Catalyzes the conversion of (2Z,6E)-farnesyl diphosphate (FPP) to yield the bicyclic sesquiterpene (1S,6S,7R)-(-)-gamma-cadinene via a 1,10-cyclization, which requires the abstraction of the pyrophosphate from FPP to yield a germacradienyl cation (PubMed:23307484, PubMed:27666571, PubMed:27829890). The only accepted substrate is (2Z,6E)-farnesyl diphosphate (FPP) (PubMed:27829890).
The Asp-Asp-Xaa-Xaa-Asp (DDXXD) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Belongs to the chorismate synthase family.
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).