491952:MAR181 RS04980
gene id: 491952:MAR181_RS04980
uniprot id: F6CTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

491952:MAR181 RS00130
gene id: 491952:MAR181_RS00130
uniprot id: F6CYW7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS02380
gene id: 491952:MAR181_RS02380
uniprot id: F6CZ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

491952:MAR181 RS09595
gene id: 491952:MAR181_RS09595
uniprot id: F6CRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

491952:MAR181 RS17570
gene id: 491952:MAR181_RS17570
uniprot id: F6CV54
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

491952:MAR181 RS00015
gene id: 491952:MAR181_RS00015
uniprot id: F6CYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

491952:MAR181 RS14380
gene id: 491952:MAR181_RS14380
uniprot id: F6D031
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

491952:MAR181 RS05830
gene id: 491952:MAR181_RS05830
uniprot id: F6CV90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS11395
gene id: 491952:MAR181_RS11395
uniprot id: F6CUU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

491952:MAR181 RS17640
gene id: 491952:MAR181_RS17640
uniprot id: F6CV68
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

491952:MAR181 RS11010
gene id: 491952:MAR181_RS11010
uniprot id: F6CU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS14475
gene id: 491952:MAR181_RS14475
uniprot id: F6D050
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

491952:MAR181 RS17385
gene id: 491952:MAR181_RS17385
uniprot id: F6CV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

491952:MAR181 RS07755
gene id: 491952:MAR181_RS07755
uniprot id: F6CYF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

491952:MAR181 RS02260
gene id: 491952:MAR181_RS02260
uniprot id: F6CZ63
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

491952:MAR181 RS12175
gene id: 491952:MAR181_RS12175
uniprot id: F6CW64
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS10670
gene id: 491952:MAR181_RS10670
uniprot id: F6CTK9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

491952:MAR181 RS00360
gene id: 491952:MAR181_RS00360
uniprot id: F6CZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

491952:MAR181 RS04555
gene id: 491952:MAR181_RS04555
uniprot id: F6CSV2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

491952:MAR181 RS16205
gene id: 491952:MAR181_RS16205
uniprot id: F6CSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS02865
gene id: 491952:MAR181_RS02865
uniprot id: F6D0B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

491952:MAR181 RS10270
gene id: 491952:MAR181_RS10270
uniprot id: F6CSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS04085
gene id: 491952:MAR181_RS04085
uniprot id: F6CS65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

491952:MAR181 RS09485
gene id: 491952:MAR181_RS09485
uniprot id: F6D188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

491952:MAR181 RS17760
gene id: 491952:MAR181_RS17760
uniprot id: F6CVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS01480
gene id: 491952:MAR181_RS01480
uniprot id: F6CXQ2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03155
gene id: 491952:MAR181_RS03155
uniprot id: F6D0G2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

491952:MAR181 RS09100
gene id: 491952:MAR181_RS09100
uniprot id: F6D0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

491952:MAR181 RS04905
gene id: 491952:MAR181_RS04905
uniprot id: F6CTG1
names: Similarity
messages: Belongs to the universal stress protein A family.

491952:MAR181 RS08145
gene id: 491952:MAR181_RS08145
uniprot id: F6CZA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

491952:MAR181 RS02870
gene id: 491952:MAR181_RS02870
uniprot id: F6D0B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

491952:MAR181 RS13725
gene id: 491952:MAR181_RS13725
uniprot id: F6CYP3
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

491952:MAR181 RS13085
gene id: 491952:MAR181_RS13085
uniprot id: F6CXI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS10090
gene id: 491952:MAR181_RS10090
uniprot id: F6CSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

491952:MAR181 RS07770
gene id: 491952:MAR181_RS07770
uniprot id: F6CYF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

491952:MAR181 RS15640
gene id: 491952:MAR181_RS15640
uniprot id: F6CRZ6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

491952:MAR181 RS14105
gene id: 491952:MAR181_RS14105
uniprot id: F6CZJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

491952:MAR181 RS10520
gene id: 491952:MAR181_RS10520
uniprot id: F6CT36
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS02440
gene id: 491952:MAR181_RS02440
uniprot id: F6CZP4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

491952:MAR181 RS06270
gene id: 491952:MAR181_RS06270
uniprot id: F6CVY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS17025
gene id: 491952:MAR181_RS17025
uniprot id: F6CUF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

491952:MAR181 RS09465
gene id: 491952:MAR181_RS09465
uniprot id: F6D184
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

491952:MAR181 RS03675
gene id: 491952:MAR181_RS03675
uniprot id: F6CRL3
names: Similarity
messages: Belongs to the thioredoxin family.

491952:MAR181 RS10010
gene id: 491952:MAR181_RS10010
uniprot id: F6CSE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

491952:MAR181 RS07405
gene id: 491952:MAR181_RS07405
uniprot id: F6CXU7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS07990
gene id: 491952:MAR181_RS07990
uniprot id: F6CYK3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

491952:MAR181 RS15415
gene id: 491952:MAR181_RS15415
uniprot id: F6D1G9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

491952:MAR181 RS03150
gene id: 491952:MAR181_RS03150
uniprot id: F6D0G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS10725
gene id: 491952:MAR181_RS10725
uniprot id: F6CTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

491952:MAR181 RS15105
gene id: 491952:MAR181_RS15105
uniprot id: F6D0W5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

491952:MAR181 RS14870
gene id: 491952:MAR181_RS14870
uniprot id: F6D0R8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

491952:MAR181 RS01975
gene id: 491952:MAR181_RS01975
uniprot id: F6CYD6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS02065
gene id: 491952:MAR181_RS02065
uniprot id: F6CZ24
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS15790
gene id: 491952:MAR181_RS15790
uniprot id: F6CS27
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

491952:MAR181 RS09365
gene id: 491952:MAR181_RS09365
uniprot id: F6D164
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

491952:MAR181 RS08150
gene id: 491952:MAR181_RS08150
uniprot id: F6CZA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

491952:MAR181 RS14045
gene id: 491952:MAR181_RS14045
uniprot id: F6CZH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS07260
gene id: 491952:MAR181_RS07260
uniprot id: F6CXC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

491952:MAR181 RS15200
gene id: 491952:MAR181_RS15200
uniprot id: F6D1C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

491952:MAR181 RS17220
gene id: 491952:MAR181_RS17220
uniprot id: F6CUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS14245
gene id: 491952:MAR181_RS14245
uniprot id: F6CZL7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

491952:MAR181 RS16870
gene id: 491952:MAR181_RS16870
uniprot id: F6CTX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS02655
gene id: 491952:MAR181_RS02655
uniprot id: F6CZT7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

491952:MAR181 RS01215
gene id: 491952:MAR181_RS01215
uniprot id: F6CX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS10420
gene id: 491952:MAR181_RS10420
uniprot id: F6CT17
names: Similarity
messages: Belongs to the universal stress protein A family.

491952:MAR181 RS12820
gene id: 491952:MAR181_RS12820
uniprot id: F6CWZ1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS17300
gene id: 491952:MAR181_RS17300
uniprot id: F6CUK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS13370
gene id: 491952:MAR181_RS13370
uniprot id: F6CY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

491952:MAR181 RS04860
gene id: 491952:MAR181_RS04860
uniprot id: F6CTF2
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS10140
gene id: 491952:MAR181_RS10140
uniprot id: F6CSH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

491952:MAR181 RS17655
gene id: 491952:MAR181_RS17655
uniprot id: F6CV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS15605
gene id: 491952:MAR181_RS15605
uniprot id: F6CRY9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

491952:MAR181 RS17860
gene id: 491952:MAR181_RS17860
uniprot id: F6CVQ8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

491952:MAR181 RS01500
gene id: 491952:MAR181_RS01500
uniprot id: F6CXQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

491952:MAR181 RS09360
gene id: 491952:MAR181_RS09360
uniprot id: F6D163
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

491952:MAR181 RS17940
gene id: 491952:MAR181_RS17940
uniprot id: F6CVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

491952:MAR181 RS14445
gene id: 491952:MAR181_RS14445
uniprot id: F6D044
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

491952:MAR181 RS04375
gene id: 491952:MAR181_RS04375
uniprot id: F6CSR9
names: Similarity
messages: Belongs to the YciI family.

491952:MAR181 RS04035
gene id: 491952:MAR181_RS04035
uniprot id: F6CS55
names: Similarity
messages: Belongs to the MipA/OmpV family.

491952:MAR181 RS06520
gene id: 491952:MAR181_RS06520
uniprot id: F6CW36
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

491952:MAR181 RS00095
gene id: 491952:MAR181_RS00095
uniprot id: F6CYW0
names: Similarity
messages: Belongs to the HSP15 family.

491952:MAR181 RS08345
gene id: 491952:MAR181_RS08345
uniprot id: F6CZE6
names: Similarity
messages: Belongs to the ArsC family.

491952:MAR181 RS07225
gene id: 491952:MAR181_RS07225
uniprot id: F6CXC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

491952:MAR181 RS14240
gene id: 491952:MAR181_RS14240
uniprot id: F6CZL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

491952:MAR181 RS14250
gene id: 491952:MAR181_RS14250
uniprot id: F6CZL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

491952:MAR181 RS16775
gene id: 491952:MAR181_RS16775
uniprot id: F6CTV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS14850
gene id: 491952:MAR181_RS14850
uniprot id: F6D0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

491952:MAR181 RS11715
gene id: 491952:MAR181_RS11715
uniprot id: F6CV07
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

491952:MAR181 RS08410
gene id: 491952:MAR181_RS08410
uniprot id: F6CZF6
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS14755
gene id: 491952:MAR181_RS14755
uniprot id: F6D0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS13235
gene id: 491952:MAR181_RS13235
uniprot id: F6CXZ5
names: Similarity
messages: Belongs to the Smp family.

491952:MAR181 RS04175
gene id: 491952:MAR181_RS04175
uniprot id: F6CS82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

491952:MAR181 RS17885
gene id: 491952:MAR181_RS17885
uniprot id: F6CVR3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

491952:MAR181 RS02630
gene id: 491952:MAR181_RS02630
uniprot id: F6CZT2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

491952:MAR181 RS15985
gene id: 491952:MAR181_RS15985
uniprot id: F6CSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

491952:MAR181 RS07120
gene id: 491952:MAR181_RS07120
uniprot id: F6CXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

491952:MAR181 RS01820
gene id: 491952:MAR181_RS01820
uniprot id: F6CYA5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

491952:MAR181 RS09475
gene id: 491952:MAR181_RS09475
uniprot id: F6D186
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

491952:MAR181 RS13680
gene id: 491952:MAR181_RS13680
uniprot id: F6CYN4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

491952:MAR181 RS00660
gene id: 491952:MAR181_RS00660
uniprot id: F6CWE5
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

491952:MAR181 RS04485
gene id: 491952:MAR181_RS04485
uniprot id: F6CSU1
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

491952:MAR181 RS15140
gene id: 491952:MAR181_RS15140
uniprot id: F6D1B5
names: Similarity
messages: Belongs to the leucine-binding protein family.

491952:MAR181 RS03790
gene id: 491952:MAR181_RS03790
uniprot id: F6CRN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS08505
gene id: 491952:MAR181_RS08505
uniprot id: F6CZX2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

491952:MAR181 RS10805
gene id: 491952:MAR181_RS10805
uniprot id: F6CTN5
names: Similarity
messages: Belongs to the DEAD box helicase family.

491952:MAR181 RS17055
gene id: 491952:MAR181_RS17055
uniprot id: F6CUF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

491952:MAR181 RS09330
gene id: 491952:MAR181_RS09330
uniprot id: F6D157
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS10260
gene id: 491952:MAR181_RS10260
uniprot id: F6CSZ1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

491952:MAR181 RS01180
gene id: 491952:MAR181_RS01180
uniprot id: F6CX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS03060
gene id: 491952:MAR181_RS03060
uniprot id: F6D0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

491952:MAR181 RS15015
gene id: 491952:MAR181_RS15015
uniprot id: F6D0U7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS05435
gene id: 491952:MAR181_RS05435
uniprot id: F6CU66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

491952:MAR181 RS08455
gene id: 491952:MAR181_RS08455
uniprot id: F6CZW2
names: Similarity
messages: Belongs to the GSP E family.

491952:MAR181 RS07270
gene id: 491952:MAR181_RS07270
uniprot id: F6CXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

491952:MAR181 RS11400
gene id: 491952:MAR181_RS11400
uniprot id: F6CUU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

491952:MAR181 RS02095
gene id: 491952:MAR181_RS02095
uniprot id: F6CZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

491952:MAR181 RS03190
gene id: 491952:MAR181_RS03190
uniprot id: F6D0W8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

491952:MAR181 RS07070
gene id: 491952:MAR181_RS07070
uniprot id: F6CX91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS18385
gene id: 491952:MAR181_RS18385
uniprot id: F6CY23
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS11620
gene id: 491952:MAR181_RS11620
uniprot id: F6CUY7
names: Similarity
messages: Belongs to the Gfa family.

491952:MAR181 RS07750
gene id: 491952:MAR181_RS07750
uniprot id: F6CYF3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

491952:MAR181 RS04970
gene id: 491952:MAR181_RS04970
uniprot id: F6CTH4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

491952:MAR181 RS15760
gene id: 491952:MAR181_RS15760
uniprot id: F6CS21
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

491952:MAR181 RS04205
gene id: 491952:MAR181_RS04205
uniprot id: F6CS88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

491952:MAR181 RS02255
gene id: 491952:MAR181_RS02255
uniprot id: F6CZ62
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

491952:MAR181 RS13865
gene id: 491952:MAR181_RS13865
uniprot id: F6CYS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

491952:MAR181 RS01170
gene id: 491952:MAR181_RS01170
uniprot id: F6CX48
names: Similarity
messages: Belongs to the peptidase S58 family.

491952:MAR181 RS13845
gene id: 491952:MAR181_RS13845
uniprot id: F6CYR7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

491952:MAR181 RS02550
gene id: 491952:MAR181_RS02550
uniprot id: F6CZR6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

491952:MAR181 RS10560
gene id: 491952:MAR181_RS10560
uniprot id: F6CT45
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

491952:MAR181 RS13005
gene id: 491952:MAR181_RS13005
uniprot id: F6CXH2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

491952:MAR181 RS01620
gene id: 491952:MAR181_RS01620
uniprot id: F6CXS7
names: Similarity
messages: Belongs to the histone deacetylase family.

491952:MAR181 RS12785
gene id: 491952:MAR181_RS12785
uniprot id: F6CWY4
names: Similarity
messages: Belongs to the glutamine synthetase family.

491952:MAR181 RS17130
gene id: 491952:MAR181_RS17130
uniprot id: F6CUG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03395
gene id: 491952:MAR181_RS03395
uniprot id: F6D109
names: Similarity
messages: Belongs to the aspartokinase family.

491952:MAR181 RS13340
gene id: 491952:MAR181_RS13340
uniprot id: F6CY16
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

491952:MAR181 RS13785
gene id: 491952:MAR181_RS13785
uniprot id: F6CYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

491952:MAR181 RS03430
gene id: 491952:MAR181_RS03430
uniprot id: F6D112
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

491952:MAR181 RS14350
gene id: 491952:MAR181_RS14350
uniprot id: F6D025
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

491952:MAR181 RS00270
gene id: 491952:MAR181_RS00270
uniprot id: F6CYZ5
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS06535
gene id: 491952:MAR181_RS06535
uniprot id: F6CW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

491952:MAR181 RS17330
gene id: 491952:MAR181_RS17330
uniprot id: F6CUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

491952:MAR181 RS02605
gene id: 491952:MAR181_RS02605
uniprot id: F6CZS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS04245
gene id: 491952:MAR181_RS04245
uniprot id: F6CS96
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

491952:MAR181 RS05010
gene id: 491952:MAR181_RS05010
uniprot id: F6CTI2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03185
gene id: 491952:MAR181_RS03185
uniprot id: F6D0W7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

491952:MAR181 RS07150
gene id: 491952:MAR181_RS07150
uniprot id: F6CXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS00970
gene id: 491952:MAR181_RS00970
uniprot id: F6CX09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

491952:MAR181 RS07140
gene id: 491952:MAR181_RS07140
uniprot id: F6CXA5
names: Similarity
messages: Belongs to the asparaginase 1 family.

491952:MAR181 RS07360
gene id: 491952:MAR181_RS07360
uniprot id: F6CXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

491952:MAR181 RS10545
gene id: 491952:MAR181_RS10545
uniprot id: F6CT42
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

491952:MAR181 RS02120
gene id: 491952:MAR181_RS02120
uniprot id: F6CZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

491952:MAR181 RS15745
gene id: 491952:MAR181_RS15745
uniprot id: F6CS18
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS05305
gene id: 491952:MAR181_RS05305
uniprot id: F6CU38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

491952:MAR181 RS14715
gene id: 491952:MAR181_RS14715
uniprot id: F6D095
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

491952:MAR181 RS17910
gene id: 491952:MAR181_RS17910
uniprot id: F6CVR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

491952:MAR181 RS17870
gene id: 491952:MAR181_RS17870
uniprot id: F6CVR0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

491952:MAR181 RS17965
gene id: 491952:MAR181_RS17965
uniprot id: F6CVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

491952:MAR181 RS17880
gene id: 491952:MAR181_RS17880
uniprot id: F6CVR2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS15030
gene id: 491952:MAR181_RS15030
uniprot id: F6D0V0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

491952:MAR181 RS00365
gene id: 491952:MAR181_RS00365
uniprot id: F6CZ14
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

491952:MAR181 RS10045
gene id: 491952:MAR181_RS10045
uniprot id: F6CSF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

491952:MAR181 RS14295
gene id: 491952:MAR181_RS14295
uniprot id: F6CZM6
names: Similarity
messages: Belongs to the TrpC family.

491952:MAR181 RS13210
gene id: 491952:MAR181_RS13210
uniprot id: F6CXK6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

491952:MAR181 RS02455
gene id: 491952:MAR181_RS02455
uniprot id: F6CZP7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

491952:MAR181 RS06045
gene id: 491952:MAR181_RS06045
uniprot id: F6CVD1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

491952:MAR181 RS16920
gene id: 491952:MAR181_RS16920
uniprot id: F6CTY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

491952:MAR181 RS17700
gene id: 491952:MAR181_RS17700
uniprot id: F6CV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

491952:MAR181 RS13555
gene id: 491952:MAR181_RS13555
uniprot id: F6CY59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

491952:MAR181 RS13535
gene id: 491952:MAR181_RS13535
uniprot id: F6CY55
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

491952:MAR181 RS11080
gene id: 491952:MAR181_RS11080
uniprot id: F6CU86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS18115
gene id: 491952:MAR181_RS18115
uniprot id: F6CUX6
names: Similarity
messages: Belongs to the AHA1 family.

491952:MAR181 RS08270
gene id: 491952:MAR181_RS08270
uniprot id: F6CZD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

491952:MAR181 RS06765
gene id: 491952:MAR181_RS06765
uniprot id: F6CWN3
names: Similarity
messages: Belongs to the MYG1 family.

491952:MAR181 RS13700
gene id: 491952:MAR181_RS13700
uniprot id: F6CYN8
names: Similarity
messages: Belongs to the class-I fumarase family.

491952:MAR181 RS07215
gene id: 491952:MAR181_RS07215
uniprot id: F6CXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

491952:MAR181 RS13870
gene id: 491952:MAR181_RS13870
uniprot id: F6CYS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

491952:MAR181 RS09745
gene id: 491952:MAR181_RS09745
uniprot id: F6CRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

491952:MAR181 RS13495
gene id: 491952:MAR181_RS13495
uniprot id: F6CY47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

491952:MAR181 RS15970
gene id: 491952:MAR181_RS15970
uniprot id: F6CSL1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

491952:MAR181 RS14640
gene id: 491952:MAR181_RS14640
uniprot id: F6D080
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS01435
gene id: 491952:MAR181_RS01435
uniprot id: F6CXP2
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS10795
gene id: 491952:MAR181_RS10795
uniprot id: F6CTN3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

491952:MAR181 RS04840
gene id: 491952:MAR181_RS04840
uniprot id: F6CTE8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

491952:MAR181 RS10300
gene id: 491952:MAR181_RS10300
uniprot id: F6CSZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

491952:MAR181 RS04560
gene id: 491952:MAR181_RS04560
uniprot id: F6CSV3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

491952:MAR181 RS12135
gene id: 491952:MAR181_RS12135
uniprot id: F6CW56
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

491952:MAR181 RS09770
gene id: 491952:MAR181_RS09770
uniprot id: F6CRU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS10430
gene id: 491952:MAR181_RS10430
uniprot id: F6CT19
names: Similarity
messages: Belongs to the band 7/mec-2 family.

491952:MAR181 RS00110
gene id: 491952:MAR181_RS00110
uniprot id: F6CYW3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

491952:MAR181 RS17820
gene id: 491952:MAR181_RS17820
uniprot id: F6CVQ0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

491952:MAR181 RS17810
gene id: 491952:MAR181_RS17810
uniprot id: F6CVP8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS14585
gene id: 491952:MAR181_RS14585
uniprot id: F6D071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS09335
gene id: 491952:MAR181_RS09335
uniprot id: F6D158
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

491952:MAR181 RS11335
gene id: 491952:MAR181_RS11335
uniprot id: F6CUD6
names: Similarity
messages: Belongs to the CFA/CMAS family.

491952:MAR181 RS10100
gene id: 491952:MAR181_RS10100
uniprot id: F6CSG3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

491952:MAR181 RS09005
gene id: 491952:MAR181_RS09005
uniprot id: F6D0K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

491952:MAR181 RS03400
gene id: 491952:MAR181_RS03400
uniprot id: F6D110
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

491952:MAR181 RS04255
gene id: 491952:MAR181_RS04255
uniprot id: F6CS98
names: Similarity
messages: Belongs to the MotB family.

491952:MAR181 RS09380
gene id: 491952:MAR181_RS09380
uniprot id: F6D167
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

491952:MAR181 RS15510
gene id: 491952:MAR181_RS15510
uniprot id: F6CRX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

491952:MAR181 RS08095
gene id: 491952:MAR181_RS08095
uniprot id: F6CZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

491952:MAR181 RS14345
gene id: 491952:MAR181_RS14345
uniprot id: F6CZN6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

491952:MAR181 RS00455
gene id: 491952:MAR181_RS00455
uniprot id: F6CVV1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS16935
gene id: 491952:MAR181_RS16935
uniprot id: F6CTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

491952:MAR181 RS01980
gene id: 491952:MAR181_RS01980
uniprot id: F6CYD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS02510
gene id: 491952:MAR181_RS02510
uniprot id: F6CZQ9
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS01015
gene id: 491952:MAR181_RS01015
uniprot id: F6CX18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

491952:MAR181 RS01495
gene id: 491952:MAR181_RS01495
uniprot id: F6CXQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

491952:MAR181 RS01935
gene id: 491952:MAR181_RS01935
uniprot id: F6CYC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

491952:MAR181 RS01420
gene id: 491952:MAR181_RS01420
uniprot id: F6CXN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS16970
gene id: 491952:MAR181_RS16970
uniprot id: F6CTZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

491952:MAR181 RS14205
gene id: 491952:MAR181_RS14205
uniprot id: F6CZK9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

491952:MAR181 RS07195
gene id: 491952:MAR181_RS07195
uniprot id: F6CXB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

491952:MAR181 RS10250
gene id: 491952:MAR181_RS10250
uniprot id: F6CSY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS14775
gene id: 491952:MAR181_RS14775
uniprot id: F6D0P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS07465
gene id: 491952:MAR181_RS07465
uniprot id: F6CXV9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

491952:MAR181 RS17890
gene id: 491952:MAR181_RS17890
uniprot id: F6CVR4
names: Similarity
messages: Belongs to the SufE family.

491952:MAR181 RS12415
gene id: 491952:MAR181_RS12415
uniprot id: F6CWB1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

491952:MAR181 RS04935
gene id: 491952:MAR181_RS04935
uniprot id: F6CTG7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

491952:MAR181 RS14960
gene id: 491952:MAR181_RS14960
uniprot id: F6D0T6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

491952:MAR181 RS12705
gene id: 491952:MAR181_RS12705
uniprot id: F6CWW8
names: Similarity
messages: Belongs to the VgrG protein family.

491952:MAR181 RS08440
gene id: 491952:MAR181_RS08440
uniprot id: F6CZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

491952:MAR181 RS18095
gene id: 491952:MAR181_RS18095
uniprot id: F6CUA4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

491952:MAR181 RS14185
gene id: 491952:MAR181_RS14185
uniprot id: F6CZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

491952:MAR181 RS06980
gene id: 491952:MAR181_RS06980
uniprot id: F6CX73
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS06560
gene id: 491952:MAR181_RS06560
uniprot id: F6CW44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS15130
gene id: 491952:MAR181_RS15130
uniprot id: F6D1B3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS09135
gene id: 491952:MAR181_RS09135
uniprot id: F6D0M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

491952:MAR181 RS11040
gene id: 491952:MAR181_RS11040
uniprot id: F6CU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

491952:MAR181 RS04875
gene id: 491952:MAR181_RS04875
uniprot id: F6CTF5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

491952:MAR181 RS09800
gene id: 491952:MAR181_RS09800
uniprot id: F6CRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS09110
gene id: 491952:MAR181_RS09110
uniprot id: F6D0M1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

491952:MAR181 RS01580
gene id: 491952:MAR181_RS01580
uniprot id: F6CXS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

491952:MAR181 RS08445
gene id: 491952:MAR181_RS08445
uniprot id: F6CZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

491952:MAR181 RS03090
gene id: 491952:MAR181_RS03090
uniprot id: F6D0E9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

491952:MAR181 RS11775
gene id: 491952:MAR181_RS11775
uniprot id: F6CVG8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS14030
gene id: 491952:MAR181_RS14030
uniprot id: F6CZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

491952:MAR181 RS07460
gene id: 491952:MAR181_RS07460
uniprot id: F6CXV8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

491952:MAR181 RS16760
gene id: 491952:MAR181_RS16760
uniprot id: F6CTV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

491952:MAR181 RS17795
gene id: 491952:MAR181_RS17795
uniprot id: F6CVP5
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

491952:MAR181 RS15420
gene id: 491952:MAR181_RS15420
uniprot id: F6D1H0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

491952:MAR181 RS14410
gene id: 491952:MAR181_RS14410
uniprot id: F6D037
names: Similarity
messages: Belongs to the PhoH family.

491952:MAR181 RS10865
gene id: 491952:MAR181_RS10865
uniprot id: F6CTP6
names: Similarity
messages: Belongs to the UPF0231 family.

491952:MAR181 RS11390
gene id: 491952:MAR181_RS11390
uniprot id: F6CUU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS12800
gene id: 491952:MAR181_RS12800
uniprot id: F6CWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS09615
gene id: 491952:MAR181_RS09615
uniprot id: F6CRR8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

491952:MAR181 RS01540
gene id: 491952:MAR181_RS01540
uniprot id: F6CXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

491952:MAR181 RS10890
gene id: 491952:MAR181_RS10890
uniprot id: F6CTQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS00040
gene id: 491952:MAR181_RS00040
uniprot id: F6CYU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS00240
gene id: 491952:MAR181_RS00240
uniprot id: F6CYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

491952:MAR181 RS13405
gene id: 491952:MAR181_RS13405
uniprot id: F6CY29
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

491952:MAR181 RS08045
gene id: 491952:MAR181_RS08045
uniprot id: F6CYL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

491952:MAR181 RS05760
gene id: 491952:MAR181_RS05760
uniprot id: F6CUS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

491952:MAR181 RS09180
gene id: 491952:MAR181_RS09180
uniprot id: F6D0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS12300
gene id: 491952:MAR181_RS12300
uniprot id: F6CW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

491952:MAR181 RS14455
gene id: 491952:MAR181_RS14455
uniprot id: F6D046
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

491952:MAR181 RS05495
gene id: 491952:MAR181_RS05495
uniprot id: F6CUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS09215
gene id: 491952:MAR181_RS09215
uniprot id: F6D132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS01295
gene id: 491952:MAR181_RS01295
uniprot id: F6CXL4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS09575
gene id: 491952:MAR181_RS09575
uniprot id: F6D1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

491952:MAR181 RS13180
gene id: 491952:MAR181_RS13180
uniprot id: F6CXK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

491952:MAR181 RS09345
gene id: 491952:MAR181_RS09345
uniprot id: F6D160
names: Similarity
messages: Belongs to the phosphohexose mutase family.

491952:MAR181 RS08105
gene id: 491952:MAR181_RS08105
uniprot id: F6CZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

491952:MAR181 RS04060
gene id: 491952:MAR181_RS04060
uniprot id: F6CS60
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

491952:MAR181 RS12640
gene id: 491952:MAR181_RS12640
uniprot id: F6CWV5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

491952:MAR181 RS15260
gene id: 491952:MAR181_RS15260
uniprot id: F6D1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS07810
gene id: 491952:MAR181_RS07810
uniprot id: F6CYG5
names: Similarity
messages: Belongs to the MlaA family.

491952:MAR181 RS07200
gene id: 491952:MAR181_RS07200
uniprot id: F6CXB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

491952:MAR181 RS08060
gene id: 491952:MAR181_RS08060
uniprot id: F6CYL7
names: Similarity
messages: Belongs to the DEAD box helicase family.

491952:MAR181 RS07310
gene id: 491952:MAR181_RS07310
uniprot id: F6CXD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

491952:MAR181 RS04305
gene id: 491952:MAR181_RS04305
uniprot id: F6CSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

491952:MAR181 RS17225
gene id: 491952:MAR181_RS17225
uniprot id: F6CUI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS15845
gene id: 491952:MAR181_RS15845
uniprot id: F6CS38
names: Similarity
messages: Belongs to the OsmC/Ohr family.

491952:MAR181 RS04280
gene id: 491952:MAR181_RS04280
uniprot id: F6CSA3
names: Similarity
messages: Belongs to the type III secretion exporter family.

491952:MAR181 RS07985
gene id: 491952:MAR181_RS07985
uniprot id: F6CYK2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

491952:MAR181 RS16305
gene id: 491952:MAR181_RS16305
uniprot id: F6CT71
names: Similarity
messages: Belongs to the glutamate synthase family.

491952:MAR181 RS05820
gene id: 491952:MAR181_RS05820
uniprot id: F6CV88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

491952:MAR181 RS16455
gene id: 491952:MAR181_RS16455
uniprot id: F6CTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS13950
gene id: 491952:MAR181_RS13950
uniprot id: F6CYT9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

491952:MAR181 RS02760
gene id: 491952:MAR181_RS02760
uniprot id: F6CZV5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

491952:MAR181 RS00830
gene id: 491952:MAR181_RS00830
uniprot id: F6CWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS04045
gene id: 491952:MAR181_RS04045
uniprot id: F6CS57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

491952:MAR181 RS13155
gene id: 491952:MAR181_RS13155
uniprot id: F6CXJ5
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS03375
gene id: 491952:MAR181_RS03375
uniprot id: F6D105
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

491952:MAR181 RS03040
gene id: 491952:MAR181_RS03040
uniprot id: F6D0D9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

491952:MAR181 RS17635
gene id: 491952:MAR181_RS17635
uniprot id: F6CV67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS04220
gene id: 491952:MAR181_RS04220
uniprot id: F6CS91
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

491952:MAR181 RS08400
gene id: 491952:MAR181_RS08400
uniprot id: F6CZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS00435
gene id: 491952:MAR181_RS00435
uniprot id: F6CVU7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

491952:MAR181 RS11365
gene id: 491952:MAR181_RS11365
uniprot id: F6CUT6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the N-terminal section; belongs to the CdiA toxin family.
messages: target cell cytoplasm

491952:MAR181 RS11025
gene id: 491952:MAR181_RS11025
uniprot id: F6CU75
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS15445
gene id: 491952:MAR181_RS15445
uniprot id: F6D1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

491952:MAR181 RS01185
gene id: 491952:MAR181_RS01185
uniprot id: F6CX51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

491952:MAR181 RS10255
gene id: 491952:MAR181_RS10255
uniprot id: F6CSZ0
names: Similarity
messages: Belongs to the PrpF family.

491952:MAR181 RS10370
gene id: 491952:MAR181_RS10370
uniprot id: F6CT13
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS06555
gene id: 491952:MAR181_RS06555
uniprot id: F6CW43
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

491952:MAR181 RS17660
gene id: 491952:MAR181_RS17660
uniprot id: F6CV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS09375
gene id: 491952:MAR181_RS09375
uniprot id: F6D166
names: Similarity
messages: Belongs to the UPF0434 family.

491952:MAR181 RS07780
gene id: 491952:MAR181_RS07780
uniprot id: F6CYF9
names: Similarity
messages: Belongs to the UPF0260 family.

491952:MAR181 RS16145
gene id: 491952:MAR181_RS16145
uniprot id: F6CSP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS15465
gene id: 491952:MAR181_RS15465
uniprot id: F6D1H9
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

491952:MAR181 RS10210
gene id: 491952:MAR181_RS10210
uniprot id: F6CSI5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS10680
gene id: 491952:MAR181_RS10680
uniprot id: F6CTL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

491952:MAR181 RS05350
gene id: 491952:MAR181_RS05350
uniprot id: F6CU48
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

491952:MAR181 RS17775
gene id: 491952:MAR181_RS17775
uniprot id: F6CVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS05330
gene id: 491952:MAR181_RS05330
uniprot id: F6CU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS02950
gene id: 491952:MAR181_RS02950
uniprot id: F6D0C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

491952:MAR181 RS03075
gene id: 491952:MAR181_RS03075
uniprot id: F6D0E6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS14270
gene id: 491952:MAR181_RS14270
uniprot id: F6CZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

491952:MAR181 RS04790
gene id: 491952:MAR181_RS04790
uniprot id: F6CTD8
names: Similarity
messages: Belongs to the glutamate synthase family.

491952:MAR181 RS06300
gene id: 491952:MAR181_RS06300
uniprot id: F6CVZ2
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS13690
gene id: 491952:MAR181_RS13690
uniprot id: F6CYN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS09165
gene id: 491952:MAR181_RS09165
uniprot id: F6D0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

491952:MAR181 RS16340
gene id: 491952:MAR181_RS16340
uniprot id: F6CT78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

491952:MAR181 RS06585
gene id: 491952:MAR181_RS06585
uniprot id: F6CWJ8
names: Similarity
messages: Belongs to the GcvT family.

491952:MAR181 RS11815
gene id: 491952:MAR181_RS11815
uniprot id: F6CVH6
names: Similarity
messages: Belongs to the HisA/HisF family.

491952:MAR181 RS06410
gene id: 491952:MAR181_RS06410
uniprot id: F6CW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS00820
gene id: 491952:MAR181_RS00820
uniprot id: F6CWH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS17590
gene id: 491952:MAR181_RS17590
uniprot id: F6CV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS15160
gene id: 491952:MAR181_RS15160
uniprot id: F6D1B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

491952:MAR181 RS15070
gene id: 491952:MAR181_RS15070
uniprot id: F6D0V8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS12475
gene id: 491952:MAR181_RS12475
uniprot id: F6CWS2
names: Similarity
messages: Belongs to the SufE family.

491952:MAR181 RS04195
gene id: 491952:MAR181_RS04195
uniprot id: F6CS86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

491952:MAR181 RS17710
gene id: 491952:MAR181_RS17710
uniprot id: F6CV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS17990
gene id: 491952:MAR181_RS17990
uniprot id: F6CVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

491952:MAR181 RS17085
gene id: 491952:MAR181_RS17085
uniprot id: F6CUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

491952:MAR181 RS04870
gene id: 491952:MAR181_RS04870
uniprot id: F6CTF4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS04250
gene id: 491952:MAR181_RS04250
uniprot id: F6CS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

491952:MAR181 RS08955
gene id: 491952:MAR181_RS08955
uniprot id: F6D0J2
names: Similarity
messages: Belongs to the SUI1 family.

491952:MAR181 RS13335
gene id: 491952:MAR181_RS13335
uniprot id: F6CY15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

491952:MAR181 RS12125
gene id: 491952:MAR181_RS12125
uniprot id: F6CW54
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

491952:MAR181 RS17750
gene id: 491952:MAR181_RS17750
uniprot id: F6CVN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

491952:MAR181 RS06150
gene id: 491952:MAR181_RS06150
uniprot id: F6CVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

491952:MAR181 RS16785
gene id: 491952:MAR181_RS16785
uniprot id: F6CTV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

491952:MAR181 RS08745
gene id: 491952:MAR181_RS08745
uniprot id: F6D008
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

491952:MAR181 RS11325
gene id: 491952:MAR181_RS11325
uniprot id: F6CUD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS00740
gene id: 491952:MAR181_RS00740
uniprot id: F6CWG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS09140
gene id: 491952:MAR181_RS09140
uniprot id: F6D0M7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

491952:MAR181 RS08075
gene id: 491952:MAR181_RS08075
uniprot id: F6CZ92
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

491952:MAR181 RS05590
gene id: 491952:MAR181_RS05590
uniprot id: F6CUP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS14275
gene id: 491952:MAR181_RS14275
uniprot id: F6CZM3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

491952:MAR181 RS08740
gene id: 491952:MAR181_RS08740
uniprot id: F6D007
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

491952:MAR181 RS09160
gene id: 491952:MAR181_RS09160
uniprot id: F6D0N1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

491952:MAR181 RS06365
gene id: 491952:MAR181_RS06365
uniprot id: F6CW05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

491952:MAR181 RS02115
gene id: 491952:MAR181_RS02115
uniprot id: F6CZ34
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

491952:MAR181 RS01635
gene id: 491952:MAR181_RS01635
uniprot id: F6CXT0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

491952:MAR181 RS03820
gene id: 491952:MAR181_RS03820
uniprot id: F6CRN7
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

491952:MAR181 RS06655
gene id: 491952:MAR181_RS06655
uniprot id: F6CWL2
names: Subcellular Location Annotation
messages: Secreted

491952:MAR181 RS13730
gene id: 491952:MAR181_RS13730
uniprot id: F6CYP4
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

491952:MAR181 RS09665
gene id: 491952:MAR181_RS09665
uniprot id: F6CRS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

491952:MAR181 RS07350
gene id: 491952:MAR181_RS07350
uniprot id: F6CXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

491952:MAR181 RS07190
gene id: 491952:MAR181_RS07190
uniprot id: F6CXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

491952:MAR181 RS02590
gene id: 491952:MAR181_RS02590
uniprot id: F6CZS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS06165
gene id: 491952:MAR181_RS06165
uniprot id: F6CVF4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

491952:MAR181 RS05410
gene id: 491952:MAR181_RS05410
uniprot id: F6CU61
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

491952:MAR181 RS10595
gene id: 491952:MAR181_RS10595
uniprot id: F6CT52
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

491952:MAR181 RS17030
gene id: 491952:MAR181_RS17030
uniprot id: F6CUF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS15600
gene id: 491952:MAR181_RS15600
uniprot id: F6CRY7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

491952:MAR181 RS17335
gene id: 491952:MAR181_RS17335
uniprot id: F6CUK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

491952:MAR181 RS04605
gene id: 491952:MAR181_RS04605
uniprot id: F6CSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS12425
gene id: 491952:MAR181_RS12425
uniprot id: F6CWB3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

491952:MAR181 RS13810
gene id: 491952:MAR181_RS13810
uniprot id: F6CYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS01675
gene id: 491952:MAR181_RS01675
uniprot id: F6CY74
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS11125
gene id: 491952:MAR181_RS11125
uniprot id: F6CU95
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

491952:MAR181 RS17715
gene id: 491952:MAR181_RS17715
uniprot id: F6CV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS08800
gene id: 491952:MAR181_RS08800
uniprot id: F6D019
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS05205
gene id: 491952:MAR181_RS05205
uniprot id: F6CU18
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS16250
gene id: 491952:MAR181_RS16250
uniprot id: F6CT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS11420
gene id: 491952:MAR181_RS11420
uniprot id: F6CUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

491952:MAR181 RS00980
gene id: 491952:MAR181_RS00980
uniprot id: F6CX11
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

491952:MAR181 RS01665
gene id: 491952:MAR181_RS01665
uniprot id: F6CY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS17065
gene id: 491952:MAR181_RS17065
uniprot id: F6CUG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

491952:MAR181 RS08280
gene id: 491952:MAR181_RS08280
uniprot id: F6CZD3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

491952:MAR181 RS01005
gene id: 491952:MAR181_RS01005
uniprot id: F6CX16
names: Subcellular Location Annotation
messages: Cytoplasm

491952:MAR181 RS01355
gene id: 491952:MAR181_RS01355
uniprot id: F6CXM6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

491952:MAR181 RS13415
gene id: 491952:MAR181_RS13415
uniprot id: F6CY31
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

491952:MAR181 RS13285
gene id: 491952:MAR181_RS13285
uniprot id: F6CY05
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

491952:MAR181 RS06595
gene id: 491952:MAR181_RS06595
uniprot id: F6CWK0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

491952:MAR181 RS17165
gene id: 491952:MAR181_RS17165
uniprot id: F6CUH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS05255
gene id: 491952:MAR181_RS05255
uniprot id: F6CU28
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS11885
gene id: 491952:MAR181_RS11885
uniprot id: F6CVI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

491952:MAR181 RS04185
gene id: 491952:MAR181_RS04185
uniprot id: F6CS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

491952:MAR181 RS11260
gene id: 491952:MAR181_RS11260
uniprot id: F6CUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS14580
gene id: 491952:MAR181_RS14580
uniprot id: F6D070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS03510
gene id: 491952:MAR181_RS03510
uniprot id: F6D125
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

491952:MAR181 RS00795
gene id: 491952:MAR181_RS00795
uniprot id: F6CWH1
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

491952:MAR181 RS10360
gene id: 491952:MAR181_RS10360
uniprot id: F6CT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS07580
gene id: 491952:MAR181_RS07580
uniprot id: F6CXW6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS14470
gene id: 491952:MAR181_RS14470
uniprot id: F6D049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

491952:MAR181 RS06610
gene id: 491952:MAR181_RS06610
uniprot id: F6CWK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

491952:MAR181 RS14420
gene id: 491952:MAR181_RS14420
uniprot id: F6D039
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS00165
gene id: 491952:MAR181_RS00165
uniprot id: F6CYX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS13570
gene id: 491952:MAR181_RS13570
uniprot id: F6CY62
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

491952:MAR181 RS01060
gene id: 491952:MAR181_RS01060
uniprot id: F6CX27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS13955
gene id: 491952:MAR181_RS13955
uniprot id: F6CYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

491952:MAR181 RS02035
gene id: 491952:MAR181_RS02035
uniprot id: F6CZ19
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

491952:MAR181 RS06035
gene id: 491952:MAR181_RS06035
uniprot id: F6CVC9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS10155
gene id: 491952:MAR181_RS10155
uniprot id: F6CSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

491952:MAR181 RS12970
gene id: 491952:MAR181_RS12970
uniprot id: F6CXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

491952:MAR181 RS16940
gene id: 491952:MAR181_RS16940
uniprot id: F6CTY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS02570
gene id: 491952:MAR181_RS02570
uniprot id: F6CZS0
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

491952:MAR181 RS02150
gene id: 491952:MAR181_RS02150
uniprot id: F6CZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

491952:MAR181 RS16900
gene id: 491952:MAR181_RS16900
uniprot id: F6CTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

491952:MAR181 RS14855
gene id: 491952:MAR181_RS14855
uniprot id: F6D0R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

491952:MAR181 RS12035
gene id: 491952:MAR181_RS12035
uniprot id: F6CVM0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

491952:MAR181 RS02250
gene id: 491952:MAR181_RS02250
uniprot id: F6CZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

491952:MAR181 RS08140
gene id: 491952:MAR181_RS08140
uniprot id: F6CZA5
names: Similarity
messages: Belongs to the TrpF family.

491952:MAR181 RS07375
gene id: 491952:MAR181_RS07375
uniprot id: F6CXU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

491952:MAR181 RS00230
gene id: 491952:MAR181_RS00230
uniprot id: F6CYY7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

491952:MAR181 RS04210
gene id: 491952:MAR181_RS04210
uniprot id: F6CS89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

491952:MAR181 RS02130
gene id: 491952:MAR181_RS02130
uniprot id: F6CZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

491952:MAR181 RS14965
gene id: 491952:MAR181_RS14965
uniprot id: F6D0T7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS07760
gene id: 491952:MAR181_RS07760
uniprot id: F6CYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

491952:MAR181 RS13540
gene id: 491952:MAR181_RS13540
uniprot id: F6CY56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS07335
gene id: 491952:MAR181_RS07335
uniprot id: F6CXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

491952:MAR181 RS09010
gene id: 491952:MAR181_RS09010
uniprot id: F6D0K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

491952:MAR181 RS08190
gene id: 491952:MAR181_RS08190
uniprot id: F6CZB5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

491952:MAR181 RS07915
gene id: 491952:MAR181_RS07915
uniprot id: F6CYI8
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

491952:MAR181 RS09845
gene id: 491952:MAR181_RS09845
uniprot id: F6CRW4
names: Similarity
messages: Belongs to the glycosyl hydrolase.

491952:MAR181 RS16955
gene id: 491952:MAR181_RS16955
uniprot id: F6CTY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

491952:MAR181 RS07185
gene id: 491952:MAR181_RS07185
uniprot id: F6CXB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

491952:MAR181 RS09525
gene id: 491952:MAR181_RS09525
uniprot id: F6D196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

491952:MAR181 RS11845
gene id: 491952:MAR181_RS11845
uniprot id: F6CVI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

491952:MAR181 RS15150
gene id: 491952:MAR181_RS15150
uniprot id: F6D1B7
names: Similarity
messages: Belongs to the peptidase S41A family.

491952:MAR181 RS09605
gene id: 491952:MAR181_RS09605
uniprot id: F6CRR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

491952:MAR181 RS13065
gene id: 491952:MAR181_RS13065
uniprot id: F6CXI1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

491952:MAR181 RS12410
gene id: 491952:MAR181_RS12410
uniprot id: F6CWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

491952:MAR181 RS11985
gene id: 491952:MAR181_RS11985
uniprot id: F6CVK9
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS02540
gene id: 491952:MAR181_RS02540
uniprot id: F6CZR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

491952:MAR181 RS09045
gene id: 491952:MAR181_RS09045
uniprot id: F6D0K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

491952:MAR181 RS11760
gene id: 491952:MAR181_RS11760
uniprot id: F6CVG5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS06130
gene id: 491952:MAR181_RS06130
uniprot id: F6CVE7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

491952:MAR181 RS06440
gene id: 491952:MAR181_RS06440
uniprot id: F6CW20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

491952:MAR181 RS04095
gene id: 491952:MAR181_RS04095
uniprot id: F6CS67
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

491952:MAR181 RS00915
gene id: 491952:MAR181_RS00915
uniprot id: F6CWZ7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS09780
gene id: 491952:MAR181_RS09780
uniprot id: F6CRV1
names: Subcellular Location Annotation
messages: Cell inner membrane

491952:MAR181 RS17015
gene id: 491952:MAR181_RS17015
uniprot id: F6CUF0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

491952:MAR181 RS11770
gene id: 491952:MAR181_RS11770
uniprot id: F6CVG7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS17325
gene id: 491952:MAR181_RS17325
uniprot id: F6CUK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

491952:MAR181 RS04225
gene id: 491952:MAR181_RS04225
uniprot id: F6CS92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

491952:MAR181 RS12095
gene id: 491952:MAR181_RS12095
uniprot id: F6CW48
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS00195
gene id: 491952:MAR181_RS00195
uniprot id: F6CYY0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS03635
gene id: 491952:MAR181_RS03635
uniprot id: F6CRK5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

491952:MAR181 RS15175
gene id: 491952:MAR181_RS15175
uniprot id: F6D1C2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

491952:MAR181 RS13510
gene id: 491952:MAR181_RS13510
uniprot id: F6CY50
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

491952:MAR181 RS05035
gene id: 491952:MAR181_RS05035
uniprot id: F6CTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

491952:MAR181 RS17985
gene id: 491952:MAR181_RS17985
uniprot id: F6CVT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS10800
gene id: 491952:MAR181_RS10800
uniprot id: F6CTN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS12430
gene id: 491952:MAR181_RS12430
uniprot id: F6CWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

491952:MAR181 RS17040
gene id: 491952:MAR181_RS17040
uniprot id: F6CUF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

491952:MAR181 RS04300
gene id: 491952:MAR181_RS04300
uniprot id: F6CSA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

491952:MAR181 RS06305
gene id: 491952:MAR181_RS06305
uniprot id: F6CVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

491952:MAR181 RS04490
gene id: 491952:MAR181_RS04490
uniprot id: F6CSU2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

491952:MAR181 RS14170
gene id: 491952:MAR181_RS14170
uniprot id: F6CZK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

491952:MAR181 RS16735
gene id: 491952:MAR181_RS16735
uniprot id: F6CTU5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

491952:MAR181 RS00655
gene id: 491952:MAR181_RS00655
uniprot id: F6CWE4
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS13900
gene id: 491952:MAR181_RS13900
uniprot id: F6CYS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS16975
gene id: 491952:MAR181_RS16975
uniprot id: F6CUE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

491952:MAR181 RS00505
gene id: 491952:MAR181_RS00505
uniprot id: F6CVW1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

491952:MAR181 RS04965
gene id: 491952:MAR181_RS04965
uniprot id: F6CTH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

491952:MAR181 RS09725
gene id: 491952:MAR181_RS09725
uniprot id: F6CRU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

491952:MAR181 RS01270
gene id: 491952:MAR181_RS01270
uniprot id: F6CX68
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

491952:MAR181 RS01865
gene id: 491952:MAR181_RS01865
uniprot id: F6CYB4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS04955
gene id: 491952:MAR181_RS04955
uniprot id: F6CTH1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

491952:MAR181 RS04295
gene id: 491952:MAR181_RS04295
uniprot id: F6CSA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

491952:MAR181 RS13280
gene id: 491952:MAR181_RS13280
uniprot id: F6CY04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

491952:MAR181 RS09750
gene id: 491952:MAR181_RS09750
uniprot id: F6CRU5
names: Similarity
messages: Belongs to the elongation factor P family.

491952:MAR181 RS16350
gene id: 491952:MAR181_RS16350
uniprot id: F6CT80
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

491952:MAR181 RS17980
gene id: 491952:MAR181_RS17980
uniprot id: F6CVT2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

491952:MAR181 RS03010
gene id: 491952:MAR181_RS03010
uniprot id: F6D0D3
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS05260
gene id: 491952:MAR181_RS05260
uniprot id: F6CU29
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

491952:MAR181 RS07440
gene id: 491952:MAR181_RS07440
uniprot id: F6CXV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS05040
gene id: 491952:MAR181_RS05040
uniprot id: F6CTI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

491952:MAR181 RS05460
gene id: 491952:MAR181_RS05460
uniprot id: F6CUL3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

491952:MAR181 RS00020
gene id: 491952:MAR181_RS00020
uniprot id: F6CYU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

491952:MAR181 RS16995
gene id: 491952:MAR181_RS16995
uniprot id: F6CUE6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

491952:MAR181 RS00885
gene id: 491952:MAR181_RS00885
uniprot id: F6CWJ0
names: Similarity
messages: Belongs to the peptidase A24 family.

491952:MAR181 RS13775
gene id: 491952:MAR181_RS13775
uniprot id: F6CYQ3
names: Similarity
messages: Belongs to the MotB family.

491952:MAR181 RS14845
gene id: 491952:MAR181_RS14845
uniprot id: F6D0R3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS12940
gene id: 491952:MAR181_RS12940
uniprot id: F6CXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

491952:MAR181 RS12375
gene id: 491952:MAR181_RS12375
uniprot id: F6CWA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

491952:MAR181 RS16950
gene id: 491952:MAR181_RS16950
uniprot id: F6CTY8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

491952:MAR181 RS07055
gene id: 491952:MAR181_RS07055
uniprot id: F6CX88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

491952:MAR181 RS07340
gene id: 491952:MAR181_RS07340
uniprot id: F6CXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS02175
gene id: 491952:MAR181_RS02175
uniprot id: F6CZ46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

491952:MAR181 RS11205
gene id: 491952:MAR181_RS11205
uniprot id: F6CUB1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

491952:MAR181 RS08915
gene id: 491952:MAR181_RS08915
uniprot id: F6D0I4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

491952:MAR181 RS16535
gene id: 491952:MAR181_RS16535
uniprot id: F6CTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

491952:MAR181 RS14135
gene id: 491952:MAR181_RS14135
uniprot id: F6CZJ6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

491952:MAR181 RS10960
gene id: 491952:MAR181_RS10960
uniprot id: F6CTR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

491952:MAR181 RS09405
gene id: 491952:MAR181_RS09405
uniprot id: F6D172
names: Similarity
messages: Belongs to the xylose isomerase family.

491952:MAR181 RS06490
gene id: 491952:MAR181_RS06490
uniprot id: F6CW30
names: Similarity
messages: Belongs to the DinB family.

491952:MAR181 RS11045
gene id: 491952:MAR181_RS11045
uniprot id: F6CU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS04380
gene id: 491952:MAR181_RS04380
uniprot id: F6CSS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

491952:MAR181 RS10050
gene id: 491952:MAR181_RS10050
uniprot id: F6CSF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS08660
gene id: 491952:MAR181_RS08660
uniprot id: F6CZZ1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

491952:MAR181 RS14985
gene id: 491952:MAR181_RS14985
uniprot id: F6D0U1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

491952:MAR181 RS06405
gene id: 491952:MAR181_RS06405
uniprot id: F6CW13
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

491952:MAR181 RS01775
gene id: 491952:MAR181_RS01775
uniprot id: F6CY96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

491952:MAR181 RS14300
gene id: 491952:MAR181_RS14300
uniprot id: F6CZM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS15315
gene id: 491952:MAR181_RS15315
uniprot id: F6D1F0
names: Similarity
messages: Belongs to the TrpR family.

491952:MAR181 RS14620
gene id: 491952:MAR181_RS14620
uniprot id: F6D077
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

491952:MAR181 RS04360
gene id: 491952:MAR181_RS04360
uniprot id: F6CSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

491952:MAR181 RS01995
gene id: 491952:MAR181_RS01995
uniprot id: F6CYE0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

491952:MAR181 RS06910
gene id: 491952:MAR181_RS06910
uniprot id: F6CWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

491952:MAR181 RS01510
gene id: 491952:MAR181_RS01510
uniprot id: F6CXQ8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

491952:MAR181 RS06220
gene id: 491952:MAR181_RS06220
uniprot id: F6CVX6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

491952:MAR181 RS02340
gene id: 491952:MAR181_RS02340
uniprot id: F6CZ79
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS06120
gene id: 491952:MAR181_RS06120
uniprot id: F6CVE6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

491952:MAR181 RS02565
gene id: 491952:MAR181_RS02565
uniprot id: F6CZR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

491952:MAR181 RS13965
gene id: 491952:MAR181_RS13965
uniprot id: F6CYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

491952:MAR181 RS00470
gene id: 491952:MAR181_RS00470
uniprot id: F6CVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS08715
gene id: 491952:MAR181_RS08715
uniprot id: F6D002
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

491952:MAR181 RS00150
gene id: 491952:MAR181_RS00150
uniprot id: F6CYX1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

491952:MAR181 RS16510
gene id: 491952:MAR181_RS16510
uniprot id: F6CTA9
names: Similarity
messages: Belongs to the SfsA family.

491952:MAR181 RS02350
gene id: 491952:MAR181_RS02350
uniprot id: F6CZ81
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

491952:MAR181 RS09655
gene id: 491952:MAR181_RS09655
uniprot id: F6CRS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS03515
gene id: 491952:MAR181_RS03515
uniprot id: F6D126
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

491952:MAR181 RS13565
gene id: 491952:MAR181_RS13565
uniprot id: F6CY61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

491952:MAR181 RS17075
gene id: 491952:MAR181_RS17075
uniprot id: F6CUG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

491952:MAR181 RS09825
gene id: 491952:MAR181_RS09825
uniprot id: F6CRW0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

491952:MAR181 RS00425
gene id: 491952:MAR181_RS00425
uniprot id: F6CVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS15460
gene id: 491952:MAR181_RS15460
uniprot id: F6D1H8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

491952:MAR181 RS10220
gene id: 491952:MAR181_RS10220
uniprot id: F6CSI7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

491952:MAR181 RS11525
gene id: 491952:MAR181_RS11525
uniprot id: F6CUW7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS08000
gene id: 491952:MAR181_RS08000
uniprot id: F6CYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

491952:MAR181 RS00520
gene id: 491952:MAR181_RS00520
uniprot id: F6CVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

491952:MAR181 RS03175
gene id: 491952:MAR181_RS03175
uniprot id: F6D0G6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS13225
gene id: 491952:MAR181_RS13225
uniprot id: F6CXK9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS16195
gene id: 491952:MAR181_RS16195
uniprot id: F6CSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

491952:MAR181 RS09975
gene id: 491952:MAR181_RS09975
uniprot id: F6CSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

491952:MAR181 RS07455
gene id: 491952:MAR181_RS07455
uniprot id: F6CXV7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

491952:MAR181 RS04465
gene id: 491952:MAR181_RS04465
uniprot id: F6CST7
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

491952:MAR181 RS07470
gene id: 491952:MAR181_RS07470
uniprot id: F6CXW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

491952:MAR181 RS04480
gene id: 491952:MAR181_RS04480
uniprot id: F6CSU0
names: Similarity
messages: Belongs to the CobH/CbiC family.

491952:MAR181 RS08920
gene id: 491952:MAR181_RS08920
uniprot id: F6D0I5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

491952:MAR181 RS10310
gene id: 491952:MAR181_RS10310
uniprot id: F6CT01
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

491952:MAR181 RS11990
gene id: 491952:MAR181_RS11990
uniprot id: F6CVL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS07275
gene id: 491952:MAR181_RS07275
uniprot id: F6CXD1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

491952:MAR181 RS10765
gene id: 491952:MAR181_RS10765
uniprot id: F6CTM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

491952:MAR181 RS14070
gene id: 491952:MAR181_RS14070
uniprot id: F6CZI3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

491952:MAR181 RS01845
gene id: 491952:MAR181_RS01845
uniprot id: F6CYB0
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

491952:MAR181 RS04610
gene id: 491952:MAR181_RS04610
uniprot id: F6CSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS06355
gene id: 491952:MAR181_RS06355
uniprot id: F6CW03
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

491952:MAR181 RS09255
gene id: 491952:MAR181_RS09255
uniprot id: F6D141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS12030
gene id: 491952:MAR181_RS12030
uniprot id: F6CVL9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

491952:MAR181 RS14225
gene id: 491952:MAR181_RS14225
uniprot id: F6CZL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

491952:MAR181 RS01890
gene id: 491952:MAR181_RS01890
uniprot id: F6CYB9
names: Similarity
messages: Belongs to the PrpF family.

491952:MAR181 RS06100
gene id: 491952:MAR181_RS06100
uniprot id: F6CVE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

491952:MAR181 RS02190
gene id: 491952:MAR181_RS02190
uniprot id: F6CZ49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

491952:MAR181 RS00190
gene id: 491952:MAR181_RS00190
uniprot id: F6CYX9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS04005
gene id: 491952:MAR181_RS04005
uniprot id: F6CS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

491952:MAR181 RS15115
gene id: 491952:MAR181_RS15115
uniprot id: F6D1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

491952:MAR181 RS07585
gene id: 491952:MAR181_RS07585
uniprot id: F6CXW7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

491952:MAR181 RS13830
gene id: 491952:MAR181_RS13830
uniprot id: F6CYR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS13345
gene id: 491952:MAR181_RS13345
uniprot id: F6CY17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

491952:MAR181 RS14700
gene id: 491952:MAR181_RS14700
uniprot id: F6D092
names: Similarity
messages: Belongs to the citrate synthase family.

491952:MAR181 RS10555
gene id: 491952:MAR181_RS10555
uniprot id: F6CT44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS12500
gene id: 491952:MAR181_RS12500
uniprot id: F6CWS7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

491952:MAR181 RS12380
gene id: 491952:MAR181_RS12380
uniprot id: F6CWA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

491952:MAR181 RS08940
gene id: 491952:MAR181_RS08940
uniprot id: F6D0I9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

491952:MAR181 RS11875
gene id: 491952:MAR181_RS11875
uniprot id: F6CVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

491952:MAR181 RS07205
gene id: 491952:MAR181_RS07205
uniprot id: F6CXB7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

491952:MAR181 RS07320
gene id: 491952:MAR181_RS07320
uniprot id: F6CXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

491952:MAR181 RS13990
gene id: 491952:MAR181_RS13990
uniprot id: F6CZG7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

491952:MAR181 RS13355
gene id: 491952:MAR181_RS13355
uniprot id: F6CY19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

491952:MAR181 RS15770
gene id: 491952:MAR181_RS15770
uniprot id: F6CS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS06210
gene id: 491952:MAR181_RS06210
uniprot id: F6CVX4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

491952:MAR181 RS11095
gene id: 491952:MAR181_RS11095
uniprot id: F6CU89
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS08025
gene id: 491952:MAR181_RS08025
uniprot id: F6CYL0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS14660
gene id: 491952:MAR181_RS14660
uniprot id: F6D084
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS00810
gene id: 491952:MAR181_RS00810
uniprot id: F6CWH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

491952:MAR181 RS01330
gene id: 491952:MAR181_RS01330
uniprot id: F6CXM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

491952:MAR181 RS15800
gene id: 491952:MAR181_RS15800
uniprot id: F6CS29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS16820
gene id: 491952:MAR181_RS16820
uniprot id: F6CTW2
names: Similarity
messages: Belongs to the peptidase M16 family.

491952:MAR181 RS10825
gene id: 491952:MAR181_RS10825
uniprot id: F6CTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS07705
gene id: 491952:MAR181_RS07705
uniprot id: F6CXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

491952:MAR181 RS08770
gene id: 491952:MAR181_RS08770
uniprot id: F6D013
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

491952:MAR181 RS16910
gene id: 491952:MAR181_RS16910
uniprot id: F6CTY0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

491952:MAR181 RS00385
gene id: 491952:MAR181_RS00385
uniprot id: F6CVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

491952:MAR181 RS01585
gene id: 491952:MAR181_RS01585
uniprot id: F6CXS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS15670
gene id: 491952:MAR181_RS15670
uniprot id: F6CS02
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS02165
gene id: 491952:MAR181_RS02165
uniprot id: F6CZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

491952:MAR181 RS13260
gene id: 491952:MAR181_RS13260
uniprot id: F6CY00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

491952:MAR181 RS13550
gene id: 491952:MAR181_RS13550
uniprot id: F6CY58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

491952:MAR181 RS05190
gene id: 491952:MAR181_RS05190
uniprot id: F6CU14
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS05000
gene id: 491952:MAR181_RS05000
uniprot id: F6CTI0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

491952:MAR181 RS00675
gene id: 491952:MAR181_RS00675
uniprot id: F6CWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS13240
gene id: 491952:MAR181_RS13240
uniprot id: F6CXZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

491952:MAR181 RS02140
gene id: 491952:MAR181_RS02140
uniprot id: F6CZ39
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

491952:MAR181 RS15395
gene id: 491952:MAR181_RS15395
uniprot id: F6D1G5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS08765
gene id: 491952:MAR181_RS08765
uniprot id: F6D012
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

491952:MAR181 RS09395
gene id: 491952:MAR181_RS09395
uniprot id: F6D170
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS01765
gene id: 491952:MAR181_RS01765
uniprot id: F6CY94
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

491952:MAR181 RS05585
gene id: 491952:MAR181_RS05585
uniprot id: F6CUP0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

491952:MAR181 RS07345
gene id: 491952:MAR181_RS07345
uniprot id: F6CXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

491952:MAR181 RS07010
gene id: 491952:MAR181_RS07010
uniprot id: F6CX79
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

491952:MAR181 RS11275
gene id: 491952:MAR181_RS11275
uniprot id: F6CUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

491952:MAR181 RS02645
gene id: 491952:MAR181_RS02645
uniprot id: F6CZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

491952:MAR181 RS14415
gene id: 491952:MAR181_RS14415
uniprot id: F6D038
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

491952:MAR181 RS09250
gene id: 491952:MAR181_RS09250
uniprot id: F6D140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS17945
gene id: 491952:MAR181_RS17945
uniprot id: F6CVS5
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS15095
gene id: 491952:MAR181_RS15095
uniprot id: F6D0W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

491952:MAR181 RS14075
gene id: 491952:MAR181_RS14075
uniprot id: F6CZI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

491952:MAR181 RS10025
gene id: 491952:MAR181_RS10025
uniprot id: F6CSE8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

491952:MAR181 RS09295
gene id: 491952:MAR181_RS09295
uniprot id: F6D150
names: Subcellular Location Annotation
messages: Cytoplasm

491952:MAR181 RS00160
gene id: 491952:MAR181_RS00160
uniprot id: F6CYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS11210
gene id: 491952:MAR181_RS11210
uniprot id: F6CUB2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

491952:MAR181 RS01260
gene id: 491952:MAR181_RS01260
uniprot id: F6CX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

491952:MAR181 RS17380
gene id: 491952:MAR181_RS17380
uniprot id: F6CV16
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS12470
gene id: 491952:MAR181_RS12470
uniprot id: F6CWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

491952:MAR181 RS03855
gene id: 491952:MAR181_RS03855
uniprot id: F6CRP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

491952:MAR181 RS03490
gene id: 491952:MAR181_RS03490
uniprot id: F6D121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

491952:MAR181 RS11240
gene id: 491952:MAR181_RS11240
uniprot id: F6CUB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

491952:MAR181 RS14385
gene id: 491952:MAR181_RS14385
uniprot id: F6D032
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

491952:MAR181 RS04420
gene id: 491952:MAR181_RS04420
uniprot id: F6CSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

491952:MAR181 RS02665
gene id: 491952:MAR181_RS02665
uniprot id: F6CZT9
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS03035
gene id: 491952:MAR181_RS03035
uniprot id: F6D0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

491952:MAR181 RS01760
gene id: 491952:MAR181_RS01760
uniprot id: F6CY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

491952:MAR181 RS13230
gene id: 491952:MAR181_RS13230
uniprot id: F6CXZ4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

491952:MAR181 RS08655
gene id: 491952:MAR181_RS08655
uniprot id: F6CZZ0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

491952:MAR181 RS00450
gene id: 491952:MAR181_RS00450
uniprot id: F6CVV0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS14425
gene id: 491952:MAR181_RS14425
uniprot id: F6D040
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS00175
gene id: 491952:MAR181_RS00175
uniprot id: F6CYX6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

491952:MAR181 RS11905
gene id: 491952:MAR181_RS11905
uniprot id: F6CVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS10770
gene id: 491952:MAR181_RS10770
uniprot id: F6CTM8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

491952:MAR181 RS04130
gene id: 491952:MAR181_RS04130
uniprot id: F6CS73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

491952:MAR181 RS12915
gene id: 491952:MAR181_RS12915
uniprot id: F6CXF5
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS16930
gene id: 491952:MAR181_RS16930
uniprot id: F6CTY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

491952:MAR181 RS13040
gene id: 491952:MAR181_RS13040
uniprot id: F6CXH6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

491952:MAR181 RS16000
gene id: 491952:MAR181_RS16000
uniprot id: F6CSL7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS00060
gene id: 491952:MAR181_RS00060
uniprot id: F6CYV3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

491952:MAR181 RS12955
gene id: 491952:MAR181_RS12955
uniprot id: F6CXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

491952:MAR181 RS01360
gene id: 491952:MAR181_RS01360
uniprot id: F6CXM7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

491952:MAR181 RS08285
gene id: 491952:MAR181_RS08285
uniprot id: F6CZD4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

491952:MAR181 RS07630
gene id: 491952:MAR181_RS07630
uniprot id: F6CXX6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS03870
gene id: 491952:MAR181_RS03870
uniprot id: F6CRP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

491952:MAR181 RS17480
gene id: 491952:MAR181_RS17480
uniprot id: F6CV36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

491952:MAR181 RS13840
gene id: 491952:MAR181_RS13840
uniprot id: F6CYR6
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

491952:MAR181 RS16750
gene id: 491952:MAR181_RS16750
uniprot id: F6CTU8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

491952:MAR181 RS12765
gene id: 491952:MAR181_RS12765
uniprot id: F6CWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS17100
gene id: 491952:MAR181_RS17100
uniprot id: F6CUG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS12405
gene id: 491952:MAR181_RS12405
uniprot id: F6CWA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS01525
gene id: 491952:MAR181_RS01525
uniprot id: F6CXR1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

491952:MAR181 RS15960
gene id: 491952:MAR181_RS15960
uniprot id: F6CSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

491952:MAR181 RS06135
gene id: 491952:MAR181_RS06135
uniprot id: F6CVE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS03940
gene id: 491952:MAR181_RS03940
uniprot id: F6CRR0
names: Similarity
messages: Belongs to the TlyA family.

491952:MAR181 RS01830
gene id: 491952:MAR181_RS01830
uniprot id: F6CYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS15695
gene id: 491952:MAR181_RS15695
uniprot id: F6CS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS16210
gene id: 491952:MAR181_RS16210
uniprot id: F6CSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS02415
gene id: 491952:MAR181_RS02415
uniprot id: F6CZN9
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS14140
gene id: 491952:MAR181_RS14140
uniprot id: F6CZJ7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

491952:MAR181 RS17010
gene id: 491952:MAR181_RS17010
uniprot id: F6CUE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

491952:MAR181 RS05125
gene id: 491952:MAR181_RS05125
uniprot id: F6CU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

491952:MAR181 RS15390
gene id: 491952:MAR181_RS15390
uniprot id: F6D1G4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS08670
gene id: 491952:MAR181_RS08670
uniprot id: F6CZZ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

491952:MAR181 RS13975
gene id: 491952:MAR181_RS13975
uniprot id: F6CZG4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

491952:MAR181 RS14400
gene id: 491952:MAR181_RS14400
uniprot id: F6D035
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

491952:MAR181 RS04425
gene id: 491952:MAR181_RS04425
uniprot id: F6CSS9
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

491952:MAR181 RS10525
gene id: 491952:MAR181_RS10525
uniprot id: F6CT37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

491952:MAR181 RS03770
gene id: 491952:MAR181_RS03770
uniprot id: F6CRM7
names: Similarity
messages: Belongs to the pirin family.

491952:MAR181 RS00610
gene id: 491952:MAR181_RS00610
uniprot id: F6CWD5
names: Caution
names: Function
names: Similarity
messages: As this bacterium is not an Enterobacterale, this protein may not have a true dGTPase activity.
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

491952:MAR181 RS14280
gene id: 491952:MAR181_RS14280
uniprot id: F6CZM4
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

491952:MAR181 RS17625
gene id: 491952:MAR181_RS17625
uniprot id: F6CV65
names: Similarity
messages: Belongs to the RutC family.

491952:MAR181 RS05765
gene id: 491952:MAR181_RS05765
uniprot id: F6CUS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

491952:MAR181 RS01345
gene id: 491952:MAR181_RS01345
uniprot id: F6CXM4
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS06545
gene id: 491952:MAR181_RS06545
uniprot id: F6CW41
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

491952:MAR181 RS15440
gene id: 491952:MAR181_RS15440
uniprot id: F6D1H4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

491952:MAR181 RS14765
gene id: 491952:MAR181_RS14765
uniprot id: F6D0P7
names: Similarity
messages: Belongs to the DapA family.

491952:MAR181 RS09450
gene id: 491952:MAR181_RS09450
uniprot id: F6D181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS12950
gene id: 491952:MAR181_RS12950
uniprot id: F6CXG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

491952:MAR181 RS13505
gene id: 491952:MAR181_RS13505
uniprot id: F6CY49
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

491952:MAR181 RS16390
gene id: 491952:MAR181_RS16390
uniprot id: F6CT88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

491952:MAR181 RS06330
gene id: 491952:MAR181_RS06330
uniprot id: F6CVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS15050
gene id: 491952:MAR181_RS15050
uniprot id: F6D0V4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

491952:MAR181 RS00275
gene id: 491952:MAR181_RS00275
uniprot id: F6CYZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS08370
gene id: 491952:MAR181_RS08370
uniprot id: F6CZF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

491952:MAR181 RS09040
gene id: 491952:MAR181_RS09040
uniprot id: F6D0K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

491952:MAR181 RS10425
gene id: 491952:MAR181_RS10425
uniprot id: F6CT18
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS11795
gene id: 491952:MAR181_RS11795
uniprot id: F6CVH2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS12355
gene id: 491952:MAR181_RS12355
uniprot id: F6CW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

491952:MAR181 RS17995
gene id: 491952:MAR181_RS17995
uniprot id: F6CVT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

491952:MAR181 RS08295
gene id: 491952:MAR181_RS08295
uniprot id: F6CZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

491952:MAR181 RS17615
gene id: 491952:MAR181_RS17615
uniprot id: F6CV63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

491952:MAR181 RS13145
gene id: 491952:MAR181_RS13145
uniprot id: F6CXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

491952:MAR181 RS03440
gene id: 491952:MAR181_RS03440
uniprot id: F6D114
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

491952:MAR181 RS06960
gene id: 491952:MAR181_RS06960
uniprot id: F6CX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS11855
gene id: 491952:MAR181_RS11855
uniprot id: F6CVI3
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS15965
gene id: 491952:MAR181_RS15965
uniprot id: F6CSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

491952:MAR181 RS00120
gene id: 491952:MAR181_RS00120
uniprot id: F6CYW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS13485
gene id: 491952:MAR181_RS13485
uniprot id: F6CY45
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

491952:MAR181 RS03555
gene id: 491952:MAR181_RS03555
uniprot id: F6D129
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

491952:MAR181 RS14485
gene id: 491952:MAR181_RS14485
uniprot id: F6D052
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

491952:MAR181 RS06190
gene id: 491952:MAR181_RS06190
uniprot id: F6CVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

491952:MAR181 RS13015
gene id: 491952:MAR181_RS13015
uniprot id: F6CXH4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

491952:MAR181 RS17770
gene id: 491952:MAR181_RS17770
uniprot id: F6CVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

491952:MAR181 RS12865
gene id: 491952:MAR181_RS12865
uniprot id: F6CXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS03660
gene id: 491952:MAR181_RS03660
uniprot id: F6CRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS02600
gene id: 491952:MAR181_RS02600
uniprot id: F6CZS6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

491952:MAR181 RS05535
gene id: 491952:MAR181_RS05535
uniprot id: F6CUM9
names: Similarity
messages: Belongs to the GST superfamily.

491952:MAR181 RS05135
gene id: 491952:MAR181_RS05135
uniprot id: F6CU02
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

491952:MAR181 RS05065
gene id: 491952:MAR181_RS05065
uniprot id: F6CTJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

491952:MAR181 RS02215
gene id: 491952:MAR181_RS02215
uniprot id: F6CZ54
names: Similarity
messages: Belongs to the LacAB/RpiB family.

491952:MAR181 RS00090
gene id: 491952:MAR181_RS00090
uniprot id: F6CYV9
names: Similarity
messages: Belongs to the DprA/Smf family.

491952:MAR181 RS06400
gene id: 491952:MAR181_RS06400
uniprot id: F6CW12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

491952:MAR181 RS08545
gene id: 491952:MAR181_RS08545
uniprot id: F6CZY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS02345
gene id: 491952:MAR181_RS02345
uniprot id: F6CZ80
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

491952:MAR181 RS02030
gene id: 491952:MAR181_RS02030
uniprot id: F6CZ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

491952:MAR181 RS12390
gene id: 491952:MAR181_RS12390
uniprot id: F6CWA6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

491952:MAR181 RS05120
gene id: 491952:MAR181_RS05120
uniprot id: F6CTZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS11175
gene id: 491952:MAR181_RS11175
uniprot id: F6CUA5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS17835
gene id: 491952:MAR181_RS17835
uniprot id: F6CVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

491952:MAR181 RS01450
gene id: 491952:MAR181_RS01450
uniprot id: F6CXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS05165
gene id: 491952:MAR181_RS05165
uniprot id: F6CU08
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

491952:MAR181 RS02125
gene id: 491952:MAR181_RS02125
uniprot id: F6CZ36
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

491952:MAR181 RS13650
gene id: 491952:MAR181_RS13650
uniprot id: F6CYM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS17340
gene id: 491952:MAR181_RS17340
uniprot id: F6CUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

491952:MAR181 RS00995
gene id: 491952:MAR181_RS00995
uniprot id: F6CX14
names: Similarity
messages: Belongs to the nitroreductase family.

491952:MAR181 RS13875
gene id: 491952:MAR181_RS13875
uniprot id: F6CYS3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

491952:MAR181 RS08700
gene id: 491952:MAR181_RS08700
uniprot id: F6CZZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

491952:MAR181 RS01210
gene id: 491952:MAR181_RS01210
uniprot id: F6CX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS00135
gene id: 491952:MAR181_RS00135
uniprot id: F6CYW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS10170
gene id: 491952:MAR181_RS10170
uniprot id: F6CSH7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

491952:MAR181 RS16770
gene id: 491952:MAR181_RS16770
uniprot id: F6CTV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

491952:MAR181 RS09985
gene id: 491952:MAR181_RS09985
uniprot id: F6CSE0
names: Similarity
messages: Belongs to the UPF0102 family.

491952:MAR181 RS14705
gene id: 491952:MAR181_RS14705
uniprot id: F6D093
names: Similarity
messages: Belongs to the PrpD family.

491952:MAR181 RS12465
gene id: 491952:MAR181_RS12465
uniprot id: F6CWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

491952:MAR181 RS15080
gene id: 491952:MAR181_RS15080
uniprot id: F6D0W0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS13675
gene id: 491952:MAR181_RS13675
uniprot id: F6CYN3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

491952:MAR181 RS12975
gene id: 491952:MAR181_RS12975
uniprot id: F6CXG6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

491952:MAR181 RS13460
gene id: 491952:MAR181_RS13460
uniprot id: F6CY40
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

491952:MAR181 RS02240
gene id: 491952:MAR181_RS02240
uniprot id: F6CZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

491952:MAR181 RS03605
gene id: 491952:MAR181_RS03605
uniprot id: F6CRJ9
names: Similarity
messages: Belongs to the UPF0246 family.

491952:MAR181 RS00065
gene id: 491952:MAR181_RS00065
uniprot id: F6CYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS06215
gene id: 491952:MAR181_RS06215
uniprot id: F6CVX5
names: Similarity
messages: Belongs to the UPF0250 family.

491952:MAR181 RS16090
gene id: 491952:MAR181_RS16090
uniprot id: F6CSN4
names: Similarity
messages: Belongs to the CFA/CMAS family.

491952:MAR181 RS14880
gene id: 491952:MAR181_RS14880
uniprot id: F6D0S0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

491952:MAR181 RS13490
gene id: 491952:MAR181_RS13490
uniprot id: F6CY46
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS13720
gene id: 491952:MAR181_RS13720
uniprot id: F6CYP2
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

491952:MAR181 RS01780
gene id: 491952:MAR181_RS01780
uniprot id: F6CY97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS00010
gene id: 491952:MAR181_RS00010
uniprot id: F6CYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

491952:MAR181 RS02085
gene id: 491952:MAR181_RS02085
uniprot id: F6CZ28
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

491952:MAR181 RS02965
gene id: 491952:MAR181_RS02965
uniprot id: F6D0C5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

491952:MAR181 RS14480
gene id: 491952:MAR181_RS14480
uniprot id: F6D051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

491952:MAR181 RS02730
gene id: 491952:MAR181_RS02730
uniprot id: F6CZV1
names: Subunit
messages: Monomer.

491952:MAR181 RS04710
gene id: 491952:MAR181_RS04710
uniprot id: F6CSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS17550
gene id: 491952:MAR181_RS17550
uniprot id: F6CV50
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS17455
gene id: 491952:MAR181_RS17455
uniprot id: F6CV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS06250
gene id: 491952:MAR181_RS06250
uniprot id: F6CVY2
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

491952:MAR181 RS11290
gene id: 491952:MAR181_RS11290
uniprot id: F6CUC8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS09070
gene id: 491952:MAR181_RS09070
uniprot id: F6D0L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

491952:MAR181 RS06930
gene id: 491952:MAR181_RS06930
uniprot id: F6CWR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

491952:MAR181 RS14055
gene id: 491952:MAR181_RS14055
uniprot id: F6CZI0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

491952:MAR181 RS10700
gene id: 491952:MAR181_RS10700
uniprot id: F6CTL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

491952:MAR181 RS09815
gene id: 491952:MAR181_RS09815
uniprot id: F6CRV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

491952:MAR181 RS17070
gene id: 491952:MAR181_RS17070
uniprot id: F6CUG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

491952:MAR181 RS17060
gene id: 491952:MAR181_RS17060
uniprot id: F6CUF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

491952:MAR181 RS15455
gene id: 491952:MAR181_RS15455
uniprot id: F6D1H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

491952:MAR181 RS03595
gene id: 491952:MAR181_RS03595
uniprot id: F6CRJ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

491952:MAR181 RS11805
gene id: 491952:MAR181_RS11805
uniprot id: F6CVH4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS02635
gene id: 491952:MAR181_RS02635
uniprot id: F6CZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS03740
gene id: 491952:MAR181_RS03740
uniprot id: F6CRM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS10935
gene id: 491952:MAR181_RS10935
uniprot id: F6CTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS17845
gene id: 491952:MAR181_RS17845
uniprot id: F6CVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

491952:MAR181 RS06140
gene id: 491952:MAR181_RS06140
uniprot id: F6CVE9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

491952:MAR181 RS16605
gene id: 491952:MAR181_RS16605
uniprot id: F6CTS5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS09050
gene id: 491952:MAR181_RS09050
uniprot id: F6D0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS17305
gene id: 491952:MAR181_RS17305
uniprot id: F6CUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

491952:MAR181 RS07180
gene id: 491952:MAR181_RS07180
uniprot id: F6CXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

491952:MAR181 RS05270
gene id: 491952:MAR181_RS05270
uniprot id: F6CU31
names: Subcellular Location Annotation
messages: Cell inner membrane

491952:MAR181 RS04325
gene id: 491952:MAR181_RS04325
uniprot id: F6CSB2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

491952:MAR181 RS00340
gene id: 491952:MAR181_RS00340
uniprot id: F6CZ09
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS16780
gene id: 491952:MAR181_RS16780
uniprot id: F6CTV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

491952:MAR181 RS04040
gene id: 491952:MAR181_RS04040
uniprot id: F6CS56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

491952:MAR181 RS04900
gene id: 491952:MAR181_RS04900
uniprot id: F6CTG0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

491952:MAR181 RS13325
gene id: 491952:MAR181_RS13325
uniprot id: F6CY13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

491952:MAR181 RS09580
gene id: 491952:MAR181_RS09580
uniprot id: F6D1A7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS08180
gene id: 491952:MAR181_RS08180
uniprot id: F6CZB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

491952:MAR181 RS17950
gene id: 491952:MAR181_RS17950
uniprot id: F6CVS6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

491952:MAR181 RS13395
gene id: 491952:MAR181_RS13395
uniprot id: F6CY27
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS06895
gene id: 491952:MAR181_RS06895
uniprot id: F6CWQ9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

491952:MAR181 RS16375
gene id: 491952:MAR181_RS16375
uniprot id: F6CT85
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

491952:MAR181 RS09540
gene id: 491952:MAR181_RS09540
uniprot id: F6D199
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

491952:MAR181 RS06155
gene id: 491952:MAR181_RS06155
uniprot id: F6CVF2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

491952:MAR181 RS08210
gene id: 491952:MAR181_RS08210
uniprot id: F6CZB9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

491952:MAR181 RS06030
gene id: 491952:MAR181_RS06030
uniprot id: F6CVC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS08810
gene id: 491952:MAR181_RS08810
uniprot id: F6D021
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS12485
gene id: 491952:MAR181_RS12485
uniprot id: F6CWS4
names: Similarity
messages: Belongs to the HesB/IscA family.

491952:MAR181 RS16410
gene id: 491952:MAR181_RS16410
uniprot id: F6CT92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

491952:MAR181 RS15795
gene id: 491952:MAR181_RS15795
uniprot id: F6CS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS12875
gene id: 491952:MAR181_RS12875
uniprot id: F6CXE7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

491952:MAR181 RS01365
gene id: 491952:MAR181_RS01365
uniprot id: F6CXM8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

491952:MAR181 RS07850
gene id: 491952:MAR181_RS07850
uniprot id: F6CYH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

491952:MAR181 RS03695
gene id: 491952:MAR181_RS03695
uniprot id: F6CRL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

491952:MAR181 RS01535
gene id: 491952:MAR181_RS01535
uniprot id: F6CXR3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS11350
gene id: 491952:MAR181_RS11350
uniprot id: F6CUE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS09610
gene id: 491952:MAR181_RS09610
uniprot id: F6CRR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03850
gene id: 491952:MAR181_RS03850
uniprot id: F6CRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS17295
gene id: 491952:MAR181_RS17295
uniprot id: F6CUJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

491952:MAR181 RS02640
gene id: 491952:MAR181_RS02640
uniprot id: F6CZT4
names: Similarity
messages: Belongs to the P(II) protein family.

491952:MAR181 RS04440
gene id: 491952:MAR181_RS04440
uniprot id: F6CST2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS02195
gene id: 491952:MAR181_RS02195
uniprot id: F6CZ50
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS05975
gene id: 491952:MAR181_RS05975
uniprot id: F6CVB7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS13220
gene id: 491952:MAR181_RS13220
uniprot id: F6CXK8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

491952:MAR181 RS11180
gene id: 491952:MAR181_RS11180
uniprot id: F6CUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

491952:MAR181 RS03860
gene id: 491952:MAR181_RS03860
uniprot id: F6CRP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS09480
gene id: 491952:MAR181_RS09480
uniprot id: F6D187
names: Similarity
messages: Belongs to the fabD family.

491952:MAR181 RS01080
gene id: 491952:MAR181_RS01080
uniprot id: F6CX31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS02135
gene id: 491952:MAR181_RS02135
uniprot id: F6CZ38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

491952:MAR181 RS04200
gene id: 491952:MAR181_RS04200
uniprot id: F6CS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

491952:MAR181 RS02225
gene id: 491952:MAR181_RS02225
uniprot id: F6CZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS02305
gene id: 491952:MAR181_RS02305
uniprot id: F6CZ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

491952:MAR181 RS02815
gene id: 491952:MAR181_RS02815
uniprot id: F6D0A4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS16055
gene id: 491952:MAR181_RS16055
uniprot id: F6CSM8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS07235
gene id: 491952:MAR181_RS07235
uniprot id: F6CXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS06420
gene id: 491952:MAR181_RS06420
uniprot id: F6CW16
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

491952:MAR181 RS16180
gene id: 491952:MAR181_RS16180
uniprot id: F6CSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

491952:MAR181 RS02855
gene id: 491952:MAR181_RS02855
uniprot id: F6D0B2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

491952:MAR181 RS09670
gene id: 491952:MAR181_RS09670
uniprot id: F6CRS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS11880
gene id: 491952:MAR181_RS11880
uniprot id: F6CVI8
names: Similarity
messages: Belongs to the phosphorylase b kinase regulatory chain family.

491952:MAR181 RS02535
gene id: 491952:MAR181_RS02535
uniprot id: F6CZR3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

491952:MAR181 RS14695
gene id: 491952:MAR181_RS14695
uniprot id: F6D091
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

491952:MAR181 RS10675
gene id: 491952:MAR181_RS10675
uniprot id: F6CTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

491952:MAR181 RS12385
gene id: 491952:MAR181_RS12385
uniprot id: F6CWA5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

491952:MAR181 RS15340
gene id: 491952:MAR181_RS15340
uniprot id: F6D1F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

491952:MAR181 RS13360
gene id: 491952:MAR181_RS13360
uniprot id: F6CY20
names: Similarity
messages: Belongs to the Skp family.

491952:MAR181 RS09585
gene id: 491952:MAR181_RS09585
uniprot id: F6D1A8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS06170
gene id: 491952:MAR181_RS06170
uniprot id: F6CVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

491952:MAR181 RS07390
gene id: 491952:MAR181_RS07390
uniprot id: F6CXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

491952:MAR181 RS17260
gene id: 491952:MAR181_RS17260
uniprot id: F6CUJ3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

491952:MAR181 RS04445
gene id: 491952:MAR181_RS04445
uniprot id: F6CST3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS10000
gene id: 491952:MAR181_RS10000
uniprot id: F6CSE3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

491952:MAR181 RS10070
gene id: 491952:MAR181_RS10070
uniprot id: F6CSF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

491952:MAR181 RS03055
gene id: 491952:MAR181_RS03055
uniprot id: F6D0E2
names: Similarity
messages: Belongs to the threonine synthase family.

491952:MAR181 RS09675
gene id: 491952:MAR181_RS09675
uniprot id: F6CRT0
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS08895
gene id: 491952:MAR181_RS08895
uniprot id: F6D0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

491952:MAR181 RS15295
gene id: 491952:MAR181_RS15295
uniprot id: F6D1E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS15055
gene id: 491952:MAR181_RS15055
uniprot id: F6D0V5
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

491952:MAR181 RS06110
gene id: 491952:MAR181_RS06110
uniprot id: F6CVE4
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

491952:MAR181 RS05340
gene id: 491952:MAR181_RS05340
uniprot id: F6CU46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

491952:MAR181 RS06175
gene id: 491952:MAR181_RS06175
uniprot id: F6CVF6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

491952:MAR181 RS17285
gene id: 491952:MAR181_RS17285
uniprot id: F6CUJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS03925
gene id: 491952:MAR181_RS03925
uniprot id: F6CRQ7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

491952:MAR181 RS05455
gene id: 491952:MAR181_RS05455
uniprot id: F6CUL2
names: Similarity
messages: Belongs to the GARS family.

491952:MAR181 RS16765
gene id: 491952:MAR181_RS16765
uniprot id: F6CTV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

491952:MAR181 RS09310
gene id: 491952:MAR181_RS09310
uniprot id: F6D153
names: Similarity
messages: Belongs to the peptidase M1 family.

491952:MAR181 RS08260
gene id: 491952:MAR181_RS08260
uniprot id: F6CZC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

491952:MAR181 RS06435
gene id: 491952:MAR181_RS06435
uniprot id: F6CW19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

491952:MAR181 RS10730
gene id: 491952:MAR181_RS10730
uniprot id: F6CTM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

491952:MAR181 RS10160
gene id: 491952:MAR181_RS10160
uniprot id: F6CSH5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

491952:MAR181 RS10040
gene id: 491952:MAR181_RS10040
uniprot id: F6CSF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

491952:MAR181 RS00220
gene id: 491952:MAR181_RS00220
uniprot id: F6CYY5
names: Similarity
messages: Belongs to the DapA family.

491952:MAR181 RS08160
gene id: 491952:MAR181_RS08160
uniprot id: F6CZA9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

491952:MAR181 RS01925
gene id: 491952:MAR181_RS01925
uniprot id: F6CYC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS01505
gene id: 491952:MAR181_RS01505
uniprot id: F6CXQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

491952:MAR181 RS16630
gene id: 491952:MAR181_RS16630
uniprot id: F6CTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS16835
gene id: 491952:MAR181_RS16835
uniprot id: F6CTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS07385
gene id: 491952:MAR181_RS07385
uniprot id: F6CXU3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

491952:MAR181 RS01680
gene id: 491952:MAR181_RS01680
uniprot id: F6CY75
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

491952:MAR181 RS14125
gene id: 491952:MAR181_RS14125
uniprot id: F6CZJ4
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

491952:MAR181 RS09490
gene id: 491952:MAR181_RS09490
uniprot id: F6D189
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

491952:MAR181 RS16255
gene id: 491952:MAR181_RS16255
uniprot id: F6CT60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS13070
gene id: 491952:MAR181_RS13070
uniprot id: F6CXI2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

491952:MAR181 RS09035
gene id: 491952:MAR181_RS09035
uniprot id: F6D0K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

491952:MAR181 RS14460
gene id: 491952:MAR181_RS14460
uniprot id: F6D047
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

491952:MAR181 RS16740
gene id: 491952:MAR181_RS16740
uniprot id: F6CTU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

491952:MAR181 RS13770
gene id: 491952:MAR181_RS13770
uniprot id: F6CYQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

491952:MAR181 RS06500
gene id: 491952:MAR181_RS06500
uniprot id: F6CW32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS01660
gene id: 491952:MAR181_RS01660
uniprot id: F6CY71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS10720
gene id: 491952:MAR181_RS10720
uniprot id: F6CTL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

491952:MAR181 RS07125
gene id: 491952:MAR181_RS07125
uniprot id: F6CXA2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

491952:MAR181 RS02370
gene id: 491952:MAR181_RS02370
uniprot id: F6CZ85
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

491952:MAR181 RS16320
gene id: 491952:MAR181_RS16320
uniprot id: F6CT74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS00080
gene id: 491952:MAR181_RS00080
uniprot id: F6CYV7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

491952:MAR181 RS05485
gene id: 491952:MAR181_RS05485
uniprot id: F6CUL8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

491952:MAR181 RS05980
gene id: 491952:MAR181_RS05980
uniprot id: F6CVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

491952:MAR181 RS12815
gene id: 491952:MAR181_RS12815
uniprot id: F6CWZ0
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

491952:MAR181 RS12435
gene id: 491952:MAR181_RS12435
uniprot id: F6CWB5
names: Similarity
messages: Belongs to the YfgM family.

491952:MAR181 RS06375
gene id: 491952:MAR181_RS06375
uniprot id: F6CW07
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

491952:MAR181 RS08560
gene id: 491952:MAR181_RS08560
uniprot id: F6CZY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS08775
gene id: 491952:MAR181_RS08775
uniprot id: F6D014
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

491952:MAR181 RS11965
gene id: 491952:MAR181_RS11965
uniprot id: F6CVK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS01155
gene id: 491952:MAR181_RS01155
uniprot id: F6CX45
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

491952:MAR181 RS01035
gene id: 491952:MAR181_RS01035
uniprot id: F6CX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS09850
gene id: 491952:MAR181_RS09850
uniprot id: F6CSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS17035
gene id: 491952:MAR181_RS17035
uniprot id: F6CUF4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

491952:MAR181 RS15520
gene id: 491952:MAR181_RS15520
uniprot id: F6CRX2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

491952:MAR181 RS15915
gene id: 491952:MAR181_RS15915
uniprot id: F6CSK0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS14500
gene id: 491952:MAR181_RS14500
uniprot id: F6D054
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

491952:MAR181 RS12985
gene id: 491952:MAR181_RS12985
uniprot id: F6CXG8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

491952:MAR181 RS14235
gene id: 491952:MAR181_RS14235
uniprot id: F6CZL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

491952:MAR181 RS01695
gene id: 491952:MAR181_RS01695
uniprot id: F6CY79
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

491952:MAR181 RS16790
gene id: 491952:MAR181_RS16790
uniprot id: F6CTV6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

491952:MAR181 RS12845
gene id: 491952:MAR181_RS12845
uniprot id: F6CWZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS05335
gene id: 491952:MAR181_RS05335
uniprot id: F6CU45
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

491952:MAR181 RS08480
gene id: 491952:MAR181_RS08480
uniprot id: F6CZW7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

491952:MAR181 RS11505
gene id: 491952:MAR181_RS11505
uniprot id: F6CUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS10690
gene id: 491952:MAR181_RS10690
uniprot id: F6CTL2
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS00555
gene id: 491952:MAR181_RS00555
uniprot id: F6CWC4
names: Similarity
messages: Belongs to the PspA/IM30 family.

491952:MAR181 RS12000
gene id: 491952:MAR181_RS12000
uniprot id: F6CVL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS00510
gene id: 491952:MAR181_RS00510
uniprot id: F6CVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS13195
gene id: 491952:MAR181_RS13195
uniprot id: F6CXK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS02320
gene id: 491952:MAR181_RS02320
uniprot id: F6CZ75
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS07650
gene id: 491952:MAR181_RS07650
uniprot id: F6CXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

491952:MAR181 RS06920
gene id: 491952:MAR181_RS06920
uniprot id: F6CWR5
names: Similarity
messages: Belongs to the aldose epimerase family.

491952:MAR181 RS05490
gene id: 491952:MAR181_RS05490
uniprot id: F6CUL9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

491952:MAR181 RS13760
gene id: 491952:MAR181_RS13760
uniprot id: F6CYQ0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

491952:MAR181 RS06480
gene id: 491952:MAR181_RS06480
uniprot id: F6CW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

491952:MAR181 RS00245
gene id: 491952:MAR181_RS00245
uniprot id: F6CYZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS15410
gene id: 491952:MAR181_RS15410
uniprot id: F6D1G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

491952:MAR181 RS01755
gene id: 491952:MAR181_RS01755
uniprot id: F6CY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

491952:MAR181 RS01785
gene id: 491952:MAR181_RS01785
uniprot id: F6CY98
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

491952:MAR181 RS03560
gene id: 491952:MAR181_RS03560
uniprot id: F6D130
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

491952:MAR181 RS10815
gene id: 491952:MAR181_RS10815
uniprot id: F6CTN7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

491952:MAR181 RS05160
gene id: 491952:MAR181_RS05160
uniprot id: F6CU07
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

491952:MAR181 RS15565
gene id: 491952:MAR181_RS15565
uniprot id: F6CRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

491952:MAR181 RS09620
gene id: 491952:MAR181_RS09620
uniprot id: F6CRR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS01790
gene id: 491952:MAR181_RS01790
uniprot id: F6CY99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

491952:MAR181 RS07165
gene id: 491952:MAR181_RS07165
uniprot id: F6CXB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS01320
gene id: 491952:MAR181_RS01320
uniprot id: F6CXL9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

491952:MAR181 RS14995
gene id: 491952:MAR181_RS14995
uniprot id: F6D0U3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

491952:MAR181 RS04140
gene id: 491952:MAR181_RS04140
uniprot id: F6CS75
names: Subcellular Location Annotation
messages: Cytoplasm

491952:MAR181 RS13400
gene id: 491952:MAR181_RS13400
uniprot id: F6CY28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS05285
gene id: 491952:MAR181_RS05285
uniprot id: F6CU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS12810
gene id: 491952:MAR181_RS12810
uniprot id: F6CWY9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

491952:MAR181 RS09415
gene id: 491952:MAR181_RS09415
uniprot id: F6D174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

491952:MAR181 RS11945
gene id: 491952:MAR181_RS11945
uniprot id: F6CVK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS17465
gene id: 491952:MAR181_RS17465
uniprot id: F6CV33
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

491952:MAR181 RS01645
gene id: 491952:MAR181_RS01645
uniprot id: F6CXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

491952:MAR181 RS10870
gene id: 491952:MAR181_RS10870
uniprot id: F6CTP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

491952:MAR181 RS15405
gene id: 491952:MAR181_RS15405
uniprot id: F6D1G7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

491952:MAR181 RS12580
gene id: 491952:MAR181_RS12580
uniprot id: F6CWU3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

491952:MAR181 RS01100
gene id: 491952:MAR181_RS01100
uniprot id: F6CX35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS03655
gene id: 491952:MAR181_RS03655
uniprot id: F6CRK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

491952:MAR181 RS15025
gene id: 491952:MAR181_RS15025
uniprot id: F6D0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS03895
gene id: 491952:MAR181_RS03895
uniprot id: F6CRQ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

491952:MAR181 RS07555
gene id: 491952:MAR181_RS07555
uniprot id: F6CXW1
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS10710
gene id: 491952:MAR181_RS10710
uniprot id: F6CTL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

491952:MAR181 RS10405
gene id: 491952:MAR181_RS10405
uniprot id: F6CT14
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

491952:MAR181 RS05825
gene id: 491952:MAR181_RS05825
uniprot id: F6CV89
names: Similarity
messages: Belongs to the PhoH family.

491952:MAR181 RS16890
gene id: 491952:MAR181_RS16890
uniprot id: F6CTX6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

491952:MAR181 RS17450
gene id: 491952:MAR181_RS17450
uniprot id: F6CV30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS06000
gene id: 491952:MAR181_RS06000
uniprot id: F6CVC2
names: Similarity
messages: Belongs to the peptidase M18 family.

491952:MAR181 RS13625
gene id: 491952:MAR181_RS13625
uniprot id: F6CYM3
names: Similarity
messages: Belongs to the UPF0319 family.

491952:MAR181 RS12770
gene id: 491952:MAR181_RS12770
uniprot id: F6CWY1
names: Similarity
messages: Belongs to the glutamate synthase family.

491952:MAR181 RS07380
gene id: 491952:MAR181_RS07380
uniprot id: F6CXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

491952:MAR181 RS14255
gene id: 491952:MAR181_RS14255
uniprot id: F6CZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

491952:MAR181 RS15710
gene id: 491952:MAR181_RS15710
uniprot id: F6CS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS00530
gene id: 491952:MAR181_RS00530
uniprot id: F6CVW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS02545
gene id: 491952:MAR181_RS02545
uniprot id: F6CZR5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS15355
gene id: 491952:MAR181_RS15355
uniprot id: F6D1F7
names: Similarity
messages: Belongs to the MQO family.

491952:MAR181 RS10965
gene id: 491952:MAR181_RS10965
uniprot id: F6CTR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

491952:MAR181 RS07800
gene id: 491952:MAR181_RS07800
uniprot id: F6CYG3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

491952:MAR181 RS12370
gene id: 491952:MAR181_RS12370
uniprot id: F6CWA2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

491952:MAR181 RS16035
gene id: 491952:MAR181_RS16035
uniprot id: F6CSM4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS14595
gene id: 491952:MAR181_RS14595
uniprot id: F6D073
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

491952:MAR181 RS04000
gene id: 491952:MAR181_RS04000
uniprot id: F6CS48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

491952:MAR181 RS06185
gene id: 491952:MAR181_RS06185
uniprot id: F6CVF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

491952:MAR181 RS10095
gene id: 491952:MAR181_RS10095
uniprot id: F6CSG2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

491952:MAR181 RS08550
gene id: 491952:MAR181_RS08550
uniprot id: F6CZY1
names: Similarity
messages: Belongs to the GcvT family.

491952:MAR181 RS01650
gene id: 491952:MAR181_RS01650
uniprot id: F6CXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

491952:MAR181 RS02515
gene id: 491952:MAR181_RS02515
uniprot id: F6CZR0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

491952:MAR181 RS09650
gene id: 491952:MAR181_RS09650
uniprot id: F6CRS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03240
gene id: 491952:MAR181_RS03240
uniprot id: F6D0X8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS14220
gene id: 491952:MAR181_RS14220
uniprot id: F6CZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

491952:MAR181 RS08360
gene id: 491952:MAR181_RS08360
uniprot id: F6CZE9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS02460
gene id: 491952:MAR181_RS02460
uniprot id: F6CZP9
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS13425
gene id: 491952:MAR181_RS13425
uniprot id: F6CY33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS02675
gene id: 491952:MAR181_RS02675
uniprot id: F6CZU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

491952:MAR181 RS02100
gene id: 491952:MAR181_RS02100
uniprot id: F6CZ31
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

491952:MAR181 RS15530
gene id: 491952:MAR181_RS15530
uniprot id: F6CRX4
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS05155
gene id: 491952:MAR181_RS05155
uniprot id: F6CU06
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

491952:MAR181 RS01255
gene id: 491952:MAR181_RS01255
uniprot id: F6CX65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS14590
gene id: 491952:MAR181_RS14590
uniprot id: F6D072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS02845
gene id: 491952:MAR181_RS02845
uniprot id: F6D0B0
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS01965
gene id: 491952:MAR181_RS01965
uniprot id: F6CYD4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS16185
gene id: 491952:MAR181_RS16185
uniprot id: F6CSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

491952:MAR181 RS16265
gene id: 491952:MAR181_RS16265
uniprot id: F6CT62
names: Similarity
messages: Belongs to the IlvD/Edd family.

491952:MAR181 RS13735
gene id: 491952:MAR181_RS13735
uniprot id: F6CYP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

491952:MAR181 RS16225
gene id: 491952:MAR181_RS16225
uniprot id: F6CT54
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

491952:MAR181 RS14095
gene id: 491952:MAR181_RS14095
uniprot id: F6CZI8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

491952:MAR181 RS13515
gene id: 491952:MAR181_RS13515
uniprot id: F6CY51
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

491952:MAR181 RS07285
gene id: 491952:MAR181_RS07285
uniprot id: F6CXD3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

491952:MAR181 RS01070
gene id: 491952:MAR181_RS01070
uniprot id: F6CX29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

491952:MAR181 RS12210
gene id: 491952:MAR181_RS12210
uniprot id: F6CW71
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

491952:MAR181 RS12490
gene id: 491952:MAR181_RS12490
uniprot id: F6CWS5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

491952:MAR181 RS17930
gene id: 491952:MAR181_RS17930
uniprot id: F6CVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

491952:MAR181 RS02490
gene id: 491952:MAR181_RS02490
uniprot id: F6CZQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

491952:MAR181 RS00565
gene id: 491952:MAR181_RS00565
uniprot id: F6CWC6
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

491952:MAR181 RS08710
gene id: 491952:MAR181_RS08710
uniprot id: F6D001
names: Similarity
messages: Belongs to the UPF0178 family.

491952:MAR181 RS08195
gene id: 491952:MAR181_RS08195
uniprot id: F6CZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

491952:MAR181 RS10215
gene id: 491952:MAR181_RS10215
uniprot id: F6CSI6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS05700
gene id: 491952:MAR181_RS05700
uniprot id: F6CUR4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

491952:MAR181 RS12755
gene id: 491952:MAR181_RS12755
uniprot id: F6CWX8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

491952:MAR181 RS00835
gene id: 491952:MAR181_RS00835
uniprot id: F6CWH9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS14060
gene id: 491952:MAR181_RS14060
uniprot id: F6CZI1
names: Similarity
messages: Belongs to the pyruvate kinase family.

491952:MAR181 RS08205
gene id: 491952:MAR181_RS08205
uniprot id: F6CZB8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

491952:MAR181 RS17080
gene id: 491952:MAR181_RS17080
uniprot id: F6CUG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

491952:MAR181 RS06950
gene id: 491952:MAR181_RS06950
uniprot id: F6CWS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

491952:MAR181 RS03600
gene id: 491952:MAR181_RS03600
uniprot id: F6CRJ8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

491952:MAR181 RS11685
gene id: 491952:MAR181_RS11685
uniprot id: F6CV01
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS16590
gene id: 491952:MAR181_RS16590
uniprot id: F6CTS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS05600
gene id: 491952:MAR181_RS05600
uniprot id: F6CUP3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

491952:MAR181 RS07290
gene id: 491952:MAR181_RS07290
uniprot id: F6CXD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

491952:MAR181 RS08535
gene id: 491952:MAR181_RS08535
uniprot id: F6CZX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

491952:MAR181 RS16115
gene id: 491952:MAR181_RS16115
uniprot id: F6CSN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

491952:MAR181 RS11060
gene id: 491952:MAR181_RS11060
uniprot id: F6CU82
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

491952:MAR181 RS08475
gene id: 491952:MAR181_RS08475
uniprot id: F6CZW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

491952:MAR181 RS07445
gene id: 491952:MAR181_RS07445
uniprot id: F6CXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

491952:MAR181 RS11070
gene id: 491952:MAR181_RS11070
uniprot id: F6CU84
names: Similarity
messages: Belongs to the isochorismate synthase family.

491952:MAR181 RS16915
gene id: 491952:MAR181_RS16915
uniprot id: F6CTY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

491952:MAR181 RS14730
gene id: 491952:MAR181_RS14730
uniprot id: F6D098
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS12225
gene id: 491952:MAR181_RS12225
uniprot id: F6CW74
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS06195
gene id: 491952:MAR181_RS06195
uniprot id: F6CVX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

491952:MAR181 RS07325
gene id: 491952:MAR181_RS07325
uniprot id: F6CXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

491952:MAR181 RS15450
gene id: 491952:MAR181_RS15450
uniprot id: F6D1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

491952:MAR181 RS11215
gene id: 491952:MAR181_RS11215
uniprot id: F6CUB3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

491952:MAR181 RS05110
gene id: 491952:MAR181_RS05110
uniprot id: F6CTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS16345
gene id: 491952:MAR181_RS16345
uniprot id: F6CT79
names: Similarity
messages: Belongs to the LOG family.

491952:MAR181 RS05315
gene id: 491952:MAR181_RS05315
uniprot id: F6CU40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

491952:MAR181 RS15430
gene id: 491952:MAR181_RS15430
uniprot id: F6D1H2
names: Similarity
messages: Belongs to the UPF0758 family.

491952:MAR181 RS07605
gene id: 491952:MAR181_RS07605
uniprot id: F6CXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS04850
gene id: 491952:MAR181_RS04850
uniprot id: F6CTF0
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS12050
gene id: 491952:MAR181_RS12050
uniprot id: F6CVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

491952:MAR181 RS04880
gene id: 491952:MAR181_RS04880
uniprot id: F6CTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

491952:MAR181 RS01020
gene id: 491952:MAR181_RS01020
uniprot id: F6CX19
names: Similarity
messages: Belongs to the YjdM family.

491952:MAR181 RS05020
gene id: 491952:MAR181_RS05020
uniprot id: F6CTI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

491952:MAR181 RS14210
gene id: 491952:MAR181_RS14210
uniprot id: F6CZL0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

491952:MAR181 RS05680
gene id: 491952:MAR181_RS05680
uniprot id: F6CUR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS01475
gene id: 491952:MAR181_RS01475
uniprot id: F6CXQ1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

491952:MAR181 RS08390
gene id: 491952:MAR181_RS08390
uniprot id: F6CZF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS09560
gene id: 491952:MAR181_RS09560
uniprot id: F6D1A3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

491952:MAR181 RS03735
gene id: 491952:MAR181_RS03735
uniprot id: F6CRM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS09015
gene id: 491952:MAR181_RS09015
uniprot id: F6D0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

491952:MAR181 RS00690
gene id: 491952:MAR181_RS00690
uniprot id: F6CWF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

491952:MAR181 RS15075
gene id: 491952:MAR181_RS15075
uniprot id: F6D0V9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS04945
gene id: 491952:MAR181_RS04945
uniprot id: F6CTG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS13825
gene id: 491952:MAR181_RS13825
uniprot id: F6CYR3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

491952:MAR181 RS04310
gene id: 491952:MAR181_RS04310
uniprot id: F6CSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

491952:MAR181 RS11425
gene id: 491952:MAR181_RS11425
uniprot id: F6CUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

491952:MAR181 RS15035
gene id: 491952:MAR181_RS15035
uniprot id: F6D0V1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

491952:MAR181 RS02275
gene id: 491952:MAR181_RS02275
uniprot id: F6CZ66
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

491952:MAR181 RS09875
gene id: 491952:MAR181_RS09875
uniprot id: F6CSB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

491952:MAR181 RS06425
gene id: 491952:MAR181_RS06425
uniprot id: F6CW17
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

491952:MAR181 RS09420
gene id: 491952:MAR181_RS09420
uniprot id: F6D175
names: Similarity
messages: Belongs to the SAICAR synthetase family.

491952:MAR181 RS13410
gene id: 491952:MAR181_RS13410
uniprot id: F6CY30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

491952:MAR181 RS03135
gene id: 491952:MAR181_RS03135
uniprot id: F6D0F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

491952:MAR181 RS10145
gene id: 491952:MAR181_RS10145
uniprot id: F6CSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

491952:MAR181 RS03590
gene id: 491952:MAR181_RS03590
uniprot id: F6CRJ6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

491952:MAR181 RS15195
gene id: 491952:MAR181_RS15195
uniprot id: F6D1C6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

491952:MAR181 RS01670
gene id: 491952:MAR181_RS01670
uniprot id: F6CY73
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS11145
gene id: 491952:MAR181_RS11145
uniprot id: F6CU99
names: Similarity
messages: Belongs to the TPP enzyme family.

491952:MAR181 RS10735
gene id: 491952:MAR181_RS10735
uniprot id: F6CTM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

491952:MAR181 RS17005
gene id: 491952:MAR181_RS17005
uniprot id: F6CUE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

491952:MAR181 RS14860
gene id: 491952:MAR181_RS14860
uniprot id: F6D0R6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS04145
gene id: 491952:MAR181_RS04145
uniprot id: F6CS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS09940
gene id: 491952:MAR181_RS09940
uniprot id: F6CSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS08790
gene id: 491952:MAR181_RS08790
uniprot id: F6D017
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

491952:MAR181 RS10715
gene id: 491952:MAR181_RS10715
uniprot id: F6CTL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

491952:MAR181 RS02860
gene id: 491952:MAR181_RS02860
uniprot id: F6D0B3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

491952:MAR181 RS09470
gene id: 491952:MAR181_RS09470
uniprot id: F6D185
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

491952:MAR181 RS09855
gene id: 491952:MAR181_RS09855
uniprot id: F6CSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS13480
gene id: 491952:MAR181_RS13480
uniprot id: F6CY44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS09445
gene id: 491952:MAR181_RS09445
uniprot id: F6D180
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS17350
gene id: 491952:MAR181_RS17350
uniprot id: F6CV10
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

491952:MAR181 RS01875
gene id: 491952:MAR181_RS01875
uniprot id: F6CYB6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

491952:MAR181 RS14315
gene id: 491952:MAR181_RS14315
uniprot id: F6CZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

491952:MAR181 RS08450
gene id: 491952:MAR181_RS08450
uniprot id: F6CZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

491952:MAR181 RS17540
gene id: 491952:MAR181_RS17540
uniprot id: F6CV48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS02230
gene id: 491952:MAR181_RS02230
uniprot id: F6CZ57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS08340
gene id: 491952:MAR181_RS08340
uniprot id: F6CZE5
names: Similarity
messages: Belongs to the WrbA family.

491952:MAR181 RS10905
gene id: 491952:MAR181_RS10905
uniprot id: F6CTQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS08985
gene id: 491952:MAR181_RS08985
uniprot id: F6D0J7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

491952:MAR181 RS06680
gene id: 491952:MAR181_RS06680
uniprot id: F6CWL5
names: Similarity
messages: Belongs to the Gfa family.

491952:MAR181 RS06395
gene id: 491952:MAR181_RS06395
uniprot id: F6CW11
names: Similarity
messages: Belongs to the citrate synthase family.

491952:MAR181 RS00430
gene id: 491952:MAR181_RS00430
uniprot id: F6CVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS17375
gene id: 491952:MAR181_RS17375
uniprot id: F6CV15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

491952:MAR181 RS16325
gene id: 491952:MAR181_RS16325
uniprot id: F6CT75
names: Similarity
messages: Belongs to the bacterial secretin family.

491952:MAR181 RS01940
gene id: 491952:MAR181_RS01940
uniprot id: F6CYC9
names: Similarity
messages: Belongs to the ArsC family.

491952:MAR181 RS03385
gene id: 491952:MAR181_RS03385
uniprot id: F6D107
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

491952:MAR181 RS08070
gene id: 491952:MAR181_RS08070
uniprot id: F6CYL9
names: Similarity
messages: Belongs to the CvfB family.

491952:MAR181 RS07240
gene id: 491952:MAR181_RS07240
uniprot id: F6CXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

491952:MAR181 RS02505
gene id: 491952:MAR181_RS02505
uniprot id: F6CZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

491952:MAR181 RS01280
gene id: 491952:MAR181_RS01280
uniprot id: F6CXL1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

491952:MAR181 RS10740
gene id: 491952:MAR181_RS10740
uniprot id: F6CTM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

491952:MAR181 RS03140
gene id: 491952:MAR181_RS03140
uniprot id: F6D0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

491952:MAR181 RS00405
gene id: 491952:MAR181_RS00405
uniprot id: F6CVU1
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS08820
gene id: 491952:MAR181_RS08820
uniprot id: F6D023
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

491952:MAR181 RS13885
gene id: 491952:MAR181_RS13885
uniprot id: F6CYS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

491952:MAR181 RS17095
gene id: 491952:MAR181_RS17095
uniprot id: F6CUG6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

491952:MAR181 RS16805
gene id: 491952:MAR181_RS16805
uniprot id: F6CTV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

491952:MAR181 RS02450
gene id: 491952:MAR181_RS02450
uniprot id: F6CZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

491952:MAR181 RS11320
gene id: 491952:MAR181_RS11320
uniprot id: F6CUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

491952:MAR181 RS10775
gene id: 491952:MAR181_RS10775
uniprot id: F6CTM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

491952:MAR181 RS00085
gene id: 491952:MAR181_RS00085
uniprot id: F6CYV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

491952:MAR181 RS07265
gene id: 491952:MAR181_RS07265
uniprot id: F6CXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

491952:MAR181 RS08175
gene id: 491952:MAR181_RS08175
uniprot id: F6CZB2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS11405
gene id: 491952:MAR181_RS11405
uniprot id: F6CUU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

491952:MAR181 RS16470
gene id: 491952:MAR181_RS16470
uniprot id: F6CTA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS08100
gene id: 491952:MAR181_RS08100
uniprot id: F6CZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

491952:MAR181 RS02040
gene id: 491952:MAR181_RS02040
uniprot id: F6CZ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

491952:MAR181 RS15065
gene id: 491952:MAR181_RS15065
uniprot id: F6D0V7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS08875
gene id: 491952:MAR181_RS08875
uniprot id: F6D0H6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

491952:MAR181 RS03980
gene id: 491952:MAR181_RS03980
uniprot id: F6CS44
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS04055
gene id: 491952:MAR181_RS04055
uniprot id: F6CS59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

491952:MAR181 RS07115
gene id: 491952:MAR181_RS07115
uniprot id: F6CXA0
names: Similarity
messages: Belongs to the pirin family.

491952:MAR181 RS03520
gene id: 491952:MAR181_RS03520
uniprot id: F6D127
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

491952:MAR181 RS09660
gene id: 491952:MAR181_RS09660
uniprot id: F6CRS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

491952:MAR181 RS15570
gene id: 491952:MAR181_RS15570
uniprot id: F6CRY1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

491952:MAR181 RS01825
gene id: 491952:MAR181_RS01825
uniprot id: F6CYA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS03890
gene id: 491952:MAR181_RS03890
uniprot id: F6CRQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS11485
gene id: 491952:MAR181_RS11485
uniprot id: F6CUV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

491952:MAR181 RS16405
gene id: 491952:MAR181_RS16405
uniprot id: F6CT91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS10485
gene id: 491952:MAR181_RS10485
uniprot id: F6CT29
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS02080
gene id: 491952:MAR181_RS02080
uniprot id: F6CZ27
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

491952:MAR181 RS16980
gene id: 491952:MAR181_RS16980
uniprot id: F6CUE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS17840
gene id: 491952:MAR181_RS17840
uniprot id: F6CVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

491952:MAR181 RS06495
gene id: 491952:MAR181_RS06495
uniprot id: F6CW31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

491952:MAR181 RS05060
gene id: 491952:MAR181_RS05060
uniprot id: F6CTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

491952:MAR181 RS12460
gene id: 491952:MAR181_RS12460
uniprot id: F6CWC0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

491952:MAR181 RS10760
gene id: 491952:MAR181_RS10760
uniprot id: F6CTM6
names: Similarity
messages: Belongs to the peptidase S49 family.

491952:MAR181 RS13455
gene id: 491952:MAR181_RS13455
uniprot id: F6CY39
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

491952:MAR181 RS17050
gene id: 491952:MAR181_RS17050
uniprot id: F6CUF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

491952:MAR181 RS17250
gene id: 491952:MAR181_RS17250
uniprot id: F6CUJ1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

491952:MAR181 RS02695
gene id: 491952:MAR181_RS02695
uniprot id: F6CZU4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

491952:MAR181 RS11200
gene id: 491952:MAR181_RS11200
uniprot id: F6CUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

491952:MAR181 RS10600
gene id: 491952:MAR181_RS10600
uniprot id: F6CTJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

491952:MAR181 RS02990
gene id: 491952:MAR181_RS02990
uniprot id: F6D0C9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

491952:MAR181 RS14325
gene id: 491952:MAR181_RS14325
uniprot id: F6CZN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

491952:MAR181 RS12215
gene id: 491952:MAR181_RS12215
uniprot id: F6CW72
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

491952:MAR181 RS09895
gene id: 491952:MAR181_RS09895
uniprot id: F6CSC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

491952:MAR181 RS01515
gene id: 491952:MAR181_RS01515
uniprot id: F6CXQ9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

491952:MAR181 RS03105
gene id: 491952:MAR181_RS03105
uniprot id: F6D0F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS03390
gene id: 491952:MAR181_RS03390
uniprot id: F6D108
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

491952:MAR181 RS04670
gene id: 491952:MAR181_RS04670
uniprot id: F6CSX3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS12445
gene id: 491952:MAR181_RS12445
uniprot id: F6CWB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

491952:MAR181 RS01550
gene id: 491952:MAR181_RS01550
uniprot id: F6CXR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

491952:MAR181 RS04810
gene id: 491952:MAR181_RS04810
uniprot id: F6CTE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

491952:MAR181 RS01800
gene id: 491952:MAR181_RS01800
uniprot id: F6CYA1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

491952:MAR181 RS08055
gene id: 491952:MAR181_RS08055
uniprot id: F6CYL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

491952:MAR181 RS09530
gene id: 491952:MAR181_RS09530
uniprot id: F6D197
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

491952:MAR181 RS03505
gene id: 491952:MAR181_RS03505
uniprot id: F6D124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

491952:MAR181 RS07250
gene id: 491952:MAR181_RS07250
uniprot id: F6CXC6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

491952:MAR181 RS04545
gene id: 491952:MAR181_RS04545
uniprot id: F6CSV0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

491952:MAR181 RS16155
gene id: 491952:MAR181_RS16155
uniprot id: F6CSP8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

491952:MAR181 RS07020
gene id: 491952:MAR181_RS07020
uniprot id: F6CX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS03640
gene id: 491952:MAR181_RS03640
uniprot id: F6CRK6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

491952:MAR181 RS17310
gene id: 491952:MAR181_RS17310
uniprot id: F6CUK2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

491952:MAR181 RS13135
gene id: 491952:MAR181_RS13135
uniprot id: F6CXJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS07925
gene id: 491952:MAR181_RS07925
uniprot id: F6CYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

491952:MAR181 RS06820
gene id: 491952:MAR181_RS06820
uniprot id: F6CWP4
names: Similarity
messages: Belongs to the GST superfamily.

491952:MAR181 RS02075
gene id: 491952:MAR181_RS02075
uniprot id: F6CZ26
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

491952:MAR181 RS08135
gene id: 491952:MAR181_RS08135
uniprot id: F6CZA4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS04975
gene id: 491952:MAR181_RS04975
uniprot id: F6CTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

491952:MAR181 RS09390
gene id: 491952:MAR181_RS09390
uniprot id: F6D169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

491952:MAR181 RS03260
gene id: 491952:MAR181_RS03260
uniprot id: F6D0Y2
names: Similarity
messages: Belongs to the VgrG protein family.

491952:MAR181 RS01795
gene id: 491952:MAR181_RS01795
uniprot id: F6CYA0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

491952:MAR181 RS05345
gene id: 491952:MAR181_RS05345
uniprot id: F6CU47
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS15975
gene id: 491952:MAR181_RS15975
uniprot id: F6CSL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

491952:MAR181 RS04915
gene id: 491952:MAR181_RS04915
uniprot id: F6CTG3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

491952:MAR181 RS01945
gene id: 491952:MAR181_RS01945
uniprot id: F6CYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS16730
gene id: 491952:MAR181_RS16730
uniprot id: F6CTU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

491952:MAR181 RS16960
gene id: 491952:MAR181_RS16960
uniprot id: F6CTZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

491952:MAR181 RS12505
gene id: 491952:MAR181_RS12505
uniprot id: F6CWS8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

491952:MAR181 RS09535
gene id: 491952:MAR181_RS09535
uniprot id: F6D198
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

491952:MAR181 RS08155
gene id: 491952:MAR181_RS08155
uniprot id: F6CZA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

491952:MAR181 RS11015
gene id: 491952:MAR181_RS11015
uniprot id: F6CU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS06180
gene id: 491952:MAR181_RS06180
uniprot id: F6CVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

491952:MAR181 RS18290
gene id: 491952:MAR181_RS18290
uniprot id: F6CVT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

491952:MAR181 RS06850
gene id: 491952:MAR181_RS06850
uniprot id: F6CWQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS11935
gene id: 491952:MAR181_RS11935
uniprot id: F6CVJ9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS03780
gene id: 491952:MAR181_RS03780
uniprot id: F6CRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS16200
gene id: 491952:MAR181_RS16200
uniprot id: F6CSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS13905
gene id: 491952:MAR181_RS13905
uniprot id: F6CYS9
names: Similarity
messages: Belongs to the P(II) protein family.

491952:MAR181 RS02000
gene id: 491952:MAR181_RS02000
uniprot id: F6CYE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

491952:MAR181 RS06430
gene id: 491952:MAR181_RS06430
uniprot id: F6CW18
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

491952:MAR181 RS16550
gene id: 491952:MAR181_RS16550
uniprot id: F6CTB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS04070
gene id: 491952:MAR181_RS04070
uniprot id: F6CS62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS02840
gene id: 491952:MAR181_RS02840
uniprot id: F6D0A9
names: Similarity
messages: Belongs to the GST superfamily.

491952:MAR181 RS10115
gene id: 491952:MAR181_RS10115
uniprot id: F6CSG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

491952:MAR181 RS02710
gene id: 491952:MAR181_RS02710
uniprot id: F6CZU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

491952:MAR181 RS11810
gene id: 491952:MAR181_RS11810
uniprot id: F6CVH5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

491952:MAR181 RS11410
gene id: 491952:MAR181_RS11410
uniprot id: F6CUU4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

491952:MAR181 RS17675
gene id: 491952:MAR181_RS17675
uniprot id: F6CV75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

491952:MAR181 RS09085
gene id: 491952:MAR181_RS09085
uniprot id: F6D0L6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

491952:MAR181 RS13475
gene id: 491952:MAR181_RS13475
uniprot id: F6CY43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

491952:MAR181 RS02810
gene id: 491952:MAR181_RS02810
uniprot id: F6D0A3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS02155
gene id: 491952:MAR181_RS02155
uniprot id: F6CZ42
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

491952:MAR181 RS02270
gene id: 491952:MAR181_RS02270
uniprot id: F6CZ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

491952:MAR181 RS01175
gene id: 491952:MAR181_RS01175
uniprot id: F6CX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS13330
gene id: 491952:MAR181_RS13330
uniprot id: F6CY14
names: Subcellular Location Annotation
messages: Cytoplasm

491952:MAR181 RS09715
gene id: 491952:MAR181_RS09715
uniprot id: F6CRT8
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

491952:MAR181 RS01640
gene id: 491952:MAR181_RS01640
uniprot id: F6CXT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

491952:MAR181 RS13525
gene id: 491952:MAR181_RS13525
uniprot id: F6CY53
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS04430
gene id: 491952:MAR181_RS04430
uniprot id: F6CST0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

491952:MAR181 RS00535
gene id: 491952:MAR181_RS00535
uniprot id: F6CVW7
names: Similarity
messages: Belongs to the Gfa family.

491952:MAR181 RS04395
gene id: 491952:MAR181_RS04395
uniprot id: F6CSS3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

491952:MAR181 RS08725
gene id: 491952:MAR181_RS08725
uniprot id: F6D004
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

491952:MAR181 RS11950
gene id: 491952:MAR181_RS11950
uniprot id: F6CVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS10355
gene id: 491952:MAR181_RS10355
uniprot id: F6CT10
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS05985
gene id: 491952:MAR181_RS05985
uniprot id: F6CVB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

491952:MAR181 RS15540
gene id: 491952:MAR181_RS15540
uniprot id: F6CRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

491952:MAR181 RS00055
gene id: 491952:MAR181_RS00055
uniprot id: F6CYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

491952:MAR181 RS15385
gene id: 491952:MAR181_RS15385
uniprot id: F6D1G3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

491952:MAR181 RS07355
gene id: 491952:MAR181_RS07355
uniprot id: F6CXT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03130
gene id: 491952:MAR181_RS03130
uniprot id: F6D0F7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

491952:MAR181 RS18440
gene id: 491952:MAR181_RS18440
uniprot id: F6CTC1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS08235
gene id: 491952:MAR181_RS08235
uniprot id: F6CZC4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

491952:MAR181 RS14655
gene id: 491952:MAR181_RS14655
uniprot id: F6D083
names: Cofactor
messages: Binds 1 zinc ion per subunit.

491952:MAR181 RS15515
gene id: 491952:MAR181_RS15515
uniprot id: F6CRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS08325
gene id: 491952:MAR181_RS08325
uniprot id: F6CZE2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

491952:MAR181 RS17620
gene id: 491952:MAR181_RS17620
uniprot id: F6CV64
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

491952:MAR181 RS12530
gene id: 491952:MAR181_RS12530
uniprot id: F6CWT3
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS06005
gene id: 491952:MAR181_RS06005
uniprot id: F6CVC3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

491952:MAR181 RS03160
gene id: 491952:MAR181_RS03160
uniprot id: F6D0G3
names: Similarity
messages: Belongs to the UPF0047 family.

491952:MAR181 RS13935
gene id: 491952:MAR181_RS13935
uniprot id: F6CYT6
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

491952:MAR181 RS16460
gene id: 491952:MAR181_RS16460
uniprot id: F6CTA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS10225
gene id: 491952:MAR181_RS10225
uniprot id: F6CSY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

491952:MAR181 RS00320
gene id: 491952:MAR181_RS00320
uniprot id: F6CZ05
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS15665
gene id: 491952:MAR181_RS15665
uniprot id: F6CS01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

491952:MAR181 RS00895
gene id: 491952:MAR181_RS00895
uniprot id: F6CWJ2
names: Similarity
messages: Belongs to the bacterial secretin family.

491952:MAR181 RS02980
gene id: 491952:MAR181_RS02980
uniprot id: F6D0C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

491952:MAR181 RS08925
gene id: 491952:MAR181_RS08925
uniprot id: F6D0I6
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS13780
gene id: 491952:MAR181_RS13780
uniprot id: F6CYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

491952:MAR181 RS11190
gene id: 491952:MAR181_RS11190
uniprot id: F6CUA8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS15595
gene id: 491952:MAR181_RS15595
uniprot id: F6CRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

491952:MAR181 RS16905
gene id: 491952:MAR181_RS16905
uniprot id: F6CTX9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

491952:MAR181 RS09955
gene id: 491952:MAR181_RS09955
uniprot id: F6CSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

491952:MAR181 RS17915
gene id: 491952:MAR181_RS17915
uniprot id: F6CVR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

491952:MAR181 RS03685
gene id: 491952:MAR181_RS03685
uniprot id: F6CRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS02160
gene id: 491952:MAR181_RS02160
uniprot id: F6CZ43
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS08005
gene id: 491952:MAR181_RS08005
uniprot id: F6CYK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS06605
gene id: 491952:MAR181_RS06605
uniprot id: F6CWK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

491952:MAR181 RS09685
gene id: 491952:MAR181_RS09685
uniprot id: F6CRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

491952:MAR181 RS14510
gene id: 491952:MAR181_RS14510
uniprot id: F6D056
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

491952:MAR181 RS06515
gene id: 491952:MAR181_RS06515
uniprot id: F6CW35
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS09355
gene id: 491952:MAR181_RS09355
uniprot id: F6D162
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS13125
gene id: 491952:MAR181_RS13125
uniprot id: F6CXI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

491952:MAR181 RS02790
gene id: 491952:MAR181_RS02790
uniprot id: F6D099
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS02315
gene id: 491952:MAR181_RS02315
uniprot id: F6CZ74
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS13290
gene id: 491952:MAR181_RS13290
uniprot id: F6CY06
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS05265
gene id: 491952:MAR181_RS05265
uniprot id: F6CU30
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

491952:MAR181 RS04320
gene id: 491952:MAR181_RS04320
uniprot id: F6CSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

491952:MAR181 RS09030
gene id: 491952:MAR181_RS09030
uniprot id: F6D0K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

491952:MAR181 RS16925
gene id: 491952:MAR181_RS16925
uniprot id: F6CTY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

491952:MAR181 RS17090
gene id: 491952:MAR181_RS17090
uniprot id: F6CUG5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

491952:MAR181 RS17020
gene id: 491952:MAR181_RS17020
uniprot id: F6CUF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

491952:MAR181 RS03985
gene id: 491952:MAR181_RS03985
uniprot id: F6CS45
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

491952:MAR181 RS16945
gene id: 491952:MAR181_RS16945
uniprot id: F6CTY7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS16420
gene id: 491952:MAR181_RS16420
uniprot id: F6CT94
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS09385
gene id: 491952:MAR181_RS09385
uniprot id: F6D168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

491952:MAR181 RS04930
gene id: 491952:MAR181_RS04930
uniprot id: F6CTG6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

491952:MAR181 RS13430
gene id: 491952:MAR181_RS13430
uniprot id: F6CY34
names: Similarity
messages: Belongs to the ArsC family.

491952:MAR181 RS18005
gene id: 491952:MAR181_RS18005
uniprot id: F6CXS5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS05140
gene id: 491952:MAR181_RS05140
uniprot id: F6CU03
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

491952:MAR181 RS10885
gene id: 491952:MAR181_RS10885
uniprot id: F6CTQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS11470
gene id: 491952:MAR181_RS11470
uniprot id: F6CUV6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

491952:MAR181 RS08675
gene id: 491952:MAR181_RS08675
uniprot id: F6CZZ4
names: Similarity
messages: Belongs to the peptidase S16 family.

491952:MAR181 RS10945
gene id: 491952:MAR181_RS10945
uniprot id: F6CTR3
names: Similarity
messages: Belongs to the Gfa family.

491952:MAR181 RS01340
gene id: 491952:MAR181_RS01340
uniprot id: F6CXM3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

491952:MAR181 RS05150
gene id: 491952:MAR181_RS05150
uniprot id: F6CU05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS06050
gene id: 491952:MAR181_RS06050
uniprot id: F6CVD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS06085
gene id: 491952:MAR181_RS06085
uniprot id: F6CVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

491952:MAR181 RS17935
gene id: 491952:MAR181_RS17935
uniprot id: F6CVS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

491952:MAR181 RS12290
gene id: 491952:MAR181_RS12290
uniprot id: F6CW85
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

491952:MAR181 RS15135
gene id: 491952:MAR181_RS15135
uniprot id: F6D1B4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS05300
gene id: 491952:MAR181_RS05300
uniprot id: F6CU37
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

491952:MAR181 RS17780
gene id: 491952:MAR181_RS17780
uniprot id: F6CVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS11475
gene id: 491952:MAR181_RS11475
uniprot id: F6CUV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

491952:MAR181 RS05655
gene id: 491952:MAR181_RS05655
uniprot id: F6CUQ5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS04350
gene id: 491952:MAR181_RS04350
uniprot id: F6CSR4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

491952:MAR181 RS12055
gene id: 491952:MAR181_RS12055
uniprot id: F6CVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS14310
gene id: 491952:MAR181_RS14310
uniprot id: F6CZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

491952:MAR181 RS02245
gene id: 491952:MAR181_RS02245
uniprot id: F6CZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

491952:MAR181 RS04100
gene id: 491952:MAR181_RS04100
uniprot id: F6CS68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS05890
gene id: 491952:MAR181_RS05890
uniprot id: F6CVA1
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS00670
gene id: 491952:MAR181_RS00670
uniprot id: F6CWE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS11415
gene id: 491952:MAR181_RS11415
uniprot id: F6CUU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

491952:MAR181 RS13980
gene id: 491952:MAR181_RS13980
uniprot id: F6CZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

491952:MAR181 RS13590
gene id: 491952:MAR181_RS13590
uniprot id: F6CY66
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

491952:MAR181 RS05415
gene id: 491952:MAR181_RS05415
uniprot id: F6CU62
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

491952:MAR181 RS11635
gene id: 491952:MAR181_RS11635
uniprot id: F6CUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

491952:MAR181 RS08010
gene id: 491952:MAR181_RS08010
uniprot id: F6CYK7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

491952:MAR181 RS17355
gene id: 491952:MAR181_RS17355
uniprot id: F6CV11
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS14940
gene id: 491952:MAR181_RS14940
uniprot id: F6D0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS04940
gene id: 491952:MAR181_RS04940
uniprot id: F6CTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

491952:MAR181 RS14465
gene id: 491952:MAR181_RS14465
uniprot id: F6D048
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

491952:MAR181 RS11565
gene id: 491952:MAR181_RS11565
uniprot id: F6CUX5
names: Similarity
messages: Belongs to the MipA/OmpV family.

491952:MAR181 RS13945
gene id: 491952:MAR181_RS13945
uniprot id: F6CYT8
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

491952:MAR181 RS09430
gene id: 491952:MAR181_RS09430
uniprot id: F6D177
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

491952:MAR181 RS15560
gene id: 491952:MAR181_RS15560
uniprot id: F6CRX9
names: Similarity
messages: Belongs to the YggT family.

491952:MAR181 RS17370
gene id: 491952:MAR181_RS17370
uniprot id: F6CV14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

491952:MAR181 RS08755
gene id: 491952:MAR181_RS08755
uniprot id: F6D010
names: Similarity
messages: Belongs to the peptidase S49 family.

491952:MAR181 RS14175
gene id: 491952:MAR181_RS14175
uniprot id: F6CZK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

491952:MAR181 RS03800
gene id: 491952:MAR181_RS03800
uniprot id: F6CRN3
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS00370
gene id: 491952:MAR181_RS00370
uniprot id: F6CZ15
names: Similarity
messages: Belongs to the tannase family.

491952:MAR181 RS00855
gene id: 491952:MAR181_RS00855
uniprot id: F6CWI4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

491952:MAR181 RS17925
gene id: 491952:MAR181_RS17925
uniprot id: F6CVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

491952:MAR181 RS13440
gene id: 491952:MAR181_RS13440
uniprot id: F6CY36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

491952:MAR181 RS03755
gene id: 491952:MAR181_RS03755
uniprot id: F6CRM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS04120
gene id: 491952:MAR181_RS04120
uniprot id: F6CS71
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

491952:MAR181 RS17280
gene id: 491952:MAR181_RS17280
uniprot id: F6CUJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

491952:MAR181 RS15090
gene id: 491952:MAR181_RS15090
uniprot id: F6D0W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS06955
gene id: 491952:MAR181_RS06955
uniprot id: F6CWS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS08460
gene id: 491952:MAR181_RS08460
uniprot id: F6CZW3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

491952:MAR181 RS05400
gene id: 491952:MAR181_RS05400
uniprot id: F6CU59
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

491952:MAR181 RS00280
gene id: 491952:MAR181_RS00280
uniprot id: F6CYZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS16985
gene id: 491952:MAR181_RS16985
uniprot id: F6CUE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

491952:MAR181 RS09370
gene id: 491952:MAR181_RS09370
uniprot id: F6D165
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

491952:MAR181 RS09325
gene id: 491952:MAR181_RS09325
uniprot id: F6D156
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS03460
gene id: 491952:MAR181_RS03460
uniprot id: F6D115
names: Subcellular Location Annotation
messages: Cytoplasm

491952:MAR181 RS03025
gene id: 491952:MAR181_RS03025
uniprot id: F6D0D6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

491952:MAR181 RS08435
gene id: 491952:MAR181_RS08435
uniprot id: F6CZG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

491952:MAR181 RS02555
gene id: 491952:MAR181_RS02555
uniprot id: F6CZR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

491952:MAR181 RS03050
gene id: 491952:MAR181_RS03050
uniprot id: F6D0E1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

491952:MAR181 RS01075
gene id: 491952:MAR181_RS01075
uniprot id: F6CX30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

491952:MAR181 RS13385
gene id: 491952:MAR181_RS13385
uniprot id: F6CY25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS16150
gene id: 491952:MAR181_RS16150
uniprot id: F6CSP7
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

491952:MAR181 RS08350
gene id: 491952:MAR181_RS08350
uniprot id: F6CZE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS10850
gene id: 491952:MAR181_RS10850
uniprot id: F6CTP3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

491952:MAR181 RS16895
gene id: 491952:MAR181_RS16895
uniprot id: F6CTX7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS11105
gene id: 491952:MAR181_RS11105
uniprot id: F6CU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

491952:MAR181 RS03565
gene id: 491952:MAR181_RS03565
uniprot id: F6D131
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

491952:MAR181 RS10125
gene id: 491952:MAR181_RS10125
uniprot id: F6CSG8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

491952:MAR181 RS01000
gene id: 491952:MAR181_RS01000
uniprot id: F6CX15
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS05970
gene id: 491952:MAR181_RS05970
uniprot id: F6CVB6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

491952:MAR181 RS16415
gene id: 491952:MAR181_RS16415
uniprot id: F6CT93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

491952:MAR181 RS07765
gene id: 491952:MAR181_RS07765
uniprot id: F6CYF6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

491952:MAR181 RS10925
gene id: 491952:MAR181_RS10925
uniprot id: F6CTQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

491952:MAR181 RS10185
gene id: 491952:MAR181_RS10185
uniprot id: F6CSI0
names: Similarity
messages: Belongs to the YkuD family.

491952:MAR181 RS09545
gene id: 491952:MAR181_RS09545
uniprot id: F6D1A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

491952:MAR181 RS08170
gene id: 491952:MAR181_RS08170
uniprot id: F6CZB1
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS18390
gene id: 491952:MAR181_RS18390
uniprot id: F6CY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

491952:MAR181 RS04335
gene id: 491952:MAR181_RS04335
uniprot id: F6CSR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

491952:MAR181 RS08080
gene id: 491952:MAR181_RS08080
uniprot id: F6CZ93
names: Similarity
messages: Belongs to the UPF0234 family.

491952:MAR181 RS11195
gene id: 491952:MAR181_RS11195
uniprot id: F6CUA9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

491952:MAR181 RS17685
gene id: 491952:MAR181_RS17685
uniprot id: F6CV77
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

491952:MAR181 RS00200
gene id: 491952:MAR181_RS00200
uniprot id: F6CYY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS04235
gene id: 491952:MAR181_RS04235
uniprot id: F6CS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

491952:MAR181 RS12750
gene id: 491952:MAR181_RS12750
uniprot id: F6CWX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

491952:MAR181 RS08240
gene id: 491952:MAR181_RS08240
uniprot id: F6CZC5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

491952:MAR181 RS08485
gene id: 491952:MAR181_RS08485
uniprot id: F6CZW8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

491952:MAR181 RS07960
gene id: 491952:MAR181_RS07960
uniprot id: F6CYJ7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

491952:MAR181 RS08570
gene id: 491952:MAR181_RS08570
uniprot id: F6CZY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS09795
gene id: 491952:MAR181_RS09795
uniprot id: F6CRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS03045
gene id: 491952:MAR181_RS03045
uniprot id: F6D0E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

491952:MAR181 RS15660
gene id: 491952:MAR181_RS15660
uniprot id: F6CS00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

491952:MAR181 RS08705
gene id: 491952:MAR181_RS08705
uniprot id: F6D000
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

491952:MAR181 RS06380
gene id: 491952:MAR181_RS06380
uniprot id: F6CW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

491952:MAR181 RS14355
gene id: 491952:MAR181_RS14355
uniprot id: F6D026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

491952:MAR181 RS05430
gene id: 491952:MAR181_RS05430
uniprot id: F6CU65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS14365
gene id: 491952:MAR181_RS14365
uniprot id: F6D028
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

491952:MAR181 RS09075
gene id: 491952:MAR181_RS09075
uniprot id: F6D0L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

491952:MAR181 RS07220
gene id: 491952:MAR181_RS07220
uniprot id: F6CXC0
names: Similarity
messages: Belongs to the MotB family.

491952:MAR181 RS08540
gene id: 491952:MAR181_RS08540
uniprot id: F6CZX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

491952:MAR181 RS18090
gene id: 491952:MAR181_RS18090
uniprot id: F6CU80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

491952:MAR181 RS14555
gene id: 491952:MAR181_RS14555
uniprot id: F6D065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS08490
gene id: 491952:MAR181_RS08490
uniprot id: F6CZW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

491952:MAR181 RS08030
gene id: 491952:MAR181_RS08030
uniprot id: F6CYL1
names: Similarity
messages: Belongs to the peptidase S24 family.

491952:MAR181 RS03625
gene id: 491952:MAR181_RS03625
uniprot id: F6CRK3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

491952:MAR181 RS09220
gene id: 491952:MAR181_RS09220
uniprot id: F6D133
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

491952:MAR181 RS01040
gene id: 491952:MAR181_RS01040
uniprot id: F6CX23
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS10005
gene id: 491952:MAR181_RS10005
uniprot id: F6CSE4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

491952:MAR181 RS16315
gene id: 491952:MAR181_RS16315
uniprot id: F6CT73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS00100
gene id: 491952:MAR181_RS00100
uniprot id: F6CYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

491952:MAR181 RS00710
gene id: 491952:MAR181_RS00710
uniprot id: F6CWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

491952:MAR181 RS07425
gene id: 491952:MAR181_RS07425
uniprot id: F6CXV1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

491952:MAR181 RS13000
gene id: 491952:MAR181_RS13000
uniprot id: F6CXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS02070
gene id: 491952:MAR181_RS02070
uniprot id: F6CZ25
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS00215
gene id: 491952:MAR181_RS00215
uniprot id: F6CYY4
names: Similarity
messages: Belongs to the proline racemase family.

491952:MAR181 RS03775
gene id: 491952:MAR181_RS03775
uniprot id: F6CRM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS00050
gene id: 491952:MAR181_RS00050
uniprot id: F6CYV1
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS10470
gene id: 491952:MAR181_RS10470
uniprot id: F6CT27
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

491952:MAR181 RS07230
gene id: 491952:MAR181_RS07230
uniprot id: F6CXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

491952:MAR181 RS13185
gene id: 491952:MAR181_RS13185
uniprot id: F6CXK1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

491952:MAR181 RS03930
gene id: 491952:MAR181_RS03930
uniprot id: F6CRQ8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

491952:MAR181 RS00250
gene id: 491952:MAR181_RS00250
uniprot id: F6CYZ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS00910
gene id: 491952:MAR181_RS00910
uniprot id: F6CWJ5
names: Similarity
messages: Belongs to the GSP E family.

491952:MAR181 RS09840
gene id: 491952:MAR181_RS09840
uniprot id: F6CRW3
names: Similarity
messages: Belongs to the IlvD/Edd family.

491952:MAR181 RS07255
gene id: 491952:MAR181_RS07255
uniprot id: F6CXC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

491952:MAR181 RS10605
gene id: 491952:MAR181_RS10605
uniprot id: F6CTJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

491952:MAR181 RS14405
gene id: 491952:MAR181_RS14405
uniprot id: F6D036
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

491952:MAR181 RS04775
gene id: 491952:MAR181_RS04775
uniprot id: F6CTD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

491952:MAR181 RS17315
gene id: 491952:MAR181_RS17315
uniprot id: F6CUK3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

491952:MAR181 RS12365
gene id: 491952:MAR181_RS12365
uniprot id: F6CWA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

491952:MAR181 RS10450
gene id: 491952:MAR181_RS10450
uniprot id: F6CT23
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS00355
gene id: 491952:MAR181_RS00355
uniprot id: F6CZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

491952:MAR181 RS11695
gene id: 491952:MAR181_RS11695
uniprot id: F6CV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

491952:MAR181 RS16190
gene id: 491952:MAR181_RS16190
uniprot id: F6CSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

491952:MAR181 RS13390
gene id: 491952:MAR181_RS13390
uniprot id: F6CY26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

491952:MAR181 RS15180
gene id: 491952:MAR181_RS15180
uniprot id: F6D1C3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS14540
gene id: 491952:MAR181_RS14540
uniprot id: F6D062
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

491952:MAR181 RS03995
gene id: 491952:MAR181_RS03995
uniprot id: F6CS47
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS14875
gene id: 491952:MAR181_RS14875
uniprot id: F6D0R9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

491952:MAR181 RS08335
gene id: 491952:MAR181_RS08335
uniprot id: F6CZE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS07600
gene id: 491952:MAR181_RS07600
uniprot id: F6CXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS12610
gene id: 491952:MAR181_RS12610
uniprot id: F6CWU9
names: Similarity
messages: Belongs to the VgrG protein family.

491952:MAR181 RS14815
gene id: 491952:MAR181_RS14815
uniprot id: F6D0Q7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS12140
gene id: 491952:MAR181_RS12140
uniprot id: F6CW57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS10190
gene id: 491952:MAR181_RS10190
uniprot id: F6CSI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

491952:MAR181 RS08395
gene id: 491952:MAR181_RS08395
uniprot id: F6CZF3
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS15435
gene id: 491952:MAR181_RS15435
uniprot id: F6D1H3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS05640
gene id: 491952:MAR181_RS05640
uniprot id: F6CUQ2
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

491952:MAR181 RS00575
gene id: 491952:MAR181_RS00575
uniprot id: F6CWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS13265
gene id: 491952:MAR181_RS13265
uniprot id: F6CY01
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

491952:MAR181 RS05800
gene id: 491952:MAR181_RS05800
uniprot id: F6CUT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

491952:MAR181 RS17360
gene id: 491952:MAR181_RS17360
uniprot id: F6CV12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

491952:MAR181 RS07315
gene id: 491952:MAR181_RS07315
uniprot id: F6CXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

491952:MAR181 RS02485
gene id: 491952:MAR181_RS02485
uniprot id: F6CZQ4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

491952:MAR181 RS14495
gene id: 491952:MAR181_RS14495
uniprot id: F6D053
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

491952:MAR181 RS04125
gene id: 491952:MAR181_RS04125
uniprot id: F6CS72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

491952:MAR181 RS16280
gene id: 491952:MAR181_RS16280
uniprot id: F6CT65
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS10785
gene id: 491952:MAR181_RS10785
uniprot id: F6CTN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

491952:MAR181 RS00735
gene id: 491952:MAR181_RS00735
uniprot id: F6CWG0
names: Similarity
messages: Belongs to the Gfa family.

491952:MAR181 RS04345
gene id: 491952:MAR181_RS04345
uniprot id: F6CSR3
names: Similarity
messages: Belongs to the UPF0270 family.

491952:MAR181 RS06975
gene id: 491952:MAR181_RS06975
uniprot id: F6CX72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS03070
gene id: 491952:MAR181_RS03070
uniprot id: F6D0E5
names: Similarity
messages: Belongs to the RecJ family.

491952:MAR181 RS12265
gene id: 491952:MAR181_RS12265
uniprot id: F6CW81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

491952:MAR181 RS13275
gene id: 491952:MAR181_RS13275
uniprot id: F6CY03
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

491952:MAR181 RS02180
gene id: 491952:MAR181_RS02180
uniprot id: F6CZ47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS00645
gene id: 491952:MAR181_RS00645
uniprot id: F6CWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

491952:MAR181 RS05795
gene id: 491952:MAR181_RS05795
uniprot id: F6CUT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

491952:MAR181 RS17905
gene id: 491952:MAR181_RS17905
uniprot id: F6CVR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

491952:MAR181 RS16745
gene id: 491952:MAR181_RS16745
uniprot id: F6CTU7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

491952:MAR181 RS11315
gene id: 491952:MAR181_RS11315
uniprot id: F6CUD3
names: Similarity
messages: Belongs to the DinB family.

491952:MAR181 RS13545
gene id: 491952:MAR181_RS13545
uniprot id: F6CY57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

491952:MAR181 RS01835
gene id: 491952:MAR181_RS01835
uniprot id: F6CYA8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

491952:MAR181 RS03250
gene id: 491952:MAR181_RS03250
uniprot id: F6D0Y0
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS02480
gene id: 491952:MAR181_RS02480
uniprot id: F6CZQ3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

491952:MAR181 RS12520
gene id: 491952:MAR181_RS12520
uniprot id: F6CWT1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

491952:MAR181 RS09905
gene id: 491952:MAR181_RS09905
uniprot id: F6CSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

491952:MAR181 RS04635
gene id: 491952:MAR181_RS04635
uniprot id: F6CSW7
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

491952:MAR181 RS14955
gene id: 491952:MAR181_RS14955
uniprot id: F6D0T5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

491952:MAR181 RS05480
gene id: 491952:MAR181_RS05480
uniprot id: F6CUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

491952:MAR181 RS16005
gene id: 491952:MAR181_RS16005
uniprot id: F6CSL8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS10275
gene id: 491952:MAR181_RS10275
uniprot id: F6CSZ4
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

491952:MAR181 RS12495
gene id: 491952:MAR181_RS12495
uniprot id: F6CWS6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

491952:MAR181 RS14050
gene id: 491952:MAR181_RS14050
uniprot id: F6CZH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

491952:MAR181 RS09910
gene id: 491952:MAR181_RS09910
uniprot id: F6CSC5
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

491952:MAR181 RS12060
gene id: 491952:MAR181_RS12060
uniprot id: F6CVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS06225
gene id: 491952:MAR181_RS06225
uniprot id: F6CVX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

491952:MAR181 RS15815
gene id: 491952:MAR181_RS15815
uniprot id: F6CS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS01190
gene id: 491952:MAR181_RS01190
uniprot id: F6CX52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

491952:MAR181 RS17150
gene id: 491952:MAR181_RS17150
uniprot id: F6CUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS05235
gene id: 491952:MAR181_RS05235
uniprot id: F6CU24
names: Similarity
messages: Belongs to the FGGY kinase family.

491952:MAR181 RS15120
gene id: 491952:MAR181_RS15120
uniprot id: F6D1B1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

491952:MAR181 RS14535
gene id: 491952:MAR181_RS14535
uniprot id: F6D061
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

491952:MAR181 RS01870
gene id: 491952:MAR181_RS01870
uniprot id: F6CYB5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

491952:MAR181 RS17415
gene id: 491952:MAR181_RS17415
uniprot id: F6CV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS12325
gene id: 491952:MAR181_RS12325
uniprot id: F6CW93
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

491952:MAR181 RS17175
gene id: 491952:MAR181_RS17175
uniprot id: F6CUH9
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

491952:MAR181 RS11890
gene id: 491952:MAR181_RS11890
uniprot id: F6CVJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

491952:MAR181 RS07830
gene id: 491952:MAR181_RS07830
uniprot id: F6CYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

491952:MAR181 RS09900
gene id: 491952:MAR181_RS09900
uniprot id: F6CSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

491952:MAR181 RS17155
gene id: 491952:MAR181_RS17155
uniprot id: F6CUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS12315
gene id: 491952:MAR181_RS12315
uniprot id: F6CW91
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

491952:MAR181 RS10550
gene id: 491952:MAR181_RS10550
uniprot id: F6CT43
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

491952:MAR181 RS00025
gene id: 491952:MAR181_RS00025
uniprot id: F6CYU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

491952:MAR181 RS11700
gene id: 491952:MAR181_RS11700
uniprot id: F6CV04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS16360
gene id: 491952:MAR181_RS16360
uniprot id: F6CT82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS14725
gene id: 491952:MAR181_RS14725
uniprot id: F6D097
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

491952:MAR181 RS03570
gene id: 491952:MAR181_RS03570
uniprot id: F6CRJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

491952:MAR181 RS08330
gene id: 491952:MAR181_RS08330
uniprot id: F6CZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

491952:MAR181 RS10365
gene id: 491952:MAR181_RS10365
uniprot id: F6CT12
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

491952:MAR181 RS11455
gene id: 491952:MAR181_RS11455
uniprot id: F6CUV3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

491952:MAR181 RS01140
gene id: 491952:MAR181_RS01140
uniprot id: F6CX43
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

491952:MAR181 RS13215
gene id: 491952:MAR181_RS13215
uniprot id: F6CXK7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

491952:MAR181 RS15265
gene id: 491952:MAR181_RS15265
uniprot id: F6D1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS05385
gene id: 491952:MAR181_RS05385
uniprot id: F6CU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS13160
gene id: 491952:MAR181_RS13160
uniprot id: F6CXJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

491952:MAR181 RS05575
gene id: 491952:MAR181_RS05575
uniprot id: F6CUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS03645
gene id: 491952:MAR181_RS03645
uniprot id: F6CRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

491952:MAR181 RS04470
gene id: 491952:MAR181_RS04470
uniprot id: F6CST8
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

491952:MAR181 RS17000
gene id: 491952:MAR181_RS17000
uniprot id: F6CUE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

491952:MAR181 RS15955
gene id: 491952:MAR181_RS15955
uniprot id: F6CSK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

491952:MAR181 RS01120
gene id: 491952:MAR181_RS01120
uniprot id: F6CX39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS15585
gene id: 491952:MAR181_RS15585
uniprot id: F6CRY4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

491952:MAR181 RS08470
gene id: 491952:MAR181_RS08470
uniprot id: F6CZW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

491952:MAR181 RS13795
gene id: 491952:MAR181_RS13795
uniprot id: F6CYQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

491952:MAR181 RS15715
gene id: 491952:MAR181_RS15715
uniprot id: F6CS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS17680
gene id: 491952:MAR181_RS17680
uniprot id: F6CV76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

491952:MAR181 RS04640
gene id: 491952:MAR181_RS04640
uniprot id: F6CSW8
names: Similarity
messages: Belongs to the nitroreductase family.

491952:MAR181 RS16525
gene id: 491952:MAR181_RS16525
uniprot id: F6CTB4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

491952:MAR181 RS17920
gene id: 491952:MAR181_RS17920
uniprot id: F6CVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

491952:MAR181 RS15805
gene id: 491952:MAR181_RS15805
uniprot id: F6CS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

491952:MAR181 RS10165
gene id: 491952:MAR181_RS10165
uniprot id: F6CSH6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

491952:MAR181 RS03810
gene id: 491952:MAR181_RS03810
uniprot id: F6CRN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS07395
gene id: 491952:MAR181_RS07395
uniprot id: F6CXU5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

491952:MAR181 RS09500
gene id: 491952:MAR181_RS09500
uniprot id: F6D191
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

491952:MAR181 RS15165
gene id: 491952:MAR181_RS15165
uniprot id: F6D1C0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS15930
gene id: 491952:MAR181_RS15930
uniprot id: F6CSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

491952:MAR181 RS16965
gene id: 491952:MAR181_RS16965
uniprot id: F6CTZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

491952:MAR181 RS14230
gene id: 491952:MAR181_RS14230
uniprot id: F6CZL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

491952:MAR181 RS00850
gene id: 491952:MAR181_RS00850
uniprot id: F6CWI3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

491952:MAR181 RS04180
gene id: 491952:MAR181_RS04180
uniprot id: F6CS83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

491952:MAR181 RS03785
gene id: 491952:MAR181_RS03785
uniprot id: F6CRN0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

491952:MAR181 RS17505
gene id: 491952:MAR181_RS17505
uniprot id: F6CV41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

491952:MAR181 RS05995
gene id: 491952:MAR181_RS05995
uniprot id: F6CVC1
names: Similarity
messages: Belongs to the peptidase S41A family.

491952:MAR181 RS02495
gene id: 491952:MAR181_RS02495
uniprot id: F6CZQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

491952:MAR181 RS17045
gene id: 491952:MAR181_RS17045
uniprot id: F6CUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

491952:MAR181 RS10660
gene id: 491952:MAR181_RS10660
uniprot id: F6CTK7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

491952:MAR181 RS01265
gene id: 491952:MAR181_RS01265
uniprot id: F6CX67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

491952:MAR181 RS01930
gene id: 491952:MAR181_RS01930
uniprot id: F6CYC7
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS13790
gene id: 491952:MAR181_RS13790
uniprot id: F6CYQ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

491952:MAR181 RS17245
gene id: 491952:MAR181_RS17245
uniprot id: F6CUJ0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

491952:MAR181 RS01560
gene id: 491952:MAR181_RS01560
uniprot id: F6CXR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

491952:MAR181 RS01115
gene id: 491952:MAR181_RS01115
uniprot id: F6CX38
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

491952:MAR181 RS03950
gene id: 491952:MAR181_RS03950
uniprot id: F6CRR2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

491952:MAR181 RS07330
gene id: 491952:MAR181_RS07330
uniprot id: F6CXE1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS03020
gene id: 491952:MAR181_RS03020
uniprot id: F6D0D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

491952:MAR181 RS03580
gene id: 491952:MAR181_RS03580
uniprot id: F6CRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

491952:MAR181 RS11435
gene id: 491952:MAR181_RS11435
uniprot id: F6CUU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

491952:MAR181 RS07450
gene id: 491952:MAR181_RS07450
uniprot id: F6CXV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

491952:MAR181 RS10665
gene id: 491952:MAR181_RS10665
uniprot id: F6CTK8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

491952:MAR181 RS17290
gene id: 491952:MAR181_RS17290
uniprot id: F6CUJ8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

491952:MAR181 RS14000
gene id: 491952:MAR181_RS14000
uniprot id: F6CZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS00180
gene id: 491952:MAR181_RS00180
uniprot id: F6CYX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS16800
gene id: 491952:MAR181_RS16800
uniprot id: F6CTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

491952:MAR181 RS15980
gene id: 491952:MAR181_RS15980
uniprot id: F6CSL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

491952:MAR181 RS02785
gene id: 491952:MAR181_RS02785
uniprot id: F6CZV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

491952:MAR181 RS03030
gene id: 491952:MAR181_RS03030
uniprot id: F6D0D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

491952:MAR181 RS04365
gene id: 491952:MAR181_RS04365
uniprot id: F6CSR7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

491952:MAR181 RS16990
gene id: 491952:MAR181_RS16990
uniprot id: F6CUE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

491952:MAR181 RS02105
gene id: 491952:MAR181_RS02105
uniprot id: F6CZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

491952:MAR181 RS17585
gene id: 491952:MAR181_RS17585
uniprot id: F6CV57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

491952:MAR181 RS10055
gene id: 491952:MAR181_RS10055
uniprot id: F6CSF4
names: Similarity
messages: Belongs to the BolA/IbaG family.

491952:MAR181 RS05965
gene id: 491952:MAR181_RS05965
uniprot id: F6CVB5
names: Similarity
messages: Belongs to the IMPACT family.

491952:MAR181 RS04550
gene id: 491952:MAR181_RS04550
uniprot id: F6CSV1
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS13270
gene id: 491952:MAR181_RS13270
uniprot id: F6CY02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

491952:MAR181 RS17320
gene id: 491952:MAR181_RS17320
uniprot id: F6CUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

491952:MAR181 RS03170
gene id: 491952:MAR181_RS03170
uniprot id: F6D0G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

491952:MAR181 RS13320
gene id: 491952:MAR181_RS13320
uniprot id: F6CY12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

491952:MAR181 RS17195
gene id: 491952:MAR181_RS17195
uniprot id: F6CUI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

491952:MAR181 RS08320
gene id: 491952:MAR181_RS08320
uniprot id: F6CZE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

491952:MAR181 RS16365
gene id: 491952:MAR181_RS16365
uniprot id: F6CT83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

491952:MAR181 RS17610
gene id: 491952:MAR181_RS17610
uniprot id: F6CV62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

491952:MAR181 RS12560
gene id: 491952:MAR181_RS12560
uniprot id: F6CWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

491952:MAR181 RS06245
gene id: 491952:MAR181_RS06245
uniprot id: F6CVY1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

491952:MAR181 RS00075
gene id: 491952:MAR181_RS00075
uniprot id: F6CYV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

491952:MAR181 RS00525
gene id: 491952:MAR181_RS00525
uniprot id: F6CVW5
names: Subcellular Location Annotation
messages: Membrane

491952:MAR181 RS00945
gene id: 491952:MAR181_RS00945
uniprot id: F6CX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

491952:MAR181 RS01375
gene id: 491952:MAR181_RS01375
uniprot id: F6CXN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

491952:MAR181 RS17420
gene id: 491952:MAR181_RS17420
uniprot id: F6CV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS00580
gene id: 491952:MAR181_RS00580
uniprot id: F6CWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

491952:MAR181 RS02445
gene id: 491952:MAR181_RS02445
uniprot id: F6CZP5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

491952:MAR181 RS11995
gene id: 491952:MAR181_RS11995
uniprot id: F6CVL2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

491952:MAR181 RS12965
gene id: 491952:MAR181_RS12965
uniprot id: F6CXG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

491952:MAR181 RS09740
gene id: 491952:MAR181_RS09740
uniprot id: F6CRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.