UAH0
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

510516:AO090023000709
gene id: 510516:AO090023000709
uniprot id: Q2UGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

510516:AO090003001300
gene id: 510516:AO090003001300
uniprot id: Q2UJA2
names: Similarity
messages: Belongs to the peptidase S33 family.

510516:AO090009000291
gene id: 510516:AO090009000291
uniprot id: Q2UUJ5
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

510516:AO090103000225
gene id: 510516:AO090103000225
uniprot id: Q2TYI9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090026000634
gene id: 510516:AO090026000634
uniprot id: Q2UEF9
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

510516:AO090009000488
gene id: 510516:AO090009000488
uniprot id: Q2UU23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

510516:AO090012000452
gene id: 510516:AO090012000452
uniprot id: Q2UCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

510516:AO090003000765
gene id: 510516:AO090003000765
uniprot id: Q2UKK9
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090001000748
gene id: 510516:AO090001000748
uniprot id: Q2UMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

510516:AO090003000090
gene id: 510516:AO090003000090
uniprot id: Q9UUZ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-216 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

510516:AO090001000257
gene id: 510516:AO090001000257
uniprot id: Q2UNR9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090012000865
gene id: 510516:AO090012000865
uniprot id: Q2UBU1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

510516:AO090001000709
gene id: 510516:AO090001000709
uniprot id: Q2UML6
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

510516:AO090001000627
gene id: 510516:AO090001000627
uniprot id: Q2UMT9
names: Domain
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. YAP subfamily.
messages: Contains two cysteine rich domains (CRD), referred to as the N- and C-terminal CRD's, n-CRD and c-CRD, respectively. A nuclear export signal is embedded in the c-CRD, with which the nuclear export proteins interact only in the absence of disulfide bonds (or otherwise oxidized cysteines) within the c-CRD or between the c-CRD and the n-CRD.
messages: Cytoplasm
messages: Depending on the oxidative stress inducing agent, yap1 can undergo two distinct conformational changes, both involving disulfide bond formation, and both masking the nuclear export signal, thus abolishing nuclear export.
messages: Expression is enhanced upon oxidative stress stimuli.
messages: Nucleus
messages: Transcription activator involved in oxidative stress response and redox homeostasis (PubMed:31366149). Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways (By similarity).

510516:AO090120000001
gene id: 510516:AO090120000001
uniprot id: Q2U724
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

510516:AO090003001290
gene id: 510516:AO090003001290
uniprot id: Q2UJB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090023000410
gene id: 510516:AO090023000410
uniprot id: Q2UHK6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000202
gene id: 510516:AO090005000202
uniprot id: Q2UT17
names: Similarity
messages: Belongs to the DapA family.

510516:AO090103000359
gene id: 510516:AO090103000359
uniprot id: Q2TY79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003001057
gene id: 510516:AO090003001057
uniprot id: Q2UJV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

510516:AO090005001456
gene id: 510516:AO090005001456
uniprot id: Q2UPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

510516:AO090701000815
gene id: 510516:AO090701000815
uniprot id: Q2U7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090701000220
gene id: 510516:AO090701000220
uniprot id: Q2U908
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090012000706
gene id: 510516:AO090012000706
uniprot id: Q2UC77
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090102000157
gene id: 510516:AO090102000157
uniprot id: Q2UB09
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

510516:AO090701000066
gene id: 510516:AO090701000066
uniprot id: Q2U9E0
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

510516:AO090103000235
gene id: 510516:AO090103000235
uniprot id: Q2TYI1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000622
gene id: 510516:AO090701000622
uniprot id: Q2U804
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090020000594
gene id: 510516:AO090020000594
uniprot id: Q2U3W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

510516:AO090701000095
gene id: 510516:AO090701000095
uniprot id: Q2U9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

510516:AO090011000712
gene id: 510516:AO090011000712
uniprot id: Q2TZU9
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003000257
gene id: 510516:AO090003000257
uniprot id: Q2ULV1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

510516:AO090011000363
gene id: 510516:AO090011000363
uniprot id: Q2U0N7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090206000105
gene id: 510516:AO090206000105
uniprot id: Q2PIQ9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

510516:AO090103000268
gene id: 510516:AO090103000268
uniprot id: Q2TYF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090011000780
gene id: 510516:AO090011000780
uniprot id: Q2TZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

510516:AO090701000511
gene id: 510516:AO090701000511
uniprot id: Q2U8A2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090020000684
gene id: 510516:AO090020000684
uniprot id: Q2U3N8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090701000119
gene id: 510516:AO090701000119
uniprot id: Q2U997
names: Similarity
messages: Belongs to the CWC21 family.

510516:AO090020000328
gene id: 510516:AO090020000328
uniprot id: Q2U4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090005001412
gene id: 510516:AO090005001412
uniprot id: Q2UQ28
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

510516:AO090003001545
gene id: 510516:AO090003001545
uniprot id: Q2UIN6
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090026000590
gene id: 510516:AO090026000590
uniprot id: Q2UEJ7
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

510516:AO090103000127
gene id: 510516:AO090103000127
uniprot id: Q2TYS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

510516:AO090001000585
gene id: 510516:AO090001000585
uniprot id: Q2UMX3
names: Subcellular Location Annotation
names: Subunit
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Membrane

510516:AO090206000124
gene id: 510516:AO090206000124
uniprot id: Q2PIP2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

510516:AO090012000349
gene id: 510516:AO090012000349
uniprot id: Q2UD26
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090102000609
gene id: 510516:AO090102000609
uniprot id: Q2U9Z1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090009000559
gene id: 510516:AO090009000559
uniprot id: Q2UTX0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090001000708
gene id: 510516:AO090001000708
uniprot id: Q2UML7
names: Similarity
messages: Belongs to the COG4 family.

510516:AO090102000094
gene id: 510516:AO090102000094
uniprot id: Q2UB63
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000538
gene id: 510516:AO090011000538
uniprot id: Q2U091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090001000468
gene id: 510516:AO090001000468
uniprot id: Q2UN82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

510516:AO090011000488
gene id: 510516:AO090011000488
uniprot id: Q2U0D1
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

510516:AO090701000334
gene id: 510516:AO090701000334
uniprot id: Q2U8Q6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

510516:AO090124000035
gene id: 510516:AO090124000035
uniprot id: Q2U779
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000883
gene id: 510516:AO090012000883
uniprot id: Q2UBS7
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090003001233
gene id: 510516:AO090003001233
uniprot id: Q2UJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

510516:AO090102000401
gene id: 510516:AO090102000401
uniprot id: Q2UAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

510516:AO090012000100
gene id: 510516:AO090012000100
uniprot id: Q2UDN8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

510516:AO090120000207
gene id: 510516:AO090120000207
uniprot id: Q2U6J7
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090701000351
gene id: 510516:AO090701000351
uniprot id: Q2U8P0
names: Similarity
messages: Belongs to the PPP phosphatase family.

510516:AO090009000289
gene id: 510516:AO090009000289
uniprot id: Q2UUJ7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

510516:AO090011000456
gene id: 510516:AO090011000456
uniprot id: Q2U0F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

510516:AO090001000162
gene id: 510516:AO090001000162
uniprot id: Q2UP04
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090005001589
gene id: 510516:AO090005001589
uniprot id: Q2UPM1
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090023000754
gene id: 510516:AO090023000754
uniprot id: Q2UGQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090011000458
gene id: 510516:AO090011000458
uniprot id: Q2U0F6
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090009000219
gene id: 510516:AO090009000219
uniprot id: Q2UUQ5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

510516:AO090010000475
gene id: 510516:AO090010000475
uniprot id: Q2TWP6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

510516:AO090011000323
gene id: 510516:AO090011000323
uniprot id: Q2U0S6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090026000739
gene id: 510516:AO090026000739
uniprot id: Q2UE71
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003001250
gene id: 510516:AO090003001250
uniprot id: Q2UJE5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090120000474
gene id: 510516:AO090120000474
uniprot id: Q06902
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Inhibited by sodium lauryl sulfonate.
messages: Secreted
messages: Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates. The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site. Shows a broad primary substrate specificity. Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A. Hydrolyzes bovine chymotrysinogen A between positions 'Arg-15' and 'Ile-16'.
messages: Two isozymes of this enzyme exist which differ only by their non-covalent association with carbohydrate.

510516:AO090103000149
gene id: 510516:AO090103000149
uniprot id: Q2TYQ8
names: Similarity
messages: Belongs to the GST superfamily.

510516:AO090026000267
gene id: 510516:AO090026000267
uniprot id: Q2UFB7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

510516:AO090120000283
gene id: 510516:AO090120000283
uniprot id: Q2U6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

510516:AO090001000026
gene id: 510516:AO090001000026
uniprot id: Q2UPC5
names: Function
names: Similarity
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090003000855
gene id: 510516:AO090003000855
uniprot id: Q2UKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

510516:AO090026000184
gene id: 510516:AO090026000184
uniprot id: Q2UFJ4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

510516:AO090138000121
gene id: 510516:AO090138000121
uniprot id: Q2U1R9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090026000725
gene id: 510516:AO090026000725
uniprot id: Q2UE84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003000676
gene id: 510516:AO090003000676
uniprot id: Q2UKU1
names: Similarity
messages: Belongs to the RMD1/sif2 family.

510516:AO090010000079
gene id: 510516:AO090010000079
uniprot id: Q2TXN1
names: Similarity
messages: Belongs to the Gfa family.

510516:AO090166000050
gene id: 510516:AO090166000050
uniprot id: Q2U9R3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090012000710
gene id: 510516:AO090012000710
uniprot id: Q2UC75
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000385
gene id: 510516:AO090012000385
uniprot id: Q2UCZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003001337
gene id: 510516:AO090003001337
uniprot id: Q2UJ68
names: Similarity
messages: Belongs to the activator 1 small subunits family.

510516:AO090020000571
gene id: 510516:AO090020000571
uniprot id: Q2U3Y2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

510516:AO090120000500
gene id: 510516:AO090120000500
uniprot id: Q2U5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

510516:AO090103000383
gene id: 510516:AO090103000383
uniprot id: Q2TY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090020000342
gene id: 510516:AO090020000342
uniprot id: Q2U4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

510516:AO090020000035
gene id: 510516:AO090020000035
uniprot id: Q2U583
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

510516:AO090166000070
gene id: 510516:AO090166000070
uniprot id: Q2U9P4
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000506
gene id: 510516:AO090011000506
uniprot id: Q2U0B5
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

510516:AO090003000497
gene id: 510516:AO090003000497
uniprot id: Q2UL94
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

510516:AO090026000740
gene id: 510516:AO090026000740
uniprot id: Q2UE70
names: Similarity
messages: Belongs to the DapA family.

510516:AO090010000644
gene id: 510516:AO090010000644
uniprot id: Q2TWA0
names: Similarity
messages: Belongs to the peptidase A1 family.

510516:AO090038000594
gene id: 510516:AO090038000594
uniprot id: Q2U256
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

510516:AO090005000807
gene id: 510516:AO090005000807
uniprot id: Q2URJ2
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

510516:AO090011000790
gene id: 510516:AO090011000790
uniprot id: Q2TZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

510516:AO090003001225
gene id: 510516:AO090003001225
uniprot id: Q2UJG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 47 family.
messages: Cytoplasmic vesicle lumen
messages: Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
messages: Monomer.

510516:AO090005000860
gene id: 510516:AO090005000860
uniprot id: Q2URE6
names: Similarity
messages: Belongs to the FAH family.

510516:AO090038000057
gene id: 510516:AO090038000057
uniprot id: Q2U3F8
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090102000135
gene id: 510516:AO090102000135
uniprot id: Q2UB29
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000702
gene id: 510516:AO090026000702
uniprot id: Q2UEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

510516:AO090023001001
gene id: 510516:AO090023001001
uniprot id: Q2UG29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

510516:AO090010000011
gene id: 510516:AO090010000011
uniprot id: Q2TXU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000933
gene id: 510516:AO090011000933
uniprot id: Q2TZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090020000240
gene id: 510516:AO090020000240
uniprot id: Q2U4Q8
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090009000502
gene id: 510516:AO090009000502
uniprot id: O13415
names: Function
names: Subcellular Location Annotation
messages: Major nitrogen regulatory protein. Positively acting regulatory gene of nitrogen metabolite repression.
messages: Nucleus

510516:AO090005000695
gene id: 510516:AO090005000695
uniprot id: Q2URT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.
messages: Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).
messages: Nucleus

510516:AO090003000798
gene id: 510516:AO090003000798
uniprot id: Q2UKI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090003000424
gene id: 510516:AO090003000424
uniprot id: Q2ULG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.
messages: Cytoplasm
messages: Homodimer. May form higher order oligomers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090003001339
gene id: 510516:AO090003001339
uniprot id: Q2UJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

510516:AO090701000197
gene id: 510516:AO090701000197
uniprot id: Q2U927
names: Similarity
messages: Belongs to the UPF0235 family.

510516:AO090003000554
gene id: 510516:AO090003000554
uniprot id: Q2UL45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.
messages: Nucleus
messages: kinetochore

510516:AO090026000414
gene id: 510516:AO090026000414
uniprot id: Q2UEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

510516:AO090012000813
gene id: 510516:AO090012000813
uniprot id: Q2UBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis.

510516:AO090020000202
gene id: 510516:AO090020000202
uniprot id: Q2U4U4
names: Similarity
messages: Belongs to the PPC synthetase family.

510516:AO090003000401
gene id: 510516:AO090003000401
uniprot id: Q2ULI2
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

510516:AO090120000326
gene id: 510516:AO090120000326
uniprot id: Q2U697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

510516:AO090005001627
gene id: 510516:AO090005001627
uniprot id: Q2UPI5
names: Similarity
messages: Belongs to the MYG1 family.

510516:AO090011000038
gene id: 510516:AO090011000038
uniprot id: Q2U1G5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090038000451
gene id: 510516:AO090038000451
uniprot id: Q2U2H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

510516:AO090012000934
gene id: 510516:AO090012000934
uniprot id: Q2UBN0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

510516:AO090003001507
gene id: 510516:AO090003001507
uniprot id: Q2UIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

510516:AO090005000428
gene id: 510516:AO090005000428
uniprot id: Q2USH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm
messages: Membrane

510516:AO090026000449
gene id: 510516:AO090026000449
uniprot id: Q2UEW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

510516:AO090020000472
gene id: 510516:AO090020000472
uniprot id: Q2U465
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090012000676
gene id: 510516:AO090012000676
uniprot id: Q2UCA3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

510516:AO090026000440
gene id: 510516:AO090026000440
uniprot id: Q2UEX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.
messages: Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.
messages: Component of the SCF(sconB) E3 ubiquitin ligase complex.

510516:AO090010000232
gene id: 510516:AO090010000232
uniprot id: Q2TX95
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090009000303
gene id: 510516:AO090009000303
uniprot id: Q2UUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

510516:AO090701000452
gene id: 510516:AO090701000452
uniprot id: Q2U8F3
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003001404
gene id: 510516:AO090003001404
uniprot id: Q2UJ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

510516:AO090009000333
gene id: 510516:AO090009000333
uniprot id: Q2UUF7
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

510516:AO090012000154
gene id: 510516:AO090012000154
uniprot id: Q2UDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

510516:AO090020000415
gene id: 510516:AO090020000415
uniprot id: Q2U4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

510516:AO090020000024
gene id: 510516:AO090020000024
uniprot id: Q2U594
names: Similarity
messages: Belongs to the OSBP family.

510516:AO090026000426
gene id: 510516:AO090026000426
uniprot id: Q2UEY6
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090005001123
gene id: 510516:AO090005001123
uniprot id: Q2UQS3
names: Similarity
messages: Belongs to the APC10 family.

510516:AO090023000159
gene id: 510516:AO090023000159
uniprot id: Q2UI80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090113000139
gene id: 510516:AO090113000139
uniprot id: Q2U5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090003000175
gene id: 510516:AO090003000175
uniprot id: Q2UM21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090020000484
gene id: 510516:AO090020000484
uniprot id: Q2U457
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

510516:AO090138000008
gene id: 510516:AO090138000008
uniprot id: Q2U216
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

510516:AO090020000219
gene id: 510516:AO090020000219
uniprot id: Q2U4S7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000649
gene id: 510516:AO090020000649
uniprot id: Q2U3R6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000141
gene id: 510516:AO090001000141
uniprot id: Q2UP25
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000099
gene id: 510516:AO090701000099
uniprot id: Q2U9B3
names: Similarity
messages: Belongs to the MNN1/MNT family.

510516:AO090001000032
gene id: 510516:AO090001000032
uniprot id: Q2UPC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ABC transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Membrane

510516:AO090005000134
gene id: 510516:AO090005000134
uniprot id: Q2UT70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
messages: Heterodimer consisting of msh2-msh3 (MutS beta). Forms a ternary complex with MutL alpha (mlh1-pms1) (By similarity).
messages: Nucleus

510516:AO090009000213
gene id: 510516:AO090009000213
uniprot id: Q2UUR1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000685
gene id: 510516:AO090023000685
uniprot id: Q2UGW4
names: Function
names: Similarity
messages: Belongs to the lysophospholipase family.
messages: Catalyzes the release of fatty acids from lysophospholipids.

510516:AO090003001034
gene id: 510516:AO090003001034
uniprot id: Q2UJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

510516:AO090003000490
gene id: 510516:AO090003000490
uniprot id: Q2ULA1
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090701000028
gene id: 510516:AO090701000028
uniprot id: Q2U9H6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

510516:AO090005001099
gene id: 510516:AO090005001099
uniprot id: Q2UQU3
names: Similarity
messages: Belongs to the peptidase C12 family.

510516:AO090023000209
gene id: 510516:AO090023000209
uniprot id: Q2UI33
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

510516:AO090102000290
gene id: 510516:AO090102000290
uniprot id: Q2UAQ2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.

510516:AO090003000500
gene id: 510516:AO090003000500
uniprot id: Q2UL92
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

510516:AO090166000101
gene id: 510516:AO090166000101
uniprot id: Q2U9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus
messages: Probable regulator of conidiophore development and conidium maturation (By similarity).

510516:AO090012000488
gene id: 510516:AO090012000488
uniprot id: Q2UCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

510516:AO090005001478
gene id: 510516:AO090005001478
uniprot id: Q2UPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

510516:AO090020000564
gene id: 510516:AO090020000564
uniprot id: Q2U3Y7
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090011000622
gene id: 510516:AO090011000622
uniprot id: Q2U020
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

510516:AO090120000125
gene id: 510516:AO090120000125
uniprot id: Q2U6R6
names: Similarity
messages: Belongs to the peptidase C19 family.

510516:AO090026000544
gene id: 510516:AO090026000544
uniprot id: Q2UEP0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

510516:AO090003000208
gene id: 510516:AO090003000208
uniprot id: Q2ULZ5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

510516:AO090010000169
gene id: 510516:AO090010000169
uniprot id: Q2TXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: MFS-type transporter; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone.
messages: Membrane

510516:AO090023000411
gene id: 510516:AO090023000411
uniprot id: Q2UHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

510516:AO090138000175
gene id: 510516:AO090138000175
uniprot id: Q2U1M1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000055
gene id: 510516:AO090120000055
uniprot id: Q2U6X5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

510516:AO090038000344
gene id: 510516:AO090038000344
uniprot id: Q2U2S0
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

510516:AO090010000339
gene id: 510516:AO090010000339
uniprot id: Q2TX04
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

510516:AO090001000214
gene id: 510516:AO090001000214
uniprot id: Q2UNV8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

510516:AO090020000634
gene id: 510516:AO090020000634
uniprot id: Q2U3S8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

510516:AO090012000251
gene id: 510516:AO090012000251
uniprot id: Q2UDA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090010000504
gene id: 510516:AO090010000504
uniprot id: Q2TWM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.
messages: Secreted

510516:AO090701000543
gene id: 510516:AO090701000543
uniprot id: Q2U874
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

510516:AO090103000037
gene id: 510516:AO090103000037
uniprot id: Q2TZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

510516:AO090003000193
gene id: 510516:AO090003000193
uniprot id: Q2UM06
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

510516:AO090113000148
gene id: 510516:AO090113000148
uniprot id: Q2U5G8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

510516:AO090023000957
gene id: 510516:AO090023000957
uniprot id: Q2UG69
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

510516:AO090005001340
gene id: 510516:AO090005001340
uniprot id: Q2UQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Cytoplasm
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).
messages: Nucleus

510516:AO090012000786
gene id: 510516:AO090012000786
uniprot id: Q2UC14
names: Function
names: Similarity
messages: Belongs to the POA1 family.
messages: Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.

510516:AO090003001305
gene id: 510516:AO090003001305
uniprot id: Q2UJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
messages: Secreted

510516:AO090103000403
gene id: 510516:AO090103000403
uniprot id: Q2TY39
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

510516:AO090672000009
gene id: 510516:AO090672000009
uniprot id: Q2UG14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

510516:AO090120000437
gene id: 510516:AO090120000437
uniprot id: Q2U600
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Cytoplasm
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

510516:AO090020000640
gene id: 510516:AO090020000640
uniprot id: Q2U3S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

510516:AO090701000162
gene id: 510516:AO090701000162
uniprot id: Q2U959
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001277
gene id: 510516:AO090003001277
uniprot id: Q2UJC4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090026000516
gene id: 510516:AO090026000516
uniprot id: O94183
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Cytoplasm
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Monomer.

510516:AO090001000145
gene id: 510516:AO090001000145
uniprot id: Q2UP21
names: Similarity
messages: Belongs to the peptidase M28 family.

510516:AO090001000154
gene id: 510516:AO090001000154
uniprot id: Q2UP12
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090005000716
gene id: 510516:AO090005000716
uniprot id: Q2URR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

510516:AO090011000860
gene id: 510516:AO090011000860
uniprot id: Q2TZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090010000036
gene id: 510516:AO090010000036
uniprot id: Q2TXR8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090206000110
gene id: 510516:AO090206000110
uniprot id: Q2PIQ5
names: Similarity
messages: Belongs to the RutC family.

510516:AO090005000158
gene id: 510516:AO090005000158
uniprot id: Q2UT49
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

510516:AO090120000091
gene id: 510516:AO090120000091
uniprot id: Q2U6U5
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

510516:AO090001000490
gene id: 510516:AO090001000490
uniprot id: Q2UN63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

510516:AO090026000382
gene id: 510516:AO090026000382
uniprot id: Q2UF21
names: Similarity
messages: Belongs to the trichodiene synthase family.

510516:AO090020000425
gene id: 510516:AO090020000425
uniprot id: Q2U4A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

510516:AO090012000653
gene id: 510516:AO090012000653
uniprot id: Q2UCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

510516:AO090003001495
gene id: 510516:AO090003001495
uniprot id: Q2UIS8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090120000316
gene id: 510516:AO090120000316
uniprot id: Q2U6A7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

510516:AO090005000972
gene id: 510516:AO090005000972
uniprot id: Q2UR48
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

510516:AO090009000594
gene id: 510516:AO090009000594
uniprot id: Q2UTU0
names: Similarity
messages: Belongs to the LTV1 family.

510516:AO090003000068
gene id: 510516:AO090003000068
uniprot id: Q2UMB2
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090005001291
gene id: 510516:AO090005001291
uniprot id: Q2UQD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules.
messages: nucleolus

510516:AO090120000433
gene id: 510516:AO090120000433
uniprot id: Q2U604
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090120000280
gene id: 510516:AO090120000280
uniprot id: Q2U6D9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

510516:AO090005000962
gene id: 510516:AO090005000962
uniprot id: Q2UR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090010000466
gene id: 510516:AO090010000466
uniprot id: Q2TWQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

510516:AO090010000165
gene id: 510516:AO090010000165
uniprot id: Q2TXF6
names: Function
messages: Ankyrin repeat domain-containing protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).

510516:AO090012000205
gene id: 510516:AO090012000205
uniprot id: Q2UDE4
names: Similarity
messages: Belongs to the HMBS family.

510516:AO090005001095
gene id: 510516:AO090005001095
uniprot id: Q2UQU7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000073
gene id: 510516:AO090005000073
uniprot id: Q2UTC6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090038000578
gene id: 510516:AO090038000578
uniprot id: Q2U270
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

510516:AO090001000091
gene id: 510516:AO090001000091
uniprot id: Q2UP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

510516:AO090138000195
gene id: 510516:AO090138000195
uniprot id: Q2U1K9
names: Similarity
messages: Belongs to the isochorismatase family.

510516:AO090010000471
gene id: 510516:AO090010000471
uniprot id: Q2TWQ0
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

510516:AO090020000203
gene id: 510516:AO090020000203
uniprot id: Q2U4U3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000225
gene id: 510516:AO090023000225
uniprot id: Q2UI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

510516:AO090005001300
gene id: 510516:AO090005001300
uniprot id: Q2UQD0
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

510516:AO090010000620
gene id: 510516:AO090010000620
uniprot id: Q2TWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

510516:AO090003000913
gene id: 510516:AO090003000913
uniprot id: Q2UK85
names: Similarity
messages: Belongs to the SEC3 family.

510516:AO090005000690
gene id: 510516:AO090005000690
uniprot id: Q2URU1
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090012000647
gene id: 510516:AO090012000647
uniprot id: Q2UCC6
names: Similarity
messages: Belongs to the KTI12 family.

510516:AO090005000576
gene id: 510516:AO090005000576
uniprot id: Q2US45
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Phosphorylation of the TEDS site (Ser-370) is required for the polarization of the actin cytoskeleton. Phosphorylation probably activates the myosin-I ATPase activity (By similarity).
messages: The myosin motor domain displays actin-stimulated ATPase activity and generates a mechanochemical force.
messages: The tail domain participates in molecular interactions that specify the role of the motor domain (By similarity). It is composed of several tail homology (TH) domains, namely a putative phospholipid-binding myosin tail domain (also named TH1), an Ala- and Pro-rich domain (TH2), followed by an SH3 domain and a C-terminal acidic domain (TH3).
messages: Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
messages: actin patch

510516:AO090103000360
gene id: 510516:AO090103000360
uniprot id: Q2TY78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090003001432
gene id: 510516:AO090003001432
uniprot id: Q2UIX9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

510516:AO090038000507
gene id: 510516:AO090038000507
uniprot id: Q2U2C6
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090003000404
gene id: 510516:AO090003000404
uniprot id: Q2ULH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

510516:AO090003001387
gene id: 510516:AO090003001387
uniprot id: Q2UJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090026000338
gene id: 510516:AO090026000338
uniprot id: Q2UF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

510516:AO090009000552
gene id: 510516:AO090009000552
uniprot id: Q2UTX7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000714
gene id: 510516:AO090001000714
uniprot id: Q2UML1
names: Function
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family.
messages: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.

510516:AO090003000454
gene id: 510516:AO090003000454
uniprot id: Q2ULD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

510516:AO090701000490
gene id: 510516:AO090701000490
uniprot id: Q2U8B9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090023000750
gene id: 510516:AO090023000750
uniprot id: Q2UGR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090103000329
gene id: 510516:AO090103000329
uniprot id: Q2TYA4
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

510516:AO090005001241
gene id: 510516:AO090005001241
uniprot id: Q2UQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSH4 family.
messages: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.
messages: Endosome membrane
messages: Membrane
messages: Vacuole membrane

510516:AO090009000516
gene id: 510516:AO090009000516
uniprot id: Q2UU05
names: Similarity
messages: Belongs to the FMO family.

510516:AO090038000365
gene id: 510516:AO090038000365
uniprot id: Q2U2Q1
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090012000932
gene id: 510516:AO090012000932
uniprot id: Q2UBN2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.

510516:AO090026000584
gene id: 510516:AO090026000584
uniprot id: Q2UEK3
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: Impairs the production of trihydroxy confertifolin and deacetyl astellolides A and B.

510516:AO090102000639
gene id: 510516:AO090102000639
uniprot id: Q2U9W4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

510516:AO090038000175
gene id: 510516:AO090038000175
uniprot id: Q2U360
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

510516:AO090023000050
gene id: 510516:AO090023000050
uniprot id: Q2UIH8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090012000298
gene id: 510516:AO090012000298
uniprot id: Q2UD66
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

510516:AO090003000325
gene id: 510516:AO090003000325
uniprot id: Q2ULP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090009000068
gene id: 510516:AO090009000068
uniprot id: Q2UV31
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000639
gene id: 510516:AO090005000639
uniprot id: Q2URY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

510516:AO090701000748
gene id: 510516:AO090701000748
uniprot id: Q2U7Q3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

510516:AO090001000408
gene id: 510516:AO090001000408
uniprot id: Q2UND6
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090005000038
gene id: 510516:AO090005000038
uniprot id: Q2UTF6
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090038000119
gene id: 510516:AO090038000119
uniprot id: Q2U3A6
names: Similarity
messages: Belongs to the peptidase S33 family.

510516:AO090026000599
gene id: 510516:AO090026000599
uniprot id: Q2UEJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

510516:AO090120000495
gene id: 510516:AO090120000495
uniprot id: Q2U5V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

510516:AO090009000330
gene id: 510516:AO090009000330
uniprot id: Q2UUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

510516:AO090102000146
gene id: 510516:AO090102000146
uniprot id: Q2UB20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane

510516:AO090003001139
gene id: 510516:AO090003001139
uniprot id: Q2UJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

510516:AO090001000736
gene id: 510516:AO090001000736
uniprot id: Q2UMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

510516:AO090023000944
gene id: 510516:AO090023000944
uniprot id: P0C1B3
names: Biotechnology
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Binds 2 calcium ions per subunit (PubMed:6609921, PubMed:9283074, PubMed:16880540). Calcium is inhibitory at high concentrations.
messages: Monomer.
messages: Secreted
messages: Used in the brewing industry to increase the fermentability of beer worts (including those made from unmalted cereals), in the starch industry to make high maltose and high DE syrups (starch saccharification), in the alcohol industry to reduce fermentation time, in the cereal food industry for flour supplementation and improvement of chilled and frozen dough, and in the forestry industry for low-temperature modification of starch. Sold under the name Fungamyl by Novozymes.

510516:AO090038000540
gene id: 510516:AO090038000540
uniprot id: Q2U2A4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

510516:AO090003000403
gene id: 510516:AO090003000403
uniprot id: Q2ULI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex, and the protein sar1. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.

510516:AO090009000217
gene id: 510516:AO090009000217
uniprot id: Q2UUQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090026000551
gene id: 510516:AO090026000551
uniprot id: Q2UEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

510516:AO090010000067
gene id: 510516:AO090010000067
uniprot id: Q2TXP3
names: Similarity
messages: Belongs to the proline racemase family.

510516:AO090120000245
gene id: 510516:AO090120000245
uniprot id: Q2U6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090003000572
gene id: 510516:AO090003000572
uniprot id: Q2UL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

510516:AO090026000811
gene id: 510516:AO090026000811
uniprot id: Q2UE04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

510516:AO090010000722
gene id: 510516:AO090010000722
uniprot id: Q2TW34
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.
messages: Cytoplasm
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

510516:AO090005001518
gene id: 510516:AO090005001518
uniprot id: Q2UPT4
names: Similarity
messages: Belongs to the cyclin family.

510516:AO090010000769
gene id: 510516:AO090010000769
uniprot id: Q2TVY7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family.
messages: Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.
messages: Present with 7210 molecules/cell in log phase SD medium.
messages: Prevacuolar compartment membrane
messages: The lumenal domain contains two regions of approximately 650 AA that exhibit 20% identity. The cytoplasmic domain may serve as a Golgi retention/recycling signal.
messages: trans-Golgi network membrane

510516:AO090012000526
gene id: 510516:AO090012000526
uniprot id: Q2UCM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

510516:AO090038000135
gene id: 510516:AO090038000135
uniprot id: Q2U391
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

510516:AO090010000746
gene id: 510516:AO090010000746
uniprot id: P36914
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

510516:AO090003001296
gene id: 510516:AO090003001296
uniprot id: Q2UJA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090001000038
gene id: 510516:AO090001000038
uniprot id: Q2UPB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Thioredoxin reductase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090011000806
gene id: 510516:AO090011000806
uniprot id: Q2TZL4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000261
gene id: 510516:AO090012000261
uniprot id: Q2UD99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

510516:AO090120000399
gene id: 510516:AO090120000399
uniprot id: Q2U634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

510516:AO090102000593
gene id: 510516:AO090102000593
uniprot id: Q2UA05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

510516:AO090102000081
gene id: 510516:AO090102000081
uniprot id: Q2UB74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090026000787
gene id: 510516:AO090026000787
uniprot id: Q2UE25
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

510516:AO090012000295
gene id: 510516:AO090012000295
uniprot id: Q2UD69
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000106
gene id: 510516:AO090023000106
uniprot id: Q2UID0
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090023000083
gene id: 510516:AO090023000083
uniprot id: Q2UIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 16 family.
messages: Cell membrane
messages: Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates.

510516:AO090012000389
gene id: 510516:AO090012000389
uniprot id: Q2UCZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

510516:AO090011000607
gene id: 510516:AO090011000607
uniprot id: Q2U033
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

510516:AO090038000550
gene id: 510516:AO090038000550
uniprot id: Q2U295
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090003000831
gene id: 510516:AO090003000831
uniprot id: Q2UKF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

510516:AO090003001162
gene id: 510516:AO090003001162
uniprot id: Q2UJL5
names: Similarity
messages: Belongs to the SEC6 family.

510516:AO090026000576
gene id: 510516:AO090026000576
uniprot id: Q2UEL0
names: Function
names: Induction
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: Sesquiterpene phosphatase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).

510516:AO090011000768
gene id: 510516:AO090011000768
uniprot id: Q2TZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090010000098
gene id: 510516:AO090010000098
uniprot id: Q2TXL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090020000041
gene id: 510516:AO090020000041
uniprot id: Q2U577
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

510516:AO090005000367
gene id: 510516:AO090005000367
uniprot id: Q2USM5
names: Function
names: Similarity
messages: Belongs to the choline monooxygenase family.
messages: Catalyzes the first step of the osmoprotectant glycine betaine synthesis.

510516:AO090003000697
gene id: 510516:AO090003000697
uniprot id: Q2UKS1
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

510516:AO090103000336
gene id: 510516:AO090103000336
uniprot id: Q2TY97
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090001000484
gene id: 510516:AO090001000484
uniprot id: Q2UN69
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

510516:AO090005000551
gene id: 510516:AO090005000551
uniprot id: Q2US66
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

510516:AO090003001144
gene id: 510516:AO090003001144
uniprot id: Q2UJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

510516:AO090020000552
gene id: 510516:AO090020000552
uniprot id: Q2U3Z8
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

510516:AO090026000523
gene id: 510516:AO090026000523
uniprot id: Q2UEQ6
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family.

510516:AO090005000604
gene id: 510516:AO090005000604
uniprot id: Q2US19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

510516:AO090023000816
gene id: 510516:AO090023000816
uniprot id: Q2UGJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

510516:AO090001000034
gene id: 510516:AO090001000034
uniprot id: Q2UPB8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090003000164
gene id: 510516:AO090003000164
uniprot id: Q2UM29
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

510516:AO090103000020
gene id: 510516:AO090103000020
uniprot id: Q2TZ16
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

510516:AO090023000551
gene id: 510516:AO090023000551
uniprot id: Q2UH81
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090038000370
gene id: 510516:AO090038000370
uniprot id: Q2U2P7
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

510516:AO090011000679
gene id: 510516:AO090011000679
uniprot id: Q2TZX5
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

510516:AO090020000096
gene id: 510516:AO090020000096
uniprot id: Q2U532
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090001000547
gene id: 510516:AO090001000547
uniprot id: Q2UN09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

510516:AO090038000425
gene id: 510516:AO090038000425
uniprot id: Q2U2K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

510516:AO090009000228
gene id: 510516:AO090009000228
uniprot id: Q2UUQ0
names: Similarity
messages: Belongs to the peptidase A1 family.

510516:AO090005000219
gene id: 510516:AO090005000219
uniprot id: Q2UT04
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090023000542
gene id: 510516:AO090023000542
uniprot id: Q2UH88
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

510516:AO090005000698
gene id: 510516:AO090005000698
uniprot id: Q2URT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090005000033
gene id: 510516:AO090005000033
uniprot id: Q2UTG1
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090005000850
gene id: 510516:AO090005000850
uniprot id: Q2URF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090003001121
gene id: 510516:AO090003001121
uniprot id: Q2UJQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090026000103
gene id: 510516:AO090026000103
uniprot id: Q2UFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.
messages: Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
messages: Secreted

510516:AO090012000434
gene id: 510516:AO090012000434
uniprot id: Q2UCV3
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

510516:AO090023000719
gene id: 510516:AO090023000719
uniprot id: Q2UGT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

510516:AO090005001183
gene id: 510516:AO090005001183
uniprot id: Q2UQM5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

510516:AO090005000630
gene id: 510516:AO090005000630
uniprot id: Q2URZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

510516:AO090102000366
gene id: 510516:AO090102000366
uniprot id: Q2UAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

510516:AO090011000424
gene id: 510516:AO090011000424
uniprot id: Q2U0I7
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090003000656
gene id: 510516:AO090003000656
uniprot id: Q2UKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3 and histone H4.
messages: Nucleus

510516:AO090001000295
gene id: 510516:AO090001000295
uniprot id: Q2UNN3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

510516:AO090011000367
gene id: 510516:AO090011000367
uniprot id: Q2U0N4
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

510516:AO090003001019
gene id: 510516:AO090003001019
uniprot id: Q2UJY9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

510516:AO090026000102
gene id: 510516:AO090026000102
uniprot id: Q2UFR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

510516:AO090011000576
gene id: 510516:AO090011000576
uniprot id: Q2U059
names: Function
names: Similarity
names: Subunit
messages: Belongs to the mannitol dehydrogenase family.
messages: Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
messages: Monomer.

510516:AO090102000102
gene id: 510516:AO090102000102
uniprot id: Q2UB55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

510516:AO090023000076
gene id: 510516:AO090023000076
uniprot id: Q2UIF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

510516:AO090701000675
gene id: 510516:AO090701000675
uniprot id: Q2U7W5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090026000562
gene id: 510516:AO090026000562
uniprot id: Q2UEM3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090120000226
gene id: 510516:AO090120000226
uniprot id: Q2U6I2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

510516:AO090701000758
gene id: 510516:AO090701000758
uniprot id: Q2U7P3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

510516:AO090038000426
gene id: 510516:AO090038000426
uniprot id: Q2U2K0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090020000339
gene id: 510516:AO090020000339
uniprot id: Q2U4H7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

510516:AO090038000053
gene id: 510516:AO090038000053
uniprot id: Q2U3G0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090206000067
gene id: 510516:AO090206000067
uniprot id: Q2PIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.

510516:AO090012001005
gene id: 510516:AO090012001005
uniprot id: Q2UBG9
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

510516:AO090003000737
gene id: 510516:AO090003000737
uniprot id: Q2UKN4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000175
gene id: 510516:AO090001000175
uniprot id: Q2UNZ1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000058
gene id: 510516:AO090102000058
uniprot id: Q2UB96
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090012000858
gene id: 510516:AO090012000858
uniprot id: Q2UBU7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

510516:AO090003000791
gene id: 510516:AO090003000791
uniprot id: Q2UKI6
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

510516:AO090010000171
gene id: 510516:AO090010000171
uniprot id: Q2TXF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.
messages: Fatty acid synthase alpha subunit; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).
messages: Fatty acid synthase is composed of alpha and beta subunits.

510516:AO090005001272
gene id: 510516:AO090005001272
uniprot id: Q2UQF5
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

510516:AO090005000694
gene id: 510516:AO090005000694
uniprot id: Q2URT7
names: Subunit
messages: Homodimer.

510516:AO090010000543
gene id: 510516:AO090010000543
uniprot id: Q2TWI4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001315
gene id: 510516:AO090005001315
uniprot id: Q2UQB8
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

510516:AO090026000732
gene id: 510516:AO090026000732
uniprot id: Q2UE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090020000347
gene id: 510516:AO090020000347
uniprot id: Q2U4H0
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

510516:AO090009000536
gene id: 510516:AO090009000536
uniprot id: Q2UTY8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000719
gene id: 510516:AO090026000719
uniprot id: Q2UE88
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003000205
gene id: 510516:AO090003000205
uniprot id: Q2ULZ8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090005001458
gene id: 510516:AO090005001458
uniprot id: Q2UPY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

510516:AO090003001436
gene id: 510516:AO090003001436
uniprot id: Q2UIX6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000462
gene id: 510516:AO090120000462
uniprot id: Q2U5Y0
names: Similarity
messages: Belongs to the EME1/MMS4 family.

510516:AO090011000301
gene id: 510516:AO090011000301
uniprot id: Q2U0U5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003000954
gene id: 510516:AO090003000954
uniprot id: Q2UK47
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090012000537
gene id: 510516:AO090012000537
uniprot id: Q2UCL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

510516:AO090003000689
gene id: 510516:AO090003000689
uniprot id: Q2UKS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090012000135
gene id: 510516:AO090012000135
uniprot id: Q2UDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
messages: Secreted

510516:AO090102000114
gene id: 510516:AO090102000114
uniprot id: Q2UB45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

510516:AO090038000517
gene id: 510516:AO090038000517
uniprot id: Q2U2C0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

510516:AO090001000659
gene id: 510516:AO090001000659
uniprot id: Q2UMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

510516:AO090009000688
gene id: 510516:AO090009000688
uniprot id: Q2UTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.

510516:AO090023000899
gene id: 510516:AO090023000899
uniprot id: Q2UGB9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

510516:AO090102000168
gene id: 510516:AO090102000168
uniprot id: Q2UAZ8
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554). The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554). Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554). During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable). O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable). Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable). PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).
messages: Does not affecct the production of 2,4'-dihydroxy-3'-methoxypropiophenone or 4'-hydroxy-3'-methoxypropiophenone.
messages: Membrane

510516:AO090020000162
gene id: 510516:AO090020000162
uniprot id: Q2U4X6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090701000725
gene id: 510516:AO090701000725
uniprot id: Q2U7S1
names: Similarity
messages: Belongs to the PdxS/SNZ family.

510516:AO090103000401
gene id: 510516:AO090103000401
uniprot id: Q2TY41
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090005000840
gene id: 510516:AO090005000840
uniprot id: Q2URG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

510516:AO090012000561
gene id: 510516:AO090012000561
uniprot id: Q2UCJ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003000418
gene id: 510516:AO090003000418
uniprot id: Q2ULG7
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

510516:AO090011000929
gene id: 510516:AO090011000929
uniprot id: Q2TZA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuole membrane

510516:AO090003000539
gene id: 510516:AO090003000539
uniprot id: Q2UL59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

510516:AO090003001063
gene id: 510516:AO090003001063
uniprot id: Q2UJV0
names: Similarity
messages: Belongs to the TFP11/STIP family.

510516:AO090038000563
gene id: 510516:AO090038000563
uniprot id: Q2U284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

510516:AO090120000074
gene id: 510516:AO090120000074
uniprot id: Q2U6W1
names: Function
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

510516:AO090102000626
gene id: 510516:AO090102000626
uniprot id: Q2U9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090010000518
gene id: 510516:AO090010000518
uniprot id: Q2TWK8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090010000587
gene id: 510516:AO090010000587
uniprot id: Q2TWF1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090005000727
gene id: 510516:AO090005000727
uniprot id: Q2URQ7
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

510516:AO090012000974
gene id: 510516:AO090012000974
uniprot id: Q2UBJ4
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090012000402
gene id: 510516:AO090012000402
uniprot id: Q2UCY0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

510516:AO090003000369
gene id: 510516:AO090003000369
uniprot id: Q2ULL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the epsin family.
messages: Membrane

510516:AO090003001344
gene id: 510516:AO090003001344
uniprot id: Q2UJ61
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001650
gene id: 510516:AO090005001650
uniprot id: Q2UPG6
names: Function
names: Similarity
messages: Belongs to the exportin family.
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.

510516:AO090038000132
gene id: 510516:AO090038000132
uniprot id: Q2U394
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

510516:AO090003000939
gene id: 510516:AO090003000939
uniprot id: Q2UK62
names: Similarity
messages: Belongs to the VPS52 family.

510516:AO090005000455
gene id: 510516:AO090005000455
uniprot id: Q2USE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

510516:AO090026000163
gene id: 510516:AO090026000163
uniprot id: Q2UFL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090023000834
gene id: 510516:AO090023000834
uniprot id: Q2UGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

510516:AO090001000230
gene id: 510516:AO090001000230
uniprot id: Q2UNU3
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090138000058
gene id: 510516:AO090138000058
uniprot id: Q2U1X5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090102000565
gene id: 510516:AO090102000565
uniprot id: Q2UA32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

510516:AO090026000455
gene id: 510516:AO090026000455
uniprot id: Q2UEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Cell membrane
messages: Membrane

510516:AO090001000172
gene id: 510516:AO090001000172
uniprot id: Q2UNZ4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000284
gene id: 510516:AO090026000284
uniprot id: Q2UFA5
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

510516:AO090011000614
gene id: 510516:AO090011000614
uniprot id: Q2U026
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090010000756
gene id: 510516:AO090010000756
uniprot id: Q2TW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

510516:AO090023000520
gene id: 510516:AO090023000520
uniprot id: Q2UHA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

510516:AO090038000430
gene id: 510516:AO090038000430
uniprot id: Q2U2J6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

510516:AO090026000027
gene id: 510516:AO090026000027
uniprot id: Q2UFY8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003000574
gene id: 510516:AO090003000574
uniprot id: Q2UL26
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

510516:AO090011000165
gene id: 510516:AO090011000165
uniprot id: Q2U154
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000451
gene id: 510516:AO090005000451
uniprot id: Q2USF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

510516:AO090701000164
gene id: 510516:AO090701000164
uniprot id: Q2U957
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

510516:AO090001000713
gene id: 510516:AO090001000713
uniprot id: Q2UML2
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005001122
gene id: 510516:AO090005001122
uniprot id: Q2UQS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

510516:AO090012000420
gene id: 510516:AO090012000420
uniprot id: Q2UCW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090038000575
gene id: 510516:AO090038000575
uniprot id: Q2U273
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090020000280
gene id: 510516:AO090020000280
uniprot id: Q2U4M5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000499
gene id: 510516:AO090011000499
uniprot id: Q2U0C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

510516:AO090020000555
gene id: 510516:AO090020000555
uniprot id: Q2U3Z6
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090023000061
gene id: 510516:AO090023000061
uniprot id: Q2UIG8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000579
gene id: 510516:AO090102000579
uniprot id: Q2UA18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

510516:AO090010000054
gene id: 510516:AO090010000054
uniprot id: Q2TXQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090120000317
gene id: 510516:AO090120000317
uniprot id: Q2U6A6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000364
gene id: 510516:AO090701000364
uniprot id: Q2U8M9
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Homotetramer.

510516:AO090003000513
gene id: 510516:AO090003000513
uniprot id: Q2UL82
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

510516:AO090026000503
gene id: 510516:AO090026000503
uniprot id: Q2UES4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

510516:AO090012000216
gene id: 510516:AO090012000216
uniprot id: Q2UDD5
names: Similarity
messages: Belongs to the DCC1 family.

510516:AO090011000364
gene id: 510516:AO090011000364
uniprot id: Q2U0N6
names: Similarity
messages: Belongs to the polysaccharide monooxygenase AA13 family.

510516:AO090005000638
gene id: 510516:AO090005000638
uniprot id: Q2URY7
names: Similarity
messages: Belongs to the DapA family.

510516:AO090701000082
gene id: 510516:AO090701000082
uniprot id: Q2U9C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LOC1 family.
messages: Component of the 66S pre-ribosomal particle.
messages: Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
messages: nucleolus

510516:AO090020000020
gene id: 510516:AO090020000020
uniprot id: Q2U597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

510516:AO090005000883
gene id: 510516:AO090005000883
uniprot id: Q2URC5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

510516:AO090001000445
gene id: 510516:AO090001000445
uniprot id: Q2UNA2
names: Function
names: Induction
names: Similarity
messages: Functions as a fatty acid monooxygenase. Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain.
messages: In the N-terminal section; belongs to the cytochrome P450 family.
messages: Induced by nitrogen limitation.

510516:AO090166000103
gene id: 510516:AO090166000103
uniprot id: Q2U9L4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090023000054
gene id: 510516:AO090023000054
uniprot id: Q2UIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005000735
gene id: 510516:AO090005000735
uniprot id: Q2URQ0
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

510516:AO090020000071
gene id: 510516:AO090020000071
uniprot id: Q2U551
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

510516:AO090005000355
gene id: 510516:AO090005000355
uniprot id: Q2USN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

510516:AO090102000231
gene id: 510516:AO090102000231
uniprot id: Q2UAU5
names: Similarity
messages: Belongs to the IlvD/Edd family.

510516:AO090023000523
gene id: 510516:AO090023000523
uniprot id: Q2UHA4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090701000296
gene id: 510516:AO090701000296
uniprot id: Q2U8T8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090038000112
gene id: 510516:AO090038000112
uniprot id: Q2U3B1
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090011000791
gene id: 510516:AO090011000791
uniprot id: Q2TZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

510516:AO090012000486
gene id: 510516:AO090012000486
uniprot id: Q2UCQ9
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

510516:AO090701000597
gene id: 510516:AO090701000597
uniprot id: Q2U827
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090020000027
gene id: 510516:AO090020000027
uniprot id: Q2U591
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

510516:AO090005001464
gene id: 510516:AO090005001464
uniprot id: Q2UPY0
names: Similarity
messages: Belongs to the FAH family.

510516:AO090701000275
gene id: 510516:AO090701000275
uniprot id: Q2U8V8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090009000682
gene id: 510516:AO090009000682
uniprot id: Q2UTL6
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

510516:AO090012000249
gene id: 510516:AO090012000249
uniprot id: Q2UDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

510516:AO090011000835
gene id: 510516:AO090011000835
uniprot id: Q2TZI9
names: Similarity
messages: Belongs to the isochorismatase family.

510516:AO090001000016
gene id: 510516:AO090001000016
uniprot id: Q2UPD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

510516:AO090038000291
gene id: 510516:AO090038000291
uniprot id: Q2U2W6
names: Similarity
messages: Belongs to the SAS10 family.

510516:AO090009000030
gene id: 510516:AO090009000030
uniprot id: Q2UV63
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000595
gene id: 510516:AO090005000595
uniprot id: Q2US27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus

510516:AO090003001186
gene id: 510516:AO090003001186
uniprot id: Q2UJJ4
names: Disruption Phenotype
names: Function
names: Subcellular Location Annotation
messages: Leads to longer aerial hyphae and to decreased conidia production (PubMed:30790620). Decreases transcriptional levels of the central development pathway genes brlA, abaA, and wetA during conidiation (PubMed:30790620). Leads to increased expression of kojR and kojA and a subsequent 6-fold increase of kojic acid production (PubMed:30790620).
messages: Nucleus
messages: Transcription factor that regulates conidiation as well as kojic acid production, likely by negatively controlling kojR and kojA expression.

510516:AO090003000469
gene id: 510516:AO090003000469
uniprot id: Q2ULB9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090011000034
gene id: 510516:AO090011000034
uniprot id: Q2U1G9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000586
gene id: 510516:AO090026000586
uniprot id: Q2UEK1
names: Similarity
messages: Belongs to the PAL/histidase family.

510516:AO090005001224
gene id: 510516:AO090005001224
uniprot id: Q2UQJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

510516:AO090026000705
gene id: 510516:AO090026000705
uniprot id: Q2UE99
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

510516:AO090020000015
gene id: 510516:AO090020000015
uniprot id: Q2U5A0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.
messages: Secreted

510516:AO090012000721
gene id: 510516:AO090012000721
uniprot id: Q2UC65
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

510516:AO090701000017
gene id: 510516:AO090701000017
uniprot id: Q2U9I5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090701000110
gene id: 510516:AO090701000110
uniprot id: Q2U9A3
names: Similarity
messages: Belongs to the MIT1/WOR1 family.

510516:AO090011000235
gene id: 510516:AO090011000235
uniprot id: Q2U0Z5
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

510516:AO090005000379
gene id: 510516:AO090005000379
uniprot id: Q2USL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090020000404
gene id: 510516:AO090020000404
uniprot id: Q2U4C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pectinesterase family.
messages: Involved in maceration and soft-rotting of plant tissue.
messages: Secreted

510516:AO090005001176
gene id: 510516:AO090005001176
uniprot id: Q2UQN1
names: Similarity
messages: Belongs to the CCDC124 family.

510516:AO090005001234
gene id: 510516:AO090005001234
uniprot id: Q2UQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

510516:AO090138000046
gene id: 510516:AO090138000046
uniprot id: Q2U1Y6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

510516:AO090005001362
gene id: 510516:AO090005001362
uniprot id: Q2UQ76
names: Similarity
messages: Belongs to the TMA16 family.

510516:AO090011000868
gene id: 510516:AO090011000868
uniprot id: O13416
names: Similarity
messages: Belongs to the OMP decarboxylase family.

510516:AO090005001614
gene id: 510516:AO090005001614
uniprot id: Q2UPJ7
names: Similarity
messages: Belongs to the PITHD1 family.

510516:AO090005001363
gene id: 510516:AO090005001363
uniprot id: Q2UQ75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

510516:AO090001000615
gene id: 510516:AO090001000615
uniprot id: Q2UMV0
names: Similarity
messages: Belongs to the AATF family.

510516:AO090020000695
gene id: 510516:AO090020000695
uniprot id: Q2U3M7
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090701000639
gene id: 510516:AO090701000639
uniprot id: Q2U7Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

510516:AO090003001316
gene id: 510516:AO090003001316
uniprot id: Q2UJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

510516:AO090011000948
gene id: 510516:AO090011000948
uniprot id: Q2TZ93
names: Similarity
messages: Belongs to the sorting nexin family.

510516:AO090038000412
gene id: 510516:AO090038000412
uniprot id: Q2U2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

510516:AO090701000892
gene id: 510516:AO090701000892
uniprot id: Q2U7C6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090005001057
gene id: 510516:AO090005001057
uniprot id: Q2UQY0
names: Function
names: Similarity
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.

510516:AO090124000010
gene id: 510516:AO090124000010
uniprot id: Q2U7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: cytoskeleton

510516:AO090103000412
gene id: 510516:AO090103000412
uniprot id: Q2TY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

510516:AO090011000812
gene id: 510516:AO090011000812
uniprot id: Q2TZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm

510516:AO090138000120
gene id: 510516:AO090138000120
uniprot id: Q2U1S0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090026000520
gene id: 510516:AO090026000520
uniprot id: Q2UEQ8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

510516:AO090005000530
gene id: 510516:AO090005000530
uniprot id: Q2US84
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090011000557
gene id: 510516:AO090011000557
uniprot id: Q2U075
names: Similarity
messages: Belongs to the arginase family.

510516:AO090005000442
gene id: 510516:AO090005000442
uniprot id: Q2USF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

510516:AO090001000359
gene id: 510516:AO090001000359
uniprot id: Q2UNH9
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

510516:AO090023000401
gene id: 510516:AO090023000401
uniprot id: Q2UHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
messages: Secreted

510516:AO090701000801
gene id: 510516:AO090701000801
uniprot id: Q2U7K6
names: Similarity
messages: Belongs to the GILT family.

510516:AO090012000119
gene id: 510516:AO090012000119
uniprot id: Q2UDM2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

510516:AO090009000431
gene id: 510516:AO090009000431
uniprot id: Q2UU71
names: Similarity
messages: Belongs to the VPS25 family.

510516:AO090003000442
gene id: 510516:AO090003000442
uniprot id: Q2ULE4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090103000274
gene id: 510516:AO090103000274
uniprot id: Q2TYF1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000769
gene id: 510516:AO090005000769
uniprot id: Q2URM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090102000513
gene id: 510516:AO090102000513
uniprot id: Q2UA74
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090026000704
gene id: 510516:AO090026000704
uniprot id: Q2UEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NUF2 family.
messages: Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.
messages: Nucleus
messages: kinetochore

510516:AO090012000199
gene id: 510516:AO090012000199
uniprot id: Q2UDE9
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

510516:AO090005000986
gene id: 510516:AO090005000986
uniprot id: Q2UR38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Secreted
messages: Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.

510516:AO090120000503
gene id: 510516:AO090120000503
uniprot id: Q2U5U9
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090009000505
gene id: 510516:AO090009000505
uniprot id: Q2UU14
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090003000923
gene id: 510516:AO090003000923
uniprot id: Q2UK76
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

510516:AO090011000732
gene id: 510516:AO090011000732
uniprot id: Q2TZT2
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

510516:AO090003000254
gene id: 510516:AO090003000254
uniprot id: Q2ULV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090011000824
gene id: 510516:AO090011000824
uniprot id: Q2TZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Nucleus

510516:AO090012000995
gene id: 510516:AO090012000995
uniprot id: Q2UBH7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

510516:AO090020000507
gene id: 510516:AO090020000507
uniprot id: Q2U437
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000624
gene id: 510516:AO090102000624
uniprot id: Q2U9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
messages: Nucleus

510516:AO090012000838
gene id: 510516:AO090012000838
uniprot id: Q2UBW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: The C-terminal short (CTS) helix is essential for catalytic activity. It may be accommodated as a transmembrane helix in the thinned membrane environment of the complex, similarly to the signal peptide in the complex substrates.

510516:AO090003001022
gene id: 510516:AO090003001022
uniprot id: Q2UJY6
names: Similarity
messages: Belongs to the FPG family.

510516:AO090005000159
gene id: 510516:AO090005000159
uniprot id: Q2UT48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

510516:AO090138000005
gene id: 510516:AO090138000005
uniprot id: Q2U219
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090701000872
gene id: 510516:AO090701000872
uniprot id: Q2U7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Membrane

510516:AO090023000840
gene id: 510516:AO090023000840
uniprot id: Q2UGH4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000751
gene id: 510516:AO090026000751
uniprot id: Q2UE60
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

510516:AO090012000847
gene id: 510516:AO090012000847
uniprot id: Q2UBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

510516:AO090026000228
gene id: 510516:AO090026000228
uniprot id: Q2UFF5
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

510516:AO090012000948
gene id: 510516:AO090012000948
uniprot id: Q2UBL6
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

510516:AO090023000259
gene id: 510516:AO090023000259
uniprot id: Q2UHY5
names: Similarity
messages: Belongs to the ERT1/acuK family.

510516:AO090003000524
gene id: 510516:AO090003000524
uniprot id: Q2UL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Secreted

510516:AO090023000801
gene id: 510516:AO090023000801
uniprot id: Q2UGL1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

510516:AO090701000189
gene id: 510516:AO090701000189
uniprot id: Q2U935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Nucleus

510516:AO090009000109
gene id: 510516:AO090009000109
uniprot id: Q2UUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

510516:AO090005001277
gene id: 510516:AO090005001277
uniprot id: Q2UQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

510516:AO090038000417
gene id: 510516:AO090038000417
uniprot id: Q2U2K8
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

510516:AO090010000340
gene id: 510516:AO090010000340
uniprot id: Q2TX03
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090011000883
gene id: 510516:AO090011000883
uniprot id: Q2TZE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

510516:AO090124000009
gene id: 510516:AO090124000009
uniprot id: Q2U7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).
messages: Secreted

510516:AO090020000430
gene id: 510516:AO090020000430
uniprot id: Q2U497
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

510516:AO090103000346
gene id: 510516:AO090103000346
uniprot id: Q2TY88
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000704
gene id: 510516:AO090701000704
uniprot id: Q2U7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Membrane

510516:AO090020000527
gene id: 510516:AO090020000527
uniprot id: Q2U420
names: Similarity
messages: Belongs to the tryptophan dimethylallyltransferase family.

510516:AO090023000231
gene id: 510516:AO090023000231
uniprot id: Q2UI12
names: Similarity
messages: Belongs to the Tango6 family.

510516:AO090005001133
gene id: 510516:AO090005001133
uniprot id: Q2UQR6
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090003000277
gene id: 510516:AO090003000277
uniprot id: Q2ULT4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000909
gene id: 510516:AO090011000909
uniprot id: Q2TZC7
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090010000761
gene id: 510516:AO090010000761
uniprot id: Q2TVZ5
names: Similarity
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.

510516:AO090003001228
gene id: 510516:AO090003001228
uniprot id: Q2UJG4
names: Similarity
messages: Belongs to the syntaxin family.

510516:AO090701000063
gene id: 510516:AO090701000063
uniprot id: Q2U9E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FES1 family.
messages: Cytoplasm
messages: Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity).

510516:AO090026000550
gene id: 510516:AO090026000550
uniprot id: Q2UEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Membrane

510516:AO090005001381
gene id: 510516:AO090005001381
uniprot id: Q2UQ59
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

510516:AO090701000462
gene id: 510516:AO090701000462
uniprot id: Q2U8E3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

510516:AO090005000757
gene id: 510516:AO090005000757
uniprot id: Q2URN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Membrane
messages: Mitochondrion

510516:AO090166000066
gene id: 510516:AO090166000066
uniprot id: Q2U9P8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000137
gene id: 510516:AO090701000137
uniprot id: Q2U980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

510516:AO090023000933
gene id: 510516:AO090023000933
uniprot id: Q2UG92
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

510516:AO090010000659
gene id: 510516:AO090010000659
uniprot id: Q2TW88
names: Similarity
messages: Belongs to the FAH family.

510516:AO090001000419
gene id: 510516:AO090001000419
uniprot id: Q2UNC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090026000297
gene id: 510516:AO090026000297
uniprot id: Q2UF93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090003000149
gene id: 510516:AO090003000149
uniprot id: Q2UM42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat creC family.
messages: Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).
messages: Interacts with creB.

510516:AO090012000169
gene id: 510516:AO090012000169
uniprot id: Q2UDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

510516:AO090003001552
gene id: 510516:AO090003001552
uniprot id: Q2UIM9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000425
gene id: 510516:AO090120000425
uniprot id: Q2U610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

510516:AO090701000158
gene id: 510516:AO090701000158
uniprot id: Q2U962
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

510516:AO090020000697
gene id: 510516:AO090020000697
uniprot id: Q2U3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 75 family.
messages: Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall. Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity.
messages: Secreted

510516:AO090001000471
gene id: 510516:AO090001000471
uniprot id: Q2UN80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

510516:AO090023000546
gene id: 510516:AO090023000546
uniprot id: Q2UH85
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090010000216
gene id: 510516:AO090010000216
uniprot id: Q2TXB0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

510516:AO090001000735
gene id: 510516:AO090001000735
uniprot id: Q2UMJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090005000347
gene id: 510516:AO090005000347
uniprot id: Q2USP5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090012000845
gene id: 510516:AO090012000845
uniprot id: Q2UBV6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090701000533
gene id: 510516:AO090701000533
uniprot id: Q2U884
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001119
gene id: 510516:AO090005001119
uniprot id: Q2UQS7
names: Similarity
messages: Belongs to the FAX family.

510516:AO090011000339
gene id: 510516:AO090011000339
uniprot id: Q2U0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

510516:AO090012000259
gene id: 510516:AO090012000259
uniprot id: Q2UDA0
names: Similarity
messages: Belongs to the hexokinase family.

510516:AO090120000343
gene id: 510516:AO090120000343
uniprot id: Q2U682
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

510516:AO090003000211
gene id: 510516:AO090003000211
uniprot id: Q2ULZ2
names: Similarity
messages: Belongs to the FAH family.

510516:AO090113000080
gene id: 510516:AO090113000080
uniprot id: Q2U5M9
names: Similarity
messages: Belongs to the p23/wos2 family.

510516:AO090001000617
gene id: 510516:AO090001000617
uniprot id: Q2UMU8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090120000170
gene id: 510516:AO090120000170
uniprot id: Q2U6N0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090012000254
gene id: 510516:AO090012000254
uniprot id: Q2UDA3
names: Similarity
messages: Belongs to the GILT family.

510516:AO090009000480
gene id: 510516:AO090009000480
uniprot id: Q2UU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

510516:AO090023000452
gene id: 510516:AO090023000452
uniprot id: Q2UHG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005000100
gene id: 510516:AO090005000100
uniprot id: Q2UTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Mitochondrion inner membrane

510516:AO090120000318
gene id: 510516:AO090120000318
uniprot id: Q2U6A5
names: Similarity
messages: Belongs to the EIF1AD family.

510516:AO090003001013
gene id: 510516:AO090003001013
uniprot id: Q2UJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

510516:AO090005000300
gene id: 510516:AO090005000300
uniprot id: Q2UST6
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

510516:AO090012000998
gene id: 510516:AO090012000998
uniprot id: Q2UBH4
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

510516:AO090012000901
gene id: 510516:AO090012000901
uniprot id: Q2UBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

510516:AO090020000596
gene id: 510516:AO090020000596
uniprot id: Q2U3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

510516:AO090206000030
gene id: 510516:AO090206000030
uniprot id: Q2PIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090005001632
gene id: 510516:AO090005001632
uniprot id: Q2UPI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
messages: trans-Golgi network membrane

510516:AO090012000203
gene id: 510516:AO090012000203
uniprot id: Q2UDE6
names: Similarity
messages: Belongs to the RNase PH family.

510516:AO090003000782
gene id: 510516:AO090003000782
uniprot id: Q2UKJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090001000385
gene id: 510516:AO090001000385
uniprot id: Q2UNF7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000615
gene id: 510516:AO090003000615
uniprot id: Q2UKY8
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

510516:AO090701000039
gene id: 510516:AO090701000039
uniprot id: Q2U9G5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001205
gene id: 510516:AO090003001205
uniprot id: Q2UJI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

510516:AO090020000639
gene id: 510516:AO090020000639
uniprot id: Q2U3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005000976
gene id: 510516:AO090005000976
uniprot id: Q2UR45
names: Similarity
messages: Belongs to the PRP18 family.

510516:AO090103000213
gene id: 510516:AO090103000213
uniprot id: Q2TYK1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

510516:AO090701000053
gene id: 510516:AO090701000053
uniprot id: Q2U9F2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

510516:AO090011000659
gene id: 510516:AO090011000659
uniprot id: Q9HGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPI family.
messages: Homodimer.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.
messages: cytosol

510516:AO090026000775
gene id: 510516:AO090026000775
uniprot id: Q2UE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090001000657
gene id: 510516:AO090001000657
uniprot id: Q2UMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Mitochondrion inner membrane

510516:AO090005000666
gene id: 510516:AO090005000666
uniprot id: Q2URW4
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090012000297
gene id: 510516:AO090012000297
uniprot id: Q2UD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

510516:AO090012000899
gene id: 510516:AO090012000899
uniprot id: Q2UBR3
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

510516:AO090206000079
gene id: 510516:AO090206000079
uniprot id: Q2PIS8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

510516:AO090103000025
gene id: 510516:AO090103000025
uniprot id: Q2TZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

510516:AO090005001317
gene id: 510516:AO090005001317
uniprot id: Q2UQB6
names: Similarity
messages: Belongs to the FMO family.

510516:AO090020000289
gene id: 510516:AO090020000289
uniprot id: Q2U4L7
names: Activity Regulation
names: Biotechnology
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activity is inhibited by about 80% in the presence of 18% sodium chloride.
messages: Belongs to the fungal glutaminase gtaA family.
messages: Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism. Catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine.
messages: In the fermentation of soy sauce, the traditional Japanese seasoning, glutaminase is one of the most important enzymes in flavor enhancement as it converts glutamine to glutamic acid.
messages: Secreted

510516:AO090038000193
gene id: 510516:AO090038000193
uniprot id: Q2U347
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090012000026
gene id: 510516:AO090012000026
uniprot id: Q2UDU4
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090026000626
gene id: 510516:AO090026000626
uniprot id: Q2UEG6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090038000167
gene id: 510516:AO090038000167
uniprot id: Q2U366
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090009000178
gene id: 510516:AO090009000178
uniprot id: Q2UUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 47 family.
messages: Cytoplasmic vesicle lumen
messages: Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
messages: Monomer.

510516:AO090120000142
gene id: 510516:AO090120000142
uniprot id: Q2U6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

510516:AO090005000560
gene id: 510516:AO090005000560
uniprot id: Q2US58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

510516:AO090010000230
gene id: 510516:AO090010000230
uniprot id: Q2TX97
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090701000349
gene id: 510516:AO090701000349
uniprot id: Q2U8P2
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

510516:AO090003001128
gene id: 510516:AO090003001128
uniprot id: Q2UJP6
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090701000263
gene id: 510516:AO090701000263
uniprot id: Q2U8W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

510516:AO090102000637
gene id: 510516:AO090102000637
uniprot id: Q2U9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090012000548
gene id: 510516:AO090012000548
uniprot id: Q2UCK6
names: Similarity
messages: Belongs to the actin family.

510516:AO090206000125
gene id: 510516:AO090206000125
uniprot id: Q2PIP1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

510516:AO090023000854
gene id: 510516:AO090023000854
uniprot id: Q2UGG1
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

510516:AO090120000449
gene id: 510516:AO090120000449
uniprot id: Q2U5Z0
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090701000360
gene id: 510516:AO090701000360
uniprot id: Q2U8N3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

510516:AO090005001209
gene id: 510516:AO090005001209
uniprot id: Q2UQK6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

510516:AO090003000592
gene id: 510516:AO090003000592
uniprot id: Q2UL09
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000354
gene id: 510516:AO090120000354
uniprot id: Q2U673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090038000061
gene id: 510516:AO090038000061
uniprot id: Q00234
names: Activity Regulation
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by acidifying treatment at pH 3.0.
messages: Belongs to the tyrosinase family.
messages: Binds 2 copper ions per subunit.
messages: Homotetramer.
messages: The N-terminus is blocked.
messages: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.

510516:AO090010000741
gene id: 510516:AO090010000741
uniprot id: Q2TW15
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090003001298
gene id: 510516:AO090003001298
uniprot id: Q2UJA4
names: Subcellular Location Annotation
messages: Secreted

510516:AO090001000529
gene id: 510516:AO090001000529
uniprot id: Q2UN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

510516:AO090011000052
gene id: 510516:AO090011000052
uniprot id: Q2U1F3
names: Activity Regulation
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28E subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Calcium, magnesium and manganese cations reduce peptidase activity to 20.3-51.3 percent. The metal ion chelating reagent EDTA almost completely inhibits activity. The protease inhibitor bacitracin and the aminopeptidase B inhibitor bestatin, as well as DTT and beta-mercaptoethanol act also as lap A inhibitorsD.
messages: Expressed at higher level at alkaline conditions. May be under the control of pacC, the transcription factor that regulates pH-conditional gene expression. Expression is very low under normal condition, salt condition and heat-stress condition.
messages: Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
messages: Monomer.
messages: Secreted

510516:AO090003000683
gene id: 510516:AO090003000683
uniprot id: Q2UKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

510516:AO090011000095
gene id: 510516:AO090011000095
uniprot id: Q2U1B7
names: Similarity
messages: Belongs to the CWC26 family.

510516:AO090012000110
gene id: 510516:AO090012000110
uniprot id: Q2UDM9
names: Similarity
names: Subunit
messages: Belongs to the peptidase M28 family.
messages: Monomer.

510516:AO090020000712
gene id: 510516:AO090020000712
uniprot id: Q2U3L1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

510516:AO090001000752
gene id: 510516:AO090001000752
uniprot id: Q2UMH5
names: Similarity
messages: Belongs to the peptidase C19 family.

510516:AO090308000003
gene id: 510516:AO090308000003
uniprot id: Q2UPG2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

510516:AO090023000570
gene id: 510516:AO090023000570
uniprot id: Q2UH62
names: Similarity
messages: Belongs to the GST superfamily.

510516:AO090102000558
gene id: 510516:AO090102000558
uniprot id: Q2UA38
names: Similarity
messages: Belongs to the NDK family.

510516:AO090012000592
gene id: 510516:AO090012000592
uniprot id: Q2UCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the END3 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

510516:AO090023000405
gene id: 510516:AO090023000405
uniprot id: Q2UHL1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000236
gene id: 510516:AO090020000236
uniprot id: Q2U4R2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090701000504
gene id: 510516:AO090701000504
uniprot id: Q2U8A9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000472
gene id: 510516:AO090701000472
uniprot id: Q2U8D3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090206000019
gene id: 510516:AO090206000019
uniprot id: Q2PIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

510516:AO090701000338
gene id: 510516:AO090701000338
uniprot id: Q2U8Q2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001052
gene id: 510516:AO090003001052
uniprot id: Q2UJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

510516:AO090009000065
gene id: 510516:AO090009000065
uniprot id: Q2UV34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

510516:AO090012000012
gene id: 510516:AO090012000012
uniprot id: Q2UDV6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000279
gene id: 510516:AO090020000279
uniprot id: Q2U4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

510516:AO090120000042
gene id: 510516:AO090120000042
uniprot id: Q2U6Y6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090001000344
gene id: 510516:AO090001000344
uniprot id: Q2UNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase chs3 from the endoplasmic reticulum.
messages: Endoplasmic reticulum membrane
messages: Interacts with chs3.

510516:AO090026000537
gene id: 510516:AO090026000537
uniprot id: Q2UEP6
names: Similarity
messages: Belongs to the Rab GDI family.

510516:AO090005001305
gene id: 510516:AO090005001305
uniprot id: Q2UQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090038000415
gene id: 510516:AO090038000415
uniprot id: Q2U2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

510516:AO090005000297
gene id: 510516:AO090005000297
uniprot id: Q2UST9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

510516:AO090026000094
gene id: 510516:AO090026000094
uniprot id: Q2UFS5
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000578
gene id: 510516:AO090011000578
uniprot id: Q2U057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

510516:AO090003001423
gene id: 510516:AO090003001423
uniprot id: Q2UIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

510516:AO090005000085
gene id: 510516:AO090005000085
uniprot id: Q2UTB4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000354
gene id: 510516:AO090005000354
uniprot id: Q2USN8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000123
gene id: 510516:AO090023000123
uniprot id: Q2UIB4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090001000308
gene id: 510516:AO090001000308
uniprot id: Q2UNM2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000726
gene id: 510516:AO090001000726
uniprot id: Q2UMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

510516:AO090103000204
gene id: 510516:AO090103000204
uniprot id: Q2TYK9
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

510516:AO090038000031
gene id: 510516:AO090038000031
uniprot id: Q2U3H7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000530
gene id: 510516:AO090001000530
uniprot id: Q2UN26
names: Similarity
messages: Belongs to the CWC16 family.

510516:AO090103000002
gene id: 510516:AO090103000002
uniprot id: Q2TZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

510516:AO090026000229
gene id: 510516:AO090026000229
uniprot id: Q2UFF4
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

510516:AO090003000806
gene id: 510516:AO090003000806
uniprot id: Q2UKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

510516:AO090009000195
gene id: 510516:AO090009000195
uniprot id: Q2UUS6
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

510516:AO090005000545
gene id: 510516:AO090005000545
uniprot id: Q2US72
names: Function
names: Similarity
messages: Belongs to the choline monooxygenase family.
messages: Catalyzes the first step of the osmoprotectant glycine betaine synthesis.

510516:AO090005000904
gene id: 510516:AO090005000904
uniprot id: Q2URA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090010000750
gene id: 510516:AO090010000750
uniprot id: Q2TW06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090009000600
gene id: 510516:AO090009000600
uniprot id: Q2UTT5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

510516:AO090102000154
gene id: 510516:AO090102000154
uniprot id: Q2UB12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

510516:AO090138000062
gene id: 510516:AO090138000062
uniprot id: Q2U1X1
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

510516:AO090026000815
gene id: 510516:AO090026000815
uniprot id: Q2UE00
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

510516:AO090020000032
gene id: 510516:AO090020000032
uniprot id: Q2U586
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

510516:AO090009000426
gene id: 510516:AO090009000426
uniprot id: Q2UU76
names: Similarity
messages: Belongs to the RNR ribonuclease family.

510516:AO090026000264
gene id: 510516:AO090026000264
uniprot id: Q2UFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

510516:AO090001000561
gene id: 510516:AO090001000561
uniprot id: Q2UMZ5
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

510516:AO090003000003
gene id: 510516:AO090003000003
uniprot id: Q2UMH2
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

510516:AO090038000249
gene id: 510516:AO090038000249
uniprot id: Q2U302
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

510516:AO090138000113
gene id: 510516:AO090138000113
uniprot id: Q2U1S7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090023000335
gene id: 510516:AO090023000335
uniprot id: Q2UHS1
names: Similarity
messages: Belongs to the pirin family.

510516:AO090001000111
gene id: 510516:AO090001000111
uniprot id: P87037
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.
messages: Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
messages: Secreted

510516:AO090009000174
gene id: 510516:AO090009000174
uniprot id: Q2UUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

510516:AO090113000122
gene id: 510516:AO090113000122
uniprot id: Q2U5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

510516:AO090701000381
gene id: 510516:AO090701000381
uniprot id: Q2U8L5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090020000619
gene id: 510516:AO090020000619
uniprot id: Q2U3U1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

510516:AO090011000821
gene id: 510516:AO090011000821
uniprot id: Q2TZK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
messages: Lacks the conserved Glu residue in position 482 essential for carbopeptidase activity. The mature form lacks catalytic activity towards synthetic peptide substrates.
messages: Secreted
messages: Vacuole

510516:AO090026000105
gene id: 510516:AO090026000105
uniprot id: Q2UFR5
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090023000763
gene id: 510516:AO090023000763
uniprot id: Q2UGP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

510516:AO090102000502
gene id: 510516:AO090102000502
uniprot id: Q2UA84
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

510516:AO090023000858
gene id: 510516:AO090023000858
uniprot id: Q2UGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
messages: Nucleus

510516:AO090103000022
gene id: 510516:AO090103000022
uniprot id: Q2TZ14
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090003001549
gene id: 510516:AO090003001549
uniprot id: Q2UIN2
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

510516:AO090003000993
gene id: 510516:AO090003000993
uniprot id: Q2UK13
names: Similarity
messages: Belongs to the cyclin family.

510516:AO090038000262
gene id: 510516:AO090038000262
uniprot id: Q2U2Z1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

510516:AO090102000650
gene id: 510516:AO090102000650
uniprot id: Q2U9V6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090003001546
gene id: 510516:AO090003001546
uniprot id: Q2UIN5
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

510516:AO090124000084
gene id: 510516:AO090124000084
uniprot id: Q2U733
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

510516:AO090012000147
gene id: 510516:AO090012000147
uniprot id: Q2UDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
messages: Secreted

510516:AO090011000067
gene id: 510516:AO090011000067
uniprot id: Q2U1E0
names: Similarity
messages: Belongs to the CutC family.

510516:AO090003001020
gene id: 510516:AO090003001020
uniprot id: Q2UJY8
names: Function
names: Similarity
messages: Belongs to the NARF family.
messages: Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).

510516:AO090010000345
gene id: 510516:AO090010000345
uniprot id: Q2TWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090102000573
gene id: 510516:AO090102000573
uniprot id: Q2UA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

510516:AO090103000384
gene id: 510516:AO090103000384
uniprot id: Q2TY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Cell membrane
messages: Membrane
messages: cell wall

510516:AO090005000217
gene id: 510516:AO090005000217
uniprot id: Q2UT06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
messages: Secreted

510516:AO090038000321
gene id: 510516:AO090038000321
uniprot id: Q2U2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090001000653
gene id: 510516:AO090001000653
uniprot id: Q2UMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

510516:AO090003000754
gene id: 510516:AO090003000754
uniprot id: Q2UKM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

510516:AO090103000021
gene id: 510516:AO090103000021
uniprot id: Q2TZ15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090010000315
gene id: 510516:AO090010000315
uniprot id: Q2TX25
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090001000640
gene id: 510516:AO090001000640
uniprot id: Q2UMS6
names: Similarity
messages: Belongs to the PrpF family.

510516:AO090010000764
gene id: 510516:AO090010000764
uniprot id: Q2TVZ2
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

510516:AO090023000467
gene id: 510516:AO090023000467
uniprot id: Q2UHF6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090701000752
gene id: 510516:AO090701000752
uniprot id: Q2U7P9
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090003001415
gene id: 510516:AO090003001415
uniprot id: Q2UIZ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000535
gene id: 510516:AO090011000535
uniprot id: Q2U094
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

510516:AO090010000075
gene id: 510516:AO090010000075
uniprot id: Q2TXN5
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090012000544
gene id: 510516:AO090012000544
uniprot id: Q2UCL0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090103000206
gene id: 510516:AO090103000206
uniprot id: Q2TYK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000063
gene id: 510516:AO090011000063
uniprot id: Q2U1E4
names: Subunit
messages: Homotetramer.

510516:AO090012000403
gene id: 510516:AO090012000403
uniprot id: Q2UCX9
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

510516:AO090003000054
gene id: 510516:AO090003000054
uniprot id: Q2UMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090102000064
gene id: 510516:AO090102000064
uniprot id: Q2UB90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090010000223
gene id: 510516:AO090010000223
uniprot id: Q2TXA3
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

510516:AO090026000295
gene id: 510516:AO090026000295
uniprot id: Q2UF95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.
messages: Nucleus
messages: kinetochore
messages: spindle pole body

510516:AO090023000307
gene id: 510516:AO090023000307
uniprot id: Q2UHU5
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090012000909
gene id: 510516:AO090012000909
uniprot id: Q2UBQ5
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

510516:AO090020000064
gene id: 510516:AO090020000064
uniprot id: Q2U557
names: Similarity
messages: Belongs to the APC1 family.

510516:AO090003000270
gene id: 510516:AO090003000270
uniprot id: Q2ULU0
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090701000013
gene id: 510516:AO090701000013
uniprot id: Q2U9I9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

510516:AO090003001365
gene id: 510516:AO090003001365
uniprot id: Q2UJ42
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000195
gene id: 510516:AO090010000195
uniprot id: Q2TXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090011000352
gene id: 510516:AO090011000352
uniprot id: Q2U0P8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090113000014
gene id: 510516:AO090113000014
uniprot id: Q2U5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
messages: Vacuole membrane

510516:AO090120000291
gene id: 510516:AO090120000291
uniprot id: Q2U6C8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

510516:AO090120000455
gene id: 510516:AO090120000455
uniprot id: Q2U5Y6
names: Similarity
messages: Belongs to the arginase family.

510516:AO090103000479
gene id: 510516:AO090103000479
uniprot id: Q2TXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

510516:AO090012000204
gene id: 510516:AO090012000204
uniprot id: Q2UDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane

510516:AO090001000221
gene id: 510516:AO090001000221
uniprot id: Q2UNV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090023000257
gene id: 510516:AO090023000257
uniprot id: Q2UHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

510516:AO090038000543
gene id: 510516:AO090038000543
uniprot id: Q2U2A1
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090023000758
gene id: 510516:AO090023000758
uniprot id: Q2UGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

510516:AO090103000109
gene id: 510516:AO090103000109
uniprot id: Q2TYU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

510516:AO090005000308
gene id: 510516:AO090005000308
uniprot id: Q2USS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090120000131
gene id: 510516:AO090120000131
uniprot id: Q2U6R0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

510516:AO090023000555
gene id: 510516:AO090023000555
uniprot id: Q2UH77
names: Similarity
messages: Belongs to the tpcK family.

510516:AO090003001312
gene id: 510516:AO090003001312
uniprot id: Q2UJ92
names: Similarity
messages: Belongs to the UPF0047 family.

510516:AO090005001357
gene id: 510516:AO090005001357
uniprot id: Q2UQ81
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

510516:AO090003000016
gene id: 510516:AO090003000016
uniprot id: Q2UMF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

510516:AO090023000771
gene id: 510516:AO090023000771
uniprot id: Q2UGP0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

510516:AO090003000559
gene id: 510516:AO090003000559
uniprot id: Q2UL40
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090102000032
gene id: 510516:AO090102000032
uniprot id: Q2UBB9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

510516:AO090701000763
gene id: 510516:AO090701000763
uniprot id: Q2U7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

510516:AO090701000410
gene id: 510516:AO090701000410
uniprot id: Q2U8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005001515
gene id: 510516:AO090005001515
uniprot id: Q2UPT7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
messages: Endoplasmic reticulum
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

510516:AO090026000252
gene id: 510516:AO090026000252
uniprot id: Q2UFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).
messages: Secreted

510516:AO090138000041
gene id: 510516:AO090138000041
uniprot id: Q2U1Z1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090103000010
gene id: 510516:AO090103000010
uniprot id: Q2TZ25
names: Similarity
messages: Belongs to the MIP18 family.

510516:AO090038000233
gene id: 510516:AO090038000233
uniprot id: Q2U315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090012001019
gene id: 510516:AO090012001019
uniprot id: Q2UBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

510516:AO090005001595
gene id: 510516:AO090005001595
uniprot id: Q2UPL5
names: Similarity
messages: Belongs to the PP2C family.

510516:AO090120000167
gene id: 510516:AO090120000167
uniprot id: Q2U6N3
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

510516:AO090023000821
gene id: 510516:AO090023000821
uniprot id: Q2UGJ2
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090020000215
gene id: 510516:AO090020000215
uniprot id: Q2U4T1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090103000367
gene id: 510516:AO090103000367
uniprot id: Q2TY71
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000728
gene id: 510516:AO090023000728
uniprot id: Q2UGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

510516:AO090012000805
gene id: 510516:AO090012000805
uniprot id: Q2UBZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
messages: Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
messages: Component of pre-60S ribosomal complexes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090003000931
gene id: 510516:AO090003000931
uniprot id: Q2UK69
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

510516:AO090020000159
gene id: 510516:AO090020000159
uniprot id: Q2U4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
messages: In the C-terminal section; belongs to the phytoene/squalene synthase family.
messages: In the N-terminal section; belongs to the lycopene beta-cyclase family.
messages: Membrane

510516:AO090012000171
gene id: 510516:AO090012000171
uniprot id: Q2UDH4
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

510516:AO090005000804
gene id: 510516:AO090005000804
uniprot id: Q2URJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

510516:AO090001000669
gene id: 510516:AO090001000669
uniprot id: Q2UMQ0
names: Similarity
messages: Belongs to the HIT family.

510516:AO090701000476
gene id: 510516:AO090701000476
uniprot id: Q2U8D0
names: Similarity
messages: Belongs to the CIA30 family.

510516:AO090026000552
gene id: 510516:AO090026000552
uniprot id: Q2UEN3
names: Similarity
messages: Belongs to the PAF1 family.

510516:AO090701000206
gene id: 510516:AO090701000206
uniprot id: Q2U920
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090005000209
gene id: 510516:AO090005000209
uniprot id: Q2UT13
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090120000104
gene id: 510516:AO090120000104
uniprot id: Q2U6T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus

510516:AO090023000964
gene id: 510516:AO090023000964
uniprot id: Q2UG62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

510516:AO090701000132
gene id: 510516:AO090701000132
uniprot id: Q2U985
names: Similarity
messages: Belongs to the HEATR5 family.

510516:AO090009000136
gene id: 510516:AO090009000136
uniprot id: Q2UUX3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

510516:AO090003000012
gene id: 510516:AO090003000012
uniprot id: Q2UMG3
names: Function
names: Similarity
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.

510516:AO090012000794
gene id: 510516:AO090012000794
uniprot id: Q2UC06
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

510516:AO090005001117
gene id: 510516:AO090005001117
uniprot id: Q2UQS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090005000681
gene id: 510516:AO090005000681
uniprot id: Q2URV0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090701000887
gene id: 510516:AO090701000887
uniprot id: Q2U7D0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

510516:AO090102000274
gene id: 510516:AO090102000274
uniprot id: Q2UAR5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090001000557
gene id: 510516:AO090001000557
uniprot id: Q2UMZ9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

510516:AO090026000714
gene id: 510516:AO090026000714
uniprot id: Q2UE92
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

510516:AO090038000274
gene id: 510516:AO090038000274
uniprot id: Q2U2Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

510516:AO090120000256
gene id: 510516:AO090120000256
uniprot id: Q2U6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

510516:AO090120000008
gene id: 510516:AO090120000008
uniprot id: Q2U717
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
messages: Vacuole

510516:AO090026000357
gene id: 510516:AO090026000357
uniprot id: Q2UF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cerato-platanin family.
messages: Secreted

510516:AO090009000270
gene id: 510516:AO090009000270
uniprot id: Q2UUL3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000499
gene id: 510516:AO090001000499
uniprot id: Q2UN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pym family.
messages: Cytoplasm

510516:AO090010000579
gene id: 510516:AO090010000579
uniprot id: Q2TWF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090166000075
gene id: 510516:AO090166000075
uniprot id: Q2U9N9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Secreted

510516:AO090001000390
gene id: 510516:AO090001000390
uniprot id: Q2UNF3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090206000056
gene id: 510516:AO090206000056
uniprot id: Q2PIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

510516:AO090120000294
gene id: 510516:AO090120000294
uniprot id: Q2U6C6
names: Similarity
messages: Belongs to the HMBS family.

510516:AO090010000463
gene id: 510516:AO090010000463
uniprot id: Q2TWQ7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

510516:AO090010000424
gene id: 510516:AO090010000424
uniprot id: Q2TWT8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090005001332
gene id: 510516:AO090005001332
uniprot id: Q2UQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

510516:AO090038000058
gene id: 510516:AO090038000058
uniprot id: Q2U3F7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090010000314
gene id: 510516:AO090010000314
uniprot id: Q2TX26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090012000835
gene id: 510516:AO090012000835
uniprot id: Q2UBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

510516:AO090020000426
gene id: 510516:AO090020000426
uniprot id: Q2U4A1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

510516:AO090005000970
gene id: 510516:AO090005000970
uniprot id: Q2UR50
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090010000534
gene id: 510516:AO090010000534
uniprot id: Q2TWJ3
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090113000061
gene id: 510516:AO090113000061
uniprot id: Q2U5P3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000255
gene id: 510516:AO090120000255
uniprot id: Q2U6F7
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

510516:AO090003000707
gene id: 510516:AO090003000707
uniprot id: Q2UKR2
names: Similarity
messages: Belongs to the MNN1/MNT family.

510516:AO090120000129
gene id: 510516:AO090120000129
uniprot id: Q2U6R2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090103000446
gene id: 510516:AO090103000446
uniprot id: Q2TXZ9
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

510516:AO090003000575
gene id: 510516:AO090003000575
uniprot id: Q2UL25
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000232
gene id: 510516:AO090001000232
uniprot id: Q2UNU1
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

510516:AO090120000364
gene id: 510516:AO090120000364
uniprot id: Q2U664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family. CAF17 subfamily.
messages: Mitochondrion

510516:AO090103000012
gene id: 510516:AO090103000012
uniprot id: Q2TZ23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090011000290
gene id: 510516:AO090011000290
uniprot id: Q2U0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLT11 family.
messages: Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.
messages: Nucleus

510516:AO090003001390
gene id: 510516:AO090003001390
uniprot id: Q9HGZ1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

510516:AO090026000542
gene id: 510516:AO090026000542
uniprot id: Q2UEP2
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

510516:AO090005000739
gene id: 510516:AO090005000739
uniprot id: Q2URP6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

510516:AO090012000157
gene id: 510516:AO090012000157
uniprot id: Q2UDI8
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

510516:AO090124000088
gene id: 510516:AO090124000088
uniprot id: Q2U729
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

510516:AO090120000112
gene id: 510516:AO090120000112
uniprot id: Q2U6S7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

510516:AO090026000672
gene id: 510516:AO090026000672
uniprot id: Q2UEC7
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

510516:AO090026000526
gene id: 510516:AO090026000526
uniprot id: Q2UEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090010000622
gene id: 510516:AO090010000622
uniprot id: Q2TWC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

510516:AO090005000228
gene id: 510516:AO090005000228
uniprot id: Q2USZ6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000230
gene id: 510516:AO090011000230
uniprot id: Q2U100
names: Function
names: Similarity
names: Subunit
messages: Belongs to the mannitol dehydrogenase family.
messages: Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
messages: Monomer.

510516:AO090009000481
gene id: 510516:AO090009000481
uniprot id: Q2UU30
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

510516:AO090701000087
gene id: 510516:AO090701000087
uniprot id: Q2U9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
messages: nucleolus

510516:AO090020000217
gene id: 510516:AO090020000217
uniprot id: Q2U4S9
names: Similarity
messages: Belongs to the glutamine synthetase family.

510516:AO090011000441
gene id: 510516:AO090011000441
uniprot id: Q2U0H2
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

510516:AO090026000547
gene id: 510516:AO090026000547
uniprot id: Q2UEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

510516:AO090009000264
gene id: 510516:AO090009000264
uniprot id: Q2UUL9
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

510516:AO090005001572
gene id: 510516:AO090005001572
uniprot id: Q2UPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

510516:AO090120000396
gene id: 510516:AO090120000396
uniprot id: Q2U637
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

510516:AO090026000785
gene id: 510516:AO090026000785
uniprot id: Q2UE26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090003000609
gene id: 510516:AO090003000609
uniprot id: Q2UKZ4
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

510516:AO090120000135
gene id: 510516:AO090120000135
uniprot id: Q2U6Q7
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

510516:AO090005001078
gene id: 510516:AO090005001078
uniprot id: Q2UQW1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090001000594
gene id: 510516:AO090001000594
uniprot id: Q2UMW5
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

510516:AO090005000575
gene id: 510516:AO090005000575
uniprot id: Q2US46
names: Similarity
messages: Belongs to the OPA3 family.

510516:AO090020000690
gene id: 510516:AO090020000690
uniprot id: Q2U3N2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

510516:AO090120000257
gene id: 510516:AO090120000257
uniprot id: Q2U6F5
names: Similarity
messages: Belongs to the 14-3-3 family.

510516:AO090012001004
gene id: 510516:AO090012001004
uniprot id: Q2UBH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

510516:AO090120000157
gene id: 510516:AO090120000157
uniprot id: Q2U6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

510516:AO090005000842
gene id: 510516:AO090005000842
uniprot id: Q2URG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

510516:AO090102000642
gene id: 510516:AO090102000642
uniprot id: Q2U9W2
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

510516:AO090005000896
gene id: 510516:AO090005000896
uniprot id: Q2URB3
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090023000599
gene id: 510516:AO090023000599
uniprot id: Q2UH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

510516:AO090001000664
gene id: 510516:AO090001000664
uniprot id: Q2UMQ5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation at Lys-318 is required for proper function.
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z (By similarity). Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity). The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (By similarity). Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins (By similarity). In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (By similarity).
messages: Chromosome
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus
messages: The ESA1-RPD3 motif is common to ESA1 and RPD3 and is required for ESA1 histone acetyl-transferase (HAT) activity and RPD3 histone deacetylase (HDAC) activity.

510516:AO090103000320
gene id: 510516:AO090103000320
uniprot id: Q2TYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

510516:AO090005001072
gene id: 510516:AO090005001072
uniprot id: Q2UQW7
names: Similarity
messages: Belongs to the NOC2 family.

510516:AO090011000534
gene id: 510516:AO090011000534
uniprot id: Q2U095
names: Similarity
messages: Belongs to the MGR2 family.

510516:AO090026000741
gene id: 510516:AO090026000741
uniprot id: Q2UE69
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090102000056
gene id: 510516:AO090102000056
uniprot id: Q2UB98
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000714
gene id: 510516:AO090023000714
uniprot id: Q2UGU0
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

510516:AO090011000785
gene id: 510516:AO090011000785
uniprot id: Q2TZN5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005000494
gene id: 510516:AO090005000494
uniprot id: Q2USB5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

510516:AO090005001582
gene id: 510516:AO090005001582
uniprot id: Q2UPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090120000319
gene id: 510516:AO090120000319
uniprot id: Q2U6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG3 family.
messages: Endoplasmic reticulum membrane

510516:AO090701000241
gene id: 510516:AO090701000241
uniprot id: Q2U8Y8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001238
gene id: 510516:AO090003001238
uniprot id: Q2UJF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of mmm1, mdm10, mdm12 and mdm34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

510516:AO090003000133
gene id: 510516:AO090003000133
uniprot id: Q2UM55
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090012000503
gene id: 510516:AO090012000503
uniprot id: Q2UCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Nucleus
messages: Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity).

510516:AO090009000565
gene id: 510516:AO090009000565
uniprot id: Q2UTW4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000003
gene id: 510516:AO090701000003
uniprot id: Q2U9J8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090026000004
gene id: 510516:AO090026000004
uniprot id: Q2UG10
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000537
gene id: 510516:AO090011000537
uniprot id: Q2U092
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

510516:AO090026000495
gene id: 510516:AO090026000495
uniprot id: Q2UET1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

510516:AO090012000988
gene id: 510516:AO090012000988
uniprot id: Q2UBI1
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

510516:AO090010000598
gene id: 510516:AO090010000598
uniprot id: Q2TWE0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090102000602
gene id: 510516:AO090102000602
uniprot id: Q2U9Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

510516:AO090005000018
gene id: 510516:AO090005000018
uniprot id: Q2UTH3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000407
gene id: 510516:AO090003000407
uniprot id: Q2ULH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

510516:AO090020000194
gene id: 510516:AO090020000194
uniprot id: Q2U4V0
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

510516:AO090701000073
gene id: 510516:AO090701000073
uniprot id: Q2U9D3
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

510516:AO090102000039
gene id: 510516:AO090102000039
uniprot id: Q2UBB2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000268
gene id: 510516:AO090011000268
uniprot id: Q2U0X1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001100
gene id: 510516:AO090003001100
uniprot id: Q2UJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.

510516:AO090005000128
gene id: 510516:AO090005000128
uniprot id: Q2UT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

510516:AO090012000682
gene id: 510516:AO090012000682
uniprot id: Q2UC99
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090020000141
gene id: 510516:AO090020000141
uniprot id: Q2U4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090003000111
gene id: 510516:AO090003000111
uniprot id: Q2UM74
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090001000701
gene id: 510516:AO090001000701
uniprot id: Q2UMM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
messages: Zinc or magnesium.

510516:AO090003000263
gene id: 510516:AO090003000263
uniprot id: Q2ULU6
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit pan3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Positively regulated by the regulatory subunit pan3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with pan3.

510516:AO090038000551
gene id: 510516:AO090038000551
uniprot id: Q2U294
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090701000751
gene id: 510516:AO090701000751
uniprot id: Q2U7Q0
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090005001584
gene id: 510516:AO090005001584
uniprot id: Q2UPM5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000137
gene id: 510516:AO090012000137
uniprot id: Q2UDK5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090138000160
gene id: 510516:AO090138000160
uniprot id: Q2U1N5
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M36 family.
messages: Binds 1 zinc ion per subunit.
messages: Expression is controlled by the prtT transcription factor.
messages: Secreted
messages: Secreted metalloproteinase that allows assimilation of proteinaceous substrates.

510516:AO090038000466
gene id: 510516:AO090038000466
uniprot id: Q2U2G3
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090001000192
gene id: 510516:AO090001000192
uniprot id: Q2UNX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

510516:AO090005000853
gene id: 510516:AO090005000853
uniprot id: Q2URF2
names: Similarity
messages: Belongs to the UFD1 family.

510516:AO090012000830
gene id: 510516:AO090012000830
uniprot id: Q2UBX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090026000521
gene id: 510516:AO090026000521
uniprot id: Q2UEQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

510516:AO090103000168
gene id: 510516:AO090103000168
uniprot id: Q2TYP2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

510516:AO090012000252
gene id: 510516:AO090012000252
uniprot id: Q2UDA5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000744
gene id: 510516:AO090011000744
uniprot id: Q2TZS0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090103000151
gene id: 510516:AO090103000151
uniprot id: Q2TYQ6
names: Similarity
messages: Belongs to the HMBS family.

510516:AO090003000077
gene id: 510516:AO090003000077
uniprot id: Q2UMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090003000925
gene id: 510516:AO090003000925
uniprot id: Q2UK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

510516:AO090001000376
gene id: 510516:AO090001000376
uniprot id: Q2UNG5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

510516:AO090010000170
gene id: 510516:AO090010000170
uniprot id: Q2TXF1
names: Function
names: Similarity
messages: Belongs to the citrate synthase family.
messages: Citrate synthase-like protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).

510516:AO090023000628
gene id: 510516:AO090023000628
uniprot id: Q2UH16
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090038000396
gene id: 510516:AO090038000396
uniprot id: Q2U2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

510516:AO090026000491
gene id: 510516:AO090026000491
uniprot id: Q2UET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090701000692
gene id: 510516:AO090701000692
uniprot id: Q2U7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

510516:AO090038000349
gene id: 510516:AO090038000349
uniprot id: Q2U2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

510516:AO090120000460
gene id: 510516:AO090120000460
uniprot id: Q2U5Y2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

510516:AO090003001081
gene id: 510516:AO090003001081
uniprot id: Q2UJT6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000047
gene id: 510516:AO090023000047
uniprot id: Q2UII1
names: Similarity
messages: Belongs to the tannase family.

510516:AO090012000787
gene id: 510516:AO090012000787
uniprot id: Q2UC13
names: Similarity
messages: Belongs to the band 7/mec-2 family.

510516:AO090003001341
gene id: 510516:AO090003001341
uniprot id: Q2UJ64
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

510516:AO090138000091
gene id: 510516:AO090138000091
uniprot id: Q2U1U6
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

510516:AO090026000023
gene id: 510516:AO090026000023
uniprot id: Q2UFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anthrone oxygenase family.
messages: Membrane

510516:AO090701000753
gene id: 510516:AO090701000753
uniprot id: Q2U7P8
names: Similarity
messages: Belongs to the alpha-actinin family.

510516:AO090009000485
gene id: 510516:AO090009000485
uniprot id: Q2UU26
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

510516:AO090038000621
gene id: 510516:AO090038000621
uniprot id: Q2U233
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

510516:AO090038000090
gene id: 510516:AO090038000090
uniprot id: Q2U3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005001601
gene id: 510516:AO090005001601
uniprot id: Q2UPK9
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

510516:AO090005001261
gene id: 510516:AO090005001261
uniprot id: Q2UQG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.
messages: Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).
messages: Nucleus

510516:AO090001000337
gene id: 510516:AO090001000337
uniprot id: Q2UNJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

510516:AO090005001406
gene id: 510516:AO090005001406
uniprot id: Q2UQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090003000295
gene id: 510516:AO090003000295
uniprot id: Q2ULR9
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

510516:AO090120000101
gene id: 510516:AO090120000101
uniprot id: Q2U6T8
names: Similarity
messages: Belongs to the RNase PH family.

510516:AO090113000041
gene id: 510516:AO090113000041
uniprot id: Q2U5R2
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090020000429
gene id: 510516:AO090020000429
uniprot id: Q2U498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

510516:AO090023000450
gene id: 510516:AO090023000450
uniprot id: Q2UHH0
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090701000424
gene id: 510516:AO090701000424
uniprot id: Q2U8I0
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

510516:AO090005001021
gene id: 510516:AO090005001021
uniprot id: Q2UR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

510516:AO090103000444
gene id: 510516:AO090103000444
uniprot id: Q2TY01
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

510516:AO090011000167
gene id: 510516:AO090011000167
uniprot id: Q2U152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

510516:AO090010000390
gene id: 510516:AO090010000390
uniprot id: Q2TWW2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003000103
gene id: 510516:AO090003000103
uniprot id: Q2UM81
names: Similarity
messages: Belongs to the cullin family.

510516:AO090138000079
gene id: 510516:AO090138000079
uniprot id: Q2U1V8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090003001416
gene id: 510516:AO090003001416
uniprot id: Q2UIZ5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000127
gene id: 510516:AO090023000127
uniprot id: Q2UIB0
names: Similarity
messages: Belongs to the IlvD/Edd family.

510516:AO090020000179
gene id: 510516:AO090020000179
uniprot id: Q2U4W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Cytoplasm
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.

510516:AO090701000214
gene id: 510516:AO090701000214
uniprot id: Q2U913
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Cytoplasm

510516:AO090010000713
gene id: 510516:AO090010000713
uniprot id: Q2TW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090005001528
gene id: 510516:AO090005001528
uniprot id: Q2UPS5
names: Caution
names: Similarity
messages: Although strongly related to the peptide:N-glycanase enzyme, it lacks the conserved active site Cys in position 259, which is replaced by a Val residue suggesting that it has no activity.
messages: Belongs to the transglutaminase-like superfamily. PNGase family.

510516:AO090023000372
gene id: 510516:AO090023000372
uniprot id: Q2UHN8
names: Similarity
messages: Belongs to the peptidase S33 family.

510516:AO090124000052
gene id: 510516:AO090124000052
uniprot id: Q2U764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

510516:AO090011000378
gene id: 510516:AO090011000378
uniprot id: Q2U0M6
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Expression is highly up-regulated in azole resistant strains and in the presence of miconazole.
messages: Leads to strong miconazole susceptibility.
messages: Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:30011258). Confers resistance to miconazole and clotrimazole (PubMed:30011258).

510516:AO090012000584
gene id: 510516:AO090012000584
uniprot id: Q2UCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

510516:AO090003000018
gene id: 510516:AO090003000018
uniprot id: Q2UMF7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

510516:AO090023000668
gene id: 510516:AO090023000668
uniprot id: Q2UGX9
names: Similarity
messages: Belongs to the synembryn family.

510516:AO090001000524
gene id: 510516:AO090001000524
uniprot id: Q2UN32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

510516:AO090011000707
gene id: 510516:AO090011000707
uniprot id: Q2TZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

510516:AO090003000126
gene id: 510516:AO090003000126
uniprot id: Q2UM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Membrane

510516:AO090003000439
gene id: 510516:AO090003000439
uniprot id: Q2ULE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

510516:AO090020000357
gene id: 510516:AO090020000357
uniprot id: Q2U4G1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090012000401
gene id: 510516:AO090012000401
uniprot id: Q2UCY1
names: Similarity
messages: Belongs to the palC family.

510516:AO090003000921
gene id: 510516:AO090003000921
uniprot id: Q2UK78
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

510516:AO090003001408
gene id: 510516:AO090003001408
uniprot id: Q2UJ03
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

510516:AO090003000895
gene id: 510516:AO090003000895
uniprot id: Q2UKA2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

510516:AO090012000565
gene id: 510516:AO090012000565
uniprot id: Q2UCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090023000149
gene id: 510516:AO090023000149
uniprot id: Q2UI89
names: Similarity
messages: Belongs to the GST superfamily.

510516:AO090003000505
gene id: 510516:AO090003000505
uniprot id: Q2UL89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
messages: Cytoplasm
messages: Nucleus

510516:AO090020000013
gene id: 510516:AO090020000013
uniprot id: Q2U5A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
messages: Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
messages: P-body
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

510516:AO090005001602
gene id: 510516:AO090005001602
uniprot id: Q2UPK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable lipid hydrolase.

510516:AO090010000514
gene id: 510516:AO090010000514
uniprot id: Q2TWL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

510516:AO090009000672
gene id: 510516:AO090009000672
uniprot id: Q2UTM6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

510516:AO090023000760
gene id: 510516:AO090023000760
uniprot id: Q2UGQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

510516:AO090023000011
gene id: 510516:AO090023000011
uniprot id: Q2UIL4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090005000648
gene id: 510516:AO090005000648
uniprot id: Q2URX9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

510516:AO090023000812
gene id: 510516:AO090023000812
uniprot id: Q2UGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome. Interacts (via UBL domain) with mdn1 (via VWFA/MIDAS domain).
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

510516:AO090020000674
gene id: 510516:AO090020000674
uniprot id: Q2U3P7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090009000630
gene id: 510516:AO090009000630
uniprot id: Q2UTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

510516:AO090023000133
gene id: 510516:AO090023000133
uniprot id: Q2UIA4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000556
gene id: 510516:AO090012000556
uniprot id: Q2UCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane

510516:AO090026000097
gene id: 510516:AO090026000097
uniprot id: Q2UFS2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

510516:AO090023000039
gene id: 510516:AO090023000039
uniprot id: Q2UII8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001086
gene id: 510516:AO090005001086
uniprot id: Q2UQV5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090010000744
gene id: 510516:AO090010000744
uniprot id: Q2TW12
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090026000517
gene id: 510516:AO090026000517
uniprot id: Q2UER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

510516:AO090005001045
gene id: 510516:AO090005001045
uniprot id: Q2UQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.
messages: Nucleus

510516:AO090038000528
gene id: 510516:AO090038000528
uniprot id: Q2U2B2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090011000673
gene id: 510516:AO090011000673
uniprot id: Q2TZY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).
messages: Secreted

510516:AO090124000047
gene id: 510516:AO090124000047
uniprot id: Q2U768
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Homotetramer.

510516:AO090102000198
gene id: 510516:AO090102000198
uniprot id: Q2UAX1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000365
gene id: 510516:AO090026000365
uniprot id: Q2UF36
names: Subcellular Location Annotation
messages: Membrane

510516:AO090009000049
gene id: 510516:AO090009000049
uniprot id: Q2UV47
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000089
gene id: 510516:AO090020000089
uniprot id: Q2U537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

510516:AO090026000033
gene id: 510516:AO090026000033
uniprot id: Q2UFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090026000224
gene id: 510516:AO090026000224
uniprot id: Q2UFF9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001097
gene id: 510516:AO090003001097
uniprot id: Q2UJS3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Belongs to the NRP synthetase family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

510516:AO090023000697
gene id: 510516:AO090023000697
uniprot id: Q2UGV3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090701000600
gene id: 510516:AO090701000600
uniprot id: Q2U824
names: Similarity
messages: Belongs to the tryptophan dimethylallyltransferase family.

510516:AO090010000219
gene id: 510516:AO090010000219
uniprot id: Q2TXA7
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Expression is highly up-regulated in azole resistant strains and in the presence of miconazole.
messages: Leads to slight miconazole susceptibility.
messages: Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:30011258). Confers resistance to miconazole and clotrimazole (PubMed:30011258).

510516:AO090005000044
gene id: 510516:AO090005000044
uniprot id: Q2UTF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090102000559
gene id: 510516:AO090102000559
uniprot id: Q2UA37
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

510516:AO090010000160
gene id: 510516:AO090010000160
uniprot id: Q2TXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. CAR1 family.
messages: MFS-type transporter; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone.
messages: Membrane

510516:AO090023000455
gene id: 510516:AO090023000455
uniprot id: Q2UHG5
names: Similarity
messages: Belongs to the PrpF family.

510516:AO090103000178
gene id: 510516:AO090103000178
uniprot id: Q2TYN3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

510516:AO090010000673
gene id: 510516:AO090010000673
uniprot id: Q2TW76
names: Similarity
messages: Belongs to the SUA5 family.

510516:AO090003000845
gene id: 510516:AO090003000845
uniprot id: Q2UKE1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090701000077
gene id: 510516:AO090701000077
uniprot id: Q2U9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

510516:AO090023000890
gene id: 510516:AO090023000890
uniprot id: Q2UGC8
names: Similarity
messages: Belongs to the RAD52 family.

510516:AO090009000374
gene id: 510516:AO090009000374
uniprot id: Q2UUC2
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090012000342
gene id: 510516:AO090012000342
uniprot id: Q2UD30
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090701000108
gene id: 510516:AO090701000108
uniprot id: Q2U9A5
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

510516:AO090026000256
gene id: 510516:AO090026000256
uniprot id: Q2UFC8
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090003001032
gene id: 510516:AO090003001032
uniprot id: Q2UJX7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

510516:AO090005001232
gene id: 510516:AO090005001232
uniprot id: Q2UQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Membrane

510516:AO090120000210
gene id: 510516:AO090120000210
uniprot id: Q2U6J5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

510516:AO090011000625
gene id: 510516:AO090011000625
uniprot id: Q2U018
names: Similarity
messages: Belongs to the SPT2 family.

510516:AO090011000469
gene id: 510516:AO090011000469
uniprot id: Q2U0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

510516:AO090010000612
gene id: 510516:AO090010000612
uniprot id: Q2TWD0
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

510516:AO090005001109
gene id: 510516:AO090005001109
uniprot id: Q2UQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

510516:AO090001000692
gene id: 510516:AO090001000692
uniprot id: Q2UMN3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000291
gene id: 510516:AO090020000291
uniprot id: Q2U4L5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

510516:AO090020000699
gene id: 510516:AO090020000699
uniprot id: Q2U3M3
names: Similarity
messages: Belongs to the DSD1 family.

510516:AO090009000698
gene id: 510516:AO090009000698
uniprot id: Q2UTK2
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

510516:AO090120000196
gene id: 510516:AO090120000196
uniprot id: P0C1B3
names: Biotechnology
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Binds 2 calcium ions per subunit (PubMed:6609921, PubMed:9283074, PubMed:16880540). Calcium is inhibitory at high concentrations.
messages: Monomer.
messages: Secreted
messages: Used in the brewing industry to increase the fermentability of beer worts (including those made from unmalted cereals), in the starch industry to make high maltose and high DE syrups (starch saccharification), in the alcohol industry to reduce fermentation time, in the cereal food industry for flour supplementation and improvement of chilled and frozen dough, and in the forestry industry for low-temperature modification of starch. Sold under the name Fungamyl by Novozymes.

510516:AO090023000096
gene id: 510516:AO090023000096
uniprot id: Q2UID7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090120000327
gene id: 510516:AO090120000327
uniprot id: Q2U696
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus
messages: Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.

510516:AO090012000090
gene id: 510516:AO090012000090
uniprot id: Q2UDP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090005000471
gene id: 510516:AO090005000471
uniprot id: Q2USD6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000435
gene id: 510516:AO090012000435
uniprot id: Q2UCV2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090005000447
gene id: 510516:AO090005000447
uniprot id: P80402
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily.
messages: Has an absolute substrate specificity for 2,3-DHBA.
messages: Homotetramer.

510516:AO090009000090
gene id: 510516:AO090009000090
uniprot id: Q2UV15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003000570
gene id: 510516:AO090003000570
uniprot id: Q2UL30
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

510516:AO090120000215
gene id: 510516:AO090120000215
uniprot id: Q2U6J1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

510516:AO090102000150
gene id: 510516:AO090102000150
uniprot id: Q2UB16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090012000872
gene id: 510516:AO090012000872
uniprot id: Q2UBT5
names: Similarity
messages: Belongs to the VPS37 family.

510516:AO090138000010
gene id: 510516:AO090138000010
uniprot id: Q2U214
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

510516:AO090010000132
gene id: 510516:AO090010000132
uniprot id: Q2TXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Mitochondrion outer membrane

510516:AO090026000134
gene id: 510516:AO090026000134
uniprot id: Q2UFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Preautophagosomal structure membrane

510516:AO090701000015
gene id: 510516:AO090701000015
uniprot id: Q2U9I7
names: Similarity
messages: Belongs to the UPF0357 family.

510516:AO090012000573
gene id: 510516:AO090012000573
uniprot id: Q2UCI6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

510516:AO090102000614
gene id: 510516:AO090102000614
uniprot id: Q2U9Y6
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090020000019
gene id: 510516:AO090020000019
uniprot id: Q2U598
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090038000610
gene id: 510516:AO090038000610
uniprot id: Q2U242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

510516:AO090120000355
gene id: 510516:AO090120000355
uniprot id: Q2U672
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000870
gene id: 510516:AO090011000870
uniprot id: Q2TZF6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000996
gene id: 510516:AO090005000996
uniprot id: Q2UR29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization (By similarity).
messages: cytoskeleton

510516:AO090005000816
gene id: 510516:AO090005000816
uniprot id: Q2URI4
names: Similarity
messages: Belongs to the asparaginase 1 family.

510516:AO090010000520
gene id: 510516:AO090010000520
uniprot id: Q2TWK6
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090023000382
gene id: 510516:AO090023000382
uniprot id: Q2UHN1
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090009000558
gene id: 510516:AO090009000558
uniprot id: Q2UTX1
names: Similarity
messages: Belongs to the glutamine synthetase family.

510516:AO090026000136
gene id: 510516:AO090026000136
uniprot id: Q2UFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

510516:AO090012000770
gene id: 510516:AO090012000770
uniprot id: Q2UC26
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090003001410
gene id: 510516:AO090003001410
uniprot id: Q2UJ01
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Monomer.

510516:AO090005001630
gene id: 510516:AO090005001630
uniprot id: Q2UPI3
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

510516:AO090102000355
gene id: 510516:AO090102000355
uniprot id: Q2UAJ9
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

510516:AO090011000917
gene id: 510516:AO090011000917
uniprot id: Q2TZB9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

510516:AO090102000393
gene id: 510516:AO090102000393
uniprot id: Q2UAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

510516:AO090012001021
gene id: 510516:AO090012001021
uniprot id: Q2UBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

510516:AO090023000569
gene id: 510516:AO090023000569
uniprot id: Q2UH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

510516:AO090701000172
gene id: 510516:AO090701000172
uniprot id: Q2U951
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090011000114
gene id: 510516:AO090011000114
uniprot id: Q2U198
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000205
gene id: 510516:AO090010000205
uniprot id: Q2TXC0
names: Similarity
messages: Belongs to the peptidase C12 family.

510516:AO090001000042
gene id: 510516:AO090001000042
uniprot id: Q2UPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Dipeptidase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
messages: Membrane

510516:AO090009000691
gene id: 510516:AO090009000691
uniprot id: Q2UTK8
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

510516:AO090012000888
gene id: 510516:AO090012000888
uniprot id: Q2UBS2
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

510516:AO090023000099
gene id: 510516:AO090023000099
uniprot id: Q2UID4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

510516:AO090103000118
gene id: 510516:AO090103000118
uniprot id: Q2TYT4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090023000142
gene id: 510516:AO090023000142
uniprot id: Q2UI95
names: Similarity
messages: Belongs to the GcvT family.

510516:AO090701000397
gene id: 510516:AO090701000397
uniprot id: Q2U8K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).
messages: Associates with the nuclear pore complex.
messages: Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
messages: Cytoplasm
messages: Nucleus membrane
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nuclear pore complex

510516:AO090009000579
gene id: 510516:AO090009000579
uniprot id: Q2UTV2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090206000026
gene id: 510516:AO090206000026
uniprot id: Q2PIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

510516:AO090005000337
gene id: 510516:AO090005000337
uniprot id: Q2USQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

510516:AO090009000707
gene id: 510516:AO090009000707
uniprot id: Q2UTJ6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

510516:AO090166000079
gene id: 510516:AO090166000079
uniprot id: Q2U9N5
names: Similarity
messages: Belongs to the tannase family.

510516:AO090010000730
gene id: 510516:AO090010000730
uniprot id: Q2TW26
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090012000496
gene id: 510516:AO090012000496
uniprot id: Q2UCP9
uniprot id: Q76MU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

510516:AO090701000208
gene id: 510516:AO090701000208
uniprot id: Q2U919
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

510516:AO090020000158
gene id: 510516:AO090020000158
uniprot id: Q2U4Y0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

510516:AO090038000449
gene id: 510516:AO090038000449
uniprot id: Q2U2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Membrane

510516:AO090001000500
gene id: 510516:AO090001000500
uniprot id: Q2UN54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

510516:AO090120000141
gene id: 510516:AO090120000141
uniprot id: Q2U6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090120000044
gene id: 510516:AO090120000044
uniprot id: Q2U6Y4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090005000878
gene id: 510516:AO090005000878
uniprot id: Q2URD0
names: Similarity
messages: Belongs to the BRX1 family.

510516:AO090003000687
gene id: 510516:AO090003000687
uniprot id: Q2UKT1
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

510516:AO090026000543
gene id: 510516:AO090026000543
uniprot id: Q2UEP1
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

510516:AO090026000235
gene id: 510516:AO090026000235
uniprot id: Q2UFE9
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000209
gene id: 510516:AO090011000209
uniprot id: Q2U117
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090001000728
gene id: 510516:AO090001000728
uniprot id: Q2UMJ7
names: Similarity
messages: Belongs to the actin family.

510516:AO090003001373
gene id: 510516:AO090003001373
uniprot id: Q2UJ34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000473
gene id: 510516:AO090011000473
uniprot id: Q2U0E2
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090120000175
gene id: 510516:AO090120000175
uniprot id: Q2U6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

510516:AO090003000477
gene id: 510516:AO090003000477
uniprot id: Q2ULB1
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

510516:AO090010000760
gene id: 510516:AO090010000760
uniprot id: Q2TVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

510516:AO090701000589
gene id: 510516:AO090701000589
uniprot id: Q2U834
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

510516:AO090012000444
gene id: 510516:AO090012000444
uniprot id: Q2UCU4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

510516:AO090038000416
gene id: 510516:AO090038000416
uniprot id: Q2U2K9
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090701000226
gene id: 510516:AO090701000226
uniprot id: Q2U902
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

510516:AO090001000237
gene id: 510516:AO090001000237
uniprot id: Q2UNT7
names: Disruption Phenotype
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the velvet family. VeA subfamily.
messages: Component of the heterotrimeric velvet complex composed of laeA, veA and velB; VeA acting as a bridging protein between laeA and velB (By similarity).
messages: Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity). The velvet complex hat acts as a global regulator for secondary metabolite gene expression (PubMed:20541108). Controls the expression of the penicillin gene cluster (PubMed:20541108).
messages: Cytoplasm
messages: Nucleus
messages: Reduces the production of penicillin (PubMed:20541108).
messages: The C-terminal PEST domain is a region rich in proline, glutamic acid, serine and threonine residues that is required for the light-dependent regulation of development and secondary metabolism (By similarity).

510516:AO090038000096
gene id: 510516:AO090038000096
uniprot id: Q2U3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

510516:AO090026000581
gene id: 510516:AO090026000581
uniprot id: Q2UEK5
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: Leads to the loss of intermediates such as confertifolin.
messages: Membrane

510516:AO090010000705
gene id: 510516:AO090010000705
uniprot id: Q2TW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

510516:AO090038000206
gene id: 510516:AO090038000206
uniprot id: Q2U337
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000483
gene id: 510516:AO090011000483
uniprot id: Q2U0D5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090023000654
gene id: 510516:AO090023000654
uniprot id: Q2UGZ1
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

510516:AO090012000931
gene id: 510516:AO090012000931
uniprot id: Q2UBN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

510516:AO090010000312
gene id: 510516:AO090010000312
uniprot id: Q2TX28
names: Similarity
messages: Belongs to the BolA/IbaG family.

510516:AO090023000504
gene id: 510516:AO090023000504
uniprot id: Q2UHC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090001000550
gene id: 510516:AO090001000550
uniprot id: Q2UN06
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

510516:AO090102000165
gene id: 510516:AO090102000165
uniprot id: Q2UB01
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Abolishes the production of 2,4'-dihydroxy-3'-methoxypropiophenone and 4'-hydroxy-3'-methoxypropiophenone.
messages: Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554). The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554). Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554). During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable). O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable). Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable). PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Membrane

510516:AO090102000627
gene id: 510516:AO090102000627
uniprot id: Q2U9X4
names: Similarity
messages: Belongs to the citrate synthase family.

510516:AO090010000330
gene id: 510516:AO090010000330
uniprot id: Q2TX11
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090009000014
gene id: 510516:AO090009000014
uniprot id: Q2UV76
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090020000618
gene id: 510516:AO090020000618
uniprot id: Q2U3U2
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

510516:AO090026000513
gene id: 510516:AO090026000513
uniprot id: Q2UER5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

510516:AO090001000167
gene id: 510516:AO090001000167
uniprot id: Q2UNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

510516:AO090005001649
gene id: 510516:AO090005001649
uniprot id: Q2UPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

510516:AO090001000065
gene id: 510516:AO090001000065
uniprot id: Q2UP90
names: Subcellular Location Annotation
messages: Membrane

510516:AO090206000094
gene id: 510516:AO090206000094
uniprot id: Q2PIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090038000434
gene id: 510516:AO090038000434
uniprot id: Q2U2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090701000552
gene id: 510516:AO090701000552
uniprot id: Q2U865
names: Subcellular Location Annotation
messages: Membrane

510516:AO090138000004
gene id: 510516:AO090138000004
uniprot id: Q2U220
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090102000555
gene id: 510516:AO090102000555
uniprot id: Q2UA41
names: Similarity
messages: Belongs to the thymidylate kinase family.

510516:AO090003000963
gene id: 510516:AO090003000963
uniprot id: Q2UK39
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

510516:AO090003000235
gene id: 510516:AO090003000235
uniprot id: Q2ULX2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000588
gene id: 510516:AO090701000588
uniprot id: Q2U835
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090003000478
gene id: 510516:AO090003000478
uniprot id: Q2ULB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

510516:AO090011000036
gene id: 510516:AO090011000036
uniprot id: Q2U1G7
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M36 family.
messages: Binds 1 zinc ion per subunit.
messages: Expression is controlled by the prtT transcription factor.
messages: Secreted
messages: Secreted metalloproteinase that allows assimilation of proteinaceous substrates.

510516:AO090023000161
gene id: 510516:AO090023000161
uniprot id: P35335
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
messages: Secreted

510516:AO090011000055
gene id: 510516:AO090011000055
uniprot id: Q2U1F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

510516:AO090009000686
gene id: 510516:AO090009000686
uniprot id: Q2UTL3
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

510516:AO090012000617
gene id: 510516:AO090012000617
uniprot id: Q2UCF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

510516:AO090023000314
gene id: 510516:AO090023000314
uniprot id: Q2UHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

510516:AO090012000752
gene id: 510516:AO090012000752
uniprot id: Q2UC40
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Homotetramer.

510516:AO090005001282
gene id: 510516:AO090005001282
uniprot id: Q2UQE5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005001248
gene id: 510516:AO090005001248
uniprot id: Q2UQH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

510516:AO090003001461
gene id: 510516:AO090003001461
uniprot id: Q2UIV6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

510516:AO090010000062
gene id: 510516:AO090010000062
uniprot id: Q2TXP7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000418
gene id: 510516:AO090120000418
uniprot id: Q2U616
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Expression is barely detectable at the basal hyphal growth phase but induced during conidial development (PubMed:18448366).
messages: Leads to weak conidia formation on hyperosmotic medium (PubMed:18448366).
messages: Nucleus
messages: Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development and stress response through direct binding to their promoters (PubMed:18448366). Particularly involved in the resistance to oxidative stress in asexual conidiospores (PubMed:18448366).

510516:AO090701000235
gene id: 510516:AO090701000235
uniprot id: Q2U8Z3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

510516:AO090005000420
gene id: 510516:AO090005000420
uniprot id: Q2USH9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090020000073
gene id: 510516:AO090020000073
uniprot id: Q2U549
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090026000346
gene id: 510516:AO090026000346
uniprot id: Q2UF51
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090005001530
gene id: 510516:AO090005001530
uniprot id: Q2UPS3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

510516:AO090026000614
gene id: 510516:AO090026000614
uniprot id: Q2UEH7
names: Disruption Phenotype
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: Results in a hypersensitivity to miconazole.
messages: Transcription factor that regulates expression of the genes related to resistance to azole compounds.

510516:AO090005000919
gene id: 510516:AO090005000919
uniprot id: Q2UR92
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

510516:AO090005001354
gene id: 510516:AO090005001354
uniprot id: Q2UQ84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

510516:AO090001000665
gene id: 510516:AO090001000665
uniprot id: Q2UMQ4
names: Similarity
messages: Belongs to the CEF1 family.

510516:AO090038000122
gene id: 510516:AO090038000122
uniprot id: Q2U3A3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

510516:AO090005001092
gene id: 510516:AO090005001092
uniprot id: Q2UQV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

510516:AO090009000294
gene id: 510516:AO090009000294
uniprot id: Q2UUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

510516:AO090003001409
gene id: 510516:AO090003001409
uniprot id: Q2UJ02
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090011000825
gene id: 510516:AO090011000825
uniprot id: Q2TZJ8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

510516:AO090009000380
gene id: 510516:AO090009000380
uniprot id: Q2UUB6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000436
gene id: 510516:AO090005000436
uniprot id: Q2USG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

510516:AO090038000339
gene id: 510516:AO090038000339
uniprot id: Q2U2S4
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090026000283
gene id: 510516:AO090026000283
uniprot id: Q2UFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

510516:AO090005000034
gene id: 510516:AO090005000034
uniprot id: Q2UTG0
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

510516:AO090038000400
gene id: 510516:AO090038000400
uniprot id: Q2U2M2
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090120000341
gene id: 510516:AO090120000341
uniprot id: Q2U684
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090003001133
gene id: 510516:AO090003001133
uniprot id: Q2UJP1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

510516:AO090003000239
gene id: 510516:AO090003000239
uniprot id: Q2ULW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090003000506
gene id: 510516:AO090003000506
uniprot id: Q2UL88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

510516:AO090003001199
gene id: 510516:AO090003001199
uniprot id: Q2UJI4
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090010000669
gene id: 510516:AO090010000669
uniprot id: Q2TW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRI1 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090120000370
gene id: 510516:AO090120000370
uniprot id: Q2U658
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

510516:AO090023000110
gene id: 510516:AO090023000110
uniprot id: Q2UIC6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

510516:AO090009000621
gene id: 510516:AO090009000621
uniprot id: Q2UTR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090012000345
gene id: 510516:AO090012000345
uniprot id: Q2UD27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090005000781
gene id: 510516:AO090005000781
uniprot id: Q2URL4
names: Similarity
messages: Belongs to the pyridoxine kinase family.

510516:AO090038000356
gene id: 510516:AO090038000356
uniprot id: Q2U2Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

510516:AO090124000026
gene id: 510516:AO090124000026
uniprot id: Q2U787
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000304
gene id: 510516:AO090011000304
uniprot id: Q2U0U2
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090010000582
gene id: 510516:AO090010000582
uniprot id: Q2TWF5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

510516:AO090003001381
gene id: 510516:AO090003001381
uniprot id: Q2UJ26
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000797
gene id: 510516:AO090701000797
uniprot id: Q2U7L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

510516:AO090003000752
gene id: 510516:AO090003000752
uniprot id: Q2UKM2
names: Similarity
messages: Belongs to the DapA family.

510516:AO090103000132
gene id: 510516:AO090103000132
uniprot id: Q2TYS1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003000546
gene id: 510516:AO090003000546
uniprot id: Q2UL52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

510516:AO090005000812
gene id: 510516:AO090005000812
uniprot id: Q2URI7
names: Similarity
messages: Belongs to the WrbA family.

510516:AO090701000280
gene id: 510516:AO090701000280
uniprot id: Q2U8V3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090009000356
gene id: 510516:AO090009000356
uniprot id: Q2UUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
messages: Secreted

510516:AO090012000993
gene id: 510516:AO090012000993
uniprot id: Q2UBH9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090113000004
gene id: 510516:AO090113000004
uniprot id: Q2U5U3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

510516:AO090103000481
gene id: 510516:AO090103000481
uniprot id: Q2TXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090701000122
gene id: 510516:AO090701000122
uniprot id: Q2U994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090005001430
gene id: 510516:AO090005001430
uniprot id: Q2UQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090012000417
gene id: 510516:AO090012000417
uniprot id: Q2UCW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

510516:AO090020000669
gene id: 510516:AO090020000669
uniprot id: Q2U3Q1
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

510516:AO090120000340
gene id: 510516:AO090120000340
uniprot id: Q2U685
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUB1/samB family.
messages: Cytoplasm
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation (By similarity).

510516:AO090005001556
gene id: 510516:AO090005001556
uniprot id: Q2UPQ1
names: Similarity
messages: Belongs to the pyruvate kinase family.

510516:AO090026000485
gene id: 510516:AO090026000485
uniprot id: Q2UET8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000307
gene id: 510516:AO090701000307
uniprot id: Q2U8S8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090020000413
gene id: 510516:AO090020000413
uniprot id: Q2U4B3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

510516:AO090026000538
gene id: 510516:AO090026000538
uniprot id: Q2UEP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).
messages: Mitochondrion

510516:AO090001000015
gene id: 510516:AO090001000015
uniprot id: Q2UPD6
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090003001324
gene id: 510516:AO090003001324
uniprot id: Q2UJ80
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated once deposited into chromatin.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the vps72/swc2 subunit of the SWR1 chromatin remodeling complex. Interacts also with rbp1/DNA-directed RNA polymerase II largest subunit (By similarity).
messages: Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and spt15/TBP recruitment to the target genes. Involved in chromosome stability (By similarity).

510516:AO090003001376
gene id: 510516:AO090003001376
uniprot id: Q2UJ31
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090012000827
gene id: 510516:AO090012000827
uniprot id: Q2UBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

510516:AO090005000132
gene id: 510516:AO090005000132
uniprot id: Q2UT72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

510516:AO090003000885
gene id: 510516:AO090003000885
uniprot id: Q2UKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

510516:AO090012000271
gene id: 510516:AO090012000271
uniprot id: Q2UD90
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

510516:AO090009000197
gene id: 510516:AO090009000197
uniprot id: Q2UUS4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000498
gene id: 510516:AO090120000498
uniprot id: Q2U5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

510516:AO090012000624
gene id: 510516:AO090012000624
uniprot id: Q2UCE5
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

510516:AO090701000173
gene id: 510516:AO090701000173
uniprot id: Q2U950
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

510516:AO090026000664
gene id: 510516:AO090026000664
uniprot id: Q2UED4
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

510516:AO090011000229
gene id: 510516:AO090011000229
uniprot id: Q2U101
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090003000225
gene id: 510516:AO090003000225
uniprot id: Q2ULX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

510516:AO090038000054
gene id: 510516:AO090038000054
uniprot id: Q2U3F9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090102000298
gene id: 510516:AO090102000298
uniprot id: Q2UAP5
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090011000116
gene id: 510516:AO090011000116
uniprot id: Q2U196
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000312
gene id: 510516:AO090120000312
uniprot id: Q2U6B1
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.

510516:AO090038000452
gene id: 510516:AO090038000452
uniprot id: Q2U2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

510516:AO090026000133
gene id: 510516:AO090026000133
uniprot id: Q2UFN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.
messages: Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.
messages: Component of the SCF(sconB) E3 ubiquitin ligase complex.

510516:AO090011000493
gene id: 510516:AO090011000493
uniprot id: Q2U0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

510516:AO090010000700
gene id: 510516:AO090010000700
uniprot id: Q2TW54
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090026000804
gene id: 510516:AO090026000804
uniprot id: Q2UE10
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090010000186
gene id: 510516:AO090010000186
uniprot id: Q2TXD7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000109
gene id: 510516:AO090020000109
uniprot id: Q2U523
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least coq3, coq4, coq5, coq6, coq7 and coq9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

510516:AO090003000001
gene id: 510516:AO090003000001
uniprot id: Q2UMH4
names: Similarity
messages: Belongs to the TRM112 family.

510516:AO090001000207
gene id: 510516:AO090001000207
uniprot id: Q2UNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. FaeA family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin (By similarity).
messages: Secreted

510516:AO090023001006
gene id: 510516:AO090023001006
uniprot id: Q2UG25
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

510516:AO090103000435
gene id: 510516:AO090103000435
uniprot id: Q2TY09
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090010000684
gene id: 510516:AO090010000684
uniprot id: Q2TW69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 36 family.
messages: Homotetramer.
messages: Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
messages: Secreted

510516:AO090003000922
gene id: 510516:AO090003000922
uniprot id: Q2UK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

510516:AO090005000090
gene id: 510516:AO090005000090
uniprot id: Q2UTB1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090005001121
gene id: 510516:AO090005001121
uniprot id: Q2UQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

510516:AO090005001150
gene id: 510516:AO090005001150
uniprot id: Q2UQQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

510516:AO090003000121
gene id: 510516:AO090003000121
uniprot id: Q2UM66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

510516:AO090005001523
gene id: 510516:AO090005001523
uniprot id: Q2UPT0
names: Function
names: Subunit
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
messages: Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.

510516:AO090038000296
gene id: 510516:AO090038000296
uniprot id: Q2U2W1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

510516:AO090701000281
gene id: 510516:AO090701000281
uniprot id: Q2U8V2
names: Similarity
messages: Belongs to the cyclin family.

510516:AO090020000122
gene id: 510516:AO090020000122
uniprot id: Q2U512
names: Similarity
messages: Belongs to the SUI1 family.

510516:AO090113000144
gene id: 510516:AO090113000144
uniprot id: Q2U5H2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090120000124
gene id: 510516:AO090120000124
uniprot id: Q2U6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

510516:AO090005000742
gene id: 510516:AO090005000742
uniprot id: Q2URP4
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090120000021
gene id: 510516:AO090120000021
uniprot id: Q2U705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090023000065
gene id: 510516:AO090023000065
uniprot id: Q2UIG4
names: Similarity
messages: Belongs to the Gfa family.

510516:AO090011000715
gene id: 510516:AO090011000715
uniprot id: Q2TZU7
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.

510516:AO090011000905
gene id: 510516:AO090011000905
uniprot id: Q2TZC9
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

510516:AO090020000614
gene id: 510516:AO090020000614
uniprot id: Q2U3U5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000345
gene id: 510516:AO090023000345
uniprot id: Q2UHR3
names: Similarity
messages: Belongs to the transketolase family.

510516:AO090009000148
gene id: 510516:AO090009000148
uniprot id: Q2UUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Cell membrane
messages: Membrane

510516:AO090102000551
gene id: 510516:AO090102000551
uniprot id: Q2UA44
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

510516:AO090038000456
gene id: 510516:AO090038000456
uniprot id: Q2U2H3
names: Similarity
messages: Belongs to the UPF0507 family.

510516:AO090001000135
gene id: 510516:AO090001000135
uniprot id: Q2UP30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M35 family.
messages: Binds 1 zinc ion per subunit.
messages: Secreted
messages: Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).

510516:AO090003000936
gene id: 510516:AO090003000936
uniprot id: Q2UK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

510516:AO090026000315
gene id: 510516:AO090026000315
uniprot id: Q2UF78
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090012000686
gene id: 510516:AO090012000686
uniprot id: Q2UC95
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

510516:AO090005001204
gene id: 510516:AO090005001204
uniprot id: Q2UQK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

510516:AO090102000072
gene id: 510516:AO090102000072
uniprot id: Q2UB83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).
messages: Secreted

510516:AO090003001025
gene id: 510516:AO090003001025
uniprot id: Q2UJY3
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090026000708
gene id: 510516:AO090026000708
uniprot id: Q2UE97
names: Similarity
messages: Belongs to the thioredoxin family.

510516:AO090009000412
gene id: 510516:AO090009000412
uniprot id: Q2UU90
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

510516:AO090005000409
gene id: 510516:AO090005000409
uniprot id: Q2USI8
names: Similarity
messages: Belongs to the SUN family.

510516:AO090206000108
gene id: 510516:AO090206000108
uniprot id: Q2PIQ7
names: Similarity
messages: Belongs to the MTFP1 family.

510516:AO090206000077
gene id: 510516:AO090206000077
uniprot id: Q2PIT0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

510516:AO090023000787
gene id: 510516:AO090023000787
uniprot id: Q2UGM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090012000493
gene id: 510516:AO090012000493
uniprot id: Q2UCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

510516:AO090003001541
gene id: 510516:AO090003001541
uniprot id: Q2UIP0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000938
gene id: 510516:AO090003000938
uniprot id: Q2UK63
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

510516:AO090005000360
gene id: 510516:AO090005000360
uniprot id: Q2USN2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090009000557
gene id: 510516:AO090009000557
uniprot id: Q2UTX2
names: Similarity
messages: Belongs to the malate synthase family.

510516:AO090012000279
gene id: 510516:AO090012000279
uniprot id: Q2UD82
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

510516:AO090005000166
gene id: 510516:AO090005000166
uniprot id: Q2UT42
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001290
gene id: 510516:AO090005001290
uniprot id: Q2UQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

510516:AO090011000453
gene id: 510516:AO090011000453
uniprot id: Q2U0G1
names: Function
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.

510516:AO090003000186
gene id: 510516:AO090003000186
uniprot id: Q2UM12
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

510516:AO090701000495
gene id: 510516:AO090701000495
uniprot id: Q2U8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

510516:AO090003000017
gene id: 510516:AO090003000017
uniprot id: Q2UMF8
names: Similarity
messages: Belongs to the FAH family.

510516:AO090102000067
gene id: 510516:AO090102000067
uniprot id: Q2UB87
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

510516:AO090026000435
gene id: 510516:AO090026000435
uniprot id: Q2UEX8
names: Similarity
messages: Belongs to the RMD1/sif2 family.

510516:AO090023000615
gene id: 510516:AO090023000615
uniprot id: Q2UH24
names: Similarity
messages: Belongs to the tannase family.

510516:AO090701000378
gene id: 510516:AO090701000378
uniprot id: Q2U8L8
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

510516:AO090166000054
gene id: 510516:AO090166000054
uniprot id: Q2U9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

510516:AO090120000106
gene id: 510516:AO090120000106
uniprot id: Q2U6T3
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090010000483
gene id: 510516:AO090010000483
uniprot id: Q96VA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

510516:AO090001000348
gene id: 510516:AO090001000348
uniprot id: Q2UNI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.

510516:AO090102000108
gene id: 510516:AO090102000108
uniprot id: Q2UB51
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

510516:AO090023000791
gene id: 510516:AO090023000791
uniprot id: Q2UGM1
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

510516:AO090010000493
gene id: 510516:AO090010000493
uniprot id: P46076
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M35 family.
messages: Binds 1 zinc ion per subunit.
messages: Metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine.

510516:AO090001000378
gene id: 510516:AO090001000378
uniprot id: Q2UNG3
names: Similarity
messages: Belongs to the Tom22 family.

510516:AO090020000134
gene id: 510516:AO090020000134
uniprot id: Q2U502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

510516:AO090003000654
gene id: 510516:AO090003000654
uniprot id: Q2UKV9
names: Similarity
messages: Belongs to the argonaute family.

510516:AO090120000033
gene id: 510516:AO090120000033
uniprot id: Q2U6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

510516:AO090011000202
gene id: 510516:AO090011000202
uniprot id: Q2U124
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

510516:AO090012000782
gene id: 510516:AO090012000782
uniprot id: Q2UC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

510516:AO090001000559
gene id: 510516:AO090001000559
uniprot id: Q2UMZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

510516:AO090009000644
gene id: 510516:AO090009000644
uniprot id: Q2UTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

510516:AO090001000553
gene id: 510516:AO090001000553
uniprot id: Q2UN03
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

510516:AO090012000066
gene id: 510516:AO090012000066
uniprot id: Q2UDR3
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003001045
gene id: 510516:AO090003001045
uniprot id: Q2UJW6
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090102000493
gene id: 510516:AO090102000493
uniprot id: Q2UA91
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000937
gene id: 510516:AO090011000937
uniprot id: Q2TZA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: spindle

510516:AO090020000588
gene id: 510516:AO090020000588
uniprot id: Q2U3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal hydrophobin family.
messages: cell wall

510516:AO090003000462
gene id: 510516:AO090003000462
uniprot id: Q2ULC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).
messages: Membrane
messages: nucleolus

510516:AO090038000348
gene id: 510516:AO090038000348
uniprot id: Q2U2R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

510516:AO090005001532
gene id: 510516:AO090005001532
uniprot id: Q2UPS1
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005000892
gene id: 510516:AO090005000892
uniprot id: Q2URB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

510516:AO090701000727
gene id: 510516:AO090701000727
uniprot id: Q2U7S0
names: Similarity
messages: Belongs to the FUN14 family.

510516:AO090023000645
gene id: 510516:AO090023000645
uniprot id: Q2UGZ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

510516:AO090003000808
gene id: 510516:AO090003000808
uniprot id: Q2UKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

510516:AO090003000618
gene id: 510516:AO090003000618
uniprot id: Q2UKY5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

510516:AO090020000007
gene id: 510516:AO090020000007
uniprot id: Q2U5A8
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by esa1 to form H2AK4ac and H2AK7ac.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.
messages: Nucleus
messages: Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases mec1/ATR and tel1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
messages: The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-5; H2AK7ac = acetylated Lys-9; H2AS128ph = phosphorylated Ser-131.

510516:AO090120000004
gene id: 510516:AO090120000004
uniprot id: Q2U721
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

510516:AO090023000602
gene id: 510516:AO090023000602
uniprot id: Q2UH35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S9B family.
messages: Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
messages: Secreted

510516:AO090012000536
gene id: 510516:AO090012000536
uniprot id: Q2UCL7
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

510516:AO090120000424
gene id: 510516:AO090120000424
uniprot id: Q2U611
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

510516:AO090120000166
gene id: 510516:AO090120000166
uniprot id: Q2U6N4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000138
gene id: 510516:AO090005000138
uniprot id: Q2UT66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090166000117
gene id: 510516:AO090166000117
uniprot id: Q2U9K7
names: Similarity
messages: Belongs to the amidase family.

510516:AO090701000837
gene id: 510516:AO090701000837
uniprot id: Q2U7H5
names: Similarity
messages: Belongs to the Gfa family.

510516:AO090005001522
gene id: 510516:AO090005001522
uniprot id: Q2UPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

510516:AO090038000308
gene id: 510516:AO090038000308
uniprot id: Q2U2V2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

510516:AO090001000413
gene id: 510516:AO090001000413
uniprot id: Q2UND2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

510516:AO090138000161
gene id: 510516:AO090138000161
uniprot id: Q2U1N4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000253
gene id: 510516:AO090026000253
uniprot id: Q2UFD1
names: Similarity
messages: Belongs to the PrpD family.

510516:AO090001000512
gene id: 510516:AO090001000512
uniprot id: Q2UN43
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

510516:AO090010000225
gene id: 510516:AO090010000225
uniprot id: Q2TXA1
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

510516:AO090005001651
gene id: 510516:AO090005001651
uniprot id: Q2UPG5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

510516:AO090011000590
gene id: 510516:AO090011000590
uniprot id: Q2U048
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

510516:AO090023000864
gene id: 510516:AO090023000864
uniprot id: Q2UGF2
names: Similarity
messages: Belongs to the syntaxin family.

510516:AO090102000391
gene id: 510516:AO090102000391
uniprot id: Q2UAG8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

510516:AO090005001223
gene id: 510516:AO090005001223
uniprot id: Q2UQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090038000511
gene id: 510516:AO090038000511
uniprot id: Q2U2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

510516:AO090010000041
gene id: 510516:AO090010000041
uniprot id: Q2TXR3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090020000265
gene id: 510516:AO090020000265
uniprot id: Q2U4N7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

510516:AO090023000850
gene id: 510516:AO090023000850
uniprot id: Q2UGG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

510516:AO090011000369
gene id: 510516:AO090011000369
uniprot id: Q2U0N2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090011000743
gene id: 510516:AO090011000743
uniprot id: Q2TZS1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090023000884
gene id: 510516:AO090023000884
uniprot id: Q2UGD4
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090003000423
gene id: 510516:AO090003000423
uniprot id: Q2ULG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Mitochondrion
messages: Oligomer.

510516:AO090038000314
gene id: 510516:AO090038000314
uniprot id: Q2U2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

510516:AO090701000148
gene id: 510516:AO090701000148
uniprot id: Q2U969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

510516:AO090010000616
gene id: 510516:AO090010000616
uniprot id: Q2TWC7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090001000204
gene id: 510516:AO090001000204
uniprot id: Q2UNW7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000299
gene id: 510516:AO090026000299
uniprot id: Q2UF91
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090009000695
gene id: 510516:AO090009000695
uniprot id: Q2UTK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

510516:AO090102000174
gene id: 510516:AO090102000174
uniprot id: Q2UAZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

510516:AO090009000427
gene id: 510516:AO090009000427
uniprot id: Q2UU75
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000557
gene id: 510516:AO090102000557
uniprot id: Q2UA39
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

510516:AO090011000777
gene id: 510516:AO090011000777
uniprot id: Q2TZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

510516:AO090009000242
gene id: 510516:AO090009000242
uniprot id: Q2UUN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090005000813
gene id: 510516:AO090005000813
uniprot id: Q2URI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

510516:AO090011000408
gene id: 510516:AO090011000408
uniprot id: Q2U0K2
names: Cofactor
names: Disruption Phenotype
names: Domain
names: Function
names: Induction
names: Similarity
messages: Abolishes the production of heptelidic acid.
messages: Belongs to the terpene synthase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Sesquiterpene cyclase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing.
messages: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
messages: The expression is positively regulated by the 2 cluster-specific transcription factors hepR and hepS.

510516:AO090009000199
gene id: 510516:AO090009000199
uniprot id: Q2UUS2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

510516:AO090113000171
gene id: 510516:AO090113000171
uniprot id: Q2U5E9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

510516:AO090701000645
gene id: 510516:AO090701000645
uniprot id: Q2U7Y8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000017
gene id: 510516:AO090011000017
uniprot id: Q2U1I4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000030
gene id: 510516:AO090011000030
uniprot id: Q2U1H3
names: Subcellular Location Annotation
messages: Secreted

510516:AO090103000332
gene id: 510516:AO090103000332
uniprot id: Q2TYA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
messages: Vacuole

510516:AO090001000066
gene id: 510516:AO090001000066
uniprot id: Q2UP89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tannase family.
messages: Homodimer.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
messages: Secreted
messages: The calcium ion seen in the crystal structure is located far from the active site and appears to have a role in stabilization of the lid domain.

510516:AO090701000012
gene id: 510516:AO090701000012
uniprot id: Q2U9J0
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

510516:AO090012000627
gene id: 510516:AO090012000627
uniprot id: Q2UCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

510516:AO090120000293
gene id: 510516:AO090120000293
uniprot id: Q2U6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

510516:AO090012000916
gene id: 510516:AO090012000916
uniprot id: Q2UBP8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

510516:AO090012000933
gene id: 510516:AO090012000933
uniprot id: Q2UBN1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090103000011
gene id: 510516:AO090103000011
uniprot id: Q2TZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

510516:AO090005000561
gene id: 510516:AO090005000561
uniprot id: Q2US57
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

510516:AO090011000412
gene id: 510516:AO090011000412
uniprot id: Q2U0J9
names: Disruption Phenotype
names: Function
names: Similarity
messages: Abolishes the production of heptelidic acid.
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing.

510516:AO090005000050
gene id: 510516:AO090005000050
uniprot id: Q2UTE5
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090003001259
gene id: 510516:AO090003001259
uniprot id: Q2UJD7
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090026000181
gene id: 510516:AO090026000181
uniprot id: Q2UFJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090003001036
gene id: 510516:AO090003001036
uniprot id: P12547
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Expression is controlled by the prtT transcription factor.
messages: Secreted
messages: Secreted alkaline protease that allows assimilation of proteinaceous substrates.

510516:AO090038000009
gene id: 510516:AO090038000009
uniprot id: Q2U3J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

510516:AO090026000396
gene id: 510516:AO090026000396
uniprot id: Q2UF09
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000740
gene id: 510516:AO090011000740
uniprot id: Q2TZS4
names: Similarity
messages: Belongs to the paxB family.

510516:AO090005000773
gene id: 510516:AO090005000773
uniprot id: Q2URM0
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

510516:AO090124000079
gene id: 510516:AO090124000079
uniprot id: Q2U738
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

510516:AO090026000433
gene id: 510516:AO090026000433
uniprot id: Q2UEY0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000696
gene id: 510516:AO090020000696
uniprot id: Q2U3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090023000806
gene id: 510516:AO090023000806
uniprot id: Q2UGK6
names: Similarity
messages: Belongs to the PurH family.

510516:AO090005000472
gene id: 510516:AO090005000472
uniprot id: Q2USD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
messages: Secreted

510516:AO090020000057
gene id: 510516:AO090020000057
uniprot id: Q2U562
names: Similarity
messages: Belongs to the OSBP family.

510516:AO090023000756
gene id: 510516:AO090023000756
uniprot id: Q2UGQ4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

510516:AO090026000639
gene id: 510516:AO090026000639
uniprot id: Q2UEF4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

510516:AO090020000613
gene id: 510516:AO090020000613
uniprot id: Q2U3U6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090003001090
gene id: 510516:AO090003001090
uniprot id: Q2UJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

510516:AO090005001031
gene id: 510516:AO090005001031
uniprot id: Q2UR01
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

510516:AO090011000649
gene id: 510516:AO090011000649
uniprot id: Q2U001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090206000080
gene id: 510516:AO090206000080
uniprot id: Q2PIS7
names: Similarity
messages: Belongs to the amidase family.

510516:AO090026000569
gene id: 510516:AO090026000569
uniprot id: Q2UEL6
names: Similarity
messages: Belongs to the ketopantoate reductase family.

510516:AO090026000515
gene id: 510516:AO090026000515
uniprot id: Q2UER3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090011000358
gene id: 510516:AO090011000358
uniprot id: Q2U0P2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

510516:AO090009000522
gene id: 510516:AO090009000522
uniprot id: Q2UU00
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000398
gene id: 510516:AO090701000398
uniprot id: Q2U8K5
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

510516:AO090038000254
gene id: 510516:AO090038000254
uniprot id: Q2U2Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus
messages: Membrane

510516:AO090001000522
gene id: 510516:AO090001000522
uniprot id: Q2UN34
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

510516:AO090102000556
gene id: 510516:AO090102000556
uniprot id: Q2UA40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

510516:AO090005000074
gene id: 510516:AO090005000074
uniprot id: Q2UTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090701000090
gene id: 510516:AO090701000090
uniprot id: Q2U9C0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

510516:AO090011000414
gene id: 510516:AO090011000414
uniprot id: Q2U0J7
names: Disruption Phenotype
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Does not affect the biosynthesis of heptelidic acid.
messages: Glyceraldehyde-3-phosphate dehydrogenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing (PubMed:30466366). The GAPDPH hepG/gdpB shows much higher resistance to HA than the GAPDH gpdA located outside of the cluster, but it does not seem to act in self-resistance (PubMed:30466366).
messages: Homotetramer.

510516:AO090026000225
gene id: 510516:AO090026000225
uniprot id: Q2UFF8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

510516:AO090003000354
gene id: 510516:AO090003000354
uniprot id: Q2ULM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28A subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides.
messages: Monomer.
messages: Secreted

510516:AO090102000515
gene id: 510516:AO090102000515
uniprot id: Q2UA72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

510516:AO090005001434
gene id: 510516:AO090005001434
uniprot id: Q2UQ09
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003001255
gene id: 510516:AO090003001255
uniprot id: Q2UJE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

510516:AO090012001002
gene id: 510516:AO090012001002
uniprot id: Q2UBH2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000230
gene id: 510516:AO090120000230
uniprot id: Q2U6H9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000971
gene id: 510516:AO090003000971
uniprot id: Q2UK34
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000709
gene id: 510516:AO090701000709
uniprot id: Q2U7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

510516:AO090038000383
gene id: 510516:AO090038000383
uniprot id: Q2U2N6
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

510516:AO090012000051
gene id: 510516:AO090012000051
uniprot id: Q2UDS4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000264
gene id: 510516:AO090012000264
uniprot id: Q2UD96
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090010000218
gene id: 510516:AO090010000218
uniprot id: Q2TXA8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090009000288
gene id: 510516:AO090009000288
uniprot id: Q2UUJ8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090005001001
gene id: 510516:AO090005001001
uniprot id: Q2UR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

510516:AO090026000518
gene id: 510516:AO090026000518
uniprot id: Q2UER0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000176
gene id: 510516:AO090010000176
uniprot id: Q2TXE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090020000530
gene id: 510516:AO090020000530
uniprot id: Q2U417
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090020000056
gene id: 510516:AO090020000056
uniprot id: Q2U563
names: Similarity
messages: Belongs to the IFRD family.

510516:AO090003000414
gene id: 510516:AO090003000414
uniprot id: Q2ULH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090701000463
gene id: 510516:AO090701000463
uniprot id: Q2U8E2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000894
gene id: 510516:AO090011000894
uniprot id: Q2TZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

510516:AO090012000181
gene id: 510516:AO090012000181
uniprot id: Q2UDG5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090023000023
gene id: 510516:AO090023000023
uniprot id: Q2UIK3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000448
gene id: 510516:AO090701000448
uniprot id: Q2U8F7
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090005000844
gene id: 510516:AO090005000844
uniprot id: Q2URF9
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090026000003
gene id: 510516:AO090026000003
uniprot id: Q2UG11
names: Function
names: Similarity
messages: Belongs to the beta-cyclopiazonate dehydrogenase family.
messages: Beta-cyclopiazonate dehydrogenase involved in the synthesis of the fungal neurotoxin alpha-cyclopiazonic acid (CPA). CpaO carries out the dehydrogenation of beta-CPA to yield an unstable enimine product, which is captured by intramolecular cyclization to create the pentacyclic fused scaffold of alpha-cyclopiazonate.

510516:AO090011000717
gene id: 510516:AO090011000717
uniprot id: Q2TZU5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090003001431
gene id: 510516:AO090003001431
uniprot id: Q2UIY0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090012000602
gene id: 510516:AO090012000602
uniprot id: Q2UCG2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000392
gene id: 510516:AO090005000392
uniprot id: Q2USK4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090020000138
gene id: 510516:AO090020000138
uniprot id: Q2U4Z8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

510516:AO090020000338
gene id: 510516:AO090020000338
uniprot id: Q2U4H8
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

510516:AO090003000484
gene id: 510516:AO090003000484
uniprot id: Q2ULA5
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

510516:AO090010000444
gene id: 510516:AO090010000444
uniprot id: Q9HGZ0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

510516:AO090011000613
gene id: 510516:AO090011000613
uniprot id: Q2U027
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

510516:AO090020000622
gene id: 510516:AO090020000622
uniprot id: Q2U3T8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least bud32, cgi121, gon7, kae1 and pcc1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus
messages: This protein is considered an atypical serine/threonine kinase, because it lacks the conventional structural elements necessary for the substrate recognition as well as a lysine residue that in all other serine/threonine kinases participates in the catalytic event (By similarity). BUD32 has protein kinase activity in vitro, but in the context of the EKC/KEOPS complex, the catalytic subunit KAE1 switches the activity of BUD32 from kinase into ATPase (By similarity).
messages: telomere

510516:AO090026000580
gene id: 510516:AO090026000580
uniprot id: Q2UEK6
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
messages: Significantly reduces the production of deacetyl astellolides A and B.

510516:AO090120000224
gene id: 510516:AO090120000224
uniprot id: Q2U6I3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

510516:AO090011000204
gene id: 510516:AO090011000204
uniprot id: Q2U122
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000304
gene id: 510516:AO090020000304
uniprot id: Q2U4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

510516:AO090011000064
gene id: 510516:AO090011000064
uniprot id: Q2U1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090102000606
gene id: 510516:AO090102000606
uniprot id: Q2U9Z4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

510516:AO090003001089
gene id: 510516:AO090003001089
uniprot id: Q2UJT0
names: Similarity
messages: Belongs to the FBPase class 1 family.

510516:AO090010000229
gene id: 510516:AO090010000229
uniprot id: Q2TX98
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

510516:AO090011000024
gene id: 510516:AO090011000024
uniprot id: Q2U1H8
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090012000415
gene id: 510516:AO090012000415
uniprot id: Q2UCW9
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

510516:AO090023000509
gene id: 510516:AO090023000509
uniprot id: Q2UHB8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000693
gene id: 510516:AO090003000693
uniprot id: Q2UKS5
names: Similarity
messages: Belongs to the peptidase A1 family.

510516:AO090026000670
gene id: 510516:AO090026000670
uniprot id: Q2UEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

510516:AO090020000048
gene id: 510516:AO090020000048
uniprot id: Q2U570
names: Similarity
messages: Belongs to the isochorismatase family.

510516:AO090023000762
gene id: 510516:AO090023000762
uniprot id: Q2UGP8
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

510516:AO090020000047
gene id: 510516:AO090020000047
uniprot id: Q2U571
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000031
gene id: 510516:AO090701000031
uniprot id: Q2U9H3
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

510516:AO090102000368
gene id: 510516:AO090102000368
uniprot id: Q2UAI8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

510516:AO090701000880
gene id: 510516:AO090701000880
uniprot id: Q2U7D5
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

510516:AO090001000425
gene id: 510516:AO090001000425
uniprot id: Q2UNC0
names: Similarity
messages: Belongs to the CoA-transferase III family.

510516:AO090003000382
gene id: 510516:AO090003000382
uniprot id: Q2ULJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

510516:AO090023000796
gene id: 510516:AO090023000796
uniprot id: Q2UGL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090003001087
gene id: 510516:AO090003001087
uniprot id: Q2UJT1
names: Similarity
messages: Belongs to the AHA1 family.

510516:AO090010000710
gene id: 510516:AO090010000710
uniprot id: Q2TW45
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

510516:AO090003000839
gene id: 510516:AO090003000839
uniprot id: Q2UKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Membrane
messages: Probable lipid hydrolase.

510516:AO090023000893
gene id: 510516:AO090023000893
uniprot id: Q2UGC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
messages: Membrane

510516:AO090120000149
gene id: 510516:AO090120000149
uniprot id: Q2U6P7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).
messages: Belongs to the DEAD box helicase family. DECD subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

510516:AO090005000302
gene id: 510516:AO090005000302
uniprot id: Q2UST4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000425
gene id: 510516:AO090701000425
uniprot id: Q2U8H9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000980
gene id: 510516:AO090023000980
uniprot id: Q2UG48
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

510516:AO090023000571
gene id: 510516:AO090023000571
uniprot id: Q2UH61
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.

510516:AO090026000749
gene id: 510516:AO090026000749
uniprot id: Q2UE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

510516:AO090020000522
gene id: 510516:AO090020000522
uniprot id: Q2U424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion

510516:AO090038000552
gene id: 510516:AO090038000552
uniprot id: Q2U293
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).
messages: Secreted

510516:AO090001000697
gene id: 510516:AO090001000697
uniprot id: Q2UMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

510516:AO090103000456
gene id: 510516:AO090103000456
uniprot id: Q2TXY9
names: Similarity
messages: Belongs to the FMO family.

510516:AO090023000476
gene id: 510516:AO090023000476
uniprot id: Q2UHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

510516:AO090001000544
gene id: 510516:AO090001000544
uniprot id: Q2UN12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
messages: Secreted

510516:AO090020000298
gene id: 510516:AO090020000298
uniprot id: Q2U4K9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

510516:AO090113000110
gene id: 510516:AO090113000110
uniprot id: Q2U5K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with tah18. Interacts with mia40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial mia40-erv1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

510516:AO090003001385
gene id: 510516:AO090003001385
uniprot id: Q2UJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

510516:AO090120000026
gene id: 510516:AO090120000026
uniprot id: Q9HFA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.
messages: Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
messages: Secreted
messages: The promoter contains two 5'-GGCTAAA-3' sequences identified as binding sites for the xylanolytic transcriptional activator xlnR.

510516:AO090005001561
gene id: 510516:AO090005001561
uniprot id: Q2UPP6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

510516:AO090003001230
gene id: 510516:AO090003001230
uniprot id: Q2UJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

510516:AO090012000613
gene id: 510516:AO090012000613
uniprot id: Q2UCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

510516:AO090020000414
gene id: 510516:AO090020000414
uniprot id: Q2U4B2
names: Similarity
messages: Belongs to the AAA ATPase family.

510516:AO090005000221
gene id: 510516:AO090005000221
uniprot id: Q2UT02
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000666
gene id: 510516:AO090003000666
uniprot id: Q2UKU9
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090012000577
gene id: 510516:AO090012000577
uniprot id: Q2UCI4
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

510516:AO090120000261
gene id: 510516:AO090120000261
uniprot id: Q2U6F2
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090005001028
gene id: 510516:AO090005001028
uniprot id: Q2UR03
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000974
gene id: 510516:AO090003000974
uniprot id: Q2UK31
names: Similarity
messages: Belongs to the TMCO4 family.

510516:AO090011000113
gene id: 510516:AO090011000113
uniprot id: Q2U199
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).
messages: Secreted

510516:AO090701000400
gene id: 510516:AO090701000400
uniprot id: Q2U8K3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

510516:AO090005001516
gene id: 510516:AO090005001516
uniprot id: Q2UPT6
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090001000098
gene id: 510516:AO090001000098
uniprot id: Q2UP63
names: Similarity
messages: Belongs to the invertebrate defensin family.

510516:AO090026000141
gene id: 510516:AO090026000141
uniprot id: Q2UFN0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

510516:AO090011000503
gene id: 510516:AO090011000503
uniprot id: Q2U0B8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090005000495
gene id: 510516:AO090005000495
uniprot id: Q2USB4
names: Similarity
messages: Belongs to the CoA-transferase III family.

510516:AO090005000064
gene id: 510516:AO090005000064
uniprot id: Q2UTD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090020000387
gene id: 510516:AO090020000387
uniprot id: Q2U4D4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

510516:AO090009000395
gene id: 510516:AO090009000395
uniprot id: Q2UUA2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

510516:AO090001000304
gene id: 510516:AO090001000304
uniprot id: Q2UNM5
names: Function
names: Similarity
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.

510516:AO090023000574
gene id: 510516:AO090023000574
uniprot id: Q2UH58
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

510516:AO090012000956
gene id: 510516:AO090012000956
uniprot id: Q2UBL0
names: Similarity
messages: Belongs to the fructosamine kinase family.

510516:AO090020000537
gene id: 510516:AO090020000537
uniprot id: Q2U411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

510516:AO090012000468
gene id: 510516:AO090012000468
uniprot id: Q2UCS3
names: Similarity
messages: Belongs to the IST1 family.

510516:AO090012001014
gene id: 510516:AO090012001014
uniprot id: Q2UBG1
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000045
gene id: 510516:AO090011000045
uniprot id: Q2U1F8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000351
gene id: 510516:AO090011000351
uniprot id: Q2U0P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

510516:AO090701000193
gene id: 510516:AO090701000193
uniprot id: Q2U931
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

510516:AO090138000066
gene id: 510516:AO090138000066
uniprot id: Q2U1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Secreted

510516:AO090020000516
gene id: 510516:AO090020000516
uniprot id: Q2U429
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090038000038
gene id: 510516:AO090038000038
uniprot id: Q2U3H2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000766
gene id: 510516:AO090026000766
uniprot id: Q2UE45
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090003000724
gene id: 510516:AO090003000724
uniprot id: Q2UKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

510516:AO090003000104
gene id: 510516:AO090003000104
uniprot id: Q2UM80
names: Similarity
messages: Belongs to the GINS4/SLD5 family.

510516:AO090023000287
gene id: 510516:AO090023000287
uniprot id: Q2UHW4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000488
gene id: 510516:AO090010000488
uniprot id: Q2TWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090023000453
gene id: 510516:AO090023000453
uniprot id: Q2UHG7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000085
gene id: 510516:AO090020000085
uniprot id: Q2U540
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

510516:AO090023000692
gene id: 510516:AO090023000692
uniprot id: Q9C1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family.
messages: Catalyzes the hydrolysis of inorganic orthophosphate from phytate.
messages: Secreted

510516:AO090020000657
gene id: 510516:AO090020000657
uniprot id: Q2U3R0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000874
gene id: 510516:AO090023000874
uniprot id: Q2UGE4
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

510516:AO090023001000
gene id: 510516:AO090023001000
uniprot id: Q2UG30
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005000227
gene id: 510516:AO090005000227
uniprot id: Q2USZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

510516:AO090010000407
gene id: 510516:AO090010000407
uniprot id: Q2TWU8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000392
gene id: 510516:AO090026000392
uniprot id: Q2UF13
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

510516:AO090001000604
gene id: 510516:AO090001000604
uniprot id: Q2UMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Cell membrane
messages: Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan (By similarity).

510516:AO090012000189
gene id: 510516:AO090012000189
uniprot id: Q2UDF7
names: Similarity
messages: Belongs to the importin alpha family.

510516:AO090023000732
gene id: 510516:AO090023000732
uniprot id: Q2UGS2
names: Similarity
messages: Belongs to the peptidase M28 family.

510516:AO090038000282
gene id: 510516:AO090038000282
uniprot id: Q2U2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

510516:AO090010000484
gene id: 510516:AO090010000484
uniprot id: Q2TWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).
messages: Secreted

510516:AO090138000036
gene id: 510516:AO090138000036
uniprot id: Q2U1Z6
names: Function
names: Similarity
messages: Belongs to the choline monooxygenase family.
messages: Catalyzes the first step of the osmoprotectant glycine betaine synthesis.

510516:AO090026000425
gene id: 510516:AO090026000425
uniprot id: Q2UEY7
names: Similarity
messages: Belongs to the SIN1 family.

510516:AO090003000529
gene id: 510516:AO090003000529
uniprot id: Q2UL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

510516:AO090003001237
gene id: 510516:AO090003001237
uniprot id: Q2UJF6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000669
gene id: 510516:AO090023000669
uniprot id: Q2UGX8
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

510516:AO090003000789
gene id: 510516:AO090003000789
uniprot id: Q2UKI8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

510516:AO090003000034
gene id: 510516:AO090003000034
uniprot id: Q2UME2
names: Similarity
messages: Belongs to the chloroperoxidase family.

510516:AO090009000653
gene id: 510516:AO090009000653
uniprot id: Q5KU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity).

510516:AO090003000056
gene id: 510516:AO090003000056
uniprot id: Q2UMC3
names: Similarity
messages: Belongs to the AAA ATPase family.

510516:AO090012000715
gene id: 510516:AO090012000715
uniprot id: Q2UC70
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090009000638
gene id: 510516:AO090009000638
uniprot id: Q2UTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

510516:AO090138000031
gene id: 510516:AO090138000031
uniprot id: Q2U201
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000309
gene id: 510516:AO090020000309
uniprot id: Q2U4K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Prevacuolar compartment membrane
messages: Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) (By similarity).
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.

510516:AO090005000029
gene id: 510516:AO090005000029
uniprot id: P52956
names: Activity Regulation
names: Biotechnology
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:19810726, PubMed:15968570). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:19810726, PubMed:15968570).
messages: Competitively inhibited by the carboxylic acids butyric acid, valeric acid and hexanoic acid (PubMed:15968570). Competitively inhibited by the dicarboxylic acid succinic acid (PubMed:15968570). Competitively inhibited by the alcohols propan-1-ol, butan-1-ol, hexan-1-ol, octan-1-ol, and butane-1,4-diol (PubMed:15968570).
messages: Secreted
messages: This enzyme enables the fungus to utilize the biodegradable plastics poly(butylene succinate) (PBS) and poly(butylene succinate-co-butylene adipate) (PBSA) as sole carbon source and could therefore be used in plastic recycling.

510516:AO090026000469
gene id: 510516:AO090026000469
uniprot id: Q2UEV2
names: Similarity
messages: Belongs to the SAP30 family.

510516:AO090003000962
gene id: 510516:AO090003000962
uniprot id: Q06157
names: Function
names: Induction
names: Subcellular Location Annotation
messages: By omega amino acids.
messages: Nucleus
messages: Positively regulates the expression of genes involved in the catabolism of certain amides, omega amino acids, and lactams.

510516:AO090120000144
gene id: 510516:AO090120000144
uniprot id: Q2U6Q0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090003000927
gene id: 510516:AO090003000927
uniprot id: Q2UK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
messages: Cytoplasm
messages: Nucleus

510516:AO090701000729
gene id: 510516:AO090701000729
uniprot id: Q2U7R8
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

510516:AO090020000521
gene id: 510516:AO090020000521
uniprot id: Q877B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

510516:AO090012000155
gene id: 510516:AO090012000155
uniprot id: Q2UDJ0
names: Similarity
messages: Belongs to the PPP phosphatase family.

510516:AO090001000428
gene id: 510516:AO090001000428
uniprot id: Q2UNB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: Interacts with the SSU processome.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

510516:AO090001000698
gene id: 510516:AO090001000698
uniprot id: Q2UMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

510516:AO090003000285
gene id: 510516:AO090003000285
uniprot id: Q2ULS7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

510516:AO090026000022
gene id: 510516:AO090026000022
uniprot id: Q2UFZ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090701000032
gene id: 510516:AO090701000032
uniprot id: Q2U9H2
names: Similarity
messages: Belongs to the GET4 family.

510516:AO090001000751
gene id: 510516:AO090001000751
uniprot id: Q2UMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

510516:AO090120000109
gene id: 510516:AO090120000109
uniprot id: Q2U6T0
names: Similarity
messages: Belongs to the hexokinase family.

510516:AO090023000312
gene id: 510516:AO090023000312
uniprot id: Q2UHU1
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090701000014
gene id: 510516:AO090701000014
uniprot id: Q2U9I8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

510516:AO090103000051
gene id: 510516:AO090103000051
uniprot id: Q2TYY9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090005000693
gene id: 510516:AO090005000693
uniprot id: Q2URT8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000864
gene id: 510516:AO090012000864
uniprot id: Q2UBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

510516:AO090005000218
gene id: 510516:AO090005000218
uniprot id: Q2UT05
names: Similarity
messages: Belongs to the MNN1/MNT family.

510516:AO090003000679
gene id: 510516:AO090003000679
uniprot id: Q2UKT8
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

510516:AO090701000719
gene id: 510516:AO090701000719
uniprot id: Q2U7S6
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

510516:AO090001000449
gene id: 510516:AO090001000449
uniprot id: Q2UN98
names: Similarity
messages: Belongs to the neutral ceramidase family.

510516:AO090003001054
gene id: 510516:AO090003001054
uniprot id: Q2UJV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

510516:AO090009000443
gene id: 510516:AO090009000443
uniprot id: Q2UU61
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090701000408
gene id: 510516:AO090701000408
uniprot id: Q2U8J5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090009000173
gene id: 510516:AO090009000173
uniprot id: Q2UUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis.

510516:AO090701000299
gene id: 510516:AO090701000299
uniprot id: Q2U8T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

510516:AO090012000161
gene id: 510516:AO090012000161
uniprot id: Q2UDI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003000721
gene id: 510516:AO090003000721
uniprot id: Q2UKP9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

510516:AO090103000382
gene id: 510516:AO090103000382
uniprot id: Q2TY58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090010000261
gene id: 510516:AO090010000261
uniprot id: Q2TX70
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Homotetramer.

510516:AO090003000828
gene id: 510516:AO090003000828
uniprot id: Q2UKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

510516:AO090026000375
gene id: 510516:AO090026000375
uniprot id: Q2UF27
names: Similarity
messages: Belongs to the tannase family.

510516:AO090005001517
gene id: 510516:AO090005001517
uniprot id: Q2UPT5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

510516:AO090023000319
gene id: 510516:AO090023000319
uniprot id: Q2UHT5
names: Similarity
messages: Belongs to the HscB family.

510516:AO090701000167
gene id: 510516:AO090701000167
uniprot id: Q2U955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of egd2 and egd1. NAC associates with ribosomes via egd1 (By similarity).

510516:AO090103000130
gene id: 510516:AO090103000130
uniprot id: Q2TYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005001383
gene id: 510516:AO090005001383
uniprot id: Q2UQ57
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090005000682
gene id: 510516:AO090005000682
uniprot id: Q2URU9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

510516:AO090020000603
gene id: 510516:AO090020000603
uniprot id: Q2U3V4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: By D-xylose, L-arabinose or L-arabitol.
messages: Cytoplasm
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).

510516:AO090005000751
gene id: 510516:AO090005000751
uniprot id: Q2URN7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090012000136
gene id: 510516:AO090012000136
uniprot id: Q2UDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090102000568
gene id: 510516:AO090102000568
uniprot id: Q2UA29
names: Similarity
messages: Belongs to the COG2 family.

510516:AO090026000842
gene id: 510516:AO090026000842
uniprot id: Q2UDX6
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090012000757
gene id: 510516:AO090012000757
uniprot id: Q2UC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

510516:AO090102000011
gene id: 510516:AO090102000011
uniprot id: Q2UBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Pectinolytic enzyme involved in the degradation of xylogalacturonan (xga), a galacturonan backbone heavily substituted with xylose, and which is one important component of the hairy regions of pectin. Activity requires a galacturonic acid backbone substituted with xylose (By similarity).
messages: Secreted

510516:AO090005001506
gene id: 510516:AO090005001506
uniprot id: Q2UPU4
names: Similarity
messages: Belongs to the isochorismatase family.

510516:AO090012000451
gene id: 510516:AO090012000451
uniprot id: Q2UCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
messages: Secreted

510516:AO090012001016
gene id: 510516:AO090012001016
uniprot id: Q2UBF9
names: Similarity
messages: Belongs to the SELO family.

510516:AO090001000123
gene id: 510516:AO090001000123
uniprot id: Q2UP41
names: Subunit
messages: Homodimer.

510516:AO090005000931
gene id: 510516:AO090005000931
uniprot id: Q2UR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

510516:AO090023000611
gene id: 510516:AO090023000611
uniprot id: Q2UH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anthrone oxygenase family.
messages: Membrane

510516:AO090001000033
gene id: 510516:AO090001000033
uniprot id: Q2UPB9
names: Function
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Probable aminotransferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090120000344
gene id: 510516:AO090120000344
uniprot id: Q2U681
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

510516:AO090701000190
gene id: 510516:AO090701000190
uniprot id: Q2U934
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000465
gene id: 510516:AO090001000465
uniprot id: Q2UN85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090103000452
gene id: 510516:AO090103000452
uniprot id: Q2TXZ3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001514
gene id: 510516:AO090003001514
uniprot id: Q2UIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pectinesterase family.
messages: Involved in maceration and soft-rotting of plant tissue.
messages: Secreted

510516:AO090012000917
gene id: 510516:AO090012000917
uniprot id: Q2UBP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

510516:AO090102000620
gene id: 510516:AO090102000620
uniprot id: Q2U9Y1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

510516:AO090003000008
gene id: 510516:AO090003000008
uniprot id: Q2UMG7
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

510516:AO090026000037
gene id: 510516:AO090026000037
uniprot id: Q2UFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005000116
gene id: 510516:AO090005000116
uniprot id: Q2UT87
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

510516:AO090009000414
gene id: 510516:AO090009000414
uniprot id: Q2UU88
names: Similarity
messages: Belongs to the IlvD/Edd family.

510516:AO090026000135
gene id: 510516:AO090026000135
uniprot id: Q2UFN6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

510516:AO090011000596
gene id: 510516:AO090011000596
uniprot id: Q2U044
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

510516:AO090103000172
gene id: 510516:AO090103000172
uniprot id: Q2TYN9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

510516:AO090012000540
gene id: 510516:AO090012000540
uniprot id: Q2UCL4
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

510516:AO090011000331
gene id: 510516:AO090011000331
uniprot id: Q2U0R8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090103000327
gene id: 510516:AO090103000327
uniprot id: Q2TYA6
names: Similarity
messages: Belongs to the TTC4 family.

510516:AO090120000360
gene id: 510516:AO090120000360
uniprot id: Q2U667
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with ncs6 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

510516:AO090020000631
gene id: 510516:AO090020000631
uniprot id: Q2U3T0
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090701000046
gene id: 510516:AO090701000046
uniprot id: Q2U9F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090102000457
gene id: 510516:AO090102000457
uniprot id: Q2UAB9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090103000095
gene id: 510516:AO090103000095
uniprot id: Q2TYV4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000701
gene id: 510516:AO090020000701
uniprot id: Q2U3M1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090011000859
gene id: 510516:AO090011000859
uniprot id: Q2TZG7
names: Function
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

510516:AO090009000626
gene id: 510516:AO090009000626
uniprot id: Q2UTR4
names: Similarity
messages: Belongs to the ATG101 family.

510516:AO090009000239
gene id: 510516:AO090009000239
uniprot id: Q2UUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

510516:AO090005000852
gene id: 510516:AO090005000852
uniprot id: Q2URF3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000377
gene id: 510516:AO090001000377
uniprot id: Q2UNG4
names: Similarity
messages: Belongs to the peptidase M16 family.

510516:AO090011000793
gene id: 510516:AO090011000793
uniprot id: Q2TZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

510516:AO090005001044
gene id: 510516:AO090005001044
uniprot id: P10281
names: Miscellaneous
names: Similarity
messages: Belongs to the RNase T2 family.
messages: Preference for adenylic acid.

510516:AO090010000708
gene id: 510516:AO090010000708
uniprot id: Q2TW47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HIBADH-related family.
messages: Homodimer.
messages: NADPH-dependent reductive aminase that catalyzes the reductive coupling of a broad set of carbonyl compounds with a variety of primary and secondary amines (Ref.2). Possesses remarkably high activity for the reductive amination of ketones and amines, often with high stereoselectivity and in some cases with ketone:amine ratios as low as 1:1 (Ref.2). The cofactor NADPH, the carbonyl compound and the amine are added to the enzyme in that sequence, followed by the release of product, NADP(+) being released at last (Ref.2). RedAm is also able to act in the reverse, oxidative direction and exhibits activity in the dehydrogenation of amines to yield imines (Ref.2). The highest activity is found for 1-methyl-tetrahydroquinoline and acyclic amines are also found to be transformed (Ref.2).

510516:AO090023000577
gene id: 510516:AO090023000577
uniprot id: Q2UH56
names: Function
names: Similarity
messages: 2-hydroxyacid dehydrogenase that is capable to reduce pyruvate, hydroxypyruvate and glyoxylate in a NADPH- or NADH-dependent manner (PubMed:26615399). In contrast to 2-HadhD/morA, does not recognize 4-methyl-2-oxopentanoate (MOA) as a substrate (PubMed:26615399).
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

510516:AO090001000619
gene id: 510516:AO090001000619
uniprot id: Q2UMU6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090120000479
gene id: 510516:AO090120000479
uniprot id: Q2U5W9
names: Similarity
messages: Belongs to the PP2C family.

510516:AO090001000095
gene id: 510516:AO090001000095
uniprot id: Q2UP65
names: Similarity
messages: Belongs to the isochorismatase family.

510516:AO090003000690
gene id: 510516:AO090003000690
uniprot id: Q2UKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

510516:AO090011000238
gene id: 510516:AO090011000238
uniprot id: Q2U0Z3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090009000567
gene id: 510516:AO090009000567
uniprot id: Q2UTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Membrane

510516:AO090012000275
gene id: 510516:AO090012000275
uniprot id: Q2UD86
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

510516:AO090009000313
gene id: 510516:AO090009000313
uniprot id: Q2UUH4
names: Similarity
messages: Belongs to the calreticulin family.

510516:AO090120000053
gene id: 510516:AO090120000053
uniprot id: Q2U6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090005000457
gene id: 510516:AO090005000457
uniprot id: Q2USE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.
messages: Mitochondrion matrix

510516:AO090011000869
gene id: 510516:AO090011000869
uniprot id: Q2TZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090012000445
gene id: 510516:AO090012000445
uniprot id: Q2UCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 35 family.
messages: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
messages: Secreted

510516:AO090009000702
gene id: 510516:AO090009000702
uniprot id: Q2UTJ9
names: Similarity
messages: Belongs to the aspartokinase family.

510516:AO090023000334
gene id: 510516:AO090023000334
uniprot id: Q2UHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

510516:AO090001000749
gene id: 510516:AO090001000749
uniprot id: Q2UMH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity).
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090102000015
gene id: 510516:AO090102000015
uniprot id: Q2UBD4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

510516:AO090023000582
gene id: 510516:AO090023000582
uniprot id: Q2UH51
names: Function
messages: Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

510516:AO090023000258
gene id: 510516:AO090023000258
uniprot id: Q2UHY6
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

510516:AO090001000546
gene id: 510516:AO090001000546
uniprot id: Q2UN10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

510516:AO090003000948
gene id: 510516:AO090003000948
uniprot id: Q2UK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

510516:AO090005000625
gene id: 510516:AO090005000625
uniprot id: Q2URZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

510516:AO090003001177
gene id: 510516:AO090003001177
uniprot id: Q2UJK3
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

510516:AO090038000040
gene id: 510516:AO090038000040
uniprot id: Q2U3H0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

510516:AO090001000364
gene id: 510516:AO090001000364
uniprot id: Q2UNH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

510516:AO090010000108
gene id: 510516:AO090010000108
uniprot id: Q2TXK4
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

510516:AO090003000903
gene id: 510516:AO090003000903
uniprot id: Q2UK95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

510516:AO090009000573
gene id: 510516:AO090009000573
uniprot id: Q2UTV6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090701000076
gene id: 510516:AO090701000076
uniprot id: Q2U9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

510516:AO090026000820
gene id: 510516:AO090026000820
uniprot id: Q2UDZ5
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

510516:AO090026000677
gene id: 510516:AO090026000677
uniprot id: Q2UEC3
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

510516:AO090206000058
gene id: 510516:AO090206000058
uniprot id: Q2PIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.
messages: Belongs to the CWF11 family.
messages: Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
messages: Nucleus

510516:AO090102000570
gene id: 510516:AO090102000570
uniprot id: Q2UA27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of nbp35 and two labile, bridging clusters between subunits of the nbp35-cfd1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 nbp35 and 2 cfd1 chains.

510516:AO090701000038
gene id: 510516:AO090701000038
uniprot id: Q2U9G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

510516:AO090001000338
gene id: 510516:AO090001000338
uniprot id: Q2UNJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

510516:AO090026000730
gene id: 510516:AO090026000730
uniprot id: Q2UE79
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

510516:AO090005001084
gene id: 510516:AO090005001084
uniprot id: Q2UQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity).
messages: Secreted

510516:AO090102000265
gene id: 510516:AO090102000265
uniprot id: Q2UAS1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090124000015
gene id: 510516:AO090124000015
uniprot id: Q2U798
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

510516:AO090020000626
gene id: 510516:AO090020000626
uniprot id: Q2U3T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

510516:AO090120000448
gene id: 510516:AO090120000448
uniprot id: Q2U5Z1
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090124000027
gene id: 510516:AO090124000027
uniprot id: Q2U786
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

510516:AO090701000734
gene id: 510516:AO090701000734
uniprot id: Q2U7R4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG3 family.
messages: Cytoplasm
messages: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
messages: Monomer. Interacts with atg8 through an intermediate thioester bond through the C-terminal Gly of atg8. Also interacts with the 40 amino acid C-terminal region of the E1-like atg7 enzyme. Interacts also with the atg12-atg5 conjugate.
messages: The N-terminal region is involved in phosphatidylethanolamine-binding and is required for atg8-PE conjugation.
messages: The flexible region (FR) is required for atg7-binding.
messages: The handle region (HR) contains the atg8 interaction motif (AIM) and mediates binding to atg8. It is crucial for the cytoplasm-to-vacuole targeting pathway (By similarity).

510516:AO090012000375
gene id: 510516:AO090012000375
uniprot id: Q2UD01
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090001000094
gene id: 510516:AO090001000094
uniprot id: Q2UP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Mitochondrion
messages: Oligomer.

510516:AO090003001256
gene id: 510516:AO090003001256
uniprot id: Q2UJD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

510516:AO090003001309
gene id: 510516:AO090003001309
uniprot id: Q2UJ94
names: Similarity
messages: Belongs to the Gfa family.

510516:AO090120000416
gene id: 510516:AO090120000416
uniprot id: Q2U618
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

510516:AO090026000012
gene id: 510516:AO090026000012
uniprot id: Q2UG03
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

510516:AO090023000052
gene id: 510516:AO090023000052
uniprot id: Q2UIH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

510516:AO090011000913
gene id: 510516:AO090011000913
uniprot id: Q2TZC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090023000528
gene id: 510516:AO090023000528
uniprot id: Q2UH99
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090003000718
gene id: 510516:AO090003000718
uniprot id: Q2UKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

510516:AO090003000148
gene id: 510516:AO090003000148
uniprot id: Q2UM43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

510516:AO090005000405
gene id: 510516:AO090005000405
uniprot id: Q2USJ2
names: Cofactor
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cu(2+) or Zn(2+).
messages: Mitochondrion inner membrane
messages: Monomer.
messages: Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
messages: The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria.

510516:AO090120000284
gene id: 510516:AO090120000284
uniprot id: Q2U6D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PROPPIN family.
messages: Component of the PI(3,5)P2 regulatory complex.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway, for the recruitment of atg8 and atg16 to the PAS in nutrient-rich medium, and for its recruitment to and dissociation from the PAS under starvation conditions.
messages: The N-terminus might form a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.
messages: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).
messages: Vacuole membrane

510516:AO090020000558
gene id: 510516:AO090020000558
uniprot id: Q2U3Z3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090023000151
gene id: 510516:AO090023000151
uniprot id: Q2UI87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
messages: Secreted

510516:AO090011000778
gene id: 510516:AO090011000778
uniprot id: Q2TZP1
names: Similarity
messages: Belongs to the NEMF family.

510516:AO090026000548
gene id: 510516:AO090026000548
uniprot id: Q2UEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090103000074
gene id: 510516:AO090103000074
uniprot id: P78581
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the tannase family.
messages: Heterooctamer of 4 33 kDa and 4 30 kDa subunits linked by disulfide bond(s).
messages: Hydrolyzes ester bonds of tannic acid to produce gallic acid and glucose.
messages: The N-terminus of the 30 kDa subunit is blocked.
messages: The protein is glycosylated to a carbohydrate content of 22.7%.

510516:AO090120000238
gene id: 510516:AO090120000238
uniprot id: Q2U6H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

510516:AO090003001353
gene id: 510516:AO090003001353
uniprot id: Q2UJ53
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000313
gene id: 510516:AO090102000313
uniprot id: Q2UAN6
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090011000693
gene id: 510516:AO090011000693
uniprot id: Q2TZW5
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090023000263
gene id: 510516:AO090023000263
uniprot id: Q2UHY2
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

510516:AO090701000710
gene id: 510516:AO090701000710
uniprot id: Q2U7T3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000101
gene id: 510516:AO090102000101
uniprot id: Q2UB56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasm
messages: Membrane
messages: Required for vacuolar protein sorting.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.

510516:AO090038000386
gene id: 510516:AO090038000386
uniprot id: Q2U2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

510516:AO090023000245
gene id: 510516:AO090023000245
uniprot id: Q2UHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090023000192
gene id: 510516:AO090023000192
uniprot id: Q2UI50
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090009000275
gene id: 510516:AO090009000275
uniprot id: Q2UUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090001000127
gene id: 510516:AO090001000127
uniprot id: Q2UP37
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

510516:AO090005000146
gene id: 510516:AO090005000146
uniprot id: Q2UT59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

510516:AO090701000094
gene id: 510516:AO090701000094
uniprot id: Q2U9B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

510516:AO090011000588
gene id: 510516:AO090011000588
uniprot id: Q2U050
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

510516:AO090003001364
gene id: 510516:AO090003001364
uniprot id: Q2UJ43
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

510516:AO090701000209
gene id: 510516:AO090701000209
uniprot id: Q2U918
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

510516:AO090206000054
gene id: 510516:AO090206000054
uniprot id: Q2PIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Involved in chromosome segregation during meiosis and DNA damage repair.
messages: Nucleus

510516:AO090005000265
gene id: 510516:AO090005000265
uniprot id: Q2USW5
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

510516:AO090003000268
gene id: 510516:AO090003000268
uniprot id: Q2ULU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090138000018
gene id: 510516:AO090138000018
uniprot id: Q2U210
names: Function
names: Subcellular Location Annotation
messages: Cell wall formation.
messages: Cytoplasm

510516:AO090120000461
gene id: 510516:AO090120000461
uniprot id: Q2U5Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

510516:AO090009000575
gene id: 510516:AO090009000575
uniprot id: Q2UTV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090003000096
gene id: 510516:AO090003000096
uniprot id: Q2UM88
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

510516:AO090103000169
gene id: 510516:AO090103000169
uniprot id: Q2TYP1
names: Similarity
messages: Belongs to the lysine N-acyltransferase MbtK family.

510516:AO090113000085
gene id: 510516:AO090113000085
uniprot id: Q2U5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

510516:AO090009000651
gene id: 510516:AO090009000651
uniprot id: Q2UTP2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000426
gene id: 510516:AO090023000426
uniprot id: Q2UHJ2
names: Similarity
messages: Belongs to the TYW1 family.

510516:AO090001000151
gene id: 510516:AO090001000151
uniprot id: Q2UP15
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

510516:AO090003000611
gene id: 510516:AO090003000611
uniprot id: Q2UKZ2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

510516:AO090113000186
gene id: 510516:AO090113000186
uniprot id: Q2U5D7
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090005001175
gene id: 510516:AO090005001175
uniprot id: Q2UQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

510516:AO090011000118
gene id: 510516:AO090011000118
uniprot id: P00651
names: Similarity
names: Subunit
messages: Belongs to the ribonuclease N1/T1 family.
messages: Monomer.

510516:AO090003001197
gene id: 510516:AO090003001197
uniprot id: Q2UJI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
messages: Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.
messages: Nucleus
messages: cytosol

510516:AO090701000886
gene id: 510516:AO090701000886
uniprot id: Q2U7D1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090010000767
gene id: 510516:AO090010000767
uniprot id: Q2TVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

510516:AO090103000443
gene id: 510516:AO090103000443
uniprot id: Q2TY02
names: Similarity
messages: Belongs to the oxoprolinase family.

510516:AO090012000979
gene id: 510516:AO090012000979
uniprot id: Q2UBI9
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

510516:AO090005000615
gene id: 510516:AO090005000615
uniprot id: Q2US08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090001000031
gene id: 510516:AO090001000031
uniprot id: Q2UPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: MFS efflux transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).
messages: Membrane

510516:AO090011000599
gene id: 510516:AO090011000599
uniprot id: Q2U041
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090701000402
gene id: 510516:AO090701000402
uniprot id: Q2U8K1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000438
gene id: 510516:AO090005000438
uniprot id: Q2USG3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

510516:AO090003001064
gene id: 510516:AO090003001064
uniprot id: Q2UJU9
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

510516:AO090023000729
gene id: 510516:AO090023000729
uniprot id: Q2UGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.
messages: Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).
messages: Nucleus

510516:AO090003000124
gene id: 510516:AO090003000124
uniprot id: Q2UM63
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090103000331
gene id: 510516:AO090103000331
uniprot id: Q2TYA2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

510516:AO090012001025
gene id: 510516:AO090012001025
uniprot id: Q2UBF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M43B family.
messages: Secreted
messages: Secreted metalloproteinase that allows assimilation of proteinaceous substrates.

510516:AO090003000040
gene id: 510516:AO090003000040
uniprot id: Q2UMD7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000837
gene id: 510516:AO090023000837
uniprot id: Q2UGH7
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

510516:AO090003000453
gene id: 510516:AO090003000453
uniprot id: Q2ULD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

510516:AO090026000579
gene id: 510516:AO090026000579
uniprot id: Q2UEK7
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: Impairs the production of trihydroxy confertifolin and deacetyl astellolides A and B.
messages: Membrane

510516:AO090020000117
gene id: 510516:AO090020000117
uniprot id: Q2U515
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090023000363
gene id: 510516:AO090023000363
uniprot id: Q2UHP5
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090026000083
gene id: 510516:AO090026000083
uniprot id: Q8NK92
names: Activity Regulation
names: Cofactor
names: Developmental Stage
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Activity found in solid culture only. Increases at the initial growth stage and decreases in the late growth stage.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Inhibited by antipain and leupeptin.
messages: N-glycosylated.
messages: O-glycosylated.
messages: Serine endopeptidase which hydrolyzes a range of fluorogenic peptide substrates containing the basic residues arginine or lysine at the P1 position and prefers paired basic resides. Also hydrolyzes clupeine and salmine, activates plasminogen and converts trypsinogen to trypsin.
messages: extracellular space

510516:AO090003001231
gene id: 510516:AO090003001231
uniprot id: Q2UJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

510516:AO090003000147
gene id: 510516:AO090003000147
uniprot id: Q2UM44
names: Similarity
messages: Belongs to the SH3YL1 family.

510516:AO090026000063
gene id: 510516:AO090026000063
uniprot id: Q2UFV5
names: Similarity
messages: Belongs to the chloroperoxidase family.

510516:AO090103000087
gene id: 510516:AO090103000087
uniprot id: Q2TYW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

510516:AO090120000132
gene id: 510516:AO090120000132
uniprot id: Q2U6Q9
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

510516:AO090701000130
gene id: 510516:AO090701000130
uniprot id: Q2U987
names: Similarity
messages: Belongs to the COG1 family.

510516:AO090010000429
gene id: 510516:AO090010000429
uniprot id: Q2TWT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090102000115
gene id: 510516:AO090102000115
uniprot id: Q2UB44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

510516:AO090003000210
gene id: 510516:AO090003000210
uniprot id: Q2ULZ3
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

510516:AO090001000549
gene id: 510516:AO090001000549
uniprot id: Q2UN07
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090020000297
gene id: 510516:AO090020000297
uniprot id: Q2U4L0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

510516:AO090102000122
gene id: 510516:AO090102000122
uniprot id: Q2UB39
names: Similarity
messages: Belongs to the CAF1 family.

510516:AO090003000586
gene id: 510516:AO090003000586
uniprot id: Q2UL15
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

510516:AO090012000410
gene id: 510516:AO090012000410
uniprot id: Q2UCX4
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

510516:AO090001000339
gene id: 510516:AO090001000339
uniprot id: Q2UNJ5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

510516:AO090026000636
gene id: 510516:AO090026000636
uniprot id: Q2UEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EFG1 family.
messages: Involved in rRNA processing.
messages: nucleolus

510516:AO090012000220
gene id: 510516:AO090012000220
uniprot id: Q2UDD1
names: Similarity
messages: Belongs to the glutamine synthetase family.

510516:AO090701000481
gene id: 510516:AO090701000481
uniprot id: Q2U8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 43 family.
messages: Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
messages: Secreted

510516:AO090005001358
gene id: 510516:AO090005001358
uniprot id: Q2UQ80
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090003000002
gene id: 510516:AO090003000002
uniprot id: Q2UMH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

510516:AO090003000055
gene id: 510516:AO090003000055
uniprot id: Q12560
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+) is required for catalysis and for stabilizing the dimer.

510516:AO090003001525
gene id: 510516:AO090003001525
uniprot id: Q2UIQ3
names: Similarity
messages: Belongs to the amidase family.

510516:AO090003001115
gene id: 510516:AO090003001115
uniprot id: Q2UJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

510516:AO090103000159
gene id: 510516:AO090103000159
uniprot id: Q2TYP9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000374
gene id: 510516:AO090011000374
uniprot id: Q2U0M8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090012000427
gene id: 510516:AO090012000427
uniprot id: Q2UCW0
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

510516:AO090009000436
gene id: 510516:AO090009000436
uniprot id: Q2UU67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
messages: Mitochondrion inner membrane

510516:AO090003001252
gene id: 510516:AO090003001252
uniprot id: Q2UJE3
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090026000314
gene id: 510516:AO090026000314
uniprot id: Q2UF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

510516:AO090011000508
gene id: 510516:AO090011000508
uniprot id: Q2U0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

510516:AO090009000477
gene id: 510516:AO090009000477
uniprot id: Q2UU34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIMR family. LMBRD1 subfamily.
messages: Lysosome membrane
messages: Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors.

510516:AO090026000549
gene id: 510516:AO090026000549
uniprot id: Q2UEN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex which is a heterotetramer of sld5, psf1, psf2 and psf3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity).

510516:AO090010000126
gene id: 510516:AO090010000126
uniprot id: Q2TXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090011000851
gene id: 510516:AO090011000851
uniprot id: Q2TZH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
messages: Chromosome
messages: Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.
messages: Nucleus

510516:AO090026000265
gene id: 510516:AO090026000265
uniprot id: Q2UFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

510516:AO090005000108
gene id: 510516:AO090005000108
uniprot id: Q2UT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090003000547
gene id: 510516:AO090003000547
uniprot id: Q2UL51
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090102000560
gene id: 510516:AO090102000560
uniprot id: Q2UA36
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001377
gene id: 510516:AO090003001377
uniprot id: Q2UJ30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090001000710
gene id: 510516:AO090001000710
uniprot id: Q2UML5
names: Similarity
messages: Belongs to the hexokinase family.

510516:AO090012000680
gene id: 510516:AO090012000680
uniprot id: Q2UCA1
names: Function
names: Similarity
messages: Belongs to the lysophospholipase family.
messages: Catalyzes the release of fatty acids from lysophospholipids.

510516:AO090026000701
gene id: 510516:AO090026000701
uniprot id: Q2UEA3
names: Similarity
messages: Belongs to the PPP phosphatase family.

510516:AO090023000988
gene id: 510516:AO090023000988
uniprot id: Q2UG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090010000198
gene id: 510516:AO090010000198
uniprot id: Q2TXC7
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090120000102
gene id: 510516:AO090120000102
uniprot id: Q2U6T7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000863
gene id: 510516:AO090023000863
uniprot id: Q2UGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090124000018
gene id: 510516:AO090124000018
uniprot id: Q2U795
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

510516:AO090124000019
gene id: 510516:AO090124000019
uniprot id: Q2U794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

510516:AO090003000180
gene id: 510516:AO090003000180
uniprot id: Q2UM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

510516:AO090003000873
gene id: 510516:AO090003000873
uniprot id: Q2UKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: May mediate the reduction of outer membrane cytochrome b5.
messages: Mitochondrion outer membrane

510516:AO090011000775
gene id: 510516:AO090011000775
uniprot id: Q2TZP4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

510516:AO090009000588
gene id: 510516:AO090009000588
uniprot id: Q2UTU6
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090005001380
gene id: 510516:AO090005001380
uniprot id: Q2UQ60
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

510516:AO090023000038
gene id: 510516:AO090023000038
uniprot id: Q2UII9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

510516:AO090026000747
gene id: 510516:AO090026000747
uniprot id: Q2UE64
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090011000832
gene id: 510516:AO090011000832
uniprot id: Q2TZJ2
names: Similarity
messages: Belongs to the NSRP1 family.

510516:AO090103000459
gene id: 510516:AO090103000459
uniprot id: Q2TXY8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

510516:AO090023000271
gene id: 510516:AO090023000271
uniprot id: Q2UHX5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000352
gene id: 510516:AO090120000352
uniprot id: Q2U674
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

510516:AO090023000242
gene id: 510516:AO090023000242
uniprot id: Q2UI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

510516:AO090113000136
gene id: 510516:AO090113000136
uniprot id: Q2U5I0
names: Biotechnology
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family.
messages: Expression is controlled by the kojic acid gene cluster transcription factor kojR (PubMed:21514215). Expression is also positively regulated by the secondary metabolism general regulator laeA (PubMed:21897021). Expression is negatively regulated by the transcription factor kpeA (PubMed:30790620). Finally, nitrogen deficiency increases the expression (PubMed:26657710).
messages: Kojic acid can be used for several biotechnological applications, including use as an antibiotic, as an additive to prevent browning of food materials, and as an antioxidant (PubMed:17119644). Kojic acid is also interesting as an inhibitor of tyrosinase (PubMed:7714722). Finally, kojic acid has also been shown to have strong nematicidal activity (PubMed:27197670).
messages: Leads to the loss of kojic acid production.
messages: Probable FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent (PubMed:20849972, PubMed:35034313). Glucose might be converted to kojic acid by a combination of dehydrogenase and dehydratase reactions involving kojA and probably additional enzymes (PubMed:20849972).

510516:AO090005001646
gene id: 510516:AO090005001646
uniprot id: Q2UPH0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

510516:AO090005000754
gene id: 510516:AO090005000754
uniprot id: Q2URN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

510516:AO090003001474
gene id: 510516:AO090003001474
uniprot id: Q2UIU5
names: Similarity
messages: Belongs to the isochorismatase family.

510516:AO090138000061
gene id: 510516:AO090138000061
uniprot id: Q2U1X2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

510516:AO090005000720
gene id: 510516:AO090005000720
uniprot id: Q2URR3
names: Similarity
messages: Belongs to the Mo25 family.

510516:AO090011000572
gene id: 510516:AO090011000572
uniprot id: Q2U062
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090005000528
gene id: 510516:AO090005000528
uniprot id: Q2US86
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

510516:AO090038000567
gene id: 510516:AO090038000567
uniprot id: Q2U280
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000782
gene id: 510516:AO090011000782
uniprot id: Q2TZN8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

510516:AO090103000333
gene id: 510516:AO090103000333
uniprot id: Q2TYA0
names: Similarity
messages: Belongs to the SDO1/SBDS family.

510516:AO090102000026
gene id: 510516:AO090102000026
uniprot id: Q2UBC5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090166000099
gene id: 510516:AO090166000099
uniprot id: Q2U9L8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090001000136
gene id: 510516:AO090001000136
uniprot id: Q2UP29
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090701000024
gene id: 510516:AO090701000024
uniprot id: Q2U9H9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

510516:AO090102000594
gene id: 510516:AO090102000594
uniprot id: Q2UA04
names: Similarity
messages: Belongs to the RRP15 family.

510516:AO090023000653
gene id: 510516:AO090023000653
uniprot id: Q2UGZ2
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

510516:AO090701000018
gene id: 510516:AO090701000018
uniprot id: Q2U9I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090206000038
gene id: 510516:AO090206000038
uniprot id: Q2PIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

510516:AO090001000395
gene id: 510516:AO090001000395
uniprot id: Q2UNE8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000309
gene id: 510516:AO090010000309
uniprot id: Q2TX31
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090005001077
gene id: 510516:AO090005001077
uniprot id: Q2UQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

510516:AO090001000051
gene id: 510516:AO090001000051
uniprot id: Q2UPA1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090026000120
gene id: 510516:AO090026000120
uniprot id: Q2UFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Secreted

510516:AO090038000357
gene id: 510516:AO090038000357
uniprot id: Q2U2Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

510516:AO090023000297
gene id: 510516:AO090023000297
uniprot id: Q2UHV4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

510516:AO090701000451
gene id: 510516:AO090701000451
uniprot id: Q2U8F4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

510516:AO090003001024
gene id: 510516:AO090003001024
uniprot id: Q2UJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM54 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
messages: Mitochondrion inner membrane

510516:AO090010000119
gene id: 510516:AO090010000119
uniprot id: Q2TXJ4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001455
gene id: 510516:AO090005001455
uniprot id: Q2UPY9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000525
gene id: 510516:AO090001000525
uniprot id: Q2UN31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
messages: Mitochondrion matrix

510516:AO090010000519
gene id: 510516:AO090010000519
uniprot id: Q2TWK7
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

510516:AO090701000720
gene id: 510516:AO090701000720
uniprot id: Q2U7S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.

510516:AO090011000789
gene id: 510516:AO090011000789
uniprot id: Q2TZN1
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005000316
gene id: 510516:AO090005000316
uniprot id: Q2USS0
names: Similarity
messages: Belongs to the amidase family.

510516:AO090102000499
gene id: 510516:AO090102000499
uniprot id: Q2UA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

510516:AO090011000577
gene id: 510516:AO090011000577
uniprot id: Q2U058
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

510516:AO090010000005
gene id: 510516:AO090010000005
uniprot id: Q2TXU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090102000388
gene id: 510516:AO090102000388
uniprot id: Q2UAH1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001372
gene id: 510516:AO090005001372
uniprot id: Q2UQ67
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090003001112
gene id: 510516:AO090003001112
uniprot id: Q2UJR1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

510516:AO090003000842
gene id: 510516:AO090003000842
uniprot id: Q877B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex and sar1.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity).

510516:AO090020000497
gene id: 510516:AO090020000497
uniprot id: Q2U446
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090038000498
gene id: 510516:AO090038000498
uniprot id: Q2U2D3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090113000088
gene id: 510516:AO090113000088
uniprot id: Q2U5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005001090
gene id: 510516:AO090005001090
uniprot id: Q2UQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 16 family.
messages: Cell membrane
messages: Membrane

510516:AO090005001642
gene id: 510516:AO090005001642
uniprot id: Q2UPH3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

510516:AO090012000745
gene id: 510516:AO090012000745
uniprot id: Q2UC46
names: Function
messages: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.

510516:AO090001000693
gene id: 510516:AO090001000693
uniprot id: Q2UMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

510516:AO090010000773
gene id: 510516:AO090010000773
uniprot id: Q2TVY3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

510516:AO090001000737
gene id: 510516:AO090001000737
uniprot id: Q2UMI9
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090038000092
gene id: 510516:AO090038000092
uniprot id: Q2U3C8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

510516:AO090113000147
gene id: 510516:AO090113000147
uniprot id: Q2U5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090009000469
gene id: 510516:AO090009000469
uniprot id: Q2UU42
names: Similarity
messages: Belongs to the FMO family.

510516:AO090701000858
gene id: 510516:AO090701000858
uniprot id: Q2U7F7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000607
gene id: 510516:AO090020000607
uniprot id: Q2U3V1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000014
gene id: 510516:AO090010000014
uniprot id: Q2TXT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

510516:AO090038000597
gene id: 510516:AO090038000597
uniprot id: Q2U253
names: Similarity
messages: Belongs to the RRP7 family.

510516:AO090010000603
gene id: 510516:AO090010000603
uniprot id: Q2TWD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090003000081
gene id: 510516:AO090003000081
uniprot id: Q2UMA1
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

510516:AO090020000536
gene id: 510516:AO090020000536
uniprot id: Q2U412
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090023000191
gene id: 510516:AO090023000191
uniprot id: Q2UI51
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000326
gene id: 510516:AO090005000326
uniprot id: Q2USR2
names: Subcellular Location Annotation
messages: Secreted

510516:AO090009000362
gene id: 510516:AO090009000362
uniprot id: Q2UUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

510516:AO090003000057
gene id: 510516:AO090003000057
uniprot id: Q2UMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 47 family.
messages: Cytoplasmic vesicle lumen
messages: Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
messages: Monomer.

510516:AO090012000660
gene id: 510516:AO090012000660
uniprot id: Q2UCB7
names: Function
names: Similarity
messages: Belongs to the peptidase C14B family.
messages: Involved in cell death (apoptosis).

510516:AO090003000884
gene id: 510516:AO090003000884
uniprot id: Q2UKB1
names: Similarity
messages: Belongs to the NPR2 family.

510516:AO090701000124
gene id: 510516:AO090701000124
uniprot id: Q2U992
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

510516:AO090206000022
gene id: 510516:AO090206000022
uniprot id: Q2PIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

510516:AO090701000389
gene id: 510516:AO090701000389
uniprot id: Q2U8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis.

510516:AO090138000028
gene id: 510516:AO090138000028
uniprot id: Q2U203
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090005000759
gene id: 510516:AO090005000759
uniprot id: Q2URN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

510516:AO090026000791
gene id: 510516:AO090026000791
uniprot id: Q2UE21
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

510516:AO090120000212
gene id: 510516:AO090120000212
uniprot id: Q2U6J3
names: Similarity
messages: Belongs to the RNase PH family.

510516:AO090012000006
gene id: 510516:AO090012000006
uniprot id: Q2UDW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

510516:AO090005000987
gene id: 510516:AO090005000987
uniprot id: Q2UR37
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000018
gene id: 510516:AO090010000018
uniprot id: Q2TXT6
names: Similarity
messages: Belongs to the aegerolysin family.

510516:AO090023000585
gene id: 510516:AO090023000585
uniprot id: Q2UH48
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000879
gene id: 510516:AO090011000879
uniprot id: Q2TZE8
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

510516:AO090102000021
gene id: 510516:AO090102000021
uniprot id: Q2UBC9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000572
gene id: 510516:AO090020000572
uniprot id: Q2U3Y1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000057
gene id: 510516:AO090026000057
uniprot id: Q2UFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090003000476
gene id: 510516:AO090003000476
uniprot id: Q2ULB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 47 family.
messages: Ca(2+). Can also use Mg(2+), but with lower efficiency.
messages: Cytoplasmic vesicle lumen
messages: Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
messages: Monomer.

510516:AO090005000083
gene id: 510516:AO090005000083
uniprot id: Q2UTB6
names: Similarity
messages: Belongs to the hexokinase family.

510516:AO090003001503
gene id: 510516:AO090003001503
uniprot id: Q2UIS1
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

510516:AO090011000297
gene id: 510516:AO090011000297
uniprot id: Q2U0U8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090023000485
gene id: 510516:AO090023000485
uniprot id: Q2UHD9
names: Similarity
messages: Belongs to the synaptobrevin family.

510516:AO090023000488
gene id: 510516:AO090023000488
uniprot id: Q2UHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090103000406
gene id: 510516:AO090103000406
uniprot id: Q2TY36
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090026000391
gene id: 510516:AO090026000391
uniprot id: Q2UF14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

510516:AO090003001391
gene id: 510516:AO090003001391
uniprot id: Q2UJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090009000031
gene id: 510516:AO090009000031
uniprot id: Q2UV62
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090003001247
gene id: 510516:AO090003001247
uniprot id: Q2UJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

510516:AO090120000403
gene id: 510516:AO090120000403
uniprot id: Q2U630
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

510516:AO090010000735
gene id: 510516:AO090010000735
uniprot id: Q2TW21
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000014
gene id: 510516:AO090011000014
uniprot id: Q2U1I7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000213
gene id: 510516:AO090011000213
uniprot id: Q2U113
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090001000358
gene id: 510516:AO090001000358
uniprot id: Q2UNI0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

510516:AO090012000929
gene id: 510516:AO090012000929
uniprot id: Q2UBN5
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

510516:AO090023000862
gene id: 510516:AO090023000862
uniprot id: Q2UGF4
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

510516:AO090023000147
gene id: 510516:AO090023000147
uniprot id: Q2UI90
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

510516:AO090003000849
gene id: 510516:AO090003000849
uniprot id: Q2UKD8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

510516:AO090038000111
gene id: 510516:AO090038000111
uniprot id: Q2U3B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M35 family.
messages: Binds 1 zinc ion per subunit.
messages: Secreted
messages: Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine.

510516:AO090026000231
gene id: 510516:AO090026000231
uniprot id: Q2UFF2
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090102000008
gene id: 510516:AO090102000008
uniprot id: Q2UBE1
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090005000479
gene id: 510516:AO090005000479
uniprot id: Q2USC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

510516:AO090026000323
gene id: 510516:AO090026000323
uniprot id: Q2UF71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

510516:AO090001000734
gene id: 510516:AO090001000734
uniprot id: Q2UMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
messages: Vacuole membrane

510516:AO090005001424
gene id: 510516:AO090005001424
uniprot id: Q2UQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

510516:AO090009000697
gene id: 510516:AO090009000697
uniprot id: Q2UTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

510516:AO090113000105
gene id: 510516:AO090113000105
uniprot id: Q2U5K7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

510516:AO090026000091
gene id: 510516:AO090026000091
uniprot id: Q2UFS7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000493
gene id: 510516:AO090005000493
uniprot id: Q2USB6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090124000061
gene id: 510516:AO090124000061
uniprot id: Q2U755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Membrane

510516:AO090701000328
gene id: 510516:AO090701000328
uniprot id: Q2U8R0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001008
gene id: 510516:AO090005001008
uniprot id: Q2UR20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

510516:AO090023000744
gene id: 510516:AO090023000744
uniprot id: Q2UGR5
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

510516:AO090003000244
gene id: 510516:AO090003000244
uniprot id: Q2ULW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

510516:AO090011000626
gene id: 510516:AO090011000626
uniprot id: Q2U017
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.

510516:AO090003000282
gene id: 510516:AO090003000282
uniprot id: Q2ULT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

510516:AO090113000029
gene id: 510516:AO090113000029
uniprot id: Q2U5S4
names: Function
messages: Gamma-glutamyltransferase.

510516:AO090003001178
gene id: 510516:AO090003001178
uniprot id: Q2UJK2
names: Similarity
messages: Belongs to the RMD1/sif2 family.

510516:AO090005001529
gene id: 510516:AO090005001529
uniprot id: Q2UPS4
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090038000631
gene id: 510516:AO090038000631
uniprot id: Q86ZV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090005001257
gene id: 510516:AO090005001257
uniprot id: Q2UQG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090102000148
gene id: 510516:AO090102000148
uniprot id: Q2UB18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090020000676
gene id: 510516:AO090020000676
uniprot id: Q2U3P5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090023000315
gene id: 510516:AO090023000315
uniprot id: Q2UHT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

510516:AO090005000668
gene id: 510516:AO090005000668
uniprot id: Q2URW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

510516:AO090005000103
gene id: 510516:AO090005000103
uniprot id: Q2UT98
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090038000414
gene id: 510516:AO090038000414
uniprot id: Q2U2L1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000798
gene id: 510516:AO090023000798
uniprot id: Q2UGL4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

510516:AO090003000746
gene id: 510516:AO090003000746
uniprot id: P57749
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible interconversion of glucose 1-phosphate and glucose 6-phosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose.
messages: Cytoplasm

510516:AO090005001590
gene id: 510516:AO090005001590
uniprot id: Q2UPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090009000296
gene id: 510516:AO090009000296
uniprot id: Q2UUJ0
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

510516:AO090009000700
gene id: 510516:AO090009000700
uniprot id: Q2UTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

510516:AO090026000140
gene id: 510516:AO090026000140
uniprot id: Q2UFN1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090003000061
gene id: 510516:AO090003000061
uniprot id: Q2UMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090138000204
gene id: 510516:AO090138000204
uniprot id: Q2U1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

510516:AO090026000494
gene id: 510516:AO090026000494
uniprot id: Q2UET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090701000554
gene id: 510516:AO090701000554
uniprot id: Q2U863
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

510516:AO090003000804
gene id: 510516:AO090003000804
uniprot id: Q2UKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit trm8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

510516:AO090005001427
gene id: 510516:AO090005001427
uniprot id: Q2UQ13
names: Function
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

510516:AO090011000889
gene id: 510516:AO090011000889
uniprot id: Q2TZE1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090009000465
gene id: 510516:AO090009000465
uniprot id: Q2UU45
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090020000164
gene id: 510516:AO090020000164
uniprot id: Q2U4X4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

510516:AO090102000640
gene id: 510516:AO090102000640
uniprot id: Q2U9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

510516:AO090701000070
gene id: 510516:AO090701000070
uniprot id: Q2U9D6
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

510516:AO090003000943
gene id: 510516:AO090003000943
uniprot id: Q2UK58
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

510516:AO090701000115
gene id: 510516:AO090701000115
uniprot id: Q2U9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

510516:AO090009000634
gene id: 510516:AO090009000634
uniprot id: Q2UTQ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090003001359
gene id: 510516:AO090003001359
uniprot id: Q2UJ48
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

510516:AO090003000606
gene id: 510516:AO090003000606
uniprot id: Q2UKZ7
names: Similarity
messages: Belongs to the TFIIB family.

510516:AO090012000971
gene id: 510516:AO090012000971
uniprot id: Q2UBJ7
names: Similarity
messages: Belongs to the RNase H family.

510516:AO090103000278
gene id: 510516:AO090103000278
uniprot id: Q2TYE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090113000178
gene id: 510516:AO090113000178
uniprot id: Q2U5E5
names: Similarity
messages: Belongs to the Necrosis inducing protein (NPP1) family.

510516:AO090012000175
gene id: 510516:AO090012000175
uniprot id: Q2UDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

510516:AO090005001640
gene id: 510516:AO090005001640
uniprot id: Q2UPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.
messages: Nucleus
messages: kinetochore

510516:AO090005001083
gene id: 510516:AO090005001083
uniprot id: Q2UQV8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

510516:AO090038000264
gene id: 510516:AO090038000264
uniprot id: Q2U2Y9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Integral membrane transporter that imports quinic acid to be catabolized as a carbon source.
messages: Interacts with creB.
messages: Ubiquitinated. Deubiquitinated by creB, probably to control its activity or amount.

510516:AO090005001620
gene id: 510516:AO090005001620
uniprot id: Q2UPJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

510516:AO090026000356
gene id: 510516:AO090026000356
uniprot id: Q2UF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

510516:AO090012000717
gene id: 510516:AO090012000717
uniprot id: Q2UC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

510516:AO090010000035
gene id: 510516:AO090010000035
uniprot id: Q2TXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090103000338
gene id: 510516:AO090103000338
uniprot id: Q2TY95
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

510516:AO090012001026
gene id: 510516:AO090012001026
uniprot id: Q2UBE9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

510516:AO090701000756
gene id: 510516:AO090701000756
uniprot id: Q2U7P5
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090038000624
gene id: 510516:AO090038000624
uniprot id: Q2U230
names: Similarity
messages: Belongs to the OSBP family.

510516:AO090138000037
gene id: 510516:AO090138000037
uniprot id: Q2U1Z5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000940
gene id: 510516:AO090005000940
uniprot id: Q2UR74
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000672
gene id: 510516:AO090010000672
uniprot id: Q2TW77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090012000394
gene id: 510516:AO090012000394
uniprot id: Q2UCY8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090012000193
gene id: 510516:AO090012000193
uniprot id: Q2UDF5
names: Similarity
messages: Belongs to the UreD family.

510516:AO090005001346
gene id: 510516:AO090005001346
uniprot id: Q2UQ91
names: Similarity
messages: Belongs to the TBCC family.

510516:AO090701000282
gene id: 510516:AO090701000282
uniprot id: Q2U8V1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090038000229
gene id: 510516:AO090038000229
uniprot id: Q2U319
names: Similarity
messages: Belongs to the peptidase A1 family.

510516:AO090120000404
gene id: 510516:AO090120000404
uniprot id: Q2U629
names: Similarity
messages: Belongs to the NAD kinase family.

510516:AO090001000577
gene id: 510516:AO090001000577
uniprot id: Q2UMX9
names: Similarity
messages: Belongs to the Luc7 family.

510516:AO090009000123
gene id: 510516:AO090009000123
uniprot id: Q2UUY5
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Homotetramer.

510516:AO090102000477
gene id: 510516:AO090102000477
uniprot id: Q2UAA4
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090026000830
gene id: 510516:AO090026000830
uniprot id: Q2UDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

510516:AO090020000493
gene id: 510516:AO090020000493
uniprot id: Q2U450
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

510516:AO090012000551
gene id: 510516:AO090012000551
uniprot id: Q2UCK3
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

510516:AO090003000356
gene id: 510516:AO090003000356
uniprot id: Q2ULM1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

510516:AO090020000635
gene id: 510516:AO090020000635
uniprot id: Q2U3S7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090020000436
gene id: 510516:AO090020000436
uniprot id: Q2U492
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: Cell membrane
messages: Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan (By similarity).

510516:AO090026000650
gene id: 510516:AO090026000650
uniprot id: Q2UEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090103000232
gene id: 510516:AO090103000232
uniprot id: Q2TYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

510516:AO090023000795
gene id: 510516:AO090023000795
uniprot id: Q2UGL7
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090103000026
gene id: 510516:AO090103000026
uniprot id: Q2TZ11
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090120000098
gene id: 510516:AO090120000098
uniprot id: Q2U6U1
names: Similarity
messages: Belongs to the Rab GDI family.

510516:AO090010000358
gene id: 510516:AO090010000358
uniprot id: Q2TWY7
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090026000530
gene id: 510516:AO090026000530
uniprot id: Q2UEQ0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000492
gene id: 510516:AO090026000492
uniprot id: Q2UET3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

510516:AO090023000226
gene id: 510516:AO090023000226
uniprot id: Q2UI17
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

510516:AO090011000415
gene id: 510516:AO090011000415
uniprot id: Q2U0J6
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Abolishes the production of heptelidic acid.
messages: Belongs to the cytochrome P450 family.
messages: Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing.
messages: Membrane

510516:AO090012000841
gene id: 510516:AO090012000841
uniprot id: Q2UBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
messages: Nucleus

510516:AO090003000879
gene id: 510516:AO090003000879
uniprot id: Q2UKB4
names: Cofactor
names: PTM
names: Similarity
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.

510516:AO090023000951
gene id: 510516:AO090023000951
uniprot id: Q2UG74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

510516:AO090120000273
gene id: 510516:AO090120000273
uniprot id: Q2U6E2
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

510516:AO090003000602
gene id: 510516:AO090003000602
uniprot id: Q2UL01
names: Subcellular Location Annotation
messages: Membrane

510516:AO090009000196
gene id: 510516:AO090009000196
uniprot id: Q2UUS5
names: Subcellular Location Annotation
messages: Mitochondrion

510516:AO090023000646
gene id: 510516:AO090023000646
uniprot id: Q2UGZ8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000129
gene id: 510516:AO090701000129
uniprot id: Q2U988
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

510516:AO090012000489
gene id: 510516:AO090012000489
uniprot id: Q2UCQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090010000399
gene id: 510516:AO090010000399
uniprot id: Q2TWV6
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

510516:AO090138000044
gene id: 510516:AO090138000044
uniprot id: Q2U1Y8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

510516:AO090009000284
gene id: 510516:AO090009000284
uniprot id: Q2UUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.

510516:AO090023000671
gene id: 510516:AO090023000671
uniprot id: Q2UGX6
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

510516:AO090023000809
gene id: 510516:AO090023000809
uniprot id: Q2UGK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

510516:AO090005001594
gene id: 510516:AO090005001594
uniprot id: Q2UPL6
names: Similarity
messages: Belongs to the cytidylyltransferase family.

510516:AO090003000920
gene id: 510516:AO090003000920
uniprot id: Q2UK79
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000328
gene id: 510516:AO090001000328
uniprot id: Q2UNK4
names: Similarity
messages: Belongs to the IF-3 family.

510516:AO090012000441
gene id: 510516:AO090012000441
uniprot id: Q2UCU7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000480
gene id: 510516:AO090102000480
uniprot id: Q2UAA1
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

510516:AO090023000153
gene id: 510516:AO090023000153
uniprot id: Q2UI86
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090206000047
gene id: 510516:AO090206000047
uniprot id: Q2PIV5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

510516:AO090003001142
gene id: 510516:AO090003001142
uniprot id: Q2UJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

510516:AO090023000793
gene id: 510516:AO090023000793
uniprot id: Q2UGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

510516:AO090701000647
gene id: 510516:AO090701000647
uniprot id: Q2U7Y7
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090026000676
gene id: 510516:AO090026000676
uniprot id: Q2UEC4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

510516:AO090023001003
gene id: 510516:AO090023001003
uniprot id: Q2UG27
names: Similarity
messages: Belongs to the cytidylyltransferase family.

510516:AO090020000468
gene id: 510516:AO090020000468
uniprot id: Q2U468
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

510516:AO090012000797
gene id: 510516:AO090012000797
uniprot id: Q2UC03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

510516:AO090001000458
gene id: 510516:AO090001000458
uniprot id: Q2UN90
names: Similarity
messages: Belongs to the SURF6 family.

510516:AO090026000257
gene id: 510516:AO090026000257
uniprot id: Q2UFC7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090011000798
gene id: 510516:AO090011000798
uniprot id: Q2TZM2
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

510516:AO090009000424
gene id: 510516:AO090009000424
uniprot id: Q2UU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

510516:AO090003000589
gene id: 510516:AO090003000589
uniprot id: Q2UL12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

510516:AO090003000582
gene id: 510516:AO090003000582
uniprot id: Q2UL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

510516:AO090026000394
gene id: 510516:AO090026000394
uniprot id: Q2UF11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

510516:AO090038000131
gene id: 510516:AO090038000131
uniprot id: Q2U395
names: Subcellular Location Annotation
messages: Secreted

510516:AO090012000340
gene id: 510516:AO090012000340
uniprot id: Q2UD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

510516:AO090001000415
gene id: 510516:AO090001000415
uniprot id: Q2UND0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000519
gene id: 510516:AO090001000519
uniprot id: Q2UN37
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
messages: Binds to histones H3 and H4.
messages: Inhibited by both FK506 and rapamycin.
messages: Nucleus
messages: PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression.

510516:AO090120000386
gene id: 510516:AO090120000386
uniprot id: Q2U645
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

510516:AO090001000332
gene id: 510516:AO090001000332
uniprot id: Q2UNK1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

510516:AO090005000775
gene id: 510516:AO090005000775
uniprot id: Q2URL9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090138000040
gene id: 510516:AO090138000040
uniprot id: Q2U1Z2
names: Similarity
messages: Belongs to the MSOX/MTOX family.

510516:AO090012000274
gene id: 510516:AO090012000274
uniprot id: Q2UD87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

510516:AO090026000726
gene id: 510516:AO090026000726
uniprot id: Q2UE83
names: Subcellular Location Annotation
messages: Cell membrane

510516:AO090102000578
gene id: 510516:AO090102000578
uniprot id: Q2UA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

510516:AO090102000317
gene id: 510516:AO090102000317
uniprot id: Q2UAN3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000484
gene id: 510516:AO090120000484
uniprot id: Q2U5W4
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

510516:AO090003000411
gene id: 510516:AO090003000411
uniprot id: Q2ULH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by nfs1 and other mitochondrial proteins (By similarity). Hydrolyzes ATP (By similarity). Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).

510516:AO090026000703
gene id: 510516:AO090026000703
uniprot id: Q2UEA1
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

510516:AO090003000569
gene id: 510516:AO090003000569
uniprot id: Q2UL31
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

510516:AO090020000679
gene id: 510516:AO090020000679
uniprot id: Q2U3P3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000807
gene id: 510516:AO090026000807
uniprot id: Q2UE07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

510516:AO090023000303
gene id: 510516:AO090023000303
uniprot id: Q2UHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

510516:AO090011000449
gene id: 510516:AO090011000449
uniprot id: Q2U0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

510516:AO090009000715
gene id: 510516:AO090009000715
uniprot id: Q2UTI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

510516:AO090005000927
gene id: 510516:AO090005000927
uniprot id: Q2UR85
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

510516:AO090012000940
gene id: 510516:AO090012000940
uniprot id: Q2UBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: nucleolus

510516:AO090003001350
gene id: 510516:AO090003001350
uniprot id: Q2UJ55
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

510516:AO090701000225
gene id: 510516:AO090701000225
uniprot id: Q2U903
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

510516:AO090020000351
gene id: 510516:AO090020000351
uniprot id: Q2U4G6
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090001000110
gene id: 510516:AO090001000110
uniprot id: Q2UP52
names: Similarity
messages: Belongs to the thioredoxin family.

510516:AO090010000168
gene id: 510516:AO090010000168
uniprot id: Q2TXF3
names: Cofactor
names: Function
names: Similarity
messages: Alpha-ketoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).
messages: Belongs to the TfdA dioxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

510516:AO090003000044
gene id: 510516:AO090003000044
uniprot id: Q2UMD3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000764
gene id: 510516:AO090011000764
uniprot id: Q2TZQ3
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

510516:AO090026000270
gene id: 510516:AO090026000270
uniprot id: Q2UFB5
names: Similarity
messages: Belongs to the RNase PH family.

510516:AO090005000761
gene id: 510516:AO090005000761
uniprot id: Q2URM8
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

510516:AO090003000520
gene id: 510516:AO090003000520
uniprot id: Q2UL76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090003000364
gene id: 510516:AO090003000364
uniprot id: Q2ULL4
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

510516:AO090038000544
gene id: 510516:AO090038000544
uniprot id: Q2U2A0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090026000193
gene id: 510516:AO090026000193
uniprot id: Q2UFI6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001556
gene id: 510516:AO090003001556
uniprot id: Q2UIM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090009000701
gene id: 510516:AO090009000701
uniprot id: Q2UTK0
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090120000176
gene id: 510516:AO090120000176
uniprot id: Q2U6M4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000321
gene id: 510516:AO090026000321
uniprot id: Q2UF72
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

510516:AO090003000759
gene id: 510516:AO090003000759
uniprot id: Q2UKL5
names: Subcellular Location Annotation
messages: Cell membrane

510516:AO090120000232
gene id: 510516:AO090120000232
uniprot id: Q2U6H7
names: Similarity
messages: Belongs to the peptidase S10 family.

510516:AO090012000818
gene id: 510516:AO090012000818
uniprot id: Q2UBY2
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003000816
gene id: 510516:AO090003000816
uniprot id: Q2UKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

510516:AO090020000367
gene id: 510516:AO090020000367
uniprot id: Q2U4F3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000636
gene id: 510516:AO090102000636
uniprot id: Q2U9W7
names: Similarity
messages: Belongs to the WD repeat LST8 family.

510516:AO090020000623
gene id: 510516:AO090020000623
uniprot id: Q2U3T7
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

510516:AO090011000504
gene id: 510516:AO090011000504
uniprot id: Q2U0B7
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

510516:AO090103000328
gene id: 510516:AO090103000328
uniprot id: Q2TYA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

510516:AO090003000536
gene id: 510516:AO090003000536
uniprot id: Q2UL62
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003001141
gene id: 510516:AO090003001141
uniprot id: Q2UJN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

510516:AO090026000444
gene id: 510516:AO090026000444
uniprot id: Q2UEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least hat1 and hat2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

510516:AO090701000097
gene id: 510516:AO090701000097
uniprot id: Q2U9B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least bud32, cgi121, gon7, kae1 and pcc1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

510516:AO090009000055
gene id: 510516:AO090009000055
uniprot id: Q2UV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

510516:AO090003000038
gene id: 510516:AO090003000038
uniprot id: Q2UMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

510516:AO090001000216
gene id: 510516:AO090001000216
uniprot id: Q2UNV6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090011000653
gene id: 510516:AO090011000653
uniprot id: Q2TZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090113000006
gene id: 510516:AO090113000006
uniprot id: Q2U5U2
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

510516:AO090001000574
gene id: 510516:AO090001000574
uniprot id: Q2UMY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

510516:AO090003001393
gene id: 510516:AO090003001393
uniprot id: Q2UJ14
names: Similarity
messages: Belongs to the PrpF family.

510516:AO090003001498
gene id: 510516:AO090003001498
uniprot id: Q2UIS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

510516:AO090120000493
gene id: 510516:AO090120000493
uniprot id: Q9HGY8
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

510516:AO090005001206
gene id: 510516:AO090005001206
uniprot id: Q2UQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

510516:AO090003000545
gene id: 510516:AO090003000545
uniprot id: Q2UL53
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

510516:AO090012000588
gene id: 510516:AO090012000588
uniprot id: Q2UCH3
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090001000194
gene id: 510516:AO090001000194
uniprot id: Q2UNX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus
messages: Putative transcription factor.

510516:AO090010000524
gene id: 510516:AO090010000524
uniprot id: Q2TWK3
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090012000923
gene id: 510516:AO090012000923
uniprot id: Q2UBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RSP5/NEDD4 family.
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.
messages: Interacts with creD.

510516:AO090003000004
gene id: 510516:AO090003000004
uniprot id: Q2UMH1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

510516:AO090023000432
gene id: 510516:AO090023000432
uniprot id: Q2UHI6
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

510516:AO090001000101
gene id: 510516:AO090001000101
uniprot id: Q2UP60
names: Similarity
messages: Belongs to the phosphohexose mutase family.

510516:AO090003001222
gene id: 510516:AO090003001222
uniprot id: Q2UJH0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000332
gene id: 510516:AO090010000332
uniprot id: Q2TX10
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000390
gene id: 510516:AO090020000390
uniprot id: Q2U4D1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090026000369
gene id: 510516:AO090026000369
uniprot id: Q2UF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

510516:AO090005001360
gene id: 510516:AO090005001360
uniprot id: Q2UQ78
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

510516:AO090102000584
gene id: 510516:AO090102000584
uniprot id: Q2UA13
names: Similarity
messages: Belongs to the CoA-transferase III family.

510516:AO090023000824
gene id: 510516:AO090023000824
uniprot id: Q2UGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

510516:AO090009000674
gene id: 510516:AO090009000674
uniprot id: Q2UTM4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

510516:AO090023000465
gene id: 510516:AO090023000465
uniprot id: Q2UHF7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000425
gene id: 510516:AO090011000425
uniprot id: Q2U0I6
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090012000174
gene id: 510516:AO090012000174
uniprot id: Q2UDH1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000323
gene id: 510516:AO090001000323
uniprot id: Q2UNK9
names: Similarity
messages: Belongs to the tpcK family.

510516:AO090012000886
gene id: 510516:AO090012000886
uniprot id: Q2UBS4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090005001477
gene id: 510516:AO090005001477
uniprot id: Q2UPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

510516:AO090010000342
gene id: 510516:AO090010000342
uniprot id: Q2TX01
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090003000769
gene id: 510516:AO090003000769
uniprot id: Q2UKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Membrane

510516:AO090005001447
gene id: 510516:AO090005001447
uniprot id: Q2UPZ7
names: Activity Regulation
names: Cofactor
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Inhibited by zinc. Stimulated by calcium and bacitracin.
messages: Tetrahedron-shaped homododecamer built from six homodimers.
messages: The N-terminus is blocked.

510516:AO090001000485
gene id: 510516:AO090001000485
uniprot id: Q2UN68
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.

510516:AO090026000443
gene id: 510516:AO090026000443
uniprot id: Q2UEX2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

510516:AO090020000650
gene id: 510516:AO090020000650
uniprot id: Q2U3R5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090701000344
gene id: 510516:AO090701000344
uniprot id: Q2U8P6
names: Similarity
messages: Belongs to the NUP family.

510516:AO090166000064
gene id: 510516:AO090166000064
uniprot id: Q2U9Q0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000384
gene id: 510516:AO090003000384
uniprot id: Q2ULJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

510516:AO090010000333
gene id: 510516:AO090010000333
uniprot id: Q2TX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

510516:AO090701000290
gene id: 510516:AO090701000290
uniprot id: Q2U8U4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000455
gene id: 510516:AO090011000455
uniprot id: Q2U0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

510516:AO090005001065
gene id: 510516:AO090005001065
uniprot id: Q2UQX3
names: Similarity
messages: Belongs to the thioredoxin family.

510516:AO090005001275
gene id: 510516:AO090005001275
uniprot id: Q2UQF2
names: Similarity
messages: Belongs to the UTP6 family.

510516:AO090020000492
gene id: 510516:AO090020000492
uniprot id: Q2U451
names: Similarity
messages: Belongs to the AccD/PCCB family.

510516:AO090003001170
gene id: 510516:AO090003001170
uniprot id: Q2UJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

510516:AO090005001344
gene id: 510516:AO090005001344
uniprot id: Q2UQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 16 family.
messages: Cell membrane
messages: Membrane

510516:AO090026000524
gene id: 510516:AO090026000524
uniprot id: Q2UEQ5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

510516:AO090001000037
gene id: 510516:AO090001000037
uniprot id: Q2UPB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Thioredoxin reductase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).

510516:AO090026000585
gene id: 510516:AO090026000585
uniprot id: Q2UEK2
names: Disruption Phenotype
names: Domain
names: Function
names: Induction
names: Similarity
messages: Belongs to the NRP synthetase family.
messages: Expression is regulated by the secondary metabolite regulator cclA.
messages: Impairs the production of deacetyl astellolides A and B and leads to the accumulation of trihydroxy confertifolin.
messages: NRP synthetases are composed of discrete domains (adenylation (A), thiolation (T) or peptidyl carrier protein (PCP) and condensation (C) domains) which when grouped together are referred to as a single module. Each module is responsible for the recognition (via the A domain) and incorporation of a single amino acid into the growing peptide product. Thus, an NRP synthetase is generally composed of one or more modules and can terminate in a thioesterase domain (TE) that releases the newly synthesized peptide from the enzyme. Occasionally, epimerase (E) domains (responsible for L- to D- amino acid conversion) are present within the NRP synthetase. AsrA has the following single module architecture: A-T-C.
messages: Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).

510516:AO090701000324
gene id: 510516:AO090701000324
uniprot id: Q2U8R4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

510516:AO090003001348
gene id: 510516:AO090003001348
uniprot id: Q2UJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

510516:AO090023000256
gene id: 510516:AO090023000256
uniprot id: Q2UHY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

510516:AO090103000195
gene id: 510516:AO090103000195
uniprot id: Q2TYL8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090023000288
gene id: 510516:AO090023000288
uniprot id: Q2UHW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

510516:AO090166000048
gene id: 510516:AO090166000048
uniprot id: Q2U9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
messages: Secreted

510516:AO090001000417
gene id: 510516:AO090001000417
uniprot id: Q2UNC8
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

510516:AO090003000417
gene id: 510516:AO090003000417
uniprot id: Q2ULG8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

510516:AO090009000215
gene id: 510516:AO090009000215
uniprot id: Q2UUQ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

510516:AO090026000510
gene id: 510516:AO090026000510
uniprot id: Q2UER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

510516:AO090010000156
gene id: 510516:AO090010000156
uniprot id: Q2TXG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthase beta subunit; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

510516:AO090701000612
gene id: 510516:AO090701000612
uniprot id: Q2U813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

510516:AO090001000636
gene id: 510516:AO090001000636
uniprot id: Q2UMT0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000438
gene id: 510516:AO090003000438
uniprot id: Q2ULE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

510516:AO090011000295
gene id: 510516:AO090011000295
uniprot id: Q2U0V0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090026000329
gene id: 510516:AO090026000329
uniprot id: Q2UF66
names: Similarity
messages: Belongs to the RCAN family.

510516:AO090038000411
gene id: 510516:AO090038000411
uniprot id: Q2U2L4
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.

510516:AO090120000279
gene id: 510516:AO090120000279
uniprot id: Q2U6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 16 family.
messages: Cell membrane
messages: Membrane

510516:AO090010000007
gene id: 510516:AO090010000007
uniprot id: Q2TXU6
names: Similarity
messages: Belongs to the isochorismatase family.
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

510516:AO090020000212
gene id: 510516:AO090020000212
uniprot id: Q2U4T4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090003000363
gene id: 510516:AO090003000363
uniprot id: Q2ULL5
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090102000353
gene id: 510516:AO090102000353
uniprot id: Q2UAK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090010000034
gene id: 510516:AO090010000034
uniprot id: Q2TXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
messages: Secreted

510516:AO090001000543
gene id: 510516:AO090001000543
uniprot id: Q2UN13
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000749
gene id: 510516:AO090012000749
uniprot id: Q2UC42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pectinesterase family.
messages: Involved in maceration and soft-rotting of plant tissue.
messages: Secreted

510516:AO090020000192
gene id: 510516:AO090020000192
uniprot id: Q2U4V2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000221
gene id: 510516:AO090010000221
uniprot id: Q2TXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

510516:AO090010000406
gene id: 510516:AO090010000406
uniprot id: Q2TWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090001000599
gene id: 510516:AO090001000599
uniprot id: Q2UMW0
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

510516:AO090003000534
gene id: 510516:AO090003000534
uniprot id: Q2UL64
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

510516:AO090009000377
gene id: 510516:AO090009000377
uniprot id: Q2UUB9
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

510516:AO090005000114
gene id: 510516:AO090005000114
uniprot id: Q2UT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

510516:AO090001000325
gene id: 510516:AO090001000325
uniprot id: Q2UNK7
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

510516:AO090020000396
gene id: 510516:AO090020000396
uniprot id: Q2U4C6
names: Similarity
messages: Belongs to the CIA30 family.

510516:AO090012000629
gene id: 510516:AO090012000629
uniprot id: Q2UCE1
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

510516:AO090005001400
gene id: 510516:AO090005001400
uniprot id: Q2UQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Secreted
messages: Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.

510516:AO090020000183
gene id: 510516:AO090020000183
uniprot id: Q2U4V9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090005000806
gene id: 510516:AO090005000806
uniprot id: Q2URJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
messages: Heterodimer of an alpha and a beta subunit.
messages: Nucleus
messages: cytoskeleton

510516:AO090012000063
gene id: 510516:AO090012000063
uniprot id: Q2UDR6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000536
gene id: 510516:AO090102000536
uniprot id: Q2UA56
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

510516:AO090010000563
gene id: 510516:AO090010000563
uniprot id: Q2TWG8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

510516:AO090020000385
gene id: 510516:AO090020000385
uniprot id: Q2U4D6
names: Function
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
messages: Nitrilase that hydrolyzes preferentially phenylacetonitrile, (R,S)-mandelonitrile, and 3-indolylacetonitrile.

510516:AO090103000141
gene id: 510516:AO090103000141
uniprot id: Q2TYR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.
messages: Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
messages: Secreted

510516:AO090038000259
gene id: 510516:AO090038000259
uniprot id: Q2U2Z4
names: Similarity
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.

510516:AO090026000603
gene id: 510516:AO090026000603
uniprot id: Q2UEI6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

510516:AO090011000320
gene id: 510516:AO090011000320
uniprot id: Q2U0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity).

510516:AO090103000407
gene id: 510516:AO090103000407
uniprot id: Q2TY35
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090026000531
gene id: 510516:AO090026000531
uniprot id: Q2UEP9
names: Similarity
messages: Belongs to the CDC73 family.

510516:AO090010000706
gene id: 510516:AO090010000706
uniprot id: Q2TW49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).
messages: Secreted

510516:AO090023000032
gene id: 510516:AO090023000032
uniprot id: Q2UIJ5
names: Similarity
messages: Belongs to the aegerolysin family.

510516:AO090103000343
gene id: 510516:AO090103000343
uniprot id: Q2TY90
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090113000098
gene id: 510516:AO090113000098
uniprot id: Q2U5L4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090102000507
gene id: 510516:AO090102000507
uniprot id: Q2UA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

510516:AO090011000272
gene id: 510516:AO090011000272
uniprot id: Q2U0W7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Homotetramer.

510516:AO090010000224
gene id: 510516:AO090010000224
uniprot id: Q2TXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
messages: Mitochondrion inner membrane

510516:AO090020000418
gene id: 510516:AO090020000418
uniprot id: Q2U4A8
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

510516:AO090701000403
gene id: 510516:AO090701000403
uniprot id: Q2U8K0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

510516:AO090001000234
gene id: 510516:AO090001000234
uniprot id: Q2UNT9
names: Subcellular Location Annotation
messages: cytosol

510516:AO090026000611
gene id: 510516:AO090026000611
uniprot id: Q2UEI0
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

510516:AO090009000430
gene id: 510516:AO090009000430
uniprot id: Q2UU72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with trm82.
messages: Nucleus

510516:AO090003000058
gene id: 510516:AO090003000058
uniprot id: Q2UMC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Secreted

510516:AO090020000373
gene id: 510516:AO090020000373
uniprot id: Q2U4E7
names: Similarity
messages: Belongs to the amidase family.

510516:AO090003000750
gene id: 510516:AO090003000750
uniprot id: Q2UKM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.
messages: Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.
messages: Component of the SCF(sconB) E3 ubiquitin ligase complex.

510516:AO090012000248
gene id: 510516:AO090012000248
uniprot id: Q2UDA8
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

510516:AO090011000820
gene id: 510516:AO090011000820
uniprot id: Q2TZK3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000296
gene id: 510516:AO090012000296
uniprot id: Q2UD68
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001407
gene id: 510516:AO090005001407
uniprot id: Q2UQ33
names: Function
names: Similarity
messages: Belongs to the MBF1 family.
messages: Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.

510516:AO090005001472
gene id: 510516:AO090005001472
uniprot id: Q2UPX3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090026000317
gene id: 510516:AO090026000317
uniprot id: Q2UF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

510516:AO090005000037
gene id: 510516:AO090005000037
uniprot id: Q2UTF7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090026000771
gene id: 510516:AO090026000771
uniprot id: Q2UE40
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

510516:AO090001000712
gene id: 510516:AO090001000712
uniprot id: Q2UML3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

510516:AO090003000904
gene id: 510516:AO090003000904
uniprot id: Q2UK94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

510516:AO090102000255
gene id: 510516:AO090102000255
uniprot id: Q2UAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090026000115
gene id: 510516:AO090026000115
uniprot id: Q2UFQ6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090120000408
gene id: 510516:AO090120000408
uniprot id: Q2U626
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

510516:AO090038000139
gene id: 510516:AO090038000139
uniprot id: Q2U387
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Homotetramer.

510516:AO090003000367
gene id: 510516:AO090003000367
uniprot id: Q2ULL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090124000087
gene id: 510516:AO090124000087
uniprot id: Q2U730
names: Similarity
messages: Belongs to the HGH1 family.

510516:AO090003001062
gene id: 510516:AO090003001062
uniprot id: Q2UJV1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

510516:AO090003001067
gene id: 510516:AO090003001067
uniprot id: Q2UJU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

510516:AO090102000476
gene id: 510516:AO090102000476
uniprot id: Q2UAA5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000100
gene id: 510516:AO090120000100
uniprot id: Q2U6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

510516:AO090020000489
gene id: 510516:AO090020000489
uniprot id: Q2U454
names: Similarity
messages: Belongs to the PET191 family.

510516:AO090009000169
gene id: 510516:AO090009000169
uniprot id: Q2UUU8
names: Similarity
messages: Belongs to the MOG1 family.

510516:AO090011000416
gene id: 510516:AO090011000416
uniprot id: Q2U0J5
names: Disruption Phenotype
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Reduces markedly the expression of hepA and abolishes the production of heptelidic acid.
messages: Transcription factor; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing (PubMed:30466366). Both hepR and hepS regulate the transcription of the heptelidic acid cluster, but they are not involved in mutual transcriptional regulation and act with different mechanisms (PubMed:30466366).

510516:AO090023000641
gene id: 510516:AO090023000641
uniprot id: Q2UH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

510516:AO090009000050
gene id: 510516:AO090009000050
uniprot id: Q2UV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

510516:AO090005000266
gene id: 510516:AO090005000266
uniprot id: Q2USW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

510516:AO090701000041
gene id: 510516:AO090701000041
uniprot id: Q2U9G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

510516:AO090026000760
gene id: 510516:AO090026000760
uniprot id: Q2UE51
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000995
gene id: 510516:AO090003000995
uniprot id: Q2UK11
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

510516:AO090010000464
gene id: 510516:AO090010000464
uniprot id: Q2TWQ6
names: Similarity
messages: Belongs to the PAT1 family.

510516:AO090012000065
gene id: 510516:AO090012000065
uniprot id: Q2UDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090012000459
gene id: 510516:AO090012000459
uniprot id: Q2UCT1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

510516:AO090010000015
gene id: 510516:AO090010000015
uniprot id: Q2TXT8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003000196
gene id: 510516:AO090003000196
uniprot id: Q2UM03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

510516:AO090010000487
gene id: 510516:AO090010000487
uniprot id: Q2TWN5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

510516:AO090012000941
gene id: 510516:AO090012000941
uniprot id: Q2UBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.
messages: Secreted
messages: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.

510516:AO090012000732
gene id: 510516:AO090012000732
uniprot id: Q2UC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090003000309
gene id: 510516:AO090003000309
uniprot id: Q2ULQ7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090012000328
gene id: 510516:AO090012000328
uniprot id: Q2UD41
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Does not significantly affect miconazole susceptibility.
messages: Expression is slightly up-regulated in the presence of miconazole.
messages: Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility.

510516:AO090003000758
gene id: 510516:AO090003000758
uniprot id: Q9HFB3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH.
messages: Belongs to the pacC/RIM101 family.
messages: Binds to DNA. Interacts with palA, which binds to the two YPX[LI] motifs and is required for proteolytic processing (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity).

510516:AO090010000427
gene id: 510516:AO090010000427
uniprot id: Q2TWT6
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

510516:AO090026000008
gene id: 510516:AO090026000008
uniprot id: Q2UG07
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003001248
gene id: 510516:AO090003001248
uniprot id: Q2UJE7
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

510516:AO090701000140
gene id: 510516:AO090701000140
uniprot id: Q2U977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090038000162
gene id: 510516:AO090038000162
uniprot id: Q2U368
names: Subcellular Location Annotation
messages: Membrane

510516:AO090011000846
gene id: 510516:AO090011000846
uniprot id: Q2TZH9
names: Subcellular Location Annotation
messages: nuclear pore complex

510516:AO090005001182
gene id: 510516:AO090005001182
uniprot id: Q2UQM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

510516:AO090001000215
gene id: 510516:AO090001000215
uniprot id: Q2UNV7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000029
gene id: 510516:AO090701000029
uniprot id: Q2U9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090012000808
gene id: 510516:AO090012000808
uniprot id: Q2UBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

510516:AO090009000070
gene id: 510516:AO090009000070
uniprot id: Q2UV29
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

510516:AO090011000468
gene id: 510516:AO090011000468
uniprot id: Q2U0E7
names: Similarity
messages: Belongs to the CWC22 family.

510516:AO090003001386
gene id: 510516:AO090003001386
uniprot id: Q2UJ21
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000304
gene id: 510516:AO090120000304
uniprot id: Q2U6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090009000033
gene id: 510516:AO090009000033
uniprot id: Q2UV60
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

510516:AO090701000586
gene id: 510516:AO090701000586
uniprot id: Q2U836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

510516:AO090010000012
gene id: 510516:AO090010000012
uniprot id: Q2TXU1
names: Similarity
messages: Belongs to the proline racemase family.

510516:AO090010000626
gene id: 510516:AO090010000626
uniprot id: Q2TWB7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000829
gene id: 510516:AO090026000829
uniprot id: Q2UDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

510516:AO090120000046
gene id: 510516:AO090120000046
uniprot id: Q2U6Y2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

510516:AO090701000026
gene id: 510516:AO090701000026
uniprot id: Q2U9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

510516:AO090026000084
gene id: 510516:AO090026000084
uniprot id: Q2UFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090023000070
gene id: 510516:AO090023000070
uniprot id: Q2UIF9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

510516:AO090010000087
gene id: 510516:AO090010000087
uniprot id: Q2TXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
messages: Secreted

510516:AO090003000009
gene id: 510516:AO090003000009
uniprot id: Q2UMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090005001245
gene id: 510516:AO090005001245
uniprot id: Q2UQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

510516:AO090012000018
gene id: 510516:AO090012000018
uniprot id: Q2UDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090102000126
gene id: 510516:AO090102000126
uniprot id: Q2UB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

510516:AO090010000771
gene id: 510516:AO090010000771
uniprot id: Q2TVY5
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

510516:AO090012000284
gene id: 510516:AO090012000284
uniprot id: Q2UD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090038000309
gene id: 510516:AO090038000309
uniprot id: Q2U2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

510516:AO090003000460
gene id: 510516:AO090003000460
uniprot id: Q2ULC8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000706
gene id: 510516:AO090020000706
uniprot id: Q2U3L6
names: Function
names: Similarity
messages: Belongs to the peptidase S9A family.
messages: Belongs to the peptidase S9C family.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

510516:AO090005000845
gene id: 510516:AO090005000845
uniprot id: Q2URF8
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

510516:AO090012000235
gene id: 510516:AO090012000235
uniprot id: Q2UDB8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

510516:AO090701000473
gene id: 510516:AO090701000473
uniprot id: Q2U8D2
names: Function
names: Similarity
messages: Belongs to the lysophospholipase family.
messages: Catalyzes the release of fatty acids from lysophospholipids.

510516:AO090001000322
gene id: 510516:AO090001000322
uniprot id: Q2UNL0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

510516:AO090011000220
gene id: 510516:AO090011000220
uniprot id: Q2U108
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

510516:AO090011000550
gene id: 510516:AO090011000550
uniprot id: Q2U081
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

510516:AO090009000166
gene id: 510516:AO090009000166
uniprot id: Q2UUV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

510516:AO090701000631
gene id: 510516:AO090701000631
uniprot id: Q2U7Z7
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

510516:AO090012000801
gene id: 510516:AO090012000801
uniprot id: Q2UBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with rps21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

510516:AO090011000807
gene id: 510516:AO090011000807
uniprot id: Q2TZL3
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

510516:AO090005000129
gene id: 510516:AO090005000129
uniprot id: Q2UT75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

510516:AO090020000383
gene id: 510516:AO090020000383
uniprot id: Q2U4D8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090038000223
gene id: 510516:AO090038000223
uniprot id: Q2U325
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
messages: Secreted

510516:AO090166000076
gene id: 510516:AO090166000076
uniprot id: Q2U9N8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Homotetramer.

510516:AO090005000750
gene id: 510516:AO090005000750
uniprot id: Q2URN8
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

510516:AO090701000739
gene id: 510516:AO090701000739
uniprot id: Q2U7Q9
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

510516:AO090005000339
gene id: 510516:AO090005000339
uniprot id: Q2USQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090102000167
gene id: 510516:AO090102000167
uniprot id: Q2UAZ9
names: Disruption Phenotype
names: Function
messages: 4'-hydroxy-3'-methoxypropiophenone carrier protein; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554). The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554). Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554). During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable). O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable). Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable). PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).
messages: Decreases the production of 2,4'-dihydroxy-3'-methoxypropiophenone and but leads to the accumulation of 4'-hydroxy-3'-methoxypropiophenone.

510516:AO090020000209
gene id: 510516:AO090020000209
uniprot id: Q2U4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090012000494
gene id: 510516:AO090012000494
uniprot id: Q2UCQ1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000360
gene id: 510516:AO090102000360
uniprot id: Q2UAJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

510516:AO090005000377
gene id: 510516:AO090005000377
uniprot id: Q2USL8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

510516:AO090038000283
gene id: 510516:AO090038000283
uniprot id: Q2U2X3
names: Similarity
messages: Belongs to the RNR ribonuclease family.

510516:AO090026000423
gene id: 510516:AO090026000423
uniprot id: Q2UEY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

510516:AO090003000135
gene id: 510516:AO090003000135
uniprot id: Q2UM54
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

510516:AO090010000546
gene id: 510516:AO090010000546
uniprot id: Q2TWI2
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003000301
gene id: 510516:AO090003000301
uniprot id: Q2ULR3
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090701000606
gene id: 510516:AO090701000606
uniprot id: Q2U818
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

510516:AO090011000293
gene id: 510516:AO090011000293
uniprot id: Q2U0V2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000375
gene id: 510516:AO090020000375
uniprot id: Q2U4E5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090011000286
gene id: 510516:AO090011000286
uniprot id: Q2U0V9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090023000633
gene id: 510516:AO090023000633
uniprot id: Q2UH11
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

510516:AO090026000189
gene id: 510516:AO090026000189
uniprot id: Q76MU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

510516:AO090113000138
gene id: 510516:AO090113000138
uniprot id: Q2U5H8
names: Biotechnology
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Expression is controlled by the kojic acid gene cluster transcription factor kojR (PubMed:21514215). Expression is also positively regulated by the secondary metabolism general regulator laeA (PubMed:21897021). Finally, nitrogen deficiency also positively regulates expression (PubMed:26657710).
messages: Kojic acid can be used for several biotechnological applications, including use as an antibiotic, as an additive to prevent browning of food materials, and as an antioxidant (PubMed:17119644). Kojic acid is also interesting as an inhibitor of tyrosinase (PubMed:7714722). Finally, kojic acid has also been shown to have strong nematicidal activity (PubMed:27197670).
messages: MFS-type transporter; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent (PubMed:20849972, PubMed:35034313). Involved in the seretion of kojic acid (PubMed:20849972).
messages: Reduces secretion of kojic acid.

510516:AO090003000010
gene id: 510516:AO090003000010
uniprot id: Q2UMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

510516:AO090038000110
gene id: 510516:AO090038000110
uniprot id: Q2U3B3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

510516:AO090005000704
gene id: 510516:AO090005000704
uniprot id: Q2URS8
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090005001583
gene id: 510516:AO090005001583
uniprot id: Q2UPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

510516:AO090005000035
gene id: 510516:AO090005000035
uniprot id: Q2UTF9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

510516:AO090138000051
gene id: 510516:AO090138000051
uniprot id: Q2U1Y1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

510516:AO090026000731
gene id: 510516:AO090026000731
uniprot id: Q2UE78
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

510516:AO090005001073
gene id: 510516:AO090005001073
uniprot id: Q2UQW6
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

510516:AO090672000006
gene id: 510516:AO090672000006
uniprot id: Q2UG16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090005001278
gene id: 510516:AO090005001278
uniprot id: Q2UQE9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001076
gene id: 510516:AO090005001076
uniprot id: Q2UQW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090009000026
gene id: 510516:AO090009000026
uniprot id: Q2UV88
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090003001104
gene id: 510516:AO090003001104
uniprot id: Q2UJR6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

510516:AO090023000365
gene id: 510516:AO090023000365
uniprot id: Q2UHP3
names: Subcellular Location Annotation
messages: Secreted

510516:AO090103000016
gene id: 510516:AO090103000016
uniprot id: Q2TZ20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIMR family. LMBRD1 subfamily.
messages: Lysosome membrane
messages: Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).

510516:AO090010000696
gene id: 510516:AO090010000696
uniprot id: Q2TW58
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090005001391
gene id: 510516:AO090005001391
uniprot id: Q2UQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

510516:AO090003000568
gene id: 510516:AO090003000568
uniprot id: Q2UL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

510516:AO090005000617
gene id: 510516:AO090005000617
uniprot id: Q2US06
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

510516:AO090010000458
gene id: 510516:AO090010000458
uniprot id: Q2TWR2
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090010000564
gene id: 510516:AO090010000564
uniprot id: Q2TWG7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001504
gene id: 510516:AO090005001504
uniprot id: Q2UPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Ssu72 is required for 3'-end formation of snoRNAs (By similarity).
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (rpb1).

510516:AO090701000830
gene id: 510516:AO090701000830
uniprot id: Q2U7I1
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

510516:AO090103000222
gene id: 510516:AO090103000222
uniprot id: Q2TYJ2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090010000641
gene id: 510516:AO090010000641
uniprot id: Q2TWA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

510516:AO090001000740
gene id: 510516:AO090001000740
uniprot id: Q2UMI6
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

510516:AO090138000093
gene id: 510516:AO090138000093
uniprot id: Q2U1U5
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090124000066
gene id: 510516:AO090124000066
uniprot id: Q2U750
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000209
gene id: 510516:AO090003000209
uniprot id: Q2ULZ4
names: Similarity
messages: Belongs to the TTC36 family.

510516:AO090701000244
gene id: 510516:AO090701000244
uniprot id: Q2U8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
messages: Secreted

510516:AO090003000663
gene id: 510516:AO090003000663
uniprot id: Q2UKV2
names: Similarity
messages: Belongs to the COG3 family.

510516:AO090005000194
gene id: 510516:AO090005000194
uniprot id: Q2UT24
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

510516:AO090023000912
gene id: 510516:AO090023000912
uniprot id: Q2UGA8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

510516:AO090011000479
gene id: 510516:AO090011000479
uniprot id: Q2U0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090011000110
gene id: 510516:AO090011000110
uniprot id: Q2U1A2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090103000007
gene id: 510516:AO090103000007
uniprot id: Q2TZ28
names: Similarity
messages: Belongs to the heat shock protein 70 family.

510516:AO090038000232
gene id: 510516:AO090038000232
uniprot id: Q2U316
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
messages: Cytoplasm
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

510516:AO090701000430
gene id: 510516:AO090701000430
uniprot id: Q2U8H4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090011000345
gene id: 510516:AO090011000345
uniprot id: Q2U0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

510516:AO090009000295
gene id: 510516:AO090009000295
uniprot id: Q2UUJ1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

510516:AO090001000492
gene id: 510516:AO090001000492
uniprot id: Q2UN61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 53 family.
messages: Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.
messages: Secreted

510516:AO090005000456
gene id: 510516:AO090005000456
uniprot id: Q2USE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

510516:AO090011000781
gene id: 510516:AO090011000781
uniprot id: Q2TZN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Cytoplasm
messages: Nucleus

510516:AO090010000721
gene id: 510516:AO090010000721
uniprot id: Q2TW35
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090009000091
gene id: 510516:AO090009000091
uniprot id: Q2UV14
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090003001164
gene id: 510516:AO090003001164
uniprot id: Q2UJL4
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090001000329
gene id: 510516:AO090001000329
uniprot id: Q2UNK3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

510516:AO090010000617
gene id: 510516:AO090010000617
uniprot id: Q2TWC6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

510516:AO090005001132
gene id: 510516:AO090005001132
uniprot id: Q2UQR7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

510516:AO090003001401
gene id: 510516:AO090003001401
uniprot id: Q2UJ09
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000191
gene id: 510516:AO090102000191
uniprot id: Q2UAX8
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

510516:AO090038000585
gene id: 510516:AO090038000585
uniprot id: Q2U264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

510516:AO090012000485
gene id: 510516:AO090012000485
uniprot id: Q2UCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

510516:AO090020000106
gene id: 510516:AO090020000106
uniprot id: Q2U525
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090003001251
gene id: 510516:AO090003001251
uniprot id: Q2UJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

510516:AO090038000097
gene id: 510516:AO090038000097
uniprot id: Q2U3C5
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090005000274
gene id: 510516:AO090005000274
uniprot id: Q2USV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090120000249
gene id: 510516:AO090120000249
uniprot id: Q2U6G2
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

510516:AO090005001531
gene id: 510516:AO090005001531
uniprot id: Q2UPS2
names: Similarity
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

510516:AO090003000298
gene id: 510516:AO090003000298
uniprot id: Q2ULR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

510516:AO090113000137
gene id: 510516:AO090113000137
uniprot id: Q2U5H9
names: Biotechnology
names: Disruption Phenotype
names: Function
names: Induction
names: Subcellular Location Annotation
messages: Expression is positively regulated by the secondary metabolism general regulator laeA (PubMed:21897021). Expression is negatively regulated by the transcription factor kpeA (PubMed:30790620).
messages: Impairs the transcription of kojA and kojT, and blocks the production of kojic acid.
messages: Kojic acid can be used for several biotechnological applications, including use as an antibiotic, as an additive to prevent browning of food materials, and as an antioxidant (PubMed:17119644). Kojic acid is also interesting as an inhibitor of tyrosinase (PubMed:7714722). Finally, kojic acid has also been shown to have strong nematicidal activity (PubMed:27197670).
messages: Nucleus
messages: Transcription factor that regulates the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent.

510516:AO090001000497
gene id: 510516:AO090001000497
uniprot id: Q2UN57
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

510516:AO090120000095
gene id: 510516:AO090120000095
uniprot id: Q2U6U3
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000910
gene id: 510516:AO090011000910
uniprot id: Q2TZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450.

510516:AO090023000402
gene id: 510516:AO090023000402
uniprot id: Q2UHL3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000789
gene id: 510516:AO090005000789
uniprot id: Q2URK6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

510516:AO090020000116
gene id: 510516:AO090020000116
uniprot id: Q2U516
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

510516:AO090011000004
gene id: 510516:AO090011000004
uniprot id: Q2U1J7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090102000629
gene id: 510516:AO090102000629
uniprot id: Q2U9X3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000009
gene id: 510516:AO090020000009
uniprot id: Q2U5A6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

510516:AO090010000441
gene id: 510516:AO090010000441
uniprot id: Q2TWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

510516:AO090003000631
gene id: 510516:AO090003000631
uniprot id: Q2UKX6
names: Similarity
messages: Belongs to the GST superfamily.

510516:AO090120000208
gene id: 510516:AO090120000208
uniprot id: Q2U6J6
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

510516:AO090005001611
gene id: 510516:AO090005001611
uniprot id: Q2UPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

510516:AO090005001450
gene id: 510516:AO090005001450
uniprot id: Q2UPZ4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

510516:AO090023000227
gene id: 510516:AO090023000227
uniprot id: Q2UI16
names: Similarity
messages: Belongs to the ZPR1 family.

510516:AO090120000214
gene id: 510516:AO090120000214
uniprot id: Q2U6J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

510516:AO090023000724
gene id: 510516:AO090023000724
uniprot id: Q2UGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

510516:AO090005000738
gene id: 510516:AO090005000738
uniprot id: Q2URP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

510516:AO090005000611
gene id: 510516:AO090005000611
uniprot id: Q2US12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

510516:AO090011000025
gene id: 510516:AO090011000025
uniprot id: Q2U1H7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000495
gene id: 510516:AO090012000495
uniprot id: Q2UCQ0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by gcn5 is promoted by H3S10ph. H3K14ac can also be formed by esa1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by set2 to form H3K36me. H3K36me represses gene expression. Methylated by dot1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the dot1-mediated formation of H3K79me require H2BK123ub1 (By similarity).
messages: Nucleus
messages: Phosphorylated to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation and is required for transcriptional activation through TBP recruitment to the promoters (By similarity).
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-37; H3K36me1/2/3 = mono-, di- and trimethylated Lys-37; H3K56ac = acetylated Lys-57; H3K64ac = acetylated Lys-65; H3K79me1/2/3 = mono-, di- and trimethylated Lys-80.

510516:AO090012000436
gene id: 510516:AO090012000436
uniprot id: Q2UCV1
names: Similarity
messages: Belongs to the peptidase M16 family.

510516:AO090138000119
gene id: 510516:AO090138000119
uniprot id: Q2U1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

510516:AO090012000400
gene id: 510516:AO090012000400
uniprot id: Q2UCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

510516:AO090011000651
gene id: 510516:AO090011000651
uniprot id: Q2TZZ9
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.

510516:AO090113000064
gene id: 510516:AO090113000064
uniprot id: Q2U5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

510516:AO090701000678
gene id: 510516:AO090701000678
uniprot id: Q2U7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

510516:AO090701000658
gene id: 510516:AO090701000658
uniprot id: Q2U7X8
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090011000486
gene id: 510516:AO090011000486
uniprot id: Q2U0D3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

510516:AO090023000501
gene id: 510516:AO090023000501
uniprot id: Q2UHC4
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

510516:AO090003001140
gene id: 510516:AO090003001140
uniprot id: Q2UJN4
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

510516:AO090005001027
gene id: 510516:AO090005001027
uniprot id: Q2UR04
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000887
gene id: 510516:AO090003000887
uniprot id: Q2UKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: nucleolus

510516:AO090003001407
gene id: 510516:AO090003001407
uniprot id: Q2UJ04
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090023000543
gene id: 510516:AO090023000543
uniprot id: Q2UH87
names: Similarity
messages: Belongs to the flavin-dependent halogenase family.

510516:AO090023000977
gene id: 510516:AO090023000977
uniprot id: Q2UG50
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090005001299
gene id: 510516:AO090005001299
uniprot id: Q2UQD1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

510516:AO090103000036
gene id: 510516:AO090103000036
uniprot id: Q2TZ03
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

510516:AO090012000209
gene id: 510516:AO090012000209
uniprot id: Q2UDE1
names: Similarity
messages: Belongs to the peptidase A1 family.

510516:AO090102000349
gene id: 510516:AO090102000349
uniprot id: Q2UAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

510516:AO090102000616
gene id: 510516:AO090102000616
uniprot id: Q2U9Y5
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

510516:AO090023000752
gene id: 510516:AO090023000752
uniprot id: Q2UGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

510516:AO090701000228
gene id: 510516:AO090701000228
uniprot id: Q2U900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

510516:AO090113000158
gene id: 510516:AO090113000158
uniprot id: Q2U5F9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

510516:AO090038000395
gene id: 510516:AO090038000395
uniprot id: P41756
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

510516:AO090701000885
gene id: 510516:AO090701000885
uniprot id: Q2U7D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan (By similarity).
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Secreted

510516:AO090003001001
gene id: 510516:AO090003001001
uniprot id: Q2UK05
names: Similarity
messages: Belongs to the VPS26 family.

510516:AO090001000614
gene id: 510516:AO090001000614
uniprot id: Q2UMV1
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

510516:AO090023000474
gene id: 510516:AO090023000474
uniprot id: Q2UHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis.

510516:AO090003001099
gene id: 510516:AO090003001099
uniprot id: Q2UJS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

510516:AO090001000586
gene id: 510516:AO090001000586
uniprot id: Q2UMX2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000121
gene id: 510516:AO090026000121
uniprot id: Q2UFQ0
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

510516:AO090020000238
gene id: 510516:AO090020000238
uniprot id: Q2U4R0
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090023000830
gene id: 510516:AO090023000830
uniprot id: Q2UGI4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

510516:AO090005001174
gene id: 510516:AO090005001174
uniprot id: Q2UQN3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

510516:AO090009000260
gene id: 510516:AO090009000260
uniprot id: Q2UUM2
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
messages: Belongs to the wetA family.
messages: BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:19850144). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).
messages: Expression is controlled by abaA (PubMed:19850144).
messages: Loses conidial pigments and exhibits autolytic phenotype (PubMed:19850144).

510516:AO090003001195
gene id: 510516:AO090003001195
uniprot id: Q2UJI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090010000774
gene id: 510516:AO090010000774
uniprot id: Q2TVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

510516:AO090701000126
gene id: 510516:AO090701000126
uniprot id: Q2U991
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090102000043
gene id: 510516:AO090102000043
uniprot id: Q2UBA9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090124000037
gene id: 510516:AO090124000037
uniprot id: Q2U777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

510516:AO090026000013
gene id: 510516:AO090026000013
uniprot id: Q2UG02
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

510516:AO090003000665
gene id: 510516:AO090003000665
uniprot id: Q2UKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP9 family.
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
messages: nucleolus

510516:AO090023000861
gene id: 510516:AO090023000861
uniprot id: Q2UGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

510516:AO090011000289
gene id: 510516:AO090011000289
uniprot id: Q2U0V6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of lanosterol to form eburicol.

510516:AO090010000155
gene id: 510516:AO090010000155
uniprot id: Q2TXG4
names: Function
names: Similarity
messages: 2-methylcitrate dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).
messages: Belongs to the PrpD family.

510516:AO090012000413
gene id: 510516:AO090012000413
uniprot id: Q2UCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Cell membrane
messages: Membrane

510516:AO090120000290
gene id: 510516:AO090120000290
uniprot id: Q2U6C9
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

510516:AO090001000722
gene id: 510516:AO090001000722
uniprot id: Q2UMK3
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.

510516:AO090003001008
gene id: 510516:AO090003001008
uniprot id: Q2UJZ9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

510516:AO090012000996
gene id: 510516:AO090012000996
uniprot id: Q2UBH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090120000186
gene id: 510516:AO090120000186
uniprot id: Q2U6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

510516:AO090701000693
gene id: 510516:AO090701000693
uniprot id: Q2U7U9
names: Similarity
messages: Belongs to the DCP1 family.

510516:AO090026000080
gene id: 510516:AO090026000080
uniprot id: Q2UFT8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

510516:AO090020000539
gene id: 510516:AO090020000539
uniprot id: Q2U409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

510516:AO090011000855
gene id: 510516:AO090011000855
uniprot id: Q2TZH0
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

510516:AO090701000062
gene id: 510516:AO090701000062
uniprot id: Q2U9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

510516:AO090003000315
gene id: 510516:AO090003000315
uniprot id: Q2ULQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
messages: Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

510516:AO090011000774
gene id: 510516:AO090011000774
uniprot id: Q2TZP5
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

510516:AO090001000075
gene id: 510516:AO090001000075
uniprot id: P24021
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nuclease type I family.
messages: Binds 3 divalent metal cations.
messages: Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.
messages: Inhibited by inorganic phosphate (Pi).
messages: Monomer.

510516:AO090701000897
gene id: 510516:AO090701000897
uniprot id: Q2U7C1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005001567
gene id: 510516:AO090005001567
uniprot id: Q2UPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

510516:AO090120000099
gene id: 510516:AO090120000099
uniprot id: Q2U6U0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

510516:AO090023000807
gene id: 510516:AO090023000807
uniprot id: Q2UGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090023000324
gene id: 510516:AO090023000324
uniprot id: Q2UHT0
names: Similarity
messages: Belongs to the nuclease type I family.

510516:AO090003000777
gene id: 510516:AO090003000777
uniprot id: Q2UKJ8
names: Subcellular Location Annotation
messages: Membrane

510516:AO090120000068
gene id: 510516:AO090120000068
uniprot id: Q877A8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the catalase family.
messages: By hydrogen peroxide.
messages: Homotetramer.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide through its degradation into water and oxygen.
messages: Secreted

510516:AO090011000703
gene id: 510516:AO090011000703
uniprot id: Q2TZV6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090009000281
gene id: 510516:AO090009000281
uniprot id: Q2UUK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

510516:AO090103000023
gene id: 510516:AO090103000023
uniprot id: Q2TZ13
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

510516:AO090026000393
gene id: 510516:AO090026000393
uniprot id: Q2UF12
names: Similarity
messages: Belongs to the SDHAF4 family.

510516:AO090020000689
gene id: 510516:AO090020000689
uniprot id: Q2U3N3
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090701000685
gene id: 510516:AO090701000685
uniprot id: Q2U7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

510516:AO090005001238
gene id: 510516:AO090005001238
uniprot id: Q2UQI1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000488
gene id: 510516:AO090102000488
uniprot id: Q2UA94
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

510516:AO090009000402
gene id: 510516:AO090009000402
uniprot id: Q2UU96
names: Similarity
messages: Belongs to the KRI1 family.

510516:AO090011000938
gene id: 510516:AO090011000938
uniprot id: Q2TZA1
names: Similarity
messages: Belongs to the TIP41 family.

510516:AO090038000279
gene id: 510516:AO090038000279
uniprot id: Q2U2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: Cell membrane
messages: Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase.
messages: Membrane
messages: cell wall

510516:AO090001000064
gene id: 510516:AO090001000064
uniprot id: Q2UP91
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090138000049
gene id: 510516:AO090138000049
uniprot id: Q2U1Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

510516:AO090005000092
gene id: 510516:AO090005000092
uniprot id: Q2UTA9
names: Similarity
messages: Belongs to the rtf2 family.

510516:AO090026000441
gene id: 510516:AO090026000441
uniprot id: Q2UEX3
names: Function
names: Subcellular Location Annotation
messages: May act as a zinc-influx transporter.
messages: Membrane

510516:AO090003000045
gene id: 510516:AO090003000045
uniprot id: Q2UMD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Cell membrane
messages: Membrane
messages: cell wall

510516:AO090009000312
gene id: 510516:AO090009000312
uniprot id: Q2UUH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

510516:AO090012000711
gene id: 510516:AO090012000711
uniprot id: Q2UC74
names: Similarity
messages: Belongs to the XFP family.

510516:AO090023000240
gene id: 510516:AO090023000240
uniprot id: Q2UI03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

510516:AO090120000382
gene id: 510516:AO090120000382
uniprot id: Q2U648
names: Subcellular Location Annotation
messages: Mitochondrion

510516:AO090009000447
gene id: 510516:AO090009000447
uniprot id: Q2UU58
names: Similarity
messages: Belongs to the CNOT9 family.

510516:AO090009000648
gene id: 510516:AO090009000648
uniprot id: Q2UTP5
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

510516:AO090003000905
gene id: 510516:AO090003000905
uniprot id: Q2UK93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.
messages: Catalyzes endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues. Specific for xyloglucan and does not hydrolyze other cell wall components (By similarity).
messages: Secreted

510516:AO090012000890
gene id: 510516:AO090012000890
uniprot id: Q2UBS1
names: Similarity
messages: Belongs to the IlvD/Edd family.

510516:AO090701000842
gene id: 510516:AO090701000842
uniprot id: Q2U7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

510516:AO090120000165
gene id: 510516:AO090120000165
uniprot id: Q2U6N5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

510516:AO090012000376
gene id: 510516:AO090012000376
uniprot id: Q2UD00
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000539
gene id: 510516:AO090005000539
uniprot id: Q2US75
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090010000204
gene id: 510516:AO090010000204
uniprot id: Q2TXC1
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

510516:AO090011000145
gene id: 510516:AO090011000145
uniprot id: Q2U171
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000644
gene id: 510516:AO090102000644
uniprot id: Q2U9W1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000347
gene id: 510516:AO090026000347
uniprot id: Q2UF50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

510516:AO090023000644
gene id: 510516:AO090023000644
uniprot id: Q2UH00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
messages: Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
messages: Component of the U5 snRNP complex.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

510516:AO090102000190
gene id: 510516:AO090102000190
uniprot id: Q2UAX9
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

510516:AO090102000630
gene id: 510516:AO090102000630
uniprot id: Q2U9X2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

510516:AO090010000026
gene id: 510516:AO090010000026
uniprot id: Q2TXS8
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090023000491
gene id: 510516:AO090023000491
uniprot id: Q2UHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090005000780
gene id: 510516:AO090005000780
uniprot id: Q2URL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

510516:AO090026000553
gene id: 510516:AO090026000553
uniprot id: Q2UEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

510516:AO090003000140
gene id: 510516:AO090003000140
uniprot id: Q2UM50
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

510516:AO090023000219
gene id: 510516:AO090023000219
uniprot id: Q2UI24
names: Similarity
messages: Belongs to the SEN54 family.

510516:AO090102000516
gene id: 510516:AO090102000516
uniprot id: Q2UA71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
messages: Component of the HAT-B complex composed of at least hat1 and hat2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus
messages: Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.

510516:AO090003001338
gene id: 510516:AO090003001338
uniprot id: Q2UJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

510516:AO090012000869
gene id: 510516:AO090012000869
uniprot id: Q2UBT8
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090138000081
gene id: 510516:AO090138000081
uniprot id: Q2U1V6
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

510516:AO090003000064
gene id: 510516:AO090003000064
uniprot id: Q2UMB6
names: Similarity
messages: Belongs to the RUS1 family.

510516:AO090010000529
gene id: 510516:AO090010000529
uniprot id: Q2TWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

510516:AO090010000733
gene id: 510516:AO090010000733
uniprot id: Q2TW23
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000741
gene id: 510516:AO090003000741
uniprot id: Q2UKN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

510516:AO090012000796
gene id: 510516:AO090012000796
uniprot id: Q2UC04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules (By similarity).
messages: nucleolus

510516:AO090026000613
gene id: 510516:AO090026000613
uniprot id: Q2UEH8
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

510516:AO090026000364
gene id: 510516:AO090026000364
uniprot id: Q2UF37
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

510516:AO090009000006
gene id: 510516:AO090009000006
uniprot id: Q2UV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

510516:AO090005001196
gene id: 510516:AO090005001196
uniprot id: Q2UQL5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

510516:AO090701000640
gene id: 510516:AO090701000640
uniprot id: Q2U7Z1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

510516:AO090001000404
gene id: 510516:AO090001000404
uniprot id: Q2UND9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000470
gene id: 510516:AO090003000470
uniprot id: Q2ULB8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

510516:AO090005000973
gene id: 510516:AO090005000973
uniprot id: Q2UR47
names: Similarity
messages: Belongs to the GST superfamily.

510516:AO090001000672
gene id: 510516:AO090001000672
uniprot id: Q2UMP7
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

510516:AO090701000050
gene id: 510516:AO090701000050
uniprot id: Q2U9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090020000077
gene id: 510516:AO090020000077
uniprot id: Q2U545
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

510516:AO090001000631
gene id: 510516:AO090001000631
uniprot id: Q2UMT5
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090102000470
gene id: 510516:AO090102000470
uniprot id: Q2UAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

510516:AO090009000235
gene id: 510516:AO090009000235
uniprot id: Q2UUP3
names: Similarity
messages: Belongs to the actin family.

510516:AO090003000990
gene id: 510516:AO090003000990
uniprot id: Q7Z9L3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity).
messages: Monomer.
messages: Secreted
messages: The combination of poor nutrition conditions and attachment of mycelia to a hydrophobic solid surface appears to be a major inducing factor.

510516:AO090009000117
gene id: 510516:AO090009000117
uniprot id: Q2UUZ1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: Cell membrane
messages: Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase (By similarity).
messages: The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. There, the glucosamine-inositol phospholipid moiety is cleaved off and the GPI-modified mannoprotein is covalently attached via its lipidless GPI glycan remnant to the 1,6-beta-glucan of the outer cell wall layer (By similarity).
messages: cell wall

510516:AO090138000089
gene id: 510516:AO090138000089
uniprot id: Q2U1U8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

510516:AO090010000341
gene id: 510516:AO090010000341
uniprot id: Q2TX02
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090011000231
gene id: 510516:AO090011000231
uniprot id: Q2U0Z9
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000270
gene id: 510516:AO090701000270
uniprot id: Q2U8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

510516:AO090026000744
gene id: 510516:AO090026000744
uniprot id: Q2UE66
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
messages: Present with 1460 molecules/cell in log phase SD medium.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090011000604
gene id: 510516:AO090011000604
uniprot id: Q2U036
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

510516:AO090009000149
gene id: 510516:AO090009000149
uniprot id: Q2UUW2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

510516:AO090026000541
gene id: 510516:AO090026000541
uniprot id: Q2UEP3
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

510516:AO090023000956
gene id: 510516:AO090023000956
uniprot id: Q2UG70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with get3.
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.

510516:AO090023000897
gene id: 510516:AO090023000897
uniprot id: Q2UGC1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

510516:AO090102000125
gene id: 510516:AO090102000125
uniprot id: Q2UB37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090003000924
gene id: 510516:AO090003000924
uniprot id: Q2UK75
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090003000661
gene id: 510516:AO090003000661
uniprot id: Q2UKV4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Homotetramer.

510516:AO090020000627
gene id: 510516:AO090020000627
uniprot id: Q2U3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

510516:AO090103000105
gene id: 510516:AO090103000105
uniprot id: Q2TYU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

510516:AO090026000158
gene id: 510516:AO090026000158
uniprot id: Q2UFL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.
messages: Mitochondrion matrix

510516:AO090102000361
gene id: 510516:AO090102000361
uniprot id: Q2UAJ3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

510516:AO090701000847
gene id: 510516:AO090701000847
uniprot id: Q2U7G6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090701000557
gene id: 510516:AO090701000557
uniprot id: Q2U860
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

510516:AO090005000520
gene id: 510516:AO090005000520
uniprot id: Q2US93
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

510516:AO090103000121
gene id: 510516:AO090103000121
uniprot id: Q2TYT1
names: Similarity
messages: Belongs to the RdRP family.

510516:AO090005001148
gene id: 510516:AO090005001148
uniprot id: Q2UQQ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

510516:AO090701000277
gene id: 510516:AO090701000277
uniprot id: Q2U8V6
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000078
gene id: 510516:AO090010000078
uniprot id: Q2TXN2
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090026000185
gene id: 510516:AO090026000185
uniprot id: Q2UFJ3
names: Similarity
messages: Belongs to the SH3RF family.

510516:AO090020000668
gene id: 510516:AO090020000668
uniprot id: Q2U3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090001000049
gene id: 510516:AO090001000049
uniprot id: Q2UPA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090011000953
gene id: 510516:AO090011000953
uniprot id: Q2TZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090009000329
gene id: 510516:AO090009000329
uniprot id: Q2UUG0
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

510516:AO090003001424
gene id: 510516:AO090003001424
uniprot id: Q2UIY7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

510516:AO090005001244
gene id: 510516:AO090005001244
uniprot id: Q2UQH5
names: Similarity
messages: Belongs to the amidase family.

510516:AO090672000005
gene id: 510516:AO090672000005
uniprot id: Q2UG17
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

510516:AO090009000234
gene id: 510516:AO090009000234
uniprot id: Q2UUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

510516:AO090009000643
gene id: 510516:AO090009000643
uniprot id: Q2UTQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

510516:AO090005001262
gene id: 510516:AO090005001262
uniprot id: Q2UQG2
names: Similarity
messages: Belongs to the Cdt1 family.

510516:AO090701000002
gene id: 510516:AO090701000002
uniprot id: Q8NKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Cell membrane
messages: Probable GPI-anchored aspartic-type endopeptidase.

510516:AO090005001591
gene id: 510516:AO090005001591
uniprot id: Q2UPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

510516:AO090003001003
gene id: 510516:AO090003001003
uniprot id: Q2UK04
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

510516:AO090005000277
gene id: 510516:AO090005000277
uniprot id: Q2USV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

510516:AO090020000349
gene id: 510516:AO090020000349
uniprot id: Q8NK83
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the sulfate adenylyltransferase family.
messages: The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.

510516:AO090003000425
gene id: 510516:AO090003000425
uniprot id: Q2ULG0
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

510516:AO090011000338
gene id: 510516:AO090011000338
uniprot id: Q2U0R1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

510516:AO090005001124
gene id: 510516:AO090005001124
uniprot id: Q2UQS2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

510516:AO090023000425
gene id: 510516:AO090023000425
uniprot id: Q2UHJ3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

510516:AO090005001105
gene id: 510516:AO090005001105
uniprot id: Q2UQU0
names: Subcellular Location Annotation
messages: Cytoplasm

510516:AO090026000688
gene id: 510516:AO090026000688
uniprot id: Q2UEB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

510516:AO090003000015
gene id: 510516:AO090003000015
uniprot id: Q2UMG0
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000602
gene id: 510516:AO090011000602
uniprot id: Q2U038
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

510516:AO090003000917
gene id: 510516:AO090003000917
uniprot id: Q2UK82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

510516:AO090005001386
gene id: 510516:AO090005001386
uniprot id: Q2UQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex.
messages: trans-Golgi network

510516:AO090009000479
gene id: 510516:AO090009000479
uniprot id: Q2UU32
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000498
gene id: 510516:AO090005000498
uniprot id: Q2USB2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090120000422
gene id: 510516:AO090120000422
uniprot id: Q2U613
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

510516:AO090011000368
gene id: 510516:AO090011000368
uniprot id: Q2U0N3
names: Biotechnology
names: Function
names: Induction
names: Similarity
messages: 4-methyl-2-oxopentanoate (MOA) reductase that reduces MOA, a possible intermediate in leucine synthesis, to D-leucate in a NADPH- or NADH-dependent manner, but with a preference for NADPH (PubMed:26615399). In addition to MOA, shows broad substrate specificity toward 2-keto acids (PubMed:26615399).
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Ethyl-2-hydroxy-4-methylpentanoate (ethyl leucate) contributes to a fruity flavor in Japanese sake and the strain overexpressing morA would help to ferment high-quality sake with an excellent flavor.
messages: Leucine and 4-methyl-2-oxopentanate (MOA) increase the expression 3.1- and 4.5-fold, respectively, whereas leucate represses the expression.

510516:AO090011000428
gene id: 510516:AO090011000428
uniprot id: Q2U0I4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090001000496
gene id: 510516:AO090001000496
uniprot id: Q2UN58
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090023000710
gene id: 510516:AO090023000710
uniprot id: Q2UGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT5 family.
messages: Component of the spt4-spt5 complex. Interacts with RNA polymerase II (By similarity).
messages: Nucleus
messages: The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).

510516:AO090038000244
gene id: 510516:AO090038000244
uniprot id: Q2U306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

510516:AO090011000326
gene id: 510516:AO090011000326
uniprot id: Q2U0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

510516:AO090026000166
gene id: 510516:AO090026000166
uniprot id: Q2UFK7
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

510516:AO090023000105
gene id: 510516:AO090023000105
uniprot id: Q2UID1
names: Similarity
messages: Belongs to the FHIP family.

510516:AO090011000850
gene id: 510516:AO090011000850
uniprot id: Q2TZH5
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

510516:AO090003001488
gene id: 510516:AO090003001488
uniprot id: Q2UIT5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

510516:AO090012000227
gene id: 510516:AO090012000227
uniprot id: Q2UDC5
names: Similarity
messages: Belongs to the PhyH family.

510516:AO090003000972
gene id: 510516:AO090003000972
uniprot id: Q2UK33
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

510516:AO090003000480
gene id: 510516:AO090003000480
uniprot id: Q2ULA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

510516:AO090102000063
gene id: 510516:AO090102000063
uniprot id: Q2UB91
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

510516:AO090023000727
gene id: 510516:AO090023000727
uniprot id: Q2UGS7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

510516:AO090026000816
gene id: 510516:AO090026000816
uniprot id: Q2UDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

510516:AO090020000372
gene id: 510516:AO090020000372
uniprot id: Q2U4E8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

510516:AO090005001041
gene id: 510516:AO090005001041
uniprot id: Q2UQZ5
names: Disruption Phenotype
names: Function
names: Induction
names: Subcellular Location Annotation
messages: BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity). Required for conidiophores formation (PubMed:17213655). Controls expression of abaA (PubMed:19850144).
messages: Expression is controlled by flbA, flbS and fluG (PubMed:19850144).
messages: Leads to delayed conidia development (PubMed:17213655, PubMed:19850144).
messages: Nucleus

510516:AO090020000625
gene id: 510516:AO090020000625
uniprot id: Q2U3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

510516:AO090701000212
gene id: 510516:AO090701000212
uniprot id: Q2U915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CWC2 family.
messages: Nucleus

510516:AO090138000055
gene id: 510516:AO090138000055
uniprot id: Q2U1X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 43 family.
messages: Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
messages: Secreted

510516:AO090023000688
gene id: 510516:AO090023000688
uniprot id: Q2UGW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090001000572
gene id: 510516:AO090001000572
uniprot id: Q2UMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Mitochondrion outer membrane

510516:AO090102000149
gene id: 510516:AO090102000149
uniprot id: Q2UB17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).
messages: nucleolus

510516:AO090038000317
gene id: 510516:AO090038000317
uniprot id: Q2U2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

510516:AO090003000496
gene id: 510516:AO090003000496
uniprot id: Q2UL95
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000234
gene id: 510516:AO090020000234
uniprot id: Q2U4R4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

510516:AO090005001192
gene id: 510516:AO090005001192
uniprot id: Q2UQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090005001302
gene id: 510516:AO090005001302
uniprot id: Q2UQC8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

510516:AO090012000176
gene id: 510516:AO090012000176
uniprot id: Q2UDG9
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090001000357
gene id: 510516:AO090001000357
uniprot id: Q2UNI1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

510516:AO090026000803
gene id: 510516:AO090026000803
uniprot id: Q2UE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

510516:AO090023000536
gene id: 510516:AO090023000536
uniprot id: Q2UH92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090011000876
gene id: 510516:AO090011000876
uniprot id: Q2TZF0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

510516:AO090206000015
gene id: 510516:AO090206000015
uniprot id: Q2PIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Mitochondrion inner membrane
messages: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.

510516:AO090001000661
gene id: 510516:AO090001000661
uniprot id: Q2UMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

510516:AO090012000475
gene id: 510516:AO090012000475
uniprot id: Q2UCR8
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

510516:AO090001000189
gene id: 510516:AO090001000189
uniprot id: Q2UNX8
names: Biotechnology
names: Domain
names: Function
names: Similarity
names: Subunit
messages: AOL adopts the six-bladed beta-propeller fold and contains 6 binding sites per monomer, each located between two adjacent blades (PubMed:27318092, PubMed:28041800). The 6 binding sites that are non-equivalent, and owing to minor differences in amino-acid composition they exhibit a marked difference in specific ligand recognition (PubMed:27318092, PubMed:28041800).
messages: Belongs to the fungal fucose-specific lectin family.
messages: Homodimer (PubMed:17383961).
messages: Lectin that specifically binds to L-fucose and weakly reacts with mannose and N-acetyl-neuraminic acid (PubMed:12092808, PubMed:27318092, PubMed:28041800). Has strongest preference for the alpha-1,6-fucosylated chain (core fucose) on glycoproteins among alpha-1,2-, alpha-1,3-, alpha-1,4-, and alpha-1,6-fucosylated chains (PubMed:17383961, PubMed:19109923). Binds to fucose residues of IgE in mice and human, causing antigen-independent IgE-mediated mast cell activation and anaphylactoid reactions in mice and is possibly implicated in allergic response to Aspergillus oryzae in humans (PubMed:21790704). Induces secretion of pro-inflammatory cytokines IL6 and IL8 implicated in ocular diseases such as mycotic keratitis, probably through its interaction with host toll-like receptors TLR2 and TLR4, followed by up-regulation of pro-inflammatory cytokines (PubMed:28470344).
messages: Lectins have particular value as specific probes for investigating the distribution, structure and biological function of carbohydrate chains on the cell surface of animal, plant, and microorganism because of their specificity for defined carbohydrate structures (PubMed:17383961). FleA is suitable for detecting core fucose on cell surface glycoproteins and/or a useful vehicle for delivery of substances to the inside of cells (PubMed:17383961, PubMed:21892597).

510516:AO090012000528
gene id: 510516:AO090012000528
uniprot id: Q2UCM3
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

510516:AO090010000654
gene id: 510516:AO090010000654
uniprot id: Q2TW91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis.

510516:AO090009000589
gene id: 510516:AO090009000589
uniprot id: Q2UTU5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090005000588
gene id: 510516:AO090005000588
uniprot id: Q2US34
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

510516:AO090020000517
gene id: 510516:AO090020000517
uniprot id: Q2U428
names: Similarity
messages: Belongs to the peptidase S8 family.

510516:AO090124000083
gene id: 510516:AO090124000083
uniprot id: Q2U734
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

510516:AO090020000345
gene id: 510516:AO090020000345
uniprot id: Q2U4H1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

510516:AO090001000704
gene id: 510516:AO090001000704
uniprot id: Q2UMM1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090026000029
gene id: 510516:AO090026000029
uniprot id: Q2UFY6
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090120000371
gene id: 510516:AO090120000371
uniprot id: Q2U657
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

510516:AO090003000189
gene id: 510516:AO090003000189
uniprot id: Q2UM10
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

510516:AO090166000095
gene id: 510516:AO090166000095
uniprot id: Q2U9M2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

510516:AO090138000196
gene id: 510516:AO090138000196
uniprot id: Q2U1K8
names: Similarity
messages: Belongs to the FAH family.

510516:AO090103000166
gene id: 510516:AO090103000166
uniprot id: Q2TYP4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000950
gene id: 510516:AO090012000950
uniprot id: Q2UBL4
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

510516:AO090005000482
gene id: 510516:AO090005000482
uniprot id: Q2USC5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

510516:AO090010000392
gene id: 510516:AO090010000392
uniprot id: Q2TWW0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000079
gene id: 510516:AO090102000079
uniprot id: Q2UB76
names: Similarity
messages: Belongs to the peptidase S28 family.

510516:AO090701000034
gene id: 510516:AO090701000034
uniprot id: Q2U9H0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

510516:AO090038000565
gene id: 510516:AO090038000565
uniprot id: Q2U282
names: Similarity
messages: Belongs to the NAPRTase family.

510516:AO090120000080
gene id: 510516:AO090120000080
uniprot id: Q9Y713
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

510516:AO090011000904
gene id: 510516:AO090011000904
uniprot id: Q2TZD0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

510516:AO090001000630
gene id: 510516:AO090001000630
uniprot id: Q2UMT6
names: Similarity
messages: Belongs to the cytochrome b5 family.

510516:AO090001000307
gene id: 510516:AO090001000307
uniprot id: Q2UNM3
names: Similarity
messages: Belongs to the LOR family.

510516:AO090701000838
gene id: 510516:AO090701000838
uniprot id: Q2U7H4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

510516:AO090020000670
gene id: 510516:AO090020000670
uniprot id: Q2U3Q0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

510516:AO090023000696
gene id: 510516:AO090023000696
uniprot id: Q2UGV4
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

510516:AO090701000175
gene id: 510516:AO090701000175
uniprot id: Q2U948
names: Similarity
messages: Belongs to the PrpD family.

510516:AO090103000039
gene id: 510516:AO090103000039
uniprot id: Q2TZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

510516:AO090010000607
gene id: 510516:AO090010000607
uniprot id: Q2TWD3
names: Similarity
messages: Belongs to the multicopper oxidase family.

510516:AO090001000193
gene id: 510516:AO090001000193
uniprot id: Q2UNX5
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity).

510516:AO090009000153
gene id: 510516:AO090009000153
uniprot id: Q2UUW0
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090009000593
gene id: 510516:AO090009000593
uniprot id: Q2UTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

510516:AO090012000079
gene id: 510516:AO090012000079
uniprot id: Q2UDQ4
names: Subcellular Location Annotation
messages: Membrane

510516:AO090001000086
gene id: 510516:AO090001000086
uniprot id: Q2UP74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis.

510516:AO090010000505
gene id: 510516:AO090010000505
uniprot id: Q2TWM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

510516:AO090026000130
gene id: 510516:AO090026000130
uniprot id: Q2UFP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

510516:AO090012000416
gene id: 510516:AO090012000416
uniprot id: Q2UCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

510516:AO090010000030
gene id: 510516:AO090010000030
uniprot id: Q2TXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.
messages: Secreted

510516:AO090026000794
gene id: 510516:AO090026000794
uniprot id: Q2UE18
names: Similarity
messages: Belongs to the TPA1 family.

510516:AO090102000382
gene id: 510516:AO090102000382
uniprot id: Q2UAH5
names: Similarity
messages: Belongs to the cytochrome P450 family.

510516:AO090003000859
gene id: 510516:AO090003000859
uniprot id: Q2UKD0
names: Function
names: Similarity
messages: Belongs to the aldo/keto reductase family.
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).

510516:AO090701000809
gene id: 510516:AO090701000809
uniprot id: Q2U7K0
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000824
gene id: 510516:AO090003000824
uniprot id: Q2UKF9
names: Similarity
messages: Belongs to the VPS8 family.

510516:AO090001000300
gene id: 510516:AO090001000300
uniprot id: Q2UNM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

510516:AO090103000052
gene id: 510516:AO090103000052
uniprot id: Q2TYY8
names: Similarity
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

510516:AO090005000352
gene id: 510516:AO090005000352
uniprot id: Q2USP0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

510516:AO090003000280
gene id: 510516:AO090003000280
uniprot id: Q2ULT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, atg13 is also required for glycogen storage during stationary phase (By similarity).
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Cytoplasm
messages: Interacts with atg1 to form the atg1-atg13 kinase complex.
messages: Preautophagosomal structure

510516:AO090103000033
gene id: 510516:AO090103000033
uniprot id: Q2TZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIP5 family.
messages: Cytoplasm
messages: May negatively regulate the snf1 kinase.

510516:AO090020000148
gene id: 510516:AO090020000148
uniprot id: Q2U4Y8
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

510516:AO090001000584
gene id: 510516:AO090001000584
uniprot id: Q2UMX4
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

510516:AO090011000370
gene id: 510516:AO090011000370
uniprot id: Q2U0N1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090020000036
gene id: 510516:AO090020000036
uniprot id: Q2U582
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000315
gene id: 510516:AO090005000315
uniprot id: Q2USS1
names: Similarity
messages: Belongs to the peptidase M20A family.

510516:AO090009000355
gene id: 510516:AO090009000355
uniprot id: Q2UUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.
messages: Membrane

510516:AO090012000408
gene id: 510516:AO090012000408
uniprot id: Q2UCX6
names: Similarity
messages: Belongs to the threonine aldolase family.

510516:AO090020000324
gene id: 510516:AO090020000324
uniprot id: Q2U4I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090102000577
gene id: 510516:AO090102000577
uniprot id: Q2UA20
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

510516:AO090023000723
gene id: 510516:AO090023000723
uniprot id: Q2UGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

510516:AO090023000757
gene id: 510516:AO090023000757
uniprot id: Q2UGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
messages: Mitochondrion membrane

510516:AO090005000815
gene id: 510516:AO090005000815
uniprot id: Q2URI5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.

510516:AO090103000248
gene id: 510516:AO090103000248
uniprot id: Q2TYH1
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000968
gene id: 510516:AO090005000968
uniprot id: Q2UR51
names: Subcellular Location Annotation
messages: Membrane

510516:AO090020000575
gene id: 510516:AO090020000575
uniprot id: Q2U3X8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

510516:AO090026000843
gene id: 510516:AO090026000843
uniprot id: Q2UDX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

510516:AO090026000345
gene id: 510516:AO090026000345
uniprot id: Q2UF52
names: Subcellular Location Annotation
messages: nucleolus

510516:AO090103000342
gene id: 510516:AO090103000342
uniprot id: Q2TY91
names: Similarity
messages: Belongs to the group II decarboxylase family.

510516:AO090012000945
gene id: 510516:AO090012000945
uniprot id: Q2UBL9
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000149
gene id: 510516:AO090011000149
uniprot id: Q2U168
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

510516:AO090120000188
gene id: 510516:AO090120000188
uniprot id: Q2U6L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

510516:AO090113000038
gene id: 510516:AO090113000038
uniprot id: Q2U5R5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000051
gene id: 510516:AO090003000051
uniprot id: Q2UMC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

510516:AO090012000870
gene id: 510516:AO090012000870
uniprot id: Q2UBT7
names: Similarity
messages: Belongs to the profilin family.

510516:AO090023000510
gene id: 510516:AO090023000510
uniprot id: Q2UHB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).
messages: Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
messages: Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes (By similarity).
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

510516:AO090005001441
gene id: 510516:AO090005001441
uniprot id: Q2UQ02
names: Similarity
messages: Belongs to the activator 1 small subunits family.

510516:AO090023000997
gene id: 510516:AO090023000997
uniprot id: Q2UG33
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

510516:AO090038000376
gene id: 510516:AO090038000376
uniprot id: Q2U2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

510516:AO090038000442
gene id: 510516:AO090038000442
uniprot id: Q2U2I5
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090003001411
gene id: 510516:AO090003001411
uniprot id: Q2UJ00
names: Similarity
messages: Belongs to the amidase family.

510516:AO090038000333
gene id: 510516:AO090038000333
uniprot id: Q2U2S9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

510516:AO090701000664
gene id: 510516:AO090701000664
uniprot id: Q2U7X5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

510516:AO090023000318
gene id: 510516:AO090023000318
uniprot id: Q2UHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

510516:AO090020000207
gene id: 510516:AO090020000207
uniprot id: Q2U4T9
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

510516:AO090009000680
gene id: 510516:AO090009000680
uniprot id: Q2UTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

510516:AO090009000188
gene id: 510516:AO090009000188
uniprot id: Q2UUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

510516:AO090020000058
gene id: 510516:AO090020000058
uniprot id: Q2U561
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).

510516:AO090102000245
gene id: 510516:AO090102000245
uniprot id: Q2UAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

510516:AO090003000501
gene id: 510516:AO090003000501
uniprot id: Q2UL91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

510516:AO090166000068
gene id: 510516:AO090166000068
uniprot id: Q2U9P6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

510516:AO090005001482
gene id: 510516:AO090005001482
uniprot id: Q2UPW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S9B family.
messages: Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
messages: Vacuole membrane

510516:AO090023000639
gene id: 510516:AO090023000639
uniprot id: Q2UH05
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090001000482
gene id: 510516:AO090001000482
uniprot id: Q2UN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Cytoplasm
messages: Nucleus

510516:AO090005001240
gene id: 510516:AO090005001240
uniprot id: Q2UQH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.

510516:AO090001000462
gene id: 510516:AO090001000462
uniprot id: Q2UN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

510516:AO090009000067
gene id: 510516:AO090009000067
uniprot id: Q2UV32
names: Similarity
messages: Belongs to the multicopper oxidase family.

510516:AO090011000605
gene id: 510516:AO090011000605
uniprot id: Q2U035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

510516:AO090120000137
gene id: 510516:AO090120000137
uniprot id: Q2U6Q5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

510516:AO090020000210
gene id: 510516:AO090020000210
uniprot id: Q2U4T6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

510516:AO090003000310
gene id: 510516:AO090003000310
uniprot id: Q2ULQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
messages: Mitochondrion inner membrane

510516:AO090003001329
gene id: 510516:AO090003001329
uniprot id: Q2UJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

510516:AO090701000145
gene id: 510516:AO090701000145
uniprot id: Q2U972
names: Similarity
messages: Belongs to the MAK16 family.

510516:AO090005000605
gene id: 510516:AO090005000605
uniprot id: Q2US18
names: Similarity
messages: Belongs to the CBF/MAK21 family.

510516:AO090010000477
gene id: 510516:AO090010000477
uniprot id: Q2TWP4
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

510516:AO090012000084
gene id: 510516:AO090012000084
uniprot id: Q2UDQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

510516:AO090005001018
gene id: 510516:AO090005001018
uniprot id: Q2UR12
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

510516:AO090003000212
gene id: 510516:AO090003000212
uniprot id: Q2ULZ1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

510516:AO090003000668
gene id: 510516:AO090003000668
uniprot id: Q2UKU7
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

510516:AO090001000459
gene id: 510516:AO090001000459
uniprot id: Q2UN89
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

510516:AO090005001157
gene id: 510516:AO090005001157
uniprot id: Q2UQP7
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

510516:AO090023000164
gene id: 510516:AO090023000164
uniprot id: Q2UI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

510516:AO090001000133
gene id: 510516:AO090001000133
uniprot id: Q2UP32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Secreted
messages: Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.

510516:AO090005000760
gene id: 510516:AO090005000760
uniprot id: Q2URM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex, and the protein sar1.

510516:AO090102000532
gene id: 510516:AO090102000532
uniprot id: Q2UA59
names: Subcellular Location Annotation
messages: Membrane

510516:AO090701000789
gene id: 510516:AO090701000789
uniprot id: Q2U7L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.

510516:AO090011000918
gene id: 510516:AO090011000918
uniprot id: Q2TZB8
names: Subcellular Location Annotation
messages: Cell membrane

510516:AO090011000813
gene id: 510516:AO090011000813
uniprot id: Q2TZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

510516:AO090020000067
gene id: 510516:AO090020000067
uniprot id: Q2U554
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

510516:AO090701000274
gene id: 510516:AO090701000274
uniprot id: Q2U8V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

510516:AO090023000220
gene id: 510516:AO090023000220
uniprot id: Q2UI23
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.

510516:AO090026000458
gene id: 510516:AO090026000458
uniprot id: Q2UEV9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

510516:AO090003000630
gene id: 510516:AO090003000630
uniprot id: Q2UKX7
names: Subcellular Location Annotation
messages: Membrane

510516:AO090003000174
gene id: 510516:AO090003000174
uniprot id: Q2UM22
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

510516:AO090012000725
gene id: 510516:AO090012000725
uniprot id: Q2UC62
names: Similarity
messages: Belongs to the alkaline phosphatase family.

510516:AO090003001343
gene id: 510516:AO090003001343
uniprot id: Q2UJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

510516:AO090009000092
gene id: 510516:AO090009000092
uniprot id: Q2UV13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

510516:AO090020000403
gene id: 510516:AO090020000403
uniprot id: Q2U4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

510516:AO090120000348
gene id: 510516:AO090120000348
uniprot id: Q2U678
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

510516:AO090005001652
gene id: 510516:AO090005001652
uniprot id: Q2UPG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

510516:AO090011000648
gene id: 510516:AO090011000648
uniprot id: Q2U002
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

510516:AO090003001132
gene id: 510516:AO090003001132
uniprot id: Q2UJP2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

510516:AO090020000008
gene id: 510516:AO090020000008
uniprot id: Q2U5A7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

510516:AO090103000082
gene id: 510516:AO090103000082
uniprot id: Q2TYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

510516:AO090701000347
gene id: 510516:AO090701000347
uniprot id: Q2U8P3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000963
gene id: 510516:AO090005000963
uniprot id: Q2UR56
names: Subcellular Location Annotation
messages: Membrane

510516:AO090012000208
gene id: 510516:AO090012000208
uniprot id: Q2UDE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of nbp35 and two labile, bridging clusters between subunits of the nbp35-cfd1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 nbp35 and 2 cfd1 chains.

510516:AO090026000561
gene id: 510516:AO090026000561
uniprot id: Q2UEM4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

510516:AO090005001279
gene id: 510516:AO090005001279
uniprot id: Q2UQE8
names: Function
names: Subcellular Location Annotation
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

510516:AO090005001311
gene id: 510516:AO090005001311
uniprot id: Q2UQC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

510516:AO090003000443
gene id: 510516:AO090003000443
uniprot id: Q2ULE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

510516:AO090026000404
gene id: 510516:AO090026000404
uniprot id: Q2UF05
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

510516:AO090102000127
gene id: 510516:AO090102000127
uniprot id: Q2UB35
names: Similarity
messages: Belongs to the PHF5 family.

510516:AO090102000010
gene id: 510516:AO090102000010
uniprot id: Q2UBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pectinesterase family.
messages: Involved in maceration and soft-rotting of plant tissue.
messages: Secreted

510516:AO090103000267
gene id: 510516:AO090103000267
uniprot id: Q2TYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

510516:AO090120000079
gene id: 510516:AO090120000079
uniprot id: Q2U6V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

510516:AO090023000223
gene id: 510516:AO090023000223
uniprot id: Q2UI20
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

510516:AO090005000736
gene id: 510516:AO090005000736
uniprot id: Q2URP9
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

510516:AO090005000614
gene id: 510516:AO090005000614
uniprot id: Q2US09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

510516:AO090010000051
gene id: 510516:AO090010000051
uniprot id: Q2TXQ5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

510516:AO090011000329
gene id: 510516:AO090011000329
uniprot id: Q2U0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

510516:AO090038000352
gene id: 510516:AO090038000352
uniprot id: Q2U2R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

510516:AO090010000482
gene id: 510516:AO090010000482
uniprot id: Q2TWP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

510516:AO090023000923
gene id: 510516:AO090023000923
uniprot id: Q2UG98
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

510516:AO090102000111
gene id: 510516:AO090102000111
uniprot id: Q2UB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

510516:AO090020000386
gene id: 510516:AO090020000386
uniprot id: Q2U4D5
names: Subcellular Location Annotation
messages: Membrane

510516:AO090102000523
gene id: 510516:AO090102000523
uniprot id: Q2UA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

510516:AO090023000749
gene id: 510516:AO090023000749
uniprot id: Q2UGR1
names: Function
messages: Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

510516:AO090001000243
gene id: 510516:AO090001000243
uniprot id: Q2UNT1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

510516:AO090005001213
gene id: 510516:AO090005001213
uniprot id: Q2UQK2
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090005000361
gene id: 510516:AO090005000361
uniprot id: Q2USN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

510516:AO090010000776
gene id: 510516:AO090010000776
uniprot id: Q2TVY0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

510516:AO090011000595
gene id: 510516:AO090011000595
uniprot id: Q2U045
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

510516:AO090701000893
gene id: 510516:AO090701000893
uniprot id: Q2U7C5
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

510516:AO090023000409
gene id: 510516:AO090023000409
uniprot id: Q2UHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

510516:AO090206000053
gene id: 510516:AO090206000053
uniprot id: Q2PIU9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

510516:AO090009000568
gene id: 510516:AO090009000568
uniprot id: Q2UTW1
names: Similarity
messages: Belongs to the citrate synthase family.

510516:AO090011000513
gene id: 510516:AO090011000513
uniprot id: Q2U0A9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

510516:AO090011000589
gene id: 510516:AO090011000589
uniprot id: Q2U049
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

510516:AO090120000264
gene id: 510516:AO090120000264
uniprot id: Q2U6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

510516:AO090003001345
gene id: 510516:AO090003001345
uniprot id: Q2UJ60
names: Subcellular Location Annotation
messages: Nucleus

510516:AO090011000291
gene id: 510516:AO090011000291
uniprot id: Q2U0V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity).
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

510516:AO090103000214
gene id: 510516:AO090103000214
uniprot id: Q2TYK0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

510516:AO090009000454
gene id: 510516:AO090009000454
uniprot id: Q2UU54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
messages: The GINS complex plays an essential role in the initiation of DNA replication.

510516:AO090020000103
gene id: 510516:AO090020000103
uniprot id: Q2U527
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

510516:AO090005000532
gene id: 510516:AO090005000532
uniprot id: Q2US82
names: Similarity
messages: Belongs to the PAL/histidase family.

510516:AO090026000472
gene id: 510516:AO090026000472
uniprot id: Q2UEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

510516:AO090012000469
gene id: 510516:AO090012000469
uniprot id: Q2UCS2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090005000110
gene id: 510516:AO090005000110
uniprot id: Q2UT91
names: Subcellular Location Annotation
messages: Membrane

510516:AO090038000064
gene id: 510516:AO090038000064
uniprot id: Q2U3F2
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090012000623
gene id: 510516:AO090012000623
uniprot id: Q2UCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

510516:AO090009000609
gene id: 510516:AO090009000609
uniprot id: Q2UTS6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

510516:AO090001000093
gene id: 510516:AO090001000093
uniprot id: Q2UP67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.
messages: Cytoplasm
messages: Homodimer. May form higher order oligomers.

510516:AO090038000341
gene id: 510516:AO090038000341
uniprot id: Q2U2S3
names: Similarity
messages: Belongs to the CBF/MAK21 family.

510516:AO090020000146
gene id: 510516:AO090020000146
uniprot id: Q2U4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

510516:AO090005001495
gene id: 510516:AO090005001495
uniprot id: Q2UPV3
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000768
gene id: 510516:AO090010000768
uniprot id: Q2TVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

510516:AO090701000187
gene id: 510516:AO090701000187
uniprot id: Q2U937
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

510516:AO090012000638
gene id: 510516:AO090012000638
uniprot id: Q2UCD3
names: Similarity
messages: Belongs to the CAP family.

510516:AO090038000334
gene id: 510516:AO090038000334
uniprot id: Q2U2S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

510516:AO090701000784
gene id: 510516:AO090701000784
uniprot id: Q2U7M1
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

510516:AO090026000372
gene id: 510516:AO090026000372
uniprot id: Q2UF30
names: Similarity
messages: Belongs to the ATPase delta chain family.

510516:AO090009000138
gene id: 510516:AO090009000138
uniprot id: Q2UUX2
names: Subcellular Location Annotation
messages: Membrane

510516:AO090010000161
gene id: 510516:AO090010000161
uniprot id: Q2TXG0
names: Function
names: Similarity
messages: Belongs to the PrpD family.
messages: Cis-aconitate decarboxylase-like protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).

510516:AO090020000380
gene id: 510516:AO090020000380
uniprot id: Q2U4E0
names: Similarity
messages: Belongs to the NRP synthetase family.

510516:AO090010000533
gene id: 510516:AO090010000533
uniprot id: Q2TWJ4
names: Similarity
messages: Belongs to the NmrA-type oxidoreductase family.

510516:AO090012000418
gene id: 510516:AO090012000418
uniprot id: Q2UCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

510516:AO090005000758
gene id: 510516:AO090005000758
uniprot id: Q2URN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

510516:AO090001000298
gene id: 510516:AO090001000298
uniprot id: Q2UNN0
names: Subcellular Location Annotation
messages: Membrane