48664:PD885 RS15050
gene id: 48664:PD885_RS15050
uniprot id: A0A1Y6HAQ8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

48664:PD885 RS10170
gene id: 48664:PD885_RS10170
uniprot id: A0A1Y6HCZ0
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

48664:PD885 RS04540
gene id: 48664:PD885_RS04540
uniprot id: A0A1Y6HQ18
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

48664:PD885 RS15610
gene id: 48664:PD885_RS15610
uniprot id: A0A1Y6GYU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

48664:PD885 RS10845
gene id: 48664:PD885_RS10845
uniprot id: A0A1Y6H8B4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

48664:PD885 RS03630
gene id: 48664:PD885_RS03630
uniprot id: A0A1Y6GV35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

48664:PD885 RS18305
gene id: 48664:PD885_RS18305
uniprot id: A0A1Y6HC23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

48664:PD885 RS05775
gene id: 48664:PD885_RS05775
uniprot id: A0A1Y6H5H7
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

48664:PD885 RS07735
gene id: 48664:PD885_RS07735
uniprot id: A0A1Y6HAF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

48664:PD885 RS13830
gene id: 48664:PD885_RS13830
uniprot id: A0A1Y6H908
names: Similarity
messages: Belongs to the aldose epimerase family.

48664:PD885 RS01550
gene id: 48664:PD885_RS01550
uniprot id: A0A1Y6H6V6
names: Similarity
messages: Belongs to the TrpC family.

48664:PD885 RS17640
gene id: 48664:PD885_RS17640
uniprot id: A0A1Y6HB81
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

48664:PD885 RS14930
gene id: 48664:PD885_RS14930
uniprot id: A0A1Y6HCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

48664:PD885 RS09005
gene id: 48664:PD885_RS09005
uniprot id: A0A1Y6H9U8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

48664:PD885 RS06395
gene id: 48664:PD885_RS06395
uniprot id: A0A1Y6H9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS09090
gene id: 48664:PD885_RS09090
uniprot id: A0A1Y6GUZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

48664:PD885 RS04030
gene id: 48664:PD885_RS04030
uniprot id: A0A1Y6HLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

48664:PD885 RS00995
gene id: 48664:PD885_RS00995
uniprot id: A0A1Y6H4L9
names: Similarity
messages: Belongs to the catalase family.

48664:PD885 RS14990
gene id: 48664:PD885_RS14990
uniprot id: A0A1Y6H9N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

48664:PD885 RS02605
gene id: 48664:PD885_RS02605
uniprot id: A0A1Y6GRL4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

48664:PD885 RS06990
gene id: 48664:PD885_RS06990
uniprot id: A0A1Y6H551
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

48664:PD885 RS02005
gene id: 48664:PD885_RS02005
uniprot id: A0A1Y6H3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

48664:PD885 RS06090
gene id: 48664:PD885_RS06090
uniprot id: A0A1Y6H1H6
names: Similarity
messages: Belongs to the GSP E family.

48664:PD885 RS13355
gene id: 48664:PD885_RS13355
uniprot id: A0A1Y6H8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

48664:PD885 RS01585
gene id: 48664:PD885_RS01585
uniprot id: A0A1Y6H029
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

48664:PD885 RS12525
gene id: 48664:PD885_RS12525
uniprot id: A0A1Y6H8A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

48664:PD885 RS14590
gene id: 48664:PD885_RS14590
uniprot id: A0A1Y6H9I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

48664:PD885 RS05545
gene id: 48664:PD885_RS05545
uniprot id: A0A1Y6H4C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

48664:PD885 RS11500
gene id: 48664:PD885_RS11500
uniprot id: A0A1Y6HAH8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

48664:PD885 RS07165
gene id: 48664:PD885_RS07165
uniprot id: A0A1Y6H6C2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS09605
gene id: 48664:PD885_RS09605
uniprot id: A0A1Y6HLS3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

48664:PD885 RS06045
gene id: 48664:PD885_RS06045
uniprot id: A0A1Y6GXV0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

48664:PD885 RS11240
gene id: 48664:PD885_RS11240
uniprot id: A0A1Y6H7Y0
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

48664:PD885 RS08485
gene id: 48664:PD885_RS08485
uniprot id: A0A1Y6H721
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

48664:PD885 RS14585
gene id: 48664:PD885_RS14585
uniprot id: A0A1Y6HGB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

48664:PD885 RS12665
gene id: 48664:PD885_RS12665
uniprot id: A0A1Y6HB65
names: Similarity
messages: Belongs to the GST superfamily.

48664:PD885 RS00790
gene id: 48664:PD885_RS00790
uniprot id: A0A1Y6H4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

48664:PD885 RS13775
gene id: 48664:PD885_RS13775
uniprot id: A0A1Y6HDS0
names: Similarity
messages: Belongs to the HSP15 family.

48664:PD885 RS01210
gene id: 48664:PD885_RS01210
uniprot id: A0A1Y6H7V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

48664:PD885 RS08770
gene id: 48664:PD885_RS08770
uniprot id: A0A1Y6HIM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

48664:PD885 RS01295
gene id: 48664:PD885_RS01295
uniprot id: A0A1Y6H0U9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

48664:PD885 RS14710
gene id: 48664:PD885_RS14710
uniprot id: A0A1Y6HLS1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS14705
gene id: 48664:PD885_RS14705
uniprot id: A0A1Y6HFU2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

48664:PD885 RS10620
gene id: 48664:PD885_RS10620
uniprot id: A0A1Y6HAQ7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

48664:PD885 RS01985
gene id: 48664:PD885_RS01985
uniprot id: A0A1Y6HP19
names: Similarity
messages: Belongs to the CutA family.

48664:PD885 RS02115
gene id: 48664:PD885_RS02115
uniprot id: A0A1Y6HMV8
names: Function
names: Similarity
messages: Belongs to the MdcG family.
messages: Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].

48664:PD885 RS05445
gene id: 48664:PD885_RS05445
uniprot id: A0A1Y6H481
names: Similarity
messages: Belongs to the MoaD family.

48664:PD885 RS15220
gene id: 48664:PD885_RS15220
uniprot id: A0A1Y6HFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS00605
gene id: 48664:PD885_RS00605
uniprot id: A0A1Y6H2L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

48664:PD885 RS03640
gene id: 48664:PD885_RS03640
uniprot id: A0A1Y6GY52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

48664:PD885 RS00410
gene id: 48664:PD885_RS00410
uniprot id: A0A1Y6H1G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

48664:PD885 RS10970
gene id: 48664:PD885_RS10970
uniprot id: A0A1Y6H7D1
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS17630
gene id: 48664:PD885_RS17630
uniprot id: A0A1Y6HBP0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

48664:PD885 RS04420
gene id: 48664:PD885_RS04420
uniprot id: A0A1Y6H3M8
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS07765
gene id: 48664:PD885_RS07765
uniprot id: A0A1Y6GX89
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

48664:PD885 RS08440
gene id: 48664:PD885_RS08440
uniprot id: A0A1Y6HHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

48664:PD885 RS05855
gene id: 48664:PD885_RS05855
uniprot id: A0A1Y6H4F6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

48664:PD885 RS00005
gene id: 48664:PD885_RS00005
uniprot id: A0A1Y6HCU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

48664:PD885 RS04690
gene id: 48664:PD885_RS04690
uniprot id: A0A1Y6HMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS14665
gene id: 48664:PD885_RS14665
uniprot id: A0A1Y6HFK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

48664:PD885 RS14720
gene id: 48664:PD885_RS14720
uniprot id: A0A1Y6HFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

48664:PD885 RS09710
gene id: 48664:PD885_RS09710
uniprot id: A0A1Y6GVT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS09795
gene id: 48664:PD885_RS09795
uniprot id: A0A1Y6H0Q6
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS11720
gene id: 48664:PD885_RS11720
uniprot id: A0A1Y6H2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

48664:PD885 RS08740
gene id: 48664:PD885_RS08740
uniprot id: A0A1Y6H650
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

48664:PD885 RS19415
gene id: 48664:PD885_RS19415
uniprot id: A0A1Y6HC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

48664:PD885 RS01015
gene id: 48664:PD885_RS01015
uniprot id: A0A1Y6H1T6
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

48664:PD885 RS17435
gene id: 48664:PD885_RS17435
uniprot id: A0A1Y6HB44
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

48664:PD885 RS10040
gene id: 48664:PD885_RS10040
uniprot id: A0A1Y6HIF9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

48664:PD885 RS10335
gene id: 48664:PD885_RS10335
uniprot id: A0A1Y6H9V9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

48664:PD885 RS10350
gene id: 48664:PD885_RS10350
uniprot id: A0A1Y6GVH4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

48664:PD885 RS07775
gene id: 48664:PD885_RS07775
uniprot id: A0A1Y6H5J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS16860
gene id: 48664:PD885_RS16860
uniprot id: A0A1Y6HEN4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

48664:PD885 RS13800
gene id: 48664:PD885_RS13800
uniprot id: A0A1Y6GXE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

48664:PD885 RS08215
gene id: 48664:PD885_RS08215
uniprot id: A0A1Y6HHS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

48664:PD885 RS13725
gene id: 48664:PD885_RS13725
uniprot id: A0A1Y6HGD3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

48664:PD885 RS15270
gene id: 48664:PD885_RS15270
uniprot id: A0A1Y6HK95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

48664:PD885 RS05075
gene id: 48664:PD885_RS05075
uniprot id: A0A1Y6H433
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

48664:PD885 RS15370
gene id: 48664:PD885_RS15370
uniprot id: A0A1Y6HLE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

48664:PD885 RS08630
gene id: 48664:PD885_RS08630
uniprot id: A0A1Y6H629
names: Similarity
messages: Belongs to the glutathione peroxidase family.

48664:PD885 RS12920
gene id: 48664:PD885_RS12920
uniprot id: A0A1Y6HBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

48664:PD885 RS16155
gene id: 48664:PD885_RS16155
uniprot id: A0A1Y6GZN4
names: Similarity
messages: Belongs to the UPF0102 family.

48664:PD885 RS18535
gene id: 48664:PD885_RS18535
uniprot id: A0A1Y6HF98
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

48664:PD885 RS06405
gene id: 48664:PD885_RS06405
uniprot id: A0A1Y6HN66
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

48664:PD885 RS14060
gene id: 48664:PD885_RS14060
uniprot id: A0A1Y6H970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

48664:PD885 RS18290
gene id: 48664:PD885_RS18290
uniprot id: A0A1Y6HBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

48664:PD885 RS09610
gene id: 48664:PD885_RS09610
uniprot id: A0A1Y6H9F9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

48664:PD885 RS10850
gene id: 48664:PD885_RS10850
uniprot id: A0A1Y6HJA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

48664:PD885 RS03990
gene id: 48664:PD885_RS03990
uniprot id: A0A1Y6H9F1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

48664:PD885 RS16110
gene id: 48664:PD885_RS16110
uniprot id: A0A1Y6HAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

48664:PD885 RS02935
gene id: 48664:PD885_RS02935
uniprot id: A0A1Y6HTA5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

48664:PD885 RS09750
gene id: 48664:PD885_RS09750
uniprot id: A0A1Y6GYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

48664:PD885 RS05005
gene id: 48664:PD885_RS05005
uniprot id: A0A1Y6GSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS15465
gene id: 48664:PD885_RS15465
uniprot id: A0A1Y6HFE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane

48664:PD885 RS01145
gene id: 48664:PD885_RS01145
uniprot id: A0A1Y6HNV4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

48664:PD885 RS01255
gene id: 48664:PD885_RS01255
uniprot id: A0A1Y6H6P3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

48664:PD885 RS03445
gene id: 48664:PD885_RS03445
uniprot id: A0A1Y6HMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

48664:PD885 RS14535
gene id: 48664:PD885_RS14535
uniprot id: A0A1Y6H310
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

48664:PD885 RS14940
gene id: 48664:PD885_RS14940
uniprot id: A0A1Y6HFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

48664:PD885 RS18285
gene id: 48664:PD885_RS18285
uniprot id: A0A1Y6HER8
names: Similarity
messages: Belongs to the P(II) protein family.

48664:PD885 RS11375
gene id: 48664:PD885_RS11375
uniprot id: A0A1Y6H8L9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

48664:PD885 RS09425
gene id: 48664:PD885_RS09425
uniprot id: A0A1Y6H9B8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

48664:PD885 RS08060
gene id: 48664:PD885_RS08060
uniprot id: A0A1Y6HAK5
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS10750
gene id: 48664:PD885_RS10750
uniprot id: A0A1Y6GV92
names: Similarity
messages: Belongs to the ClpA/ClpB family.

48664:PD885 RS07330
gene id: 48664:PD885_RS07330
uniprot id: A0A1Y6HPS8
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS15420
gene id: 48664:PD885_RS15420
uniprot id: A0A1Y6HCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

48664:PD885 RS12090
gene id: 48664:PD885_RS12090
uniprot id: A0A1Y6GWR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

48664:PD885 RS08000
gene id: 48664:PD885_RS08000
uniprot id: A0A1Y6H9A2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

48664:PD885 RS14945
gene id: 48664:PD885_RS14945
uniprot id: A0A1Y6H9M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

48664:PD885 RS13485
gene id: 48664:PD885_RS13485
uniprot id: A0A1Y6H8V3
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS12180
gene id: 48664:PD885_RS12180
uniprot id: A0A1Y6HK19
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

48664:PD885 RS09920
gene id: 48664:PD885_RS09920
uniprot id: A0A1Y6HCU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS12160
gene id: 48664:PD885_RS12160
uniprot id: A0A1Y6H2N7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

48664:PD885 RS01915
gene id: 48664:PD885_RS01915
uniprot id: A0A1Y6H3G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

48664:PD885 RS09755
gene id: 48664:PD885_RS09755
uniprot id: A0A1Y6HKY8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

48664:PD885 RS02800
gene id: 48664:PD885_RS02800
uniprot id: A0A1Y6GWU3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

48664:PD885 RS02720
gene id: 48664:PD885_RS02720
uniprot id: A0A1Y6GSY6
names: Similarity
messages: Belongs to the pyruvate kinase family.

48664:PD885 RS18060
gene id: 48664:PD885_RS18060
uniprot id: A0A1Y6GRI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

48664:PD885 RS06080
gene id: 48664:PD885_RS06080
uniprot id: A0A1Y6HKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

48664:PD885 RS12495
gene id: 48664:PD885_RS12495
uniprot id: A0A1Y6H890
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS05115
gene id: 48664:PD885_RS05115
uniprot id: A0A1Y6HPS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

48664:PD885 RS16480
gene id: 48664:PD885_RS16480
uniprot id: A0A1Y6HAI3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS06175
gene id: 48664:PD885_RS06175
uniprot id: A0A1Y6H7I7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

48664:PD885 RS08760
gene id: 48664:PD885_RS08760
uniprot id: A0A1Y6GVI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

48664:PD885 RS02455
gene id: 48664:PD885_RS02455
uniprot id: A0A1Y6H2M8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

48664:PD885 RS15895
gene id: 48664:PD885_RS15895
uniprot id: A0A1Y6HF90
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS12300
gene id: 48664:PD885_RS12300
uniprot id: A0A1Y6H857
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS09080
gene id: 48664:PD885_RS09080
uniprot id: A0A1Y6H699
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

48664:PD885 RS09395
gene id: 48664:PD885_RS09395
uniprot id: A0A1Y6HIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

48664:PD885 RS12870
gene id: 48664:PD885_RS12870
uniprot id: A0A1Y6H8I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

48664:PD885 RS16350
gene id: 48664:PD885_RS16350
uniprot id: A0A1Y6HIE6
names: Similarity
messages: Belongs to the UPF0162 family.

48664:PD885 RS10090
gene id: 48664:PD885_RS10090
uniprot id: A0A1Y6H7X0
names: Similarity
messages: Belongs to the MotB family.

48664:PD885 RS01200
gene id: 48664:PD885_RS01200
uniprot id: A0A1Y6HNU6
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

48664:PD885 RS02925
gene id: 48664:PD885_RS02925
uniprot id: A0A1Y6H6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

48664:PD885 RS15115
gene id: 48664:PD885_RS15115
uniprot id: A0A1Y6HFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS14010
gene id: 48664:PD885_RS14010
uniprot id: A0A1Y6HCL8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

48664:PD885 RS03960
gene id: 48664:PD885_RS03960
uniprot id: A0A1Y6H3Y2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

48664:PD885 RS09790
gene id: 48664:PD885_RS09790
uniprot id: A0A1Y6H6R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

48664:PD885 RS13895
gene id: 48664:PD885_RS13895
uniprot id: A0A1Y6H939
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

48664:PD885 RS14130
gene id: 48664:PD885_RS14130
uniprot id: A0A1Y6H969
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

48664:PD885 RS01940
gene id: 48664:PD885_RS01940
uniprot id: A0A1Y6H580
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

48664:PD885 RS03245
gene id: 48664:PD885_RS03245
uniprot id: A0A1Y6GZV4
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

48664:PD885 RS10615
gene id: 48664:PD885_RS10615
uniprot id: A0A1Y6H771
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

48664:PD885 RS08915
gene id: 48664:PD885_RS08915
uniprot id: A0A1Y6HC91
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

48664:PD885 RS09230
gene id: 48664:PD885_RS09230
uniprot id: A0A1Y6HMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

48664:PD885 RS16580
gene id: 48664:PD885_RS16580
uniprot id: A0A1Y6HKQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

48664:PD885 RS18295
gene id: 48664:PD885_RS18295
uniprot id: A0A1Y6HCM1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

48664:PD885 RS12670
gene id: 48664:PD885_RS12670
uniprot id: A0A1Y6HJW3
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS10635
gene id: 48664:PD885_RS10635
uniprot id: A0A1Y6HPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS11005
gene id: 48664:PD885_RS11005
uniprot id: A0A1Y6HJW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

48664:PD885 RS15480
gene id: 48664:PD885_RS15480
uniprot id: A0A1Y6HG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS11475
gene id: 48664:PD885_RS11475
uniprot id: A0A1Y6GW76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

48664:PD885 RS18975
gene id: 48664:PD885_RS18975
uniprot id: A0A1Y6HGX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

48664:PD885 RS04085
gene id: 48664:PD885_RS04085
uniprot id: A0A1Y6H3H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

48664:PD885 RS03945
gene id: 48664:PD885_RS03945
uniprot id: A0A1Y6H3G2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

48664:PD885 RS02640
gene id: 48664:PD885_RS02640
uniprot id: A0A1Y6HNP0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS12170
gene id: 48664:PD885_RS12170
uniprot id: A0A1Y6GWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS02840
gene id: 48664:PD885_RS02840
uniprot id: A0A1Y6H2W0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

48664:PD885 RS04410
gene id: 48664:PD885_RS04410
uniprot id: A0A1Y6H4S9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

48664:PD885 RS12130
gene id: 48664:PD885_RS12130
uniprot id: A0A1Y6HJM4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS04035
gene id: 48664:PD885_RS04035
uniprot id: A0A1Y6HSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

48664:PD885 RS01300
gene id: 48664:PD885_RS01300
uniprot id: A0A1Y6H4T4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

48664:PD885 RS08465
gene id: 48664:PD885_RS08465
uniprot id: A0A1Y6HM98
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

48664:PD885 RS01565
gene id: 48664:PD885_RS01565
uniprot id: A0A1Y6H246
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

48664:PD885 RS18545
gene id: 48664:PD885_RS18545
uniprot id: A0A1Y6HEL5
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

48664:PD885 RS05390
gene id: 48664:PD885_RS05390
uniprot id: A0A1Y6HPM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

48664:PD885 RS17230
gene id: 48664:PD885_RS17230
uniprot id: A0A1Y6HHW7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

48664:PD885 RS11560
gene id: 48664:PD885_RS11560
uniprot id: A0A1Y6HCK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

48664:PD885 RS11415
gene id: 48664:PD885_RS11415
uniprot id: A0A1Y6HJM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

48664:PD885 RS07650
gene id: 48664:PD885_RS07650
uniprot id: A0A1Y6GUZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS09535
gene id: 48664:PD885_RS09535
uniprot id: A0A1Y6HP33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

48664:PD885 RS18175
gene id: 48664:PD885_RS18175
uniprot id: A0A1Y6HGC0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

48664:PD885 RS03865
gene id: 48664:PD885_RS03865
uniprot id: A0A1Y6HM22
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

48664:PD885 RS03675
gene id: 48664:PD885_RS03675
uniprot id: A0A1Y6H399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

48664:PD885 RS13025
gene id: 48664:PD885_RS13025
uniprot id: A0A1Y6HDD7
names: Similarity
messages: Belongs to the asparagine synthetase family.

48664:PD885 RS06895
gene id: 48664:PD885_RS06895
uniprot id: A0A1Y6HK63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

48664:PD885 RS16665
gene id: 48664:PD885_RS16665
uniprot id: A0A1Y6HAN2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS16875
gene id: 48664:PD885_RS16875
uniprot id: A0A1Y6HAS9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

48664:PD885 RS16845
gene id: 48664:PD885_RS16845
uniprot id: A0A1Y6HAS6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

48664:PD885 RS15785
gene id: 48664:PD885_RS15785
uniprot id: A0A1Y6HA48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

48664:PD885 RS18945
gene id: 48664:PD885_RS18945
uniprot id: A0A1Y6HCE7
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS12945
gene id: 48664:PD885_RS12945
uniprot id: A0A1Y6H9I9
names: Similarity
messages: Belongs to the HIBADH-related family.

48664:PD885 RS11390
gene id: 48664:PD885_RS11390
uniprot id: A0A1Y6H7N2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

48664:PD885 RS01780
gene id: 48664:PD885_RS01780
uniprot id: A0A1Y6HP57
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

48664:PD885 RS12085
gene id: 48664:PD885_RS12085
uniprot id: A0A1Y6H917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

48664:PD885 RS18255
gene id: 48664:PD885_RS18255
uniprot id: A0A1Y6HBK8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

48664:PD885 RS09560
gene id: 48664:PD885_RS09560
uniprot id: A0A1Y6H6K8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

48664:PD885 RS17160
gene id: 48664:PD885_RS17160
uniprot id: A0A1Y6HAZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

48664:PD885 RS17680
gene id: 48664:PD885_RS17680
uniprot id: A0A1Y6HB85
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

48664:PD885 RS01680
gene id: 48664:PD885_RS01680
uniprot id: A0A1Y6H268
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS00025
gene id: 48664:PD885_RS00025
uniprot id: A0A1Y6H186
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

48664:PD885 RS11395
gene id: 48664:PD885_RS11395
uniprot id: A0A1Y6HB66
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

48664:PD885 RS14465
gene id: 48664:PD885_RS14465
uniprot id: A0A1Y6H9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

48664:PD885 RS16530
gene id: 48664:PD885_RS16530
uniprot id: A0A1Y6GZD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

48664:PD885 RS13150
gene id: 48664:PD885_RS13150
uniprot id: A0A1Y6HGN0
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS13075
gene id: 48664:PD885_RS13075
uniprot id: A0A1Y6HHQ2
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS18065
gene id: 48664:PD885_RS18065
uniprot id: A0A1Y6GS16
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

48664:PD885 RS08795
gene id: 48664:PD885_RS08795
uniprot id: A0A1Y6H661
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS04745
gene id: 48664:PD885_RS04745
uniprot id: A0A1Y6H7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

48664:PD885 RS09745
gene id: 48664:PD885_RS09745
uniprot id: A0A1Y6H0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

48664:PD885 RS14515
gene id: 48664:PD885_RS14515
uniprot id: A0A1Y6HFH9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

48664:PD885 RS07925
gene id: 48664:PD885_RS07925
uniprot id: A0A1Y6GXB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS05630
gene id: 48664:PD885_RS05630
uniprot id: A0A1Y6H4V9
names: Similarity
messages: Belongs to the PrpF family.

48664:PD885 RS16490
gene id: 48664:PD885_RS16490
uniprot id: A0A1Y6HBJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

48664:PD885 RS12790
gene id: 48664:PD885_RS12790
uniprot id: A0A1Y6H037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

48664:PD885 RS13015
gene id: 48664:PD885_RS13015
uniprot id: A0A1Y6HC41
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

48664:PD885 RS05470
gene id: 48664:PD885_RS05470
uniprot id: A0A1Y6H498
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

48664:PD885 RS00230
gene id: 48664:PD885_RS00230
uniprot id: A0A1Y6GRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

48664:PD885 RS07105
gene id: 48664:PD885_RS07105
uniprot id: A0A1Y6H6B2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

48664:PD885 RS14445
gene id: 48664:PD885_RS14445
uniprot id: A0A1Y6HC77
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS07150
gene id: 48664:PD885_RS07150
uniprot id: A0A1Y6HMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS13255
gene id: 48664:PD885_RS13255
uniprot id: A0A1Y6HGL1
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

48664:PD885 RS03615
gene id: 48664:PD885_RS03615
uniprot id: A0A1Y6H821
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

48664:PD885 RS17550
gene id: 48664:PD885_RS17550
uniprot id: A0A1Y6HE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

48664:PD885 RS13420
gene id: 48664:PD885_RS13420
uniprot id: A0A1Y6HEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS17570
gene id: 48664:PD885_RS17570
uniprot id: A0A1Y6HB68
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

48664:PD885 RS00980
gene id: 48664:PD885_RS00980
uniprot id: A0A1Y6GTG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS19915
gene id: 48664:PD885_RS19915
uniprot id: A0A1Y6HUN4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

48664:PD885 RS15100
gene id: 48664:PD885_RS15100
uniprot id: A0A1Y6HG12
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

48664:PD885 RS16610
gene id: 48664:PD885_RS16610
uniprot id: A0A1Y6HAL1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

48664:PD885 RS08865
gene id: 48664:PD885_RS08865
uniprot id: A0A1Y6HC79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS15970
gene id: 48664:PD885_RS15970
uniprot id: A0A1Y6HF38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

48664:PD885 RS17250
gene id: 48664:PD885_RS17250
uniprot id: A0A1Y6HB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

48664:PD885 RS15730
gene id: 48664:PD885_RS15730
uniprot id: A0A1Y6H2J5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

48664:PD885 RS00595
gene id: 48664:PD885_RS00595
uniprot id: A0A1Y6H1K5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

48664:PD885 RS10695
gene id: 48664:PD885_RS10695
uniprot id: A0A1Y6H780
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

48664:PD885 RS12210
gene id: 48664:PD885_RS12210
uniprot id: A0A1Y6HBN3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

48664:PD885 RS12860
gene id: 48664:PD885_RS12860
uniprot id: A0A1Y6H8V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS03805
gene id: 48664:PD885_RS03805
uniprot id: A0A1Y6HM32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS02000
gene id: 48664:PD885_RS02000
uniprot id: A0A1Y6H2E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

48664:PD885 RS03980
gene id: 48664:PD885_RS03980
uniprot id: A0A1Y6H6B4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

48664:PD885 RS12335
gene id: 48664:PD885_RS12335
uniprot id: A0A1Y6H870
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

48664:PD885 RS03650
gene id: 48664:PD885_RS03650
uniprot id: A0A1Y6H6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

48664:PD885 RS16055
gene id: 48664:PD885_RS16055
uniprot id: A0A1Y6GZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

48664:PD885 RS12970
gene id: 48664:PD885_RS12970
uniprot id: A0A1Y6GU17
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

48664:PD885 RS17490
gene id: 48664:PD885_RS17490
uniprot id: A0A1Y6HGY1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

48664:PD885 RS14555
gene id: 48664:PD885_RS14555
uniprot id: A0A1Y6HLV6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

48664:PD885 RS01350
gene id: 48664:PD885_RS01350
uniprot id: A0A1Y6H4U8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

48664:PD885 RS04225
gene id: 48664:PD885_RS04225
uniprot id: A0A1Y6H6G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS18480
gene id: 48664:PD885_RS18480
uniprot id: A0A1Y6HGI2
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

48664:PD885 RS10955
gene id: 48664:PD885_RS10955
uniprot id: A0A1Y6HJV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

48664:PD885 RS13220
gene id: 48664:PD885_RS13220
uniprot id: A0A1Y6HBH3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

48664:PD885 RS03820
gene id: 48664:PD885_RS03820
uniprot id: A0A1Y6H681
names: Similarity
messages: Belongs to the DEAD box helicase family.

48664:PD885 RS18835
gene id: 48664:PD885_RS18835
uniprot id: A0A1Y6HBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

48664:PD885 RS15090
gene id: 48664:PD885_RS15090
uniprot id: A0A1Y6H9R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

48664:PD885 RS17785
gene id: 48664:PD885_RS17785
uniprot id: A0A1Y6GRP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

48664:PD885 RS05840
gene id: 48664:PD885_RS05840
uniprot id: A0A1Y6H9B9
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS09270
gene id: 48664:PD885_RS09270
uniprot id: A0A1Y6H6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

48664:PD885 RS18860
gene id: 48664:PD885_RS18860
uniprot id: A0A1Y6HGP7
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS05875
gene id: 48664:PD885_RS05875
uniprot id: A0A1Y6H4I4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

48664:PD885 RS02400
gene id: 48664:PD885_RS02400
uniprot id: A0A1Y6H2L7
names: Similarity
messages: Belongs to the manganese catalase family.

48664:PD885 RS00890
gene id: 48664:PD885_RS00890
uniprot id: A0A1Y6GWE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

48664:PD885 RS12615
gene id: 48664:PD885_RS12615
uniprot id: A0A1Y6HB58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS07885
gene id: 48664:PD885_RS07885
uniprot id: A0A1Y6H5M1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

48664:PD885 RS04255
gene id: 48664:PD885_RS04255
uniprot id: A0A1Y6H3J9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

48664:PD885 RS10030
gene id: 48664:PD885_RS10030
uniprot id: A0A1Y6H7W5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

48664:PD885 RS15850
gene id: 48664:PD885_RS15850
uniprot id: A0A1Y6HB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

48664:PD885 RS01925
gene id: 48664:PD885_RS01925
uniprot id: A0A1Y6H2C0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

48664:PD885 RS07570
gene id: 48664:PD885_RS07570
uniprot id: A0A1Y6H926
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

48664:PD885 RS19165
gene id: 48664:PD885_RS19165
uniprot id: A0A1Y6HI42
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

48664:PD885 RS13945
gene id: 48664:PD885_RS13945
uniprot id: A0A1Y6H9H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

48664:PD885 RS07850
gene id: 48664:PD885_RS07850
uniprot id: A0A1Y6GV33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

48664:PD885 RS07445
gene id: 48664:PD885_RS07445
uniprot id: A0A1Y6H6H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

48664:PD885 RS15835
gene id: 48664:PD885_RS15835
uniprot id: A0A1Y6HIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS03560
gene id: 48664:PD885_RS03560
uniprot id: A0A1Y6H630
names: Similarity
messages: Belongs to the UPF0234 family.

48664:PD885 RS10370
gene id: 48664:PD885_RS10370
uniprot id: A0A1Y6H733
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

48664:PD885 RS01185
gene id: 48664:PD885_RS01185
uniprot id: A0A1Y6H1V8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

48664:PD885 RS07785
gene id: 48664:PD885_RS07785
uniprot id: A0A1Y6HN47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS19730
gene id: 48664:PD885_RS19730
uniprot id: A0A1Y6HIF7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

48664:PD885 RS03280
gene id: 48664:PD885_RS03280
uniprot id: A0A1Y6HM72
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

48664:PD885 RS08235
gene id: 48664:PD885_RS08235
uniprot id: A0A1Y6HKZ4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS12735
gene id: 48664:PD885_RS12735
uniprot id: A0A1Y6H1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

48664:PD885 RS10995
gene id: 48664:PD885_RS10995
uniprot id: A0A1Y6HIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

48664:PD885 RS01105
gene id: 48664:PD885_RS01105
uniprot id: A0A1Y6H1H7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

48664:PD885 RS08495
gene id: 48664:PD885_RS08495
uniprot id: A0A1Y6HHH9
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

48664:PD885 RS02495
gene id: 48664:PD885_RS02495
uniprot id: A0A1Y6HAI3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS07720
gene id: 48664:PD885_RS07720
uniprot id: A0A1Y6HLV1
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

48664:PD885 RS15890
gene id: 48664:PD885_RS15890
uniprot id: A0A1Y6GZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

48664:PD885 RS08720
gene id: 48664:PD885_RS08720
uniprot id: A0A1Y6H638
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

48664:PD885 RS10360
gene id: 48664:PD885_RS10360
uniprot id: A0A1Y6H818
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

48664:PD885 RS07500
gene id: 48664:PD885_RS07500
uniprot id: A0A1Y6H5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

48664:PD885 RS05530
gene id: 48664:PD885_RS05530
uniprot id: A0A1Y6H760
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

48664:PD885 RS16300
gene id: 48664:PD885_RS16300
uniprot id: A0A1Y6HF66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

48664:PD885 RS18440
gene id: 48664:PD885_RS18440
uniprot id: A0A1Y6HBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

48664:PD885 RS07750
gene id: 48664:PD885_RS07750
uniprot id: A0A1Y6HI20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS16510
gene id: 48664:PD885_RS16510
uniprot id: A0A1Y6HF93
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS17165
gene id: 48664:PD885_RS17165
uniprot id: A0A1Y6HEC7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

48664:PD885 RS09245
gene id: 48664:PD885_RS09245
uniprot id: A0A1Y6HCE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

48664:PD885 RS01290
gene id: 48664:PD885_RS01290
uniprot id: A0A1Y6H1X8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

48664:PD885 RS13790
gene id: 48664:PD885_RS13790
uniprot id: A0A1Y6H8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

48664:PD885 RS00505
gene id: 48664:PD885_RS00505
uniprot id: A0A1Y6HTH1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

48664:PD885 RS13030
gene id: 48664:PD885_RS13030
uniprot id: A0A1Y6HEM4
names: Similarity
messages: Belongs to the GST superfamily.

48664:PD885 RS10645
gene id: 48664:PD885_RS10645
uniprot id: A0A1Y6H768
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

48664:PD885 RS18260
gene id: 48664:PD885_RS18260
uniprot id: A0A1Y6HHA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

48664:PD885 RS13370
gene id: 48664:PD885_RS13370
uniprot id: A0A1Y6HBK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

48664:PD885 RS12175
gene id: 48664:PD885_RS12175
uniprot id: A0A1Y6HE72
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

48664:PD885 RS06190
gene id: 48664:PD885_RS06190
uniprot id: A0A1Y6H0N1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS15415
gene id: 48664:PD885_RS15415
uniprot id: A0A1Y6HFF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS05010
gene id: 48664:PD885_RS05010
uniprot id: A0A1Y6HL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS18805
gene id: 48664:PD885_RS18805
uniprot id: A0A1Y6HI88
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS07890
gene id: 48664:PD885_RS07890
uniprot id: A0A1Y6HN67
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

48664:PD885 RS06745
gene id: 48664:PD885_RS06745
uniprot id: A0A1Y6HK91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

48664:PD885 RS09375
gene id: 48664:PD885_RS09375
uniprot id: A0A1Y6H0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS14630
gene id: 48664:PD885_RS14630
uniprot id: A0A1Y6H140
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

48664:PD885 RS01860
gene id: 48664:PD885_RS01860
uniprot id: A0A1Y6H3E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

48664:PD885 RS05465
gene id: 48664:PD885_RS05465
uniprot id: A0A1Y6HL23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

48664:PD885 RS14575
gene id: 48664:PD885_RS14575
uniprot id: A0A1Y6HFV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

48664:PD885 RS04000
gene id: 48664:PD885_RS04000
uniprot id: A0A1Y6H3F1
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

48664:PD885 RS08635
gene id: 48664:PD885_RS08635
uniprot id: A0A1Y6H611
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

48664:PD885 RS05025
gene id: 48664:PD885_RS05025
uniprot id: A0A1Y6HLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS06610
gene id: 48664:PD885_RS06610
uniprot id: A0A1Y6H9T5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

48664:PD885 RS00255
gene id: 48664:PD885_RS00255
uniprot id: A0A1Y6GT39
names: Similarity
messages: Belongs to the thioredoxin family.

48664:PD885 RS07130
gene id: 48664:PD885_RS07130
uniprot id: A0A1Y6H8U4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS14765
gene id: 48664:PD885_RS14765
uniprot id: A0A1Y6HG81
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

48664:PD885 RS14655
gene id: 48664:PD885_RS14655
uniprot id: A0A1Y6HCB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

48664:PD885 RS07900
gene id: 48664:PD885_RS07900
uniprot id: A0A1Y6HAH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

48664:PD885 RS11340
gene id: 48664:PD885_RS11340
uniprot id: A0A1Y6HMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

48664:PD885 RS07770
gene id: 48664:PD885_RS07770
uniprot id: A0A1Y6GZB0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

48664:PD885 RS01110
gene id: 48664:PD885_RS01110
uniprot id: A0A1Y6H1U7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

48664:PD885 RS00105
gene id: 48664:PD885_RS00105
uniprot id: A0A1Y6H1B4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS19740
gene id: 48664:PD885_RS19740
uniprot id: A0A1Y6HCF2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

48664:PD885 RS12840
gene id: 48664:PD885_RS12840
uniprot id: A0A1Y6H8G8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

48664:PD885 RS05945
gene id: 48664:PD885_RS05945
uniprot id: A0A1Y6GXW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

48664:PD885 RS09810
gene id: 48664:PD885_RS09810
uniprot id: A0A1Y6HBJ7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

48664:PD885 RS14795
gene id: 48664:PD885_RS14795
uniprot id: A0A1Y6HII1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

48664:PD885 RS11050
gene id: 48664:PD885_RS11050
uniprot id: A0A1Y6H7F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

48664:PD885 RS14215
gene id: 48664:PD885_RS14215
uniprot id: A0A1Y6H988
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS12140
gene id: 48664:PD885_RS12140
uniprot id: A0A1Y6H8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

48664:PD885 RS12620
gene id: 48664:PD885_RS12620
uniprot id: A0A1Y6HD64
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

48664:PD885 RS19420
gene id: 48664:PD885_RS19420
uniprot id: A0A1Y6HC69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

48664:PD885 RS12355
gene id: 48664:PD885_RS12355
uniprot id: A0A1Y6HME4
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

48664:PD885 RS00920
gene id: 48664:PD885_RS00920
uniprot id: A0A1Y6HNK2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

48664:PD885 RS14740
gene id: 48664:PD885_RS14740
uniprot id: A0A1Y6HFM1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

48664:PD885 RS14520
gene id: 48664:PD885_RS14520
uniprot id: A0A1Y6HJH0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

48664:PD885 RS00365
gene id: 48664:PD885_RS00365
uniprot id: A0A1Y6HD14
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS18630
gene id: 48664:PD885_RS18630
uniprot id: A0A1Y6HC80
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

48664:PD885 RS12625
gene id: 48664:PD885_RS12625
uniprot id: A0A1Y6HEF2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

48664:PD885 RS10755
gene id: 48664:PD885_RS10755
uniprot id: A0A1Y6GVY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

48664:PD885 RS09600
gene id: 48664:PD885_RS09600
uniprot id: A0A1Y6HI54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS02845
gene id: 48664:PD885_RS02845
uniprot id: A0A1Y6H3Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

48664:PD885 RS05620
gene id: 48664:PD885_RS05620
uniprot id: A0A1Y6GZA0
names: Similarity
messages: Belongs to the citrate synthase family.

48664:PD885 RS13295
gene id: 48664:PD885_RS13295
uniprot id: A0A1Y6HJE0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

48664:PD885 RS00570
gene id: 48664:PD885_RS00570
uniprot id: A0A1Y6H4D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

48664:PD885 RS15245
gene id: 48664:PD885_RS15245
uniprot id: A0A1Y6HGF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

48664:PD885 RS03655
gene id: 48664:PD885_RS03655
uniprot id: A0A1Y6HM03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

48664:PD885 RS12655
gene id: 48664:PD885_RS12655
uniprot id: A0A1Y6GY75
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

48664:PD885 RS03870
gene id: 48664:PD885_RS03870
uniprot id: A0A1Y6H3E7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

48664:PD885 RS03760
gene id: 48664:PD885_RS03760
uniprot id: A0A1Y6GTE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

48664:PD885 RS07725
gene id: 48664:PD885_RS07725
uniprot id: A0A1Y6H953
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

48664:PD885 RS05685
gene id: 48664:PD885_RS05685
uniprot id: A0A1Y6H4B7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

48664:PD885 RS11185
gene id: 48664:PD885_RS11185
uniprot id: A0A1Y6H7I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

48664:PD885 RS13380
gene id: 48664:PD885_RS13380
uniprot id: A0A1Y6H8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

48664:PD885 RS12450
gene id: 48664:PD885_RS12450
uniprot id: A0A1Y6H8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

48664:PD885 RS15725
gene id: 48664:PD885_RS15725
uniprot id: A0A1Y6GYW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

48664:PD885 RS19800
gene id: 48664:PD885_RS19800
uniprot id: A0A1Y6HCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

48664:PD885 RS12460
gene id: 48664:PD885_RS12460
uniprot id: A0A1Y6HB27
names: Similarity
messages: Belongs to the YciI family.

48664:PD885 RS03665
gene id: 48664:PD885_RS03665
uniprot id: A0A1Y6GS17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

48664:PD885 RS15280
gene id: 48664:PD885_RS15280
uniprot id: A0A1Y6H9U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

48664:PD885 RS12930
gene id: 48664:PD885_RS12930
uniprot id: A0A1Y6HEK2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

48664:PD885 RS15905
gene id: 48664:PD885_RS15905
uniprot id: A0A1Y6HB67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

48664:PD885 RS00260
gene id: 48664:PD885_RS00260
uniprot id: A0A1Y6H1E4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS03950
gene id: 48664:PD885_RS03950
uniprot id: A0A1Y6HPN3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

48664:PD885 RS15745
gene id: 48664:PD885_RS15745
uniprot id: A0A1Y6HB39
names: Similarity
messages: Belongs to the Dps family.

48664:PD885 RS14840
gene id: 48664:PD885_RS14840
uniprot id: A0A1Y6HCE9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

48664:PD885 RS02030
gene id: 48664:PD885_RS02030
uniprot id: A0A1Y6GUB9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

48664:PD885 RS09780
gene id: 48664:PD885_RS09780
uniprot id: A0A1Y6H7S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

48664:PD885 RS12585
gene id: 48664:PD885_RS12585
uniprot id: A0A1Y6H8B9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

48664:PD885 RS07040
gene id: 48664:PD885_RS07040
uniprot id: A0A1Y6GX97
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS04060
gene id: 48664:PD885_RS04060
uniprot id: A0A1Y6GYD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS02865
gene id: 48664:PD885_RS02865
uniprot id: A0A1Y6H2V3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

48664:PD885 RS18750
gene id: 48664:PD885_RS18750
uniprot id: A0A1Y6HEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

48664:PD885 RS06845
gene id: 48664:PD885_RS06845
uniprot id: A0A1Y6HK72
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS07365
gene id: 48664:PD885_RS07365
uniprot id: A0A1Y6H8Y9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

48664:PD885 RS07685
gene id: 48664:PD885_RS07685
uniprot id: A0A1Y6HH32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

48664:PD885 RS11730
gene id: 48664:PD885_RS11730
uniprot id: A0A1Y6GWD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

48664:PD885 RS18920
gene id: 48664:PD885_RS18920
uniprot id: A0A1Y6HG48
names: Similarity
messages: Belongs to the DprA/Smf family.

48664:PD885 RS18120
gene id: 48664:PD885_RS18120
uniprot id: A0A1Y6HEB5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

48664:PD885 RS03230
gene id: 48664:PD885_RS03230
uniprot id: A0A1Y6H6Q5
names: Similarity
messages: Belongs to the GARS family.

48664:PD885 RS03635
gene id: 48664:PD885_RS03635
uniprot id: A0A1Y6GX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

48664:PD885 RS01640
gene id: 48664:PD885_RS01640
uniprot id: A0A1Y6HQV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

48664:PD885 RS02970
gene id: 48664:PD885_RS02970
uniprot id: A0A1Y6H2X5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

48664:PD885 RS04845
gene id: 48664:PD885_RS04845
uniprot id: A0A1Y6HM94
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS12345
gene id: 48664:PD885_RS12345
uniprot id: A0A1Y6H8K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

48664:PD885 RS16080
gene id: 48664:PD885_RS16080
uniprot id: A0A1Y6HHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

48664:PD885 RS19855
gene id: 48664:PD885_RS19855
uniprot id: A0A1Y6HDK6
names: Similarity
messages: Belongs to the ParB family.

48664:PD885 RS15840
gene id: 48664:PD885_RS15840
uniprot id: A0A1Y6HA58
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

48664:PD885 RS02735
gene id: 48664:PD885_RS02735
uniprot id: A0A1Y6GRL8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

48664:PD885 RS18915
gene id: 48664:PD885_RS18915
uniprot id: A0A1Y6HEQ7
names: Similarity
messages: Belongs to the Smg family.

48664:PD885 RS16230
gene id: 48664:PD885_RS16230
uniprot id: A0A1Y6HAE3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

48664:PD885 RS05325
gene id: 48664:PD885_RS05325
uniprot id: A0A1Y6H909
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

48664:PD885 RS06835
gene id: 48664:PD885_RS06835
uniprot id: A0A1Y6H530
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

48664:PD885 RS17755
gene id: 48664:PD885_RS17755
uniprot id: A0A1Y6HG34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

48664:PD885 RS02775
gene id: 48664:PD885_RS02775
uniprot id: A0A1Y6GSI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS11160
gene id: 48664:PD885_RS11160
uniprot id: A0A1Y6HB14
names: Similarity
messages: Belongs to the threonine synthase family.

48664:PD885 RS13735
gene id: 48664:PD885_RS13735
uniprot id: A0A1Y6GTJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS06185
gene id: 48664:PD885_RS06185
uniprot id: A0A1Y6HKN0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

48664:PD885 RS08940
gene id: 48664:PD885_RS08940
uniprot id: A0A1Y6H689
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS14530
gene id: 48664:PD885_RS14530
uniprot id: A0A1Y6HAF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

48664:PD885 RS06710
gene id: 48664:PD885_RS06710
uniprot id: A0A1Y6H3C7
names: Similarity
messages: Belongs to the thioredoxin family.

48664:PD885 RS19445
gene id: 48664:PD885_RS19445
uniprot id: A0A1Y6HC82
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

48664:PD885 RS11740
gene id: 48664:PD885_RS11740
uniprot id: A0A1Y6HBD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

48664:PD885 RS19755
gene id: 48664:PD885_RS19755
uniprot id: A0A1Y6HTN2
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS01480
gene id: 48664:PD885_RS01480
uniprot id: A0A1Y6H220
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

48664:PD885 RS07035
gene id: 48664:PD885_RS07035
uniprot id: A0A1Y6H579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

48664:PD885 RS16915
gene id: 48664:PD885_RS16915
uniprot id: A0A1Y6HFG8
names: Similarity
messages: Belongs to the GSP N family.

48664:PD885 RS05100
gene id: 48664:PD885_RS05100
uniprot id: A0A1Y6HS46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

48664:PD885 RS11385
gene id: 48664:PD885_RS11385
uniprot id: A0A1Y6GWY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

48664:PD885 RS11585
gene id: 48664:PD885_RS11585
uniprot id: A0A1Y6GWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

48664:PD885 RS06075
gene id: 48664:PD885_RS06075
uniprot id: A0A1Y6H4M4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

48664:PD885 RS00055
gene id: 48664:PD885_RS00055
uniprot id: A0A1Y6H1A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

48664:PD885 RS01240
gene id: 48664:PD885_RS01240
uniprot id: A0A1Y6H1X3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS04200
gene id: 48664:PD885_RS04200
uniprot id: A0A1Y6HQ83
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS19700
gene id: 48664:PD885_RS19700
uniprot id: A0A1Y6H284
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

48664:PD885 RS09735
gene id: 48664:PD885_RS09735
uniprot id: A0A1Y6GVU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS15070
gene id: 48664:PD885_RS15070
uniprot id: A0A1Y6HCJ9
names: Similarity
messages: Belongs to the histone deacetylase family.

48664:PD885 RS11255
gene id: 48664:PD885_RS11255
uniprot id: A0A1Y6HB36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

48664:PD885 RS08505
gene id: 48664:PD885_RS08505
uniprot id: A0A1Y6H9J2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

48664:PD885 RS07120
gene id: 48664:PD885_RS07120
uniprot id: A0A1Y6H585
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

48664:PD885 RS09785
gene id: 48664:PD885_RS09785
uniprot id: A0A1Y6H751
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

48664:PD885 RS08445
gene id: 48664:PD885_RS08445
uniprot id: A0A1Y6H0M4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

48664:PD885 RS10865
gene id: 48664:PD885_RS10865
uniprot id: A0A1Y6HMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

48664:PD885 RS19395
gene id: 48664:PD885_RS19395
uniprot id: A0A1Y6HC73
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

48664:PD885 RS01690
gene id: 48664:PD885_RS01690
uniprot id: A0A1Y6HN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

48664:PD885 RS04735
gene id: 48664:PD885_RS04735
uniprot id: A0A1Y6H3V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

48664:PD885 RS00245
gene id: 48664:PD885_RS00245
uniprot id: A0A1Y6H483
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

48664:PD885 RS02140
gene id: 48664:PD885_RS02140
uniprot id: A0A1Y6H2G6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

48664:PD885 RS13795
gene id: 48664:PD885_RS13795
uniprot id: A0A1Y6HJW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

48664:PD885 RS13300
gene id: 48664:PD885_RS13300
uniprot id: A0A1Y6H945
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

48664:PD885 RS19365
gene id: 48664:PD885_RS19365
uniprot id: A0A1Y6HD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS05395
gene id: 48664:PD885_RS05395
uniprot id: A0A1Y6H5A2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

48664:PD885 RS14750
gene id: 48664:PD885_RS14750
uniprot id: A0A1Y6HFR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

48664:PD885 RS16425
gene id: 48664:PD885_RS16425
uniprot id: A0A1Y6HAH3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

48664:PD885 RS05895
gene id: 48664:PD885_RS05895
uniprot id: A0A1Y6HAJ6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

48664:PD885 RS01515
gene id: 48664:PD885_RS01515
uniprot id: A0A1Y6H366
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

48664:PD885 RS07700
gene id: 48664:PD885_RS07700
uniprot id: A0A1Y6H5I1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

48664:PD885 RS16225
gene id: 48664:PD885_RS16225
uniprot id: A0A1Y6H2U1
names: Similarity
messages: Belongs to the citrate synthase family.

48664:PD885 RS03400
gene id: 48664:PD885_RS03400
uniprot id: A0A1Y6H9I7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS11190
gene id: 48664:PD885_RS11190
uniprot id: A0A1Y6H7I2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

48664:PD885 RS05125
gene id: 48664:PD885_RS05125
uniprot id: A0A1Y6H444
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS10300
gene id: 48664:PD885_RS10300
uniprot id: A0A1Y6H9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

48664:PD885 RS11260
gene id: 48664:PD885_RS11260
uniprot id: A0A1Y6H006
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

48664:PD885 RS13325
gene id: 48664:PD885_RS13325
uniprot id: A0A1Y6HDI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

48664:PD885 RS13360
gene id: 48664:PD885_RS13360
uniprot id: A0A1Y6H8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

48664:PD885 RS09970
gene id: 48664:PD885_RS09970
uniprot id: A0A1Y6HID2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

48664:PD885 RS14610
gene id: 48664:PD885_RS14610
uniprot id: A0A1Y6GYT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

48664:PD885 RS07450
gene id: 48664:PD885_RS07450
uniprot id: A0A1Y6H5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

48664:PD885 RS18315
gene id: 48664:PD885_RS18315
uniprot id: A0A1Y6HGG9
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS15135
gene id: 48664:PD885_RS15135
uniprot id: A0A1Y6H9R0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

48664:PD885 RS16030
gene id: 48664:PD885_RS16030
uniprot id: A0A1Y6HHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

48664:PD885 RS06475
gene id: 48664:PD885_RS06475
uniprot id: A0A1Y6HKE4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

48664:PD885 RS18935
gene id: 48664:PD885_RS18935
uniprot id: A0A1Y6HBY5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

48664:PD885 RS09720
gene id: 48664:PD885_RS09720
uniprot id: A0A1Y6H6N1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

48664:PD885 RS02710
gene id: 48664:PD885_RS02710
uniprot id: A0A1Y6HMM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

48664:PD885 RS01920
gene id: 48664:PD885_RS01920
uniprot id: A0A1Y6H2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

48664:PD885 RS14900
gene id: 48664:PD885_RS14900
uniprot id: A0A1Y6HAM6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

48664:PD885 RS12475
gene id: 48664:PD885_RS12475
uniprot id: A0A1Y6HKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

48664:PD885 RS04485
gene id: 48664:PD885_RS04485
uniprot id: A0A1Y6H8J1
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

48664:PD885 RS16470
gene id: 48664:PD885_RS16470
uniprot id: A0A1Y6HEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS09385
gene id: 48664:PD885_RS09385
uniprot id: A0A1Y6GZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

48664:PD885 RS17580
gene id: 48664:PD885_RS17580
uniprot id: A0A1Y6HBN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

48664:PD885 RS04900
gene id: 48664:PD885_RS04900
uniprot id: A0A1Y6HLQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

48664:PD885 RS16185
gene id: 48664:PD885_RS16185
uniprot id: A0A1Y6HDW4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS05625
gene id: 48664:PD885_RS05625
uniprot id: A0A1Y6H5E4
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

48664:PD885 RS15345
gene id: 48664:PD885_RS15345
uniprot id: A0A1Y6HAW0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

48664:PD885 RS00685
gene id: 48664:PD885_RS00685
uniprot id: A0A1Y6H4F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

48664:PD885 RS05680
gene id: 48664:PD885_RS05680
uniprot id: A0A1Y6H4E3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

48664:PD885 RS14755
gene id: 48664:PD885_RS14755
uniprot id: A0A1Y6H164
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

48664:PD885 RS00915
gene id: 48664:PD885_RS00915
uniprot id: A0A1Y6H1R8
names: Similarity
messages: Belongs to the glutamine synthetase family.

48664:PD885 RS12155
gene id: 48664:PD885_RS12155
uniprot id: A0A1Y6HBM3
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

48664:PD885 RS08750
gene id: 48664:PD885_RS08750
uniprot id: A0A1Y6HKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS06115
gene id: 48664:PD885_RS06115
uniprot id: A0A1Y6HL25
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

48664:PD885 RS17270
gene id: 48664:PD885_RS17270
uniprot id: A0A1Y6HBH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

48664:PD885 RS13210
gene id: 48664:PD885_RS13210
uniprot id: A0A1Y6H8P8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

48664:PD885 RS10650
gene id: 48664:PD885_RS10650
uniprot id: A0A1Y6HJN6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

48664:PD885 RS16585
gene id: 48664:PD885_RS16585
uniprot id: A0A1Y6HAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

48664:PD885 RS01100
gene id: 48664:PD885_RS01100
uniprot id: A0A1Y6HPJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS05170
gene id: 48664:PD885_RS05170
uniprot id: A0A1Y6H451
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

48664:PD885 RS00035
gene id: 48664:PD885_RS00035
uniprot id: A0A1Y6HHM3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

48664:PD885 RS11000
gene id: 48664:PD885_RS11000
uniprot id: A0A1Y6H7E6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

48664:PD885 RS06730
gene id: 48664:PD885_RS06730
uniprot id: A0A1Y6HB12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

48664:PD885 RS06670
gene id: 48664:PD885_RS06670
uniprot id: A0A1Y6H4Z7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

48664:PD885 RS05180
gene id: 48664:PD885_RS05180
uniprot id: A0A1Y6H561
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

48664:PD885 RS08965
gene id: 48664:PD885_RS08965
uniprot id: A0A1Y6GW34
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

48664:PD885 RS08895
gene id: 48664:PD885_RS08895
uniprot id: A0A1Y6H664
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

48664:PD885 RS09990
gene id: 48664:PD885_RS09990
uniprot id: A0A1Y6H791
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

48664:PD885 RS01870
gene id: 48664:PD885_RS01870
uniprot id: A0A1Y6H2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

48664:PD885 RS14860
gene id: 48664:PD885_RS14860
uniprot id: A0A1Y6HA16
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

48664:PD885 RS01695
gene id: 48664:PD885_RS01695
uniprot id: A0A1Y6H259
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS16130
gene id: 48664:PD885_RS16130
uniprot id: A0A1Y6HHR2
names: Similarity
messages: Belongs to the CcdB toxin family.

48664:PD885 RS12340
gene id: 48664:PD885_RS12340
uniprot id: A0A1Y6H972
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

48664:PD885 RS14595
gene id: 48664:PD885_RS14595
uniprot id: A0A1Y6GYB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

48664:PD885 RS08550
gene id: 48664:PD885_RS08550
uniprot id: A0A1Y6H5Z0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

48664:PD885 RS15670
gene id: 48664:PD885_RS15670
uniprot id: A0A1Y6GYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

48664:PD885 RS10740
gene id: 48664:PD885_RS10740
uniprot id: A0A1Y6HIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

48664:PD885 RS10875
gene id: 48664:PD885_RS10875
uniprot id: A0A1Y6HNN0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

48664:PD885 RS17170
gene id: 48664:PD885_RS17170
uniprot id: A0A1Y6HBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

48664:PD885 RS04260
gene id: 48664:PD885_RS04260
uniprot id: A0A1Y6HM36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

48664:PD885 RS11480
gene id: 48664:PD885_RS11480
uniprot id: A0A1Y6H835
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

48664:PD885 RS14100
gene id: 48664:PD885_RS14100
uniprot id: A0A1Y6HJQ1
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS09300
gene id: 48664:PD885_RS09300
uniprot id: A0A1Y6HIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

48664:PD885 RS01250
gene id: 48664:PD885_RS01250
uniprot id: A0A1Y6HNT6
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS06955
gene id: 48664:PD885_RS06955
uniprot id: A0A1Y6H552
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

48664:PD885 RS05050
gene id: 48664:PD885_RS05050
uniprot id: A0A1Y6GTM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS14820
gene id: 48664:PD885_RS14820
uniprot id: A0A1Y6HA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS10710
gene id: 48664:PD885_RS10710
uniprot id: A0A1Y6GVZ2
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

48664:PD885 RS12115
gene id: 48664:PD885_RS12115
uniprot id: A0A1Y6HCX1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS09955
gene id: 48664:PD885_RS09955
uniprot id: A0A1Y6HAC1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

48664:PD885 RS19375
gene id: 48664:PD885_RS19375
uniprot id: A0A1Y6HHX8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

48664:PD885 RS01845
gene id: 48664:PD885_RS01845
uniprot id: A0A1Y6H874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

48664:PD885 RS08640
gene id: 48664:PD885_RS08640
uniprot id: A0A1Y6H9M2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

48664:PD885 RS13610
gene id: 48664:PD885_RS13610
uniprot id: A0A1Y6H8X3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

48664:PD885 RS11040
gene id: 48664:PD885_RS11040
uniprot id: A0A1Y6GYW2
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

48664:PD885 RS04865
gene id: 48664:PD885_RS04865
uniprot id: A0A1Y6H403
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

48664:PD885 RS04610
gene id: 48664:PD885_RS04610
uniprot id: A0A1Y6H8M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

48664:PD885 RS02480
gene id: 48664:PD885_RS02480
uniprot id: A0A1Y6H8L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

48664:PD885 RS01475
gene id: 48664:PD885_RS01475
uniprot id: A0A1Y6H2J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

48664:PD885 RS03985
gene id: 48664:PD885_RS03985
uniprot id: A0A1Y6H895
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

48664:PD885 RS17485
gene id: 48664:PD885_RS17485
uniprot id: A0A1Y6GXX9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

48664:PD885 RS09390
gene id: 48664:PD885_RS09390
uniprot id: A0A1Y6GVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

48664:PD885 RS06010
gene id: 48664:PD885_RS06010
uniprot id: A0A1Y6H5N3
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

48664:PD885 RS18815
gene id: 48664:PD885_RS18815
uniprot id: A0A1Y6HH04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

48664:PD885 RS08065
gene id: 48664:PD885_RS08065
uniprot id: A0A1Y6HBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

48664:PD885 RS06655
gene id: 48664:PD885_RS06655
uniprot id: A0A1Y6H7T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

48664:PD885 RS00075
gene id: 48664:PD885_RS00075
uniprot id: A0A1Y6H1A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS07015
gene id: 48664:PD885_RS07015
uniprot id: A0A1Y6GXB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS16430
gene id: 48664:PD885_RS16430
uniprot id: A0A1Y6HAH6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

48664:PD885 RS08450
gene id: 48664:PD885_RS08450
uniprot id: A0A1Y6HHG9
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

48664:PD885 RS07610
gene id: 48664:PD885_RS07610
uniprot id: A0A1Y6H5G2
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS09020
gene id: 48664:PD885_RS09020
uniprot id: A0A1Y6HB38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS11430
gene id: 48664:PD885_RS11430
uniprot id: A0A1Y6H820
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

48664:PD885 RS01450
gene id: 48664:PD885_RS01450
uniprot id: A0A1Y6HPC1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

48664:PD885 RS13310
gene id: 48664:PD885_RS13310
uniprot id: A0A1Y6H8R7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS15485
gene id: 48664:PD885_RS15485
uniprot id: A0A1Y6HIW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

48664:PD885 RS16830
gene id: 48664:PD885_RS16830
uniprot id: A0A1Y6HBS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

48664:PD885 RS06785
gene id: 48664:PD885_RS06785
uniprot id: A0A1Y6HQ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

48664:PD885 RS14845
gene id: 48664:PD885_RS14845
uniprot id: A0A1Y6HEC0
names: Similarity
messages: Belongs to the peptidase S8 family.

48664:PD885 RS06040
gene id: 48664:PD885_RS06040
uniprot id: A0A1Y6HRM0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

48664:PD885 RS12125
gene id: 48664:PD885_RS12125
uniprot id: A0A1Y6HK11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

48664:PD885 RS16855
gene id: 48664:PD885_RS16855
uniprot id: A0A1Y6HDL5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

48664:PD885 RS12635
gene id: 48664:PD885_RS12635
uniprot id: A0A1Y6HK97
names: Similarity
messages: Belongs to the barstar family.

48664:PD885 RS10890
gene id: 48664:PD885_RS10890
uniprot id: A0A1Y6H7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

48664:PD885 RS08475
gene id: 48664:PD885_RS08475
uniprot id: A0A1Y6HHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

48664:PD885 RS18095
gene id: 48664:PD885_RS18095
uniprot id: A0A1Y6HCJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS18900
gene id: 48664:PD885_RS18900
uniprot id: A0A1Y6HBX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

48664:PD885 RS17705
gene id: 48664:PD885_RS17705
uniprot id: A0A1Y6HE60
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

48664:PD885 RS12910
gene id: 48664:PD885_RS12910
uniprot id: A0A1Y6H8I2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS14600
gene id: 48664:PD885_RS14600
uniprot id: A0A1Y6HFW2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

48664:PD885 RS07825
gene id: 48664:PD885_RS07825
uniprot id: A0A1Y6HKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

48664:PD885 RS13245
gene id: 48664:PD885_RS13245
uniprot id: A0A1Y6HJF0
names: Similarity
messages: Belongs to the ArsC family.

48664:PD885 RS14675
gene id: 48664:PD885_RS14675
uniprot id: A0A1Y6H9I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

48664:PD885 RS06415
gene id: 48664:PD885_RS06415
uniprot id: A0A1Y6H5W8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

48664:PD885 RS09740
gene id: 48664:PD885_RS09740
uniprot id: A0A1Y6H1P4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

48664:PD885 RS18385
gene id: 48664:PD885_RS18385
uniprot id: A0A1Y6HDN8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

48664:PD885 RS03450
gene id: 48664:PD885_RS03450
uniprot id: A0A1Y6GY09
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

48664:PD885 RS15720
gene id: 48664:PD885_RS15720
uniprot id: A0A1Y6HEU5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

48664:PD885 RS05890
gene id: 48664:PD885_RS05890
uniprot id: A0A1Y6H9C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

48664:PD885 RS12610
gene id: 48664:PD885_RS12610
uniprot id: A0A1Y6HBW2
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

48664:PD885 RS19000
gene id: 48664:PD885_RS19000
uniprot id: A0A1Y6HED2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

48664:PD885 RS02245
gene id: 48664:PD885_RS02245
uniprot id: A0A1Y6H2I1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS12330
gene id: 48664:PD885_RS12330
uniprot id: A0A1Y6H869
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

48664:PD885 RS06095
gene id: 48664:PD885_RS06095
uniprot id: A0A1Y6H4M7
names: Similarity
messages: Belongs to the GSP E family.

48664:PD885 RS06995
gene id: 48664:PD885_RS06995
uniprot id: A0A1Y6H691
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

48664:PD885 RS04705
gene id: 48664:PD885_RS04705
uniprot id: A0A1Y6GSN7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

48664:PD885 RS19720
gene id: 48664:PD885_RS19720
uniprot id: A0A1Y6HQ05
names: Similarity
messages: Belongs to the MlaA family.

48664:PD885 RS06460
gene id: 48664:PD885_RS06460
uniprot id: A0A1Y6H4V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

48664:PD885 RS00990
gene id: 48664:PD885_RS00990
uniprot id: A0A1Y6H5E8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

48664:PD885 RS15690
gene id: 48664:PD885_RS15690
uniprot id: A0A1Y6HAI4
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

48664:PD885 RS18540
gene id: 48664:PD885_RS18540
uniprot id: A0A1Y6GQE1
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

48664:PD885 RS19610
gene id: 48664:PD885_RS19610
uniprot id: A0A1Y6HUK2
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS01075
gene id: 48664:PD885_RS01075
uniprot id: A0A1Y6H2V7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

48664:PD885 RS15475
gene id: 48664:PD885_RS15475
uniprot id: A0A1Y6HK55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS01485
gene id: 48664:PD885_RS01485
uniprot id: A0A1Y6H5Q5
names: Similarity
messages: Belongs to the glutamine synthetase family.

48664:PD885 RS07755
gene id: 48664:PD885_RS07755
uniprot id: A0A1Y6HHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS10855
gene id: 48664:PD885_RS10855
uniprot id: A0A1Y6HIW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

48664:PD885 RS13385
gene id: 48664:PD885_RS13385
uniprot id: A0A1Y6H8S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

48664:PD885 RS09265
gene id: 48664:PD885_RS09265
uniprot id: A0A1Y6H6T9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

48664:PD885 RS03970
gene id: 48664:PD885_RS03970
uniprot id: A0A1Y6H3G6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

48664:PD885 RS09155
gene id: 48664:PD885_RS09155
uniprot id: A0A1Y6H6B0
names: Similarity
messages: Belongs to the peptidase S8 family.

48664:PD885 RS08960
gene id: 48664:PD885_RS08960
uniprot id: A0A1Y6H934
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

48664:PD885 RS07020
gene id: 48664:PD885_RS07020
uniprot id: A0A1Y6H367
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

48664:PD885 RS05715
gene id: 48664:PD885_RS05715
uniprot id: A0A1Y6H785
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

48664:PD885 RS04150
gene id: 48664:PD885_RS04150
uniprot id: A0A1Y6HQ94
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

48664:PD885 RS12890
gene id: 48664:PD885_RS12890
uniprot id: A0A1Y6GU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

48664:PD885 RS08250
gene id: 48664:PD885_RS08250
uniprot id: A0A1Y6HND9
names: Function
names: Similarity
messages: Belongs to the GSP E family.
messages: Part of the Type IV secretion system.

48664:PD885 RS15885
gene id: 48664:PD885_RS15885
uniprot id: A0A1Y6HEY3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

48664:PD885 RS09350
gene id: 48664:PD885_RS09350
uniprot id: A0A1Y6GWN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.

48664:PD885 RS17080
gene id: 48664:PD885_RS17080
uniprot id: A0A1Y6HH59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

48664:PD885 RS04545
gene id: 48664:PD885_RS04545
uniprot id: A0A1Y6H4A1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

48664:PD885 RS14440
gene id: 48664:PD885_RS14440
uniprot id: A0A1Y6HCV6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

48664:PD885 RS01335
gene id: 48664:PD885_RS01335
uniprot id: A0A1Y6H1Y9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

48664:PD885 RS09065
gene id: 48664:PD885_RS09065
uniprot id: A0A1Y6HNU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

48664:PD885 RS18840
gene id: 48664:PD885_RS18840
uniprot id: A0A1Y6HBV7
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

48664:PD885 RS17420
gene id: 48664:PD885_RS17420
uniprot id: A0A1Y6GRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

48664:PD885 RS03020
gene id: 48664:PD885_RS03020
uniprot id: A0A1Y6GSB5
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS14040
gene id: 48664:PD885_RS14040
uniprot id: A0A1Y6HKY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

48664:PD885 RS01855
gene id: 48664:PD885_RS01855
uniprot id: A0A1Y6H2A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

48664:PD885 RS15105
gene id: 48664:PD885_RS15105
uniprot id: A0A1Y6H9T2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

48664:PD885 RS17430
gene id: 48664:PD885_RS17430
uniprot id: A0A1Y6HK82
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

48664:PD885 RS08890
gene id: 48664:PD885_RS08890
uniprot id: A0A1Y6H679
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

48664:PD885 RS16945
gene id: 48664:PD885_RS16945
uniprot id: A0A1Y6HDN0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

48664:PD885 RS05110
gene id: 48664:PD885_RS05110
uniprot id: A0A1Y6HNY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

48664:PD885 RS16245
gene id: 48664:PD885_RS16245
uniprot id: A0A1Y6HF54
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

48664:PD885 RS03265
gene id: 48664:PD885_RS03265
uniprot id: A0A1Y6H3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

48664:PD885 RS10840
gene id: 48664:PD885_RS10840
uniprot id: A0A1Y6GV71
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

48664:PD885 RS07810
gene id: 48664:PD885_RS07810
uniprot id: A0A1Y6H6P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS14745
gene id: 48664:PD885_RS14745
uniprot id: A0A1Y6HJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

48664:PD885 RS08900
gene id: 48664:PD885_RS08900
uniprot id: A0A1Y6H9S2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS05790
gene id: 48664:PD885_RS05790
uniprot id: A0A1Y6HLS8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

48664:PD885 RS12955
gene id: 48664:PD885_RS12955
uniprot id: A0A1Y6GX00
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

48664:PD885 RS00965
gene id: 48664:PD885_RS00965
uniprot id: A0A1Y6H1S8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

48664:PD885 RS14580
gene id: 48664:PD885_RS14580
uniprot id: A0A1Y6HAH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

48664:PD885 RS19830
gene id: 48664:PD885_RS19830
uniprot id: A0A1Y6H605
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

48664:PD885 RS12470
gene id: 48664:PD885_RS12470
uniprot id: A0A1Y6GZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

48664:PD885 RS00510
gene id: 48664:PD885_RS00510
uniprot id: A0A1Y6GW71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

48664:PD885 RS11045
gene id: 48664:PD885_RS11045
uniprot id: A0A1Y6HIY9
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

48664:PD885 RS08105
gene id: 48664:PD885_RS08105
uniprot id: A0A1Y6HBT7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

48664:PD885 RS06965
gene id: 48664:PD885_RS06965
uniprot id: A0A1Y6HK71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

48664:PD885 RS09075
gene id: 48664:PD885_RS09075
uniprot id: A0A1Y6HCB9
names: Similarity
messages: Belongs to the SCO1/2 family.

48664:PD885 RS04435
gene id: 48664:PD885_RS04435
uniprot id: A0A1Y6H6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS12725
gene id: 48664:PD885_RS12725
uniprot id: A0A1Y6HEG4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

48664:PD885 RS18735
gene id: 48664:PD885_RS18735
uniprot id: A0A1Y6HBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

48664:PD885 RS18740
gene id: 48664:PD885_RS18740
uniprot id: A0A1Y6HDI1
names: Similarity
messages: Belongs to the Gfa family.

48664:PD885 RS19820
gene id: 48664:PD885_RS19820
uniprot id: A0A1Y6HCF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

48664:PD885 RS01395
gene id: 48664:PD885_RS01395
uniprot id: A0A1Y6H0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS09070
gene id: 48664:PD885_RS09070
uniprot id: A0A1Y6HB49
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

48664:PD885 RS10295
gene id: 48664:PD885_RS10295
uniprot id: A0A1Y6HIY8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

48664:PD885 RS15715
gene id: 48664:PD885_RS15715
uniprot id: A0A1Y6HCW7
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

48664:PD885 RS10265
gene id: 48664:PD885_RS10265
uniprot id: A0A1Y6H6Z4
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

48664:PD885 RS02150
gene id: 48664:PD885_RS02150
uniprot id: A0A1Y6H3L4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS11605
gene id: 48664:PD885_RS11605
uniprot id: A0A1Y6H7S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

48664:PD885 RS05615
gene id: 48664:PD885_RS05615
uniprot id: A0A1Y6GYN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

48664:PD885 RS04960
gene id: 48664:PD885_RS04960
uniprot id: A0A1Y6GVV7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

48664:PD885 RS14685
gene id: 48664:PD885_RS14685
uniprot id: A0A1Y6HG92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

48664:PD885 RS12145
gene id: 48664:PD885_RS12145
uniprot id: A0A1Y6H0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

48664:PD885 RS10895
gene id: 48664:PD885_RS10895
uniprot id: A0A1Y6GV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

48664:PD885 RS00010
gene id: 48664:PD885_RS00010
uniprot id: A0A1Y6GR81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

48664:PD885 RS08100
gene id: 48664:PD885_RS08100
uniprot id: A0A1Y6HAL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

48664:PD885 RS14435
gene id: 48664:PD885_RS14435
uniprot id: A0A1Y6H9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

48664:PD885 RS08075
gene id: 48664:PD885_RS08075
uniprot id: A0A1Y6GXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

48664:PD885 RS10860
gene id: 48664:PD885_RS10860
uniprot id: A0A1Y6HIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

48664:PD885 RS16550
gene id: 48664:PD885_RS16550
uniprot id: A0A1Y6GZE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

48664:PD885 RS00190
gene id: 48664:PD885_RS00190
uniprot id: A0A1Y6H474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

48664:PD885 RS15140
gene id: 48664:PD885_RS15140
uniprot id: A0A1Y6HFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

48664:PD885 RS17425
gene id: 48664:PD885_RS17425
uniprot id: A0A1Y6HE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

48664:PD885 RS01275
gene id: 48664:PD885_RS01275
uniprot id: A0A1Y6H370
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS03365
gene id: 48664:PD885_RS03365
uniprot id: A0A1Y6GRV5
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

48664:PD885 RS14950
gene id: 48664:PD885_RS14950
uniprot id: A0A1Y6GYF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

48664:PD885 RS04715
gene id: 48664:PD885_RS04715
uniprot id: A0A1Y6H3V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

48664:PD885 RS10820
gene id: 48664:PD885_RS10820
uniprot id: A0A1Y6H168
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

48664:PD885 RS18930
gene id: 48664:PD885_RS18930
uniprot id: A0A1Y6HDB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

48664:PD885 RS00750
gene id: 48664:PD885_RS00750
uniprot id: A0A1Y6GRL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

48664:PD885 RS07340
gene id: 48664:PD885_RS07340
uniprot id: A0A1Y6H5B0
names: Similarity
messages: Belongs to the CFA/CMAS family.

48664:PD885 RS12630
gene id: 48664:PD885_RS12630
uniprot id: A0A1Y6H8C5
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

48664:PD885 RS00435
gene id: 48664:PD885_RS00435
uniprot id: A0A1Y6HD23
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

48664:PD885 RS19335
gene id: 48664:PD885_RS19335
uniprot id: A0A1Y6HFR1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS03105
gene id: 48664:PD885_RS03105
uniprot id: A0A1Y6HQ14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS18230
gene id: 48664:PD885_RS18230
uniprot id: A0A1Y6HHL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

48664:PD885 RS09295
gene id: 48664:PD885_RS09295
uniprot id: A0A1Y6HI07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

48664:PD885 RS01215
gene id: 48664:PD885_RS01215
uniprot id: A0A1Y6H1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

48664:PD885 RS16975
gene id: 48664:PD885_RS16975
uniprot id: A0A1Y6HBB1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

48664:PD885 RS01600
gene id: 48664:PD885_RS01600
uniprot id: A0A1Y6HNB0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

48664:PD885 RS13680
gene id: 48664:PD885_RS13680
uniprot id: A0A1Y6HF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

48664:PD885 RS07580
gene id: 48664:PD885_RS07580
uniprot id: A0A1Y6H8B5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS05360
gene id: 48664:PD885_RS05360
uniprot id: A0A1Y6HL37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

48664:PD885 RS03955
gene id: 48664:PD885_RS03955
uniprot id: A0A1Y6H4J3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

48664:PD885 RS16050
gene id: 48664:PD885_RS16050
uniprot id: A0A1Y6HFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

48664:PD885 RS05540
gene id: 48664:PD885_RS05540
uniprot id: A0A1Y6HAC5
names: Similarity
messages: Belongs to the fabD family.

48664:PD885 RS09165
gene id: 48664:PD885_RS09165
uniprot id: A0A1Y6HNW5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

48664:PD885 RS14615
gene id: 48664:PD885_RS14615
uniprot id: A0A1Y6GY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

48664:PD885 RS02555
gene id: 48664:PD885_RS02555
uniprot id: A0A1Y6HSD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

48664:PD885 RS13705
gene id: 48664:PD885_RS13705
uniprot id: A0A1Y6H9C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

48664:PD885 RS16745
gene id: 48664:PD885_RS16745
uniprot id: A0A1Y6H4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

48664:PD885 RS07355
gene id: 48664:PD885_RS07355
uniprot id: A0A1Y6H5B4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS03680
gene id: 48664:PD885_RS03680
uniprot id: A0A1Y6GV48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

48664:PD885 RS07135
gene id: 48664:PD885_RS07135
uniprot id: A0A1Y6H838
names: Similarity
messages: Belongs to the peptidase M13 family.

48664:PD885 RS04680
gene id: 48664:PD885_RS04680
uniprot id: A0A1Y6HLG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

48664:PD885 RS03930
gene id: 48664:PD885_RS03930
uniprot id: A0A1Y6H6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

48664:PD885 RS10730
gene id: 48664:PD885_RS10730
uniprot id: A0A1Y6H092
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

48664:PD885 RS09205
gene id: 48664:PD885_RS09205
uniprot id: A0A1Y6H7F7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

48664:PD885 RS10830
gene id: 48664:PD885_RS10830
uniprot id: A0A1Y6GY53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

48664:PD885 RS06335
gene id: 48664:PD885_RS06335
uniprot id: A0A1Y6HKX6
names: Similarity
messages: Belongs to the Fur family.

48664:PD885 RS04720
gene id: 48664:PD885_RS04720
uniprot id: A0A1Y6GSN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

48664:PD885 RS06915
gene id: 48664:PD885_RS06915
uniprot id: A0A1Y6H539
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

48664:PD885 RS01270
gene id: 48664:PD885_RS01270
uniprot id: A0A1Y6HU61
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

48664:PD885 RS13375
gene id: 48664:PD885_RS13375
uniprot id: A0A1Y6HEU3
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS09380
gene id: 48664:PD885_RS09380
uniprot id: A0A1Y6GYX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

48664:PD885 RS08950
gene id: 48664:PD885_RS08950
uniprot id: A0A1Y6H0X7
names: Similarity
messages: Belongs to the HesB/IscA family.

48664:PD885 RS12535
gene id: 48664:PD885_RS12535
uniprot id: A0A1Y6HK80
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

48664:PD885 RS01190
gene id: 48664:PD885_RS01190
uniprot id: A0A1Y6H1W1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS14965
gene id: 48664:PD885_RS14965
uniprot id: A0A1Y6H393
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

48664:PD885 RS03700
gene id: 48664:PD885_RS03700
uniprot id: A0A1Y6H6Y0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS02625
gene id: 48664:PD885_RS02625
uniprot id: A0A1Y6H5L6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

48664:PD885 RS11410
gene id: 48664:PD885_RS11410
uniprot id: A0A1Y6HDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

48664:PD885 RS00910
gene id: 48664:PD885_RS00910
uniprot id: A0A1Y6GR56
names: Similarity
messages: Belongs to the P(II) protein family.

48664:PD885 RS15230
gene id: 48664:PD885_RS15230
uniprot id: A0A1Y6H9U2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

48664:PD885 RS14770
gene id: 48664:PD885_RS14770
uniprot id: A0A1Y6H9L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

48664:PD885 RS12510
gene id: 48664:PD885_RS12510
uniprot id: A0A1Y6HB37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS17120
gene id: 48664:PD885_RS17120
uniprot id: A0A1Y6HBE3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

48664:PD885 RS05780
gene id: 48664:PD885_RS05780
uniprot id: A0A1Y6H4Y6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

48664:PD885 RS05595
gene id: 48664:PD885_RS05595
uniprot id: A0A1Y6H770
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS16515
gene id: 48664:PD885_RS16515
uniprot id: A0A1Y6HAJ9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

48664:PD885 RS18040
gene id: 48664:PD885_RS18040
uniprot id: A0A1Y6HBF1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS05555
gene id: 48664:PD885_RS05555
uniprot id: A0A1Y6H5D4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

48664:PD885 RS14625
gene id: 48664:PD885_RS14625
uniprot id: A0A1Y6HFU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

48664:PD885 RS08910
gene id: 48664:PD885_RS08910
uniprot id: A0A1Y6GW23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

48664:PD885 RS04675
gene id: 48664:PD885_RS04675
uniprot id: A0A1Y6HLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

48664:PD885 RS03660
gene id: 48664:PD885_RS03660
uniprot id: A0A1Y6H833
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

48664:PD885 RS15965
gene id: 48664:PD885_RS15965
uniprot id: A0A1Y6HAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

48664:PD885 RS05550
gene id: 48664:PD885_RS05550
uniprot id: A0A1Y6H499
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

48664:PD885 RS14560
gene id: 48664:PD885_RS14560
uniprot id: A0A1Y6HE66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

48664:PD885 RS02790
gene id: 48664:PD885_RS02790
uniprot id: A0A1Y6H2T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

48664:PD885 RS15505
gene id: 48664:PD885_RS15505
uniprot id: A0A1Y6HFD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

48664:PD885 RS17345
gene id: 48664:PD885_RS17345
uniprot id: A0A1Y6HDW5
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS01465
gene id: 48664:PD885_RS01465
uniprot id: A0A1Y6H226
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

48664:PD885 RS07225
gene id: 48664:PD885_RS07225
uniprot id: A0A1Y6GX75
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

48664:PD885 RS17845
gene id: 48664:PD885_RS17845
uniprot id: A0A1Y6HHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

48664:PD885 RS03975
gene id: 48664:PD885_RS03975
uniprot id: A0A1Y6H723
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

48664:PD885 RS15080
gene id: 48664:PD885_RS15080
uniprot id: A0A1Y6HFT9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

48664:PD885 RS07845
gene id: 48664:PD885_RS07845
uniprot id: A0A1Y6GVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

48664:PD885 RS18765
gene id: 48664:PD885_RS18765
uniprot id: A0A1Y6HH12
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

48664:PD885 RS14935
gene id: 48664:PD885_RS14935
uniprot id: A0A1Y6HED8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

48664:PD885 RS15145
gene id: 48664:PD885_RS15145
uniprot id: A0A1Y6HAS7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

48664:PD885 RS07320
gene id: 48664:PD885_RS07320
uniprot id: A0A1Y6H8X6
names: Similarity
messages: Belongs to the RutC family.

48664:PD885 RS19955
gene id: 48664:PD885_RS19955
uniprot id: A0A1Y6HRT0
names: Function
names: Similarity
messages: Belongs to the GSP E family.
messages: Part of the Type IV secretion system.

48664:PD885 RS05520
gene id: 48664:PD885_RS05520
uniprot id: A0A1Y6GT41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

48664:PD885 RS02420
gene id: 48664:PD885_RS02420
uniprot id: A0A1Y6GRG1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS14635
gene id: 48664:PD885_RS14635
uniprot id: A0A1Y6HGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

48664:PD885 RS02170
gene id: 48664:PD885_RS02170
uniprot id: A0A1Y6H5C7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

48664:PD885 RS15520
gene id: 48664:PD885_RS15520
uniprot id: A0A1Y6HG26
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS01165
gene id: 48664:PD885_RS01165
uniprot id: A0A1Y6H1W5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

48664:PD885 RS17410
gene id: 48664:PD885_RS17410
uniprot id: A0A1Y6HH55
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

48664:PD885 RS16285
gene id: 48664:PD885_RS16285
uniprot id: A0A1Y6HDY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

48664:PD885 RS12915
gene id: 48664:PD885_RS12915
uniprot id: A0A1Y6HGX5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS17685
gene id: 48664:PD885_RS17685
uniprot id: A0A1Y6HGT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS12440
gene id: 48664:PD885_RS12440
uniprot id: A0A1Y6HJT4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS14605
gene id: 48664:PD885_RS14605
uniprot id: A0A1Y6HCA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

48664:PD885 RS16740
gene id: 48664:PD885_RS16740
uniprot id: A0A1Y6HEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

48664:PD885 RS07655
gene id: 48664:PD885_RS07655
uniprot id: A0A1Y6HH35
names: Similarity
messages: Belongs to the TrpF family.

48664:PD885 RS12520
gene id: 48664:PD885_RS12520
uniprot id: A0A1Y6HED7
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS17635
gene id: 48664:PD885_RS17635
uniprot id: A0A1Y6HIX8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

48664:PD885 RS03030
gene id: 48664:PD885_RS03030
uniprot id: A0A1Y6H3F8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

48664:PD885 RS02300
gene id: 48664:PD885_RS02300
uniprot id: A0A1Y6H7D5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

48664:PD885 RS13240
gene id: 48664:PD885_RS13240
uniprot id: A0A1Y6H8P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

48664:PD885 RS10745
gene id: 48664:PD885_RS10745
uniprot id: A0A1Y6HIU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

48664:PD885 RS09840
gene id: 48664:PD885_RS09840
uniprot id: A0A1Y6H6S5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

48664:PD885 RS14640
gene id: 48664:PD885_RS14640
uniprot id: A0A1Y6H9J0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

48664:PD885 RS06150
gene id: 48664:PD885_RS06150
uniprot id: A0A1Y6H5Q9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

48664:PD885 RS05090
gene id: 48664:PD885_RS05090
uniprot id: A0A1Y6H8W6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

48664:PD885 RS01325
gene id: 48664:PD885_RS01325
uniprot id: A0A1Y6H360
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS06125
gene id: 48664:PD885_RS06125
uniprot id: A0A1Y6H3N7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

48664:PD885 RS14780
gene id: 48664:PD885_RS14780
uniprot id: A0A1Y6HD22
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

48664:PD885 RS15120
gene id: 48664:PD885_RS15120
uniprot id: A0A1Y6HCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

48664:PD885 RS05420
gene id: 48664:PD885_RS05420
uniprot id: A0A1Y6H7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS13175
gene id: 48664:PD885_RS13175
uniprot id: A0A1Y6HGQ2
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS11600
gene id: 48664:PD885_RS11600
uniprot id: A0A1Y6HM04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

48664:PD885 RS05835
gene id: 48664:PD885_RS05835
uniprot id: A0A1Y6H7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

48664:PD885 RS06140
gene id: 48664:PD885_RS06140
uniprot id: A0A1Y6H4N7
names: Similarity
messages: Belongs to the PhzF family.

48664:PD885 RS01380
gene id: 48664:PD885_RS01380
uniprot id: A0A1Y6H2H1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS16545
gene id: 48664:PD885_RS16545
uniprot id: A0A1Y6HIA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS03835
gene id: 48664:PD885_RS03835
uniprot id: A0A1Y6H9C2
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

48664:PD885 RS08975
gene id: 48664:PD885_RS08975
uniprot id: A0A1Y6GUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

48664:PD885 RS08455
gene id: 48664:PD885_RS08455
uniprot id: A0A1Y6H5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

48664:PD885 RS09830
gene id: 48664:PD885_RS09830
uniprot id: A0A1Y6H7T2
names: Similarity
messages: Belongs to the elongation factor P family.

48664:PD885 RS13450
gene id: 48664:PD885_RS13450
uniprot id: A0A1Y6HBM6
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

48664:PD885 RS13330
gene id: 48664:PD885_RS13330
uniprot id: A0A1Y6HET4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS07680
gene id: 48664:PD885_RS07680
uniprot id: A0A1Y6H942
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

48664:PD885 RS03750
gene id: 48664:PD885_RS03750
uniprot id: A0A1Y6GS50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

48664:PD885 RS05705
gene id: 48664:PD885_RS05705
uniprot id: A0A1Y6H4E4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

48664:PD885 RS04510
gene id: 48664:PD885_RS04510
uniprot id: A0A1Y6H3P7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS09555
gene id: 48664:PD885_RS09555
uniprot id: A0A1Y6H6Z2
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS09730
gene id: 48664:PD885_RS09730
uniprot id: A0A1Y6H7R3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

48664:PD885 RS14785
gene id: 48664:PD885_RS14785
uniprot id: A0A1Y6HLR2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

48664:PD885 RS12805
gene id: 48664:PD885_RS12805
uniprot id: A0A1Y6H8U7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

48664:PD885 RS13550
gene id: 48664:PD885_RS13550
uniprot id: A0A1Y6HDN7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

48664:PD885 RS12650
gene id: 48664:PD885_RS12650
uniprot id: A0A1Y6GWV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS19315
gene id: 48664:PD885_RS19315
uniprot id: A0A1Y6HC46
names: Similarity
messages: Belongs to the GST superfamily.

48664:PD885 RS00270
gene id: 48664:PD885_RS00270
uniprot id: A0A1Y6H2F7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

48664:PD885 RS17085
gene id: 48664:PD885_RS17085
uniprot id: A0A1Y6HEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

48664:PD885 RS01175
gene id: 48664:PD885_RS01175
uniprot id: A0A1Y6H2Z2
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS13460
gene id: 48664:PD885_RS13460
uniprot id: A0A1Y6HEW5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS13200
gene id: 48664:PD885_RS13200
uniprot id: A0A1Y6HKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

48664:PD885 RS07840
gene id: 48664:PD885_RS07840
uniprot id: A0A1Y6H8G6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

48664:PD885 RS13250
gene id: 48664:PD885_RS13250
uniprot id: A0A1Y6H936
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

48664:PD885 RS04195
gene id: 48664:PD885_RS04195
uniprot id: A0A1Y6H3J4
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS17440
gene id: 48664:PD885_RS17440
uniprot id: A0A1Y6HGZ4
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

48664:PD885 RS06160
gene id: 48664:PD885_RS06160
uniprot id: A0A1Y6GYZ5
names: Function
names: Similarity
messages: Belongs to the MurL family.
messages: Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.

48664:PD885 RS12590
gene id: 48664:PD885_RS12590
uniprot id: A0A1Y6HJW1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

48664:PD885 RS02040
gene id: 48664:PD885_RS02040
uniprot id: A0A1Y6H599
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

48664:PD885 RS18225
gene id: 48664:PD885_RS18225
uniprot id: A0A1Y6HGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

48664:PD885 RS16680
gene id: 48664:PD885_RS16680
uniprot id: A0A1Y6HDH2
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS16615
gene id: 48664:PD885_RS16615
uniprot id: A0A1Y6HAL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

48664:PD885 RS10680
gene id: 48664:PD885_RS10680
uniprot id: A0A1Y6HA29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

48664:PD885 RS17780
gene id: 48664:PD885_RS17780
uniprot id: A0A1Y6HBR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

48664:PD885 RS15495
gene id: 48664:PD885_RS15495
uniprot id: A0A1Y6HAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

48664:PD885 RS05795
gene id: 48664:PD885_RS05795
uniprot id: A0A1Y6H813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS10770
gene id: 48664:PD885_RS10770
uniprot id: A0A1Y6GV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

48664:PD885 RS04105
gene id: 48664:PD885_RS04105
uniprot id: A0A1Y6H3J2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

48664:PD885 RS17675
gene id: 48664:PD885_RS17675
uniprot id: A0A1Y6HK30
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

48664:PD885 RS00895
gene id: 48664:PD885_RS00895
uniprot id: A0A1Y6HNJ1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

48664:PD885 RS11725
gene id: 48664:PD885_RS11725
uniprot id: A0A1Y6H880
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

48664:PD885 RS16045
gene id: 48664:PD885_RS16045
uniprot id: A0A1Y6HAA1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

48664:PD885 RS17335
gene id: 48664:PD885_RS17335
uniprot id: A0A1Y6HB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

48664:PD885 RS13545
gene id: 48664:PD885_RS13545
uniprot id: A0A1Y6GUX4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

48664:PD885 RS17075
gene id: 48664:PD885_RS17075
uniprot id: A0A1Y6HAX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

48664:PD885 RS18550
gene id: 48664:PD885_RS18550
uniprot id: A0A1Y6GRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS16010
gene id: 48664:PD885_RS16010
uniprot id: A0A1Y6H2Q0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

48664:PD885 RS09845
gene id: 48664:PD885_RS09845
uniprot id: A0A1Y6H6R1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

48664:PD885 RS13510
gene id: 48664:PD885_RS13510
uniprot id: A0A1Y6H8U9
names: Similarity
messages: Belongs to the DapA family.

48664:PD885 RS13315
gene id: 48664:PD885_RS13315
uniprot id: A0A1Y6HH24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

48664:PD885 RS16085
gene id: 48664:PD885_RS16085
uniprot id: A0A1Y6HIJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

48664:PD885 RS06660
gene id: 48664:PD885_RS06660
uniprot id: A0A1Y6H9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

48664:PD885 RS06980
gene id: 48664:PD885_RS06980
uniprot id: A0A1Y6H0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

48664:PD885 RS09140
gene id: 48664:PD885_RS09140
uniprot id: A0A1Y6H7E7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

48664:PD885 RS03285
gene id: 48664:PD885_RS03285
uniprot id: A0A1Y6H5Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

48664:PD885 RS09030
gene id: 48664:PD885_RS09030
uniprot id: A0A1Y6H687
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

48664:PD885 RS16260
gene id: 48664:PD885_RS16260
uniprot id: A0A1Y6HAE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

48664:PD885 RS00020
gene id: 48664:PD885_RS00020
uniprot id: A0A1Y6HCR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

48664:PD885 RS13110
gene id: 48664:PD885_RS13110
uniprot id: A0A1Y6HC60
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

48664:PD885 RS19970
gene id: 48664:PD885_RS19970
uniprot id: A0A1Y6HUP9
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS04025
gene id: 48664:PD885_RS04025
uniprot id: A0A1Y6H6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

48664:PD885 RS06960
gene id: 48664:PD885_RS06960
uniprot id: A0A1Y6HL40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

48664:PD885 RS12865
gene id: 48664:PD885_RS12865
uniprot id: A0A1Y6H8H2
names: Similarity
messages: Belongs to the PhoH family.

48664:PD885 RS05190
gene id: 48664:PD885_RS05190
uniprot id: A0A1Y6H447
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

48664:PD885 RS01765
gene id: 48664:PD885_RS01765
uniprot id: A0A1Y6H282
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

48664:PD885 RS12120
gene id: 48664:PD885_RS12120
uniprot id: A0A1Y6HE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

48664:PD885 RS08815
gene id: 48664:PD885_RS08815
uniprot id: A0A1Y6HC74
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

48664:PD885 RS04270
gene id: 48664:PD885_RS04270
uniprot id: A0A1Y6H774
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

48664:PD885 RS14650
gene id: 48664:PD885_RS14650
uniprot id: A0A1Y6HFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

48664:PD885 RS12605
gene id: 48664:PD885_RS12605
uniprot id: A0A1Y6HMI5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

48664:PD885 RS09200
gene id: 48664:PD885_RS09200
uniprot id: A0A1Y6HIB6
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS08070
gene id: 48664:PD885_RS08070
uniprot id: A0A1Y6H5R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

48664:PD885 RS09985
gene id: 48664:PD885_RS09985
uniprot id: A0A1Y6H7V8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

48664:PD885 RS17500
gene id: 48664:PD885_RS17500
uniprot id: A0A1Y6HE40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

48664:PD885 RS12750
gene id: 48664:PD885_RS12750
uniprot id: A0A1Y6HNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

48664:PD885 RS11735
gene id: 48664:PD885_RS11735
uniprot id: A0A1Y6H7W2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

48664:PD885 RS09525
gene id: 48664:PD885_RS09525
uniprot id: A0A1Y6H9D8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

48664:PD885 RS10815
gene id: 48664:PD885_RS10815
uniprot id: A0A1Y6HAU3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

48664:PD885 RS06345
gene id: 48664:PD885_RS06345
uniprot id: A0A1Y6H8D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

48664:PD885 RS06165
gene id: 48664:PD885_RS06165
uniprot id: A0A1Y6HL15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurD2 subfamily.
messages: Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

48664:PD885 RS14660
gene id: 48664:PD885_RS14660
uniprot id: A0A1Y6GYU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

48664:PD885 RS04635
gene id: 48664:PD885_RS04635
uniprot id: A0A1Y6H3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

48664:PD885 RS07760
gene id: 48664:PD885_RS07760
uniprot id: A0A1Y6H6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS01225
gene id: 48664:PD885_RS01225
uniprot id: A0A1Y6H302
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

48664:PD885 RS09540
gene id: 48664:PD885_RS09540
uniprot id: A0A1Y6HI45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

48664:PD885 RS03645
gene id: 48664:PD885_RS03645
uniprot id: A0A1Y6GS15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

48664:PD885 RS14565
gene id: 48664:PD885_RS14565
uniprot id: A0A1Y6HIM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

48664:PD885 RS09255
gene id: 48664:PD885_RS09255
uniprot id: A0A1Y6H6E4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS01390
gene id: 48664:PD885_RS01390
uniprot id: A0A1Y6H089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS19560
gene id: 48664:PD885_RS19560
uniprot id: A0A1Y6HUJ6
names: Similarity
messages: Belongs to the UPF0225 family.

48664:PD885 RS15455
gene id: 48664:PD885_RS15455
uniprot id: A0A1Y6HA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS10095
gene id: 48664:PD885_RS10095
uniprot id: A0A1Y6HIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

48664:PD885 RS15065
gene id: 48664:PD885_RS15065
uniprot id: A0A1Y6HD85
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

48664:PD885 RS09550
gene id: 48664:PD885_RS09550
uniprot id: A0A1Y6HJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

48664:PD885 RS15005
gene id: 48664:PD885_RS15005
uniprot id: A0A1Y6HA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS08480
gene id: 48664:PD885_RS08480
uniprot id: A0A1Y6H5Z1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

48664:PD885 RS06810
gene id: 48664:PD885_RS06810
uniprot id: A0A1Y6HL70
names: Similarity
messages: Belongs to the peptidase U62 family.

48664:PD885 RS04940
gene id: 48664:PD885_RS04940
uniprot id: A0A1Y6HPV9
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS13185
gene id: 48664:PD885_RS13185
uniprot id: A0A1Y6HLH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

48664:PD885 RS00540
gene id: 48664:PD885_RS00540
uniprot id: A0A1Y6GQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

48664:PD885 RS01510
gene id: 48664:PD885_RS01510
uniprot id: A0A1Y6H236
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

48664:PD885 RS13350
gene id: 48664:PD885_RS13350
uniprot id: A0A1Y6GXN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

48664:PD885 RS03470
gene id: 48664:PD885_RS03470
uniprot id: A0A1Y6HRV7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

48664:PD885 RS07470
gene id: 48664:PD885_RS07470
uniprot id: A0A1Y6GU28
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

48664:PD885 RS08575
gene id: 48664:PD885_RS08575
uniprot id: A0A1Y6HHK9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

48664:PD885 RS15055
gene id: 48664:PD885_RS15055
uniprot id: A0A1Y6HA51
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

48664:PD885 RS01795
gene id: 48664:PD885_RS01795
uniprot id: A0A1Y6GR40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

48664:PD885 RS03710
gene id: 48664:PD885_RS03710
uniprot id: A0A1Y6H9A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

48664:PD885 RS09110
gene id: 48664:PD885_RS09110
uniprot id: A0A1Y6H9W5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

48664:PD885 RS07835
gene id: 48664:PD885_RS07835
uniprot id: A0A1Y6H976
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

48664:PD885 RS16255
gene id: 48664:PD885_RS16255
uniprot id: A0A1Y6GZ74
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

48664:PD885 RS16145
gene id: 48664:PD885_RS16145
uniprot id: A0A1Y6HF35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

48664:PD885 RS08790
gene id: 48664:PD885_RS08790
uniprot id: A0A1Y6H6J8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

48664:PD885 RS06255
gene id: 48664:PD885_RS06255
uniprot id: A0A1Y6H2K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

48664:PD885 RS13715
gene id: 48664:PD885_RS13715
uniprot id: A0A1Y6GTK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

48664:PD885 RS06280
gene id: 48664:PD885_RS06280
uniprot id: A0A1Y6H4S1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS04550
gene id: 48664:PD885_RS04550
uniprot id: A0A1Y6H3Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

48664:PD885 RS09280
gene id: 48664:PD885_RS09280
uniprot id: A0A1Y6HMQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS07090
gene id: 48664:PD885_RS07090
uniprot id: A0A1Y6HB96
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

48664:PD885 RS06035
gene id: 48664:PD885_RS06035
uniprot id: A0A1Y6HKQ7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

48664:PD885 RS07990
gene id: 48664:PD885_RS07990
uniprot id: A0A1Y6HJY1
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS17315
gene id: 48664:PD885_RS17315
uniprot id: A0A1Y6HC37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Periplasm
messages: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.

48664:PD885 RS09660
gene id: 48664:PD885_RS09660
uniprot id: A0A1Y6H9H7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

48664:PD885 RS13785
gene id: 48664:PD885_RS13785
uniprot id: A0A1Y6H900
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

48664:PD885 RS11380
gene id: 48664:PD885_RS11380
uniprot id: A0A1Y6HMT8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

48664:PD885 RS01160
gene id: 48664:PD885_RS01160
uniprot id: A0A1Y6H1V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

48664:PD885 RS11035
gene id: 48664:PD885_RS11035
uniprot id: A0A1Y6HCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

48664:PD885 RS06975
gene id: 48664:PD885_RS06975
uniprot id: A0A1Y6HR27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

48664:PD885 RS07460
gene id: 48664:PD885_RS07460
uniprot id: A0A1Y6H5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

48664:PD885 RS03910
gene id: 48664:PD885_RS03910
uniprot id: A0A1Y6H3X3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS01490
gene id: 48664:PD885_RS01490
uniprot id: A0A1Y6H4X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

48664:PD885 RS06890
gene id: 48664:PD885_RS06890
uniprot id: A0A1Y6H519
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

48664:PD885 RS09215
gene id: 48664:PD885_RS09215
uniprot id: A0A1Y6H6D7
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS11530
gene id: 48664:PD885_RS11530
uniprot id: A0A1Y6H845
names: Similarity
messages: Belongs to the PhoH family.

48664:PD885 RS06645
gene id: 48664:PD885_RS06645
uniprot id: A0A1Y6H4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

48664:PD885 RS01575
gene id: 48664:PD885_RS01575
uniprot id: A0A1Y6H2M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

48664:PD885 RS04090
gene id: 48664:PD885_RS04090
uniprot id: A0A1Y6H4M1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

48664:PD885 RS08555
gene id: 48664:PD885_RS08555
uniprot id: A0A1Y6H9K1
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

48664:PD885 RS05070
gene id: 48664:PD885_RS05070
uniprot id: A0A1Y6GVX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

48664:PD885 RS17495
gene id: 48664:PD885_RS17495
uniprot id: A0A1Y6HEQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

48664:PD885 RS16105
gene id: 48664:PD885_RS16105
uniprot id: A0A1Y6HBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

48664:PD885 RS12105
gene id: 48664:PD885_RS12105
uniprot id: A0A1Y6HQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

48664:PD885 RS15325
gene id: 48664:PD885_RS15325
uniprot id: A0A1Y6H2H1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS02060
gene id: 48664:PD885_RS02060
uniprot id: A0A1Y6H2F2
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

48664:PD885 RS12455
gene id: 48664:PD885_RS12455
uniprot id: A0A1Y6HPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

48664:PD885 RS01735
gene id: 48664:PD885_RS01735
uniprot id: A0A1Y6H267
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

48664:PD885 RS18895
gene id: 48664:PD885_RS18895
uniprot id: A0A1Y6HCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

48664:PD885 RS13890
gene id: 48664:PD885_RS13890
uniprot id: A0A1Y6HG76
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

48664:PD885 RS07695
gene id: 48664:PD885_RS07695
uniprot id: A0A1Y6HHH6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

48664:PD885 RS02795
gene id: 48664:PD885_RS02795
uniprot id: A0A1Y6HR42
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

48664:PD885 RS07820
gene id: 48664:PD885_RS07820
uniprot id: A0A1Y6GX98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

48664:PD885 RS04885
gene id: 48664:PD885_RS04885
uniprot id: A0A1Y6H4G9
names: Similarity
messages: Belongs to the PspA/IM30 family.

48664:PD885 RS14075
gene id: 48664:PD885_RS14075
uniprot id: A0A1Y6HBZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

48664:PD885 RS12845
gene id: 48664:PD885_RS12845
uniprot id: A0A1Y6H8G7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

48664:PD885 RS01830
gene id: 48664:PD885_RS01830
uniprot id: A0A1Y6H5X5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

48664:PD885 RS17190
gene id: 48664:PD885_RS17190
uniprot id: A0A1Y6HFS9
names: Similarity
messages: Belongs to the peptidase S9A family.

48664:PD885 RS08040
gene id: 48664:PD885_RS08040
uniprot id: A0A1Y6H5Q6
names: Similarity
messages: Belongs to the glutamine synthetase family.

48664:PD885 RS08955
gene id: 48664:PD885_RS08955
uniprot id: A0A1Y6GUX8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

48664:PD885 RS14550
gene id: 48664:PD885_RS14550
uniprot id: A0A1Y6HFX2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

48664:PD885 RS19390
gene id: 48664:PD885_RS19390
uniprot id: A0A1Y6HI89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS08270
gene id: 48664:PD885_RS08270
uniprot id: A0A1Y6HHT2
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

48664:PD885 RS16575
gene id: 48664:PD885_RS16575
uniprot id: A0A1Y6GZE7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

48664:PD885 RS16340
gene id: 48664:PD885_RS16340
uniprot id: A0A1Y6HJN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

48664:PD885 RS12825
gene id: 48664:PD885_RS12825
uniprot id: A0A1Y6HHV3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

48664:PD885 RS06720
gene id: 48664:PD885_RS06720
uniprot id: A0A1Y6HR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

48664:PD885 RS03885
gene id: 48664:PD885_RS03885
uniprot id: A0A1Y6H871
names: Similarity
messages: Belongs to the ABC transporter superfamily.

48664:PD885 RS17215
gene id: 48664:PD885_RS17215
uniprot id: A0A1Y6HBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

48664:PD885 RS09530
gene id: 48664:PD885_RS09530
uniprot id: A0A1Y6HMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

48664:PD885 RS16890
gene id: 48664:PD885_RS16890
uniprot id: A0A1Y6HJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

48664:PD885 RS17100
gene id: 48664:PD885_RS17100
uniprot id: A0A1Y6HEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

48664:PD885 RS08080
gene id: 48664:PD885_RS08080
uniprot id: A0A1Y6HH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

48664:PD885 RS06825
gene id: 48664:PD885_RS06825
uniprot id: A0A1Y6H9X8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

48664:PD885 RS15750
gene id: 48664:PD885_RS15750
uniprot id: A0A1Y6HAJ3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

48664:PD885 RS01610
gene id: 48664:PD885_RS01610
uniprot id: A0A1Y6H501
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

48664:PD885 RS11590
gene id: 48664:PD885_RS11590
uniprot id: A0A1Y6HJA6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

48664:PD885 RS07250
gene id: 48664:PD885_RS07250
uniprot id: A0A1Y6H595
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS15355
gene id: 48664:PD885_RS15355
uniprot id: A0A1Y6H9Y6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

48664:PD885 RS05850
gene id: 48664:PD885_RS05850
uniprot id: A0A1Y6H4H9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

48664:PD885 RS06330
gene id: 48664:PD885_RS06330
uniprot id: A0A1Y6H596
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

48664:PD885 RS10915
gene id: 48664:PD885_RS10915
uniprot id: A0A1Y6HMJ0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

48664:PD885 RS14620
gene id: 48664:PD885_RS14620
uniprot id: A0A1Y6HJE8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

48664:PD885 RS17805
gene id: 48664:PD885_RS17805
uniprot id: A0A1Y6HG44
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

48664:PD885 RS09565
gene id: 48664:PD885_RS09565
uniprot id: A0A1Y6H6J7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

48664:PD885 RS10975
gene id: 48664:PD885_RS10975
uniprot id: A0A1Y6HAX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS19960
gene id: 48664:PD885_RS19960
uniprot id: A0A1Y6HRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

48664:PD885 RS14695
gene id: 48664:PD885_RS14695
uniprot id: A0A1Y6H9K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

48664:PD885 RS06770
gene id: 48664:PD885_RS06770
uniprot id: A0A1Y6H7W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

48664:PD885 RS14525
gene id: 48664:PD885_RS14525
uniprot id: A0A1Y6H1W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

48664:PD885 RS03065
gene id: 48664:PD885_RS03065
uniprot id: A0A1Y6H2H1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS06230
gene id: 48664:PD885_RS06230
uniprot id: A0A1Y6H7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

48664:PD885 RS17890
gene id: 48664:PD885_RS17890
uniprot id: A0A1Y6GW00
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

48664:PD885 RS03845
gene id: 48664:PD885_RS03845
uniprot id: A0A1Y6GW32
names: Similarity
messages: Belongs to the GSP E family.

48664:PD885 RS15645
gene id: 48664:PD885_RS15645
uniprot id: A0A1Y6HFA4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

48664:PD885 RS12940
gene id: 48664:PD885_RS12940
uniprot id: A0A1Y6GU08
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS08645
gene id: 48664:PD885_RS08645
uniprot id: A0A1Y6HMD1
names: Similarity
messages: Belongs to the SlyX family.

48664:PD885 RS04850
gene id: 48664:PD885_RS04850
uniprot id: A0A1Y6HLC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS17130
gene id: 48664:PD885_RS17130
uniprot id: A0A1Y6HH46
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

48664:PD885 RS16190
gene id: 48664:PD885_RS16190
uniprot id: A0A1Y6HD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

48664:PD885 RS10990
gene id: 48664:PD885_RS10990
uniprot id: A0A1Y6GYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

48664:PD885 RS00585
gene id: 48664:PD885_RS00585
uniprot id: A0A1Y6HP73
names: Similarity
messages: Belongs to the glutamate synthase family.

48664:PD885 RS09370
gene id: 48664:PD885_RS09370
uniprot id: A0A1Y6HA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

48664:PD885 RS13100
gene id: 48664:PD885_RS13100
uniprot id: A0A1Y6HGN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

48664:PD885 RS04870
gene id: 48664:PD885_RS04870
uniprot id: A0A1Y6H3X8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS08030
gene id: 48664:PD885_RS08030
uniprot id: A0A1Y6H656
names: Similarity
messages: Belongs to the glutamine synthetase family.

48664:PD885 RS16360
gene id: 48664:PD885_RS16360
uniprot id: A0A1Y6HF05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

48664:PD885 RS12695
gene id: 48664:PD885_RS12695
uniprot id: A0A1Y6H8S6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

48664:PD885 RS16100
gene id: 48664:PD885_RS16100
uniprot id: A0A1Y6HAB5
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

48664:PD885 RS09725
gene id: 48664:PD885_RS09725
uniprot id: A0A1Y6HI97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

48664:PD885 RS19450
gene id: 48664:PD885_RS19450
uniprot id: A0A1Y6HC94
names: Similarity
messages: Belongs to the DEAD box helicase family.

48664:PD885 RS17290
gene id: 48664:PD885_RS17290
uniprot id: A0A1Y6HE71
names: Similarity
messages: Belongs to the peptidase M16 family.

48664:PD885 RS00905
gene id: 48664:PD885_RS00905
uniprot id: A0A1Y6H7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS11565
gene id: 48664:PD885_RS11565
uniprot id: A0A1Y6HDS9
names: Similarity
messages: Belongs to the pirin family.

48664:PD885 RS05700
gene id: 48664:PD885_RS05700
uniprot id: A0A1Y6GY51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

48664:PD885 RS09995
gene id: 48664:PD885_RS09995
uniprot id: A0A1Y6H6V4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

48664:PD885 RS07805
gene id: 48664:PD885_RS07805
uniprot id: A0A1Y6H5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

48664:PD885 RS03440
gene id: 48664:PD885_RS03440
uniprot id: A0A1Y6H349
names: Similarity
messages: Belongs to the MotB family.

48664:PD885 RS14670
gene id: 48664:PD885_RS14670
uniprot id: A0A1Y6HJD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

48664:PD885 RS05185
gene id: 48664:PD885_RS05185
uniprot id: A0A1Y6GWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

48664:PD885 RS13710
gene id: 48664:PD885_RS13710
uniprot id: A0A1Y6HGG5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

48664:PD885 RS05475
gene id: 48664:PD885_RS05475
uniprot id: A0A1Y6H4A2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

48664:PD885 RS16460
gene id: 48664:PD885_RS16460
uniprot id: A0A1Y6HE15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

48664:PD885 RS14240
gene id: 48664:PD885_RS14240
uniprot id: A0A1Y6HGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

48664:PD885 RS00305
gene id: 48664:PD885_RS00305
uniprot id: A0A1Y6H494
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

48664:PD885 RS09800
gene id: 48664:PD885_RS09800
uniprot id: A0A1Y6HLX0
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS19680
gene id: 48664:PD885_RS19680
uniprot id: A0A1Y6HIE7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

48664:PD885 RS08680
gene id: 48664:PD885_RS08680
uniprot id: A0A1Y6H639
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

48664:PD885 RS14800
gene id: 48664:PD885_RS14800
uniprot id: A0A1Y6H9J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

48664:PD885 RS15960
gene id: 48664:PD885_RS15960
uniprot id: A0A1Y6HG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS13225
gene id: 48664:PD885_RS13225
uniprot id: A0A1Y6HDH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS00615
gene id: 48664:PD885_RS00615
uniprot id: A0A1Y6H228
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

48664:PD885 RS16375
gene id: 48664:PD885_RS16375
uniprot id: A0A1Y6HAG5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

48664:PD885 RS06985
gene id: 48664:PD885_RS06985
uniprot id: A0A1Y6H109
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS19065
gene id: 48664:PD885_RS19065
uniprot id: A0A1Y6HJA2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

48664:PD885 RS18470
gene id: 48664:PD885_RS18470
uniprot id: A0A1Y6HEH5
names: Similarity
messages: Belongs to the peptidase M17 family.

48664:PD885 RS02745
gene id: 48664:PD885_RS02745
uniprot id: A0A1Y6H2U0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

48664:PD885 RS16310
gene id: 48664:PD885_RS16310
uniprot id: A0A1Y6GZ86
names: Similarity
messages: Belongs to the UPF0149 family.

48664:PD885 RS11015
gene id: 48664:PD885_RS11015
uniprot id: A0A1Y6HJ00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

48664:PD885 RS07780
gene id: 48664:PD885_RS07780
uniprot id: A0A1Y6H964
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

48664:PD885 RS19950
gene id: 48664:PD885_RS19950
uniprot id: A0A1Y6HS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

48664:PD885 RS05825
gene id: 48664:PD885_RS05825
uniprot id: A0A1Y6H822
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

48664:PD885 RS18510
gene id: 48664:PD885_RS18510
uniprot id: A0A1Y6HCQ9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS07730
gene id: 48664:PD885_RS07730
uniprot id: A0A1Y6H8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

48664:PD885 RS14645
gene id: 48664:PD885_RS14645
uniprot id: A0A1Y6GYC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

48664:PD885 RS12645
gene id: 48664:PD885_RS12645
uniprot id: A0A1Y6H8R6
names: Similarity
messages: Belongs to the DEAD box helicase family.

48664:PD885 RS10115
gene id: 48664:PD885_RS10115
uniprot id: A0A1Y6HCZ0
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

48664:PD885 RS12500
gene id: 48664:PD885_RS12500
uniprot id: A0A1Y6HMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline. This is a step in an alternative arginine biosynthesis pathway.
messages: Cytoplasm
messages: Homotrimer.

48664:PD885 RS03880
gene id: 48664:PD885_RS03880
uniprot id: A0A1Y6H693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS15675
gene id: 48664:PD885_RS15675
uniprot id: A0A1Y6H2I4
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

48664:PD885 RS08755
gene id: 48664:PD885_RS08755
uniprot id: A0A1Y6GVZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

48664:PD885 RS17545
gene id: 48664:PD885_RS17545
uniprot id: A0A1Y6HHP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

48664:PD885 RS04700
gene id: 48664:PD885_RS04700
uniprot id: A0A1Y6HLF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

48664:PD885 RS15035
gene id: 48664:PD885_RS15035
uniprot id: A0A1Y6HEG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

48664:PD885 RS04050
gene id: 48664:PD885_RS04050
uniprot id: A0A1Y6H4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

48664:PD885 RS12775
gene id: 48664:PD885_RS12775
uniprot id: A0A1Y6HD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

48664:PD885 RS12220
gene id: 48664:PD885_RS12220
uniprot id: A0A1Y6HJP2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

48664:PD885 RS12485
gene id: 48664:PD885_RS12485
uniprot id: A0A1Y6GWY8
names: Subcellular Location Annotation
messages: Cytoplasm

48664:PD885 RS04655
gene id: 48664:PD885_RS04655
uniprot id: A0A1Y6H9U5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

48664:PD885 RS17815
gene id: 48664:PD885_RS17815
uniprot id: A0A1Y6HBA3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

48664:PD885 RS16250
gene id: 48664:PD885_RS16250
uniprot id: A0A1Y6HGG3
names: Similarity
messages: Belongs to the RutC family.

48664:PD885 RS14680
gene id: 48664:PD885_RS14680
uniprot id: A0A1Y6HAI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

48664:PD885 RS03580
gene id: 48664:PD885_RS03580
uniprot id: A0A1Y6GV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

48664:PD885 RS08460
gene id: 48664:PD885_RS08460
uniprot id: A0A1Y6GVT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS17610
gene id: 48664:PD885_RS17610
uniprot id: A0A1Y6HH94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS15910
gene id: 48664:PD885_RS15910
uniprot id: A0A1Y6HAM1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

48664:PD885 RS18625
gene id: 48664:PD885_RS18625
uniprot id: A0A1Y6HCS9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS09705
gene id: 48664:PD885_RS09705
uniprot id: A0A1Y6H9I7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS00210
gene id: 48664:PD885_RS00210
uniprot id: A0A1Y6H1D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

48664:PD885 RS10835
gene id: 48664:PD885_RS10835
uniprot id: A0A1Y6GZ04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

48664:PD885 RS12960
gene id: 48664:PD885_RS12960
uniprot id: A0A1Y6H8K3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

48664:PD885 RS17595
gene id: 48664:PD885_RS17595
uniprot id: A0A1Y6HHP0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

48664:PD885 RS17885
gene id: 48664:PD885_RS17885
uniprot id: A0A1Y6GWX3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS07875
gene id: 48664:PD885_RS07875
uniprot id: A0A1Y6GZD2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

48664:PD885 RS11030
gene id: 48664:PD885_RS11030
uniprot id: A0A1Y6HA79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

48664:PD885 RS03765
gene id: 48664:PD885_RS03765
uniprot id: A0A1Y6H853
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

48664:PD885 RS11745
gene id: 48664:PD885_RS11745
uniprot id: A0A1Y6HAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

48664:PD885 RS13720
gene id: 48664:PD885_RS13720
uniprot id: A0A1Y6GUC4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

48664:PD885 RS13235
gene id: 48664:PD885_RS13235
uniprot id: A0A1Y6H8N9
names: Similarity
messages: Belongs to the asparagine synthetase family.

48664:PD885 RS03575
gene id: 48664:PD885_RS03575
uniprot id: A0A1Y6HPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

48664:PD885 RS15955
gene id: 48664:PD885_RS15955
uniprot id: A0A1Y6GZ11
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

48664:PD885 RS10885
gene id: 48664:PD885_RS10885
uniprot id: A0A1Y6GYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

48664:PD885 RS07795
gene id: 48664:PD885_RS07795
uniprot id: A0A1Y6GV23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

48664:PD885 RS19330
gene id: 48664:PD885_RS19330
uniprot id: A0A1Y6HGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

48664:PD885 RS18705
gene id: 48664:PD885_RS18705
uniprot id: A0A1Y6HIB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

48664:PD885 RS17180
gene id: 48664:PD885_RS17180
uniprot id: A0A1Y6HAZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS16060
gene id: 48664:PD885_RS16060
uniprot id: A0A1Y6H2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

48664:PD885 RS09225
gene id: 48664:PD885_RS09225
uniprot id: A0A1Y6H6C0
names: Similarity
messages: Belongs to the UPF0111 family.

48664:PD885 RS08860
gene id: 48664:PD885_RS08860
uniprot id: A0A1Y6HB04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

48664:PD885 RS04405
gene id: 48664:PD885_RS04405
uniprot id: A0A1Y6HPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS07675
gene id: 48664:PD885_RS07675
uniprot id: A0A1Y6H093
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

48664:PD885 RS08545
gene id: 48664:PD885_RS08545
uniprot id: A0A1Y6H607
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

48664:PD885 RS02100
gene id: 48664:PD885_RS02100
uniprot id: A0A1Y6H2F6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

48664:PD885 RS07390
gene id: 48664:PD885_RS07390
uniprot id: A0A1Y6HNL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

48664:PD885 RS14700
gene id: 48664:PD885_RS14700
uniprot id: A0A1Y6GYD7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

48664:PD885 RS05120
gene id: 48664:PD885_RS05120
uniprot id: A0A1Y6H437
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

48664:PD885 RS14570
gene id: 48664:PD885_RS14570
uniprot id: A0A1Y6HJF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

48664:PD885 RS09285
gene id: 48664:PD885_RS09285
uniprot id: A0A1Y6H987
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

48664:PD885 RS11420
gene id: 48664:PD885_RS11420
uniprot id: A0A1Y6H7P0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

48664:PD885 RS01560
gene id: 48664:PD885_RS01560
uniprot id: A0A1Y6H048
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS11355
gene id: 48664:PD885_RS11355
uniprot id: A0A1Y6HQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

48664:PD885 RS09875
gene id: 48664:PD885_RS09875
uniprot id: A0A1Y6HIC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

48664:PD885 RS15665
gene id: 48664:PD885_RS15665
uniprot id: A0A1Y6GYV5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

48664:PD885 RS01090
gene id: 48664:PD885_RS01090
uniprot id: A0A1Y6HNK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS16265
gene id: 48664:PD885_RS16265
uniprot id: A0A1Y6HBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

48664:PD885 RS18745
gene id: 48664:PD885_RS18745
uniprot id: A0A1Y6HFD3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

48664:PD885 RS05085
gene id: 48664:PD885_RS05085
uniprot id: A0A1Y6HM57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

48664:PD885 RS13320
gene id: 48664:PD885_RS13320
uniprot id: A0A1Y6HBJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

48664:PD885 RS16685
gene id: 48664:PD885_RS16685
uniprot id: A0A1Y6HF48
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

48664:PD885 RS03670
gene id: 48664:PD885_RS03670
uniprot id: A0A1Y6H3B7
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

48664:PD885 RS15470
gene id: 48664:PD885_RS15470
uniprot id: A0A1Y6HCS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

48664:PD885 RS00295
gene id: 48664:PD885_RS00295
uniprot id: A0A1Y6H516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS01400
gene id: 48664:PD885_RS01400
uniprot id: A0A1Y6HNQ9
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS01285
gene id: 48664:PD885_RS01285
uniprot id: A0A1Y6HRZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

48664:PD885 RS02255
gene id: 48664:PD885_RS02255
uniprot id: A0A1Y6H5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS16275
gene id: 48664:PD885_RS16275
uniprot id: A0A1Y6HAF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

48664:PD885 RS04950
gene id: 48664:PD885_RS04950
uniprot id: A0A1Y6H404
names: Similarity
messages: Belongs to the peptidase S33 family.

48664:PD885 RS04685
gene id: 48664:PD885_RS04685
uniprot id: A0A1Y6HLU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

48664:PD885 RS05310
gene id: 48664:PD885_RS05310
uniprot id: A0A1Y6H475
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

48664:PD885 RS01230
gene id: 48664:PD885_RS01230
uniprot id: A0A1Y6H2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS10660
gene id: 48664:PD885_RS10660
uniprot id: A0A1Y6H7L2
names: Similarity
messages: Belongs to the YfgM family.

48664:PD885 RS00120
gene id: 48664:PD885_RS00120
uniprot id: A0A1Y6H464
names: Similarity
messages: Belongs to the peptidase S41A family.

48664:PD885 RS16320
gene id: 48664:PD885_RS16320
uniprot id: A0A1Y6HEW1
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

48664:PD885 RS19775
gene id: 48664:PD885_RS19775
uniprot id: A0A1Y6HFZ3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

48664:PD885 RS10015
gene id: 48664:PD885_RS10015
uniprot id: A0A1Y6HCX0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

48664:PD885 RS05885
gene id: 48664:PD885_RS05885
uniprot id: A0A1Y6HKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

48664:PD885 RS00760
gene id: 48664:PD885_RS00760
uniprot id: A0A1Y6HNN1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

48664:PD885 RS17040
gene id: 48664:PD885_RS17040
uniprot id: A0A1Y6HH69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

48664:PD885 RS04575
gene id: 48664:PD885_RS04575
uniprot id: A0A1Y6GSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

48664:PD885 RS05805
gene id: 48664:PD885_RS05805
uniprot id: A0A1Y6HAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

48664:PD885 RS02065
gene id: 48664:PD885_RS02065
uniprot id: A0A1Y6H3J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS01580
gene id: 48664:PD885_RS01580
uniprot id: A0A1Y6H242
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

48664:PD885 RS08800
gene id: 48664:PD885_RS08800
uniprot id: A0A1Y6H0U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

48664:PD885 RS00050
gene id: 48664:PD885_RS00050
uniprot id: A0A1Y6H736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

48664:PD885 RS12205
gene id: 48664:PD885_RS12205
uniprot id: A0A1Y6H854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

48664:PD885 RS13335
gene id: 48664:PD885_RS13335
uniprot id: A0A1Y6H8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

48664:PD885 RS12640
gene id: 48664:PD885_RS12640
uniprot id: A0A1Y6HJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

48664:PD885 RS00240
gene id: 48664:PD885_RS00240
uniprot id: A0A1Y6HIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

48664:PD885 RS05215
gene id: 48664:PD885_RS05215
uniprot id: A0A1Y6HM38
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

48664:PD885 RS05905
gene id: 48664:PD885_RS05905
uniprot id: A0A1Y6H4G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS00535
gene id: 48664:PD885_RS00535
uniprot id: A0A1Y6H1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

48664:PD885 RS05430
gene id: 48664:PD885_RS05430
uniprot id: A0A1Y6H931
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

48664:PD885 RS18865
gene id: 48664:PD885_RS18865
uniprot id: A0A1Y6H0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

48664:PD885 RS16700
gene id: 48664:PD885_RS16700
uniprot id: A0A1Y6HEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

48664:PD885 RS13120
gene id: 48664:PD885_RS13120
uniprot id: A0A1Y6HEP0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

48664:PD885 RS10960
gene id: 48664:PD885_RS10960
uniprot id: A0A1Y6GW99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

48664:PD885 RS06805
gene id: 48664:PD885_RS06805
uniprot id: A0A1Y6HKN3
names: Similarity
messages: Belongs to the UPF0307 family.

48664:PD885 RS15360
gene id: 48664:PD885_RS15360
uniprot id: A0A1Y6H9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

48664:PD885 RS18700
gene id: 48664:PD885_RS18700
uniprot id: A0A1Y6H5A1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

48664:PD885 RS16020
gene id: 48664:PD885_RS16020
uniprot id: A0A1Y6HA96
names: Similarity
messages: Belongs to the Nudix hydrolase family.

48664:PD885 RS13900
gene id: 48664:PD885_RS13900
uniprot id: A0A1Y6HGP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

48664:PD885 RS06630
gene id: 48664:PD885_RS06630
uniprot id: A0A1Y6HKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

48664:PD885 RS19430
gene id: 48664:PD885_RS19430
uniprot id: A0A1Y6HF01
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

48664:PD885 RS01405
gene id: 48664:PD885_RS01405
uniprot id: A0A1Y6HPD6
names: Subcellular Location Annotation
messages: Membrane

48664:PD885 RS07200
gene id: 48664:PD885_RS07200
uniprot id: A0A1Y6HA56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

48664:PD885 RS00115
gene id: 48664:PD885_RS00115
uniprot id: A0A1Y6H4Y5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

48664:PD885 RS14545
gene id: 48664:PD885_RS14545
uniprot id: A0A1Y6HFX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

48664:PD885 RS04695
gene id: 48664:PD885_RS04695
uniprot id: A0A1Y6HLE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

48664:PD885 RS00400
gene id: 48664:PD885_RS00400
uniprot id: A0A1Y6H1Z2
names: Similarity
messages: Belongs to the UPF0502 family.

48664:PD885 RS16075
gene id: 48664:PD885_RS16075
uniprot id: A0A1Y6HJT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

48664:PD885 RS05175
gene id: 48664:PD885_RS05175
uniprot id: A0A1Y6H435
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

48664:PD885 RS03130
gene id: 48664:PD885_RS03130
uniprot id: A0A1Y6HMS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

48664:PD885 RS05355
gene id: 48664:PD885_RS05355
uniprot id: A0A1Y6H478
names: Similarity
messages: Belongs to the peptidase S9C family.

48664:PD885 RS18495
gene id: 48664:PD885_RS18495
uniprot id: A0A1Y6HJK1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

48664:PD885 RS07465
gene id: 48664:PD885_RS07465
uniprot id: A0A1Y6GU49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

48664:PD885 RS06605
gene id: 48664:PD885_RS06605
uniprot id: A0A1Y6H7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

48664:PD885 RS00545
gene id: 48664:PD885_RS00545
uniprot id: A0A1Y6HNS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

48664:PD885 RS04425
gene id: 48664:PD885_RS04425
uniprot id: A0A1Y6H3Q4
names: Similarity
messages: Belongs to the IucA/IucC family.

48664:PD885 RS13260
gene id: 48664:PD885_RS13260
uniprot id: A0A1Y6H8Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

48664:PD885 RS03270
gene id: 48664:PD885_RS03270
uniprot id: A0A1Y6HMP0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.