487521:OCU RS37435
gene id: 487521:OCU_RS37435
uniprot id: H8IL71
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS44670
gene id: 487521:OCU_RS44670
uniprot id: H8IN89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

487521:OCU RS40365
gene id: 487521:OCU_RS40365
uniprot id: H8ISF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

487521:OCU RS43725
gene id: 487521:OCU_RS43725
uniprot id: H8ILG7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

487521:OCU RS36120
gene id: 487521:OCU_RS36120
uniprot id: H8IVT5
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

487521:OCU RS30990
gene id: 487521:OCU_RS30990
uniprot id: H8IWF8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

487521:OCU RS37010
gene id: 487521:OCU_RS37010
uniprot id: H8IK15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS41210
gene id: 487521:OCU_RS41210
uniprot id: H8IUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

487521:OCU RS25350
gene id: 487521:OCU_RS25350
uniprot id: H8IIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

487521:OCU RS47625
gene id: 487521:OCU_RS47625
uniprot id: H8IVA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

487521:OCU RS42515
gene id: 487521:OCU_RS42515
uniprot id: H8II23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

487521:OCU RS46930
gene id: 487521:OCU_RS46930
uniprot id: H8ITH9
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS28855
gene id: 487521:OCU_RS28855
uniprot id: H8IRS6
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS27295
gene id: 487521:OCU_RS27295
uniprot id: H8INA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

487521:OCU RS34485
gene id: 487521:OCU_RS34485
uniprot id: H8IS34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS30805
gene id: 487521:OCU_RS30805
uniprot id: H8IWB7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS30235
gene id: 487521:OCU_RS30235
uniprot id: H8IMX9
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS39915
gene id: 487521:OCU_RS39915
uniprot id: H8IRH4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS49045
gene id: 487521:OCU_RS49045
uniprot id: H8IJC1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

487521:OCU RS39435
gene id: 487521:OCU_RS39435
uniprot id: H8IQJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

487521:OCU RS34110
gene id: 487521:OCU_RS34110
uniprot id: H8IR60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

487521:OCU RS37170
gene id: 487521:OCU_RS37170
uniprot id: H8IK47
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

487521:OCU RS39275
gene id: 487521:OCU_RS39275
uniprot id: H8IQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

487521:OCU RS46275
gene id: 487521:OCU_RS46275
uniprot id: H8ISF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

487521:OCU RS43645
gene id: 487521:OCU_RS43645
uniprot id: H8ILF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS39470
gene id: 487521:OCU_RS39470
uniprot id: H8IQK2
names: Similarity
messages: Belongs to the FPG family.

487521:OCU RS28140
gene id: 487521:OCU_RS28140
uniprot id: H8IQ27
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

487521:OCU RS35910
gene id: 487521:OCU_RS35910
uniprot id: H8IVP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

487521:OCU RS37120
gene id: 487521:OCU_RS37120
uniprot id: H8IK37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46305
gene id: 487521:OCU_RS46305
uniprot id: H8ISG2
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS39945
gene id: 487521:OCU_RS39945
uniprot id: H8IRI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS45820
gene id: 487521:OCU_RS45820
uniprot id: H8IQV1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS28470
gene id: 487521:OCU_RS28470
uniprot id: H8IQW7
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS43940
gene id: 487521:OCU_RS43940
uniprot id: H8IM65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS44675
gene id: 487521:OCU_RS44675
uniprot id: H8IN91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

487521:OCU RS29805
gene id: 487521:OCU_RS29805
uniprot id: H8ITP2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

487521:OCU RS45875
gene id: 487521:OCU_RS45875
uniprot id: H8IQW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

487521:OCU RS33755
gene id: 487521:OCU_RS33755
uniprot id: H8IQ95
names: Similarity
messages: Belongs to the FPG family.

487521:OCU RS36205
gene id: 487521:OCU_RS36205
uniprot id: H8IVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

487521:OCU RS48430
gene id: 487521:OCU_RS48430
uniprot id: B7T027
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS33865
gene id: 487521:OCU_RS33865
uniprot id: H8IQB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

487521:OCU RS48445
gene id: 487521:OCU_RS48445
uniprot id: H8IX63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS32855
gene id: 487521:OCU_RS32855
uniprot id: H8IMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

487521:OCU RS34360
gene id: 487521:OCU_RS34360
uniprot id: H8IS07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS38055
gene id: 487521:OCU_RS38055
uniprot id: H8IM58
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

487521:OCU RS30855
gene id: 487521:OCU_RS30855
uniprot id: H8IWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS32075
gene id: 487521:OCU_RS32075
uniprot id: H8IJU0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS29990
gene id: 487521:OCU_RS29990
uniprot id: H8ITT0
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

487521:OCU RS45890
gene id: 487521:OCU_RS45890
uniprot id: H8IRJ3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS46825
gene id: 487521:OCU_RS46825
uniprot id: H8ITF5
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS27180
gene id: 487521:OCU_RS27180
uniprot id: H8IMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

487521:OCU RS41040
gene id: 487521:OCU_RS41040
uniprot id: H8IU69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

487521:OCU RS44715
gene id: 487521:OCU_RS44715
uniprot id: H8INX9
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

487521:OCU RS47855
gene id: 487521:OCU_RS47855
uniprot id: H8IW44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

487521:OCU RS37300
gene id: 487521:OCU_RS37300
uniprot id: H8IK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS45965
gene id: 487521:OCU_RS45965
uniprot id: H8IRK8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

487521:OCU RS27775
gene id: 487521:OCU_RS27775
uniprot id: H8IP79
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS42650
gene id: 487521:OCU_RS42650
uniprot id: H8II52
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

487521:OCU RS45575
gene id: 487521:OCU_RS45575
uniprot id: H8IQQ1
names: Similarity
messages: Belongs to the group II decarboxylase family.

487521:OCU RS43510
gene id: 487521:OCU_RS43510
uniprot id: H8IKF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

487521:OCU RS46560
gene id: 487521:OCU_RS46560
uniprot id: H8ISK8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS25255
gene id: 487521:OCU_RS25255
uniprot id: H8IHP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS25020
gene id: 487521:OCU_RS25020
uniprot id: H8IHJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

487521:OCU RS39940
gene id: 487521:OCU_RS39940
uniprot id: H8IRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS32180
gene id: 487521:OCU_RS32180
uniprot id: H8IJW1
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS39640
gene id: 487521:OCU_RS39640
uniprot id: H8IRB5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

487521:OCU RS44080
gene id: 487521:OCU_RS44080
uniprot id: H8IM94
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

487521:OCU RS48635
gene id: 487521:OCU_RS48635
uniprot id: H8II83
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46990
gene id: 487521:OCU_RS46990
uniprot id: H8ITJ1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

487521:OCU RS40925
gene id: 487521:OCU_RS40925
uniprot id: H8IU45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS45695
gene id: 487521:OCU_RS45695
uniprot id: H8IQS6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

487521:OCU RS25970
gene id: 487521:OCU_RS25970
uniprot id: H8IJP0
names: Subunit
messages: Homodimer.

487521:OCU RS35915
gene id: 487521:OCU_RS35915
uniprot id: H8IVP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

487521:OCU RS44820
gene id: 487521:OCU_RS44820
uniprot id: H8IP01
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

487521:OCU RS32975
gene id: 487521:OCU_RS32975
uniprot id: H8IMR8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

487521:OCU RS46455
gene id: 487521:OCU_RS46455
uniprot id: H8ISI9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS49090
gene id: 487521:OCU_RS49090
uniprot id: H8IJD0
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS46920
gene id: 487521:OCU_RS46920
uniprot id: H8ITH7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

487521:OCU RS36725
gene id: 487521:OCU_RS36725
uniprot id: H8IIY5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

487521:OCU RS40560
gene id: 487521:OCU_RS40560
uniprot id: H8IT78
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

487521:OCU RS43720
gene id: 487521:OCU_RS43720
uniprot id: H8ILG6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

487521:OCU RS50675
gene id: 487521:OCU_RS50675
uniprot id: H8INY0
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

487521:OCU RS28370
gene id: 487521:OCU_RS28370
uniprot id: H8IQ74
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS37855
gene id: 487521:OCU_RS37855
uniprot id: H8IM15
names: Similarity
messages: Belongs to the glutamine synthetase family.

487521:OCU RS37580
gene id: 487521:OCU_RS37580
uniprot id: H8ILA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

487521:OCU RS36745
gene id: 487521:OCU_RS36745
uniprot id: B7T019
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS30580
gene id: 487521:OCU_RS30580
uniprot id: H8IVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

487521:OCU RS33145
gene id: 487521:OCU_RS33145
uniprot id: H8INJ4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS33910
gene id: 487521:OCU_RS33910
uniprot id: H8IQC7
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS37290
gene id: 487521:OCU_RS37290
uniprot id: B7T043
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS48230
gene id: 487521:OCU_RS48230
uniprot id: H8IX15
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

487521:OCU RS38355
gene id: 487521:OCU_RS38355
uniprot id: H8IMZ4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

487521:OCU RS42950
gene id: 487521:OCU_RS42950
uniprot id: H8IJ68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS33230
gene id: 487521:OCU_RS33230
uniprot id: H8INL1
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS44920
gene id: 487521:OCU_RS44920
uniprot id: H8IP21
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

487521:OCU RS44505
gene id: 487521:OCU_RS44505
uniprot id: H8IN54
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

487521:OCU RS29925
gene id: 487521:OCU_RS29925
uniprot id: H8ITR7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS39650
gene id: 487521:OCU_RS39650
uniprot id: H8IRB7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

487521:OCU RS30965
gene id: 487521:OCU_RS30965
uniprot id: H8IWF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

487521:OCU RS41975
gene id: 487521:OCU_RS41975
uniprot id: H8IWT5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS34860
gene id: 487521:OCU_RS34860
uniprot id: H8IT02
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS27585
gene id: 487521:OCU_RS27585
uniprot id: H8ING0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS38050
gene id: 487521:OCU_RS38050
uniprot id: H8IM57
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

487521:OCU RS42470
gene id: 487521:OCU_RS42470
uniprot id: H8II14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

487521:OCU RS35535
gene id: 487521:OCU_RS35535
uniprot id: H8IUS5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

487521:OCU RS31580
gene id: 487521:OCU_RS31580
uniprot id: H8IIN4
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS29915
gene id: 487521:OCU_RS29915
uniprot id: H8ITR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

487521:OCU RS39120
gene id: 487521:OCU_RS39120
uniprot id: H8IPQ5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

487521:OCU RS26400
gene id: 487521:OCU_RS26400
uniprot id: H8IKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS46165
gene id: 487521:OCU_RS46165
uniprot id: H8IRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

487521:OCU RS27990
gene id: 487521:OCU_RS27990
uniprot id: H8IPC2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS43515
gene id: 487521:OCU_RS43515
uniprot id: H8IKF6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

487521:OCU RS25770
gene id: 487521:OCU_RS25770
uniprot id: H8IJJ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS35475
gene id: 487521:OCU_RS35475
uniprot id: H8IUR3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

487521:OCU RS35180
gene id: 487521:OCU_RS35180
uniprot id: H8ITW1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS45955
gene id: 487521:OCU_RS45955
uniprot id: H8IRK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

487521:OCU RS49935
gene id: 487521:OCU_RS49935
uniprot id: H8ILP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

487521:OCU RS31565
gene id: 487521:OCU_RS31565
uniprot id: H8IIN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS45940
gene id: 487521:OCU_RS45940
uniprot id: H8IRK3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS29440
gene id: 487521:OCU_RS29440
uniprot id: H8ISS4
names: Similarity
messages: Belongs to the AccD/PCCB family.

487521:OCU RS31780
gene id: 487521:OCU_RS31780
uniprot id: H8IIS6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS42290
gene id: 487521:OCU_RS42290
uniprot id: H8IWZ7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

487521:OCU RS48265
gene id: 487521:OCU_RS48265
uniprot id: H8IX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

487521:OCU RS25945
gene id: 487521:OCU_RS25945
uniprot id: P46728
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

487521:OCU RS31945
gene id: 487521:OCU_RS31945
uniprot id: H8IIW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS27500
gene id: 487521:OCU_RS27500
uniprot id: H8INE3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS40200
gene id: 487521:OCU_RS40200
uniprot id: H8ISB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0353 family.
messages: Cell membrane

487521:OCU RS38785
gene id: 487521:OCU_RS38785
uniprot id: H8INW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS37980
gene id: 487521:OCU_RS37980
uniprot id: H8IM40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS32020
gene id: 487521:OCU_RS32020
uniprot id: H8IJS9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS49085
gene id: 487521:OCU_RS49085
uniprot id: H8IJC9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS28710
gene id: 487521:OCU_RS28710
uniprot id: H8IR18
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS49140
gene id: 487521:OCU_RS49140
uniprot id: H8IJE0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

487521:OCU RS27400
gene id: 487521:OCU_RS27400
uniprot id: H8INC2
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS37140
gene id: 487521:OCU_RS37140
uniprot id: H8IK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS33675
gene id: 487521:OCU_RS33675
uniprot id: H8IPJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

487521:OCU RS48090
gene id: 487521:OCU_RS48090
uniprot id: H8IW94
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

487521:OCU RS44235
gene id: 487521:OCU_RS44235
uniprot id: H8IMC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS25720
gene id: 487521:OCU_RS25720
uniprot id: H8IJI8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

487521:OCU RS39290
gene id: 487521:OCU_RS39290
uniprot id: H8IQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

487521:OCU RS28185
gene id: 487521:OCU_RS28185
uniprot id: H8IQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

487521:OCU RS33100
gene id: 487521:OCU_RS33100
uniprot id: H8INI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS37910
gene id: 487521:OCU_RS37910
uniprot id: H8IM26
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

487521:OCU RS28500
gene id: 487521:OCU_RS28500
uniprot id: H8IQX3
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

487521:OCU RS33665
gene id: 487521:OCU_RS33665
uniprot id: H8IPI9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

487521:OCU RS46555
gene id: 487521:OCU_RS46555
uniprot id: H8ISK7
names: Similarity
messages: Belongs to the UPF0234 family.

487521:OCU RS26065
gene id: 487521:OCU_RS26065
uniprot id: H8IJQ9
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

487521:OCU RS46050
gene id: 487521:OCU_RS46050
uniprot id: H8IRM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

487521:OCU RS35865
gene id: 487521:OCU_RS35865
uniprot id: H8IVN1
names: Similarity
messages: Belongs to the glutamine synthetase family.

487521:OCU RS43540
gene id: 487521:OCU_RS43540
uniprot id: H8ILD1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

487521:OCU RS40320
gene id: 487521:OCU_RS40320
uniprot id: H8ISE3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

487521:OCU RS34895
gene id: 487521:OCU_RS34895
uniprot id: H8IT09
names: Similarity
messages: Belongs to the Fur family.

487521:OCU RS46225
gene id: 487521:OCU_RS46225
uniprot id: H8IRR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

487521:OCU RS36250
gene id: 487521:OCU_RS36250
uniprot id: H8IWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

487521:OCU RS29415
gene id: 487521:OCU_RS29415
uniprot id: H8ISR9
names: Similarity
messages: Belongs to the citrate synthase family.

487521:OCU RS32345
gene id: 487521:OCU_RS32345
uniprot id: H8IKW6
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

487521:OCU RS42755
gene id: 487521:OCU_RS42755
uniprot id: H8IJ30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

487521:OCU RS29145
gene id: 487521:OCU_RS29145
uniprot id: H8IRY5
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS35650
gene id: 487521:OCU_RS35650
uniprot id: H8IUU9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS42800
gene id: 487521:OCU_RS42800
uniprot id: H8IJ37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS48125
gene id: 487521:OCU_RS48125
uniprot id: H8IWA1
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS47690
gene id: 487521:OCU_RS47690
uniprot id: H8IVB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS42730
gene id: 487521:OCU_RS42730
uniprot id: H8IJ24
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

487521:OCU RS30700
gene id: 487521:OCU_RS30700
uniprot id: H8IVK2
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS33335
gene id: 487521:OCU_RS33335
uniprot id: H8INN1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS45460
gene id: 487521:OCU_RS45460
uniprot id: H8IQ04
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

487521:OCU RS42995
gene id: 487521:OCU_RS42995
uniprot id: H8IJ77
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

487521:OCU RS40510
gene id: 487521:OCU_RS40510
uniprot id: H8IT68
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS34495
gene id: 487521:OCU_RS34495
uniprot id: H8IS36
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS43200
gene id: 487521:OCU_RS43200
uniprot id: H8IK92
names: Similarity
messages: Belongs to the universal stress protein A family.

487521:OCU RS30840
gene id: 487521:OCU_RS30840
uniprot id: H8IWC5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS44180
gene id: 487521:OCU_RS44180
uniprot id: H8IMB5
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS30770
gene id: 487521:OCU_RS30770
uniprot id: H8IVL7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

487521:OCU RS31450
gene id: 487521:OCU_RS31450
uniprot id: H8IHW4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS44410
gene id: 487521:OCU_RS44410
uniprot id: H8IN35
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

487521:OCU RS34340
gene id: 487521:OCU_RS34340
uniprot id: H8IS03
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS33870
gene id: 487521:OCU_RS33870
uniprot id: H8IQB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

487521:OCU RS33310
gene id: 487521:OCU_RS33310
uniprot id: H8INM6
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS44705
gene id: 487521:OCU_RS44705
uniprot id: H8INX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

487521:OCU RS40610
gene id: 487521:OCU_RS40610
uniprot id: H8IT88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS49495
gene id: 487521:OCU_RS49495
uniprot id: H8IKI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS30095
gene id: 487521:OCU_RS30095
uniprot id: H8IUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

487521:OCU RS38395
gene id: 487521:OCU_RS38395
uniprot id: H8IN02
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS48925
gene id: 487521:OCU_RS48925
uniprot id: H8IIE2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS40940
gene id: 487521:OCU_RS40940
uniprot id: H8IU48
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

487521:OCU RS40960
gene id: 487521:OCU_RS40960
uniprot id: H8IU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

487521:OCU RS43700
gene id: 487521:OCU_RS43700
uniprot id: H8ILG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

487521:OCU RS25380
gene id: 487521:OCU_RS25380
uniprot id: H8IIG1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

487521:OCU RS36845
gene id: 487521:OCU_RS36845
uniprot id: H8IJ09
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS37915
gene id: 487521:OCU_RS37915
uniprot id: H8IM27
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

487521:OCU RS45665
gene id: 487521:OCU_RS45665
uniprot id: H8IQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

487521:OCU RS29570
gene id: 487521:OCU_RS29570
uniprot id: H8ISV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

487521:OCU RS32815
gene id: 487521:OCU_RS32815
uniprot id: H8IMN7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS33960
gene id: 487521:OCU_RS33960
uniprot id: H8IQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS44585
gene id: 487521:OCU_RS44585
uniprot id: H8IN72
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

487521:OCU RS42550
gene id: 487521:OCU_RS42550
uniprot id: H8II30
names: Similarity
messages: Belongs to the P(II) protein family.

487521:OCU RS36535
gene id: 487521:OCU_RS36535
uniprot id: H8IWR2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

487521:OCU RS41080
gene id: 487521:OCU_RS41080
uniprot id: H8IU77
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS31105
gene id: 487521:OCU_RS31105
uniprot id: H8IWI2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS35690
gene id: 487521:OCU_RS35690
uniprot id: H8IUV7
names: Similarity
messages: Belongs to the AccD/PCCB family.

487521:OCU RS47185
gene id: 487521:OCU_RS47185
uniprot id: H8IUC4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS43810
gene id: 487521:OCU_RS43810
uniprot id: H8ILI5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

487521:OCU RS34560
gene id: 487521:OCU_RS34560
uniprot id: H8IS50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS48950
gene id: 487521:OCU_RS48950
uniprot id: H8IIE7
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS33635
gene id: 487521:OCU_RS33635
uniprot id: H8IPI4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

487521:OCU RS27595
gene id: 487521:OCU_RS27595
uniprot id: H8ING2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS45810
gene id: 487521:OCU_RS45810
uniprot id: H8IQU9
names: Similarity
messages: Belongs to the HIBADH-related family.

487521:OCU RS37985
gene id: 487521:OCU_RS37985
uniprot id: H8IM41
names: Similarity
messages: Belongs to the XFP family.

487521:OCU RS26480
gene id: 487521:OCU_RS26480
uniprot id: H8IKW3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

487521:OCU RS47565
gene id: 487521:OCU_RS47565
uniprot id: H8IV89
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS26570
gene id: 487521:OCU_RS26570
uniprot id: H8ILR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS28145
gene id: 487521:OCU_RS28145
uniprot id: H8IQ28
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

487521:OCU RS44945
gene id: 487521:OCU_RS44945
uniprot id: H8IP26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

487521:OCU RS28940
gene id: 487521:OCU_RS28940
uniprot id: H8IRU3
names: Similarity
messages: Belongs to the HIBADH-related family.

487521:OCU RS30205
gene id: 487521:OCU_RS30205
uniprot id: H8IUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

487521:OCU RS34950
gene id: 487521:OCU_RS34950
uniprot id: H8IT19
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

487521:OCU RS49445
gene id: 487521:OCU_RS49445
uniprot id: H8IKH6
names: Subcellular Location Annotation
messages: Cell membrane

487521:OCU RS37395
gene id: 487521:OCU_RS37395
uniprot id: H8IL63
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS44720
gene id: 487521:OCU_RS44720
uniprot id: H8INY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

487521:OCU RS41045
gene id: 487521:OCU_RS41045
uniprot id: H8IU70
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

487521:OCU RS35495
gene id: 487521:OCU_RS35495
uniprot id: H8IUR7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS43855
gene id: 487521:OCU_RS43855
uniprot id: H8ILJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS31525
gene id: 487521:OCU_RS31525
uniprot id: H8IHX9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS45960
gene id: 487521:OCU_RS45960
uniprot id: H8IRK7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

487521:OCU RS45235
gene id: 487521:OCU_RS45235
uniprot id: H8IPV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS39300
gene id: 487521:OCU_RS39300
uniprot id: H8IQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

487521:OCU RS32835
gene id: 487521:OCU_RS32835
uniprot id: H8IMP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: In the C-terminal section; belongs to the ATPase delta chain family.
messages: In the N-terminal section; belongs to the ATPase B chain family.
messages: Membrane
messages: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0).
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

487521:OCU RS47275
gene id: 487521:OCU_RS47275
uniprot id: H8IUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

487521:OCU RS39745
gene id: 487521:OCU_RS39745
uniprot id: H8IRD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS27765
gene id: 487521:OCU_RS27765
uniprot id: H8IP77
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

487521:OCU RS39925
gene id: 487521:OCU_RS39925
uniprot id: H8IRH6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS27490
gene id: 487521:OCU_RS27490
uniprot id: H8INE1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

487521:OCU RS42820
gene id: 487521:OCU_RS42820
uniprot id: H8IJ41
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS46435
gene id: 487521:OCU_RS46435
uniprot id: H8ISI5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

487521:OCU RS41225
gene id: 487521:OCU_RS41225
uniprot id: H8IUZ6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

487521:OCU RS40165
gene id: 487521:OCU_RS40165
uniprot id: H8ISB2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

487521:OCU RS30590
gene id: 487521:OCU_RS30590
uniprot id: H8IVI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

487521:OCU RS26280
gene id: 487521:OCU_RS26280
uniprot id: H8IKS3
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

487521:OCU RS30110
gene id: 487521:OCU_RS30110
uniprot id: H8IUJ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS39755
gene id: 487521:OCU_RS39755
uniprot id: H8IRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS49275
gene id: 487521:OCU_RS49275
uniprot id: H8IJG8
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

487521:OCU RS39660
gene id: 487521:OCU_RS39660
uniprot id: H8IRB9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS38085
gene id: 487521:OCU_RS38085
uniprot id: H8IMT5
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

487521:OCU RS38780
gene id: 487521:OCU_RS38780
uniprot id: H8INW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS35870
gene id: 487521:OCU_RS35870
uniprot id: H8IVN2
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

487521:OCU RS47230
gene id: 487521:OCU_RS47230
uniprot id: H8IUD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

487521:OCU RS25825
gene id: 487521:OCU_RS25825
uniprot id: H8IJK9
names: Similarity
messages: Belongs to the EccE family.

487521:OCU RS42725
gene id: 487521:OCU_RS42725
uniprot id: H8II67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

487521:OCU RS34990
gene id: 487521:OCU_RS34990
uniprot id: H8IT28
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

487521:OCU RS38995
gene id: 487521:OCU_RS38995
uniprot id: H8IPN1
names: Subcellular Location Annotation
messages: Cytoplasm

487521:OCU RS47000
gene id: 487521:OCU_RS47000
uniprot id: H8ITJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

487521:OCU RS25015
gene id: 487521:OCU_RS25015
uniprot id: H8IHJ8
names: Similarity
messages: Belongs to the UPF0232 family.

487521:OCU RS42925
gene id: 487521:OCU_RS42925
uniprot id: H8IJ63
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

487521:OCU RS34590
gene id: 487521:OCU_RS34590
uniprot id: H8IS56
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS42030
gene id: 487521:OCU_RS42030
uniprot id: H8IWU6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS34750
gene id: 487521:OCU_RS34750
uniprot id: H8ISY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS28050
gene id: 487521:OCU_RS28050
uniprot id: H8IQ09
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS32930
gene id: 487521:OCU_RS32930
uniprot id: H8IMQ7
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS42870
gene id: 487521:OCU_RS42870
uniprot id: H8IJ51
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

487521:OCU RS40310
gene id: 487521:OCU_RS40310
uniprot id: H8ISE1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

487521:OCU RS36730
gene id: 487521:OCU_RS36730
uniprot id: H8IIY6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

487521:OCU RS37320
gene id: 487521:OCU_RS37320
uniprot id: H8IL45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS33010
gene id: 487521:OCU_RS33010
uniprot id: H8IMS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

487521:OCU RS34115
gene id: 487521:OCU_RS34115
uniprot id: H8IR61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

487521:OCU RS25695
gene id: 487521:OCU_RS25695
uniprot id: H8IIM9
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS48350
gene id: 487521:OCU_RS48350
uniprot id: H8IX43
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

487521:OCU RS47540
gene id: 487521:OCU_RS47540
uniprot id: H8IV83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

487521:OCU RS45440
gene id: 487521:OCU_RS45440
uniprot id: H8IQ00
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

487521:OCU RS36010
gene id: 487521:OCU_RS36010
uniprot id: H8IVR1
names: Similarity
messages: Belongs to the asparagine synthetase family.

487521:OCU RS27745
gene id: 487521:OCU_RS27745
uniprot id: H8IP72
names: Similarity
messages: Belongs to the fructosamine kinase family.

487521:OCU RS33800
gene id: 487521:OCU_RS33800
uniprot id: H8IQA3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

487521:OCU RS43900
gene id: 487521:OCU_RS43900
uniprot id: H8ILK4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS43870
gene id: 487521:OCU_RS43870
uniprot id: H8ILJ8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

487521:OCU RS40640
gene id: 487521:OCU_RS40640
uniprot id: H8IT94
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS26130
gene id: 487521:OCU_RS26130
uniprot id: H8IKP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS31500
gene id: 487521:OCU_RS31500
uniprot id: H8IHX4
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS40565
gene id: 487521:OCU_RS40565
uniprot id: H8IT79
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

487521:OCU RS47705
gene id: 487521:OCU_RS47705
uniprot id: H8IVB9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS49440
gene id: 487521:OCU_RS49440
uniprot id: H8IKH5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS38955
gene id: 487521:OCU_RS38955
uniprot id: H8IPM0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS42400
gene id: 487521:OCU_RS42400
uniprot id: H8II00
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

487521:OCU RS43500
gene id: 487521:OCU_RS43500
uniprot id: H8IKF3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

487521:OCU RS31000
gene id: 487521:OCU_RS31000
uniprot id: H8IWG0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

487521:OCU RS42450
gene id: 487521:OCU_RS42450
uniprot id: H8II10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

487521:OCU RS44030
gene id: 487521:OCU_RS44030
uniprot id: H8IM84
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS28030
gene id: 487521:OCU_RS28030
uniprot id: H8IPD0
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

487521:OCU RS33235
gene id: 487521:OCU_RS33235
uniprot id: H8INL2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS48580
gene id: 487521:OCU_RS48580
uniprot id: H8II72
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS42395
gene id: 487521:OCU_RS42395
uniprot id: H8IHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

487521:OCU RS30850
gene id: 487521:OCU_RS30850
uniprot id: H8IWC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS30535
gene id: 487521:OCU_RS30535
uniprot id: H8IVG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

487521:OCU RS30785
gene id: 487521:OCU_RS30785
uniprot id: H8IVM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS36200
gene id: 487521:OCU_RS36200
uniprot id: H8IVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

487521:OCU RS41000
gene id: 487521:OCU_RS41000
uniprot id: H8IU61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

487521:OCU RS29240
gene id: 487521:OCU_RS29240
uniprot id: H8ISN3
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS47825
gene id: 487521:OCU_RS47825
uniprot id: H8IW38
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS46805
gene id: 487521:OCU_RS46805
uniprot id: H8ITF1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS39280
gene id: 487521:OCU_RS39280
uniprot id: H8IQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

487521:OCU RS42300
gene id: 487521:OCU_RS42300
uniprot id: H8IWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

487521:OCU RS40170
gene id: 487521:OCU_RS40170
uniprot id: H8ISB3
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS25370
gene id: 487521:OCU_RS25370
uniprot id: H8IIF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

487521:OCU RS32275
gene id: 487521:OCU_RS32275
uniprot id: H8IJY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS44770
gene id: 487521:OCU_RS44770
uniprot id: H8INZ1
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Monovalent cation. The ion could be potassium.

487521:OCU RS41995
gene id: 487521:OCU_RS41995
uniprot id: H8IWT9
names: Similarity
messages: Belongs to the peptidase M16 family.

487521:OCU RS30245
gene id: 487521:OCU_RS30245
uniprot id: H8IUM3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS32795
gene id: 487521:OCU_RS32795
uniprot id: H8IMN3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

487521:OCU RS47665
gene id: 487521:OCU_RS47665
uniprot id: H8IVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

487521:OCU RS26740
gene id: 487521:OCU_RS26740
uniprot id: H8ILV1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

487521:OCU RS39125
gene id: 487521:OCU_RS39125
uniprot id: H8IPQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS34715
gene id: 487521:OCU_RS34715
uniprot id: H8ISX3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

487521:OCU RS41005
gene id: 487521:OCU_RS41005
uniprot id: H8IU62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

487521:OCU RS27445
gene id: 487521:OCU_RS27445
uniprot id: H8IND1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS43775
gene id: 487521:OCU_RS43775
uniprot id: H8ILH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS28055
gene id: 487521:OCU_RS28055
uniprot id: H8IQ10
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS35750
gene id: 487521:OCU_RS35750
uniprot id: H8IUW9
names: Similarity
messages: Belongs to the peptidase S33 family.

487521:OCU RS30080
gene id: 487521:OCU_RS30080
uniprot id: H8IUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

487521:OCU RS34180
gene id: 487521:OCU_RS34180
uniprot id: H8IR75
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS38275
gene id: 487521:OCU_RS38275
uniprot id: H8IMX6
names: Similarity
messages: Belongs to the peptidase S8 family.

487521:OCU RS45215
gene id: 487521:OCU_RS45215
uniprot id: H8IPV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

487521:OCU RS42865
gene id: 487521:OCU_RS42865
uniprot id: H8IJ50
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

487521:OCU RS31275
gene id: 487521:OCU_RS31275
uniprot id: H8IHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS38000
gene id: 487521:OCU_RS38000
uniprot id: H8IM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

487521:OCU RS38880
gene id: 487521:OCU_RS38880
uniprot id: H8IPK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS35270
gene id: 487521:OCU_RS35270
uniprot id: H8ITX9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS47495
gene id: 487521:OCU_RS47495
uniprot id: H8IV74
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS46580
gene id: 487521:OCU_RS46580
uniprot id: H8ISL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

487521:OCU RS33890
gene id: 487521:OCU_RS33890
uniprot id: H8IQC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

487521:OCU RS29780
gene id: 487521:OCU_RS29780
uniprot id: H8ITN7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS41840
gene id: 487521:OCU_RS41840
uniprot id: H8IW16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS26520
gene id: 487521:OCU_RS26520
uniprot id: H8ILQ6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

487521:OCU RS42260
gene id: 487521:OCU_RS42260
uniprot id: H8IWZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

487521:OCU RS39665
gene id: 487521:OCU_RS39665
uniprot id: H8IRC0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

487521:OCU RS43295
gene id: 487521:OCU_RS43295
uniprot id: H8IKB3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

487521:OCU RS45040
gene id: 487521:OCU_RS45040
uniprot id: H8IP46
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS37420
gene id: 487521:OCU_RS37420
uniprot id: H8IL68
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS45245
gene id: 487521:OCU_RS45245
uniprot id: H8IPW0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

487521:OCU RS39625
gene id: 487521:OCU_RS39625
uniprot id: H8IRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

487521:OCU RS36420
gene id: 487521:OCU_RS36420
uniprot id: H8IWN6
names: Similarity
messages: Belongs to the UPF0098 family.

487521:OCU RS49355
gene id: 487521:OCU_RS49355
uniprot id: H8IKF8
names: Similarity
messages: Belongs to the TPP enzyme family.

487521:OCU RS31310
gene id: 487521:OCU_RS31310
uniprot id: H8IHT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS45305
gene id: 487521:OCU_RS45305
uniprot id: H8IPX2
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS41105
gene id: 487521:OCU_RS41105
uniprot id: H8IU82
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS30725
gene id: 487521:OCU_RS30725
uniprot id: H8IVK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

487521:OCU RS46055
gene id: 487521:OCU_RS46055
uniprot id: H8IRM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

487521:OCU RS34705
gene id: 487521:OCU_RS34705
uniprot id: H8ISX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

487521:OCU RS25085
gene id: 487521:OCU_RS25085
uniprot id: H8IHL0
names: Subcellular Location Annotation
messages: Cell membrane

487521:OCU RS39430
gene id: 487521:OCU_RS39430
uniprot id: H8IQJ3
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS49660
gene id: 487521:OCU_RS49660
uniprot id: H8IKM1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

487521:OCU RS46175
gene id: 487521:OCU_RS46175
uniprot id: H8IRQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

487521:OCU RS30800
gene id: 487521:OCU_RS30800
uniprot id: H8IWB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS32820
gene id: 487521:OCU_RS32820
uniprot id: H8IMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

487521:OCU RS40545
gene id: 487521:OCU_RS40545
uniprot id: H8IT75
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS37900
gene id: 487521:OCU_RS37900
uniprot id: H8IM24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS35985
gene id: 487521:OCU_RS35985
uniprot id: H8IVQ6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

487521:OCU RS27970
gene id: 487521:OCU_RS27970
uniprot id: H8IPB8
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS42850
gene id: 487521:OCU_RS42850
uniprot id: H8IJ47
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

487521:OCU RS27510
gene id: 487521:OCU_RS27510
uniprot id: H8INE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS45805
gene id: 487521:OCU_RS45805
uniprot id: H8IQU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS35410
gene id: 487521:OCU_RS35410
uniprot id: H8IU08
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS38935
gene id: 487521:OCU_RS38935
uniprot id: H8IPL6
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

487521:OCU RS30615
gene id: 487521:OCU_RS30615
uniprot id: H8IVI4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

487521:OCU RS44295
gene id: 487521:OCU_RS44295
uniprot id: H8IMD7
names: Similarity
messages: Belongs to the Dps family.

487521:OCU RS28300
gene id: 487521:OCU_RS28300
uniprot id: H8IQ59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

487521:OCU RS29535
gene id: 487521:OCU_RS29535
uniprot id: H8ISU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

487521:OCU RS44865
gene id: 487521:OCU_RS44865
uniprot id: H8IP10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

487521:OCU RS49805
gene id: 487521:OCU_RS49805
uniprot id: H8ILL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS46670
gene id: 487521:OCU_RS46670
uniprot id: H8ISN1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS47020
gene id: 487521:OCU_RS47020
uniprot id: H8ITJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

487521:OCU RS48185
gene id: 487521:OCU_RS48185
uniprot id: H8IWB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

487521:OCU RS46570
gene id: 487521:OCU_RS46570
uniprot id: H8ISL0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS49480
gene id: 487521:OCU_RS49480
uniprot id: H8IKI3
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS35020
gene id: 487521:OCU_RS35020
uniprot id: H8IT35
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS25820
gene id: 487521:OCU_RS25820
uniprot id: H8IJK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

487521:OCU RS25180
gene id: 487521:OCU_RS25180
uniprot id: H8IHM8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

487521:OCU RS43040
gene id: 487521:OCU_RS43040
uniprot id: H8IJ86
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS44935
gene id: 487521:OCU_RS44935
uniprot id: H8IP24
names: Similarity
messages: Belongs to the AccD/PCCB family.

487521:OCU RS47720
gene id: 487521:OCU_RS47720
uniprot id: H8IVC3
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS45580
gene id: 487521:OCU_RS45580
uniprot id: H8IQQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS26505
gene id: 487521:OCU_RS26505
uniprot id: H8ILQ3
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

487521:OCU RS46890
gene id: 487521:OCU_RS46890
uniprot id: H8ITH0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

487521:OCU RS46325
gene id: 487521:OCU_RS46325
uniprot id: H8ISG6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

487521:OCU RS46240
gene id: 487521:OCU_RS46240
uniprot id: H8IRR6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

487521:OCU RS45675
gene id: 487521:OCU_RS45675
uniprot id: H8IQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

487521:OCU RS39735
gene id: 487521:OCU_RS39735
uniprot id: H8IRD4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS45175
gene id: 487521:OCU_RS45175
uniprot id: H8IPU6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

487521:OCU RS45945
gene id: 487521:OCU_RS45945
uniprot id: H8IRK4
names: Similarity
messages: Belongs to the peptidase S49 family.

487521:OCU RS29725
gene id: 487521:OCU_RS29725
uniprot id: H8ITM3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS48120
gene id: 487521:OCU_RS48120
uniprot id: H8IWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

487521:OCU RS37080
gene id: 487521:OCU_RS37080
uniprot id: H8IK29
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS38545
gene id: 487521:OCU_RS38545
uniprot id: H8INR2
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS39240
gene id: 487521:OCU_RS39240
uniprot id: H8IQF4
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

487521:OCU RS33240
gene id: 487521:OCU_RS33240
uniprot id: H8INL3
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS46220
gene id: 487521:OCU_RS46220
uniprot id: H8IRR1
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

487521:OCU RS30655
gene id: 487521:OCU_RS30655
uniprot id: H8IVJ3
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS33835
gene id: 487521:OCU_RS33835
uniprot id: H8IQB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

487521:OCU RS35715
gene id: 487521:OCU_RS35715
uniprot id: H8IUW2
names: Similarity
messages: Belongs to the CdaR family.

487521:OCU RS30020
gene id: 487521:OCU_RS30020
uniprot id: H8IUH8
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

487521:OCU RS36880
gene id: 487521:OCU_RS36880
uniprot id: H8IJ16
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

487521:OCU RS43875
gene id: 487521:OCU_RS43875
uniprot id: H8ILJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS31935
gene id: 487521:OCU_RS31935
uniprot id: H8IIV8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS42665
gene id: 487521:OCU_RS42665
uniprot id: H8II55
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

487521:OCU RS45535
gene id: 487521:OCU_RS45535
uniprot id: H8IQP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

487521:OCU RS45035
gene id: 487521:OCU_RS45035
uniprot id: H8IP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

487521:OCU RS42805
gene id: 487521:OCU_RS42805
uniprot id: H8IJ38
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

487521:OCU RS39005
gene id: 487521:OCU_RS39005
uniprot id: H8IPN3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS36595
gene id: 487521:OCU_RS36595
uniprot id: H8IWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

487521:OCU RS37830
gene id: 487521:OCU_RS37830
uniprot id: H8IM10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS48425
gene id: 487521:OCU_RS48425
uniprot id: H8IX59
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS38600
gene id: 487521:OCU_RS38600
uniprot id: H8INS3
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS36685
gene id: 487521:OCU_RS36685
uniprot id: H8IIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

487521:OCU RS27955
gene id: 487521:OCU_RS27955
uniprot id: H8IPB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS27845
gene id: 487521:OCU_RS27845
uniprot id: H8IP93
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

487521:OCU RS35895
gene id: 487521:OCU_RS35895
uniprot id: H8IVN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

487521:OCU RS43505
gene id: 487521:OCU_RS43505
uniprot id: H8IKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

487521:OCU RS45720
gene id: 487521:OCU_RS45720
uniprot id: H8IQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

487521:OCU RS37050
gene id: 487521:OCU_RS37050
uniprot id: H8IK23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

487521:OCU RS27360
gene id: 487521:OCU_RS27360
uniprot id: H8INB3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

487521:OCU RS45845
gene id: 487521:OCU_RS45845
uniprot id: H8IQV6
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS40405
gene id: 487521:OCU_RS40405
uniprot id: H8IT46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

487521:OCU RS42625
gene id: 487521:OCU_RS42625
uniprot id: H8II47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

487521:OCU RS32580
gene id: 487521:OCU_RS32580
uniprot id: H8IL16
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

487521:OCU RS36750
gene id: 487521:OCU_RS36750
uniprot id: H8IIZ0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

487521:OCU RS42905
gene id: 487521:OCU_RS42905
uniprot id: H8IJ59
names: Similarity
messages: Belongs to the MmpS family.

487521:OCU RS36850
gene id: 487521:OCU_RS36850
uniprot id: H8IJ10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS26555
gene id: 487521:OCU_RS26555
uniprot id: H8ILR3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

487521:OCU RS35920
gene id: 487521:OCU_RS35920
uniprot id: H8IVP3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

487521:OCU RS31010
gene id: 487521:OCU_RS31010
uniprot id: H8IWG2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS25150
gene id: 487521:OCU_RS25150
uniprot id: H8IHM2
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

487521:OCU RS35315
gene id: 487521:OCU_RS35315
uniprot id: H8ITY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
messages: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
messages: Monomer.

487521:OCU RS47260
gene id: 487521:OCU_RS47260
uniprot id: H8IUD9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

487521:OCU RS43525
gene id: 487521:OCU_RS43525
uniprot id: H8ILC7
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

487521:OCU RS42235
gene id: 487521:OCU_RS42235
uniprot id: H8IWY7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

487521:OCU RS27260
gene id: 487521:OCU_RS27260
uniprot id: H8IN93
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

487521:OCU RS45985
gene id: 487521:OCU_RS45985
uniprot id: H8IRL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

487521:OCU RS41540
gene id: 487521:OCU_RS41540
uniprot id: H8IVV5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

487521:OCU RS43895
gene id: 487521:OCU_RS43895
uniprot id: H8ILK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS30065
gene id: 487521:OCU_RS30065
uniprot id: H8IUI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

487521:OCU RS29795
gene id: 487521:OCU_RS29795
uniprot id: H8ITP0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

487521:OCU RS34375
gene id: 487521:OCU_RS34375
uniprot id: H8IS10
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS31515
gene id: 487521:OCU_RS31515
uniprot id: H8IHX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS35470
gene id: 487521:OCU_RS35470
uniprot id: H8IUR2
names: Function
names: Subunit
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.
messages: Monomer.

487521:OCU RS47480
gene id: 487521:OCU_RS47480
uniprot id: H8IV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

487521:OCU RS45405
gene id: 487521:OCU_RS45405
uniprot id: H8IPZ2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

487521:OCU RS41910
gene id: 487521:OCU_RS41910
uniprot id: H8IW30
names: Similarity
messages: Belongs to the AccD/PCCB family.

487521:OCU RS46250
gene id: 487521:OCU_RS46250
uniprot id: H8IRR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

487521:OCU RS28105
gene id: 487521:OCU_RS28105
uniprot id: H8IQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

487521:OCU RS42425
gene id: 487521:OCU_RS42425
uniprot id: H8II05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

487521:OCU RS44765
gene id: 487521:OCU_RS44765
uniprot id: H8INZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS38025
gene id: 487521:OCU_RS38025
uniprot id: H8IM50
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

487521:OCU RS31980
gene id: 487521:OCU_RS31980
uniprot id: H8IJS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS41810
gene id: 487521:OCU_RS41810
uniprot id: H8IW10
names: Similarity
messages: Belongs to the PspA/IM30 family.

487521:OCU RS48015
gene id: 487521:OCU_RS48015
uniprot id: H8IW78
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS34385
gene id: 487521:OCU_RS34385
uniprot id: H8IS13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS40725
gene id: 487521:OCU_RS40725
uniprot id: H8ITB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

487521:OCU RS37760
gene id: 487521:OCU_RS37760
uniprot id: H8ILZ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS40375
gene id: 487521:OCU_RS40375
uniprot id: H8ISF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS37710
gene id: 487521:OCU_RS37710
uniprot id: H8ILY4
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

487521:OCU RS34185
gene id: 487521:OCU_RS34185
uniprot id: H8IR76
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS29695
gene id: 487521:OCU_RS29695
uniprot id: H8ITL7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

487521:OCU RS45925
gene id: 487521:OCU_RS45925
uniprot id: H8IRK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS39310
gene id: 487521:OCU_RS39310
uniprot id: H8IQG8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

487521:OCU RS42115
gene id: 487521:OCU_RS42115
uniprot id: H8IWW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

487521:OCU RS44815
gene id: 487521:OCU_RS44815
uniprot id: H8IP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

487521:OCU RS32915
gene id: 487521:OCU_RS32915
uniprot id: H8IMQ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

487521:OCU RS44360
gene id: 487521:OCU_RS44360
uniprot id: H8IN24
names: Similarity
messages: Belongs to the peptidase S16 family.

487521:OCU RS38340
gene id: 487521:OCU_RS38340
uniprot id: H8IMZ0
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS36660
gene id: 487521:OCU_RS36660
uniprot id: H8IIX2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

487521:OCU RS25075
gene id: 487521:OCU_RS25075
uniprot id: H8IHK8
names: Similarity
messages: Belongs to the UPF0749 family.

487521:OCU RS31015
gene id: 487521:OCU_RS31015
uniprot id: H8IWG3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS34380
gene id: 487521:OCU_RS34380
uniprot id: H8IS11
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS33570
gene id: 487521:OCU_RS33570
uniprot id: H8IPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

487521:OCU RS41765
gene id: 487521:OCU_RS41765
uniprot id: H8IW01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

487521:OCU RS49105
gene id: 487521:OCU_RS49105
uniprot id: H8IJD3
names: Similarity
messages: Belongs to the Dps family.

487521:OCU RS34765
gene id: 487521:OCU_RS34765
uniprot id: H8ISY3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS42565
gene id: 487521:OCU_RS42565
uniprot id: H8II33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

487521:OCU RS36610
gene id: 487521:OCU_RS36610
uniprot id: H8IIW1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

487521:OCU RS39060
gene id: 487521:OCU_RS39060
uniprot id: H8IPP3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

487521:OCU RS42705
gene id: 487521:OCU_RS42705
uniprot id: H8II63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

487521:OCU RS39955
gene id: 487521:OCU_RS39955
uniprot id: H8IRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

487521:OCU RS33785
gene id: 487521:OCU_RS33785
uniprot id: H8IQA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

487521:OCU RS33850
gene id: 487521:OCU_RS33850
uniprot id: H8IQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

487521:OCU RS26500
gene id: 487521:OCU_RS26500
uniprot id: H8ILQ2
names: Similarity
messages: Belongs to the citrate synthase family.

487521:OCU RS46360
gene id: 487521:OCU_RS46360
uniprot id: H8ISH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

487521:OCU RS30600
gene id: 487521:OCU_RS30600
uniprot id: H8IVI2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

487521:OCU RS46005
gene id: 487521:OCU_RS46005
uniprot id: H8IRL6
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

487521:OCU RS33425
gene id: 487521:OCU_RS33425
uniprot id: H8IPE2
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS40855
gene id: 487521:OCU_RS40855
uniprot id: H8IU31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS32175
gene id: 487521:OCU_RS32175
uniprot id: H8IJW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS46070
gene id: 487521:OCU_RS46070
uniprot id: H8IRM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

487521:OCU RS38535
gene id: 487521:OCU_RS38535
uniprot id: H8INR0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS46170
gene id: 487521:OCU_RS46170
uniprot id: H8IRQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

487521:OCU RS44140
gene id: 487521:OCU_RS44140
uniprot id: H8IMA7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

487521:OCU RS47170
gene id: 487521:OCU_RS47170
uniprot id: H8IUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS29660
gene id: 487521:OCU_RS29660
uniprot id: H8ITL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

487521:OCU RS26430
gene id: 487521:OCU_RS26430
uniprot id: H8IKV2
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

487521:OCU RS39540
gene id: 487521:OCU_RS39540
uniprot id: H8IQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

487521:OCU RS26710
gene id: 487521:OCU_RS26710
uniprot id: H8ILU5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

487521:OCU RS38580
gene id: 487521:OCU_RS38580
uniprot id: H8INR9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS26395
gene id: 487521:OCU_RS26395
uniprot id: H8IKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS41725
gene id: 487521:OCU_RS41725
uniprot id: H8IVZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS32680
gene id: 487521:OCU_RS32680
uniprot id: H8IL37
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

487521:OCU RS35925
gene id: 487521:OCU_RS35925
uniprot id: H8IVP4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

487521:OCU RS39185
gene id: 487521:OCU_RS39185
uniprot id: H8IPR8
names: Similarity
messages: Belongs to the UPF0434 family.

487521:OCU RS35160
gene id: 487521:OCU_RS35160
uniprot id: H8ITV7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS45100
gene id: 487521:OCU_RS45100
uniprot id: H8IPT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

487521:OCU RS30945
gene id: 487521:OCU_RS30945
uniprot id: H8IWE9
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS40410
gene id: 487521:OCU_RS40410
uniprot id: H8IT47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

487521:OCU RS27770
gene id: 487521:OCU_RS27770
uniprot id: H8IP78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS42270
gene id: 487521:OCU_RS42270
uniprot id: H8IWZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS33405
gene id: 487521:OCU_RS33405
uniprot id: H8IPD8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS34230
gene id: 487521:OCU_RS34230
uniprot id: H8IR87
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS43770
gene id: 487521:OCU_RS43770
uniprot id: H8ILH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS36255
gene id: 487521:OCU_RS36255
uniprot id: H8IWK4
names: Similarity
messages: Belongs to the YggT family.

487521:OCU RS48200
gene id: 487521:OCU_RS48200
uniprot id: H8IX09
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS39655
gene id: 487521:OCU_RS39655
uniprot id: H8IRB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

487521:OCU RS26165
gene id: 487521:OCU_RS26165
uniprot id: H8IKQ1
names: Similarity
messages: Belongs to the AHA1 family.

487521:OCU RS40785
gene id: 487521:OCU_RS40785
uniprot id: H8IU17
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

487521:OCU RS47500
gene id: 487521:OCU_RS47500
uniprot id: H8IV75
names: Similarity
messages: Belongs to the Nudix hydrolase family.

487521:OCU RS45195
gene id: 487521:OCU_RS45195
uniprot id: H8IPV0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS37540
gene id: 487521:OCU_RS37540
uniprot id: H8IL95
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS32760
gene id: 487521:OCU_RS32760
uniprot id: H8IMM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

487521:OCU RS42485
gene id: 487521:OCU_RS42485
uniprot id: H8II17
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

487521:OCU RS45705
gene id: 487521:OCU_RS45705
uniprot id: H8IQS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

487521:OCU RS45430
gene id: 487521:OCU_RS45430
uniprot id: H8IPZ8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS34815
gene id: 487521:OCU_RS34815
uniprot id: H8ISZ3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS26625
gene id: 487521:OCU_RS26625
uniprot id: H8ILS8
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS41035
gene id: 487521:OCU_RS41035
uniprot id: H8IU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

487521:OCU RS39405
gene id: 487521:OCU_RS39405
uniprot id: H8IQI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

487521:OCU RS42840
gene id: 487521:OCU_RS42840
uniprot id: H8IJ45
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS34850
gene id: 487521:OCU_RS34850
uniprot id: H8IT00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

487521:OCU RS33900
gene id: 487521:OCU_RS33900
uniprot id: H8IQC4
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

487521:OCU RS29205
gene id: 487521:OCU_RS29205
uniprot id: H8IRZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS47805
gene id: 487521:OCU_RS47805
uniprot id: H8IVE1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

487521:OCU RS43290
gene id: 487521:OCU_RS43290
uniprot id: H8IKB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS49710
gene id: 487521:OCU_RS49710
uniprot id: H8IKN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46045
gene id: 487521:OCU_RS46045
uniprot id: H8IRM4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

487521:OCU RS26180
gene id: 487521:OCU_RS26180
uniprot id: H8IKQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

487521:OCU RS44320
gene id: 487521:OCU_RS44320
uniprot id: H8IN15
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

487521:OCU RS46000
gene id: 487521:OCU_RS46000
uniprot id: H8IRL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

487521:OCU RS35960
gene id: 487521:OCU_RS35960
uniprot id: H8IVQ1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS46630
gene id: 487521:OCU_RS46630
uniprot id: H8ISM2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

487521:OCU RS48725
gene id: 487521:OCU_RS48725
uniprot id: H8IIA2
names: Similarity
messages: Belongs to the peptidase M13 family.

487521:OCU RS39160
gene id: 487521:OCU_RS39160
uniprot id: H8IPR3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

487521:OCU RS29260
gene id: 487521:OCU_RS29260
uniprot id: H8ISN7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS30240
gene id: 487521:OCU_RS30240
uniprot id: H8IMY0
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS32570
gene id: 487521:OCU_RS32570
uniprot id: H8IL14
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

487521:OCU RS35900
gene id: 487521:OCU_RS35900
uniprot id: H8IVN9
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS27080
gene id: 487521:OCU_RS27080
uniprot id: H8IMI2
names: Similarity
messages: Belongs to the GSP E family.

487521:OCU RS31540
gene id: 487521:OCU_RS31540
uniprot id: H8IHY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS48320
gene id: 487521:OCU_RS48320
uniprot id: H8IX36
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

487521:OCU RS34670
gene id: 487521:OCU_RS34670
uniprot id: H8ISW2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

487521:OCU RS42920
gene id: 487521:OCU_RS42920
uniprot id: H8IJ62
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

487521:OCU RS34170
gene id: 487521:OCU_RS34170
uniprot id: H8IR73
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS47090
gene id: 487521:OCU_RS47090
uniprot id: H8IUA5
names: Cofactor
messages: Can also use Mn(2+) ion.

487521:OCU RS46460
gene id: 487521:OCU_RS46460
uniprot id: H8ISJ0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS28835
gene id: 487521:OCU_RS28835
uniprot id: H8IRS2
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS41650
gene id: 487521:OCU_RS41650
uniprot id: H8IVX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS41505
gene id: 487521:OCU_RS41505
uniprot id: H8IV55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS43205
gene id: 487521:OCU_RS43205
uniprot id: H8IK93
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS29135
gene id: 487521:OCU_RS29135
uniprot id: H8IRY3
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS27050
gene id: 487521:OCU_RS27050
uniprot id: H8IMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

487521:OCU RS41525
gene id: 487521:OCU_RS41525
uniprot id: H8IV59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

487521:OCU RS27755
gene id: 487521:OCU_RS27755
uniprot id: H8IP74
names: Similarity
messages: Belongs to the TPP enzyme family.

487521:OCU RS45930
gene id: 487521:OCU_RS45930
uniprot id: H8IRK1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS29905
gene id: 487521:OCU_RS29905
uniprot id: H8ITR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

487521:OCU RS27505
gene id: 487521:OCU_RS27505
uniprot id: H8INE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46100
gene id: 487521:OCU_RS46100
uniprot id: H8IRN5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

487521:OCU RS44955
gene id: 487521:OCU_RS44955
uniprot id: H8IP28
names: Similarity
messages: Belongs to the SufE family.

487521:OCU RS30760
gene id: 487521:OCU_RS30760
uniprot id: H8IVL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS33245
gene id: 487521:OCU_RS33245
uniprot id: H8INL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS39295
gene id: 487521:OCU_RS39295
uniprot id: H8IQG5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

487521:OCU RS47735
gene id: 487521:OCU_RS47735
uniprot id: H8IVC6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

487521:OCU RS42025
gene id: 487521:OCU_RS42025
uniprot id: H8IWU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS29025
gene id: 487521:OCU_RS29025
uniprot id: H8IRW0
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS34020
gene id: 487521:OCU_RS34020
uniprot id: H8IQF0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS44645
gene id: 487521:OCU_RS44645
uniprot id: H8IN84
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

487521:OCU RS39105
gene id: 487521:OCU_RS39105
uniprot id: H8IPQ2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS30135
gene id: 487521:OCU_RS30135
uniprot id: H8IUK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS32955
gene id: 487521:OCU_RS32955
uniprot id: H8IMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

487521:OCU RS40755
gene id: 487521:OCU_RS40755
uniprot id: H8ITB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

487521:OCU RS46675
gene id: 487521:OCU_RS46675
uniprot id: H8ITC3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS34265
gene id: 487521:OCU_RS34265
uniprot id: H8IR95
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS42590
gene id: 487521:OCU_RS42590
uniprot id: H8II38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

487521:OCU RS28775
gene id: 487521:OCU_RS28775
uniprot id: H8IR31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS32675
gene id: 487521:OCU_RS32675
uniprot id: H8IL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

487521:OCU RS42130
gene id: 487521:OCU_RS42130
uniprot id: H8IWW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS38435
gene id: 487521:OCU_RS38435
uniprot id: H8IN10
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS42225
gene id: 487521:OCU_RS42225
uniprot id: H8IWY5
names: Similarity
messages: Belongs to the glutamine synthetase family.

487521:OCU RS25635
gene id: 487521:OCU_RS25635
uniprot id: H8IIL7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS33940
gene id: 487521:OCU_RS33940
uniprot id: H8IQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

487521:OCU RS42085
gene id: 487521:OCU_RS42085
uniprot id: H8IWV7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS35780
gene id: 487521:OCU_RS35780
uniprot id: H8IUX5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS42970
gene id: 487521:OCU_RS42970
uniprot id: H8IJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

487521:OCU RS40750
gene id: 487521:OCU_RS40750
uniprot id: H8ITB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

487521:OCU RS37370
gene id: 487521:OCU_RS37370
uniprot id: H8IL57
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS30995
gene id: 487521:OCU_RS30995
uniprot id: H8IWF9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS42860
gene id: 487521:OCU_RS42860
uniprot id: H8IJ49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS34925
gene id: 487521:OCU_RS34925
uniprot id: H8IT15
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

487521:OCU RS27485
gene id: 487521:OCU_RS27485
uniprot id: H8INE0
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

487521:OCU RS34010
gene id: 487521:OCU_RS34010
uniprot id: H8IQE8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS26805
gene id: 487521:OCU_RS26805
uniprot id: H8ILW4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

487521:OCU RS45360
gene id: 487521:OCU_RS45360
uniprot id: H8IPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

487521:OCU RS44825
gene id: 487521:OCU_RS44825
uniprot id: H8IP02
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS39580
gene id: 487521:OCU_RS39580
uniprot id: H8IQM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

487521:OCU RS48110
gene id: 487521:OCU_RS48110
uniprot id: H8IW98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

487521:OCU RS50705
gene id: 487521:OCU_RS50705
uniprot id: H8IQT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

487521:OCU RS40975
gene id: 487521:OCU_RS40975
uniprot id: H8IU56
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
messages: Binds 1 phosphopantetheine covalently.
messages: Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.

487521:OCU RS42110
gene id: 487521:OCU_RS42110
uniprot id: H8IWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

487521:OCU RS30660
gene id: 487521:OCU_RS30660
uniprot id: H8IVJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS26680
gene id: 487521:OCU_RS26680
uniprot id: H8ILT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

487521:OCU RS38290
gene id: 487521:OCU_RS38290
uniprot id: H8IMX9
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS38250
gene id: 487521:OCU_RS38250
uniprot id: H8IMW9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS43390
gene id: 487521:OCU_RS43390
uniprot id: H8IKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS42460
gene id: 487521:OCU_RS42460
uniprot id: H8II12
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

487521:OCU RS37400
gene id: 487521:OCU_RS37400
uniprot id: H8IL64
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS34215
gene id: 487521:OCU_RS34215
uniprot id: H8IR83
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

487521:OCU RS47605
gene id: 487521:OCU_RS47605
uniprot id: H8IV99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

487521:OCU RS30130
gene id: 487521:OCU_RS30130
uniprot id: H8IUK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

487521:OCU RS48360
gene id: 487521:OCU_RS48360
uniprot id: H8IX45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS40115
gene id: 487521:OCU_RS40115
uniprot id: H8ISA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

487521:OCU RS46440
gene id: 487521:OCU_RS46440
uniprot id: H8ISI6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

487521:OCU RS28580
gene id: 487521:OCU_RS28580
uniprot id: H8IQZ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

487521:OCU RS45710
gene id: 487521:OCU_RS45710
uniprot id: H8IQS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

487521:OCU RS42385
gene id: 487521:OCU_RS42385
uniprot id: H8IHZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

487521:OCU RS35235
gene id: 487521:OCU_RS35235
uniprot id: H8ITX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

487521:OCU RS43255
gene id: 487521:OCU_RS43255
uniprot id: H8IKA4
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS30575
gene id: 487521:OCU_RS30575
uniprot id: H8IVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

487521:OCU RS38760
gene id: 487521:OCU_RS38760
uniprot id: H8INV6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

487521:OCU RS32015
gene id: 487521:OCU_RS32015
uniprot id: H8IJS8
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

487521:OCU RS37060
gene id: 487521:OCU_RS37060
uniprot id: H8IK25
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

487521:OCU RS32365
gene id: 487521:OCU_RS32365
uniprot id: H8IKX1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

487521:OCU RS46210
gene id: 487521:OCU_RS46210
uniprot id: H8IRQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS26445
gene id: 487521:OCU_RS26445
uniprot id: H8IKV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

487521:OCU RS33210
gene id: 487521:OCU_RS33210
uniprot id: H8INK7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS40850
gene id: 487521:OCU_RS40850
uniprot id: H8IU30
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS40660
gene id: 487521:OCU_RS40660
uniprot id: H8IT98
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

487521:OCU RS43820
gene id: 487521:OCU_RS43820
uniprot id: H8ILI7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS31460
gene id: 487521:OCU_RS31460
uniprot id: H8IHW6
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS46405
gene id: 487521:OCU_RS46405
uniprot id: H8ISH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS40500
gene id: 487521:OCU_RS40500
uniprot id: H8IT66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

487521:OCU RS41185
gene id: 487521:OCU_RS41185
uniprot id: H8IUY8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

487521:OCU RS34785
gene id: 487521:OCU_RS34785
uniprot id: H8ISY7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS47450
gene id: 487521:OCU_RS47450
uniprot id: H8IV64
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

487521:OCU RS44060
gene id: 487521:OCU_RS44060
uniprot id: H8IM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

487521:OCU RS32410
gene id: 487521:OCU_RS32410
uniprot id: H8IKY0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS47385
gene id: 487521:OCU_RS47385
uniprot id: H8IUG4
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

487521:OCU RS26265
gene id: 487521:OCU_RS26265
uniprot id: H8IKS0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS36115
gene id: 487521:OCU_RS36115
uniprot id: H8IVT4
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

487521:OCU RS38455
gene id: 487521:OCU_RS38455
uniprot id: H8INP4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS41410
gene id: 487521:OCU_RS41410
uniprot id: H8IV36
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS36525
gene id: 487521:OCU_RS36525
uniprot id: H8IWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

487521:OCU RS44900
gene id: 487521:OCU_RS44900
uniprot id: H8IP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

487521:OCU RS33420
gene id: 487521:OCU_RS33420
uniprot id: H8IPE1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

487521:OCU RS31840
gene id: 487521:OCU_RS31840
uniprot id: H8IIT7
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS45290
gene id: 487521:OCU_RS45290
uniprot id: H8IPW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

487521:OCU RS42570
gene id: 487521:OCU_RS42570
uniprot id: H8II34
names: Similarity
messages: Belongs to the acylphosphatase family.

487521:OCU RS47775
gene id: 487521:OCU_RS47775
uniprot id: H8IVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

487521:OCU RS34510
gene id: 487521:OCU_RS34510
uniprot id: H8IS39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS29590
gene id: 487521:OCU_RS29590
uniprot id: H8ISV4
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS42205
gene id: 487521:OCU_RS42205
uniprot id: H8IWY1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS38170
gene id: 487521:OCU_RS38170
uniprot id: H8IMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

487521:OCU RS44455
gene id: 487521:OCU_RS44455
uniprot id: H8IN44
names: Similarity
messages: Belongs to the MmpS family.

487521:OCU RS41480
gene id: 487521:OCU_RS41480
uniprot id: H8IV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

487521:OCU RS49895
gene id: 487521:OCU_RS49895
uniprot id: H8ILN6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

487521:OCU RS27195
gene id: 487521:OCU_RS27195
uniprot id: H8IMK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

487521:OCU RS41025
gene id: 487521:OCU_RS41025
uniprot id: H8IU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

487521:OCU RS30010
gene id: 487521:OCU_RS30010
uniprot id: H8IUH6
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS32800
gene id: 487521:OCU_RS32800
uniprot id: H8IMN4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

487521:OCU RS27575
gene id: 487521:OCU_RS27575
uniprot id: H8INF8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS25685
gene id: 487521:OCU_RS25685
uniprot id: H8IIM7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS38180
gene id: 487521:OCU_RS38180
uniprot id: H8IMV5
names: Similarity
messages: Belongs to the TPP enzyme family.

487521:OCU RS41235
gene id: 487521:OCU_RS41235
uniprot id: H8IUZ9
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

487521:OCU RS31760
gene id: 487521:OCU_RS31760
uniprot id: H8IIS2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS34790
gene id: 487521:OCU_RS34790
uniprot id: H8ISY8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS45450
gene id: 487521:OCU_RS45450
uniprot id: H8IQ02
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

487521:OCU RS32150
gene id: 487521:OCU_RS32150
uniprot id: H8IJV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS46500
gene id: 487521:OCU_RS46500
uniprot id: H8ISJ8
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS48750
gene id: 487521:OCU_RS48750
uniprot id: H8IIA7
names: Similarity
messages: Belongs to the CsoR family.

487521:OCU RS29490
gene id: 487521:OCU_RS29490
uniprot id: H8IST4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

487521:OCU RS41760
gene id: 487521:OCU_RS41760
uniprot id: H8IW00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

487521:OCU RS26780
gene id: 487521:OCU_RS26780
uniprot id: H8ILV9
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

487521:OCU RS27410
gene id: 487521:OCU_RS27410
uniprot id: H8INC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

487521:OCU RS47080
gene id: 487521:OCU_RS47080
uniprot id: H8IUA2
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS28985
gene id: 487521:OCU_RS28985
uniprot id: H8IRV2
names: Similarity
messages: Belongs to the LuxC family.

487521:OCU RS34480
gene id: 487521:OCU_RS34480
uniprot id: H8IS33
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS33610
gene id: 487521:OCU_RS33610
uniprot id: H8IPH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS30455
gene id: 487521:OCU_RS30455
uniprot id: H8IVF2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

487521:OCU RS46335
gene id: 487521:OCU_RS46335
uniprot id: H8ISG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

487521:OCU RS43175
gene id: 487521:OCU_RS43175
uniprot id: H8IK87
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS42380
gene id: 487521:OCU_RS42380
uniprot id: H8IHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

487521:OCU RS31045
gene id: 487521:OCU_RS31045
uniprot id: H8IWG9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS29930
gene id: 487521:OCU_RS29930
uniprot id: H8ITR8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

487521:OCU RS41260
gene id: 487521:OCU_RS41260
uniprot id: H8IV04
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS39265
gene id: 487521:OCU_RS39265
uniprot id: H8IQF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

487521:OCU RS27655
gene id: 487521:OCU_RS27655
uniprot id: H8IP54
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

487521:OCU RS37810
gene id: 487521:OCU_RS37810
uniprot id: Q49575
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mycobacterial A85 antigen family.
messages: Secreted
messages: The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).

487521:OCU RS28340
gene id: 487521:OCU_RS28340
uniprot id: H8IQ68
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

487521:OCU RS43745
gene id: 487521:OCU_RS43745
uniprot id: H8ILH2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

487521:OCU RS39415
gene id: 487521:OCU_RS39415
uniprot id: H8IQI9
names: Similarity
messages: Belongs to the universal stress protein A family.

487521:OCU RS27980
gene id: 487521:OCU_RS27980
uniprot id: H8IPC0
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS48755
gene id: 487521:OCU_RS48755
uniprot id: H8IIA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS32840
gene id: 487521:OCU_RS32840
uniprot id: H8IMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

487521:OCU RS42475
gene id: 487521:OCU_RS42475
uniprot id: H8II15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

487521:OCU RS35215
gene id: 487521:OCU_RS35215
uniprot id: H8ITW8
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS43035
gene id: 487521:OCU_RS43035
uniprot id: H8IJ85
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS46885
gene id: 487521:OCU_RS46885
uniprot id: H8ITG9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

487521:OCU RS41510
gene id: 487521:OCU_RS41510
uniprot id: H8IV56
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS38095
gene id: 487521:OCU_RS38095
uniprot id: H8IMT8
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS29560
gene id: 487521:OCU_RS29560
uniprot id: H8ISU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

487521:OCU RS48695
gene id: 487521:OCU_RS48695
uniprot id: H8II96
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS25995
gene id: 487521:OCU_RS25995
uniprot id: H8IJP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

487521:OCU RS29665
gene id: 487521:OCU_RS29665
uniprot id: H8ITL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

487521:OCU RS47645
gene id: 487521:OCU_RS47645
uniprot id: H8IVA7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS26875
gene id: 487521:OCU_RS26875
uniprot id: H8IME0
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

487521:OCU RS38465
gene id: 487521:OCU_RS38465
uniprot id: H8INP6
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

487521:OCU RS45220
gene id: 487521:OCU_RS45220
uniprot id: H8IPV5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

487521:OCU RS47115
gene id: 487521:OCU_RS47115
uniprot id: H8IUB0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

487521:OCU RS38220
gene id: 487521:OCU_RS38220
uniprot id: H8IMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

487521:OCU RS46355
gene id: 487521:OCU_RS46355
uniprot id: H8ISH1
names: Similarity
messages: Belongs to the UPF0336 family.

487521:OCU RS41985
gene id: 487521:OCU_RS41985
uniprot id: H8IWT7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

487521:OCU RS40185
gene id: 487521:OCU_RS40185
uniprot id: H8ISB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

487521:OCU RS39155
gene id: 487521:OCU_RS39155
uniprot id: H8IPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS30485
gene id: 487521:OCU_RS30485
uniprot id: H8IVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

487521:OCU RS41425
gene id: 487521:OCU_RS41425
uniprot id: H8IV39
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS45700
gene id: 487521:OCU_RS45700
uniprot id: H8IQS7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

487521:OCU RS39130
gene id: 487521:OCU_RS39130
uniprot id: H8IPQ7
names: Similarity
messages: Belongs to the TlyA family.

487521:OCU RS46040
gene id: 487521:OCU_RS46040
uniprot id: H8IRM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

487521:OCU RS38160
gene id: 487521:OCU_RS38160
uniprot id: H8IMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

487521:OCU RS41845
gene id: 487521:OCU_RS41845
uniprot id: H8IW17
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS35440
gene id: 487521:OCU_RS35440
uniprot id: H8IUQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

487521:OCU RS25375
gene id: 487521:OCU_RS25375
uniprot id: H8IIG0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

487521:OCU RS39635
gene id: 487521:OCU_RS39635
uniprot id: H8IRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

487521:OCU RS29495
gene id: 487521:OCU_RS29495
uniprot id: H8IST5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS46750
gene id: 487521:OCU_RS46750
uniprot id: H8ITD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

487521:OCU RS46585
gene id: 487521:OCU_RS46585
uniprot id: H8ISL3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

487521:OCU RS42095
gene id: 487521:OCU_RS42095
uniprot id: H8IWV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

487521:OCU RS39790
gene id: 487521:OCU_RS39790
uniprot id: H8IRE7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS45365
gene id: 487521:OCU_RS45365
uniprot id: H8IPY4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

487521:OCU RS48150
gene id: 487521:OCU_RS48150
uniprot id: H8IWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

487521:OCU RS29300
gene id: 487521:OCU_RS29300
uniprot id: H8ISP5
names: Similarity
messages: Belongs to the MoaD family.

487521:OCU RS36755
gene id: 487521:OCU_RS36755
uniprot id: H8IIZ1
names: Similarity
messages: Belongs to the CobH/CbiC family.

487521:OCU RS46680
gene id: 487521:OCU_RS46680
uniprot id: H8ITC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS38690
gene id: 487521:OCU_RS38690
uniprot id: H8INU1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

487521:OCU RS48845
gene id: 487521:OCU_RS48845
uniprot id: H8IIC6
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS45560
gene id: 487521:OCU_RS45560
uniprot id: H8IQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

487521:OCU RS46255
gene id: 487521:OCU_RS46255
uniprot id: H8IRR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

487521:OCU RS41500
gene id: 487521:OCU_RS41500
uniprot id: H8IV54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

487521:OCU RS31535
gene id: 487521:OCU_RS31535
uniprot id: H8IHY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS35175
gene id: 487521:OCU_RS35175
uniprot id: H8ITW0
names: Similarity
messages: Belongs to the peptidase S51 family.

487521:OCU RS25385
gene id: 487521:OCU_RS25385
uniprot id: H8IIG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS46030
gene id: 487521:OCU_RS46030
uniprot id: H8IRM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

487521:OCU RS33505
gene id: 487521:OCU_RS33505
uniprot id: H8IPF9
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS31585
gene id: 487521:OCU_RS31585
uniprot id: H8IIN5
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS27375
gene id: 487521:OCU_RS27375
uniprot id: H8INB6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

487521:OCU RS40480
gene id: 487521:OCU_RS40480
uniprot id: H8IT62
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

487521:OCU RS41705
gene id: 487521:OCU_RS41705
uniprot id: H8IVY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

487521:OCU RS25845
gene id: 487521:OCU_RS25845
uniprot id: H8IJL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

487521:OCU RS47710
gene id: 487521:OCU_RS47710
uniprot id: H8IVC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

487521:OCU RS43220
gene id: 487521:OCU_RS43220
uniprot id: H8IK98
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

487521:OCU RS43865
gene id: 487521:OCU_RS43865
uniprot id: H8ILJ7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

487521:OCU RS40135
gene id: 487521:OCU_RS40135
uniprot id: H8ISA6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS25465
gene id: 487521:OCU_RS25465
uniprot id: H8III0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

487521:OCU RS29555
gene id: 487521:OCU_RS29555
uniprot id: H8ISU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

487521:OCU RS39865
gene id: 487521:OCU_RS39865
uniprot id: H8IRG4
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

487521:OCU RS31510
gene id: 487521:OCU_RS31510
uniprot id: H8IHX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS36650
gene id: 487521:OCU_RS36650
uniprot id: H8IIX0
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

487521:OCU RS44055
gene id: 487521:OCU_RS44055
uniprot id: H8IM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

487521:OCU RS34970
gene id: 487521:OCU_RS34970
uniprot id: H8IT23
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

487521:OCU RS47355
gene id: 487521:OCU_RS47355
uniprot id: H8IUF7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

487521:OCU RS38175
gene id: 487521:OCU_RS38175
uniprot id: H8IMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

487521:OCU RS45595
gene id: 487521:OCU_RS45595
uniprot id: H8IQQ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS35045
gene id: 487521:OCU_RS35045
uniprot id: H8IT40
names: Similarity
messages: Belongs to the peptidase U62 family.

487521:OCU RS41875
gene id: 487521:OCU_RS41875
uniprot id: H8IW23
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

487521:OCU RS36655
gene id: 487521:OCU_RS36655
uniprot id: H8IIX1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

487521:OCU RS49560
gene id: 487521:OCU_RS49560
uniprot id: H8IKK1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS40655
gene id: 487521:OCU_RS40655
uniprot id: H8IT97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

487521:OCU RS40635
gene id: 487521:OCU_RS40635
uniprot id: H8IT93
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

487521:OCU RS48420
gene id: 487521:OCU_RS48420
uniprot id: H8IX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

487521:OCU RS31900
gene id: 487521:OCU_RS31900
uniprot id: H8IIV0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS40765
gene id: 487521:OCU_RS40765
uniprot id: H8ITC2
names: Similarity
messages: Belongs to the peptidase A24 family.

487521:OCU RS25805
gene id: 487521:OCU_RS25805
uniprot id: H8IJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

487521:OCU RS25420
gene id: 487521:OCU_RS25420
uniprot id: H8IIG9
names: Subcellular Location Annotation
messages: Cytoplasm

487521:OCU RS49075
gene id: 487521:OCU_RS49075
uniprot id: H8IJC7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS43765
gene id: 487521:OCU_RS43765
uniprot id: H8ILH6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

487521:OCU RS45885
gene id: 487521:OCU_RS45885
uniprot id: H8IRJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

487521:OCU RS46775
gene id: 487521:OCU_RS46775
uniprot id: H8ITE5
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS45640
gene id: 487521:OCU_RS45640
uniprot id: H8IQR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

487521:OCU RS40340
gene id: 487521:OCU_RS40340
uniprot id: H8ISE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

487521:OCU RS38150
gene id: 487521:OCU_RS38150
uniprot id: H8IMU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

487521:OCU RS37975
gene id: 487521:OCU_RS37975
uniprot id: H8IM39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

487521:OCU RS26120
gene id: 487521:OCU_RS26120
uniprot id: H8IKP2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS30025
gene id: 487521:OCU_RS30025
uniprot id: H8IUH9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS33885
gene id: 487521:OCU_RS33885
uniprot id: H8IQC1
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS41645
gene id: 487521:OCU_RS41645
uniprot id: H8IVX5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

487521:OCU RS38725
gene id: 487521:OCU_RS38725
uniprot id: H8INU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46160
gene id: 487521:OCU_RS46160
uniprot id: H8IRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

487521:OCU RS25765
gene id: 487521:OCU_RS25765
uniprot id: H8IJJ7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

487521:OCU RS39585
gene id: 487521:OCU_RS39585
uniprot id: H8IQM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

487521:OCU RS38295
gene id: 487521:OCU_RS38295
uniprot id: H8IMY0
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS47160
gene id: 487521:OCU_RS47160
uniprot id: H8IUB9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

487521:OCU RS38350
gene id: 487521:OCU_RS38350
uniprot id: H8IMZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

487521:OCU RS48915
gene id: 487521:OCU_RS48915
uniprot id: H8IIE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS34535
gene id: 487521:OCU_RS34535
uniprot id: H8IS44
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

487521:OCU RS36915
gene id: 487521:OCU_RS36915
uniprot id: H8IJ23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS29320
gene id: 487521:OCU_RS29320
uniprot id: H8ISP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS31215
gene id: 487521:OCU_RS31215
uniprot id: H8IHR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

487521:OCU RS41415
gene id: 487521:OCU_RS41415
uniprot id: H8IV37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS36210
gene id: 487521:OCU_RS36210
uniprot id: H8IVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

487521:OCU RS47030
gene id: 487521:OCU_RS47030
uniprot id: H8ITK0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

487521:OCU RS27005
gene id: 487521:OCU_RS27005
uniprot id: H8IMG7
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

487521:OCU RS33670
gene id: 487521:OCU_RS33670
uniprot id: H8IPJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane

487521:OCU RS43795
gene id: 487521:OCU_RS43795
uniprot id: H8ILI2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

487521:OCU RS45550
gene id: 487521:OCU_RS45550
uniprot id: H8IQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

487521:OCU RS41720
gene id: 487521:OCU_RS41720
uniprot id: H8IVZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

487521:OCU RS25655
gene id: 487521:OCU_RS25655
uniprot id: H8IIM1
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS35545
gene id: 487521:OCU_RS35545
uniprot id: H8IUS7
names: Subcellular Location Annotation
messages: Cell membrane

487521:OCU RS36665
gene id: 487521:OCU_RS36665
uniprot id: H8IIX3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

487521:OCU RS33300
gene id: 487521:OCU_RS33300
uniprot id: H8INM5
names: Similarity
messages: Belongs to the AccD/PCCB family.

487521:OCU RS42955
gene id: 487521:OCU_RS42955
uniprot id: H8IJ69
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

487521:OCU RS43350
gene id: 487521:OCU_RS43350
uniprot id: H8IKC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS37040
gene id: 487521:OCU_RS37040
uniprot id: H8IK21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

487521:OCU RS35295
gene id: 487521:OCU_RS35295
uniprot id: H8ITY4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS40105
gene id: 487521:OCU_RS40105
uniprot id: H8IS98
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

487521:OCU RS36500
gene id: 487521:OCU_RS36500
uniprot id: H8IWQ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS32870
gene id: 487521:OCU_RS32870
uniprot id: H8IMP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS43355
gene id: 487521:OCU_RS43355
uniprot id: H8IKC5
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS49745
gene id: 487521:OCU_RS49745
uniprot id: H8ILK7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

487521:OCU RS28865
gene id: 487521:OCU_RS28865
uniprot id: H8IRS8
names: Similarity
messages: Belongs to the HIBADH-related family.

487521:OCU RS35970
gene id: 487521:OCU_RS35970
uniprot id: H8IVQ3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

487521:OCU RS40965
gene id: 487521:OCU_RS40965
uniprot id: H8IU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

487521:OCU RS49260
gene id: 487521:OCU_RS49260
uniprot id: H8IJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

487521:OCU RS37485
gene id: 487521:OCU_RS37485
uniprot id: H8IL83
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS32690
gene id: 487521:OCU_RS32690
uniprot id: H8IL39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

487521:OCU RS49145
gene id: 487521:OCU_RS49145
uniprot id: H8IJE1
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS30790
gene id: 487521:OCU_RS30790
uniprot id: H8IVM1
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS42035
gene id: 487521:OCU_RS42035
uniprot id: H8IWU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS33540
gene id: 487521:OCU_RS33540
uniprot id: H8IPG6
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS33875
gene id: 487521:OCU_RS33875
uniprot id: H8IQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

487521:OCU RS45200
gene id: 487521:OCU_RS45200
uniprot id: H8IPV1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS47745
gene id: 487521:OCU_RS47745
uniprot id: H8IVC8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

487521:OCU RS27380
gene id: 487521:OCU_RS27380
uniprot id: H8INB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS37735
gene id: 487521:OCU_RS37735
uniprot id: H8ILY9
names: Similarity
messages: Belongs to the CinA family.

487521:OCU RS48245
gene id: 487521:OCU_RS48245
uniprot id: H8IX18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS36195
gene id: 487521:OCU_RS36195
uniprot id: H8IVV0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS32360
gene id: 487521:OCU_RS32360
uniprot id: H8IKX0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

487521:OCU RS36215
gene id: 487521:OCU_RS36215
uniprot id: H8IVV4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS36225
gene id: 487521:OCU_RS36225
uniprot id: H8IWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

487521:OCU RS25630
gene id: 487521:OCU_RS25630
uniprot id: H8IIL6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS33860
gene id: 487521:OCU_RS33860
uniprot id: H8IQB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

487521:OCU RS39480
gene id: 487521:OCU_RS39480
uniprot id: H8IQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

487521:OCU RS33495
gene id: 487521:OCU_RS33495
uniprot id: H8IPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

487521:OCU RS48480
gene id: 487521:OCU_RS48480
uniprot id: H8IX70
names: Similarity
messages: Belongs to the TPP enzyme family.

487521:OCU RS43845
gene id: 487521:OCU_RS43845
uniprot id: H8ILJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS37545
gene id: 487521:OCU_RS37545
uniprot id: H8IL96
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS47580
gene id: 487521:OCU_RS47580
uniprot id: H8IV92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS40415
gene id: 487521:OCU_RS40415
uniprot id: H8IT48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

487521:OCU RS35035
gene id: 487521:OCU_RS35035
uniprot id: H8IT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS33680
gene id: 487521:OCU_RS33680
uniprot id: H8IPJ2
names: Similarity
messages: Belongs to the YoeB family.

487521:OCU RS28190
gene id: 487521:OCU_RS28190
uniprot id: H8IQ38
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

487521:OCU RS29125
gene id: 487521:OCU_RS29125
uniprot id: H8IRY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

487521:OCU RS32200
gene id: 487521:OCU_RS32200
uniprot id: H8IJW5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS29175
gene id: 487521:OCU_RS29175
uniprot id: H8IRZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

487521:OCU RS31230
gene id: 487521:OCU_RS31230
uniprot id: H8IHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

487521:OCU RS41180
gene id: 487521:OCU_RS41180
uniprot id: H8IUY7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

487521:OCU RS26820
gene id: 487521:OCU_RS26820
uniprot id: H8ILW7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS44535
gene id: 487521:OCU_RS44535
uniprot id: H8IN61
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

487521:OCU RS39340
gene id: 487521:OCU_RS39340
uniprot id: H8IQH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

487521:OCU RS32945
gene id: 487521:OCU_RS32945
uniprot id: H8IMR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS25010
gene id: 487521:OCU_RS25010
uniprot id: H8IHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

487521:OCU RS37795
gene id: 487521:OCU_RS37795
uniprot id: H8IM01
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS40395
gene id: 487521:OCU_RS40395
uniprot id: H8IT44
names: Similarity
messages: Belongs to the histone deacetylase family.

487521:OCU RS42815
gene id: 487521:OCU_RS42815
uniprot id: H8IJ40
names: Similarity
messages: Belongs to the WrbA family.

487521:OCU RS47325
gene id: 487521:OCU_RS47325
uniprot id: H8IUF1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

487521:OCU RS28240
gene id: 487521:OCU_RS28240
uniprot id: H8IQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

487521:OCU RS39700
gene id: 487521:OCU_RS39700
uniprot id: H8IRC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS49410
gene id: 487521:OCU_RS49410
uniprot id: H8IKG9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS42720
gene id: 487521:OCU_RS42720
uniprot id: H8II66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

487521:OCU RS39645
gene id: 487521:OCU_RS39645
uniprot id: H8IRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

487521:OCU RS28065
gene id: 487521:OCU_RS28065
uniprot id: H8IQ12
names: Similarity
messages: Belongs to the SAICAR synthetase family.

487521:OCU RS28315
gene id: 487521:OCU_RS28315
uniprot id: H8IQ62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

487521:OCU RS48165
gene id: 487521:OCU_RS48165
uniprot id: H8IWA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

487521:OCU RS32765
gene id: 487521:OCU_RS32765
uniprot id: H8IMM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

487521:OCU RS44485
gene id: 487521:OCU_RS44485
uniprot id: H8IN50
names: Similarity
messages: Belongs to the isochorismate synthase family.

487521:OCU RS45650
gene id: 487521:OCU_RS45650
uniprot id: H8IQR7
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS46755
gene id: 487521:OCU_RS46755
uniprot id: H8ITE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

487521:OCU RS34565
gene id: 487521:OCU_RS34565
uniprot id: H8IS51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS49455
gene id: 487521:OCU_RS49455
uniprot id: H8IKH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS36165
gene id: 487521:OCU_RS36165
uniprot id: H8IVU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

487521:OCU RS26495
gene id: 487521:OCU_RS26495
uniprot id: H8ILQ1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

487521:OCU RS45070
gene id: 487521:OCU_RS45070
uniprot id: H8IP52
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

487521:OCU RS30215
gene id: 487521:OCU_RS30215
uniprot id: H8IUL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

487521:OCU RS49550
gene id: 487521:OCU_RS49550
uniprot id: H8IKJ9
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS33280
gene id: 487521:OCU_RS33280
uniprot id: H8INM1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS30505
gene id: 487521:OCU_RS30505
uniprot id: H8IVG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS47660
gene id: 487521:OCU_RS47660
uniprot id: H8IVB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

487521:OCU RS42215
gene id: 487521:OCU_RS42215
uniprot id: H8IWY3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS37450
gene id: 487521:OCU_RS37450
uniprot id: H8IL75
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS34030
gene id: 487521:OCU_RS34030
uniprot id: H8IR43
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

487521:OCU RS33205
gene id: 487521:OCU_RS33205
uniprot id: H8INK6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS40740
gene id: 487521:OCU_RS40740
uniprot id: H8ITB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

487521:OCU RS28455
gene id: 487521:OCU_RS28455
uniprot id: H8IQW4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS28325
gene id: 487521:OCU_RS28325
uniprot id: H8IQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

487521:OCU RS27535
gene id: 487521:OCU_RS27535
uniprot id: H8INF0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS38930
gene id: 487521:OCU_RS38930
uniprot id: H8IPL5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

487521:OCU RS45545
gene id: 487521:OCU_RS45545
uniprot id: H8IQP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

487521:OCU RS40705
gene id: 487521:OCU_RS40705
uniprot id: H8ITA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS40385
gene id: 487521:OCU_RS40385
uniprot id: H8IT42
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

487521:OCU RS44110
gene id: 487521:OCU_RS44110
uniprot id: H8IMA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

487521:OCU RS29365
gene id: 487521:OCU_RS29365
uniprot id: H8ISQ8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

487521:OCU RS49080
gene id: 487521:OCU_RS49080
uniprot id: H8IJC8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

487521:OCU RS39535
gene id: 487521:OCU_RS39535
uniprot id: H8IQL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

487521:OCU RS46795
gene id: 487521:OCU_RS46795
uniprot id: H8ITE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS48705
gene id: 487521:OCU_RS48705
uniprot id: H8II98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS26475
gene id: 487521:OCU_RS26475
uniprot id: H8IKW2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS40780
gene id: 487521:OCU_RS40780
uniprot id: H8IU16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

487521:OCU RS45680
gene id: 487521:OCU_RS45680
uniprot id: H8IQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

487521:OCU RS32165
gene id: 487521:OCU_RS32165
uniprot id: H8IJV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS34545
gene id: 487521:OCU_RS34545
uniprot id: H8IS46
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS27130
gene id: 487521:OCU_RS27130
uniprot id: H8IMJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

487521:OCU RS47010
gene id: 487521:OCU_RS47010
uniprot id: H8ITJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS26195
gene id: 487521:OCU_RS26195
uniprot id: H8IKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

487521:OCU RS34910
gene id: 487521:OCU_RS34910
uniprot id: H8IT12
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS45975
gene id: 487521:OCU_RS45975
uniprot id: H8IRL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

487521:OCU RS49245
gene id: 487521:OCU_RS49245
uniprot id: H8IJG2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

487521:OCU RS38125
gene id: 487521:OCU_RS38125
uniprot id: H8IMU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

487521:OCU RS49740
gene id: 487521:OCU_RS49740
uniprot id: H8IKN6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

487521:OCU RS43300
gene id: 487521:OCU_RS43300
uniprot id: H8IKB4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

487521:OCU RS30750
gene id: 487521:OCU_RS30750
uniprot id: H8IVL3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS41435
gene id: 487521:OCU_RS41435
uniprot id: H8IV41
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS42415
gene id: 487521:OCU_RS42415
uniprot id: H8II03
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

487521:OCU RS26745
gene id: 487521:OCU_RS26745
uniprot id: H8ILV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS46065
gene id: 487521:OCU_RS46065
uniprot id: H8IRM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

487521:OCU RS47415
gene id: 487521:OCU_RS47415
uniprot id: H8IUH0
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS26770
gene id: 487521:OCU_RS26770
uniprot id: H8ILV7
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

487521:OCU RS26725
gene id: 487521:OCU_RS26725
uniprot id: H8ILU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

487521:OCU RS41165
gene id: 487521:OCU_RS41165
uniprot id: H8IU94
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

487521:OCU RS47040
gene id: 487521:OCU_RS47040
uniprot id: H8ITK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

487521:OCU RS40550
gene id: 487521:OCU_RS40550
uniprot id: H8IT76
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

487521:OCU RS43495
gene id: 487521:OCU_RS43495
uniprot id: H8IKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

487521:OCU RS33690
gene id: 487521:OCU_RS33690
uniprot id: H8IPJ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

487521:OCU RS43245
gene id: 487521:OCU_RS43245
uniprot id: H8IKA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS47175
gene id: 487521:OCU_RS47175
uniprot id: H8IUC2
names: Similarity
messages: Belongs to the MmpS family.

487521:OCU RS38720
gene id: 487521:OCU_RS38720
uniprot id: H8INU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS48490
gene id: 487521:OCU_RS48490
uniprot id: H8IX72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.
messages: Probable oxidase that might be involved in lipid metabolism.

487521:OCU RS35025
gene id: 487521:OCU_RS35025
uniprot id: H8IT36
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

487521:OCU RS39095
gene id: 487521:OCU_RS39095
uniprot id: H8IPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

487521:OCU RS25900
gene id: 487521:OCU_RS25900
uniprot id: H8IJM5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS32900
gene id: 487521:OCU_RS32900
uniprot id: H8IMQ1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS43285
gene id: 487521:OCU_RS43285
uniprot id: H8IKB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS47225
gene id: 487521:OCU_RS47225
uniprot id: H8IUD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS45250
gene id: 487521:OCU_RS45250
uniprot id: H8IPW1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

487521:OCU RS28910
gene id: 487521:OCU_RS28910
uniprot id: H8IRT7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

487521:OCU RS43910
gene id: 487521:OCU_RS43910
uniprot id: H8ILK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS25410
gene id: 487521:OCU_RS25410
uniprot id: H8IIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS43695
gene id: 487521:OCU_RS43695
uniprot id: H8ILG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

487521:OCU RS42695
gene id: 487521:OCU_RS42695
uniprot id: H8II61
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS31225
gene id: 487521:OCU_RS31225
uniprot id: H8IHR6
names: Similarity
messages: Belongs to the peptidase S1C family.

487521:OCU RS28555
gene id: 487521:OCU_RS28555
uniprot id: H8IQY5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS48990
gene id: 487521:OCU_RS48990
uniprot id: H8IJA9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

487521:OCU RS37070
gene id: 487521:OCU_RS37070
uniprot id: H8IK27
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

487521:OCU RS43225
gene id: 487521:OCU_RS43225
uniprot id: H8IK99
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

487521:OCU RS30170
gene id: 487521:OCU_RS30170
uniprot id: H8IUK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

487521:OCU RS39425
gene id: 487521:OCU_RS39425
uniprot id: H8IQJ2
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS40525
gene id: 487521:OCU_RS40525
uniprot id: H8IT71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Homopentamer.

487521:OCU RS25645
gene id: 487521:OCU_RS25645
uniprot id: H8IIL9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

487521:OCU RS37840
gene id: 487521:OCU_RS37840
uniprot id: H8IM12
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS47545
gene id: 487521:OCU_RS47545
uniprot id: H8IV84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

487521:OCU RS33045
gene id: 487521:OCU_RS33045
uniprot id: H8INH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Siderophore-Fe(3+) uptake transporter (SIUT) (TC 3.A.1.21) family.
messages: Cell inner membrane
messages: Forms a heterodimer with IrtB.

487521:OCU RS44735
gene id: 487521:OCU_RS44735
uniprot id: H8INY4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

487521:OCU RS44885
gene id: 487521:OCU_RS44885
uniprot id: H8IP14
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS38285
gene id: 487521:OCU_RS38285
uniprot id: H8IMX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

487521:OCU RS31300
gene id: 487521:OCU_RS31300
uniprot id: H8IHT1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

487521:OCU RS41895
gene id: 487521:OCU_RS41895
uniprot id: H8IW27
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS33095
gene id: 487521:OCU_RS33095
uniprot id: H8INI4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS30795
gene id: 487521:OCU_RS30795
uniprot id: H8IVM2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS43105
gene id: 487521:OCU_RS43105
uniprot id: H8IJ98
names: Similarity
messages: Belongs to the DNA photolyase family.

487521:OCU RS35200
gene id: 487521:OCU_RS35200
uniprot id: H8ITW5
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS46260
gene id: 487521:OCU_RS46260
uniprot id: H8IRS0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS41535
gene id: 487521:OCU_RS41535
uniprot id: H8IV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

487521:OCU RS33000
gene id: 487521:OCU_RS33000
uniprot id: H8IMS3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

487521:OCU RS36355
gene id: 487521:OCU_RS36355
uniprot id: H8IWM4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS36520
gene id: 487521:OCU_RS36520
uniprot id: H8IWQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS45385
gene id: 487521:OCU_RS45385
uniprot id: H8IPY8
names: Similarity
messages: Belongs to the CFA/CMAS family.

487521:OCU RS43850
gene id: 487521:OCU_RS43850
uniprot id: H8ILJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS39260
gene id: 487521:OCU_RS39260
uniprot id: H8IQF8
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

487521:OCU RS35975
gene id: 487521:OCU_RS35975
uniprot id: H8IVQ4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

487521:OCU RS49225
gene id: 487521:OCU_RS49225
uniprot id: H8IJF7
names: Similarity
messages: Belongs to the manganese catalase family.

487521:OCU RS30405
gene id: 487521:OCU_RS30405
uniprot id: H8IUQ4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS44260
gene id: 487521:OCU_RS44260
uniprot id: H8IMD1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

487521:OCU RS43100
gene id: 487521:OCU_RS43100
uniprot id: H8IJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

487521:OCU RS45255
gene id: 487521:OCU_RS45255
uniprot id: H8IPW2
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

487521:OCU RS29630
gene id: 487521:OCU_RS29630
uniprot id: H8ITK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS38040
gene id: 487521:OCU_RS38040
uniprot id: H8IM54
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

487521:OCU RS48190
gene id: 487521:OCU_RS48190
uniprot id: H8IWB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

487521:OCU RS28950
gene id: 487521:OCU_RS28950
uniprot id: H8IRU5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS39750
gene id: 487521:OCU_RS39750
uniprot id: H8IRD7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS47310
gene id: 487521:OCU_RS47310
uniprot id: H8IUE8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS36980
gene id: 487521:OCU_RS36980
uniprot id: H8IK08
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS45230
gene id: 487521:OCU_RS45230
uniprot id: H8IPV7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS30525
gene id: 487521:OCU_RS30525
uniprot id: H8IVG7
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS37335
gene id: 487521:OCU_RS37335
uniprot id: H8IL49
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

487521:OCU RS34490
gene id: 487521:OCU_RS34490
uniprot id: H8IS35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS47100
gene id: 487521:OCU_RS47100
uniprot id: H8IUA7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

487521:OCU RS41855
gene id: 487521:OCU_RS41855
uniprot id: H8IW19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

487521:OCU RS31315
gene id: 487521:OCU_RS31315
uniprot id: H8IHT4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS32770
gene id: 487521:OCU_RS32770
uniprot id: H8IMM8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

487521:OCU RS37660
gene id: 487521:OCU_RS37660
uniprot id: H8ILC1
names: Similarity
messages: Belongs to the AHA1 family.

487521:OCU RS26210
gene id: 487521:OCU_RS26210
uniprot id: H8IKR0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS44725
gene id: 487521:OCU_RS44725
uniprot id: H8INY2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

487521:OCU RS32775
gene id: 487521:OCU_RS32775
uniprot id: H8IMM9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

487521:OCU RS37230
gene id: 487521:OCU_RS37230
uniprot id: H8IK59
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS40870
gene id: 487521:OCU_RS40870
uniprot id: H8IU34
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS46345
gene id: 487521:OCU_RS46345
uniprot id: H8ISG9
names: Similarity
messages: Belongs to the UPF0336 family.

487521:OCU RS37905
gene id: 487521:OCU_RS37905
uniprot id: H8IM25
names: Subcellular Location Annotation
messages: Cytoplasm

487521:OCU RS34870
gene id: 487521:OCU_RS34870
uniprot id: H8IT04
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

487521:OCU RS49890
gene id: 487521:OCU_RS49890
uniprot id: H8ILN5
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS34935
gene id: 487521:OCU_RS34935
uniprot id: H8IT17
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

487521:OCU RS28330
gene id: 487521:OCU_RS28330
uniprot id: H8IQ65
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

487521:OCU RS26350
gene id: 487521:OCU_RS26350
uniprot id: H8IKT7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS40160
gene id: 487521:OCU_RS40160
uniprot id: H8ISB1
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS45150
gene id: 487521:OCU_RS45150
uniprot id: H8IPU1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS39980
gene id: 487521:OCU_RS39980
uniprot id: H8IRI8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS30445
gene id: 487521:OCU_RS30445
uniprot id: H8IVF0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS25005
gene id: 487521:OCU_RS25005
uniprot id: H8IHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

487521:OCU RS27785
gene id: 487521:OCU_RS27785
uniprot id: H8IP81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS45745
gene id: 487521:OCU_RS45745
uniprot id: H8IQT7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

487521:OCU RS32695
gene id: 487521:OCU_RS32695
uniprot id: H8IL40
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

487521:OCU RS46430
gene id: 487521:OCU_RS46430
uniprot id: H8ISI4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

487521:OCU RS46880
gene id: 487521:OCU_RS46880
uniprot id: H8ITG8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

487521:OCU RS43750
gene id: 487521:OCU_RS43750
uniprot id: B7T031
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS35460
gene id: 487521:OCU_RS35460
uniprot id: H8IUR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS26450
gene id: 487521:OCU_RS26450
uniprot id: H8IKV7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS30950
gene id: 487521:OCU_RS30950
uniprot id: H8IWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

487521:OCU RS40420
gene id: 487521:OCU_RS40420
uniprot id: H8IT49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

487521:OCU RS38835
gene id: 487521:OCU_RS38835
uniprot id: H8INX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS35000
gene id: 487521:OCU_RS35000
uniprot id: H8IT30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

487521:OCU RS44335
gene id: 487521:OCU_RS44335
uniprot id: H8IN19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS49815
gene id: 487521:OCU_RS49815
uniprot id: H8ILM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

487521:OCU RS31950
gene id: 487521:OCU_RS31950
uniprot id: H8IJR5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS30450
gene id: 487521:OCU_RS30450
uniprot id: H8IVF1
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

487521:OCU RS27225
gene id: 487521:OCU_RS27225
uniprot id: H8IML1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS27270
gene id: 487521:OCU_RS27270
uniprot id: H8IN95
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

487521:OCU RS28150
gene id: 487521:OCU_RS28150
uniprot id: H8IQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

487521:OCU RS32255
gene id: 487521:OCU_RS32255
uniprot id: H8IJX7
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS45995
gene id: 487521:OCU_RS45995
uniprot id: H8IRL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

487521:OCU RS30465
gene id: 487521:OCU_RS30465
uniprot id: H8IVF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

487521:OCU RS43405
gene id: 487521:OCU_RS43405
uniprot id: H8IKD5
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

487521:OCU RS38255
gene id: 487521:OCU_RS38255
uniprot id: H8IMX0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS44540
gene id: 487521:OCU_RS44540
uniprot id: H8IN62
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS29740
gene id: 487521:OCU_RS29740
uniprot id: H8ITM6
names: Similarity
messages: Belongs to the AccD/PCCB family.

487521:OCU RS25890
gene id: 487521:OCU_RS25890
uniprot id: H8IJM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

487521:OCU RS31725
gene id: 487521:OCU_RS31725
uniprot id: H8IIR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS48590
gene id: 487521:OCU_RS48590
uniprot id: H8II74
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS49465
gene id: 487521:OCU_RS49465
uniprot id: H8IKI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS32035
gene id: 487521:OCU_RS32035
uniprot id: H8IJT2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

487521:OCU RS29460
gene id: 487521:OCU_RS29460
uniprot id: H8ISS8
names: Subcellular Location Annotation
messages: Cell membrane

487521:OCU RS27600
gene id: 487521:OCU_RS27600
uniprot id: H8ING3
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS25170
gene id: 487521:OCU_RS25170
uniprot id: H8IHM6
names: Similarity
messages: Belongs to the pirin family.

487521:OCU RS25835
gene id: 487521:OCU_RS25835
uniprot id: H8IJL1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS46015
gene id: 487521:OCU_RS46015
uniprot id: H8IRL8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

487521:OCU RS37790
gene id: 487521:OCU_RS37790
uniprot id: H8IM00
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS30150
gene id: 487521:OCU_RS30150
uniprot id: H8IUK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

487521:OCU RS42265
gene id: 487521:OCU_RS42265
uniprot id: H8IWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

487521:OCU RS47150
gene id: 487521:OCU_RS47150
uniprot id: H8IUB7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS29565
gene id: 487521:OCU_RS29565
uniprot id: H8ISU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

487521:OCU RS29880
gene id: 487521:OCU_RS29880
uniprot id: H8ITQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

487521:OCU RS43385
gene id: 487521:OCU_RS43385
uniprot id: H8IKD1
names: Similarity
messages: Belongs to the MmpS family.

487521:OCU RS29295
gene id: 487521:OCU_RS29295
uniprot id: H8ISP4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

487521:OCU RS42985
gene id: 487521:OCU_RS42985
uniprot id: H8IJ75
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

487521:OCU RS40615
gene id: 487521:OCU_RS40615
uniprot id: H8IT89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

487521:OCU RS43160
gene id: 487521:OCU_RS43160
uniprot id: H8IK83
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

487521:OCU RS42735
gene id: 487521:OCU_RS42735
uniprot id: H8IJ26
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

487521:OCU RS27030
gene id: 487521:OCU_RS27030
uniprot id: H8IMH2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS34835
gene id: 487521:OCU_RS34835
uniprot id: H8ISZ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

487521:OCU RS28260
gene id: 487521:OCU_RS28260
uniprot id: H8IQ52
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS40010
gene id: 487521:OCU_RS40010
uniprot id: H8IS77
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

487521:OCU RS36380
gene id: 487521:OCU_RS36380
uniprot id: H8IWN0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

487521:OCU RS39805
gene id: 487521:OCU_RS39805
uniprot id: H8IRF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

487521:OCU RS44700
gene id: 487521:OCU_RS44700
uniprot id: H8INX6
names: Similarity
messages: Belongs to the thymidylate kinase family.

487521:OCU RS39810
gene id: 487521:OCU_RS39810
uniprot id: H8IRF1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS40920
gene id: 487521:OCU_RS40920
uniprot id: H8IU44
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

487521:OCU RS30060
gene id: 487521:OCU_RS30060
uniprot id: H8IUI6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS48550
gene id: 487521:OCU_RS48550
uniprot id: H8IX86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

487521:OCU RS45990
gene id: 487521:OCU_RS45990
uniprot id: H8IRL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

487521:OCU RS30100
gene id: 487521:OCU_RS30100
uniprot id: H8IUJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

487521:OCU RS42610
gene id: 487521:OCU_RS42610
uniprot id: H8II42
names: Similarity
messages: Belongs to the TPP enzyme family.

487521:OCU RS29745
gene id: 487521:OCU_RS29745
uniprot id: H8ITM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS28075
gene id: 487521:OCU_RS28075
uniprot id: H8IQ14
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS28820
gene id: 487521:OCU_RS28820
uniprot id: H8IR40
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS42040
gene id: 487521:OCU_RS42040
uniprot id: H8IWU8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

487521:OCU RS48440
gene id: 487521:OCU_RS48440
uniprot id: H8IX62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS34435
gene id: 487521:OCU_RS34435
uniprot id: H8IS24
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS25905
gene id: 487521:OCU_RS25905
uniprot id: H8IJM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

487521:OCU RS42480
gene id: 487521:OCU_RS42480
uniprot id: H8II16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

487521:OCU RS44465
gene id: 487521:OCU_RS44465
uniprot id: H8IN46
names: Similarity
messages: Belongs to the DEAD box helicase family.

487521:OCU RS36620
gene id: 487521:OCU_RS36620
uniprot id: H8IIW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

487521:OCU RS42740
gene id: 487521:OCU_RS42740
uniprot id: H8IJ27
names: Similarity
messages: Belongs to the Nudix hydrolase family.

487521:OCU RS46690
gene id: 487521:OCU_RS46690
uniprot id: H8ITC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

487521:OCU RS35455
gene id: 487521:OCU_RS35455
uniprot id: H8IUQ9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

487521:OCU RS27200
gene id: 487521:OCU_RS27200
uniprot id: H8IMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

487521:OCU RS37765
gene id: 487521:OCU_RS37765
uniprot id: H8ILZ5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

487521:OCU RS27310
gene id: 487521:OCU_RS27310
uniprot id: H8INA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS47330
gene id: 487521:OCU_RS47330
uniprot id: H8IUF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

487521:OCU RS25750
gene id: 487521:OCU_RS25750
uniprot id: H8IJJ4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS25070
gene id: 487521:OCU_RS25070
uniprot id: H8IHK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

487521:OCU RS26220
gene id: 487521:OCU_RS26220
uniprot id: H8IKR2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

487521:OCU RS33545
gene id: 487521:OCU_RS33545
uniprot id: H8IPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

487521:OCU RS34755
gene id: 487521:OCU_RS34755
uniprot id: H8ISY1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

487521:OCU RS46815
gene id: 487521:OCU_RS46815
uniprot id: H8ITF3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

487521:OCU RS45340
gene id: 487521:OCU_RS45340
uniprot id: H8IPX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS47345
gene id: 487521:OCU_RS47345
uniprot id: H8IUF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

487521:OCU RS49590
gene id: 487521:OCU_RS49590
uniprot id: H8IKK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS39855
gene id: 487521:OCU_RS39855
uniprot id: H8IRG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS36020
gene id: 487521:OCU_RS36020
uniprot id: H8IVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

487521:OCU RS40495
gene id: 487521:OCU_RS40495
uniprot id: H8IT65
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

487521:OCU RS25365
gene id: 487521:OCU_RS25365
uniprot id: H8IIF8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS40490
gene id: 487521:OCU_RS40490
uniprot id: H8IT64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

487521:OCU RS46770
gene id: 487521:OCU_RS46770
uniprot id: H8ITE4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS26510
gene id: 487521:OCU_RS26510
uniprot id: H8ILQ4
names: Similarity
messages: Belongs to the PrpD family.

487521:OCU RS48095
gene id: 487521:OCU_RS48095
uniprot id: H8IW95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

487521:OCU RS45105
gene id: 487521:OCU_RS45105
uniprot id: H8IPT3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

487521:OCU RS46330
gene id: 487521:OCU_RS46330
uniprot id: H8ISG7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

487521:OCU RS34420
gene id: 487521:OCU_RS34420
uniprot id: H8IS20
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS45630
gene id: 487521:OCU_RS45630
uniprot id: H8IQR3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

487521:OCU RS44075
gene id: 487521:OCU_RS44075
uniprot id: H8IM93
names: Similarity
messages: Belongs to the TPP enzyme family.

487521:OCU RS42180
gene id: 487521:OCU_RS42180
uniprot id: H8IWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

487521:OCU RS42670
gene id: 487521:OCU_RS42670
uniprot id: H8II56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS32010
gene id: 487521:OCU_RS32010
uniprot id: H8IJS7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS39270
gene id: 487521:OCU_RS39270
uniprot id: H8IQG0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS29730
gene id: 487521:OCU_RS29730
uniprot id: H8ITM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46490
gene id: 487521:OCU_RS46490
uniprot id: H8ISJ6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

487521:OCU RS35760
gene id: 487521:OCU_RS35760
uniprot id: H8IUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

487521:OCU RS46830
gene id: 487521:OCU_RS46830
uniprot id: H8ITF6
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS40720
gene id: 487521:OCU_RS40720
uniprot id: H8ITB1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

487521:OCU RS39675
gene id: 487521:OCU_RS39675
uniprot id: H8IRC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

487521:OCU RS32340
gene id: 487521:OCU_RS32340
uniprot id: H8IKW5
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

487521:OCU RS26785
gene id: 487521:OCU_RS26785
uniprot id: H8ILW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

487521:OCU RS32305
gene id: 487521:OCU_RS32305
uniprot id: H8IJY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS31345
gene id: 487521:OCU_RS31345
uniprot id: H8IHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

487521:OCU RS39920
gene id: 487521:OCU_RS39920
uniprot id: H8IRH5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS49615
gene id: 487521:OCU_RS49615
uniprot id: H8IKL2
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS40605
gene id: 487521:OCU_RS40605
uniprot id: H8IT87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

487521:OCU RS25190
gene id: 487521:OCU_RS25190
uniprot id: H8IHN0
names: Similarity
messages: Belongs to the peptidase C40 family.

487521:OCU RS34065
gene id: 487521:OCU_RS34065
uniprot id: H8IR50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

487521:OCU RS34005
gene id: 487521:OCU_RS34005
uniprot id: H8IQE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS39525
gene id: 487521:OCU_RS39525
uniprot id: H8IQL4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

487521:OCU RS28815
gene id: 487521:OCU_RS28815
uniprot id: H8IR39
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS29960
gene id: 487521:OCU_RS29960
uniprot id: H8ITS4
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS49310
gene id: 487521:OCU_RS49310
uniprot id: H8IJH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

487521:OCU RS37000
gene id: 487521:OCU_RS37000
uniprot id: H8IK13
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

487521:OCU RS44850
gene id: 487521:OCU_RS44850
uniprot id: H8IP07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

487521:OCU RS43985
gene id: 487521:OCU_RS43985
uniprot id: H8IM75
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

487521:OCU RS39305
gene id: 487521:OCU_RS39305
uniprot id: H8IQG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

487521:OCU RS33020
gene id: 487521:OCU_RS33020
uniprot id: H8IMS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

487521:OCU RS33460
gene id: 487521:OCU_RS33460
uniprot id: H8IPE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

487521:OCU RS45540
gene id: 487521:OCU_RS45540
uniprot id: H8IQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

487521:OCU RS28020
gene id: 487521:OCU_RS28020
uniprot id: H8IPC8
names: Similarity
messages: Belongs to the GARS family.

487521:OCU RS33085
gene id: 487521:OCU_RS33085
uniprot id: H8INI2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS41665
gene id: 487521:OCU_RS41665
uniprot id: H8IVY1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

487521:OCU RS35525
gene id: 487521:OCU_RS35525
uniprot id: H8IUS3
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS49070
gene id: 487521:OCU_RS49070
uniprot id: H8IJC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS32510
gene id: 487521:OCU_RS32510
uniprot id: H8IL01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS41030
gene id: 487521:OCU_RS41030
uniprot id: H8IU67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS38205
gene id: 487521:OCU_RS38205
uniprot id: H8IMW0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS29645
gene id: 487521:OCU_RS29645
uniprot id: H8ITK7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

487521:OCU RS25450
gene id: 487521:OCU_RS25450
uniprot id: H8IIH6
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS35050
gene id: 487521:OCU_RS35050
uniprot id: H8IT41
names: Similarity
messages: Belongs to the peptidase U62 family.

487521:OCU RS25390
gene id: 487521:OCU_RS25390
uniprot id: H8IIG3
names: Similarity
messages: Belongs to the MmpS family.

487521:OCU RS25960
gene id: 487521:OCU_RS25960
uniprot id: H8IJN8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

487521:OCU RS49365
gene id: 487521:OCU_RS49365
uniprot id: H8IKG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS27085
gene id: 487521:OCU_RS27085
uniprot id: H8IMI3
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS28235
gene id: 487521:OCU_RS28235
uniprot id: H8IQ47
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

487521:OCU RS46410
gene id: 487521:OCU_RS46410
uniprot id: H8ISI0
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

487521:OCU RS41715
gene id: 487521:OCU_RS41715
uniprot id: H8IVZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS25325
gene id: 487521:OCU_RS25325
uniprot id: H8IIF0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

487521:OCU RS34795
gene id: 487521:OCU_RS34795
uniprot id: H8ISY9
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

487521:OCU RS42585
gene id: 487521:OCU_RS42585
uniprot id: H8II37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

487521:OCU RS42975
gene id: 487521:OCU_RS42975
uniprot id: H8IJ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

487521:OCU RS42745
gene id: 487521:OCU_RS42745
uniprot id: A0A1Y0DT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial histone-like protein family.
messages: cell wall

487521:OCU RS33750
gene id: 487521:OCU_RS33750
uniprot id: H8IQ94
names: Similarity
messages: Belongs to the LacAB/RpiB family.

487521:OCU RS29265
gene id: 487521:OCU_RS29265
uniprot id: H8ISN8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

487521:OCU RS43395
gene id: 487521:OCU_RS43395
uniprot id: H8IKD3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS37750
gene id: 487521:OCU_RS37750
uniprot id: H8ILZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS30015
gene id: 487521:OCU_RS30015
uniprot id: H8IUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

487521:OCU RS32845
gene id: 487521:OCU_RS32845
uniprot id: H8IMP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

487521:OCU RS27610
gene id: 487521:OCU_RS27610
uniprot id: H8ING5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS48660
gene id: 487521:OCU_RS48660
uniprot id: H8II88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

487521:OCU RS48690
gene id: 487521:OCU_RS48690
uniprot id: H8II94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

487521:OCU RS48345
gene id: 487521:OCU_RS48345
uniprot id: H8IX41
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

487521:OCU RS42155
gene id: 487521:OCU_RS42155
uniprot id: H8IWX1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

487521:OCU RS43665
gene id: 487521:OCU_RS43665
uniprot id: H8ILF5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS27520
gene id: 487521:OCU_RS27520
uniprot id: H8INE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS43860
gene id: 487521:OCU_RS43860
uniprot id: H8ILJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

487521:OCU RS27580
gene id: 487521:OCU_RS27580
uniprot id: H8INF9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS41630
gene id: 487521:OCU_RS41630
uniprot id: H8IVX2
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS30815
gene id: 487521:OCU_RS30815
uniprot id: H8IWB9
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS25625
gene id: 487521:OCU_RS25625
uniprot id: H8IIL5
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS30105
gene id: 487521:OCU_RS30105
uniprot id: H8IUJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS42935
gene id: 487521:OCU_RS42935
uniprot id: H8IJ65
names: Similarity
messages: Belongs to the AHA1 family.

487521:OCU RS45210
gene id: 487521:OCU_RS45210
uniprot id: H8IPV3
names: Similarity
messages: Belongs to the peptidase S11 family.

487521:OCU RS33740
gene id: 487521:OCU_RS33740
uniprot id: H8IQ92
names: Similarity
messages: Belongs to the peptidase M1 family.

487521:OCU RS46925
gene id: 487521:OCU_RS46925
uniprot id: H8ITH8
names: Similarity
messages: Belongs to the UPF0336 family.

487521:OCU RS38315
gene id: 487521:OCU_RS38315
uniprot id: H8IMY4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS31320
gene id: 487521:OCU_RS31320
uniprot id: H8IHT5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.

487521:OCU RS27055
gene id: 487521:OCU_RS27055
uniprot id: H8IMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

487521:OCU RS25855
gene id: 487521:OCU_RS25855
uniprot id: H8IJL6
names: Similarity
messages: Belongs to the glutamate synthase family.

487521:OCU RS39320
gene id: 487521:OCU_RS39320
uniprot id: H8IQH0
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS42455
gene id: 487521:OCU_RS42455
uniprot id: H8II11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

487521:OCU RS45180
gene id: 487521:OCU_RS45180
uniprot id: H8IPU7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

487521:OCU RS31790
gene id: 487521:OCU_RS31790
uniprot id: H8IIS8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS28575
gene id: 487521:OCU_RS28575
uniprot id: H8IQZ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS28620
gene id: 487521:OCU_RS28620
uniprot id: H8IR00
names: Function
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.
messages: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).

487521:OCU RS26310
gene id: 487521:OCU_RS26310
uniprot id: H8IKS7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS38005
gene id: 487521:OCU_RS38005
uniprot id: H8IM45
names: Similarity
messages: Belongs to the Apa family.

487521:OCU RS35705
gene id: 487521:OCU_RS35705
uniprot id: H8IUW0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

487521:OCU RS43330
gene id: 487521:OCU_RS43330
uniprot id: H8IKC0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS35595
gene id: 487521:OCU_RS35595
uniprot id: H8IUT8
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS35040
gene id: 487521:OCU_RS35040
uniprot id: H8IT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS25680
gene id: 487521:OCU_RS25680
uniprot id: H8IIM6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

487521:OCU RS36025
gene id: 487521:OCU_RS36025
uniprot id: H8IVR5
names: Similarity
messages: Belongs to the MmpS family.

487521:OCU RS49620
gene id: 487521:OCU_RS49620
uniprot id: H8IKL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

487521:OCU RS48815
gene id: 487521:OCU_RS48815
uniprot id: H8IIC0
names: Similarity
messages: Belongs to the pirin family.

487521:OCU RS44045
gene id: 487521:OCU_RS44045
uniprot id: H8IM87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

487521:OCU RS31985
gene id: 487521:OCU_RS31985
uniprot id: H8IJS2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS45020
gene id: 487521:OCU_RS45020
uniprot id: H8IP42
names: Similarity
messages: Belongs to the FPG family.

487521:OCU RS48375
gene id: 487521:OCU_RS48375
uniprot id: H8IX48
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS45225
gene id: 487521:OCU_RS45225
uniprot id: H8IPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

487521:OCU RS27255
gene id: 487521:OCU_RS27255
uniprot id: H8IML8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

487521:OCU RS36710
gene id: 487521:OCU_RS36710
uniprot id: H8IIY2
names: Similarity
messages: Belongs to the peptidase M24B family.

487521:OCU RS38865
gene id: 487521:OCU_RS38865
uniprot id: H8IPK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS39820
gene id: 487521:OCU_RS39820
uniprot id: H8IRF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane

487521:OCU RS40305
gene id: 487521:OCU_RS40305
uniprot id: H8ISE0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

487521:OCU RS38090
gene id: 487521:OCU_RS38090
uniprot id: H8IMT7
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS35265
gene id: 487521:OCU_RS35265
uniprot id: H8ITX8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS33830
gene id: 487521:OCU_RS33830
uniprot id: H8IQB0
names: Similarity
messages: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily.

487521:OCU RS38270
gene id: 487521:OCU_RS38270
uniprot id: H8IMX5
names: Similarity
messages: Belongs to the EccE family.

487521:OCU RS45480
gene id: 487521:OCU_RS45480
uniprot id: H8IQ08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

487521:OCU RS44605
gene id: 487521:OCU_RS44605
uniprot id: H8IN76
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

487521:OCU RS49040
gene id: 487521:OCU_RS49040
uniprot id: H8IJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

487521:OCU RS35955
gene id: 487521:OCU_RS35955
uniprot id: H8IVQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

487521:OCU RS39620
gene id: 487521:OCU_RS39620
uniprot id: H8IRB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS34830
gene id: 487521:OCU_RS34830
uniprot id: H8ISZ6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

487521:OCU RS37015
gene id: 487521:OCU_RS37015
uniprot id: H8IK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS47640
gene id: 487521:OCU_RS47640
uniprot id: H8IVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

487521:OCU RS27305
gene id: 487521:OCU_RS27305
uniprot id: H8INA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS34965
gene id: 487521:OCU_RS34965
uniprot id: H8IT22
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

487521:OCU RS37995
gene id: 487521:OCU_RS37995
uniprot id: H8IM43
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS31155
gene id: 487521:OCU_RS31155
uniprot id: H8IWJ2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

487521:OCU RS28900
gene id: 487521:OCU_RS28900
uniprot id: H8IRT5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS38230
gene id: 487521:OCU_RS38230
uniprot id: H8IMW5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS27495
gene id: 487521:OCU_RS27495
uniprot id: H8INE2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

487521:OCU RS25250
gene id: 487521:OCU_RS25250
uniprot id: H8IHP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS30925
gene id: 487521:OCU_RS30925
uniprot id: H8IWE4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

487521:OCU RS34125
gene id: 487521:OCU_RS34125
uniprot id: H8IR63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

487521:OCU RS36140
gene id: 487521:OCU_RS36140
uniprot id: H8IVT9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

487521:OCU RS49535
gene id: 487521:OCU_RS49535
uniprot id: H8IKJ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

487521:OCU RS29635
gene id: 487521:OCU_RS29635
uniprot id: H8ITK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

487521:OCU RS30125
gene id: 487521:OCU_RS30125
uniprot id: H8IUK0
names: Similarity
messages: Belongs to the ArsC family.

487521:OCU RS42185
gene id: 487521:OCU_RS42185
uniprot id: H8IWX7
names: Similarity
messages: Belongs to the peptidase A31 family.

487521:OCU RS40995
gene id: 487521:OCU_RS40995
uniprot id: H8IU60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

487521:OCU RS39670
gene id: 487521:OCU_RS39670
uniprot id: H8IRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

487521:OCU RS39895
gene id: 487521:OCU_RS39895
uniprot id: H8IRH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

487521:OCU RS46320
gene id: 487521:OCU_RS46320
uniprot id: H8ISG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

487521:OCU RS32615
gene id: 487521:OCU_RS32615
uniprot id: H8IL23
names: Subcellular Location Annotation
messages: Cell membrane

487521:OCU RS44175
gene id: 487521:OCU_RS44175
uniprot id: H8IMB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS33185
gene id: 487521:OCU_RS33185
uniprot id: H8INK2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

487521:OCU RS35965
gene id: 487521:OCU_RS35965
uniprot id: H8IVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

487521:OCU RS29000
gene id: 487521:OCU_RS29000
uniprot id: H8IRV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46900
gene id: 487521:OCU_RS46900
uniprot id: H8ITH2
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS30210
gene id: 487521:OCU_RS30210
uniprot id: H8IUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

487521:OCU RS39775
gene id: 487521:OCU_RS39775
uniprot id: H8IRE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

487521:OCU RS30565
gene id: 487521:OCU_RS30565
uniprot id: H8IVH5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

487521:OCU RS28995
gene id: 487521:OCU_RS28995
uniprot id: H8IRV4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS45045
gene id: 487521:OCU_RS45045
uniprot id: H8IP47
names: Similarity
messages: Belongs to the mycobacterial PPE family.

487521:OCU RS39380
gene id: 487521:OCU_RS39380
uniprot id: H8IQI2
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS42005
gene id: 487521:OCU_RS42005
uniprot id: H8IWU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

487521:OCU RS40260
gene id: 487521:OCU_RS40260
uniprot id: H8ISD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS34840
gene id: 487521:OCU_RS34840
uniprot id: H8ISZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

487521:OCU RS25175
gene id: 487521:OCU_RS25175
uniprot id: H8IHM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46485
gene id: 487521:OCU_RS46485
uniprot id: H8ISJ5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

487521:OCU RS25025
gene id: 487521:OCU_RS25025
uniprot id: H8IHK0
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

487521:OCU RS39685
gene id: 487521:OCU_RS39685
uniprot id: H8IRC4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

487521:OCU RS45410
gene id: 487521:OCU_RS45410
uniprot id: H8IPZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

487521:OCU RS26525
gene id: 487521:OCU_RS26525
uniprot id: H8ILQ7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

487521:OCU RS42175
gene id: 487521:OCU_RS42175
uniprot id: H8IWX5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

487521:OCU RS25775
gene id: 487521:OCU_RS25775
uniprot id: H8IJJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS32790
gene id: 487521:OCU_RS32790
uniprot id: H8IMN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

487521:OCU RS40020
gene id: 487521:OCU_RS40020
uniprot id: H8IS80
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

487521:OCU RS46035
gene id: 487521:OCU_RS46035
uniprot id: H8IRM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

487521:OCU RS39615
gene id: 487521:OCU_RS39615
uniprot id: H8IRB0
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS35365
gene id: 487521:OCU_RS35365
uniprot id: H8ITZ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

487521:OCU RS40425
gene id: 487521:OCU_RS40425
uniprot id: H8IT50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

487521:OCU RS45645
gene id: 487521:OCU_RS45645
uniprot id: H8IQR6
names: Similarity
messages: Belongs to the WXG100 family.

487521:OCU RS49605
gene id: 487521:OCU_RS49605
uniprot id: H8IKL0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS33355
gene id: 487521:OCU_RS33355
uniprot id: H8INN5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

487521:OCU RS46060
gene id: 487521:OCU_RS46060
uniprot id: H8IRM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

487521:OCU RS44380
gene id: 487521:OCU_RS44380
uniprot id: H8IN28
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

487521:OCU RS45260
gene id: 487521:OCU_RS45260
uniprot id: H8IPW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

487521:OCU RS43630
gene id: 487521:OCU_RS43630
uniprot id: H8ILE8
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

487521:OCU RS35195
gene id: 487521:OCU_RS35195
uniprot id: H8ITW4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

487521:OCU RS45400
gene id: 487521:OCU_RS45400
uniprot id: H8IPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm

487521:OCU RS44035
gene id: 487521:OCU_RS44035
uniprot id: H8IM85
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS37375
gene id: 487521:OCU_RS37375
uniprot id: H8IL58
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

487521:OCU RS40875
gene id: 487521:OCU_RS40875
uniprot id: H8IU35
names: Similarity
messages: Belongs to the DapA family.

487521:OCU RS34905
gene id: 487521:OCU_RS34905
uniprot id: H8IT11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS39605
gene id: 487521:OCU_RS39605
uniprot id: H8IQN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

487521:OCU RS38970
gene id: 487521:OCU_RS38970
uniprot id: H8IPM3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

487521:OCU RS49905
gene id: 487521:OCU_RS49905
uniprot id: H8ILN8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

487521:OCU RS37755
gene id: 487521:OCU_RS37755
uniprot id: H8ILZ3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

487521:OCU RS39490
gene id: 487521:OCU_RS39490
uniprot id: H8IQK7
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

487521:OCU RS39235
gene id: 487521:OCU_RS39235
uniprot id: H8IQF3
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

487521:OCU RS34770
gene id: 487521:OCU_RS34770
uniprot id: H8ISY4
names: Similarity
messages: Belongs to the thioesterase family.

487521:OCU RS40935
gene id: 487521:OCU_RS40935
uniprot id: H8IU47
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

487521:OCU RS33060
gene id: 487521:OCU_RS33060
uniprot id: H8INH7
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

487521:OCU RS41580
gene id: 487521:OCU_RS41580
uniprot id: H8IVW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

487521:OCU RS28110
gene id: 487521:OCU_RS28110
uniprot id: H8IQ21
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

487521:OCU RS27420
gene id: 487521:OCU_RS27420
uniprot id: H8INC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

487521:OCU RS45090
gene id: 487521:OCU_RS45090
uniprot id: H8IPT0
names: Similarity
messages: Belongs to the peptidase M20A family.

487521:OCU RS29445
gene id: 487521:OCU_RS29445
uniprot id: H8ISS5
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

487521:OCU RS42560
gene id: 487521:OCU_RS42560
uniprot id: H8II32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

487521:OCU RS44405
gene id: 487521:OCU_RS44405
uniprot id: H8IN34
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

487521:OCU RS39070
gene id: 487521:OCU_RS39070
uniprot id: H8IPP5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

487521:OCU RS32850
gene id: 487521:OCU_RS32850
uniprot id: H8IMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

487521:OCU RS28750
gene id: 487521:OCU_RS28750
uniprot id: H8IR26
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

487521:OCU RS40745
gene id: 487521:OCU_RS40745
uniprot id: H8ITB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

487521:OCU RS31120
gene id: 487521:OCU_RS31120
uniprot id: H8IWI5
names: Subcellular Location Annotation
messages: Membrane

487521:OCU RS41880
gene id: 487521:OCU_RS41880
uniprot id: H8IW24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

487521:OCU RS31270
gene id: 487521:OCU_RS31270
uniprot id: H8IHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

487521:OCU RS46820
gene id: 487521:OCU_RS46820
uniprot id: H8ITF4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
messages: Binds 1 phosphopantetheine covalently.
messages: Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.