504728:K649 RS06005
gene id: 504728:K649_RS06005
uniprot id: A0A806CWV9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS03710
gene id: 504728:K649_RS03710
uniprot id: D3PPV4
names: Similarity
messages: Belongs to the TrpF family.

504728:K649 RS05160
gene id: 504728:K649_RS05160
uniprot id: D3PQY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

504728:K649 RS10120
gene id: 504728:K649_RS10120
uniprot id: D3PMC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

504728:K649 RS03560
gene id: 504728:K649_RS03560
uniprot id: D3PPE2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

504728:K649 RS12205
gene id: 504728:K649_RS12205
uniprot id: D3PTN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

504728:K649 RS11030
gene id: 504728:K649_RS11030
uniprot id: D3PLF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

504728:K649 RS06120
gene id: 504728:K649_RS06120
uniprot id: D3PRG8
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

504728:K649 RS07540
gene id: 504728:K649_RS07540
uniprot id: D3PQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS12815
gene id: 504728:K649_RS12815
uniprot id: D3PTB0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

504728:K649 RS11975
gene id: 504728:K649_RS11975
uniprot id: D3PTS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

504728:K649 RS12900
gene id: 504728:K649_RS12900
uniprot id: D3PT94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

504728:K649 RS02025
gene id: 504728:K649_RS02025
uniprot id: D3PMT4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

504728:K649 RS07695
gene id: 504728:K649_RS07695
uniprot id: D3PQ76
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13350
gene id: 504728:K649_RS13350
uniprot id: D3PT03
names: Similarity
messages: Belongs to the transketolase family.

504728:K649 RS05350
gene id: 504728:K649_RS05350
uniprot id: D3PR20
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

504728:K649 RS11190
gene id: 504728:K649_RS11190
uniprot id: D3PKZ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

504728:K649 RS02750
gene id: 504728:K649_RS02750
uniprot id: D3PNK1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

504728:K649 RS00105
gene id: 504728:K649_RS00105
uniprot id: A0A806CMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

504728:K649 RS13380
gene id: 504728:K649_RS13380
uniprot id: D3PSZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

504728:K649 RS05315
gene id: 504728:K649_RS05315
uniprot id: A0A806CWJ0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

504728:K649 RS03975
gene id: 504728:K649_RS03975
uniprot id: D3PQ09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

504728:K649 RS06020
gene id: 504728:K649_RS06020
uniprot id: D3PRE8
names: Similarity
messages: Belongs to the FGGY kinase family.

504728:K649 RS02985
gene id: 504728:K649_RS02985
uniprot id: D3PP30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

504728:K649 RS07775
gene id: 504728:K649_RS07775
uniprot id: D3PPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

504728:K649 RS09530
gene id: 504728:K649_RS09530
uniprot id: A0A806CN36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS09870
gene id: 504728:K649_RS09870
uniprot id: D3PMH6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

504728:K649 RS03570
gene id: 504728:K649_RS03570
uniprot id: D3PPE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

504728:K649 RS00380
gene id: 504728:K649_RS00380
uniprot id: D3PL41
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS15235
gene id: 504728:K649_RS15235
uniprot id: D3PRY4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

504728:K649 RS14950
gene id: 504728:K649_RS14950
uniprot id: D3PS40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

504728:K649 RS09280
gene id: 504728:K649_RS09280
uniprot id: D3PN74
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS10195
gene id: 504728:K649_RS10195
uniprot id: D3PMB0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

504728:K649 RS03330
gene id: 504728:K649_RS03330
uniprot id: D3PP96
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

504728:K649 RS07100
gene id: 504728:K649_RS07100
uniprot id: D3PKC9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13570
gene id: 504728:K649_RS13570
uniprot id: D3PSW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

504728:K649 RS10560
gene id: 504728:K649_RS10560
uniprot id: A0A806CPU3
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS15255
gene id: 504728:K649_RS15255
uniprot id: D3PRY0
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

504728:K649 RS12035
gene id: 504728:K649_RS12035
uniprot id: D3PTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

504728:K649 RS08905
gene id: 504728:K649_RS08905
uniprot id: A0A806DD20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

504728:K649 RS13015
gene id: 504728:K649_RS13015
uniprot id: A0A806CNQ7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

504728:K649 RS13315
gene id: 504728:K649_RS13315
uniprot id: D3PT09
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

504728:K649 RS13935
gene id: 504728:K649_RS13935
uniprot id: D3PSN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

504728:K649 RS14250
gene id: 504728:K649_RS14250
uniprot id: D3PSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

504728:K649 RS12955
gene id: 504728:K649_RS12955
uniprot id: D3PT82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

504728:K649 RS12820
gene id: 504728:K649_RS12820
uniprot id: D3PTA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

504728:K649 RS09840
gene id: 504728:K649_RS09840
uniprot id: A0A806D0A1
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01555
gene id: 504728:K649_RS01555
uniprot id: D3PM58
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

504728:K649 RS14585
gene id: 504728:K649_RS14585
uniprot id: D3PSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

504728:K649 RS06445
gene id: 504728:K649_RS06445
uniprot id: A0A806DI81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

504728:K649 RS00690
gene id: 504728:K649_RS00690
uniprot id: D3PLA5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

504728:K649 RS10365
gene id: 504728:K649_RS10365
uniprot id: D3PM77
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

504728:K649 RS04280
gene id: 504728:K649_RS04280
uniprot id: D3PQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS08030
gene id: 504728:K649_RS08030
uniprot id: A0A806D1C9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS11805
gene id: 504728:K649_RS11805
uniprot id: D3PTW2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

504728:K649 RS00385
gene id: 504728:K649_RS00385
uniprot id: D3PL42
names: Subunit
messages: Homodimer.

504728:K649 RS12800
gene id: 504728:K649_RS12800
uniprot id: D3PTB3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

504728:K649 RS05275
gene id: 504728:K649_RS05275
uniprot id: D3PR07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS01785
gene id: 504728:K649_RS01785
uniprot id: D3PMN8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS14700
gene id: 504728:K649_RS14700
uniprot id: D3PS88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS03415
gene id: 504728:K649_RS03415
uniprot id: M9X621
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

504728:K649 RS04370
gene id: 504728:K649_RS04370
uniprot id: D3PQH7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

504728:K649 RS14780
gene id: 504728:K649_RS14780
uniprot id: A0A806DIS8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

504728:K649 RS14385
gene id: 504728:K649_RS14385
uniprot id: D3PSF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

504728:K649 RS07895
gene id: 504728:K649_RS07895
uniprot id: D3PPQ9
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

504728:K649 RS13035
gene id: 504728:K649_RS13035
uniprot id: D3PT66
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

504728:K649 RS13055
gene id: 504728:K649_RS13055
uniprot id: D3PT62
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

504728:K649 RS03820
gene id: 504728:K649_RS03820
uniprot id: D3PPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

504728:K649 RS13610
gene id: 504728:K649_RS13610
uniprot id: D3PSV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

504728:K649 RS07260
gene id: 504728:K649_RS07260
uniprot id: D3PQG0
names: Similarity
messages: Belongs to the ParB family.

504728:K649 RS08785
gene id: 504728:K649_RS08785
uniprot id: A0A806CNF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

504728:K649 RS07115
gene id: 504728:K649_RS07115
uniprot id: D3PKC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05115
gene id: 504728:K649_RS05115
uniprot id: A0A806CWF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS06125
gene id: 504728:K649_RS06125
uniprot id: A0A806CPV3
names: Similarity
messages: Belongs to the Skp family.

504728:K649 RS11165
gene id: 504728:K649_RS11165
uniprot id: D3PL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS10530
gene id: 504728:K649_RS10530
uniprot id: M9XBI6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

504728:K649 RS14730
gene id: 504728:K649_RS14730
uniprot id: D3PS82
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS05260
gene id: 504728:K649_RS05260
uniprot id: D3PR04
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

504728:K649 RS09320
gene id: 504728:K649_RS09320
uniprot id: D3PN65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

504728:K649 RS12970
gene id: 504728:K649_RS12970
uniprot id: D3PT79
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

504728:K649 RS08220
gene id: 504728:K649_RS08220
uniprot id: A0A806D184
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

504728:K649 RS11265
gene id: 504728:K649_RS11265
uniprot id: D3PKY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

504728:K649 RS10160
gene id: 504728:K649_RS10160
uniprot id: D3PMB7
names: Similarity
messages: Belongs to the UPF0166 family.

504728:K649 RS00440
gene id: 504728:K649_RS00440
uniprot id: D3PL53
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

504728:K649 RS03510
gene id: 504728:K649_RS03510
uniprot id: D3PPD2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS11200
gene id: 504728:K649_RS11200
uniprot id: D3PKZ3
names: Similarity
messages: Belongs to the FUN14 family.

504728:K649 RS11900
gene id: 504728:K649_RS11900
uniprot id: D3PTU3
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13640
gene id: 504728:K649_RS13640
uniprot id: D3PSU7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

504728:K649 RS03930
gene id: 504728:K649_RS03930
uniprot id: A0A806DGP5
names: Similarity
messages: Belongs to the RecJ family.

504728:K649 RS05640
gene id: 504728:K649_RS05640
uniprot id: D3PR73
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS04970
gene id: 504728:K649_RS04970
uniprot id: D3PQU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

504728:K649 RS01585
gene id: 504728:K649_RS01585
uniprot id: D3PMJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS11085
gene id: 504728:K649_RS11085
uniprot id: D3PLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS05120
gene id: 504728:K649_RS05120
uniprot id: D3PQX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS13790
gene id: 504728:K649_RS13790
uniprot id: D3PSR8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

504728:K649 RS01105
gene id: 504728:K649_RS01105
uniprot id: A0A806DEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

504728:K649 RS02695
gene id: 504728:K649_RS02695
uniprot id: D3PNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

504728:K649 RS03145
gene id: 504728:K649_RS03145
uniprot id: D3PP62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

504728:K649 RS01190
gene id: 504728:K649_RS01190
uniprot id: A0A806D5T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS04985
gene id: 504728:K649_RS04985
uniprot id: D3PQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

504728:K649 RS08555
gene id: 504728:K649_RS08555
uniprot id: D3PNZ9
names: Similarity
messages: Belongs to the peptidase S58 family.

504728:K649 RS10210
gene id: 504728:K649_RS10210
uniprot id: D3PMA7
names: Similarity
messages: Belongs to the UxaA family.

504728:K649 RS00170
gene id: 504728:K649_RS00170
uniprot id: D3PKL5
names: Similarity
messages: Belongs to the P(II) protein family.

504728:K649 RS10215
gene id: 504728:K649_RS10215
uniprot id: D3PMA6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

504728:K649 RS06685
gene id: 504728:K649_RS06685
uniprot id: D3PRS9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

504728:K649 RS06635
gene id: 504728:K649_RS06635
uniprot id: D3PRR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

504728:K649 RS11460
gene id: 504728:K649_RS11460
uniprot id: D3PKT9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

504728:K649 RS03790
gene id: 504728:K649_RS03790
uniprot id: D3PPX0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

504728:K649 RS02650
gene id: 504728:K649_RS02650
uniprot id: A0A806CL10
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

504728:K649 RS06980
gene id: 504728:K649_RS06980
uniprot id: M9XDJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

504728:K649 RS14145
gene id: 504728:K649_RS14145
uniprot id: D3PSJ7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

504728:K649 RS10855
gene id: 504728:K649_RS10855
uniprot id: D3PLJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

504728:K649 RS10485
gene id: 504728:K649_RS10485
uniprot id: D3PLR8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS13420
gene id: 504728:K649_RS13420
uniprot id: D3PSY7
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14575
gene id: 504728:K649_RS14575
uniprot id: D3PSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

504728:K649 RS01880
gene id: 504728:K649_RS01880
uniprot id: D3PMQ5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

504728:K649 RS12975
gene id: 504728:K649_RS12975
uniprot id: D3PT78
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09170
gene id: 504728:K649_RS09170
uniprot id: D3PN96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

504728:K649 RS07655
gene id: 504728:K649_RS07655
uniprot id: D3PQ84
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

504728:K649 RS06015
gene id: 504728:K649_RS06015
uniprot id: A0A806CKK7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

504728:K649 RS09225
gene id: 504728:K649_RS09225
uniprot id: D3PN85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09480
gene id: 504728:K649_RS09480
uniprot id: D3PN33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

504728:K649 RS01690
gene id: 504728:K649_RS01690
uniprot id: A0A806DGY8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09490
gene id: 504728:K649_RS09490
uniprot id: D3PN31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS12370
gene id: 504728:K649_RS12370
uniprot id: D3PTK0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

504728:K649 RS04705
gene id: 504728:K649_RS04705
uniprot id: D3PQP3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

504728:K649 RS13155
gene id: 504728:K649_RS13155
uniprot id: D3PT41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

504728:K649 RS05470
gene id: 504728:K649_RS05470
uniprot id: D3PR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

504728:K649 RS06510
gene id: 504728:K649_RS06510
uniprot id: D3PRP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

504728:K649 RS00630
gene id: 504728:K649_RS00630
uniprot id: D3PL94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

504728:K649 RS09635
gene id: 504728:K649_RS09635
uniprot id: D3PN02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

504728:K649 RS07730
gene id: 504728:K649_RS07730
uniprot id: D3PPT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS10515
gene id: 504728:K649_RS10515
uniprot id: D3PLR2
names: Similarity
messages: Belongs to the threonine synthase family.

504728:K649 RS03805
gene id: 504728:K649_RS03805
uniprot id: D3PPX3
names: Similarity
messages: Belongs to the histone deacetylase family.

504728:K649 RS10435
gene id: 504728:K649_RS10435
uniprot id: D3PM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

504728:K649 RS12030
gene id: 504728:K649_RS12030
uniprot id: D3PTR7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

504728:K649 RS03540
gene id: 504728:K649_RS03540
uniprot id: D3PPD8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

504728:K649 RS08535
gene id: 504728:K649_RS08535
uniprot id: D3PP03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

504728:K649 RS00625
gene id: 504728:K649_RS00625
uniprot id: D3PL93
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

504728:K649 RS09515
gene id: 504728:K649_RS09515
uniprot id: D3PN26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

504728:K649 RS12040
gene id: 504728:K649_RS12040
uniprot id: D3PTR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

504728:K649 RS14305
gene id: 504728:K649_RS14305
uniprot id: D3PSG6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

504728:K649 RS11940
gene id: 504728:K649_RS11940
uniprot id: D3PTT5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

504728:K649 RS07910
gene id: 504728:K649_RS07910
uniprot id: D3PPQ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS04925
gene id: 504728:K649_RS04925
uniprot id: D3PQT7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell outer membrane
messages: Membrane
messages: Periplasm

504728:K649 RS08800
gene id: 504728:K649_RS08800
uniprot id: D3PNV2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

504728:K649 RS00165
gene id: 504728:K649_RS00165
uniprot id: D3PKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS02235
gene id: 504728:K649_RS02235
uniprot id: D3PMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

504728:K649 RS14775
gene id: 504728:K649_RS14775
uniprot id: D3PS73
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

504728:K649 RS08995
gene id: 504728:K649_RS08995
uniprot id: A0A806DLR4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

504728:K649 RS10110
gene id: 504728:K649_RS10110
uniprot id: A0A806CQ11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

504728:K649 RS08295
gene id: 504728:K649_RS08295
uniprot id: M9XDG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

504728:K649 RS07480
gene id: 504728:K649_RS07480
uniprot id: D3PQB9
names: Similarity
messages: Belongs to the RutC family.

504728:K649 RS10450
gene id: 504728:K649_RS10450
uniprot id: D3PLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

504728:K649 RS09910
gene id: 504728:K649_RS09910
uniprot id: D3PMG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

504728:K649 RS14500
gene id: 504728:K649_RS14500
uniprot id: M9XDM9
names: Similarity
messages: Belongs to the peptidase M16 family.

504728:K649 RS10850
gene id: 504728:K649_RS10850
uniprot id: D3PLJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

504728:K649 RS09420
gene id: 504728:K649_RS09420
uniprot id: D3PN45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

504728:K649 RS14815
gene id: 504728:K649_RS14815
uniprot id: A0A806CXM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

504728:K649 RS04700
gene id: 504728:K649_RS04700
uniprot id: D3PQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

504728:K649 RS10935
gene id: 504728:K649_RS10935
uniprot id: D3PLH7
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS02925
gene id: 504728:K649_RS02925
uniprot id: D3PNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

504728:K649 RS08925
gene id: 504728:K649_RS08925
uniprot id: D3PNS7
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

504728:K649 RS08485
gene id: 504728:K649_RS08485
uniprot id: D3PP13
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

504728:K649 RS11795
gene id: 504728:K649_RS11795
uniprot id: D3PTW4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

504728:K649 RS12185
gene id: 504728:K649_RS12185
uniprot id: D3PTN7
names: Similarity
messages: Belongs to the thioredoxin family.

504728:K649 RS11410
gene id: 504728:K649_RS11410
uniprot id: D3PKU9
names: Similarity
messages: Belongs to the UPF0173 family.

504728:K649 RS01675
gene id: 504728:K649_RS01675
uniprot id: D3PML6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

504728:K649 RS10245
gene id: 504728:K649_RS10245
uniprot id: D3PMA0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

504728:K649 RS06320
gene id: 504728:K649_RS06320
uniprot id: A0A806CSL0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

504728:K649 RS11435
gene id: 504728:K649_RS11435
uniprot id: D3PKU4
names: Similarity
messages: Belongs to the GSP E family.

504728:K649 RS00245
gene id: 504728:K649_RS00245
uniprot id: D3PL13
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

504728:K649 RS03815
gene id: 504728:K649_RS03815
uniprot id: D3PPX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

504728:K649 RS09620
gene id: 504728:K649_RS09620
uniprot id: D3PN05
names: Similarity
messages: Belongs to the peptidase S1C family.

504728:K649 RS09535
gene id: 504728:K649_RS09535
uniprot id: D3PN22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

504728:K649 RS03780
gene id: 504728:K649_RS03780
uniprot id: D3PPW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

504728:K649 RS10140
gene id: 504728:K649_RS10140
uniprot id: D3PMC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

504728:K649 RS00145
gene id: 504728:K649_RS00145
uniprot id: D3PKK9
names: Similarity
messages: Belongs to the peptidase M29 family.

504728:K649 RS14310
gene id: 504728:K649_RS14310
uniprot id: D3PSG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

504728:K649 RS09455
gene id: 504728:K649_RS09455
uniprot id: D3PN38
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

504728:K649 RS09925
gene id: 504728:K649_RS09925
uniprot id: D3PMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

504728:K649 RS02950
gene id: 504728:K649_RS02950
uniprot id: D3PNP1
names: Similarity
messages: Belongs to the fabD family.

504728:K649 RS01710
gene id: 504728:K649_RS01710
uniprot id: D3PMM3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

504728:K649 RS06165
gene id: 504728:K649_RS06165
uniprot id: A0A806CKM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

504728:K649 RS00910
gene id: 504728:K649_RS00910
uniprot id: D3PLT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

504728:K649 RS06425
gene id: 504728:K649_RS06425
uniprot id: D3PRM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

504728:K649 RS02850
gene id: 504728:K649_RS02850
uniprot id: D3PNM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

504728:K649 RS12085
gene id: 504728:K649_RS12085
uniprot id: D3PTQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

504728:K649 RS04575
gene id: 504728:K649_RS04575
uniprot id: D3PQL8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

504728:K649 RS01530
gene id: 504728:K649_RS01530
uniprot id: D3PM53
names: Similarity
messages: Belongs to the cytochrome P450 family.

504728:K649 RS05015
gene id: 504728:K649_RS05015
uniprot id: D3PQV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09465
gene id: 504728:K649_RS09465
uniprot id: D3PN36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

504728:K649 RS10010
gene id: 504728:K649_RS10010
uniprot id: D3PME7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

504728:K649 RS09430
gene id: 504728:K649_RS09430
uniprot id: D3PN43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

504728:K649 RS14655
gene id: 504728:K649_RS14655
uniprot id: D3PS97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

504728:K649 RS03950
gene id: 504728:K649_RS03950
uniprot id: D3PQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

504728:K649 RS12495
gene id: 504728:K649_RS12495
uniprot id: D3PTH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Membrane

504728:K649 RS15210
gene id: 504728:K649_RS15210
uniprot id: D3PRY8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01545
gene id: 504728:K649_RS01545
uniprot id: D3PM56
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

504728:K649 RS11830
gene id: 504728:K649_RS11830
uniprot id: D3PTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

504728:K649 RS12790
gene id: 504728:K649_RS12790
uniprot id: D3PTB5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

504728:K649 RS02860
gene id: 504728:K649_RS02860
uniprot id: D3PNM3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS04430
gene id: 504728:K649_RS04430
uniprot id: D3PQI9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS12855
gene id: 504728:K649_RS12855
uniprot id: D3PTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS03785
gene id: 504728:K649_RS03785
uniprot id: D3PPW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS01540
gene id: 504728:K649_RS01540
uniprot id: D3PM55
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

504728:K649 RS05555
gene id: 504728:K649_RS05555
uniprot id: D3PR60
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

504728:K649 RS09240
gene id: 504728:K649_RS09240
uniprot id: D3PN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS06310
gene id: 504728:K649_RS06310
uniprot id: A0A806DHN3
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01215
gene id: 504728:K649_RS01215
uniprot id: D3PLZ0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

504728:K649 RS14525
gene id: 504728:K649_RS14525
uniprot id: D3PSC2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

504728:K649 RS09865
gene id: 504728:K649_RS09865
uniprot id: D3PMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS01325
gene id: 504728:K649_RS01325
uniprot id: D3PM12
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

504728:K649 RS04435
gene id: 504728:K649_RS04435
uniprot id: D3PQJ0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

504728:K649 RS11140
gene id: 504728:K649_RS11140
uniprot id: D3PL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS06095
gene id: 504728:K649_RS06095
uniprot id: D3PRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS05240
gene id: 504728:K649_RS05240
uniprot id: D3PR00
names: Similarity
messages: Belongs to the peptidase S1C family.

504728:K649 RS04615
gene id: 504728:K649_RS04615
uniprot id: D3PQM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

504728:K649 RS09450
gene id: 504728:K649_RS09450
uniprot id: D3PN39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

504728:K649 RS14235
gene id: 504728:K649_RS14235
uniprot id: D3PSH9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS12295
gene id: 504728:K649_RS12295
uniprot id: A0A806CYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

504728:K649 RS14215
gene id: 504728:K649_RS14215
uniprot id: M9XI46
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

504728:K649 RS05675
gene id: 504728:K649_RS05675
uniprot id: A0A806CMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS06210
gene id: 504728:K649_RS06210
uniprot id: D3PRI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

504728:K649 RS09405
gene id: 504728:K649_RS09405
uniprot id: A0A806DLW5
names: Similarity
messages: Belongs to the SCO1/2 family.

504728:K649 RS11380
gene id: 504728:K649_RS11380
uniprot id: D3PKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS00185
gene id: 504728:K649_RS00185
uniprot id: D3PKL8
names: Similarity
messages: Belongs to the universal stress protein A family.

504728:K649 RS12450
gene id: 504728:K649_RS12450
uniprot id: D3PTI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

504728:K649 RS08570
gene id: 504728:K649_RS08570
uniprot id: D3PNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS08965
gene id: 504728:K649_RS08965
uniprot id: D3PNR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

504728:K649 RS04320
gene id: 504728:K649_RS04320
uniprot id: D3PQG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS07735
gene id: 504728:K649_RS07735
uniprot id: D3PPT7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

504728:K649 RS03265
gene id: 504728:K649_RS03265
uniprot id: D3PP84
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

504728:K649 RS04000
gene id: 504728:K649_RS04000
uniprot id: A0A806CJS0
names: Similarity
messages: Belongs to the peptidase S8 family.

504728:K649 RS12950
gene id: 504728:K649_RS12950
uniprot id: D3PT83
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

504728:K649 RS08315
gene id: 504728:K649_RS08315
uniprot id: D3PPH5
names: Similarity
messages: Belongs to the glutamine synthetase family.

504728:K649 RS07235
gene id: 504728:K649_RS07235
uniprot id: A0A806DFN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

504728:K649 RS07455
gene id: 504728:K649_RS07455
uniprot id: D3PQC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

504728:K649 RS08790
gene id: 504728:K649_RS08790
uniprot id: M9X9C7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

504728:K649 RS13895
gene id: 504728:K649_RS13895
uniprot id: D3PSP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

504728:K649 RS04325
gene id: 504728:K649_RS04325
uniprot id: D3PQG8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

504728:K649 RS07550
gene id: 504728:K649_RS07550
uniprot id: D3PQA5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS00460
gene id: 504728:K649_RS00460
uniprot id: D3PL57
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

504728:K649 RS09560
gene id: 504728:K649_RS09560
uniprot id: D3PN16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

504728:K649 RS07725
gene id: 504728:K649_RS07725
uniprot id: D3PPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

504728:K649 RS09125
gene id: 504728:K649_RS09125
uniprot id: D3PNA6
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

504728:K649 RS14650
gene id: 504728:K649_RS14650
uniprot id: D3PS98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

504728:K649 RS05525
gene id: 504728:K649_RS05525
uniprot id: D3PR54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

504728:K649 RS06610
gene id: 504728:K649_RS06610
uniprot id: D3PRR4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

504728:K649 RS14180
gene id: 504728:K649_RS14180
uniprot id: D3PSJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS06465
gene id: 504728:K649_RS06465
uniprot id: D3PRN6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

504728:K649 RS01745
gene id: 504728:K649_RS01745
uniprot id: D3PMN0
names: Similarity
messages: Belongs to the CutA family.

504728:K649 RS10775
gene id: 504728:K649_RS10775
uniprot id: D3PLK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

504728:K649 RS10315
gene id: 504728:K649_RS10315
uniprot id: D3PM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

504728:K649 RS08540
gene id: 504728:K649_RS08540
uniprot id: M9XAE4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

504728:K649 RS11175
gene id: 504728:K649_RS11175
uniprot id: D3PKZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

504728:K649 RS01265
gene id: 504728:K649_RS01265
uniprot id: D3PM00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

504728:K649 RS05940
gene id: 504728:K649_RS05940
uniprot id: D3PRD2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

504728:K649 RS05490
gene id: 504728:K649_RS05490
uniprot id: D3PR47
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS04225
gene id: 504728:K649_RS04225
uniprot id: D3PQ55
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05690
gene id: 504728:K649_RS05690
uniprot id: D3PR83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

504728:K649 RS11500
gene id: 504728:K649_RS11500
uniprot id: D3PKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS09605
gene id: 504728:K649_RS09605
uniprot id: D3PN08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

504728:K649 RS15200
gene id: 504728:K649_RS15200
uniprot id: D3PRZ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

504728:K649 RS00140
gene id: 504728:K649_RS00140
uniprot id: D3PKK8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

504728:K649 RS07575
gene id: 504728:K649_RS07575
uniprot id: D3PQA0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

504728:K649 RS11245
gene id: 504728:K649_RS11245
uniprot id: D3PKY4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

504728:K649 RS14205
gene id: 504728:K649_RS14205
uniprot id: A0A806CXW5
names: Similarity
messages: Belongs to the ycf81 family.

504728:K649 RS05955
gene id: 504728:K649_RS05955
uniprot id: D3PRD5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

504728:K649 RS05500
gene id: 504728:K649_RS05500
uniprot id: D3PR49
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

504728:K649 RS13230
gene id: 504728:K649_RS13230
uniprot id: D3PT26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS04755
gene id: 504728:K649_RS04755
uniprot id: D3PQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS14920
gene id: 504728:K649_RS14920
uniprot id: D3PS46
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

504728:K649 RS10865
gene id: 504728:K649_RS10865
uniprot id: D3PLJ1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

504728:K649 RS04080
gene id: 504728:K649_RS04080
uniprot id: D3PQ30
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

504728:K649 RS04485
gene id: 504728:K649_RS04485
uniprot id: A0A806CLU4
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

504728:K649 RS06870
gene id: 504728:K649_RS06870
uniprot id: D3PKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

504728:K649 RS04365
gene id: 504728:K649_RS04365
uniprot id: D3PQH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS15115
gene id: 504728:K649_RS15115
uniprot id: A0A806CL09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

504728:K649 RS03455
gene id: 504728:K649_RS03455
uniprot id: D3PPC1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

504728:K649 RS00265
gene id: 504728:K649_RS00265
uniprot id: D3PL17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

504728:K649 RS08230
gene id: 504728:K649_RS08230
uniprot id: D3PPJ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

504728:K649 RS06325
gene id: 504728:K649_RS06325
uniprot id: D3PRK9
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

504728:K649 RS00885
gene id: 504728:K649_RS00885
uniprot id: D3PLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

504728:K649 RS07290
gene id: 504728:K649_RS07290
uniprot id: D3PQF4
names: Similarity
messages: Belongs to the threonine aldolase family.

504728:K649 RS06205
gene id: 504728:K649_RS06205
uniprot id: D3PRI5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09945
gene id: 504728:K649_RS09945
uniprot id: D3PMG0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

504728:K649 RS07935
gene id: 504728:K649_RS07935
uniprot id: D3PPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS00470
gene id: 504728:K649_RS00470
uniprot id: D3PL59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

504728:K649 RS13690
gene id: 504728:K649_RS13690
uniprot id: D3PST7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

504728:K649 RS00255
gene id: 504728:K649_RS00255
uniprot id: D3PL15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

504728:K649 RS05365
gene id: 504728:K649_RS05365
uniprot id: D3PR22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

504728:K649 RS03840
gene id: 504728:K649_RS03840
uniprot id: A0A806CQG1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

504728:K649 RS03110
gene id: 504728:K649_RS03110
uniprot id: D3PP55
names: Similarity
messages: Belongs to the thioesterase PaaI family.

504728:K649 RS02005
gene id: 504728:K649_RS02005
uniprot id: D3PMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

504728:K649 RS10725
gene id: 504728:K649_RS10725
uniprot id: A0A806CVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

504728:K649 RS10340
gene id: 504728:K649_RS10340
uniprot id: A0A806CUX5
names: Similarity
messages: Belongs to the EfeM/EfeO family.

504728:K649 RS06115
gene id: 504728:K649_RS06115
uniprot id: D3PRG7
names: Similarity
messages: Belongs to the peptidase S8 family.

504728:K649 RS13050
gene id: 504728:K649_RS13050
uniprot id: D3PT63
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

504728:K649 RS05530
gene id: 504728:K649_RS05530
uniprot id: D3PR55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

504728:K649 RS11040
gene id: 504728:K649_RS11040
uniprot id: D3PLF6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

504728:K649 RS02720
gene id: 504728:K649_RS02720
uniprot id: D3PNJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

504728:K649 RS09520
gene id: 504728:K649_RS09520
uniprot id: D3PN25
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

504728:K649 RS04945
gene id: 504728:K649_RS04945
uniprot id: D3PQU1
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS03245
gene id: 504728:K649_RS03245
uniprot id: D3PP80
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

504728:K649 RS08575
gene id: 504728:K649_RS08575
uniprot id: D3PNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS14670
gene id: 504728:K649_RS14670
uniprot id: A0A806CS97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS01780
gene id: 504728:K649_RS01780
uniprot id: D3PMN7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

504728:K649 RS03715
gene id: 504728:K649_RS03715
uniprot id: D3PPV5
names: Similarity
messages: Belongs to the peptidase S8 family.

504728:K649 RS14415
gene id: 504728:K649_RS14415
uniprot id: D3PSE4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

504728:K649 RS01615
gene id: 504728:K649_RS01615
uniprot id: D3PMK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

504728:K649 RS06675
gene id: 504728:K649_RS06675
uniprot id: D3PRS7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

504728:K649 RS10235
gene id: 504728:K649_RS10235
uniprot id: M9XA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS14040
gene id: 504728:K649_RS14040
uniprot id: D3PSL8
names: Subcellular Location Annotation
messages: Cytoplasm

504728:K649 RS05575
gene id: 504728:K649_RS05575
uniprot id: D3PR64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

504728:K649 RS08105
gene id: 504728:K649_RS08105
uniprot id: D3PPL9
names: Similarity
messages: Belongs to the universal stress protein A family.

504728:K649 RS00665
gene id: 504728:K649_RS00665
uniprot id: D3PLA0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

504728:K649 RS13130
gene id: 504728:K649_RS13130
uniprot id: D3PT46
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

504728:K649 RS07345
gene id: 504728:K649_RS07345
uniprot id: D3PQE6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

504728:K649 RS14785
gene id: 504728:K649_RS14785
uniprot id: D3PS71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

504728:K649 RS02865
gene id: 504728:K649_RS02865
uniprot id: D3PNM4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS12965
gene id: 504728:K649_RS12965
uniprot id: D3PT80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

504728:K649 RS08795
gene id: 504728:K649_RS08795
uniprot id: D3PNV3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

504728:K649 RS07265
gene id: 504728:K649_RS07265
uniprot id: D3PQF9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14705
gene id: 504728:K649_RS14705
uniprot id: D3PS87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS15050
gene id: 504728:K649_RS15050
uniprot id: D3PS20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS04770
gene id: 504728:K649_RS04770
uniprot id: D3PQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

504728:K649 RS02935
gene id: 504728:K649_RS02935
uniprot id: D3PNN8
names: Subcellular Location Annotation
messages: Cytoplasm

504728:K649 RS01775
gene id: 504728:K649_RS01775
uniprot id: A0A806CQC8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

504728:K649 RS13505
gene id: 504728:K649_RS13505
uniprot id: D3PSX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

504728:K649 RS13255
gene id: 504728:K649_RS13255
uniprot id: D3PT21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

504728:K649 RS11320
gene id: 504728:K649_RS11320
uniprot id: D3PKW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

504728:K649 RS05165
gene id: 504728:K649_RS05165
uniprot id: D3PQY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

504728:K649 RS01650
gene id: 504728:K649_RS01650
uniprot id: D3PML1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

504728:K649 RS11020
gene id: 504728:K649_RS11020
uniprot id: D3PLG0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

504728:K649 RS08255
gene id: 504728:K649_RS08255
uniprot id: A0A806CXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS07025
gene id: 504728:K649_RS07025
uniprot id: D3PKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS11905
gene id: 504728:K649_RS11905
uniprot id: D3PTU2
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS05090
gene id: 504728:K649_RS05090
uniprot id: D3PQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

504728:K649 RS11985
gene id: 504728:K649_RS11985
uniprot id: D3PTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

504728:K649 RS12395
gene id: 504728:K649_RS12395
uniprot id: A0A806CLZ1
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

504728:K649 RS10115
gene id: 504728:K649_RS10115
uniprot id: D3PMC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

504728:K649 RS14755
gene id: 504728:K649_RS14755
uniprot id: D3PS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

504728:K649 RS10130
gene id: 504728:K649_RS10130
uniprot id: D3PMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

504728:K649 RS05730
gene id: 504728:K649_RS05730
uniprot id: D3PR91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

504728:K649 RS03130
gene id: 504728:K649_RS03130
uniprot id: D3PP59
names: Similarity
messages: Belongs to the RecO family.

504728:K649 RS13115
gene id: 504728:K649_RS13115
uniprot id: D3PT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

504728:K649 RS00760
gene id: 504728:K649_RS00760
uniprot id: D3PLB8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

504728:K649 RS13800
gene id: 504728:K649_RS13800
uniprot id: D3PSR5
names: Similarity
messages: Belongs to the group II decarboxylase family.

504728:K649 RS10610
gene id: 504728:K649_RS10610
uniprot id: D3PLP2
names: Similarity
messages: Belongs to the peptidase U62 family.

504728:K649 RS08455
gene id: 504728:K649_RS08455
uniprot id: D3PP19
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

504728:K649 RS02965
gene id: 504728:K649_RS02965
uniprot id: D3PP26
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

504728:K649 RS10100
gene id: 504728:K649_RS10100
uniprot id: D3PMC9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

504728:K649 RS08430
gene id: 504728:K649_RS08430
uniprot id: D3PP21
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

504728:K649 RS13270
gene id: 504728:K649_RS13270
uniprot id: D3PT18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09110
gene id: 504728:K649_RS09110
uniprot id: A0A806DCY2
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS02780
gene id: 504728:K649_RS02780
uniprot id: D3PNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS07645
gene id: 504728:K649_RS07645
uniprot id: D3PQ87
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

504728:K649 RS01345
gene id: 504728:K649_RS01345
uniprot id: D3PM16
names: Similarity
messages: Belongs to the peptidase S16 family.

504728:K649 RS09735
gene id: 504728:K649_RS09735
uniprot id: D3PMY2
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS15120
gene id: 504728:K649_RS15120
uniprot id: D3PS06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

504728:K649 RS03965
gene id: 504728:K649_RS03965
uniprot id: D3PQ07
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09540
gene id: 504728:K649_RS09540
uniprot id: D3PN21
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

504728:K649 RS11870
gene id: 504728:K649_RS11870
uniprot id: D3PTU9
names: Similarity
messages: Belongs to the ComB family.

504728:K649 RS00640
gene id: 504728:K649_RS00640
uniprot id: D3PL96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

504728:K649 RS14220
gene id: 504728:K649_RS14220
uniprot id: D3PSI2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

504728:K649 RS05480
gene id: 504728:K649_RS05480
uniprot id: D3PR45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

504728:K649 RS13635
gene id: 504728:K649_RS13635
uniprot id: D3PSU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

504728:K649 RS03290
gene id: 504728:K649_RS03290
uniprot id: D3PP89
names: Similarity
messages: Belongs to the UPF0102 family.

504728:K649 RS14740
gene id: 504728:K649_RS14740
uniprot id: D3PS80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

504728:K649 RS03365
gene id: 504728:K649_RS03365
uniprot id: D3PPA3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

504728:K649 RS01645
gene id: 504728:K649_RS01645
uniprot id: A0A806DFB5
names: Similarity
messages: Belongs to the peptidase S41A family.

504728:K649 RS14110
gene id: 504728:K649_RS14110
uniprot id: D3PSK4
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13980
gene id: 504728:K649_RS13980
uniprot id: A0A806CNC8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

504728:K649 RS02670
gene id: 504728:K649_RS02670
uniprot id: D3PNI6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

504728:K649 RS05430
gene id: 504728:K649_RS05430
uniprot id: A0A806CWL0
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14105
gene id: 504728:K649_RS14105
uniprot id: D3PSK5
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14820
gene id: 504728:K649_RS14820
uniprot id: D3PS64
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

504728:K649 RS09445
gene id: 504728:K649_RS09445
uniprot id: D3PN40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

504728:K649 RS06865
gene id: 504728:K649_RS06865
uniprot id: D3PKH6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

504728:K649 RS08625
gene id: 504728:K649_RS08625
uniprot id: D3PNY5
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS15220
gene id: 504728:K649_RS15220
uniprot id: M9XAP2
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS06700
gene id: 504728:K649_RS06700
uniprot id: D3PRT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS02740
gene id: 504728:K649_RS02740
uniprot id: D3PNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

504728:K649 RS10295
gene id: 504728:K649_RS10295
uniprot id: D3PM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

504728:K649 RS09495
gene id: 504728:K649_RS09495
uniprot id: D3PN30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

504728:K649 RS15005
gene id: 504728:K649_RS15005
uniprot id: D3PS29
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS14480
gene id: 504728:K649_RS14480
uniprot id: D3PSD1
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01900
gene id: 504728:K649_RS01900
uniprot id: A0A806DH35
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14210
gene id: 504728:K649_RS14210
uniprot id: A0A806CSI2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

504728:K649 RS04040
gene id: 504728:K649_RS04040
uniprot id: D3PQ22
names: Similarity
messages: Belongs to the BshC family.

504728:K649 RS00285
gene id: 504728:K649_RS00285
uniprot id: D3PL21
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14015
gene id: 504728:K649_RS14015
uniprot id: D3PSM3
names: Similarity
messages: Belongs to the TPP enzyme family.

504728:K649 RS13370
gene id: 504728:K649_RS13370
uniprot id: D3PSZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

504728:K649 RS11045
gene id: 504728:K649_RS11045
uniprot id: D3PLF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

504728:K649 RS08210
gene id: 504728:K649_RS08210
uniprot id: D3PPJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

504728:K649 RS04230
gene id: 504728:K649_RS04230
uniprot id: D3PQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

504728:K649 RS02045
gene id: 504728:K649_RS02045
uniprot id: M9X6B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

504728:K649 RS01740
gene id: 504728:K649_RS01740
uniprot id: D3PMM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

504728:K649 RS10800
gene id: 504728:K649_RS10800
uniprot id: D3PLK4
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS07030
gene id: 504728:K649_RS07030
uniprot id: D3PKE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS15065
gene id: 504728:K649_RS15065
uniprot id: D3PS17
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

504728:K649 RS06650
gene id: 504728:K649_RS06650
uniprot id: D3PRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS06485
gene id: 504728:K649_RS06485
uniprot id: D3PRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

504728:K649 RS03895
gene id: 504728:K649_RS03895
uniprot id: D3PPZ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

504728:K649 RS13145
gene id: 504728:K649_RS13145
uniprot id: D3PT43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

504728:K649 RS13220
gene id: 504728:K649_RS13220
uniprot id: D3PT28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS14185
gene id: 504728:K649_RS14185
uniprot id: D3PSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS04780
gene id: 504728:K649_RS04780
uniprot id: D3PQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

504728:K649 RS02995
gene id: 504728:K649_RS02995
uniprot id: D3PP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

504728:K649 RS10905
gene id: 504728:K649_RS10905
uniprot id: D3PLI3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

504728:K649 RS12250
gene id: 504728:K649_RS12250
uniprot id: D3PTM4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

504728:K649 RS01685
gene id: 504728:K649_RS01685
uniprot id: D3PML8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

504728:K649 RS07250
gene id: 504728:K649_RS07250
uniprot id: A0A806DN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

504728:K649 RS01655
gene id: 504728:K649_RS01655
uniprot id: D3PML2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

504728:K649 RS12100
gene id: 504728:K649_RS12100
uniprot id: M9XCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

504728:K649 RS13820
gene id: 504728:K649_RS13820
uniprot id: D3PSR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09955
gene id: 504728:K649_RS09955
uniprot id: D3PMF8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09940
gene id: 504728:K649_RS09940
uniprot id: D3PMG1
names: Similarity
messages: Belongs to the UPF0502 family.

504728:K649 RS00565
gene id: 504728:K649_RS00565
uniprot id: A0A806CP36
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS06185
gene id: 504728:K649_RS06185
uniprot id: D3PRI1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS06090
gene id: 504728:K649_RS06090
uniprot id: D3PRG2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

504728:K649 RS05245
gene id: 504728:K649_RS05245
uniprot id: D3PR01
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS09565
gene id: 504728:K649_RS09565
uniprot id: D3PN15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

504728:K649 RS09175
gene id: 504728:K649_RS09175
uniprot id: D3PN95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

504728:K649 RS14560
gene id: 504728:K649_RS14560
uniprot id: D3PSB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

504728:K649 RS11025
gene id: 504728:K649_RS11025
uniprot id: A0A806CMG6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

504728:K649 RS10700
gene id: 504728:K649_RS10700
uniprot id: D3PLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

504728:K649 RS09580
gene id: 504728:K649_RS09580
uniprot id: D3PN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS13960
gene id: 504728:K649_RS13960
uniprot id: D3PSN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

504728:K649 RS00355
gene id: 504728:K649_RS00355
uniprot id: D3PL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS08020
gene id: 504728:K649_RS08020
uniprot id: D3PPN6
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS05040
gene id: 504728:K649_RS05040
uniprot id: A0A806CM42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

504728:K649 RS14595
gene id: 504728:K649_RS14595
uniprot id: D3PSA8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

504728:K649 RS09525
gene id: 504728:K649_RS09525
uniprot id: D3PN24
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS11395
gene id: 504728:K649_RS11395
uniprot id: A0A806DBM6
names: Similarity
messages: Belongs to the GSP E family.

504728:K649 RS12190
gene id: 504728:K649_RS12190
uniprot id: D3PTN6
names: Similarity
messages: Belongs to the cytochrome P450 family.

504728:K649 RS13415
gene id: 504728:K649_RS13415
uniprot id: D3PSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

504728:K649 RS10660
gene id: 504728:K649_RS10660
uniprot id: D3PLN2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

504728:K649 RS13755
gene id: 504728:K649_RS13755
uniprot id: D3PSS4
names: Similarity
messages: Belongs to the UPF0303 family.

504728:K649 RS11875
gene id: 504728:K649_RS11875
uniprot id: D3PTU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS12410
gene id: 504728:K649_RS12410
uniprot id: D3PTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

504728:K649 RS14240
gene id: 504728:K649_RS14240
uniprot id: D3PSH8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS11915
gene id: 504728:K649_RS11915
uniprot id: D3PTU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

504728:K649 RS06665
gene id: 504728:K649_RS06665
uniprot id: A0A806CX75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS01455
gene id: 504728:K649_RS01455
uniprot id: D3PM38
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01895
gene id: 504728:K649_RS01895
uniprot id: D3PMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS02855
gene id: 504728:K649_RS02855
uniprot id: D3PNM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

504728:K649 RS01035
gene id: 504728:K649_RS01035
uniprot id: D3PLV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

504728:K649 RS09815
gene id: 504728:K649_RS09815
uniprot id: D3PMI7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

504728:K649 RS01600
gene id: 504728:K649_RS01600
uniprot id: M9X9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

504728:K649 RS11055
gene id: 504728:K649_RS11055
uniprot id: D3PLF3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

504728:K649 RS11550
gene id: 504728:K649_RS11550
uniprot id: A0A806DKK1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

504728:K649 RS06340
gene id: 504728:K649_RS06340
uniprot id: D3PRL2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS13645
gene id: 504728:K649_RS13645
uniprot id: D3PSU6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

504728:K649 RS10840
gene id: 504728:K649_RS10840
uniprot id: D3PLJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

504728:K649 RS06055
gene id: 504728:K649_RS06055
uniprot id: A0A806CWW8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

504728:K649 RS06305
gene id: 504728:K649_RS06305
uniprot id: D3PRK5
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13885
gene id: 504728:K649_RS13885
uniprot id: D3PSP9
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

504728:K649 RS00260
gene id: 504728:K649_RS00260
uniprot id: A0A806CME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

504728:K649 RS06885
gene id: 504728:K649_RS06885
uniprot id: D3PKH2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

504728:K649 RS01695
gene id: 504728:K649_RS01695
uniprot id: D3PMM0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

504728:K649 RS03830
gene id: 504728:K649_RS03830
uniprot id: A0A806DGM5
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

504728:K649 RS04210
gene id: 504728:K649_RS04210
uniprot id: A0A806CVU0
names: Similarity
messages: Belongs to the universal stress protein A family.

504728:K649 RS09305
gene id: 504728:K649_RS09305
uniprot id: A0A806DLZ0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

504728:K649 RS14895
gene id: 504728:K649_RS14895
uniprot id: A0A806DK18
names: Similarity
messages: Belongs to the peptidase S8 family.

504728:K649 RS09330
gene id: 504728:K649_RS09330
uniprot id: D3PN63
names: Cofactor
messages: Binds 1 FAD per subunit.

504728:K649 RS09655
gene id: 504728:K649_RS09655
uniprot id: A0A806DN85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

504728:K649 RS13385
gene id: 504728:K649_RS13385
uniprot id: D3PSZ5
names: Similarity
messages: Belongs to the IMPACT family.

504728:K649 RS07800
gene id: 504728:K649_RS07800
uniprot id: A0A806CU33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS12055
gene id: 504728:K649_RS12055
uniprot id: D3PTR2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

504728:K649 RS04060
gene id: 504728:K649_RS04060
uniprot id: D3PQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

504728:K649 RS10885
gene id: 504728:K649_RS10885
uniprot id: D3PLI7
names: Similarity
messages: Belongs to the DapA family.

504728:K649 RS00580
gene id: 504728:K649_RS00580
uniprot id: D3PL84
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

504728:K649 RS06230
gene id: 504728:K649_RS06230
uniprot id: A0A806CMJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

504728:K649 RS01980
gene id: 504728:K649_RS01980
uniprot id: D3PMS5
names: Similarity
messages: Belongs to the hemerythrin family.

504728:K649 RS11715
gene id: 504728:K649_RS11715
uniprot id: D3PKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

504728:K649 RS07770
gene id: 504728:K649_RS07770
uniprot id: D3PPT2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

504728:K649 RS11205
gene id: 504728:K649_RS11205
uniprot id: D3PKZ2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

504728:K649 RS09920
gene id: 504728:K649_RS09920
uniprot id: A0A806CWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

504728:K649 RS04120
gene id: 504728:K649_RS04120
uniprot id: D3PQ37
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS12215
gene id: 504728:K649_RS12215
uniprot id: A0A806DLJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS07410
gene id: 504728:K649_RS07410
uniprot id: D3PQD3
names: Similarity
messages: Belongs to the peptidase C40 family.

504728:K649 RS12115
gene id: 504728:K649_RS12115
uniprot id: D3PTQ0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

504728:K649 RS09105
gene id: 504728:K649_RS09105
uniprot id: D3PNB0
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS08910
gene id: 504728:K649_RS08910
uniprot id: D3PNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

504728:K649 RS07740
gene id: 504728:K649_RS07740
uniprot id: D3PPT6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

504728:K649 RS12390
gene id: 504728:K649_RS12390
uniprot id: D3PTJ8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS11445
gene id: 504728:K649_RS11445
uniprot id: D3PKU2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

504728:K649 RS07605
gene id: 504728:K649_RS07605
uniprot id: D3PQ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

504728:K649 RS00635
gene id: 504728:K649_RS00635
uniprot id: D3PL95
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

504728:K649 RS04380
gene id: 504728:K649_RS04380
uniprot id: D3PQH9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

504728:K649 RS14790
gene id: 504728:K649_RS14790
uniprot id: D3PS70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

504728:K649 RS12520
gene id: 504728:K649_RS12520
uniprot id: D3PTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

504728:K649 RS12905
gene id: 504728:K649_RS12905
uniprot id: D3PT93
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS11505
gene id: 504728:K649_RS11505
uniprot id: D3PKT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

504728:K649 RS11385
gene id: 504728:K649_RS11385
uniprot id: D3PKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

504728:K649 RS08525
gene id: 504728:K649_RS08525
uniprot id: D3PP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

504728:K649 RS01770
gene id: 504728:K649_RS01770
uniprot id: D3PMN5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

504728:K649 RS14515
gene id: 504728:K649_RS14515
uniprot id: A0A806CSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

504728:K649 RS08425
gene id: 504728:K649_RS08425
uniprot id: D3PP22
names: Similarity
messages: Belongs to the DEAD box helicase family.

504728:K649 RS09045
gene id: 504728:K649_RS09045
uniprot id: D3PNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

504728:K649 RS12075
gene id: 504728:K649_RS12075
uniprot id: D3PTQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

504728:K649 RS09640
gene id: 504728:K649_RS09640
uniprot id: D3PN01
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

504728:K649 RS08395
gene id: 504728:K649_RS08395
uniprot id: A0A806CQT9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

504728:K649 RS04100
gene id: 504728:K649_RS04100
uniprot id: D3PQ33
names: Similarity
messages: Belongs to the HepT RNase toxin family.

504728:K649 RS03760
gene id: 504728:K649_RS03760
uniprot id: D3PPW4
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS10650
gene id: 504728:K649_RS10650
uniprot id: D3PLN4
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS03955
gene id: 504728:K649_RS03955
uniprot id: D3PQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

504728:K649 RS05610
gene id: 504728:K649_RS05610
uniprot id: D3PR67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

504728:K649 RS07420
gene id: 504728:K649_RS07420
uniprot id: D3PQD1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

504728:K649 RS09730
gene id: 504728:K649_RS09730
uniprot id: D3PMY3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

504728:K649 RS13955
gene id: 504728:K649_RS13955
uniprot id: M9XC76
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

504728:K649 RS07105
gene id: 504728:K649_RS07105
uniprot id: D3PKC8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

504728:K649 RS00680
gene id: 504728:K649_RS00680
uniprot id: D3PLA3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

504728:K649 RS02020
gene id: 504728:K649_RS02020
uniprot id: A0A806CUT8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

504728:K649 RS08100
gene id: 504728:K649_RS08100
uniprot id: A0A806DP52
names: Similarity
messages: Belongs to the universal stress protein A family.

504728:K649 RS11640
gene id: 504728:K649_RS11640
uniprot id: D3PKQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

504728:K649 RS01550
gene id: 504728:K649_RS01550
uniprot id: D3PM57
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

504728:K649 RS13670
gene id: 504728:K649_RS13670
uniprot id: D3PSU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05760
gene id: 504728:K649_RS05760
uniprot id: D3PR97
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

504728:K649 RS05495
gene id: 504728:K649_RS05495
uniprot id: D3PR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

504728:K649 RS02700
gene id: 504728:K649_RS02700
uniprot id: D3PNJ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS00995
gene id: 504728:K649_RS00995
uniprot id: D3PLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS08960
gene id: 504728:K649_RS08960
uniprot id: D3PNS0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

504728:K649 RS14660
gene id: 504728:K649_RS14660
uniprot id: D3PS96
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

504728:K649 RS02755
gene id: 504728:K649_RS02755
uniprot id: D3PNK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS07055
gene id: 504728:K649_RS07055
uniprot id: D3PKD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

504728:K649 RS10630
gene id: 504728:K649_RS10630
uniprot id: D3PLN8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01340
gene id: 504728:K649_RS01340
uniprot id: D3PM15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

504728:K649 RS11775
gene id: 504728:K649_RS11775
uniprot id: D3PKM7
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS04865
gene id: 504728:K649_RS04865
uniprot id: D3PQS5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

504728:K649 RS01720
gene id: 504728:K649_RS01720
uniprot id: D3PMM5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

504728:K649 RS02785
gene id: 504728:K649_RS02785
uniprot id: A0A806DFG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS00660
gene id: 504728:K649_RS00660
uniprot id: D3PL99
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

504728:K649 RS04495
gene id: 504728:K649_RS04495
uniprot id: D3PQK2
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

504728:K649 RS13275
gene id: 504728:K649_RS13275
uniprot id: D3PT17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS09985
gene id: 504728:K649_RS09985
uniprot id: D3PMF2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

504728:K649 RS00270
gene id: 504728:K649_RS00270
uniprot id: D3PL18
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL34 family.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS09555
gene id: 504728:K649_RS09555
uniprot id: D3PN17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

504728:K649 RS14290
gene id: 504728:K649_RS14290
uniprot id: D3PSG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS08830
gene id: 504728:K649_RS08830
uniprot id: D3PNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

504728:K649 RS03970
gene id: 504728:K649_RS03970
uniprot id: D3PQ08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

504728:K649 RS12155
gene id: 504728:K649_RS12155
uniprot id: D3PTP3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

504728:K649 RS08085
gene id: 504728:K649_RS08085
uniprot id: D3PPM3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

504728:K649 RS04405
gene id: 504728:K649_RS04405
uniprot id: D3PQI4
names: Similarity
messages: Belongs to the manganese catalase family.

504728:K649 RS05055
gene id: 504728:K649_RS05055
uniprot id: D3PQW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

504728:K649 RS13165
gene id: 504728:K649_RS13165
uniprot id: D3PT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

504728:K649 RS09060
gene id: 504728:K649_RS09060
uniprot id: D3PNQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

504728:K649 RS05375
gene id: 504728:K649_RS05375
uniprot id: D3PR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS09185
gene id: 504728:K649_RS09185
uniprot id: D3PN93
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

504728:K649 RS13500
gene id: 504728:K649_RS13500
uniprot id: D3PSX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

504728:K649 RS09250
gene id: 504728:K649_RS09250
uniprot id: D3PN80
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS08345
gene id: 504728:K649_RS08345
uniprot id: M9XDH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

504728:K649 RS05145
gene id: 504728:K649_RS05145
uniprot id: D3PQY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

504728:K649 RS03465
gene id: 504728:K649_RS03465
uniprot id: D3PPC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

504728:K649 RS05510
gene id: 504728:K649_RS05510
uniprot id: A0A806DJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

504728:K649 RS02515
gene id: 504728:K649_RS02515
uniprot id: D3PNG1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

504728:K649 RS02710
gene id: 504728:K649_RS02710
uniprot id: A0A806DHI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

504728:K649 RS13940
gene id: 504728:K649_RS13940
uniprot id: D3PSN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

504728:K649 RS10005
gene id: 504728:K649_RS10005
uniprot id: D3PME8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS13125
gene id: 504728:K649_RS13125
uniprot id: M9XCY0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

504728:K649 RS13600
gene id: 504728:K649_RS13600
uniprot id: D3PSV5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

504728:K649 RS11370
gene id: 504728:K649_RS11370
uniprot id: D3PKV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

504728:K649 RS12260
gene id: 504728:K649_RS12260
uniprot id: D3PTM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

504728:K649 RS13510
gene id: 504728:K649_RS13510
uniprot id: D3PSX2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

504728:K649 RS14940
gene id: 504728:K649_RS14940
uniprot id: D3PS42
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

504728:K649 RS03670
gene id: 504728:K649_RS03670
uniprot id: D3PPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS13560
gene id: 504728:K649_RS13560
uniprot id: D3PSW2
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

504728:K649 RS04410
gene id: 504728:K649_RS04410
uniprot id: D3PQI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

504728:K649 RS08545
gene id: 504728:K649_RS08545
uniprot id: D3PP01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS15290
gene id: 504728:K649_RS15290
uniprot id: D3PRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS12490
gene id: 504728:K649_RS12490
uniprot id: D3PTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

504728:K649 RS09375
gene id: 504728:K649_RS09375
uniprot id: D3PN54
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS00405
gene id: 504728:K649_RS00405
uniprot id: D3PL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS12305
gene id: 504728:K649_RS12305
uniprot id: D3PTL3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS03985
gene id: 504728:K649_RS03985
uniprot id: D3PQ11
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

504728:K649 RS00670
gene id: 504728:K649_RS00670
uniprot id: D3PLA1
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

504728:K649 RS15195
gene id: 504728:K649_RS15195
uniprot id: D3PRZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

504728:K649 RS12470
gene id: 504728:K649_RS12470
uniprot id: D3PTI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05180
gene id: 504728:K649_RS05180
uniprot id: D3PQY8
names: Similarity
messages: Belongs to the phosphopentomutase family.

504728:K649 RS01995
gene id: 504728:K649_RS01995
uniprot id: D3PMS8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

504728:K649 RS10970
gene id: 504728:K649_RS10970
uniprot id: D3PLH0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

504728:K649 RS10230
gene id: 504728:K649_RS10230
uniprot id: D3PMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS01135
gene id: 504728:K649_RS01135
uniprot id: D3PLX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

504728:K649 RS06630
gene id: 504728:K649_RS06630
uniprot id: D3PRR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

504728:K649 RS04460
gene id: 504728:K649_RS04460
uniprot id: D3PQJ5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

504728:K649 RS04375
gene id: 504728:K649_RS04375
uniprot id: D3PQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

504728:K649 RS03425
gene id: 504728:K649_RS03425
uniprot id: D3PPB5
names: Similarity
messages: Belongs to the aldolase LacD family.

504728:K649 RS09425
gene id: 504728:K649_RS09425
uniprot id: D3PN44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

504728:K649 RS01945
gene id: 504728:K649_RS01945
uniprot id: D3PMR8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

504728:K649 RS00620
gene id: 504728:K649_RS00620
uniprot id: D3PL92
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS07940
gene id: 504728:K649_RS07940
uniprot id: D3PPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS07190
gene id: 504728:K649_RS07190
uniprot id: D3PKB2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

504728:K649 RS09710
gene id: 504728:K649_RS09710
uniprot id: D3PMY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09510
gene id: 504728:K649_RS09510
uniprot id: D3PN27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

504728:K649 RS01985
gene id: 504728:K649_RS01985
uniprot id: D3PMS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS03595
gene id: 504728:K649_RS03595
uniprot id: A0A806CQC2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

504728:K649 RS13020
gene id: 504728:K649_RS13020
uniprot id: D3PT69
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

504728:K649 RS07700
gene id: 504728:K649_RS07700
uniprot id: D3PQ75
names: Similarity
messages: Belongs to the PGI/PMI family.

504728:K649 RS10535
gene id: 504728:K649_RS10535
uniprot id: D3PLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

504728:K649 RS03565
gene id: 504728:K649_RS03565
uniprot id: D3PPE3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

504728:K649 RS13890
gene id: 504728:K649_RS13890
uniprot id: D3PSP8
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

504728:K649 RS04570
gene id: 504728:K649_RS04570
uniprot id: D3PQL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

504728:K649 RS04675
gene id: 504728:K649_RS04675
uniprot id: D3PQN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

504728:K649 RS00855
gene id: 504728:K649_RS00855
uniprot id: D3PLD4
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS12365
gene id: 504728:K649_RS12365
uniprot id: D3PTK1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

504728:K649 RS11735
gene id: 504728:K649_RS11735
uniprot id: A0A806DK44
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

504728:K649 RS03150
gene id: 504728:K649_RS03150
uniprot id: D3PP63
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

504728:K649 RS13400
gene id: 504728:K649_RS13400
uniprot id: D3PSZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

504728:K649 RS02000
gene id: 504728:K649_RS02000
uniprot id: D3PMS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

504728:K649 RS11760
gene id: 504728:K649_RS11760
uniprot id: A0A806DLW6
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS04830
gene id: 504728:K649_RS04830
uniprot id: D3PQR7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS05205
gene id: 504728:K649_RS05205
uniprot id: A0A806D846
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

504728:K649 RS05320
gene id: 504728:K649_RS05320
uniprot id: D3PR16
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

504728:K649 RS10430
gene id: 504728:K649_RS10430
uniprot id: D3PM64
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

504728:K649 RS13525
gene id: 504728:K649_RS13525
uniprot id: D3PSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

504728:K649 RS13365
gene id: 504728:K649_RS13365
uniprot id: A0A806CR13
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS07475
gene id: 504728:K649_RS07475
uniprot id: D3PQC0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

504728:K649 RS09120
gene id: 504728:K649_RS09120
uniprot id: D3PNA7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

504728:K649 RS08700
gene id: 504728:K649_RS08700
uniprot id: D3PNX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09930
gene id: 504728:K649_RS09930
uniprot id: D3PMG3
names: Similarity
messages: Belongs to the PstS family.

504728:K649 RS11510
gene id: 504728:K649_RS11510
uniprot id: D3PKS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

504728:K649 RS03855
gene id: 504728:K649_RS03855
uniprot id: D3PPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS10370
gene id: 504728:K649_RS10370
uniprot id: D3PM76
names: Similarity
messages: Belongs to the YoeB family.

504728:K649 RS08720
gene id: 504728:K649_RS08720
uniprot id: D3PNW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

504728:K649 RS05615
gene id: 504728:K649_RS05615
uniprot id: D3PR68
names: Similarity
messages: Belongs to the Fur family.

504728:K649 RS13390
gene id: 504728:K649_RS13390
uniprot id: M9X9R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS06370
gene id: 504728:K649_RS06370
uniprot id: D3PRL8
names: Similarity
messages: Belongs to the SufE family.

504728:K649 RS01870
gene id: 504728:K649_RS01870
uniprot id: D3PMQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS00325
gene id: 504728:K649_RS00325
uniprot id: D3PL29
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS03555
gene id: 504728:K649_RS03555
uniprot id: D3PPE1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

504728:K649 RS11345
gene id: 504728:K649_RS11345
uniprot id: D3PKW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS02940
gene id: 504728:K649_RS02940
uniprot id: D3PNN9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

504728:K649 RS07060
gene id: 504728:K649_RS07060
uniprot id: D3PKD7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

504728:K649 RS08405
gene id: 504728:K649_RS08405
uniprot id: A0A806CX83
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

504728:K649 RS08495
gene id: 504728:K649_RS08495
uniprot id: D3PP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS13575
gene id: 504728:K649_RS13575
uniprot id: D3PSV9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS13025
gene id: 504728:K649_RS13025
uniprot id: D3PT68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

504728:K649 RS09750
gene id: 504728:K649_RS09750
uniprot id: D3PMX9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS11490
gene id: 504728:K649_RS11490
uniprot id: D3PKT3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

504728:K649 RS00335
gene id: 504728:K649_RS00335
uniprot id: D3PL31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

504728:K649 RS14590
gene id: 504728:K649_RS14590
uniprot id: D3PSA9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS09485
gene id: 504728:K649_RS09485
uniprot id: D3PN32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

504728:K649 RS03345
gene id: 504728:K649_RS03345
uniprot id: D3PP99
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

504728:K649 RS04540
gene id: 504728:K649_RS04540
uniprot id: D3PQL1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

504728:K649 RS11920
gene id: 504728:K649_RS11920
uniprot id: D3PTT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

504728:K649 RS07980
gene id: 504728:K649_RS07980
uniprot id: D3PPP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS13460
gene id: 504728:K649_RS13460
uniprot id: D3PSY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS03410
gene id: 504728:K649_RS03410
uniprot id: D3PPB2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS14840
gene id: 504728:K649_RS14840
uniprot id: D3PS60
names: Similarity
messages: Belongs to the peptidase S33 family.

504728:K649 RS13585
gene id: 504728:K649_RS13585
uniprot id: D3PSV7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

504728:K649 RS06515
gene id: 504728:K649_RS06515
uniprot id: D3PRP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

504728:K649 RS04475
gene id: 504728:K649_RS04475
uniprot id: D3PQJ8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

504728:K649 RS14760
gene id: 504728:K649_RS14760
uniprot id: D3PS76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

504728:K649 RS01245
gene id: 504728:K649_RS01245
uniprot id: D3PLZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS12485
gene id: 504728:K649_RS12485
uniprot id: D3PTH7
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS03905
gene id: 504728:K649_RS03905
uniprot id: D3PPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS15295
gene id: 504728:K649_RS15295
uniprot id: D3PRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS10550
gene id: 504728:K649_RS10550
uniprot id: D3PLQ4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

504728:K649 RS07225
gene id: 504728:K649_RS07225
uniprot id: D3PKA5
names: Similarity
messages: Belongs to the pyruvate kinase family.

504728:K649 RS07590
gene id: 504728:K649_RS07590
uniprot id: D3PQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

504728:K649 RS00120
gene id: 504728:K649_RS00120
uniprot id: D3PKK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

504728:K649 RS07705
gene id: 504728:K649_RS07705
uniprot id: D3PQ74
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14355
gene id: 504728:K649_RS14355
uniprot id: D3PSF6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

504728:K649 RS05250
gene id: 504728:K649_RS05250
uniprot id: D3PR02
names: Similarity
messages: Belongs to the disproportionating enzyme family.

504728:K649 RS04960
gene id: 504728:K649_RS04960
uniprot id: D3PQU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

504728:K649 RS12835
gene id: 504728:K649_RS12835
uniprot id: D3PTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

504728:K649 RS04305
gene id: 504728:K649_RS04305
uniprot id: D3PQG4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

504728:K649 RS03140
gene id: 504728:K649_RS03140
uniprot id: D3PP61
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

504728:K649 RS06605
gene id: 504728:K649_RS06605
uniprot id: D3PRR3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

504728:K649 RS10135
gene id: 504728:K649_RS10135
uniprot id: D3PMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

504728:K649 RS12065
gene id: 504728:K649_RS12065
uniprot id: D3PTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS01960
gene id: 504728:K649_RS01960
uniprot id: D3PMS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS13260
gene id: 504728:K649_RS13260
uniprot id: D3PT20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS08490
gene id: 504728:K649_RS08490
uniprot id: D3PP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS12025
gene id: 504728:K649_RS12025
uniprot id: D3PTR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

504728:K649 RS09415
gene id: 504728:K649_RS09415
uniprot id: D3PN46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

504728:K649 RS12170
gene id: 504728:K649_RS12170
uniprot id: D3PTP0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

504728:K649 RS08475
gene id: 504728:K649_RS08475
uniprot id: D3PP15
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

504728:K649 RS03865
gene id: 504728:K649_RS03865
uniprot id: A0A806CNU2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

504728:K649 RS12890
gene id: 504728:K649_RS12890
uniprot id: D3PT96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

504728:K649 RS05140
gene id: 504728:K649_RS05140
uniprot id: D3PQY1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

504728:K649 RS01185
gene id: 504728:K649_RS01185
uniprot id: D3PLY4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

504728:K649 RS00235
gene id: 504728:K649_RS00235
uniprot id: D3PL11
names: Similarity
messages: Belongs to the GARS family.

504728:K649 RS13930
gene id: 504728:K649_RS13930
uniprot id: D3PSP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

504728:K649 RS12455
gene id: 504728:K649_RS12455
uniprot id: D3PTI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

504728:K649 RS01130
gene id: 504728:K649_RS01130
uniprot id: A0A806DGM3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

504728:K649 RS08980
gene id: 504728:K649_RS08980
uniprot id: D3PNR6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

504728:K649 RS14905
gene id: 504728:K649_RS14905
uniprot id: D3PS49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

504728:K649 RS03885
gene id: 504728:K649_RS03885
uniprot id: D3PPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

504728:K649 RS00550
gene id: 504728:K649_RS00550
uniprot id: D3PL78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

504728:K649 RS14065
gene id: 504728:K649_RS14065
uniprot id: D3PSL3
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS04690
gene id: 504728:K649_RS04690
uniprot id: M9XC56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

504728:K649 RS13075
gene id: 504728:K649_RS13075
uniprot id: A0A806CLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS09665
gene id: 504728:K649_RS09665
uniprot id: D3PMZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS01435
gene id: 504728:K649_RS01435
uniprot id: D3PM34
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

504728:K649 RS10655
gene id: 504728:K649_RS10655
uniprot id: D3PLN3
names: Similarity
messages: Belongs to the asp23 family.

504728:K649 RS12460
gene id: 504728:K649_RS12460
uniprot id: D3PTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

504728:K649 RS13615
gene id: 504728:K649_RS13615
uniprot id: D3PSV2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

504728:K649 RS08045
gene id: 504728:K649_RS08045
uniprot id: D3PPN1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

504728:K649 RS01025
gene id: 504728:K649_RS01025
uniprot id: A0A806DGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS14350
gene id: 504728:K649_RS14350
uniprot id: D3PSF7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

504728:K649 RS01375
gene id: 504728:K649_RS01375
uniprot id: D3PM22
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

504728:K649 RS13975
gene id: 504728:K649_RS13975
uniprot id: D3PSN1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

504728:K649 RS08300
gene id: 504728:K649_RS08300
uniprot id: D3PPH8
names: Similarity
messages: Belongs to the NAPRTase family.

504728:K649 RS03915
gene id: 504728:K649_RS03915
uniprot id: D3PPZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

504728:K649 RS12225
gene id: 504728:K649_RS12225
uniprot id: D3PTM9
names: Similarity
messages: Belongs to the FGGY kinase family.

504728:K649 RS06550
gene id: 504728:K649_RS06550
uniprot id: D3PRQ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS04695
gene id: 504728:K649_RS04695
uniprot id: D3PQP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

504728:K649 RS05230
gene id: 504728:K649_RS05230
uniprot id: A0A806CS13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

504728:K649 RS12275
gene id: 504728:K649_RS12275
uniprot id: D3PTL9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS08780
gene id: 504728:K649_RS08780
uniprot id: D3PNV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

504728:K649 RS08150
gene id: 504728:K649_RS08150
uniprot id: D3PPK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

504728:K649 RS14060
gene id: 504728:K649_RS14060
uniprot id: D3PSL4
names: Similarity
messages: Belongs to the acylphosphatase family.

504728:K649 RS01000
gene id: 504728:K649_RS01000
uniprot id: D3PLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS15060
gene id: 504728:K649_RS15060
uniprot id: D3PS18
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

504728:K649 RS13085
gene id: 504728:K649_RS13085
uniprot id: D3PT55
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

504728:K649 RS04685
gene id: 504728:K649_RS04685
uniprot id: D3PQN9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

504728:K649 RS11530
gene id: 504728:K649_RS11530
uniprot id: D3PKS5
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

504728:K649 RS04085
gene id: 504728:K649_RS04085
uniprot id: D3PQ31
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS05635
gene id: 504728:K649_RS05635
uniprot id: A0A806DHQ5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS09285
gene id: 504728:K649_RS09285
uniprot id: A0A806DLH9
names: Similarity
messages: Belongs to the leucine-binding protein family.

504728:K649 RS01610
gene id: 504728:K649_RS01610
uniprot id: D3PMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

504728:K649 RS12045
gene id: 504728:K649_RS12045
uniprot id: D3PTR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

504728:K649 RS12090
gene id: 504728:K649_RS12090
uniprot id: D3PTQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS13860
gene id: 504728:K649_RS13860
uniprot id: D3PSQ4
names: Similarity
messages: Belongs to the citrate synthase family.

504728:K649 RS13705
gene id: 504728:K649_RS13705
uniprot id: A0A806CSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

504728:K649 RS14555
gene id: 504728:K649_RS14555
uniprot id: D3PSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

504728:K649 RS06290
gene id: 504728:K649_RS06290
uniprot id: D3PRK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

504728:K649 RS09835
gene id: 504728:K649_RS09835
uniprot id: D3PMI3
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09805
gene id: 504728:K649_RS09805
uniprot id: D3PMI9
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

504728:K649 RS08825
gene id: 504728:K649_RS08825
uniprot id: D3PNU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

504728:K649 RS04850
gene id: 504728:K649_RS04850
uniprot id: D3PQS2
names: Similarity
messages: Belongs to the GSP E family.

504728:K649 RS13395
gene id: 504728:K649_RS13395
uniprot id: D3PSZ3
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS10910
gene id: 504728:K649_RS10910
uniprot id: D3PLI2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

504728:K649 RS06280
gene id: 504728:K649_RS06280
uniprot id: M9X5N5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

504728:K649 RS00410
gene id: 504728:K649_RS00410
uniprot id: D3PL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS03000
gene id: 504728:K649_RS03000
uniprot id: M9X3N1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

504728:K649 RS07180
gene id: 504728:K649_RS07180
uniprot id: D3PKB4
names: Similarity
messages: Belongs to the PspA/IM30 family.

504728:K649 RS14490
gene id: 504728:K649_RS14490
uniprot id: A0A806CQI6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

504728:K649 RS12325
gene id: 504728:K649_RS12325
uniprot id: D3PTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

504728:K649 RS04680
gene id: 504728:K649_RS04680
uniprot id: D3PQN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

504728:K649 RS04870
gene id: 504728:K649_RS04870
uniprot id: D3PQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS06040
gene id: 504728:K649_RS06040
uniprot id: M9X8S4
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS04285
gene id: 504728:K649_RS04285
uniprot id: D3PQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS08955
gene id: 504728:K649_RS08955
uniprot id: D3PNS1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

504728:K649 RS12020
gene id: 504728:K649_RS12020
uniprot id: D3PTR9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

504728:K649 RS04390
gene id: 504728:K649_RS04390
uniprot id: D3PQI1
names: Similarity
messages: Belongs to the GSP E family.

504728:K649 RS13215
gene id: 504728:K649_RS13215
uniprot id: D3PT29
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

504728:K649 RS01915
gene id: 504728:K649_RS01915
uniprot id: A0A806CPM6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

504728:K649 RS11375
gene id: 504728:K649_RS11375
uniprot id: D3PKV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

504728:K649 RS07830
gene id: 504728:K649_RS07830
uniprot id: D3PPS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

504728:K649 RS02915
gene id: 504728:K649_RS02915
uniprot id: D3PNN4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS14545
gene id: 504728:K649_RS14545
uniprot id: D3PSB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS10590
gene id: 504728:K649_RS10590
uniprot id: D3PLP6
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09575
gene id: 504728:K649_RS09575
uniprot id: D3PN13
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

504728:K649 RS14360
gene id: 504728:K649_RS14360
uniprot id: A0A806CXU1
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13540
gene id: 504728:K649_RS13540
uniprot id: D3PSW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

504728:K649 RS01490
gene id: 504728:K649_RS01490
uniprot id: D3PM45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

504728:K649 RS08335
gene id: 504728:K649_RS08335
uniprot id: D3PPH1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

504728:K649 RS01790
gene id: 504728:K649_RS01790
uniprot id: M9X4V9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS11595
gene id: 504728:K649_RS11595
uniprot id: M9XFF2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

504728:K649 RS15125
gene id: 504728:K649_RS15125
uniprot id: D3PS05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

504728:K649 RS11280
gene id: 504728:K649_RS11280
uniprot id: A0A806CVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS09080
gene id: 504728:K649_RS09080
uniprot id: A0A806CT77
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

504728:K649 RS11615
gene id: 504728:K649_RS11615
uniprot id: D3PKQ9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

504728:K649 RS09435
gene id: 504728:K649_RS09435
uniprot id: D3PN42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

504728:K649 RS13170
gene id: 504728:K649_RS13170
uniprot id: D3PT38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

504728:K649 RS09470
gene id: 504728:K649_RS09470
uniprot id: D3PN35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS03445
gene id: 504728:K649_RS03445
uniprot id: D3PPB9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS03910
gene id: 504728:K649_RS03910
uniprot id: D3PPZ5
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

504728:K649 RS06615
gene id: 504728:K649_RS06615
uniprot id: D3PRR5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

504728:K649 RS10385
gene id: 504728:K649_RS10385
uniprot id: D3PM73
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

504728:K649 RS10665
gene id: 504728:K649_RS10665
uniprot id: D3PLN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

504728:K649 RS02945
gene id: 504728:K649_RS02945
uniprot id: D3PNP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

504728:K649 RS08930
gene id: 504728:K649_RS08930
uniprot id: D3PNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.
messages: Cytoplasm

504728:K649 RS10080
gene id: 504728:K649_RS10080
uniprot id: M9XB82
names: Function
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class III subfamily.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert both AMP to ADP and ADP to ATP. Can also use GMP, CMP, UMP, GDP, CDP and UDP.

504728:K649 RS15205
gene id: 504728:K649_RS15205
uniprot id: A0A806CQ76
names: Similarity
messages: Belongs to the BMP lipoprotein family.

504728:K649 RS10795
gene id: 504728:K649_RS10795
uniprot id: A0A806DBY8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS05200
gene id: 504728:K649_RS05200
uniprot id: D3PQZ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS09180
gene id: 504728:K649_RS09180
uniprot id: A0A806CWV8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

504728:K649 RS09595
gene id: 504728:K649_RS09595
uniprot id: D3PN10
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

504728:K649 RS04560
gene id: 504728:K649_RS04560
uniprot id: D3PQL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

504728:K649 RS00800
gene id: 504728:K649_RS00800
uniprot id: D3PLC5
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14810
gene id: 504728:K649_RS14810
uniprot id: D3PS66
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

504728:K649 RS09570
gene id: 504728:K649_RS09570
uniprot id: D3PN14
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

504728:K649 RS09500
gene id: 504728:K649_RS09500
uniprot id: D3PN29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

504728:K649 RS12960
gene id: 504728:K649_RS12960
uniprot id: D3PT81
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS11465
gene id: 504728:K649_RS11465
uniprot id: D3PKT8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS06440
gene id: 504728:K649_RS06440
uniprot id: D3PRN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS14830
gene id: 504728:K649_RS14830
uniprot id: D3PS62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

504728:K649 RS06625
gene id: 504728:K649_RS06625
uniprot id: D3PRR7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

504728:K649 RS04525
gene id: 504728:K649_RS04525
uniprot id: D3PQK8
names: Similarity
messages: Belongs to the aspartokinase family.

504728:K649 RS10290
gene id: 504728:K649_RS10290
uniprot id: D3PM91
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS12850
gene id: 504728:K649_RS12850
uniprot id: D3PTA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

504728:K649 RS02990
gene id: 504728:K649_RS02990
uniprot id: A0A806CJ94
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

504728:K649 RS04490
gene id: 504728:K649_RS04490
uniprot id: D3PQK1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

504728:K649 RS11110
gene id: 504728:K649_RS11110
uniprot id: D3PLE3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

504728:K649 RS12240
gene id: 504728:K649_RS12240
uniprot id: D3PTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

504728:K649 RS09475
gene id: 504728:K649_RS09475
uniprot id: A0A806CWQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

504728:K649 RS01200
gene id: 504728:K649_RS01200
uniprot id: D3PLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS11840
gene id: 504728:K649_RS11840
uniprot id: A0A806CZ57
names: Similarity
messages: Belongs to the ComB family.

504728:K649 RS08330
gene id: 504728:K649_RS08330
uniprot id: M9X949
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS12885
gene id: 504728:K649_RS12885
uniprot id: D3PT97
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

504728:K649 RS08365
gene id: 504728:K649_RS08365
uniprot id: D3PPG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05210
gene id: 504728:K649_RS05210
uniprot id: D3PQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS07870
gene id: 504728:K649_RS07870
uniprot id: D3PPR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS12475
gene id: 504728:K649_RS12475
uniprot id: A0A806CRI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

504728:K649 RS08140
gene id: 504728:K649_RS08140
uniprot id: D3PPL1
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS03475
gene id: 504728:K649_RS03475
uniprot id: D3PPC5
names: Cofactor
messages: Can also use Mn(2+) ion.

504728:K649 RS14945
gene id: 504728:K649_RS14945
uniprot id: D3PS41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

504728:K649 RS12130
gene id: 504728:K649_RS12130
uniprot id: D3PTP7
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS15160
gene id: 504728:K649_RS15160
uniprot id: M9XE38
names: Similarity
messages: Belongs to the Fur family.

504728:K649 RS06470
gene id: 504728:K649_RS06470
uniprot id: D3PRN7
names: Similarity
messages: Belongs to the peptidase M24B family.

504728:K649 RS02800
gene id: 504728:K649_RS02800
uniprot id: D3PNL1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

504728:K649 RS05770
gene id: 504728:K649_RS05770
uniprot id: D3PR99
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

504728:K649 RS04995
gene id: 504728:K649_RS04995
uniprot id: D3PQV1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

504728:K649 RS11560
gene id: 504728:K649_RS11560
uniprot id: D3PKR9
names: Similarity
messages: Belongs to the peptidase M16 family.

504728:K649 RS14450
gene id: 504728:K649_RS14450
uniprot id: D3PSD7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

504728:K649 RS00290
gene id: 504728:K649_RS00290
uniprot id: D3PL22
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS02910
gene id: 504728:K649_RS02910
uniprot id: D3PNN3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS12210
gene id: 504728:K649_RS12210
uniprot id: D3PTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS09505
gene id: 504728:K649_RS09505
uniprot id: D3PN28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

504728:K649 RS10925
gene id: 504728:K649_RS10925
uniprot id: D3PLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

504728:K649 RS01565
gene id: 504728:K649_RS01565
uniprot id: D3PM60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

504728:K649 RS03360
gene id: 504728:K649_RS03360
uniprot id: D3PPA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

504728:K649 RS14140
gene id: 504728:K649_RS14140
uniprot id: D3PSJ8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

504728:K649 RS12480
gene id: 504728:K649_RS12480
uniprot id: D3PTH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS12925
gene id: 504728:K649_RS12925
uniprot id: D3PT88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

504728:K649 RS08820
gene id: 504728:K649_RS08820
uniprot id: D3PNU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

504728:K649 RS02385
gene id: 504728:K649_RS02385
uniprot id: A0A806CV03
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

504728:K649 RS15315
gene id: 504728:K649_RS15315
uniprot id: A0A806CSV2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS08290
gene id: 504728:K649_RS08290
uniprot id: A0A806DP18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

504728:K649 RS07230
gene id: 504728:K649_RS07230
uniprot id: D3PKA4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

504728:K649 RS08945
gene id: 504728:K649_RS08945
uniprot id: D3PNS3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS04355
gene id: 504728:K649_RS04355
uniprot id: D3PQH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS02705
gene id: 504728:K649_RS02705
uniprot id: D3PNJ2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

504728:K649 RS10155
gene id: 504728:K649_RS10155
uniprot id: D3PMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

504728:K649 RS13000
gene id: 504728:K649_RS13000
uniprot id: D3PT73
names: Similarity
messages: Belongs to the phosphohexose mutase family.

504728:K649 RS08940
gene id: 504728:K649_RS08940
uniprot id: D3PNS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05170
gene id: 504728:K649_RS05170
uniprot id: D3PQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

504728:K649 RS11095
gene id: 504728:K649_RS11095
uniprot id: D3PLE6
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

504728:K649 RS13240
gene id: 504728:K649_RS13240
uniprot id: D3PT24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

504728:K649 RS04880
gene id: 504728:K649_RS04880
uniprot id: A0A806CRV4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

504728:K649 RS04910
gene id: 504728:K649_RS04910
uniprot id: A0A806CQY7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

504728:K649 RS00915
gene id: 504728:K649_RS00915
uniprot id: D3PLT1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS08765
gene id: 504728:K649_RS08765
uniprot id: D3PNV9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

504728:K649 RS07295
gene id: 504728:K649_RS07295
uniprot id: D3PQF3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS09055
gene id: 504728:K649_RS09055
uniprot id: D3PNQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

504728:K649 RS13715
gene id: 504728:K649_RS13715
uniprot id: M9X9W4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

504728:K649 RS03960
gene id: 504728:K649_RS03960
uniprot id: D3PQ06
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01230
gene id: 504728:K649_RS01230
uniprot id: D3PLZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

504728:K649 RS11360
gene id: 504728:K649_RS11360
uniprot id: D3PKV9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

504728:K649 RS10330
gene id: 504728:K649_RS10330
uniprot id: D3PM83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

504728:K649 RS07530
gene id: 504728:K649_RS07530
uniprot id: D3PQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

504728:K649 RS06895
gene id: 504728:K649_RS06895
uniprot id: D3PKH0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

504728:K649 RS04815
gene id: 504728:K649_RS04815
uniprot id: A0A806CQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS13950
gene id: 504728:K649_RS13950
uniprot id: D3PSN6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

504728:K649 RS10040
gene id: 504728:K649_RS10040
uniprot id: D3PME1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

504728:K649 RS01390
gene id: 504728:K649_RS01390
uniprot id: D3PM25
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

504728:K649 RS07010
gene id: 504728:K649_RS07010
uniprot id: D3PKE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

504728:K649 RS08320
gene id: 504728:K649_RS08320
uniprot id: D3PPH4
names: Similarity
messages: Belongs to the DinB family.

504728:K649 RS08380
gene id: 504728:K649_RS08380
uniprot id: D3PPG2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

504728:K649 RS02690
gene id: 504728:K649_RS02690
uniprot id: D3PNI9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

504728:K649 RS08885
gene id: 504728:K649_RS08885
uniprot id: A0A806CND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS04535
gene id: 504728:K649_RS04535
uniprot id: D3PQL0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

504728:K649 RS01080
gene id: 504728:K649_RS01080
uniprot id: D3PLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

504728:K649 RS00870
gene id: 504728:K649_RS00870
uniprot id: D3PLD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

504728:K649 RS02610
gene id: 504728:K649_RS02610
uniprot id: D3PNH6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

504728:K649 RS00360
gene id: 504728:K649_RS00360
uniprot id: A0A806CMF8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS05695
gene id: 504728:K649_RS05695
uniprot id: D3PR84
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

504728:K649 RS04015
gene id: 504728:K649_RS04015
uniprot id: D3PQ17
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

504728:K649 RS09440
gene id: 504728:K649_RS09440
uniprot id: D3PN41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

504728:K649 RS12980
gene id: 504728:K649_RS12980
uniprot id: D3PT77
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

504728:K649 RS00765
gene id: 504728:K649_RS00765
uniprot id: D3PLB9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

504728:K649 RS03490
gene id: 504728:K649_RS03490
uniprot id: D3PPC8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

504728:K649 RS12135
gene id: 504728:K649_RS12135
uniprot id: D3PTP6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

504728:K649 RS03370
gene id: 504728:K649_RS03370
uniprot id: D3PPA4
names: Similarity
messages: Belongs to the CinA family.

504728:K649 RS07795
gene id: 504728:K649_RS07795
uniprot id: D3PPS9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

504728:K649 RS14955
gene id: 504728:K649_RS14955
uniprot id: D3PS39
names: Similarity
messages: Belongs to the peptidase M29 family.

504728:K649 RS01285
gene id: 504728:K649_RS01285
uniprot id: D3PM04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

504728:K649 RS11590
gene id: 504728:K649_RS11590
uniprot id: D3PKR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

504728:K649 RS13665
gene id: 504728:K649_RS13665
uniprot id: D3PSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

504728:K649 RS13070
gene id: 504728:K649_RS13070
uniprot id: D3PT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS09545
gene id: 504728:K649_RS09545
uniprot id: D3PN20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

504728:K649 RS10060
gene id: 504728:K649_RS10060
uniprot id: D3PMD7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

504728:K649 RS13375
gene id: 504728:K649_RS13375
uniprot id: D3PSZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

504728:K649 RS08810
gene id: 504728:K649_RS08810
uniprot id: D3PNV0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

504728:K649 RS10870
gene id: 504728:K649_RS10870
uniprot id: D3PLJ0
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS00465
gene id: 504728:K649_RS00465
uniprot id: M9X255
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS04470
gene id: 504728:K649_RS04470
uniprot id: D3PQJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

504728:K649 RS12860
gene id: 504728:K649_RS12860
uniprot id: D3PTA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS00430
gene id: 504728:K649_RS00430
uniprot id: A0A806CP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS03170
gene id: 504728:K649_RS03170
uniprot id: D3PP67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

504728:K649 RS09350
gene id: 504728:K649_RS09350
uniprot id: D3PN59
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

504728:K649 RS13555
gene id: 504728:K649_RS13555
uniprot id: D3PSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

504728:K649 RS12140
gene id: 504728:K649_RS12140
uniprot id: D3PTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

504728:K649 RS06505
gene id: 504728:K649_RS06505
uniprot id: D3PRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

504728:K649 RS06405
gene id: 504728:K649_RS06405
uniprot id: D3PRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

504728:K649 RS00350
gene id: 504728:K649_RS00350
uniprot id: A0A806CI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

504728:K649 RS02735
gene id: 504728:K649_RS02735
uniprot id: D3PNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

504728:K649 RS04640
gene id: 504728:K649_RS04640
uniprot id: D3PQN1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

504728:K649 RS04350
gene id: 504728:K649_RS04350
uniprot id: D3PQH3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

504728:K649 RS12910
gene id: 504728:K649_RS12910
uniprot id: D3PT91
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

504728:K649 RS12285
gene id: 504728:K649_RS12285
uniprot id: D3PTL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

504728:K649 RS02355
gene id: 504728:K649_RS02355
uniprot id: A0A806CN98
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

504728:K649 RS05475
gene id: 504728:K649_RS05475
uniprot id: A0A806CRA5
names: Similarity
messages: Belongs to the MreC family.

504728:K649 RS15030
gene id: 504728:K649_RS15030
uniprot id: A0A806CS38
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

504728:K649 RS08710
gene id: 504728:K649_RS08710
uniprot id: D3PNW9
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

504728:K649 RS08595
gene id: 504728:K649_RS08595
uniprot id: M9X999
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

504728:K649 RS08610
gene id: 504728:K649_RS08610
uniprot id: D3PNY8
names: Similarity
messages: Belongs to the asp23 family.

504728:K649 RS14055
gene id: 504728:K649_RS14055
uniprot id: D3PSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

504728:K649 RS00180
gene id: 504728:K649_RS00180
uniprot id: D3PKL7
names: Similarity
messages: Belongs to the GSP E family.

504728:K649 RS06715
gene id: 504728:K649_RS06715
uniprot id: D3PRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

504728:K649 RS11935
gene id: 504728:K649_RS11935
uniprot id: D3PTT6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

504728:K649 RS07745
gene id: 504728:K649_RS07745
uniprot id: D3PPT5
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS09550
gene id: 504728:K649_RS09550
uniprot id: D3PN19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

504728:K649 RS06680
gene id: 504728:K649_RS06680
uniprot id: D3PRS8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

504728:K649 RS13580
gene id: 504728:K649_RS13580
uniprot id: D3PSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

504728:K649 RS03500
gene id: 504728:K649_RS03500
uniprot id: D3PPD0
names: Similarity
messages: Belongs to the glutamine synthetase family.

504728:K649 RS14610
gene id: 504728:K649_RS14610
uniprot id: A0A806CXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

504728:K649 RS00445
gene id: 504728:K649_RS00445
uniprot id: D3PL54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS10820
gene id: 504728:K649_RS10820
uniprot id: D3PLK0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

504728:K649 RS08355
gene id: 504728:K649_RS08355
uniprot id: D3PPG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

504728:K649 RS09030
gene id: 504728:K649_RS09030
uniprot id: A0A806CT86
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

504728:K649 RS13475
gene id: 504728:K649_RS13475
uniprot id: A0A806CQZ5
names: Similarity
messages: Belongs to the glutamate synthase family.

504728:K649 RS11535
gene id: 504728:K649_RS11535
uniprot id: D3PKS4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

504728:K649 RS01040
gene id: 504728:K649_RS01040
uniprot id: D3PLV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

504728:K649 RS06930
gene id: 504728:K649_RS06930
uniprot id: A0A806DFW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

504728:K649 RS05035
gene id: 504728:K649_RS05035
uniprot id: D3PQV9
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS00925
gene id: 504728:K649_RS00925
uniprot id: D3PLT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

504728:K649 RS11070
gene id: 504728:K649_RS11070
uniprot id: D3PLF0
names: Subcellular Location Annotation
messages: Cytoplasm

504728:K649 RS07160
gene id: 504728:K649_RS07160
uniprot id: A0A806DDA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

504728:K649 RS06350
gene id: 504728:K649_RS06350
uniprot id: D3PRL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

504728:K649 RS09990
gene id: 504728:K649_RS09990
uniprot id: D3PMF1
names: Similarity
messages: Belongs to the histone deacetylase family.

504728:K649 RS00705
gene id: 504728:K649_RS00705
uniprot id: D3PLA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

504728:K649 RS13160
gene id: 504728:K649_RS13160
uniprot id: D3PT40
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01030
gene id: 504728:K649_RS01030
uniprot id: A0A806DEW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

504728:K649 RS05425
gene id: 504728:K649_RS05425
uniprot id: D3PR34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

504728:K649 RS07565
gene id: 504728:K649_RS07565
uniprot id: D3PQA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS14600
gene id: 504728:K649_RS14600
uniprot id: D3PSA7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

504728:K649 RS01855
gene id: 504728:K649_RS01855
uniprot id: M9X2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

504728:K649 RS08600
gene id: 504728:K649_RS08600
uniprot id: D3PNZ0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

504728:K649 RS14245
gene id: 504728:K649_RS14245
uniprot id: D3PSH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

504728:K649 RS05560
gene id: 504728:K649_RS05560
uniprot id: D3PR61
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

504728:K649 RS01360
gene id: 504728:K649_RS01360
uniprot id: A0A806CIM0
names: Similarity
messages: Belongs to the asparagine synthetase family.

504728:K649 RS10605
gene id: 504728:K649_RS10605
uniprot id: D3PLP3
names: Similarity
messages: Belongs to the peptidase U62 family.

504728:K649 RS06450
gene id: 504728:K649_RS06450
uniprot id: D3PRN3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

504728:K649 RS14425
gene id: 504728:K649_RS14425
uniprot id: D3PSE2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

504728:K649 RS10780
gene id: 504728:K649_RS10780
uniprot id: D3PLK8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

504728:K649 RS01885
gene id: 504728:K649_RS01885
uniprot id: D3PMQ6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

504728:K649 RS07850
gene id: 504728:K649_RS07850
uniprot id: D3PPR8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

504728:K649 RS07110
gene id: 504728:K649_RS07110
uniprot id: D3PKC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

504728:K649 RS03420
gene id: 504728:K649_RS03420
uniprot id: D3PPB4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

504728:K649 RS13945
gene id: 504728:K649_RS13945
uniprot id: D3PSN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

504728:K649 RS00595
gene id: 504728:K649_RS00595
uniprot id: D3PL87
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

504728:K649 RS04590
gene id: 504728:K649_RS04590
uniprot id: D3PQM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

504728:K649 RS13330
gene id: 504728:K649_RS13330
uniprot id: D3PT07
names: Similarity
messages: Belongs to the peptidase M29 family.

504728:K649 RS12080
gene id: 504728:K649_RS12080
uniprot id: D3PTQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

504728:K649 RS10920
gene id: 504728:K649_RS10920
uniprot id: D3PLI0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

504728:K649 RS09345
gene id: 504728:K649_RS09345
uniprot id: D3PN60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

504728:K649 RS00495
gene id: 504728:K649_RS00495
uniprot id: D3PL64
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

504728:K649 RS00975
gene id: 504728:K649_RS00975
uniprot id: D3PLU3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

504728:K649 RS11315
gene id: 504728:K649_RS11315
uniprot id: D3PKW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

504728:K649 RS05130
gene id: 504728:K649_RS05130
uniprot id: D3PQX9
names: Similarity
messages: Belongs to the arginase family.

504728:K649 RS02960
gene id: 504728:K649_RS02960
uniprot id: D3PNP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

504728:K649 RS02010
gene id: 504728:K649_RS02010
uniprot id: D3PMT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

504728:K649 RS14770
gene id: 504728:K649_RS14770
uniprot id: D3PS74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

504728:K649 RS05380
gene id: 504728:K649_RS05380
uniprot id: D3PR25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS01865
gene id: 504728:K649_RS01865
uniprot id: D3PMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

504728:K649 RS10015
gene id: 504728:K649_RS10015
uniprot id: D3PME6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

504728:K649 RS00240
gene id: 504728:K649_RS00240
uniprot id: D3PL12
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

504728:K649 RS03355
gene id: 504728:K649_RS03355
uniprot id: A0A806CJE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

504728:K649 RS09905
gene id: 504728:K649_RS09905
uniprot id: D3PMG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

504728:K649 RS10260
gene id: 504728:K649_RS10260
uniprot id: D3PM97
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

504728:K649 RS08160
gene id: 504728:K649_RS08160
uniprot id: D3PPK6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

504728:K649 RS10170
gene id: 504728:K649_RS10170
uniprot id: D3PMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

504728:K649 RS03505
gene id: 504728:K649_RS03505
uniprot id: D3PPD1
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS14085
gene id: 504728:K649_RS14085
uniprot id: D3PSK9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

504728:K649 RS14805
gene id: 504728:K649_RS14805
uniprot id: D3PS67
names: Similarity
messages: Belongs to the DinB family.

504728:K649 RS08155
gene id: 504728:K649_RS08155
uniprot id: D3PPK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

504728:K649 RS13565
gene id: 504728:K649_RS13565
uniprot id: A0A806DKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

504728:K649 RS09275
gene id: 504728:K649_RS09275
uniprot id: D3PN75
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS11275
gene id: 504728:K649_RS11275
uniprot id: D3PKX8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

504728:K649 RS13185
gene id: 504728:K649_RS13185
uniprot id: D3PT35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS08095
gene id: 504728:K649_RS08095
uniprot id: D3PPM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

504728:K649 RS13105
gene id: 504728:K649_RS13105
uniprot id: D3PT51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

504728:K649 RS00160
gene id: 504728:K649_RS00160
uniprot id: D3PKL2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

504728:K649 RS02680
gene id: 504728:K649_RS02680
uniprot id: D3PNI8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

504728:K649 RS11455
gene id: 504728:K649_RS11455
uniprot id: D3PKU0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

504728:K649 RS05570
gene id: 504728:K649_RS05570
uniprot id: D3PR63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

504728:K649 RS11100
gene id: 504728:K649_RS11100
uniprot id: D3PLE5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

504728:K649 RS08650
gene id: 504728:K649_RS08650
uniprot id: M9X6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

504728:K649 RS11145
gene id: 504728:K649_RS11145
uniprot id: A0A806CZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS14960
gene id: 504728:K649_RS14960
uniprot id: D3PS38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

504728:K649 RS09235
gene id: 504728:K649_RS09235
uniprot id: A0A806CN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

504728:K649 RS06195
gene id: 504728:K649_RS06195
uniprot id: A0A806D926
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS14030
gene id: 504728:K649_RS14030
uniprot id: A0A806CNC5
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS06670
gene id: 504728:K649_RS06670
uniprot id: M9XCF8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

504728:K649 RS12270
gene id: 504728:K649_RS12270
uniprot id: D3PTM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

504728:K649 RS09645
gene id: 504728:K649_RS09645
uniprot id: A0A806CVA2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

504728:K649 RS14835
gene id: 504728:K649_RS14835
uniprot id: D3PS61
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

504728:K649 RS02880
gene id: 504728:K649_RS02880
uniprot id: D3PNM7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS03280
gene id: 504728:K649_RS03280
uniprot id: D3PP87
names: Similarity
messages: Belongs to the UbiD family.

504728:K649 RS05420
gene id: 504728:K649_RS05420
uniprot id: D3PR33
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

504728:K649 RS15260
gene id: 504728:K649_RS15260
uniprot id: D3PRX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

504728:K649 RS05565
gene id: 504728:K649_RS05565
uniprot id: D3PR62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

504728:K649 RS09075
gene id: 504728:K649_RS09075
uniprot id: D3PNP8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

504728:K649 RS03880
gene id: 504728:K649_RS03880
uniprot id: D3PPY9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

504728:K649 RS01920
gene id: 504728:K649_RS01920
uniprot id: A0A806CUS0
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS01370
gene id: 504728:K649_RS01370
uniprot id: D3PM21
names: Similarity
messages: Belongs to the asparagine synthetase family.

504728:K649 RS12315
gene id: 504728:K649_RS12315
uniprot id: D3PTL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

504728:K649 RS12095
gene id: 504728:K649_RS12095
uniprot id: D3PTQ4
names: Similarity
messages: Belongs to the DprA/Smf family.

504728:K649 RS13410
gene id: 504728:K649_RS13410
uniprot id: A0A806CR05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

504728:K649 RS14335
gene id: 504728:K649_RS14335
uniprot id: D3PSG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS05550
gene id: 504728:K649_RS05550
uniprot id: D3PR59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

504728:K649 RS03675
gene id: 504728:K649_RS03675
uniprot id: D3PPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

504728:K649 RS06430
gene id: 504728:K649_RS06430
uniprot id: A0A806CPZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

504728:K649 RS06545
gene id: 504728:K649_RS06545
uniprot id: D3PRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

504728:K649 RS15185
gene id: 504728:K649_RS15185
uniprot id: D3PRZ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

504728:K649 RS07015
gene id: 504728:K649_RS07015
uniprot id: D3PKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

504728:K649 RS05045
gene id: 504728:K649_RS05045
uniprot id: D3PQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

504728:K649 RS05545
gene id: 504728:K649_RS05545
uniprot id: D3PR58
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS13110
gene id: 504728:K649_RS13110
uniprot id: A0A806CNP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

504728:K649 RS04190
gene id: 504728:K649_RS04190
uniprot id: A0A806DIF9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

504728:K649 RS08935
gene id: 504728:K649_RS08935
uniprot id: D3PNS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

504728:K649 RS15155
gene id: 504728:K649_RS15155
uniprot id: A0A806CQ84
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

504728:K649 RS07390
gene id: 504728:K649_RS07390
uniprot id: D3PQD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

504728:K649 RS12525
gene id: 504728:K649_RS12525
uniprot id: D3PTG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

504728:K649 RS15025
gene id: 504728:K649_RS15025
uniprot id: D3PS25
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

504728:K649 RS07805
gene id: 504728:K649_RS07805
uniprot id: D3PPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

504728:K649 RS04185
gene id: 504728:K649_RS04185
uniprot id: D3PQ47
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

504728:K649 RS15265
gene id: 504728:K649_RS15265
uniprot id: D3PRX8
names: Subcellular Location Annotation
messages: Membrane

504728:K649 RS12830
gene id: 504728:K649_RS12830
uniprot id: D3PTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

504728:K649 RS04935
gene id: 504728:K649_RS04935
uniprot id: D3PQT9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS11220
gene id: 504728:K649_RS11220
uniprot id: D3PKY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

504728:K649 RS09290
gene id: 504728:K649_RS09290
uniprot id: D3PN71
names: Similarity
messages: Belongs to the glutamine synthetase family.

504728:K649 RS04940
gene id: 504728:K649_RS04940
uniprot id: D3PQU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

504728:K649 RS09390
gene id: 504728:K649_RS09390
uniprot id: D3PN51
names: Similarity
messages: Belongs to the Nudix hydrolase family.

504728:K649 RS03625
gene id: 504728:K649_RS03625
uniprot id: A0A806CLD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

504728:K649 RS13965
gene id: 504728:K649_RS13965
uniprot id: D3PSN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

504728:K649 RS04455
gene id: 504728:K649_RS04455
uniprot id: D3PQJ4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

504728:K649 RS07965
gene id: 504728:K649_RS07965
uniprot id: D3PPP6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

504728:K649 RS04930
gene id: 504728:K649_RS04930
uniprot id: A0A806CRW4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

504728:K649 RS14315
gene id: 504728:K649_RS14315
uniprot id: D3PSG4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.