479435:KFLA RS19465
gene id: 479435:KFLA_RS19465
uniprot id: D2PR22
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS14435
gene id: 479435:KFLA_RS14435
uniprot id: D2Q0I8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS09450
gene id: 479435:KFLA_RS09450
uniprot id: D2PPP3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479435:KFLA RS07675
gene id: 479435:KFLA_RS07675
uniprot id: D2PLM5
names: Caution
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS04710
gene id: 479435:KFLA_RS04710
uniprot id: D2Q064
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15525
gene id: 479435:KFLA_RS15525
uniprot id: D2Q372
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

479435:KFLA RS32535
gene id: 479435:KFLA_RS32535
uniprot id: D2PYH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

479435:KFLA RS21500
gene id: 479435:KFLA_RS21500
uniprot id: D2PV85
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS10495
gene id: 479435:KFLA_RS10495
uniprot id: D2PS83
names: Similarity
messages: Belongs to the hyi family.

479435:KFLA RS35495
gene id: 479435:KFLA_RS35495
uniprot id: D2PTN5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS23455
gene id: 479435:KFLA_RS23455
uniprot id: D2PZE2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS07165
gene id: 479435:KFLA_RS07165
uniprot id: D2PKP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS26960
gene id: 479435:KFLA_RS26960
uniprot id: D2PM80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

479435:KFLA RS26480
gene id: 479435:KFLA_RS26480
uniprot id: D2PLA2
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

479435:KFLA RS11850
gene id: 479435:KFLA_RS11850
uniprot id: D2PV03
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

479435:KFLA RS33140
gene id: 479435:KFLA_RS33140
uniprot id: D2PZU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

479435:KFLA RS22585
gene id: 479435:KFLA_RS22585
uniprot id: D2PXX1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS11295
gene id: 479435:KFLA_RS11295
uniprot id: D2PTP9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

479435:KFLA RS10395
gene id: 479435:KFLA_RS10395
uniprot id: D2PS63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

479435:KFLA RS34105
gene id: 479435:KFLA_RS34105
uniprot id: D2Q2F6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09385
gene id: 479435:KFLA_RS09385
uniprot id: D2PPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS37935
gene id: 479435:KFLA_RS37935
uniprot id: D2PYZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

479435:KFLA RS28610
gene id: 479435:KFLA_RS28610
uniprot id: D2PQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

479435:KFLA RS08895
gene id: 479435:KFLA_RS08895
uniprot id: D2PNP4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

479435:KFLA RS28500
gene id: 479435:KFLA_RS28500
uniprot id: D2PQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS00625
gene id: 479435:KFLA_RS00625
uniprot id: D2PRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS06710
gene id: 479435:KFLA_RS06710
uniprot id: D2PKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS31680
gene id: 479435:KFLA_RS31680
uniprot id: D2PWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

479435:KFLA RS13010
gene id: 479435:KFLA_RS13010
uniprot id: D2PXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS09325
gene id: 479435:KFLA_RS09325
uniprot id: D2PPL8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

479435:KFLA RS30430
gene id: 479435:KFLA_RS30430
uniprot id: D2PU83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

479435:KFLA RS26070
gene id: 479435:KFLA_RS26070
uniprot id: D2PL17
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

479435:KFLA RS21660
gene id: 479435:KFLA_RS21660
uniprot id: D2PVB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

479435:KFLA RS31795
gene id: 479435:KFLA_RS31795
uniprot id: D2PX19
names: Cofactor
messages: Binds 1 FAD per subunit.

479435:KFLA RS24210
gene id: 479435:KFLA_RS24210
uniprot id: D2Q0V0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

479435:KFLA RS31860
gene id: 479435:KFLA_RS31860
uniprot id: D2PX31
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS11830
gene id: 479435:KFLA_RS11830
uniprot id: D2PUZ9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09555
gene id: 479435:KFLA_RS09555
uniprot id: D2PQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS30615
gene id: 479435:KFLA_RS30615
uniprot id: D2PUB9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

479435:KFLA RS18705
gene id: 479435:KFLA_RS18705
uniprot id: D2PP02
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

479435:KFLA RS23385
gene id: 479435:KFLA_RS23385
uniprot id: D2PZC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS16130
gene id: 479435:KFLA_RS16130
uniprot id: D2Q4K0
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS24030
gene id: 479435:KFLA_RS24030
uniprot id: D2Q0R5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS08810
gene id: 479435:KFLA_RS08810
uniprot id: D2PNM8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS10460
gene id: 479435:KFLA_RS10460
uniprot id: D2PS76
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

479435:KFLA RS28945
gene id: 479435:KFLA_RS28945
uniprot id: D2PQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS20300
gene id: 479435:KFLA_RS20300
uniprot id: D2PSJ3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS03860
gene id: 479435:KFLA_RS03860
uniprot id: D2PYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS22050
gene id: 479435:KFLA_RS22050
uniprot id: D2PWK6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30940
gene id: 479435:KFLA_RS30940
uniprot id: D2PVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

479435:KFLA RS31250
gene id: 479435:KFLA_RS31250
uniprot id: D2PVQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS15580
gene id: 479435:KFLA_RS15580
uniprot id: D2Q383
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS34790
gene id: 479435:KFLA_RS34790
uniprot id: D2Q3W7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

479435:KFLA RS12120
gene id: 479435:KFLA_RS12120
uniprot id: D2PW71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

479435:KFLA RS10205
gene id: 479435:KFLA_RS10205
uniprot id: D2PS27
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS20140
gene id: 479435:KFLA_RS20140
uniprot id: D2PSG4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS16140
gene id: 479435:KFLA_RS16140
uniprot id: D2Q4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

479435:KFLA RS04940
gene id: 479435:KFLA_RS04940
uniprot id: D2Q1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS05965
gene id: 479435:KFLA_RS05965
uniprot id: D2Q2Y1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

479435:KFLA RS04880
gene id: 479435:KFLA_RS04880
uniprot id: D2Q1A9
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

479435:KFLA RS16655
gene id: 479435:KFLA_RS16655
uniprot id: D2PKU6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29080
gene id: 479435:KFLA_RS29080
uniprot id: D2PRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS22335
gene id: 479435:KFLA_RS22335
uniprot id: D2PWR1
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS09395
gene id: 479435:KFLA_RS09395
uniprot id: D2PPN2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of cyclobis-(1-6)-alpha-nigerosyl (CNN) degrading enzymes.

479435:KFLA RS18535
gene id: 479435:KFLA_RS18535
uniprot id: D2PNW9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

479435:KFLA RS12350
gene id: 479435:KFLA_RS12350
uniprot id: D2PWB8
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS20990
gene id: 479435:KFLA_RS20990
uniprot id: D2PTY4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS00960
gene id: 479435:KFLA_RS00960
uniprot id: D2PRZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

479435:KFLA RS01210
gene id: 479435:KFLA_RS01210
uniprot id: D2PT55
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS28005
gene id: 479435:KFLA_RS28005
uniprot id: D2PP56
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25265
gene id: 479435:KFLA_RS25265
uniprot id: D2Q3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

479435:KFLA RS13055
gene id: 479435:KFLA_RS13055
uniprot id: D2PXR6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

479435:KFLA RS27085
gene id: 479435:KFLA_RS27085
uniprot id: D2PMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS02000
gene id: 479435:KFLA_RS02000
uniprot id: D2PUK6
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS00630
gene id: 479435:KFLA_RS00630
uniprot id: D2PRS4
names: Similarity
messages: Belongs to the DapA family.

479435:KFLA RS32580
gene id: 479435:KFLA_RS32580
uniprot id: D2PZI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS23535
gene id: 479435:KFLA_RS23535
uniprot id: D2PZF8
names: Similarity
messages: Belongs to the UPF0102 family.

479435:KFLA RS27050
gene id: 479435:KFLA_RS27050
uniprot id: D2PM97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

479435:KFLA RS22915
gene id: 479435:KFLA_RS22915
uniprot id: D2PY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS05640
gene id: 479435:KFLA_RS05640
uniprot id: D2Q2R7
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS20250
gene id: 479435:KFLA_RS20250
uniprot id: D2PSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS09275
gene id: 479435:KFLA_RS09275
uniprot id: D2PPK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS00235
gene id: 479435:KFLA_RS00235
uniprot id: D2PQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS13725
gene id: 479435:KFLA_RS13725
uniprot id: D2PZ44
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS15770
gene id: 479435:KFLA_RS15770
uniprot id: D2Q4D2
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

479435:KFLA RS34155
gene id: 479435:KFLA_RS34155
uniprot id: D2Q2G5
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

479435:KFLA RS33335
gene id: 479435:KFLA_RS33335
uniprot id: D2Q100
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

479435:KFLA RS09745
gene id: 479435:KFLA_RS09745
uniprot id: D2PQT2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14115
gene id: 479435:KFLA_RS14115
uniprot id: D2Q0C4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

479435:KFLA RS04885
gene id: 479435:KFLA_RS04885
uniprot id: D2Q1B0
names: Subcellular Location Annotation
messages: Cytoplasm

479435:KFLA RS29340
gene id: 479435:KFLA_RS29340
uniprot id: D2PRJ7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

479435:KFLA RS22090
gene id: 479435:KFLA_RS22090
uniprot id: D2PWL4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

479435:KFLA RS04515
gene id: 479435:KFLA_RS04515
uniprot id: D2Q024
names: Similarity
messages: Belongs to the tannase family.

479435:KFLA RS27045
gene id: 479435:KFLA_RS27045
uniprot id: D2PM96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

479435:KFLA RS33305
gene id: 479435:KFLA_RS33305
uniprot id: D2Q0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479435:KFLA RS30220
gene id: 479435:KFLA_RS30220
uniprot id: D2PU41
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS05385
gene id: 479435:KFLA_RS05385
uniprot id: D2Q2L6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS34455
gene id: 479435:KFLA_RS34455
uniprot id: D2Q3Q1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

479435:KFLA RS24635
gene id: 479435:KFLA_RS24635
uniprot id: D2Q240
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS25020
gene id: 479435:KFLA_RS25020
uniprot id: D2Q3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

479435:KFLA RS16850
gene id: 479435:KFLA_RS16850
uniprot id: D2PKY5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

479435:KFLA RS22475
gene id: 479435:KFLA_RS22475
uniprot id: D2PWT8
names: Similarity
messages: Belongs to the IlvD/Edd family.

479435:KFLA RS22640
gene id: 479435:KFLA_RS22640
uniprot id: D2PXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS31985
gene id: 479435:KFLA_RS31985
uniprot id: D2PX56
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15675
gene id: 479435:KFLA_RS15675
uniprot id: D2Q3A2
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS23765
gene id: 479435:KFLA_RS23765
uniprot id: D2Q0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

479435:KFLA RS05660
gene id: 479435:KFLA_RS05660
uniprot id: D2Q2S1
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS05995
gene id: 479435:KFLA_RS05995
uniprot id: D2Q404
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

479435:KFLA RS23910
gene id: 479435:KFLA_RS23910
uniprot id: D2Q0P2
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

479435:KFLA RS06750
gene id: 479435:KFLA_RS06750
uniprot id: D2PKF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS05430
gene id: 479435:KFLA_RS05430
uniprot id: D2Q2M5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

479435:KFLA RS12600
gene id: 479435:KFLA_RS12600
uniprot id: D2PWG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

479435:KFLA RS06635
gene id: 479435:KFLA_RS06635
uniprot id: D2PKD4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

479435:KFLA RS00760
gene id: 479435:KFLA_RS00760
uniprot id: D2PRV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS01180
gene id: 479435:KFLA_RS01180
uniprot id: D2PT48
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS32440
gene id: 479435:KFLA_RS32440
uniprot id: D2PYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

479435:KFLA RS28290
gene id: 479435:KFLA_RS28290
uniprot id: D2PPB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

479435:KFLA RS13235
gene id: 479435:KFLA_RS13235
uniprot id: D2PXV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

479435:KFLA RS08535
gene id: 479435:KFLA_RS08535
uniprot id: D2PNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS12860
gene id: 479435:KFLA_RS12860
uniprot id: D2PXM6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS13550
gene id: 479435:KFLA_RS13550
uniprot id: D2PZ09
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

479435:KFLA RS33705
gene id: 479435:KFLA_RS33705
uniprot id: D2Q172
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

479435:KFLA RS32290
gene id: 479435:KFLA_RS32290
uniprot id: D2PYD0
names: Similarity
messages: Belongs to the peptidase S9A family.

479435:KFLA RS00245
gene id: 479435:KFLA_RS00245
uniprot id: D2PQJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

479435:KFLA RS24705
gene id: 479435:KFLA_RS24705
uniprot id: D2Q255
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

479435:KFLA RS00225
gene id: 479435:KFLA_RS00225
uniprot id: D2PQI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

479435:KFLA RS10140
gene id: 479435:KFLA_RS10140
uniprot id: D2PR09
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS12050
gene id: 479435:KFLA_RS12050
uniprot id: D2PW57
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS24490
gene id: 479435:KFLA_RS24490
uniprot id: D2Q210
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

479435:KFLA RS24715
gene id: 479435:KFLA_RS24715
uniprot id: D2Q257
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

479435:KFLA RS01560
gene id: 479435:KFLA_RS01560
uniprot id: D2PTC2
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

479435:KFLA RS12410
gene id: 479435:KFLA_RS12410
uniprot id: D2PWD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

479435:KFLA RS32555
gene id: 479435:KFLA_RS32555
uniprot id: D2PYI2
names: Similarity
messages: Belongs to the DapA family.

479435:KFLA RS26965
gene id: 479435:KFLA_RS26965
uniprot id: D2PM81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

479435:KFLA RS10610
gene id: 479435:KFLA_RS10610
uniprot id: D2PSA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS00255
gene id: 479435:KFLA_RS00255
uniprot id: D2PQJ3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS31930
gene id: 479435:KFLA_RS31930
uniprot id: D2PX45
names: Similarity
messages: Belongs to the Nth/MutY family.

479435:KFLA RS29680
gene id: 479435:KFLA_RS29680
uniprot id: D2PST1
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS28265
gene id: 479435:KFLA_RS28265
uniprot id: D2PPA7
names: Similarity
messages: Belongs to the KptA/TPT1 family.

479435:KFLA RS03915
gene id: 479435:KFLA_RS03915
uniprot id: D2PYQ8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS33535
gene id: 479435:KFLA_RS33535
uniprot id: D2Q139
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS25085
gene id: 479435:KFLA_RS25085
uniprot id: D2Q3F4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

479435:KFLA RS06670
gene id: 479435:KFLA_RS06670
uniprot id: D2PKE1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

479435:KFLA RS31470
gene id: 479435:KFLA_RS31470
uniprot id: D2PWV7
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

479435:KFLA RS07035
gene id: 479435:KFLA_RS07035
uniprot id: D2PKL3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

479435:KFLA RS00310
gene id: 479435:KFLA_RS00310
uniprot id: D2PQK4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS19245
gene id: 479435:KFLA_RS19245
uniprot id: D2PQ03
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS05980
gene id: 479435:KFLA_RS05980
uniprot id: D2Q401
names: Similarity
messages: Belongs to the peptidase M24B family.

479435:KFLA RS23505
gene id: 479435:KFLA_RS23505
uniprot id: D2PZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

479435:KFLA RS21455
gene id: 479435:KFLA_RS21455
uniprot id: D2PV74
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS33550
gene id: 479435:KFLA_RS33550
uniprot id: D2Q142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS21435
gene id: 479435:KFLA_RS21435
uniprot id: D2PV70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

479435:KFLA RS25600
gene id: 479435:KFLA_RS25600
uniprot id: D2Q4S3
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

479435:KFLA RS05275
gene id: 479435:KFLA_RS05275
uniprot id: D2Q1I8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS28230
gene id: 479435:KFLA_RS28230
uniprot id: D2PPA0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

479435:KFLA RS10465
gene id: 479435:KFLA_RS10465
uniprot id: D2PS77
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

479435:KFLA RS17215
gene id: 479435:KFLA_RS17215
uniprot id: D2PLU2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21170
gene id: 479435:KFLA_RS21170
uniprot id: D2PU15
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS06650
gene id: 479435:KFLA_RS06650
uniprot id: D2PKD7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

479435:KFLA RS04560
gene id: 479435:KFLA_RS04560
uniprot id: D2Q034
names: Similarity
messages: Belongs to the cytochrome P450 family.

479435:KFLA RS05310
gene id: 479435:KFLA_RS05310
uniprot id: D2Q1J5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS15765
gene id: 479435:KFLA_RS15765
uniprot id: D2Q4D1
names: Similarity
messages: Belongs to the IucA/IucC family.

479435:KFLA RS04460
gene id: 479435:KFLA_RS04460
uniprot id: D2Q012
names: Similarity
messages: Belongs to the type IB topoisomerase family.

479435:KFLA RS15715
gene id: 479435:KFLA_RS15715
uniprot id: D2Q4C1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

479435:KFLA RS15925
gene id: 479435:KFLA_RS15925
uniprot id: D2Q4G2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

479435:KFLA RS34715
gene id: 479435:KFLA_RS34715
uniprot id: D2Q3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS08365
gene id: 479435:KFLA_RS08365
uniprot id: D2PND7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

479435:KFLA RS08410
gene id: 479435:KFLA_RS08410
uniprot id: D2PNE7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS07750
gene id: 479435:KFLA_RS07750
uniprot id: D2PLP0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

479435:KFLA RS15180
gene id: 479435:KFLA_RS15180
uniprot id: D2Q304
names: Similarity
messages: Belongs to the TrpC family.

479435:KFLA RS11110
gene id: 479435:KFLA_RS11110
uniprot id: D2PTL5
names: Similarity
messages: Belongs to the FPG family.

479435:KFLA RS16200
gene id: 479435:KFLA_RS16200
uniprot id: D2Q4L4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

479435:KFLA RS13730
gene id: 479435:KFLA_RS13730
uniprot id: D2PZ45
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS32860
gene id: 479435:KFLA_RS32860
uniprot id: D2PZP4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS39155
gene id: 479435:KFLA_RS39155
uniprot id: D2PX08
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS27900
gene id: 479435:KFLA_RS27900
uniprot id: D2PP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS24370
gene id: 479435:KFLA_RS24370
uniprot id: D2Q1Y6
names: Similarity
messages: Belongs to the peptidase S9C family.

479435:KFLA RS10455
gene id: 479435:KFLA_RS10455
uniprot id: D2PS75
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

479435:KFLA RS31905
gene id: 479435:KFLA_RS31905
uniprot id: D2PX40
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

479435:KFLA RS20515
gene id: 479435:KFLA_RS20515
uniprot id: D2PSN7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

479435:KFLA RS03110
gene id: 479435:KFLA_RS03110
uniprot id: D2PX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

479435:KFLA RS02770
gene id: 479435:KFLA_RS02770
uniprot id: D2PW19
names: Similarity
messages: Belongs to the GSP E family.

479435:KFLA RS11245
gene id: 479435:KFLA_RS11245
uniprot id: D2PTP1
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS14375
gene id: 479435:KFLA_RS14375
uniprot id: D2Q0H5
names: Subcellular Location Annotation
messages: Cytoplasm

479435:KFLA RS02900
gene id: 479435:KFLA_RS02900
uniprot id: D2PW46
names: Similarity
messages: Belongs to the Fur family.

479435:KFLA RS30635
gene id: 479435:KFLA_RS30635
uniprot id: D2PUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

479435:KFLA RS02775
gene id: 479435:KFLA_RS02775
uniprot id: D2PW20
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS11290
gene id: 479435:KFLA_RS11290
uniprot id: D2PTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

479435:KFLA RS13310
gene id: 479435:KFLA_RS13310
uniprot id: D2PYW2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

479435:KFLA RS10555
gene id: 479435:KFLA_RS10555
uniprot id: D2PS95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

479435:KFLA RS10915
gene id: 479435:KFLA_RS10915
uniprot id: D2PTH6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

479435:KFLA RS31225
gene id: 479435:KFLA_RS31225
uniprot id: D2PVQ0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS34010
gene id: 479435:KFLA_RS34010
uniprot id: D2Q2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS20865
gene id: 479435:KFLA_RS20865
uniprot id: D2PTW0
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS06170
gene id: 479435:KFLA_RS06170
uniprot id: D2Q439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

479435:KFLA RS20130
gene id: 479435:KFLA_RS20130
uniprot id: D2PSG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

479435:KFLA RS05985
gene id: 479435:KFLA_RS05985
uniprot id: D2Q402
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

479435:KFLA RS31120
gene id: 479435:KFLA_RS31120
uniprot id: D2PVM9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

479435:KFLA RS18375
gene id: 479435:KFLA_RS18375
uniprot id: D2PNT7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

479435:KFLA RS00125
gene id: 479435:KFLA_RS00125
uniprot id: D2PQG7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

479435:KFLA RS30210
gene id: 479435:KFLA_RS30210
uniprot id: D2PU39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

479435:KFLA RS05530
gene id: 479435:KFLA_RS05530
uniprot id: D2Q2P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS28935
gene id: 479435:KFLA_RS28935
uniprot id: D2PQD2
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS30415
gene id: 479435:KFLA_RS30415
uniprot id: D2PU80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

479435:KFLA RS15275
gene id: 479435:KFLA_RS15275
uniprot id: D2Q322
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS33810
gene id: 479435:KFLA_RS33810
uniprot id: D2Q298
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

479435:KFLA RS05115
gene id: 479435:KFLA_RS05115
uniprot id: D2Q1F6
names: Similarity
messages: Belongs to the peptidase S1 family.

479435:KFLA RS00805
gene id: 479435:KFLA_RS00805
uniprot id: D2PRW0
names: Similarity
messages: Belongs to the peptidase S66 family.

479435:KFLA RS03680
gene id: 479435:KFLA_RS03680
uniprot id: D2PYL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

479435:KFLA RS21470
gene id: 479435:KFLA_RS21470
uniprot id: D2PV78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS31440
gene id: 479435:KFLA_RS31440
uniprot id: D2PWV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS14420
gene id: 479435:KFLA_RS14420
uniprot id: D2Q0I5
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS24545
gene id: 479435:KFLA_RS24545
uniprot id: D2Q222
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

479435:KFLA RS24710
gene id: 479435:KFLA_RS24710
uniprot id: D2Q256
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479435:KFLA RS25585
gene id: 479435:KFLA_RS25585
uniprot id: D2Q4S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

479435:KFLA RS26955
gene id: 479435:KFLA_RS26955
uniprot id: D2PM79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

479435:KFLA RS31475
gene id: 479435:KFLA_RS31475
uniprot id: D2PWV8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS12155
gene id: 479435:KFLA_RS12155
uniprot id: D2PW78
names: Similarity
messages: Belongs to the Fur family.

479435:KFLA RS25135
gene id: 479435:KFLA_RS25135
uniprot id: D2Q3G4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17980
gene id: 479435:KFLA_RS17980
uniprot id: D2PMX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

479435:KFLA RS22750
gene id: 479435:KFLA_RS22750
uniprot id: D2PY05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS04235
gene id: 479435:KFLA_RS04235
uniprot id: D2PZW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS04475
gene id: 479435:KFLA_RS04475
uniprot id: D2Q015
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS25040
gene id: 479435:KFLA_RS25040
uniprot id: D2Q3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

479435:KFLA RS11870
gene id: 479435:KFLA_RS11870
uniprot id: D2PV07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS09330
gene id: 479435:KFLA_RS09330
uniprot id: D2PPL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

479435:KFLA RS38695
gene id: 479435:KFLA_RS38695
uniprot id: D2Q008
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

479435:KFLA RS21545
gene id: 479435:KFLA_RS21545
uniprot id: D2PV94
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS01105
gene id: 479435:KFLA_RS01105
uniprot id: D2PT34
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS22880
gene id: 479435:KFLA_RS22880
uniprot id: D2PY33
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS31980
gene id: 479435:KFLA_RS31980
uniprot id: D2PX55
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS29220
gene id: 479435:KFLA_RS29220
uniprot id: D2PRH4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30825
gene id: 479435:KFLA_RS30825
uniprot id: D2PVG9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS27955
gene id: 479435:KFLA_RS27955
uniprot id: D2PP46
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS03560
gene id: 479435:KFLA_RS03560
uniprot id: D2PYI9
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS18365
gene id: 479435:KFLA_RS18365
uniprot id: D2PNT5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

479435:KFLA RS32770
gene id: 479435:KFLA_RS32770
uniprot id: D2PZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

479435:KFLA RS33755
gene id: 479435:KFLA_RS33755
uniprot id: D2Q287
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

479435:KFLA RS18380
gene id: 479435:KFLA_RS18380
uniprot id: D2PNT8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06085
gene id: 479435:KFLA_RS06085
uniprot id: D2Q422
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS31605
gene id: 479435:KFLA_RS31605
uniprot id: D2PWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS20750
gene id: 479435:KFLA_RS20750
uniprot id: D2PTT9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS16740
gene id: 479435:KFLA_RS16740
uniprot id: D2PKW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS27430
gene id: 479435:KFLA_RS27430
uniprot id: D2PN56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

479435:KFLA RS20600
gene id: 479435:KFLA_RS20600
uniprot id: D2PSQ4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

479435:KFLA RS27250
gene id: 479435:KFLA_RS27250
uniprot id: D2PN21
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

479435:KFLA RS07900
gene id: 479435:KFLA_RS07900
uniprot id: D2PMF4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS37125
gene id: 479435:KFLA_RS37125
uniprot id: D2PVF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

479435:KFLA RS04775
gene id: 479435:KFLA_RS04775
uniprot id: D2Q187
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

479435:KFLA RS31760
gene id: 479435:KFLA_RS31760
uniprot id: D2PX12
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

479435:KFLA RS21670
gene id: 479435:KFLA_RS21670
uniprot id: D2PVB9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479435:KFLA RS27910
gene id: 479435:KFLA_RS27910
uniprot id: D2PP37
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

479435:KFLA RS23140
gene id: 479435:KFLA_RS23140
uniprot id: D2PZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS28395
gene id: 479435:KFLA_RS28395
uniprot id: D2PPD2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS04755
gene id: 479435:KFLA_RS04755
uniprot id: D2Q183
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

479435:KFLA RS22490
gene id: 479435:KFLA_RS22490
uniprot id: D2PXV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

479435:KFLA RS17430
gene id: 479435:KFLA_RS17430
uniprot id: D2PLY5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS02820
gene id: 479435:KFLA_RS02820
uniprot id: D2PW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS12030
gene id: 479435:KFLA_RS12030
uniprot id: D2PW53
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS31895
gene id: 479435:KFLA_RS31895
uniprot id: D2PX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS22715
gene id: 479435:KFLA_RS22715
uniprot id: D2PXZ8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS11945
gene id: 479435:KFLA_RS11945
uniprot id: D2PV22
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

479435:KFLA RS28355
gene id: 479435:KFLA_RS28355
uniprot id: D2PPC4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS08190
gene id: 479435:KFLA_RS08190
uniprot id: D2PML0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

479435:KFLA RS30380
gene id: 479435:KFLA_RS30380
uniprot id: D2PU73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

479435:KFLA RS16220
gene id: 479435:KFLA_RS16220
uniprot id: D2Q4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

479435:KFLA RS21735
gene id: 479435:KFLA_RS21735
uniprot id: D2PVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

479435:KFLA RS30420
gene id: 479435:KFLA_RS30420
uniprot id: D2PU81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

479435:KFLA RS14330
gene id: 479435:KFLA_RS14330
uniprot id: D2Q0G6
names: Similarity
messages: Belongs to the YggT family.

479435:KFLA RS33110
gene id: 479435:KFLA_RS33110
uniprot id: D2PZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

479435:KFLA RS00905
gene id: 479435:KFLA_RS00905
uniprot id: D2PRX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

479435:KFLA RS34865
gene id: 479435:KFLA_RS34865
uniprot id: D2Q3Y2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

479435:KFLA RS34020
gene id: 479435:KFLA_RS34020
uniprot id: D2Q2E0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS26460
gene id: 479435:KFLA_RS26460
uniprot id: D2PL98
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

479435:KFLA RS18840
gene id: 479435:KFLA_RS18840
uniprot id: D2PPS2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

479435:KFLA RS36200
gene id: 479435:KFLA_RS36200
uniprot id: D2PPL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

479435:KFLA RS09000
gene id: 479435:KFLA_RS09000
uniprot id: D2PPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS19265
gene id: 479435:KFLA_RS19265
uniprot id: D2PQ07
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

479435:KFLA RS00620
gene id: 479435:KFLA_RS00620
uniprot id: D2PRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS28625
gene id: 479435:KFLA_RS28625
uniprot id: D2PQ71
names: Similarity
messages: Belongs to the UDPGP type 1 family.

479435:KFLA RS13555
gene id: 479435:KFLA_RS13555
uniprot id: D2PZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS30295
gene id: 479435:KFLA_RS30295
uniprot id: D2PU56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

479435:KFLA RS25200
gene id: 479435:KFLA_RS25200
uniprot id: D2Q3H6
names: Similarity
messages: Belongs to the CobH/CbiC family.

479435:KFLA RS24000
gene id: 479435:KFLA_RS24000
uniprot id: D2Q0Q9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

479435:KFLA RS01225
gene id: 479435:KFLA_RS01225
uniprot id: D2PT58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS25375
gene id: 479435:KFLA_RS25375
uniprot id: D2Q3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

479435:KFLA RS28510
gene id: 479435:KFLA_RS28510
uniprot id: D2PQ49
names: Similarity
messages: Belongs to the fructosamine kinase family.

479435:KFLA RS08080
gene id: 479435:KFLA_RS08080
uniprot id: D2PMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS04740
gene id: 479435:KFLA_RS04740
uniprot id: D2Q180
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

479435:KFLA RS16255
gene id: 479435:KFLA_RS16255
uniprot id: D2Q4M5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

479435:KFLA RS21580
gene id: 479435:KFLA_RS21580
uniprot id: D2PVA1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

479435:KFLA RS18255
gene id: 479435:KFLA_RS18255
uniprot id: D2PNR3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

479435:KFLA RS09800
gene id: 479435:KFLA_RS09800
uniprot id: D2PQU2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS05190
gene id: 479435:KFLA_RS05190
uniprot id: D2Q1H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS22495
gene id: 479435:KFLA_RS22495
uniprot id: D2PXV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

479435:KFLA RS25860
gene id: 479435:KFLA_RS25860
uniprot id: D2Q4X6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS24285
gene id: 479435:KFLA_RS24285
uniprot id: D2Q1W9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

479435:KFLA RS23390
gene id: 479435:KFLA_RS23390
uniprot id: D2PZC9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479435:KFLA RS23320
gene id: 479435:KFLA_RS23320
uniprot id: D2PZB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

479435:KFLA RS10975
gene id: 479435:KFLA_RS10975
uniprot id: D2PTI8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS08340
gene id: 479435:KFLA_RS08340
uniprot id: D2PMP0
names: Similarity
messages: Belongs to the TPP enzyme family.

479435:KFLA RS31355
gene id: 479435:KFLA_RS31355
uniprot id: D2PVS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

479435:KFLA RS03340
gene id: 479435:KFLA_RS03340
uniprot id: D2PXE3
names: Similarity
messages: Belongs to the NodU/CmcH family.

479435:KFLA RS26935
gene id: 479435:KFLA_RS26935
uniprot id: D2PM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

479435:KFLA RS29615
gene id: 479435:KFLA_RS29615
uniprot id: D2PSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS13220
gene id: 479435:KFLA_RS13220
uniprot id: D2PXU7
names: Similarity
messages: Belongs to the CFA/CMAS family.

479435:KFLA RS15990
gene id: 479435:KFLA_RS15990
uniprot id: D2Q4H5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

479435:KFLA RS31420
gene id: 479435:KFLA_RS31420
uniprot id: D2PWU8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24075
gene id: 479435:KFLA_RS24075
uniprot id: D2Q0S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

479435:KFLA RS35030
gene id: 479435:KFLA_RS35030
uniprot id: D2Q526
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

479435:KFLA RS02680
gene id: 479435:KFLA_RS02680
uniprot id: D2PW01
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17150
gene id: 479435:KFLA_RS17150
uniprot id: D2PLS9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS19145
gene id: 479435:KFLA_RS19145
uniprot id: D2PPY3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

479435:KFLA RS18895
gene id: 479435:KFLA_RS18895
uniprot id: D2PPT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

479435:KFLA RS09755
gene id: 479435:KFLA_RS09755
uniprot id: D2PQT4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS22180
gene id: 479435:KFLA_RS22180
uniprot id: D2PWN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS31500
gene id: 479435:KFLA_RS31500
uniprot id: D2PWW3
names: Similarity
messages: Belongs to the aldose epimerase family.

479435:KFLA RS28870
gene id: 479435:KFLA_RS28870
uniprot id: D2PQB9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

479435:KFLA RS29170
gene id: 479435:KFLA_RS29170
uniprot id: D2PRG4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

479435:KFLA RS31915
gene id: 479435:KFLA_RS31915
uniprot id: D2PX42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

479435:KFLA RS19690
gene id: 479435:KFLA_RS19690
uniprot id: D2PR66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

479435:KFLA RS21730
gene id: 479435:KFLA_RS21730
uniprot id: D2PVD1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS27315
gene id: 479435:KFLA_RS27315
uniprot id: D2PN34
names: Similarity
messages: Belongs to the LOG family.

479435:KFLA RS31375
gene id: 479435:KFLA_RS31375
uniprot id: D2PVS9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS19220
gene id: 479435:KFLA_RS19220
uniprot id: D2PPZ8
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS29475
gene id: 479435:KFLA_RS29475
uniprot id: D2PRM4
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

479435:KFLA RS03025
gene id: 479435:KFLA_RS03025
uniprot id: D2PX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

479435:KFLA RS34255
gene id: 479435:KFLA_RS34255
uniprot id: D2Q2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

479435:KFLA RS26145
gene id: 479435:KFLA_RS26145
uniprot id: D2PL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS19390
gene id: 479435:KFLA_RS19390
uniprot id: D2PQ31
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

479435:KFLA RS36045
gene id: 479435:KFLA_RS36045
uniprot id: D2PSX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479435:KFLA RS13200
gene id: 479435:KFLA_RS13200
uniprot id: D2PXU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

479435:KFLA RS30275
gene id: 479435:KFLA_RS30275
uniprot id: D2PU52
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

479435:KFLA RS06295
gene id: 479435:KFLA_RS06295
uniprot id: D2Q465
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

479435:KFLA RS32255
gene id: 479435:KFLA_RS32255
uniprot id: D2PYC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

479435:KFLA RS17695
gene id: 479435:KFLA_RS17695
uniprot id: D2PMR8
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS35195
gene id: 479435:KFLA_RS35195
uniprot id: D2Q562
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

479435:KFLA RS06540
gene id: 479435:KFLA_RS06540
uniprot id: D2Q4B3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17160
gene id: 479435:KFLA_RS17160
uniprot id: D2PLT1
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

479435:KFLA RS25665
gene id: 479435:KFLA_RS25665
uniprot id: D2Q4T6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

479435:KFLA RS23850
gene id: 479435:KFLA_RS23850
uniprot id: D2Q0N0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

479435:KFLA RS30110
gene id: 479435:KFLA_RS30110
uniprot id: D2PT18
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

479435:KFLA RS16480
gene id: 479435:KFLA_RS16480
uniprot id: D2PKR8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

479435:KFLA RS28345
gene id: 479435:KFLA_RS28345
uniprot id: D2PPC2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS04200
gene id: 479435:KFLA_RS04200
uniprot id: D2PZV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS14145
gene id: 479435:KFLA_RS14145
uniprot id: D2Q0D0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

479435:KFLA RS11490
gene id: 479435:KFLA_RS11490
uniprot id: D2PUT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

479435:KFLA RS33620
gene id: 479435:KFLA_RS33620
uniprot id: D2Q155
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

479435:KFLA RS09360
gene id: 479435:KFLA_RS09360
uniprot id: D2PPM5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS08460
gene id: 479435:KFLA_RS08460
uniprot id: D2PNF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479435:KFLA RS07910
gene id: 479435:KFLA_RS07910
uniprot id: D2PMF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

479435:KFLA RS31850
gene id: 479435:KFLA_RS31850
uniprot id: D2PX29
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

479435:KFLA RS26485
gene id: 479435:KFLA_RS26485
uniprot id: D2PLA3
names: Similarity
messages: Belongs to the IucA/IucC family.

479435:KFLA RS15605
gene id: 479435:KFLA_RS15605
uniprot id: D2Q388
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS08035
gene id: 479435:KFLA_RS08035
uniprot id: D2PMI0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS27340
gene id: 479435:KFLA_RS27340
uniprot id: D2PN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS27765
gene id: 479435:KFLA_RS27765
uniprot id: D2PNC0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

479435:KFLA RS17010
gene id: 479435:KFLA_RS17010
uniprot id: D2PLQ1
names: Similarity
messages: Belongs to the DDAH family.

479435:KFLA RS01260
gene id: 479435:KFLA_RS01260
uniprot id: D2PT65
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS32120
gene id: 479435:KFLA_RS32120
uniprot id: D2PY95
names: Similarity
messages: Belongs to the peptidase S1 family.

479435:KFLA RS13870
gene id: 479435:KFLA_RS13870
uniprot id: D2Q075
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS16170
gene id: 479435:KFLA_RS16170
uniprot id: D2Q4K8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

479435:KFLA RS15160
gene id: 479435:KFLA_RS15160
uniprot id: D2Q300
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS27800
gene id: 479435:KFLA_RS27800
uniprot id: D2PNC7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23590
gene id: 479435:KFLA_RS23590
uniprot id: D2PZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

479435:KFLA RS07895
gene id: 479435:KFLA_RS07895
uniprot id: D2PMF3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS13950
gene id: 479435:KFLA_RS13950
uniprot id: D2Q091
names: Similarity
messages: Belongs to the arsA ATPase family.

479435:KFLA RS25975
gene id: 479435:KFLA_RS25975
uniprot id: D2Q4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS20640
gene id: 479435:KFLA_RS20640
uniprot id: D2PSR2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS31245
gene id: 479435:KFLA_RS31245
uniprot id: D2PVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

479435:KFLA RS23745
gene id: 479435:KFLA_RS23745
uniprot id: D2Q0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

479435:KFLA RS11275
gene id: 479435:KFLA_RS11275
uniprot id: D2PTP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

479435:KFLA RS00910
gene id: 479435:KFLA_RS00910
uniprot id: D2PRY0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS30010
gene id: 479435:KFLA_RS30010
uniprot id: D2PSZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS08040
gene id: 479435:KFLA_RS08040
uniprot id: D2PMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS00695
gene id: 479435:KFLA_RS00695
uniprot id: D2PRT7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479435:KFLA RS20480
gene id: 479435:KFLA_RS20480
uniprot id: D2PSN0
names: Similarity
messages: Belongs to the cytochrome P450 family.

479435:KFLA RS26150
gene id: 479435:KFLA_RS26150
uniprot id: D2PL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS34480
gene id: 479435:KFLA_RS34480
uniprot id: D2Q3Q6
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS18135
gene id: 479435:KFLA_RS18135
uniprot id: D2PN05
names: Similarity
messages: Belongs to the universal stress protein A family.

479435:KFLA RS27645
gene id: 479435:KFLA_RS27645
uniprot id: D2PN97
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS15710
gene id: 479435:KFLA_RS15710
uniprot id: D2Q4C0
names: Similarity
messages: Belongs to the UPF0749 family.

479435:KFLA RS08955
gene id: 479435:KFLA_RS08955
uniprot id: D2PPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS18120
gene id: 479435:KFLA_RS18120
uniprot id: D2PN02
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

479435:KFLA RS23725
gene id: 479435:KFLA_RS23725
uniprot id: D2Q0K5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS26645
gene id: 479435:KFLA_RS26645
uniprot id: D2PM22
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS20810
gene id: 479435:KFLA_RS20810
uniprot id: D2PTV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS06265
gene id: 479435:KFLA_RS06265
uniprot id: D2Q458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS19645
gene id: 479435:KFLA_RS19645
uniprot id: D2PR57
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS14910
gene id: 479435:KFLA_RS14910
uniprot id: D2Q1T6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS34045
gene id: 479435:KFLA_RS34045
uniprot id: D2Q2E5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479435:KFLA RS17415
gene id: 479435:KFLA_RS17415
uniprot id: D2PLY2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS10505
gene id: 479435:KFLA_RS10505
uniprot id: D2PS85
names: Similarity
messages: Belongs to the ketopantoate reductase family.

479435:KFLA RS04660
gene id: 479435:KFLA_RS04660
uniprot id: D2Q054
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS31115
gene id: 479435:KFLA_RS31115
uniprot id: D2PVM8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

479435:KFLA RS25590
gene id: 479435:KFLA_RS25590
uniprot id: D2Q4S1
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

479435:KFLA RS19635
gene id: 479435:KFLA_RS19635
uniprot id: D2PR55
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS29320
gene id: 479435:KFLA_RS29320
uniprot id: D2PRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS26590
gene id: 479435:KFLA_RS26590
uniprot id: D2PLC4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS16520
gene id: 479435:KFLA_RS16520
uniprot id: D2PKS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

479435:KFLA RS34820
gene id: 479435:KFLA_RS34820
uniprot id: D2Q3X3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30490
gene id: 479435:KFLA_RS30490
uniprot id: D2PU94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

479435:KFLA RS20980
gene id: 479435:KFLA_RS20980
uniprot id: D2PTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS27360
gene id: 479435:KFLA_RS27360
uniprot id: D2PN42
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

479435:KFLA RS15045
gene id: 479435:KFLA_RS15045
uniprot id: D2Q1W3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: Belongs to the fatty acyl-CoA reductase family.

479435:KFLA RS31805
gene id: 479435:KFLA_RS31805
uniprot id: D2PX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS06740
gene id: 479435:KFLA_RS06740
uniprot id: D2PKF5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15165
gene id: 479435:KFLA_RS15165
uniprot id: D2Q301
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

479435:KFLA RS09595
gene id: 479435:KFLA_RS09595
uniprot id: D2PQQ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

479435:KFLA RS00455
gene id: 479435:KFLA_RS00455
uniprot id: D2PQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS34775
gene id: 479435:KFLA_RS34775
uniprot id: D2Q3W4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

479435:KFLA RS00185
gene id: 479435:KFLA_RS00185
uniprot id: D2PQH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

479435:KFLA RS31790
gene id: 479435:KFLA_RS31790
uniprot id: D2PX18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

479435:KFLA RS11780
gene id: 479435:KFLA_RS11780
uniprot id: D2PUY9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

479435:KFLA RS35085
gene id: 479435:KFLA_RS35085
uniprot id: D2Q537
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS34785
gene id: 479435:KFLA_RS34785
uniprot id: D2Q3W6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS12520
gene id: 479435:KFLA_RS12520
uniprot id: D2PWF0
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS25315
gene id: 479435:KFLA_RS25315
uniprot id: D2Q3J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS32200
gene id: 479435:KFLA_RS32200
uniprot id: D2PYB1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18845
gene id: 479435:KFLA_RS18845
uniprot id: D2PPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS11495
gene id: 479435:KFLA_RS11495
uniprot id: D2PUT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS26120
gene id: 479435:KFLA_RS26120
uniprot id: D2PL27
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

479435:KFLA RS34085
gene id: 479435:KFLA_RS34085
uniprot id: D2Q2F2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS17680
gene id: 479435:KFLA_RS17680
uniprot id: D2PMR5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS25530
gene id: 479435:KFLA_RS25530
uniprot id: D2Q4R0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

479435:KFLA RS26775
gene id: 479435:KFLA_RS26775
uniprot id: D2PM48
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS25165
gene id: 479435:KFLA_RS25165
uniprot id: D2Q3G9
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS05900
gene id: 479435:KFLA_RS05900
uniprot id: D2Q2W8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

479435:KFLA RS18730
gene id: 479435:KFLA_RS18730
uniprot id: D2PP07
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

479435:KFLA RS08060
gene id: 479435:KFLA_RS08060
uniprot id: D2PMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

479435:KFLA RS00345
gene id: 479435:KFLA_RS00345
uniprot id: D2PQL0
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS22175
gene id: 479435:KFLA_RS22175
uniprot id: D2PWN0
names: Similarity
messages: Belongs to the arginase family.

479435:KFLA RS01080
gene id: 479435:KFLA_RS01080
uniprot id: D2PS15
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS30320
gene id: 479435:KFLA_RS30320
uniprot id: D2PU61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

479435:KFLA RS23355
gene id: 479435:KFLA_RS23355
uniprot id: D2PZC2
names: Similarity
messages: Belongs to the peptidase M1 family.

479435:KFLA RS26010
gene id: 479435:KFLA_RS26010
uniprot id: D2Q505
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24845
gene id: 479435:KFLA_RS24845
uniprot id: D2Q283
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS00290
gene id: 479435:KFLA_RS00290
uniprot id: D2PQK0
names: Similarity
messages: Belongs to the UPF0749 family.

479435:KFLA RS00740
gene id: 479435:KFLA_RS00740
uniprot id: D2PRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

479435:KFLA RS19600
gene id: 479435:KFLA_RS19600
uniprot id: D2PR48
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

479435:KFLA RS18960
gene id: 479435:KFLA_RS18960
uniprot id: D2PPU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS11485
gene id: 479435:KFLA_RS11485
uniprot id: D2PUT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

479435:KFLA RS09470
gene id: 479435:KFLA_RS09470
uniprot id: D2PPP7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS10365
gene id: 479435:KFLA_RS10365
uniprot id: D2PS58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS38385
gene id: 479435:KFLA_RS38385
uniprot id: D2PSK6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

479435:KFLA RS13035
gene id: 479435:KFLA_RS13035
uniprot id: D2PXR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

479435:KFLA RS13320
gene id: 479435:KFLA_RS13320
uniprot id: D2PYW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

479435:KFLA RS11450
gene id: 479435:KFLA_RS11450
uniprot id: D2PUS5
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS17050
gene id: 479435:KFLA_RS17050
uniprot id: D2PLQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

479435:KFLA RS15810
gene id: 479435:KFLA_RS15810
uniprot id: D2Q4E0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS11160
gene id: 479435:KFLA_RS11160
uniprot id: D2PTM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane

479435:KFLA RS23325
gene id: 479435:KFLA_RS23325
uniprot id: D2PZB6
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS15745
gene id: 479435:KFLA_RS15745
uniprot id: D2Q4C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

479435:KFLA RS25920
gene id: 479435:KFLA_RS25920
uniprot id: D2Q4Y7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

479435:KFLA RS02045
gene id: 479435:KFLA_RS02045
uniprot id: D2PUL5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

479435:KFLA RS17610
gene id: 479435:KFLA_RS17610
uniprot id: D2PMQ1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

479435:KFLA RS32190
gene id: 479435:KFLA_RS32190
uniprot id: D2PYA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS24525
gene id: 479435:KFLA_RS24525
uniprot id: D2Q217
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

479435:KFLA RS28295
gene id: 479435:KFLA_RS28295
uniprot id: D2PPB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

479435:KFLA RS26475
gene id: 479435:KFLA_RS26475
uniprot id: D2PLA1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS12695
gene id: 479435:KFLA_RS12695
uniprot id: D2PXJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

479435:KFLA RS34835
gene id: 479435:KFLA_RS34835
uniprot id: D2Q3X6
names: Similarity
messages: Belongs to the FemABX family.

479435:KFLA RS11925
gene id: 479435:KFLA_RS11925
uniprot id: D2PV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

479435:KFLA RS25910
gene id: 479435:KFLA_RS25910
uniprot id: D2Q4Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

479435:KFLA RS05405
gene id: 479435:KFLA_RS05405
uniprot id: D2Q2M0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS34335
gene id: 479435:KFLA_RS34335
uniprot id: D2Q2K2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23975
gene id: 479435:KFLA_RS23975
uniprot id: D2Q0Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

479435:KFLA RS33010
gene id: 479435:KFLA_RS33010
uniprot id: D2PZS0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479435:KFLA RS07450
gene id: 479435:KFLA_RS07450
uniprot id: D2PLH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS10345
gene id: 479435:KFLA_RS10345
uniprot id: D2PS54
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

479435:KFLA RS34885
gene id: 479435:KFLA_RS34885
uniprot id: D2Q3Y6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

479435:KFLA RS26800
gene id: 479435:KFLA_RS26800
uniprot id: D2PM53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

479435:KFLA RS33175
gene id: 479435:KFLA_RS33175
uniprot id: D2Q0W8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

479435:KFLA RS06070
gene id: 479435:KFLA_RS06070
uniprot id: D2Q419
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS29835
gene id: 479435:KFLA_RS29835
uniprot id: D2PSW3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS20495
gene id: 479435:KFLA_RS20495
uniprot id: D2PSN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS31105
gene id: 479435:KFLA_RS31105
uniprot id: D2PVM6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS27155
gene id: 479435:KFLA_RS27155
uniprot id: D2PMB8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

479435:KFLA RS17700
gene id: 479435:KFLA_RS17700
uniprot id: D2PMR9
names: Similarity
messages: Belongs to the peptidase M4 family.

479435:KFLA RS04455
gene id: 479435:KFLA_RS04455
uniprot id: D2Q011
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

479435:KFLA RS32020
gene id: 479435:KFLA_RS32020
uniprot id: D2PY75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

479435:KFLA RS38630
gene id: 479435:KFLA_RS38630
uniprot id: D2PVZ7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

479435:KFLA RS27925
gene id: 479435:KFLA_RS27925
uniprot id: D2PP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS23470
gene id: 479435:KFLA_RS23470
uniprot id: D2PZE5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

479435:KFLA RS23375
gene id: 479435:KFLA_RS23375
uniprot id: D2PZC6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

479435:KFLA RS13435
gene id: 479435:KFLA_RS13435
uniprot id: D2PYY6
names: Similarity
messages: Belongs to the PspA/IM30 family.

479435:KFLA RS14625
gene id: 479435:KFLA_RS14625
uniprot id: D2Q1M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

479435:KFLA RS00980
gene id: 479435:KFLA_RS00980
uniprot id: D2PRZ6
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

479435:KFLA RS19260
gene id: 479435:KFLA_RS19260
uniprot id: D2PQ06
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS26690
gene id: 479435:KFLA_RS26690
uniprot id: D2PM31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS13305
gene id: 479435:KFLA_RS13305
uniprot id: D2PYW1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

479435:KFLA RS23680
gene id: 479435:KFLA_RS23680
uniprot id: D2Q0J6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

479435:KFLA RS29265
gene id: 479435:KFLA_RS29265
uniprot id: D2PRI2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

479435:KFLA RS05920
gene id: 479435:KFLA_RS05920
uniprot id: D2Q2X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

479435:KFLA RS32915
gene id: 479435:KFLA_RS32915
uniprot id: D2PZQ1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

479435:KFLA RS03090
gene id: 479435:KFLA_RS03090
uniprot id: D2PX94
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

479435:KFLA RS30265
gene id: 479435:KFLA_RS30265
uniprot id: D2PU50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS29140
gene id: 479435:KFLA_RS29140
uniprot id: D2PRF8
names: Similarity
messages: Belongs to the DNA photolyase family.

479435:KFLA RS01145
gene id: 479435:KFLA_RS01145
uniprot id: D2PT41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS22135
gene id: 479435:KFLA_RS22135
uniprot id: D2PWM2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17330
gene id: 479435:KFLA_RS17330
uniprot id: D2PLW5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS34225
gene id: 479435:KFLA_RS34225
uniprot id: D2Q2I0
names: Similarity
messages: Belongs to the peptidase S1C family.

479435:KFLA RS06220
gene id: 479435:KFLA_RS06220
uniprot id: D2Q449
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

479435:KFLA RS23345
gene id: 479435:KFLA_RS23345
uniprot id: D2PZC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

479435:KFLA RS16210
gene id: 479435:KFLA_RS16210
uniprot id: D2Q4L6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS23735
gene id: 479435:KFLA_RS23735
uniprot id: D2Q0K7
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS21570
gene id: 479435:KFLA_RS21570
uniprot id: D2PV99
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

479435:KFLA RS25925
gene id: 479435:KFLA_RS25925
uniprot id: D2Q4Y8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS32015
gene id: 479435:KFLA_RS32015
uniprot id: D2PY74
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

479435:KFLA RS34185
gene id: 479435:KFLA_RS34185
uniprot id: D2Q2H1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

479435:KFLA RS01330
gene id: 479435:KFLA_RS01330
uniprot id: D2PT79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

479435:KFLA RS18370
gene id: 479435:KFLA_RS18370
uniprot id: D2PNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS24135
gene id: 479435:KFLA_RS24135
uniprot id: D2Q0T4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

479435:KFLA RS30750
gene id: 479435:KFLA_RS30750
uniprot id: D2PUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

479435:KFLA RS27465
gene id: 479435:KFLA_RS27465
uniprot id: D2PN62
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

479435:KFLA RS07070
gene id: 479435:KFLA_RS07070
uniprot id: D2PKM1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06455
gene id: 479435:KFLA_RS06455
uniprot id: D2Q497
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS23560
gene id: 479435:KFLA_RS23560
uniprot id: D2PZG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

479435:KFLA RS22960
gene id: 479435:KFLA_RS22960
uniprot id: D2PY49
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS01995
gene id: 479435:KFLA_RS01995
uniprot id: D2PUK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

479435:KFLA RS00015
gene id: 479435:KFLA_RS00015
uniprot id: D2PQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

479435:KFLA RS23970
gene id: 479435:KFLA_RS23970
uniprot id: D2Q0Q4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS26100
gene id: 479435:KFLA_RS26100
uniprot id: D2PL23
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

479435:KFLA RS26975
gene id: 479435:KFLA_RS26975
uniprot id: D2PM83
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS13685
gene id: 479435:KFLA_RS13685
uniprot id: D2PZ36
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS23795
gene id: 479435:KFLA_RS23795
uniprot id: D2Q0L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

479435:KFLA RS01440
gene id: 479435:KFLA_RS01440
uniprot id: D2PT98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

479435:KFLA RS12985
gene id: 479435:KFLA_RS12985
uniprot id: D2PXQ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS25185
gene id: 479435:KFLA_RS25185
uniprot id: D2Q3H3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

479435:KFLA RS30425
gene id: 479435:KFLA_RS30425
uniprot id: D2PU82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS23630
gene id: 479435:KFLA_RS23630
uniprot id: D2PZH7
names: Similarity
messages: Belongs to the peptidase S1 family.

479435:KFLA RS13275
gene id: 479435:KFLA_RS13275
uniprot id: D2PYV7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

479435:KFLA RS20315
gene id: 479435:KFLA_RS20315
uniprot id: D2PSJ6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS04025
gene id: 479435:KFLA_RS04025
uniprot id: D2PYS9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30255
gene id: 479435:KFLA_RS30255
uniprot id: D2PU48
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS00820
gene id: 479435:KFLA_RS00820
uniprot id: D2PRW3
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS32135
gene id: 479435:KFLA_RS32135
uniprot id: D2PY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

479435:KFLA RS16845
gene id: 479435:KFLA_RS16845
uniprot id: D2PKY4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18260
gene id: 479435:KFLA_RS18260
uniprot id: D2PNR4
names: Similarity
messages: Belongs to the UPF0098 family.

479435:KFLA RS00840
gene id: 479435:KFLA_RS00840
uniprot id: D2PRW7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25300
gene id: 479435:KFLA_RS25300
uniprot id: D2Q3J6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

479435:KFLA RS21840
gene id: 479435:KFLA_RS21840
uniprot id: D2PVF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

479435:KFLA RS00755
gene id: 479435:KFLA_RS00755
uniprot id: D2PRU9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS23275
gene id: 479435:KFLA_RS23275
uniprot id: D2PZA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

479435:KFLA RS07705
gene id: 479435:KFLA_RS07705
uniprot id: D2PLN1
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS11985
gene id: 479435:KFLA_RS11985
uniprot id: D2PV30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

479435:KFLA RS30645
gene id: 479435:KFLA_RS30645
uniprot id: D2PUC4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS16660
gene id: 479435:KFLA_RS16660
uniprot id: D2PKU7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS05095
gene id: 479435:KFLA_RS05095
uniprot id: D2Q1F2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS03720
gene id: 479435:KFLA_RS03720
uniprot id: D2PYL9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS34300
gene id: 479435:KFLA_RS34300
uniprot id: D2Q2J5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS17825
gene id: 479435:KFLA_RS17825
uniprot id: D2PMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS29405
gene id: 479435:KFLA_RS29405
uniprot id: D2PRL0
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

479435:KFLA RS15040
gene id: 479435:KFLA_RS15040
uniprot id: D2Q1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

479435:KFLA RS24150
gene id: 479435:KFLA_RS24150
uniprot id: D2Q0T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS08580
gene id: 479435:KFLA_RS08580
uniprot id: D2PNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

479435:KFLA RS26315
gene id: 479435:KFLA_RS26315
uniprot id: D2PL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

479435:KFLA RS24145
gene id: 479435:KFLA_RS24145
uniprot id: D2Q0T6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS06905
gene id: 479435:KFLA_RS06905
uniprot id: D2PKI7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

479435:KFLA RS16505
gene id: 479435:KFLA_RS16505
uniprot id: D2PKS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS11375
gene id: 479435:KFLA_RS11375
uniprot id: D2PTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

479435:KFLA RS02315
gene id: 479435:KFLA_RS02315
uniprot id: D2PUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

479435:KFLA RS05440
gene id: 479435:KFLA_RS05440
uniprot id: D2Q2M7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

479435:KFLA RS10250
gene id: 479435:KFLA_RS10250
uniprot id: D2PS36
names: Similarity
messages: Belongs to the SAICAR synthetase family.

479435:KFLA RS29290
gene id: 479435:KFLA_RS29290
uniprot id: D2PRI7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS28630
gene id: 479435:KFLA_RS28630
uniprot id: D2PQ72
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

479435:KFLA RS05730
gene id: 479435:KFLA_RS05730
uniprot id: D2Q2T5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS12960
gene id: 479435:KFLA_RS12960
uniprot id: D2PXP7
names: Similarity
messages: Belongs to the glutamine synthetase family.

479435:KFLA RS13345
gene id: 479435:KFLA_RS13345
uniprot id: D2PYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS06270
gene id: 479435:KFLA_RS06270
uniprot id: D2Q460
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

479435:KFLA RS12585
gene id: 479435:KFLA_RS12585
uniprot id: D2PWG3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17310
gene id: 479435:KFLA_RS17310
uniprot id: D2PLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS21540
gene id: 479435:KFLA_RS21540
uniprot id: D2PV93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

479435:KFLA RS02290
gene id: 479435:KFLA_RS02290
uniprot id: D2PUR3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29330
gene id: 479435:KFLA_RS29330
uniprot id: D2PRJ5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

479435:KFLA RS03850
gene id: 479435:KFLA_RS03850
uniprot id: D2PYP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

479435:KFLA RS18585
gene id: 479435:KFLA_RS18585
uniprot id: D2PNX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

479435:KFLA RS30410
gene id: 479435:KFLA_RS30410
uniprot id: D2PU79
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

479435:KFLA RS25005
gene id: 479435:KFLA_RS25005
uniprot id: D2Q3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

479435:KFLA RS14490
gene id: 479435:KFLA_RS14490
uniprot id: D2Q1K2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25720
gene id: 479435:KFLA_RS25720
uniprot id: D2Q4U8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS12095
gene id: 479435:KFLA_RS12095
uniprot id: D2PW66
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

479435:KFLA RS23805
gene id: 479435:KFLA_RS23805
uniprot id: D2Q0M1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

479435:KFLA RS28495
gene id: 479435:KFLA_RS28495
uniprot id: D2PQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS25095
gene id: 479435:KFLA_RS25095
uniprot id: D2Q3F6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS13445
gene id: 479435:KFLA_RS13445
uniprot id: D2PYY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

479435:KFLA RS22330
gene id: 479435:KFLA_RS22330
uniprot id: D2PWR0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS12390
gene id: 479435:KFLA_RS12390
uniprot id: D2PWC6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479435:KFLA RS28690
gene id: 479435:KFLA_RS28690
uniprot id: D2PQ83
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS28365
gene id: 479435:KFLA_RS28365
uniprot id: D2PPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

479435:KFLA RS34805
gene id: 479435:KFLA_RS34805
uniprot id: D2Q3X0
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

479435:KFLA RS29505
gene id: 479435:KFLA_RS29505
uniprot id: D2PRN0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30650
gene id: 479435:KFLA_RS30650
uniprot id: D2PUC5
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS11155
gene id: 479435:KFLA_RS11155
uniprot id: D2PTM4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS19870
gene id: 479435:KFLA_RS19870
uniprot id: D2PRA1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS04855
gene id: 479435:KFLA_RS04855
uniprot id: D2Q1A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS06435
gene id: 479435:KFLA_RS06435
uniprot id: D2Q493
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS34625
gene id: 479435:KFLA_RS34625
uniprot id: D2Q3T4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09860
gene id: 479435:KFLA_RS09860
uniprot id: D2PQV4
names: Similarity
messages: Belongs to the glycosyl hydrolase.

479435:KFLA RS11845
gene id: 479435:KFLA_RS11845
uniprot id: D2PV02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

479435:KFLA RS05610
gene id: 479435:KFLA_RS05610
uniprot id: D2Q2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479435:KFLA RS14455
gene id: 479435:KFLA_RS14455
uniprot id: D2Q0J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

479435:KFLA RS04260
gene id: 479435:KFLA_RS04260
uniprot id: D2PZX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS33830
gene id: 479435:KFLA_RS33830
uniprot id: D2Q2A2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS21650
gene id: 479435:KFLA_RS21650
uniprot id: D2PVB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS16630
gene id: 479435:KFLA_RS16630
uniprot id: D2PKU4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS06725
gene id: 479435:KFLA_RS06725
uniprot id: D2PKF2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

479435:KFLA RS26180
gene id: 479435:KFLA_RS26180
uniprot id: D2PL39
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

479435:KFLA RS35015
gene id: 479435:KFLA_RS35015
uniprot id: D2Q523
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS17925
gene id: 479435:KFLA_RS17925
uniprot id: D2PMW5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS24060
gene id: 479435:KFLA_RS24060
uniprot id: D2Q0S1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

479435:KFLA RS04895
gene id: 479435:KFLA_RS04895
uniprot id: D2Q1B2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21515
gene id: 479435:KFLA_RS21515
uniprot id: D2PV88
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

479435:KFLA RS09985
gene id: 479435:KFLA_RS09985
uniprot id: D2PQX9
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

479435:KFLA RS13250
gene id: 479435:KFLA_RS13250
uniprot id: D2PYV1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS14875
gene id: 479435:KFLA_RS14875
uniprot id: D2Q1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

479435:KFLA RS25685
gene id: 479435:KFLA_RS25685
uniprot id: D2Q4U0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

479435:KFLA RS25455
gene id: 479435:KFLA_RS25455
uniprot id: D2Q3M7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

479435:KFLA RS25760
gene id: 479435:KFLA_RS25760
uniprot id: D2Q4V6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

479435:KFLA RS03150
gene id: 479435:KFLA_RS03150
uniprot id: D2PXA6
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS15195
gene id: 479435:KFLA_RS15195
uniprot id: D2Q307
names: Similarity
messages: Belongs to the SCO1/2 family.

479435:KFLA RS24580
gene id: 479435:KFLA_RS24580
uniprot id: D2Q229
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS16460
gene id: 479435:KFLA_RS16460
uniprot id: D2PKR4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

479435:KFLA RS26825
gene id: 479435:KFLA_RS26825
uniprot id: D2PM57
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS11855
gene id: 479435:KFLA_RS11855
uniprot id: D2PV04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS05015
gene id: 479435:KFLA_RS05015
uniprot id: D2Q1D6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

479435:KFLA RS30800
gene id: 479435:KFLA_RS30800
uniprot id: D2PVG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

479435:KFLA RS31230
gene id: 479435:KFLA_RS31230
uniprot id: D2PVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS10560
gene id: 479435:KFLA_RS10560
uniprot id: D2PS96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

479435:KFLA RS10480
gene id: 479435:KFLA_RS10480
uniprot id: D2PS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS03300
gene id: 479435:KFLA_RS03300
uniprot id: D2PXD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS21835
gene id: 479435:KFLA_RS21835
uniprot id: D2PVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS04290
gene id: 479435:KFLA_RS04290
uniprot id: D2PZX7
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

479435:KFLA RS01595
gene id: 479435:KFLA_RS01595
uniprot id: D2PTC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS01825
gene id: 479435:KFLA_RS01825
uniprot id: D2PUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS27920
gene id: 479435:KFLA_RS27920
uniprot id: D2PP39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

479435:KFLA RS14655
gene id: 479435:KFLA_RS14655
uniprot id: D2Q1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS32455
gene id: 479435:KFLA_RS32455
uniprot id: D2PYG3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

479435:KFLA RS01820
gene id: 479435:KFLA_RS01820
uniprot id: D2PUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS22095
gene id: 479435:KFLA_RS22095
uniprot id: D2PWL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

479435:KFLA RS02005
gene id: 479435:KFLA_RS02005
uniprot id: D2PUK7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS06185
gene id: 479435:KFLA_RS06185
uniprot id: D2Q442
names: Similarity
messages: Belongs to the peptidase S51 family.

479435:KFLA RS07710
gene id: 479435:KFLA_RS07710
uniprot id: D2PLN2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS27295
gene id: 479435:KFLA_RS27295
uniprot id: D2PN30
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479435:KFLA RS03470
gene id: 479435:KFLA_RS03470
uniprot id: D2PXG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS32395
gene id: 479435:KFLA_RS32395
uniprot id: D2PYF1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS34005
gene id: 479435:KFLA_RS34005
uniprot id: D2Q2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS16780
gene id: 479435:KFLA_RS16780
uniprot id: D2PKX1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

479435:KFLA RS32155
gene id: 479435:KFLA_RS32155
uniprot id: D2PYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

479435:KFLA RS34355
gene id: 479435:KFLA_RS34355
uniprot id: D2Q3N1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS22120
gene id: 479435:KFLA_RS22120
uniprot id: D2PWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479435:KFLA RS28880
gene id: 479435:KFLA_RS28880
uniprot id: D2PQC1
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS17790
gene id: 479435:KFLA_RS17790
uniprot id: D2PMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS33710
gene id: 479435:KFLA_RS33710
uniprot id: D2Q173
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

479435:KFLA RS08925
gene id: 479435:KFLA_RS08925
uniprot id: D2PPE0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS30330
gene id: 479435:KFLA_RS30330
uniprot id: D2PU63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

479435:KFLA RS16025
gene id: 479435:KFLA_RS16025
uniprot id: D2Q4I2
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

479435:KFLA RS10950
gene id: 479435:KFLA_RS10950
uniprot id: D2PTI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479435:KFLA RS24450
gene id: 479435:KFLA_RS24450
uniprot id: D2Q202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS13660
gene id: 479435:KFLA_RS13660
uniprot id: D2PZ31
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

479435:KFLA RS30620
gene id: 479435:KFLA_RS30620
uniprot id: D2PUC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

479435:KFLA RS14465
gene id: 479435:KFLA_RS14465
uniprot id: D2Q1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

479435:KFLA RS23405
gene id: 479435:KFLA_RS23405
uniprot id: D2PZD2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS25205
gene id: 479435:KFLA_RS25205
uniprot id: D2Q3H7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

479435:KFLA RS23825
gene id: 479435:KFLA_RS23825
uniprot id: D2Q0M5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

479435:KFLA RS09050
gene id: 479435:KFLA_RS09050
uniprot id: D2PPG5
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

479435:KFLA RS31025
gene id: 479435:KFLA_RS31025
uniprot id: D2PVK8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

479435:KFLA RS34590
gene id: 479435:KFLA_RS34590
uniprot id: D2Q3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

479435:KFLA RS07480
gene id: 479435:KFLA_RS07480
uniprot id: D2PLI5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS15415
gene id: 479435:KFLA_RS15415
uniprot id: D2Q351
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

479435:KFLA RS28615
gene id: 479435:KFLA_RS28615
uniprot id: D2PQ69
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

479435:KFLA RS08415
gene id: 479435:KFLA_RS08415
uniprot id: D2PNE8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS13075
gene id: 479435:KFLA_RS13075
uniprot id: D2PXS0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

479435:KFLA RS25010
gene id: 479435:KFLA_RS25010
uniprot id: D2Q3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

479435:KFLA RS06300
gene id: 479435:KFLA_RS06300
uniprot id: D2Q466
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

479435:KFLA RS25115
gene id: 479435:KFLA_RS25115
uniprot id: D2Q3G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

479435:KFLA RS30180
gene id: 479435:KFLA_RS30180
uniprot id: D2PT32
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

479435:KFLA RS01615
gene id: 479435:KFLA_RS01615
uniprot id: D2PTD3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

479435:KFLA RS26395
gene id: 479435:KFLA_RS26395
uniprot id: D2PL83
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

479435:KFLA RS13690
gene id: 479435:KFLA_RS13690
uniprot id: D2PZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

479435:KFLA RS12135
gene id: 479435:KFLA_RS12135
uniprot id: D2PW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS33545
gene id: 479435:KFLA_RS33545
uniprot id: D2Q141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS31645
gene id: 479435:KFLA_RS31645
uniprot id: D2PWZ1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS01190
gene id: 479435:KFLA_RS01190
uniprot id: D2PT50
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS12890
gene id: 479435:KFLA_RS12890
uniprot id: D2PXN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

479435:KFLA RS09030
gene id: 479435:KFLA_RS09030
uniprot id: D2PPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS15835
gene id: 479435:KFLA_RS15835
uniprot id: D2Q4E5
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

479435:KFLA RS24495
gene id: 479435:KFLA_RS24495
uniprot id: D2Q211
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

479435:KFLA RS17735
gene id: 479435:KFLA_RS17735
uniprot id: D2PMS6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

479435:KFLA RS21220
gene id: 479435:KFLA_RS21220
uniprot id: D2PU27
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS22645
gene id: 479435:KFLA_RS22645
uniprot id: D2PXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS17575
gene id: 479435:KFLA_RS17575
uniprot id: D2PMP4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

479435:KFLA RS20775
gene id: 479435:KFLA_RS20775
uniprot id: D2PTU4
names: Similarity
messages: Belongs to the KduI family.

479435:KFLA RS17315
gene id: 479435:KFLA_RS17315
uniprot id: D2PLW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS12000
gene id: 479435:KFLA_RS12000
uniprot id: D2PV33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS05360
gene id: 479435:KFLA_RS05360
uniprot id: D2Q2L1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

479435:KFLA RS28315
gene id: 479435:KFLA_RS28315
uniprot id: D2PPB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

479435:KFLA RS21690
gene id: 479435:KFLA_RS21690
uniprot id: D2PVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

479435:KFLA RS33095
gene id: 479435:KFLA_RS33095
uniprot id: D2PZT7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS29740
gene id: 479435:KFLA_RS29740
uniprot id: D2PSU3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS13300
gene id: 479435:KFLA_RS13300
uniprot id: D2PYW0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

479435:KFLA RS15020
gene id: 479435:KFLA_RS15020
uniprot id: D2Q1V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS06105
gene id: 479435:KFLA_RS06105
uniprot id: D2Q426
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21275
gene id: 479435:KFLA_RS21275
uniprot id: D2PV41
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS02600
gene id: 479435:KFLA_RS02600
uniprot id: D2PVY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS24195
gene id: 479435:KFLA_RS24195
uniprot id: D2Q0U6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS30280
gene id: 479435:KFLA_RS30280
uniprot id: D2PU53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

479435:KFLA RS23585
gene id: 479435:KFLA_RS23585
uniprot id: D2PZG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

479435:KFLA RS22445
gene id: 479435:KFLA_RS22445
uniprot id: D2PWT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS24670
gene id: 479435:KFLA_RS24670
uniprot id: D2Q247
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

479435:KFLA RS23685
gene id: 479435:KFLA_RS23685
uniprot id: D2Q0J7
names: Similarity
messages: Belongs to the P(II) protein family.

479435:KFLA RS00265
gene id: 479435:KFLA_RS00265
uniprot id: D2PQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS05230
gene id: 479435:KFLA_RS05230
uniprot id: D2Q1H9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS04250
gene id: 479435:KFLA_RS04250
uniprot id: D2PZW9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS27260
gene id: 479435:KFLA_RS27260
uniprot id: D2PN23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

479435:KFLA RS31280
gene id: 479435:KFLA_RS31280
uniprot id: D2PVR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS07160
gene id: 479435:KFLA_RS07160
uniprot id: D2PKP0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

479435:KFLA RS25345
gene id: 479435:KFLA_RS25345
uniprot id: D2Q3K5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

479435:KFLA RS06340
gene id: 479435:KFLA_RS06340
uniprot id: D2Q474
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

479435:KFLA RS24860
gene id: 479435:KFLA_RS24860
uniprot id: D2Q3A9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS30610
gene id: 479435:KFLA_RS30610
uniprot id: D2PUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

479435:KFLA RS07575
gene id: 479435:KFLA_RS07575
uniprot id: D2PLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS13800
gene id: 479435:KFLA_RS13800
uniprot id: D2PZ59
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

479435:KFLA RS26945
gene id: 479435:KFLA_RS26945
uniprot id: D2PM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

479435:KFLA RS27015
gene id: 479435:KFLA_RS27015
uniprot id: D2PM91
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

479435:KFLA RS08590
gene id: 479435:KFLA_RS08590
uniprot id: D2PNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

479435:KFLA RS02285
gene id: 479435:KFLA_RS02285
uniprot id: D2PUR2
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

479435:KFLA RS14995
gene id: 479435:KFLA_RS14995
uniprot id: D2Q1V3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS20700
gene id: 479435:KFLA_RS20700
uniprot id: D2PTS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS00020
gene id: 479435:KFLA_RS00020
uniprot id: D2PQE7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

479435:KFLA RS19110
gene id: 479435:KFLA_RS19110
uniprot id: D2PPX6
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

479435:KFLA RS03375
gene id: 479435:KFLA_RS03375
uniprot id: D2PXF0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS14245
gene id: 479435:KFLA_RS14245
uniprot id: D2Q0F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

479435:KFLA RS27065
gene id: 479435:KFLA_RS27065
uniprot id: D2PMA0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25965
gene id: 479435:KFLA_RS25965
uniprot id: D2Q4Z6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29915
gene id: 479435:KFLA_RS29915
uniprot id: D2PSX9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS16145
gene id: 479435:KFLA_RS16145
uniprot id: D2Q4K3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

479435:KFLA RS06430
gene id: 479435:KFLA_RS06430
uniprot id: D2Q492
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS02485
gene id: 479435:KFLA_RS02485
uniprot id: D2PVV4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

479435:KFLA RS15870
gene id: 479435:KFLA_RS15870
uniprot id: D2Q4F2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09005
gene id: 479435:KFLA_RS09005
uniprot id: D2PPF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

479435:KFLA RS35155
gene id: 479435:KFLA_RS35155
uniprot id: D2Q553
names: Similarity
messages: Belongs to the ParB family.

479435:KFLA RS30665
gene id: 479435:KFLA_RS30665
uniprot id: D2PUC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

479435:KFLA RS13770
gene id: 479435:KFLA_RS13770
uniprot id: D2PZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

479435:KFLA RS15975
gene id: 479435:KFLA_RS15975
uniprot id: D2Q4H2
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

479435:KFLA RS13570
gene id: 479435:KFLA_RS13570
uniprot id: D2PZ13
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

479435:KFLA RS13675
gene id: 479435:KFLA_RS13675
uniprot id: D2PZ34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

479435:KFLA RS29195
gene id: 479435:KFLA_RS29195
uniprot id: D2PRG9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

479435:KFLA RS14650
gene id: 479435:KFLA_RS14650
uniprot id: D2Q1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS29160
gene id: 479435:KFLA_RS29160
uniprot id: D2PRG2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

479435:KFLA RS05105
gene id: 479435:KFLA_RS05105
uniprot id: D2Q1F4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

479435:KFLA RS08575
gene id: 479435:KFLA_RS08575
uniprot id: D2PNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

479435:KFLA RS31210
gene id: 479435:KFLA_RS31210
uniprot id: D2PVP7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

479435:KFLA RS39215
gene id: 479435:KFLA_RS39215
uniprot id: D2Q552
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479435:KFLA RS02230
gene id: 479435:KFLA_RS02230
uniprot id: D2PUQ0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

479435:KFLA RS26665
gene id: 479435:KFLA_RS26665
uniprot id: D2PM26
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

479435:KFLA RS04370
gene id: 479435:KFLA_RS04370
uniprot id: D2PZZ4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479435:KFLA RS19860
gene id: 479435:KFLA_RS19860
uniprot id: D2PR99
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS04105
gene id: 479435:KFLA_RS04105
uniprot id: D2PYU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

479435:KFLA RS29880
gene id: 479435:KFLA_RS29880
uniprot id: D2PSX2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS18315
gene id: 479435:KFLA_RS18315
uniprot id: D2PNS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS02630
gene id: 479435:KFLA_RS02630
uniprot id: D2PVZ1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS05905
gene id: 479435:KFLA_RS05905
uniprot id: D2Q2W9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS30340
gene id: 479435:KFLA_RS30340
uniprot id: D2PU65
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS31755
gene id: 479435:KFLA_RS31755
uniprot id: D2PX11
names: Similarity
messages: Belongs to the histone deacetylase family.

479435:KFLA RS35075
gene id: 479435:KFLA_RS35075
uniprot id: D2Q535
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24435
gene id: 479435:KFLA_RS24435
uniprot id: D2Q1Z9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479435:KFLA RS00385
gene id: 479435:KFLA_RS00385
uniprot id: D2PQL8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS13785
gene id: 479435:KFLA_RS13785
uniprot id: D2PZ56
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS06660
gene id: 479435:KFLA_RS06660
uniprot id: D2PKD9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15695
gene id: 479435:KFLA_RS15695
uniprot id: D2Q3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

479435:KFLA RS14285
gene id: 479435:KFLA_RS14285
uniprot id: D2Q0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

479435:KFLA RS26080
gene id: 479435:KFLA_RS26080
uniprot id: D2PL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS38370
gene id: 479435:KFLA_RS38370
uniprot id: D2PR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS12065
gene id: 479435:KFLA_RS12065
uniprot id: D2PW60
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS20305
gene id: 479435:KFLA_RS20305
uniprot id: D2PSJ4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30400
gene id: 479435:KFLA_RS30400
uniprot id: D2PU77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

479435:KFLA RS06605
gene id: 479435:KFLA_RS06605
uniprot id: D2PKC8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

479435:KFLA RS25870
gene id: 479435:KFLA_RS25870
uniprot id: D2Q4X8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

479435:KFLA RS30945
gene id: 479435:KFLA_RS30945
uniprot id: D2PVJ2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS00540
gene id: 479435:KFLA_RS00540
uniprot id: D2PRQ6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS11045
gene id: 479435:KFLA_RS11045
uniprot id: D2PTK2
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

479435:KFLA RS25945
gene id: 479435:KFLA_RS25945
uniprot id: D2Q4Z2
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS11910
gene id: 479435:KFLA_RS11910
uniprot id: D2PV15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS32490
gene id: 479435:KFLA_RS32490
uniprot id: D2PYH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479435:KFLA RS38635
gene id: 479435:KFLA_RS38635
uniprot id: D2PVZ8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

479435:KFLA RS17270
gene id: 479435:KFLA_RS17270
uniprot id: D2PLV3
names: Similarity
messages: Belongs to the thymidine kinase family.

479435:KFLA RS15705
gene id: 479435:KFLA_RS15705
uniprot id: D2Q4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

479435:KFLA RS31400
gene id: 479435:KFLA_RS31400
uniprot id: D2PWU4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30965
gene id: 479435:KFLA_RS30965
uniprot id: D2PVJ6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

479435:KFLA RS02110
gene id: 479435:KFLA_RS02110
uniprot id: D2PUM8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

479435:KFLA RS04970
gene id: 479435:KFLA_RS04970
uniprot id: D2Q1C7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS30970
gene id: 479435:KFLA_RS30970
uniprot id: D2PVJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS06530
gene id: 479435:KFLA_RS06530
uniprot id: D2Q4B1
names: Similarity
messages: Belongs to the peptidase S11 family.

479435:KFLA RS16925
gene id: 479435:KFLA_RS16925
uniprot id: D2PKZ9
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

479435:KFLA RS08355
gene id: 479435:KFLA_RS08355
uniprot id: D2PND5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14930
gene id: 479435:KFLA_RS14930
uniprot id: D2Q1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

479435:KFLA RS13015
gene id: 479435:KFLA_RS13015
uniprot id: D2PXQ9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18030
gene id: 479435:KFLA_RS18030
uniprot id: D2PMY5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

479435:KFLA RS07005
gene id: 479435:KFLA_RS07005
uniprot id: D2PKK7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS00250
gene id: 479435:KFLA_RS00250
uniprot id: D2PQJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

479435:KFLA RS25090
gene id: 479435:KFLA_RS25090
uniprot id: D2Q3F5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS08495
gene id: 479435:KFLA_RS08495
uniprot id: D2PNG4
names: Similarity
messages: Belongs to the serpin family.

479435:KFLA RS35965
gene id: 479435:KFLA_RS35965
uniprot id: D2PM74
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

479435:KFLA RS08775
gene id: 479435:KFLA_RS08775
uniprot id: D2PNM1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

479435:KFLA RS18550
gene id: 479435:KFLA_RS18550
uniprot id: D2PNX2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479435:KFLA RS05875
gene id: 479435:KFLA_RS05875
uniprot id: D2Q2W3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14065
gene id: 479435:KFLA_RS14065
uniprot id: D2Q0B4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS16215
gene id: 479435:KFLA_RS16215
uniprot id: D2Q4L7
names: Similarity
messages: Belongs to the GPI family.

479435:KFLA RS24235
gene id: 479435:KFLA_RS24235
uniprot id: D2Q0V5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS08465
gene id: 479435:KFLA_RS08465
uniprot id: D2PNF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS27985
gene id: 479435:KFLA_RS27985
uniprot id: D2PP52
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

479435:KFLA RS09525
gene id: 479435:KFLA_RS09525
uniprot id: D2PPQ9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14415
gene id: 479435:KFLA_RS14415
uniprot id: D2Q0I4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

479435:KFLA RS08525
gene id: 479435:KFLA_RS08525
uniprot id: D2PNH0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

479435:KFLA RS04730
gene id: 479435:KFLA_RS04730
uniprot id: D2Q068
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

479435:KFLA RS26635
gene id: 479435:KFLA_RS26635
uniprot id: D2PM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS05975
gene id: 479435:KFLA_RS05975
uniprot id: D2Q400
names: Similarity
messages: Belongs to the peptidase M13 family.

479435:KFLA RS06825
gene id: 479435:KFLA_RS06825
uniprot id: D2PKH1
names: Similarity
messages: Belongs to the peptidase S66 family.

479435:KFLA RS23985
gene id: 479435:KFLA_RS23985
uniprot id: D2Q0Q6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

479435:KFLA RS10445
gene id: 479435:KFLA_RS10445
uniprot id: D2PS73
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

479435:KFLA RS24455
gene id: 479435:KFLA_RS24455
uniprot id: D2Q203
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS20620
gene id: 479435:KFLA_RS20620
uniprot id: D2PSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

479435:KFLA RS21550
gene id: 479435:KFLA_RS21550
uniprot id: D2PV95
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

479435:KFLA RS16870
gene id: 479435:KFLA_RS16870
uniprot id: D2PKY9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479435:KFLA RS12990
gene id: 479435:KFLA_RS12990
uniprot id: D2PXQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS23915
gene id: 479435:KFLA_RS23915
uniprot id: D2Q0P3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

479435:KFLA RS33190
gene id: 479435:KFLA_RS33190
uniprot id: D2Q0X1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

479435:KFLA RS08445
gene id: 479435:KFLA_RS08445
uniprot id: D2PNF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

479435:KFLA RS18035
gene id: 479435:KFLA_RS18035
uniprot id: D2PMY6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS26835
gene id: 479435:KFLA_RS26835
uniprot id: D2PM59
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS28525
gene id: 479435:KFLA_RS28525
uniprot id: D2PQ52
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30035
gene id: 479435:KFLA_RS30035
uniprot id: D2PT03
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

479435:KFLA RS27235
gene id: 479435:KFLA_RS27235
uniprot id: D2PN18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

479435:KFLA RS31670
gene id: 479435:KFLA_RS31670
uniprot id: D2PWZ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

479435:KFLA RS28260
gene id: 479435:KFLA_RS28260
uniprot id: D2PPA6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

479435:KFLA RS33060
gene id: 479435:KFLA_RS33060
uniprot id: D2PZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS16270
gene id: 479435:KFLA_RS16270
uniprot id: D2Q4M8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

479435:KFLA RS27825
gene id: 479435:KFLA_RS27825
uniprot id: D2PND2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

479435:KFLA RS01215
gene id: 479435:KFLA_RS01215
uniprot id: D2PT56
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18440
gene id: 479435:KFLA_RS18440
uniprot id: D2PNV0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

479435:KFLA RS10910
gene id: 479435:KFLA_RS10910
uniprot id: D2PTH5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS08995
gene id: 479435:KFLA_RS08995
uniprot id: D2PPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS31855
gene id: 479435:KFLA_RS31855
uniprot id: D2PX30
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

479435:KFLA RS08635
gene id: 479435:KFLA_RS08635
uniprot id: D2PNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS10565
gene id: 479435:KFLA_RS10565
uniprot id: D2PS97
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23270
gene id: 479435:KFLA_RS23270
uniprot id: D2PZA5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

479435:KFLA RS14965
gene id: 479435:KFLA_RS14965
uniprot id: D2Q1U7
names: Similarity
messages: Belongs to the thioredoxin family.

479435:KFLA RS31415
gene id: 479435:KFLA_RS31415
uniprot id: D2PWU7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS08160
gene id: 479435:KFLA_RS08160
uniprot id: D2PMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

479435:KFLA RS21380
gene id: 479435:KFLA_RS21380
uniprot id: D2PV61
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS20010
gene id: 479435:KFLA_RS20010
uniprot id: D2PRC8
names: Similarity
messages: Belongs to the Gfa family.

479435:KFLA RS27080
gene id: 479435:KFLA_RS27080
uniprot id: D2PMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS37120
gene id: 479435:KFLA_RS37120
uniprot id: D2PVF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

479435:KFLA RS23990
gene id: 479435:KFLA_RS23990
uniprot id: D2Q0Q7
names: Similarity
messages: Belongs to the cytochrome P450 family.

479435:KFLA RS10600
gene id: 479435:KFLA_RS10600
uniprot id: D2PSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

479435:KFLA RS24295
gene id: 479435:KFLA_RS24295
uniprot id: D2Q1X1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

479435:KFLA RS07195
gene id: 479435:KFLA_RS07195
uniprot id: D2PLD0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS22395
gene id: 479435:KFLA_RS22395
uniprot id: D2PWS2
names: Similarity
messages: Belongs to the DapA family.

479435:KFLA RS24980
gene id: 479435:KFLA_RS24980
uniprot id: D2Q3D3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

479435:KFLA RS15760
gene id: 479435:KFLA_RS15760
uniprot id: D2Q4D0
names: Similarity
messages: Belongs to the group II decarboxylase family.

479435:KFLA RS16330
gene id: 479435:KFLA_RS16330
uniprot id: D2Q4P0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30385
gene id: 479435:KFLA_RS30385
uniprot id: D2PU74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

479435:KFLA RS15860
gene id: 479435:KFLA_RS15860
uniprot id: D2Q4F0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS31040
gene id: 479435:KFLA_RS31040
uniprot id: D2PVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

479435:KFLA RS27975
gene id: 479435:KFLA_RS27975
uniprot id: D2PP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

479435:KFLA RS27710
gene id: 479435:KFLA_RS27710
uniprot id: D2PNA9
names: Similarity
messages: Belongs to the FBPase class 2 family.

479435:KFLA RS21985
gene id: 479435:KFLA_RS21985
uniprot id: D2PWJ3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS17205
gene id: 479435:KFLA_RS17205
uniprot id: D2PLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

479435:KFLA RS21250
gene id: 479435:KFLA_RS21250
uniprot id: D2PU33
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

479435:KFLA RS30435
gene id: 479435:KFLA_RS30435
uniprot id: D2PU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

479435:KFLA RS34120
gene id: 479435:KFLA_RS34120
uniprot id: D2Q2F9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

479435:KFLA RS08085
gene id: 479435:KFLA_RS08085
uniprot id: D2PMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS32195
gene id: 479435:KFLA_RS32195
uniprot id: D2PYB0
names: Similarity
messages: Belongs to the UPF0045 family.

479435:KFLA RS19740
gene id: 479435:KFLA_RS19740
uniprot id: D2PR76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

479435:KFLA RS31535
gene id: 479435:KFLA_RS31535
uniprot id: D2PWX0
names: Similarity
messages: Belongs to the cytochrome P450 family.

479435:KFLA RS33955
gene id: 479435:KFLA_RS33955
uniprot id: D2Q2C6
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

479435:KFLA RS21425
gene id: 479435:KFLA_RS21425
uniprot id: D2PV68
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

479435:KFLA RS08405
gene id: 479435:KFLA_RS08405
uniprot id: D2PNE6
names: Similarity
messages: Belongs to the GSP E family.

479435:KFLA RS20145
gene id: 479435:KFLA_RS20145
uniprot id: D2PSG5
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS02920
gene id: 479435:KFLA_RS02920
uniprot id: D2PX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

479435:KFLA RS21655
gene id: 479435:KFLA_RS21655
uniprot id: D2PVB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS05285
gene id: 479435:KFLA_RS05285
uniprot id: D2Q1J0
names: Similarity
messages: Belongs to the peptidase C56 family.

479435:KFLA RS23305
gene id: 479435:KFLA_RS23305
uniprot id: D2PZB2
names: Similarity
messages: Belongs to the TPP enzyme family.

479435:KFLA RS23565
gene id: 479435:KFLA_RS23565
uniprot id: D2PZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

479435:KFLA RS02325
gene id: 479435:KFLA_RS02325
uniprot id: D2PVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS12145
gene id: 479435:KFLA_RS12145
uniprot id: D2PW76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS26285
gene id: 479435:KFLA_RS26285
uniprot id: D2PL63
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS07880
gene id: 479435:KFLA_RS07880
uniprot id: D2PMF0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

479435:KFLA RS24590
gene id: 479435:KFLA_RS24590
uniprot id: D2Q231
names: Similarity
messages: Belongs to the citrate synthase family.

479435:KFLA RS12705
gene id: 479435:KFLA_RS12705
uniprot id: D2PXJ6
names: Similarity
messages: Belongs to the CdaR family.

479435:KFLA RS25120
gene id: 479435:KFLA_RS25120
uniprot id: D2Q3G1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS27810
gene id: 479435:KFLA_RS27810
uniprot id: D2PNC9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS27395
gene id: 479435:KFLA_RS27395
uniprot id: D2PN49
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

479435:KFLA RS01000
gene id: 479435:KFLA_RS01000
uniprot id: D2PS00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

479435:KFLA RS16325
gene id: 479435:KFLA_RS16325
uniprot id: D2Q4N9
names: Similarity
messages: Belongs to the GSP E family.

479435:KFLA RS06800
gene id: 479435:KFLA_RS06800
uniprot id: D2PKG7
names: Similarity
messages: Belongs to the peptidase M1 family.

479435:KFLA RS08960
gene id: 479435:KFLA_RS08960
uniprot id: D2PPE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS09820
gene id: 479435:KFLA_RS09820
uniprot id: D2PQU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS14325
gene id: 479435:KFLA_RS14325
uniprot id: D2Q0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

479435:KFLA RS17170
gene id: 479435:KFLA_RS17170
uniprot id: D2PLT3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15000
gene id: 479435:KFLA_RS15000
uniprot id: D2Q1V4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS12685
gene id: 479435:KFLA_RS12685
uniprot id: D2PXJ2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

479435:KFLA RS29345
gene id: 479435:KFLA_RS29345
uniprot id: D2PRJ8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS32055
gene id: 479435:KFLA_RS32055
uniprot id: D2PY82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS15205
gene id: 479435:KFLA_RS15205
uniprot id: D2Q309
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

479435:KFLA RS25500
gene id: 479435:KFLA_RS25500
uniprot id: D2Q4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS01850
gene id: 479435:KFLA_RS01850
uniprot id: D2PUH8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS33385
gene id: 479435:KFLA_RS33385
uniprot id: D2Q109
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

479435:KFLA RS18080
gene id: 479435:KFLA_RS18080
uniprot id: D2PMZ5
names: Similarity
messages: Belongs to the peptidase M24B family.

479435:KFLA RS13030
gene id: 479435:KFLA_RS13030
uniprot id: D2PXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

479435:KFLA RS32410
gene id: 479435:KFLA_RS32410
uniprot id: D2PYF4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS10525
gene id: 479435:KFLA_RS10525
uniprot id: D2PS89
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479435:KFLA RS04965
gene id: 479435:KFLA_RS04965
uniprot id: D2Q1C6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

479435:KFLA RS08885
gene id: 479435:KFLA_RS08885
uniprot id: D2PNP2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

479435:KFLA RS03910
gene id: 479435:KFLA_RS03910
uniprot id: D2PYQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

479435:KFLA RS13615
gene id: 479435:KFLA_RS13615
uniprot id: D2PZ22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS15240
gene id: 479435:KFLA_RS15240
uniprot id: D2Q316
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

479435:KFLA RS16385
gene id: 479435:KFLA_RS16385
uniprot id: D2PKP8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

479435:KFLA RS21480
gene id: 479435:KFLA_RS21480
uniprot id: D2PV80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

479435:KFLA RS26745
gene id: 479435:KFLA_RS26745
uniprot id: D2PM42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS16335
gene id: 479435:KFLA_RS16335
uniprot id: D2Q4P1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS16240
gene id: 479435:KFLA_RS16240
uniprot id: D2Q4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

479435:KFLA RS30395
gene id: 479435:KFLA_RS30395
uniprot id: D2PU76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS23060
gene id: 479435:KFLA_RS23060
uniprot id: D2PY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS29730
gene id: 479435:KFLA_RS29730
uniprot id: D2PSU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

479435:KFLA RS07425
gene id: 479435:KFLA_RS07425
uniprot id: D2PLH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS01030
gene id: 479435:KFLA_RS01030
uniprot id: D2PS06
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS19595
gene id: 479435:KFLA_RS19595
uniprot id: D2PR47
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

479435:KFLA RS22940
gene id: 479435:KFLA_RS22940
uniprot id: D2PY45
names: Similarity
messages: Belongs to the hyi family.

479435:KFLA RS12790
gene id: 479435:KFLA_RS12790
uniprot id: D2PXL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

479435:KFLA RS27300
gene id: 479435:KFLA_RS27300
uniprot id: D2PN31
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M7 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS24335
gene id: 479435:KFLA_RS24335
uniprot id: D2Q1X9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

479435:KFLA RS27665
gene id: 479435:KFLA_RS27665
uniprot id: D2PNA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

479435:KFLA RS09690
gene id: 479435:KFLA_RS09690
uniprot id: D2PQS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS10100
gene id: 479435:KFLA_RS10100
uniprot id: D2PR02
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS11105
gene id: 479435:KFLA_RS11105
uniprot id: D2PTL4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

479435:KFLA RS26565
gene id: 479435:KFLA_RS26565
uniprot id: D2PLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

479435:KFLA RS13575
gene id: 479435:KFLA_RS13575
uniprot id: D2PZ14
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS15980
gene id: 479435:KFLA_RS15980
uniprot id: D2Q4H3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

479435:KFLA RS22355
gene id: 479435:KFLA_RS22355
uniprot id: D2PWR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

479435:KFLA RS09065
gene id: 479435:KFLA_RS09065
uniprot id: D2PPG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

479435:KFLA RS12440
gene id: 479435:KFLA_RS12440
uniprot id: D2PWD6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

479435:KFLA RS31610
gene id: 479435:KFLA_RS31610
uniprot id: D2PWY4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

479435:KFLA RS14845
gene id: 479435:KFLA_RS14845
uniprot id: D2Q1S3
names: Similarity
messages: Belongs to the FPG family.

479435:KFLA RS02480
gene id: 479435:KFLA_RS02480
uniprot id: D2PVW1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

479435:KFLA RS35365
gene id: 479435:KFLA_RS35365
uniprot id: D2Q1E5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS16185
gene id: 479435:KFLA_RS16185
uniprot id: D2Q4L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

479435:KFLA RS30405
gene id: 479435:KFLA_RS30405
uniprot id: D2PU78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

479435:KFLA RS11520
gene id: 479435:KFLA_RS11520
uniprot id: D2PUT9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21970
gene id: 479435:KFLA_RS21970
uniprot id: D2PWJ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS30355
gene id: 479435:KFLA_RS30355
uniprot id: D2PU68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

479435:KFLA RS19990
gene id: 479435:KFLA_RS19990
uniprot id: D2PRC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS18410
gene id: 479435:KFLA_RS18410
uniprot id: D2PNU4
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

479435:KFLA RS07525
gene id: 479435:KFLA_RS07525
uniprot id: D2PLJ5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23295
gene id: 479435:KFLA_RS23295
uniprot id: D2PZB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

479435:KFLA RS07350
gene id: 479435:KFLA_RS07350
uniprot id: D2PLG0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS33905
gene id: 479435:KFLA_RS33905
uniprot id: D2Q2B7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS06525
gene id: 479435:KFLA_RS06525
uniprot id: D2Q4B0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS35010
gene id: 479435:KFLA_RS35010
uniprot id: D2Q522
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS23435
gene id: 479435:KFLA_RS23435
uniprot id: D2PZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS29905
gene id: 479435:KFLA_RS29905
uniprot id: D2PSX7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

479435:KFLA RS09025
gene id: 479435:KFLA_RS09025
uniprot id: D2PPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS14765
gene id: 479435:KFLA_RS14765
uniprot id: D2Q1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

479435:KFLA RS12740
gene id: 479435:KFLA_RS12740
uniprot id: D2PXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

479435:KFLA RS13695
gene id: 479435:KFLA_RS13695
uniprot id: D2PZ38
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

479435:KFLA RS02845
gene id: 479435:KFLA_RS02845
uniprot id: D2PW35
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

479435:KFLA RS18355
gene id: 479435:KFLA_RS18355
uniprot id: D2PNT3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

479435:KFLA RS09925
gene id: 479435:KFLA_RS09925
uniprot id: D2PQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS08400
gene id: 479435:KFLA_RS08400
uniprot id: D2PNE5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS21795
gene id: 479435:KFLA_RS21795
uniprot id: D2PVE3
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

479435:KFLA RS08975
gene id: 479435:KFLA_RS08975
uniprot id: D2PPF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

479435:KFLA RS23525
gene id: 479435:KFLA_RS23525
uniprot id: D2PZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

479435:KFLA RS25025
gene id: 479435:KFLA_RS25025
uniprot id: D2Q3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

479435:KFLA RS09940
gene id: 479435:KFLA_RS09940
uniprot id: D2PQX0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

479435:KFLA RS07720
gene id: 479435:KFLA_RS07720
uniprot id: D2PLN4
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS05495
gene id: 479435:KFLA_RS05495
uniprot id: D2Q2N8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS07400
gene id: 479435:KFLA_RS07400
uniprot id: D2PLH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS25900
gene id: 479435:KFLA_RS25900
uniprot id: D2Q4Y3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15095
gene id: 479435:KFLA_RS15095
uniprot id: D2Q2Y7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

479435:KFLA RS29780
gene id: 479435:KFLA_RS29780
uniprot id: D2PSV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

479435:KFLA RS14610
gene id: 479435:KFLA_RS14610
uniprot id: D2Q1M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

479435:KFLA RS17445
gene id: 479435:KFLA_RS17445
uniprot id: D2PLY8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14460
gene id: 479435:KFLA_RS14460
uniprot id: D2Q0J3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

479435:KFLA RS24970
gene id: 479435:KFLA_RS24970
uniprot id: D2Q3D1
names: Subunit
messages: Monomer.

479435:KFLA RS32730
gene id: 479435:KFLA_RS32730
uniprot id: D2PZL8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS07150
gene id: 479435:KFLA_RS07150
uniprot id: D2PKN8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

479435:KFLA RS30345
gene id: 479435:KFLA_RS30345
uniprot id: D2PU66
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

479435:KFLA RS10515
gene id: 479435:KFLA_RS10515
uniprot id: D2PS87
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

479435:KFLA RS07655
gene id: 479435:KFLA_RS07655
uniprot id: D2PLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

479435:KFLA RS11705
gene id: 479435:KFLA_RS11705
uniprot id: D2PUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

479435:KFLA RS06110
gene id: 479435:KFLA_RS06110
uniprot id: D2Q427
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS13425
gene id: 479435:KFLA_RS13425
uniprot id: D2PYY4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

479435:KFLA RS29370
gene id: 479435:KFLA_RS29370
uniprot id: D2PRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

479435:KFLA RS01150
gene id: 479435:KFLA_RS01150
uniprot id: D2PT42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS26855
gene id: 479435:KFLA_RS26855
uniprot id: D2PM63
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

479435:KFLA RS22015
gene id: 479435:KFLA_RS22015
uniprot id: D2PWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

479435:KFLA RS04270
gene id: 479435:KFLA_RS04270
uniprot id: D2PZX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

479435:KFLA RS18490
gene id: 479435:KFLA_RS18490
uniprot id: D2PNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

479435:KFLA RS02675
gene id: 479435:KFLA_RS02675
uniprot id: D2PW00
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30570
gene id: 479435:KFLA_RS30570
uniprot id: D2PUB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

479435:KFLA RS07795
gene id: 479435:KFLA_RS07795
uniprot id: D2PMD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS33720
gene id: 479435:KFLA_RS33720
uniprot id: D2Q175
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS25015
gene id: 479435:KFLA_RS25015
uniprot id: D2Q3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

479435:KFLA RS17060
gene id: 479435:KFLA_RS17060
uniprot id: D2PLR1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS16690
gene id: 479435:KFLA_RS16690
uniprot id: D2PKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS13065
gene id: 479435:KFLA_RS13065
uniprot id: D2PXR8
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

479435:KFLA RS06325
gene id: 479435:KFLA_RS06325
uniprot id: D2Q471
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18185
gene id: 479435:KFLA_RS18185
uniprot id: D2PN15
names: Subcellular Location Annotation
messages: Cytoplasm

479435:KFLA RS08970
gene id: 479435:KFLA_RS08970
uniprot id: D2PPE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

479435:KFLA RS07455
gene id: 479435:KFLA_RS07455
uniprot id: D2PLI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS16510
gene id: 479435:KFLA_RS16510
uniprot id: D2PKS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS08295
gene id: 479435:KFLA_RS08295
uniprot id: D2PMN1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS26915
gene id: 479435:KFLA_RS26915
uniprot id: D2PM71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS27860
gene id: 479435:KFLA_RS27860
uniprot id: D2PP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS21310
gene id: 479435:KFLA_RS21310
uniprot id: D2PV47
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS05505
gene id: 479435:KFLA_RS05505
uniprot id: D2Q2P0
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

479435:KFLA RS29620
gene id: 479435:KFLA_RS29620
uniprot id: D2PSR9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

479435:KFLA RS18735
gene id: 479435:KFLA_RS18735
uniprot id: D2PP08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS02445
gene id: 479435:KFLA_RS02445
uniprot id: D2PVV4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

479435:KFLA RS14935
gene id: 479435:KFLA_RS14935
uniprot id: D2Q1U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

479435:KFLA RS22695
gene id: 479435:KFLA_RS22695
uniprot id: D2PXZ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

479435:KFLA RS19615
gene id: 479435:KFLA_RS19615
uniprot id: D2PR51
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS16820
gene id: 479435:KFLA_RS16820
uniprot id: D2PKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

479435:KFLA RS13325
gene id: 479435:KFLA_RS13325
uniprot id: D2PYW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

479435:KFLA RS04975
gene id: 479435:KFLA_RS04975
uniprot id: D2Q1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS05475
gene id: 479435:KFLA_RS05475
uniprot id: D2Q2N4
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS13410
gene id: 479435:KFLA_RS13410
uniprot id: D2PYY1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24040
gene id: 479435:KFLA_RS24040
uniprot id: D2Q0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

479435:KFLA RS15210
gene id: 479435:KFLA_RS15210
uniprot id: D2Q310
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS27620
gene id: 479435:KFLA_RS27620
uniprot id: D2PN92
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

479435:KFLA RS14335
gene id: 479435:KFLA_RS14335
uniprot id: D2Q0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

479435:KFLA RS11320
gene id: 479435:KFLA_RS11320
uniprot id: D2PTQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

479435:KFLA RS33680
gene id: 479435:KFLA_RS33680
uniprot id: D2Q167
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

479435:KFLA RS14340
gene id: 479435:KFLA_RS14340
uniprot id: D2Q0G8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

479435:KFLA RS15780
gene id: 479435:KFLA_RS15780
uniprot id: D2Q4D4
names: Similarity
messages: Belongs to the IucA/IucC family.

479435:KFLA RS27445
gene id: 479435:KFLA_RS27445
uniprot id: D2PN58
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS11335
gene id: 479435:KFLA_RS11335
uniprot id: D2PTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

479435:KFLA RS26410
gene id: 479435:KFLA_RS26410
uniprot id: D2PL86
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06020
gene id: 479435:KFLA_RS06020
uniprot id: D2Q409
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

479435:KFLA RS01575
gene id: 479435:KFLA_RS01575
uniprot id: D2PTC5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

479435:KFLA RS33355
gene id: 479435:KFLA_RS33355
uniprot id: D2Q104
names: Similarity
messages: Belongs to the ComB family.

479435:KFLA RS25380
gene id: 479435:KFLA_RS25380
uniprot id: D2Q3L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

479435:KFLA RS18570
gene id: 479435:KFLA_RS18570
uniprot id: D2PNX6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30350
gene id: 479435:KFLA_RS30350
uniprot id: D2PU67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

479435:KFLA RS28940
gene id: 479435:KFLA_RS28940
uniprot id: D2PQD4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

479435:KFLA RS01265
gene id: 479435:KFLA_RS01265
uniprot id: D2PT66
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS32480
gene id: 479435:KFLA_RS32480
uniprot id: D2PYG8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

479435:KFLA RS11565
gene id: 479435:KFLA_RS11565
uniprot id: D2PUU8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS04670
gene id: 479435:KFLA_RS04670
uniprot id: D2Q056
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

479435:KFLA RS32505
gene id: 479435:KFLA_RS32505
uniprot id: D2PYH3
names: Similarity
messages: Belongs to the peptidase S1 family.

479435:KFLA RS25905
gene id: 479435:KFLA_RS25905
uniprot id: D2Q4Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479435:KFLA RS18335
gene id: 479435:KFLA_RS18335
uniprot id: D2PNS9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS05220
gene id: 479435:KFLA_RS05220
uniprot id: D2Q1H7
names: Similarity
messages: Belongs to the CsoR family.

479435:KFLA RS14350
gene id: 479435:KFLA_RS14350
uniprot id: D2Q0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

479435:KFLA RS16165
gene id: 479435:KFLA_RS16165
uniprot id: D2Q4K7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

479435:KFLA RS06705
gene id: 479435:KFLA_RS06705
uniprot id: D2PKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS33250
gene id: 479435:KFLA_RS33250
uniprot id: D2Q0Y3
names: Similarity
messages: Belongs to the GARS family.

479435:KFLA RS07960
gene id: 479435:KFLA_RS07960
uniprot id: D2PMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS18170
gene id: 479435:KFLA_RS18170
uniprot id: D2PN12
names: Similarity
messages: Belongs to the fructosamine kinase family.

479435:KFLA RS02100
gene id: 479435:KFLA_RS02100
uniprot id: D2PUM6
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS15465
gene id: 479435:KFLA_RS15465
uniprot id: D2Q361
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

479435:KFLA RS30625
gene id: 479435:KFLA_RS30625
uniprot id: D2PUC1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

479435:KFLA RS20985
gene id: 479435:KFLA_RS20985
uniprot id: D2PTY3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS02740
gene id: 479435:KFLA_RS02740
uniprot id: D2PW13
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

479435:KFLA RS34445
gene id: 479435:KFLA_RS34445
uniprot id: D2Q3P9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

479435:KFLA RS18625
gene id: 479435:KFLA_RS18625
uniprot id: D2PNY7
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS09730
gene id: 479435:KFLA_RS09730
uniprot id: D2PQS9
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS14530
gene id: 479435:KFLA_RS14530
uniprot id: D2Q1K9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

479435:KFLA RS02850
gene id: 479435:KFLA_RS02850
uniprot id: D2PW36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

479435:KFLA RS31275
gene id: 479435:KFLA_RS31275
uniprot id: D2PVR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS23740
gene id: 479435:KFLA_RS23740
uniprot id: D2Q0K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

479435:KFLA RS27125
gene id: 479435:KFLA_RS27125
uniprot id: D2PMB2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09120
gene id: 479435:KFLA_RS09120
uniprot id: D2PPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

479435:KFLA RS20660
gene id: 479435:KFLA_RS20660
uniprot id: D2PTS2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS06875
gene id: 479435:KFLA_RS06875
uniprot id: D2PKI1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

479435:KFLA RS13205
gene id: 479435:KFLA_RS13205
uniprot id: D2PXU5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS19190
gene id: 479435:KFLA_RS19190
uniprot id: D2PPZ2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

479435:KFLA RS27795
gene id: 479435:KFLA_RS27795
uniprot id: D2PNC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS11795
gene id: 479435:KFLA_RS11795
uniprot id: D2PUZ2
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS19485
gene id: 479435:KFLA_RS19485
uniprot id: D2PR26
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS28440
gene id: 479435:KFLA_RS28440
uniprot id: D2PQ35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

479435:KFLA RS13085
gene id: 479435:KFLA_RS13085
uniprot id: D2PXS2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

479435:KFLA RS23530
gene id: 479435:KFLA_RS23530
uniprot id: D2PZF7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18655
gene id: 479435:KFLA_RS18655
uniprot id: D2PNZ3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

479435:KFLA RS15555
gene id: 479435:KFLA_RS15555
uniprot id: D2Q378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS02520
gene id: 479435:KFLA_RS02520
uniprot id: D2PVW9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

479435:KFLA RS14280
gene id: 479435:KFLA_RS14280
uniprot id: D2Q0F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

479435:KFLA RS14315
gene id: 479435:KFLA_RS14315
uniprot id: D2Q0G3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

479435:KFLA RS32025
gene id: 479435:KFLA_RS32025
uniprot id: D2PY76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

479435:KFLA RS03670
gene id: 479435:KFLA_RS03670
uniprot id: D2PYL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

479435:KFLA RS32550
gene id: 479435:KFLA_RS32550
uniprot id: D2PYI1
names: Similarity
messages: Belongs to the proline racemase family.

479435:KFLA RS23575
gene id: 479435:KFLA_RS23575
uniprot id: D2PZG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

479435:KFLA RS01800
gene id: 479435:KFLA_RS01800
uniprot id: D2PUG8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS33480
gene id: 479435:KFLA_RS33480
uniprot id: D2Q128
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

479435:KFLA RS06210
gene id: 479435:KFLA_RS06210
uniprot id: D2Q447
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS25110
gene id: 479435:KFLA_RS25110
uniprot id: D2Q3F9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

479435:KFLA RS17840
gene id: 479435:KFLA_RS17840
uniprot id: D2PMU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS30575
gene id: 479435:KFLA_RS30575
uniprot id: D2PUB1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06555
gene id: 479435:KFLA_RS06555
uniprot id: D2Q4B6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS31235
gene id: 479435:KFLA_RS31235
uniprot id: D2PVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS31145
gene id: 479435:KFLA_RS31145
uniprot id: D2PVN4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

479435:KFLA RS01375
gene id: 479435:KFLA_RS01375
uniprot id: D2PT87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS30365
gene id: 479435:KFLA_RS30365
uniprot id: D2PU70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

479435:KFLA RS30370
gene id: 479435:KFLA_RS30370
uniprot id: D2PU71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

479435:KFLA RS11090
gene id: 479435:KFLA_RS11090
uniprot id: D2PTL1
names: Similarity
messages: Belongs to the peptidase M1 family.

479435:KFLA RS15880
gene id: 479435:KFLA_RS15880
uniprot id: D2Q4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

479435:KFLA RS08630
gene id: 479435:KFLA_RS08630
uniprot id: D2PNJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase.

479435:KFLA RS34500
gene id: 479435:KFLA_RS34500
uniprot id: D2Q3Q9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS18270
gene id: 479435:KFLA_RS18270
uniprot id: D2PNR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

479435:KFLA RS04265
gene id: 479435:KFLA_RS04265
uniprot id: D2PZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

479435:KFLA RS33615
gene id: 479435:KFLA_RS33615
uniprot id: D2Q154
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

479435:KFLA RS17295
gene id: 479435:KFLA_RS17295
uniprot id: D2PLV8
names: Similarity
messages: Belongs to the DapA family.

479435:KFLA RS04510
gene id: 479435:KFLA_RS04510
uniprot id: D2Q023
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

479435:KFLA RS29955
gene id: 479435:KFLA_RS29955
uniprot id: D2PSY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

479435:KFLA RS24855
gene id: 479435:KFLA_RS24855
uniprot id: D2Q3A8
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

479435:KFLA RS23720
gene id: 479435:KFLA_RS23720
uniprot id: D2Q0K4
names: Similarity
messages: Belongs to the asparaginase 1 family.

479435:KFLA RS26435
gene id: 479435:KFLA_RS26435
uniprot id: D2PL93
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

479435:KFLA RS23440
gene id: 479435:KFLA_RS23440
uniprot id: D2PZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS17975
gene id: 479435:KFLA_RS17975
uniprot id: D2PMX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

479435:KFLA RS30715
gene id: 479435:KFLA_RS30715
uniprot id: D2PUD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

479435:KFLA RS06965
gene id: 479435:KFLA_RS06965
uniprot id: D2PKJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

479435:KFLA RS00145
gene id: 479435:KFLA_RS00145
uniprot id: D2PQH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS20545
gene id: 479435:KFLA_RS20545
uniprot id: D2PSP3
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

479435:KFLA RS09335
gene id: 479435:KFLA_RS09335
uniprot id: D2PPM0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

479435:KFLA RS20725
gene id: 479435:KFLA_RS20725
uniprot id: D2PTT4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24330
gene id: 479435:KFLA_RS24330
uniprot id: D2Q1X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS25105
gene id: 479435:KFLA_RS25105
uniprot id: D2Q3F8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

479435:KFLA RS24200
gene id: 479435:KFLA_RS24200
uniprot id: D2Q0U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS05045
gene id: 479435:KFLA_RS05045
uniprot id: D2Q1E2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06350
gene id: 479435:KFLA_RS06350
uniprot id: D2Q476
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

479435:KFLA RS13390
gene id: 479435:KFLA_RS13390
uniprot id: D2PYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

479435:KFLA RS31290
gene id: 479435:KFLA_RS31290
uniprot id: D2PVR3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

479435:KFLA RS31485
gene id: 479435:KFLA_RS31485
uniprot id: D2PWW0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23760
gene id: 479435:KFLA_RS23760
uniprot id: D2Q0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

479435:KFLA RS30105
gene id: 479435:KFLA_RS30105
uniprot id: D2PT17
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

479435:KFLA RS06920
gene id: 479435:KFLA_RS06920
uniprot id: D2PKJ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

479435:KFLA RS04675
gene id: 479435:KFLA_RS04675
uniprot id: D2Q057
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30605
gene id: 479435:KFLA_RS30605
uniprot id: D2PUB7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

479435:KFLA RS33590
gene id: 479435:KFLA_RS33590
uniprot id: D2Q150
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

479435:KFLA RS19490
gene id: 479435:KFLA_RS19490
uniprot id: D2PR27
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS15090
gene id: 479435:KFLA_RS15090
uniprot id: D2Q2Y6
names: Similarity
messages: Belongs to the peptidase S13 family.

479435:KFLA RS04020
gene id: 479435:KFLA_RS04020
uniprot id: D2PYS8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29020
gene id: 479435:KFLA_RS29020
uniprot id: D2PRD4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

479435:KFLA RS24775
gene id: 479435:KFLA_RS24775
uniprot id: D2Q269
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS17725
gene id: 479435:KFLA_RS17725
uniprot id: D2PMS4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS10665
gene id: 479435:KFLA_RS10665
uniprot id: D2PSB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS05035
gene id: 479435:KFLA_RS05035
uniprot id: D2Q1E0
names: Similarity
messages: Belongs to the peptidase M1 family.

479435:KFLA RS30935
gene id: 479435:KFLA_RS30935
uniprot id: D2PVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS02990
gene id: 479435:KFLA_RS02990
uniprot id: D2PX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479435:KFLA RS06500
gene id: 479435:KFLA_RS06500
uniprot id: D2Q4A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS32150
gene id: 479435:KFLA_RS32150
uniprot id: D2PYA1
names: Similarity
messages: Belongs to the peptidase S13 family.

479435:KFLA RS06665
gene id: 479435:KFLA_RS06665
uniprot id: D2PKE0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21430
gene id: 479435:KFLA_RS21430
uniprot id: D2PV69
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

479435:KFLA RS12805
gene id: 479435:KFLA_RS12805
uniprot id: D2PXL6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

479435:KFLA RS30855
gene id: 479435:KFLA_RS30855
uniprot id: D2PVH4
names: Similarity
messages: Belongs to the UPF0234 family.

479435:KFLA RS30335
gene id: 479435:KFLA_RS30335
uniprot id: D2PU64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS06960
gene id: 479435:KFLA_RS06960
uniprot id: D2PKJ8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS03285
gene id: 479435:KFLA_RS03285
uniprot id: D2PXD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

479435:KFLA RS08230
gene id: 479435:KFLA_RS08230
uniprot id: D2PML8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS22995
gene id: 479435:KFLA_RS22995
uniprot id: D2PY57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS15305
gene id: 479435:KFLA_RS15305
uniprot id: D2Q328
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

479435:KFLA RS19575
gene id: 479435:KFLA_RS19575
uniprot id: D2PR43
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS33450
gene id: 479435:KFLA_RS33450
uniprot id: D2Q122
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS07730
gene id: 479435:KFLA_RS07730
uniprot id: D2PLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS20535
gene id: 479435:KFLA_RS20535
uniprot id: D2PSP1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

479435:KFLA RS21880
gene id: 479435:KFLA_RS21880
uniprot id: D2PWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

479435:KFLA RS11175
gene id: 479435:KFLA_RS11175
uniprot id: D2PTM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS07790
gene id: 479435:KFLA_RS07790
uniprot id: D2PMD3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS26115
gene id: 479435:KFLA_RS26115
uniprot id: D2PL26
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS29900
gene id: 479435:KFLA_RS29900
uniprot id: D2PSX6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

479435:KFLA RS25485
gene id: 479435:KFLA_RS25485
uniprot id: D2Q4Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS10350
gene id: 479435:KFLA_RS10350
uniprot id: D2PS55
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

479435:KFLA RS09910
gene id: 479435:KFLA_RS09910
uniprot id: D2PQW4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

479435:KFLA RS33155
gene id: 479435:KFLA_RS33155
uniprot id: D2Q0W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

479435:KFLA RS25800
gene id: 479435:KFLA_RS25800
uniprot id: D2Q4W4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

479435:KFLA RS23595
gene id: 479435:KFLA_RS23595
uniprot id: D2PZH0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

479435:KFLA RS26695
gene id: 479435:KFLA_RS26695
uniprot id: D2PM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS04985
gene id: 479435:KFLA_RS04985
uniprot id: D2Q1D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

479435:KFLA RS16885
gene id: 479435:KFLA_RS16885
uniprot id: D2PKZ2
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

479435:KFLA RS23860
gene id: 479435:KFLA_RS23860
uniprot id: D2Q0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS29045
gene id: 479435:KFLA_RS29045
uniprot id: D2PRD9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

479435:KFLA RS34440
gene id: 479435:KFLA_RS34440
uniprot id: D2Q3P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

479435:KFLA RS13630
gene id: 479435:KFLA_RS13630
uniprot id: D2PZ25
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

479435:KFLA RS03700
gene id: 479435:KFLA_RS03700
uniprot id: D2PYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

479435:KFLA RS25055
gene id: 479435:KFLA_RS25055
uniprot id: D2Q3E8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29540
gene id: 479435:KFLA_RS29540
uniprot id: D2PRN7
names: Similarity
messages: Belongs to the CutC family.

479435:KFLA RS28910
gene id: 479435:KFLA_RS28910
uniprot id: D2PQC7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

479435:KFLA RS15935
gene id: 479435:KFLA_RS15935
uniprot id: D2Q4G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

479435:KFLA RS14505
gene id: 479435:KFLA_RS14505
uniprot id: D2Q1K5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25535
gene id: 479435:KFLA_RS25535
uniprot id: D2Q4R1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

479435:KFLA RS04230
gene id: 479435:KFLA_RS04230
uniprot id: D2PZW5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

479435:KFLA RS00240
gene id: 479435:KFLA_RS00240
uniprot id: D2PQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS08740
gene id: 479435:KFLA_RS08740
uniprot id: D2PNL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS34400
gene id: 479435:KFLA_RS34400
uniprot id: D2Q3P0
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

479435:KFLA RS14895
gene id: 479435:KFLA_RS14895
uniprot id: D2Q1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

479435:KFLA RS33435
gene id: 479435:KFLA_RS33435
uniprot id: D2Q119
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS22325
gene id: 479435:KFLA_RS22325
uniprot id: D2PWQ9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23250
gene id: 479435:KFLA_RS23250
uniprot id: D2PZA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

479435:KFLA RS14275
gene id: 479435:KFLA_RS14275
uniprot id: D2Q0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

479435:KFLA RS06425
gene id: 479435:KFLA_RS06425
uniprot id: D2Q491
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS22150
gene id: 479435:KFLA_RS22150
uniprot id: D2PWM5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17740
gene id: 479435:KFLA_RS17740
uniprot id: D2PMS8
names: Similarity
messages: Belongs to the peptidase C40 family.

479435:KFLA RS27610
gene id: 479435:KFLA_RS27610
uniprot id: D2PN90
names: Subunit
messages: Homodimer.

479435:KFLA RS09840
gene id: 479435:KFLA_RS09840
uniprot id: D2PQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS05085
gene id: 479435:KFLA_RS05085
uniprot id: D2Q1F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

479435:KFLA RS12025
gene id: 479435:KFLA_RS12025
uniprot id: D2PW52
names: Similarity
messages: Belongs to the Fur family.

479435:KFLA RS05170
gene id: 479435:KFLA_RS05170
uniprot id: D2Q1G7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS04275
gene id: 479435:KFLA_RS04275
uniprot id: D2PZX4
names: Similarity
messages: Belongs to the peptidase S33 family.

479435:KFLA RS23620
gene id: 479435:KFLA_RS23620
uniprot id: D2PZH5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

479435:KFLA RS05955
gene id: 479435:KFLA_RS05955
uniprot id: D2Q2X9
names: Similarity
messages: Belongs to the SurE nucleotidase family.

479435:KFLA RS34190
gene id: 479435:KFLA_RS34190
uniprot id: D2Q2H2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

479435:KFLA RS14120
gene id: 479435:KFLA_RS14120
uniprot id: D2Q0C5
names: Similarity
messages: Belongs to the barstar family.

479435:KFLA RS23580
gene id: 479435:KFLA_RS23580
uniprot id: D2PZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

479435:KFLA RS01770
gene id: 479435:KFLA_RS01770
uniprot id: D2PUG3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS03095
gene id: 479435:KFLA_RS03095
uniprot id: D2PX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

479435:KFLA RS32310
gene id: 479435:KFLA_RS32310
uniprot id: D2PYD4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

479435:KFLA RS21095
gene id: 479435:KFLA_RS21095
uniprot id: D2PU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS30270
gene id: 479435:KFLA_RS30270
uniprot id: D2PU51
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

479435:KFLA RS25520
gene id: 479435:KFLA_RS25520
uniprot id: D2Q4Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

479435:KFLA RS20095
gene id: 479435:KFLA_RS20095
uniprot id: D2PSF5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS22910
gene id: 479435:KFLA_RS22910
uniprot id: D2PY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS33170
gene id: 479435:KFLA_RS33170
uniprot id: D2Q0W7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS28445
gene id: 479435:KFLA_RS28445
uniprot id: D2PQ36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

479435:KFLA RS01385
gene id: 479435:KFLA_RS01385
uniprot id: D2PT88
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS28885
gene id: 479435:KFLA_RS28885
uniprot id: D2PQC2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS26195
gene id: 479435:KFLA_RS26195
uniprot id: D2PL42
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

479435:KFLA RS29840
gene id: 479435:KFLA_RS29840
uniprot id: D2PSW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS04490
gene id: 479435:KFLA_RS04490
uniprot id: D2Q018
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

479435:KFLA RS06885
gene id: 479435:KFLA_RS06885
uniprot id: D2PKI3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

479435:KFLA RS12210
gene id: 479435:KFLA_RS12210
uniprot id: D2PW90
names: Similarity
messages: Belongs to the peptidase S9A family.

479435:KFLA RS33065
gene id: 479435:KFLA_RS33065
uniprot id: D2PZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS13750
gene id: 479435:KFLA_RS13750
uniprot id: D2PZ49
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

479435:KFLA RS12085
gene id: 479435:KFLA_RS12085
uniprot id: D2PW64
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS27855
gene id: 479435:KFLA_RS27855
uniprot id: D2PP26
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

479435:KFLA RS11885
gene id: 479435:KFLA_RS11885
uniprot id: D2PV10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

479435:KFLA RS15185
gene id: 479435:KFLA_RS15185
uniprot id: D2Q305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

479435:KFLA RS22315
gene id: 479435:KFLA_RS22315
uniprot id: D2PWQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

479435:KFLA RS29805
gene id: 479435:KFLA_RS29805
uniprot id: D2PSV6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

479435:KFLA RS10640
gene id: 479435:KFLA_RS10640
uniprot id: D2PSB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS05140
gene id: 479435:KFLA_RS05140
uniprot id: D2Q1G1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS03035
gene id: 479435:KFLA_RS03035
uniprot id: D2PX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

479435:KFLA RS24400
gene id: 479435:KFLA_RS24400
uniprot id: D2Q1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

479435:KFLA RS25470
gene id: 479435:KFLA_RS25470
uniprot id: D2Q4P8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

479435:KFLA RS29165
gene id: 479435:KFLA_RS29165
uniprot id: D2PRG3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

479435:KFLA RS22380
gene id: 479435:KFLA_RS22380
uniprot id: D2PWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS14470
gene id: 479435:KFLA_RS14470
uniprot id: D2Q1J8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

479435:KFLA RS21675
gene id: 479435:KFLA_RS21675
uniprot id: D2PVC0
names: Similarity
messages: Belongs to the peptidase A24 family.

479435:KFLA RS11325
gene id: 479435:KFLA_RS11325
uniprot id: D2PTQ4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

479435:KFLA RS00710
gene id: 479435:KFLA_RS00710
uniprot id: D2PRU0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

479435:KFLA RS29005
gene id: 479435:KFLA_RS29005
uniprot id: D2PRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479435:KFLA RS32995
gene id: 479435:KFLA_RS32995
uniprot id: D2PZR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

479435:KFLA RS33670
gene id: 479435:KFLA_RS33670
uniprot id: D2Q165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS12925
gene id: 479435:KFLA_RS12925
uniprot id: D2PXP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS18090
gene id: 479435:KFLA_RS18090
uniprot id: D2PMZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS17390
gene id: 479435:KFLA_RS17390
uniprot id: D2PLX7
names: Similarity
messages: Belongs to the peptidase M1 family.

479435:KFLA RS09040
gene id: 479435:KFLA_RS09040
uniprot id: D2PPG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

479435:KFLA RS31220
gene id: 479435:KFLA_RS31220
uniprot id: D2PVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

479435:KFLA RS06810
gene id: 479435:KFLA_RS06810
uniprot id: D2PKG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS13385
gene id: 479435:KFLA_RS13385
uniprot id: D2PYX6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS21720
gene id: 479435:KFLA_RS21720
uniprot id: D2PVC9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

479435:KFLA RS10905
gene id: 479435:KFLA_RS10905
uniprot id: D2PTH4
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS06260
gene id: 479435:KFLA_RS06260
uniprot id: D2Q457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS14150
gene id: 479435:KFLA_RS14150
uniprot id: D2Q0D1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

479435:KFLA RS17870
gene id: 479435:KFLA_RS17870
uniprot id: D2PMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

479435:KFLA RS30300
gene id: 479435:KFLA_RS30300
uniprot id: D2PU57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

479435:KFLA RS23780
gene id: 479435:KFLA_RS23780
uniprot id: D2Q0L6
names: Similarity
messages: Belongs to the threonine aldolase family.

479435:KFLA RS10500
gene id: 479435:KFLA_RS10500
uniprot id: D2PS84
names: Similarity
messages: Belongs to the TPP enzyme family.

479435:KFLA RS28415
gene id: 479435:KFLA_RS28415
uniprot id: D2PPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

479435:KFLA RS17250
gene id: 479435:KFLA_RS17250
uniprot id: D2PLU9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS20930
gene id: 479435:KFLA_RS20930
uniprot id: D2PTX2
names: Similarity
messages: Belongs to the manganese catalase family.

479435:KFLA RS19955
gene id: 479435:KFLA_RS19955
uniprot id: D2PRB7
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

479435:KFLA RS30360
gene id: 479435:KFLA_RS30360
uniprot id: D2PU69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

479435:KFLA RS14635
gene id: 479435:KFLA_RS14635
uniprot id: D2Q1N0
names: Similarity
messages: Belongs to the peptidase M16 family.

479435:KFLA RS24080
gene id: 479435:KFLA_RS24080
uniprot id: D2Q0S5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

479435:KFLA RS07385
gene id: 479435:KFLA_RS07385
uniprot id: D2PLG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS11500
gene id: 479435:KFLA_RS11500
uniprot id: D2PUT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

479435:KFLA RS08935
gene id: 479435:KFLA_RS08935
uniprot id: D2PPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS31270
gene id: 479435:KFLA_RS31270
uniprot id: D2PVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS03835
gene id: 479435:KFLA_RS03835
uniprot id: D2PYP2
names: Function
names: Similarity
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
messages: Belongs to the peptidase S45 family.

479435:KFLA RS17635
gene id: 479435:KFLA_RS17635
uniprot id: D2PMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS30200
gene id: 479435:KFLA_RS30200
uniprot id: D2PU37
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

479435:KFLA RS28890
gene id: 479435:KFLA_RS28890
uniprot id: D2PQC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

479435:KFLA RS18330
gene id: 479435:KFLA_RS18330
uniprot id: D2PNS8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

479435:KFLA RS03770
gene id: 479435:KFLA_RS03770
uniprot id: D2PYM9
names: Similarity
messages: Belongs to the EccD/Snm4 family.

479435:KFLA RS29635
gene id: 479435:KFLA_RS29635
uniprot id: D2PSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

479435:KFLA RS29595
gene id: 479435:KFLA_RS29595
uniprot id: D2PRP8
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS20195
gene id: 479435:KFLA_RS20195
uniprot id: D2PSH5
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17240
gene id: 479435:KFLA_RS17240
uniprot id: D2PLU7
names: Similarity
messages: Belongs to the peptidase S58 family.

479435:KFLA RS04950
gene id: 479435:KFLA_RS04950
uniprot id: D2Q1C3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS03305
gene id: 479435:KFLA_RS03305
uniprot id: D2PXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS35110
gene id: 479435:KFLA_RS35110
uniprot id: D2Q543
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23365
gene id: 479435:KFLA_RS23365
uniprot id: D2PZC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS13920
gene id: 479435:KFLA_RS13920
uniprot id: D2Q085
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS33965
gene id: 479435:KFLA_RS33965
uniprot id: D2Q2C8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS13455
gene id: 479435:KFLA_RS13455
uniprot id: D2PYZ0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

479435:KFLA RS03855
gene id: 479435:KFLA_RS03855
uniprot id: D2PYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS30015
gene id: 479435:KFLA_RS30015
uniprot id: D2PSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

479435:KFLA RS25830
gene id: 479435:KFLA_RS25830
uniprot id: D2Q4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

479435:KFLA RS33050
gene id: 479435:KFLA_RS33050
uniprot id: D2PZS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

479435:KFLA RS29745
gene id: 479435:KFLA_RS29745
uniprot id: D2PSU4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS17155
gene id: 479435:KFLA_RS17155
uniprot id: D2PLT0
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

479435:KFLA RS14675
gene id: 479435:KFLA_RS14675
uniprot id: D2Q1N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

479435:KFLA RS09855
gene id: 479435:KFLA_RS09855
uniprot id: D2PQV3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS36150
gene id: 479435:KFLA_RS36150
uniprot id: D2PRS9
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS24585
gene id: 479435:KFLA_RS24585
uniprot id: D2Q230
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

479435:KFLA RS21625
gene id: 479435:KFLA_RS21625
uniprot id: D2PVB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

479435:KFLA RS00750
gene id: 479435:KFLA_RS00750
uniprot id: D2PRU8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS31710
gene id: 479435:KFLA_RS31710
uniprot id: D2PX01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS05950
gene id: 479435:KFLA_RS05950
uniprot id: D2Q2X8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

479435:KFLA RS26400
gene id: 479435:KFLA_RS26400
uniprot id: D2PL84
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25970
gene id: 479435:KFLA_RS25970
uniprot id: D2Q4Z7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

479435:KFLA RS13755
gene id: 479435:KFLA_RS13755
uniprot id: D2PZ50
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

479435:KFLA RS28285
gene id: 479435:KFLA_RS28285
uniprot id: D2PPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

479435:KFLA RS19935
gene id: 479435:KFLA_RS19935
uniprot id: D2PRB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS26500
gene id: 479435:KFLA_RS26500
uniprot id: D2PLA6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

479435:KFLA RS11990
gene id: 479435:KFLA_RS11990
uniprot id: D2PV31
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS34780
gene id: 479435:KFLA_RS34780
uniprot id: D2Q3W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

479435:KFLA RS02925
gene id: 479435:KFLA_RS02925
uniprot id: D2PX60
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

479435:KFLA RS10945
gene id: 479435:KFLA_RS10945
uniprot id: D2PTI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS27735
gene id: 479435:KFLA_RS27735
uniprot id: D2PNB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

479435:KFLA RS07785
gene id: 479435:KFLA_RS07785
uniprot id: D2PMD2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS23490
gene id: 479435:KFLA_RS23490
uniprot id: D2PZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

479435:KFLA RS22375
gene id: 479435:KFLA_RS22375
uniprot id: D2PWR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS30495
gene id: 479435:KFLA_RS30495
uniprot id: D2PU95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

479435:KFLA RS31565
gene id: 479435:KFLA_RS31565
uniprot id: D2PWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS29530
gene id: 479435:KFLA_RS29530
uniprot id: D2PRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

479435:KFLA RS25460
gene id: 479435:KFLA_RS25460
uniprot id: D2Q4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

479435:KFLA RS07565
gene id: 479435:KFLA_RS07565
uniprot id: D2PLK3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS11540
gene id: 479435:KFLA_RS11540
uniprot id: D2PUU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

479435:KFLA RS14620
gene id: 479435:KFLA_RS14620
uniprot id: D2Q1M7
names: Similarity
messages: Belongs to the ribF family.

479435:KFLA RS26720
gene id: 479435:KFLA_RS26720
uniprot id: D2PM37
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

479435:KFLA RS29830
gene id: 479435:KFLA_RS29830
uniprot id: D2PSW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS13880
gene id: 479435:KFLA_RS13880
uniprot id: D2Q077
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

479435:KFLA RS16275
gene id: 479435:KFLA_RS16275
uniprot id: D2Q4M9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

479435:KFLA RS23480
gene id: 479435:KFLA_RS23480
uniprot id: D2PZE7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

479435:KFLA RS30700
gene id: 479435:KFLA_RS30700
uniprot id: D2PUD5
names: Similarity
messages: Belongs to the UPF0336 family.

479435:KFLA RS13605
gene id: 479435:KFLA_RS13605
uniprot id: D2PZ20
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS32010
gene id: 479435:KFLA_RS32010
uniprot id: D2PY73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS20745
gene id: 479435:KFLA_RS20745
uniprot id: D2PTT8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS29815
gene id: 479435:KFLA_RS29815
uniprot id: D2PSV8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS30285
gene id: 479435:KFLA_RS30285
uniprot id: D2PU54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

479435:KFLA RS02720
gene id: 479435:KFLA_RS02720
uniprot id: D2PW09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

479435:KFLA RS06275
gene id: 479435:KFLA_RS06275
uniprot id: D2Q461
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

479435:KFLA RS21280
gene id: 479435:KFLA_RS21280
uniprot id: D2PV42
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS16180
gene id: 479435:KFLA_RS16180
uniprot id: D2Q4L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

479435:KFLA RS33350
gene id: 479435:KFLA_RS33350
uniprot id: D2Q103
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24050
gene id: 479435:KFLA_RS24050
uniprot id: D2Q0R9
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

479435:KFLA RS16160
gene id: 479435:KFLA_RS16160
uniprot id: D2Q4K6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS22030
gene id: 479435:KFLA_RS22030
uniprot id: D2PWK2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS32610
gene id: 479435:KFLA_RS32610
uniprot id: D2PZJ5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

479435:KFLA RS33405
gene id: 479435:KFLA_RS33405
uniprot id: D2Q113
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

479435:KFLA RS27690
gene id: 479435:KFLA_RS27690
uniprot id: D2PNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS03690
gene id: 479435:KFLA_RS03690
uniprot id: D2PYL4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

479435:KFLA RS35190
gene id: 479435:KFLA_RS35190
uniprot id: D2Q561
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

479435:KFLA RS32370
gene id: 479435:KFLA_RS32370
uniprot id: D2PYE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479435:KFLA RS30375
gene id: 479435:KFLA_RS30375
uniprot id: D2PU72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

479435:KFLA RS18670
gene id: 479435:KFLA_RS18670
uniprot id: D2PNZ6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

479435:KFLA RS33665
gene id: 479435:KFLA_RS33665
uniprot id: D2Q164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS23950
gene id: 479435:KFLA_RS23950
uniprot id: D2Q0Q0
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS24975
gene id: 479435:KFLA_RS24975
uniprot id: D2Q3D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS06130
gene id: 479435:KFLA_RS06130
uniprot id: D2Q431
names: Similarity
messages: Belongs to the peptidase C1 family.

479435:KFLA RS13465
gene id: 479435:KFLA_RS13465
uniprot id: D2PYZ2
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

479435:KFLA RS00285
gene id: 479435:KFLA_RS00285
uniprot id: D2PQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

479435:KFLA RS11955
gene id: 479435:KFLA_RS11955
uniprot id: D2PV24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

479435:KFLA RS15795
gene id: 479435:KFLA_RS15795
uniprot id: D2Q4D7
names: Similarity
messages: Belongs to the peptidase U62 family.

479435:KFLA RS14300
gene id: 479435:KFLA_RS14300
uniprot id: D2Q0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

479435:KFLA RS21060
gene id: 479435:KFLA_RS21060
uniprot id: D2PTZ8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

479435:KFLA RS20135
gene id: 479435:KFLA_RS20135
uniprot id: D2PSG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

479435:KFLA RS13495
gene id: 479435:KFLA_RS13495
uniprot id: D2PYZ8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS28575
gene id: 479435:KFLA_RS28575
uniprot id: D2PQ62
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS18930
gene id: 479435:KFLA_RS18930
uniprot id: D2PPU0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

479435:KFLA RS21980
gene id: 479435:KFLA_RS21980
uniprot id: D2PWJ2
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

479435:KFLA RS26075
gene id: 479435:KFLA_RS26075
uniprot id: D2PL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS06175
gene id: 479435:KFLA_RS06175
uniprot id: D2Q440
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS21695
gene id: 479435:KFLA_RS21695
uniprot id: D2PVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

479435:KFLA RS15435
gene id: 479435:KFLA_RS15435
uniprot id: D2Q355
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

479435:KFLA RS00415
gene id: 479435:KFLA_RS00415
uniprot id: D2PQM4
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

479435:KFLA RS05205
gene id: 479435:KFLA_RS05205
uniprot id: D2Q1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

479435:KFLA RS31175
gene id: 479435:KFLA_RS31175
uniprot id: D2PVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

479435:KFLA RS04955
gene id: 479435:KFLA_RS04955
uniprot id: D2Q1C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

479435:KFLA RS05270
gene id: 479435:KFLA_RS05270
uniprot id: D2Q1I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

479435:KFLA RS02555
gene id: 479435:KFLA_RS02555
uniprot id: D2PVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

479435:KFLA RS07955
gene id: 479435:KFLA_RS07955
uniprot id: D2PMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS16040
gene id: 479435:KFLA_RS16040
uniprot id: D2Q4I5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

479435:KFLA RS18445
gene id: 479435:KFLA_RS18445
uniprot id: D2PNV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

479435:KFLA RS24405
gene id: 479435:KFLA_RS24405
uniprot id: D2Q1Z3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

479435:KFLA RS20625
gene id: 479435:KFLA_RS20625
uniprot id: D2PSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS06420
gene id: 479435:KFLA_RS06420
uniprot id: D2Q490
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

479435:KFLA RS16490
gene id: 479435:KFLA_RS16490
uniprot id: D2PKS1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

479435:KFLA RS13265
gene id: 479435:KFLA_RS13265
uniprot id: D2PYV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS22285
gene id: 479435:KFLA_RS22285
uniprot id: D2PWQ2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21505
gene id: 479435:KFLA_RS21505
uniprot id: D2PV86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

479435:KFLA RS18250
gene id: 479435:KFLA_RS18250
uniprot id: D2PNR2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

479435:KFLA RS26865
gene id: 479435:KFLA_RS26865
uniprot id: D2PM65
names: Similarity
messages: Belongs to the TlyA family.

479435:KFLA RS28980
gene id: 479435:KFLA_RS28980
uniprot id: D2PQE2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

479435:KFLA RS12505
gene id: 479435:KFLA_RS12505
uniprot id: D2PWE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

479435:KFLA RS21865
gene id: 479435:KFLA_RS21865
uniprot id: D2PVF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

479435:KFLA RS27895
gene id: 479435:KFLA_RS27895
uniprot id: D2PP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS29825
gene id: 479435:KFLA_RS29825
uniprot id: D2PSW1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

479435:KFLA RS13795
gene id: 479435:KFLA_RS13795
uniprot id: D2PZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

479435:KFLA RS11730
gene id: 479435:KFLA_RS11730
uniprot id: D2PUY0
names: Similarity
messages: Belongs to the UPF0047 family.

479435:KFLA RS25170
gene id: 479435:KFLA_RS25170
uniprot id: D2Q3H0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS22930
gene id: 479435:KFLA_RS22930
uniprot id: D2PY43
names: Similarity
messages: Belongs to the HIBADH-related family.

479435:KFLA RS03415
gene id: 479435:KFLA_RS03415
uniprot id: D2PXF8
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15775
gene id: 479435:KFLA_RS15775
uniprot id: D2Q4D3
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

479435:KFLA RS24290
gene id: 479435:KFLA_RS24290
uniprot id: D2Q1X0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

479435:KFLA RS18425
gene id: 479435:KFLA_RS18425
uniprot id: D2PNU7
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

479435:KFLA RS16930
gene id: 479435:KFLA_RS16930
uniprot id: D2PL00
names: Similarity
messages: Belongs to the group II decarboxylase family.

479435:KFLA RS24355
gene id: 479435:KFLA_RS24355
uniprot id: D2Q1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS33475
gene id: 479435:KFLA_RS33475
uniprot id: D2Q127
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

479435:KFLA RS17860
gene id: 479435:KFLA_RS17860
uniprot id: D2PMV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

479435:KFLA RS32445
gene id: 479435:KFLA_RS32445
uniprot id: D2PYG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

479435:KFLA RS09825
gene id: 479435:KFLA_RS09825
uniprot id: D2PQU7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

479435:KFLA RS19985
gene id: 479435:KFLA_RS19985
uniprot id: D2PRC3
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS18885
gene id: 479435:KFLA_RS18885
uniprot id: D2PPT1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS27670
gene id: 479435:KFLA_RS27670
uniprot id: D2PNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

479435:KFLA RS31255
gene id: 479435:KFLA_RS31255
uniprot id: D2PVQ6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

479435:KFLA RS33960
gene id: 479435:KFLA_RS33960
uniprot id: D2Q2C7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS01665
gene id: 479435:KFLA_RS01665
uniprot id: D2PTE3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS25030
gene id: 479435:KFLA_RS25030
uniprot id: D2Q3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

479435:KFLA RS03805
gene id: 479435:KFLA_RS03805
uniprot id: D2PYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS33495
gene id: 479435:KFLA_RS33495
uniprot id: D2Q131
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS23775
gene id: 479435:KFLA_RS23775
uniprot id: D2Q0L5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS31010
gene id: 479435:KFLA_RS31010
uniprot id: D2PVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

479435:KFLA RS09370
gene id: 479435:KFLA_RS09370
uniprot id: D2PPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Cytoplasm
messages: Involved in the intracellular degradation of the cyclic tetrasaccharide cyclobis-(1-6)-alpha-nigerosyl (CNN) formed extracellularly from starch. Catalyzes the hydrolysis of the alpha-1,3-glucosidic linkage of cyclobis-(1-6)-alpha-nigerosyl (CNN) to yield isomaltose via a possible linear tetrasaccharide. It has a strong preference for the alpha-(1-3)-isomaltosyl moiety.

479435:KFLA RS28695
gene id: 479435:KFLA_RS28695
uniprot id: D2PQ84
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS18230
gene id: 479435:KFLA_RS18230
uniprot id: D2PNQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

479435:KFLA RS17690
gene id: 479435:KFLA_RS17690
uniprot id: D2PMR7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS03240
gene id: 479435:KFLA_RS03240
uniprot id: D2PXC6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

479435:KFLA RS30155
gene id: 479435:KFLA_RS30155
uniprot id: D2PT27
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

479435:KFLA RS21595
gene id: 479435:KFLA_RS21595
uniprot id: D2PVA4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

479435:KFLA RS08785
gene id: 479435:KFLA_RS08785
uniprot id: D2PNM3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

479435:KFLA RS14110
gene id: 479435:KFLA_RS14110
uniprot id: D2Q0C3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS29485
gene id: 479435:KFLA_RS29485
uniprot id: D2PRM6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14575
gene id: 479435:KFLA_RS14575
uniprot id: D2Q1L8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

479435:KFLA RS30975
gene id: 479435:KFLA_RS30975
uniprot id: D2PVJ8
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS07765
gene id: 479435:KFLA_RS07765
uniprot id: D2PLP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

479435:KFLA RS10450
gene id: 479435:KFLA_RS10450
uniprot id: D2PS74
names: Similarity
messages: Belongs to the AOR/FOR family.

479435:KFLA RS14320
gene id: 479435:KFLA_RS14320
uniprot id: D2Q0G4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

479435:KFLA RS26375
gene id: 479435:KFLA_RS26375
uniprot id: D2PL79
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS17720
gene id: 479435:KFLA_RS17720
uniprot id: D2PMS3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15685
gene id: 479435:KFLA_RS15685
uniprot id: D2Q3A4
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS28930
gene id: 479435:KFLA_RS28930
uniprot id: D2PQD1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS30440
gene id: 479435:KFLA_RS30440
uniprot id: D2PU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

479435:KFLA RS06045
gene id: 479435:KFLA_RS06045
uniprot id: D2Q414
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

479435:KFLA RS04630
gene id: 479435:KFLA_RS04630
uniprot id: D2Q048
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

479435:KFLA RS06215
gene id: 479435:KFLA_RS06215
uniprot id: D2Q448
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS19840
gene id: 479435:KFLA_RS19840
uniprot id: D2PR95
names: Similarity
messages: Belongs to the type IB topoisomerase family.

479435:KFLA RS14395
gene id: 479435:KFLA_RS14395
uniprot id: D2Q0H9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS21900
gene id: 479435:KFLA_RS21900
uniprot id: D2PWH6
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS10415
gene id: 479435:KFLA_RS10415
uniprot id: D2PS67
names: Subcellular Location Annotation
messages: Cytoplasm

479435:KFLA RS03105
gene id: 479435:KFLA_RS03105
uniprot id: D2PX97
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

479435:KFLA RS31265
gene id: 479435:KFLA_RS31265
uniprot id: D2PVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS31775
gene id: 479435:KFLA_RS31775
uniprot id: D2PX15
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

479435:KFLA RS35140
gene id: 479435:KFLA_RS35140
uniprot id: D2Q550
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

479435:KFLA RS02060
gene id: 479435:KFLA_RS02060
uniprot id: D2PUL8
names: Similarity
messages: Belongs to the Fur family.

479435:KFLA RS27075
gene id: 479435:KFLA_RS27075
uniprot id: D2PMA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

479435:KFLA RS16980
gene id: 479435:KFLA_RS16980
uniprot id: D2PL08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS23065
gene id: 479435:KFLA_RS23065
uniprot id: D2PY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS28740
gene id: 479435:KFLA_RS28740
uniprot id: D2PQ92
names: Similarity
messages: Belongs to the YciI family.

479435:KFLA RS29155
gene id: 479435:KFLA_RS29155
uniprot id: D2PRG1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS01625
gene id: 479435:KFLA_RS01625
uniprot id: D2PTD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

479435:KFLA RS17425
gene id: 479435:KFLA_RS17425
uniprot id: D2PLY4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS35820
gene id: 479435:KFLA_RS35820
uniprot id: D2PV43
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS23300
gene id: 479435:KFLA_RS23300
uniprot id: D2PZB1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

479435:KFLA RS30390
gene id: 479435:KFLA_RS30390
uniprot id: D2PU75
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

479435:KFLA RS23865
gene id: 479435:KFLA_RS23865
uniprot id: D2Q0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS23030
gene id: 479435:KFLA_RS23030
uniprot id: D2PY63
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

479435:KFLA RS27025
gene id: 479435:KFLA_RS27025
uniprot id: D2PM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

479435:KFLA RS24010
gene id: 479435:KFLA_RS24010
uniprot id: D2Q0R1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS10550
gene id: 479435:KFLA_RS10550
uniprot id: D2PS94
names: Similarity
messages: Belongs to the HIBADH-related family.

479435:KFLA RS06080
gene id: 479435:KFLA_RS06080
uniprot id: D2Q421
names: Subcellular Location Annotation
messages: Cytoplasm

479435:KFLA RS27285
gene id: 479435:KFLA_RS27285
uniprot id: D2PN27
names: Similarity
messages: Belongs to the peptidase M17 family.

479435:KFLA RS14095
gene id: 479435:KFLA_RS14095
uniprot id: D2Q0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

479435:KFLA RS18395
gene id: 479435:KFLA_RS18395
uniprot id: D2PNU1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

479435:KFLA RS21845
gene id: 479435:KFLA_RS21845
uniprot id: D2PVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

479435:KFLA RS02825
gene id: 479435:KFLA_RS02825
uniprot id: D2PW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS13860
gene id: 479435:KFLA_RS13860
uniprot id: D2Q073
names: Similarity
messages: Belongs to the peptidase C40 family.

479435:KFLA RS26705
gene id: 479435:KFLA_RS26705
uniprot id: D2PM34
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

479435:KFLA RS34935
gene id: 479435:KFLA_RS34935
uniprot id: D2Q3Z6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

479435:KFLA RS28320
gene id: 479435:KFLA_RS28320
uniprot id: D2PPB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS13335
gene id: 479435:KFLA_RS13335
uniprot id: D2PYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS21790
gene id: 479435:KFLA_RS21790
uniprot id: D2PVE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS13395
gene id: 479435:KFLA_RS13395
uniprot id: D2PYX8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

479435:KFLA RS32415
gene id: 479435:KFLA_RS32415
uniprot id: D2PYF5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

479435:KFLA RS09125
gene id: 479435:KFLA_RS09125
uniprot id: D2PPI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

479435:KFLA RS00895
gene id: 479435:KFLA_RS00895
uniprot id: D2PRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

479435:KFLA RS15190
gene id: 479435:KFLA_RS15190
uniprot id: D2Q306
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

479435:KFLA RS01200
gene id: 479435:KFLA_RS01200
uniprot id: D2PT52
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479435:KFLA RS32845
gene id: 479435:KFLA_RS32845
uniprot id: D2PZP0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS26235
gene id: 479435:KFLA_RS26235
uniprot id: D2PL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS17435
gene id: 479435:KFLA_RS17435
uniprot id: D2PLY6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS02725
gene id: 479435:KFLA_RS02725
uniprot id: D2PW10
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

479435:KFLA RS31005
gene id: 479435:KFLA_RS31005
uniprot id: D2PVK4
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS22575
gene id: 479435:KFLA_RS22575
uniprot id: D2PXW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS06840
gene id: 479435:KFLA_RS06840
uniprot id: D2PKH4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS34710
gene id: 479435:KFLA_RS34710
uniprot id: D2Q3V1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09200
gene id: 479435:KFLA_RS09200
uniprot id: D2PPJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS00205
gene id: 479435:KFLA_RS00205
uniprot id: D2PQI3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29860
gene id: 479435:KFLA_RS29860
uniprot id: D2PSW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS21680
gene id: 479435:KFLA_RS21680
uniprot id: D2PVC1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479435:KFLA RS27505
gene id: 479435:KFLA_RS27505
uniprot id: D2PN70
names: Similarity
messages: Belongs to the cytochrome P450 family.

479435:KFLA RS29925
gene id: 479435:KFLA_RS29925
uniprot id: D2PSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

479435:KFLA RS33260
gene id: 479435:KFLA_RS33260
uniprot id: D2Q0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS11510
gene id: 479435:KFLA_RS11510
uniprot id: D2PUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

479435:KFLA RS38110
gene id: 479435:KFLA_RS38110
uniprot id: D2PRQ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS15430
gene id: 479435:KFLA_RS15430
uniprot id: D2Q354
names: Similarity
messages: Belongs to the peptidase C40 family.

479435:KFLA RS23815
gene id: 479435:KFLA_RS23815
uniprot id: D2Q0M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

479435:KFLA RS30025
gene id: 479435:KFLA_RS30025
uniprot id: D2PT01
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS24595
gene id: 479435:KFLA_RS24595
uniprot id: D2Q232
names: Similarity
messages: Belongs to the citrate synthase family.

479435:KFLA RS16235
gene id: 479435:KFLA_RS16235
uniprot id: D2Q4M1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS29920
gene id: 479435:KFLA_RS29920
uniprot id: D2PSY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

479435:KFLA RS34505
gene id: 479435:KFLA_RS34505
uniprot id: D2Q3R0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

479435:KFLA RS07580
gene id: 479435:KFLA_RS07580
uniprot id: D2PLK6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

479435:KFLA RS16485
gene id: 479435:KFLA_RS16485
uniprot id: D2PKR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

479435:KFLA RS21560
gene id: 479435:KFLA_RS21560
uniprot id: D2PV97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

479435:KFLA RS23540
gene id: 479435:KFLA_RS23540
uniprot id: D2PZF9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

479435:KFLA RS24270
gene id: 479435:KFLA_RS24270
uniprot id: D2Q0W2
names: Similarity
messages: Belongs to the CFA/CMAS family.

479435:KFLA RS10660
gene id: 479435:KFLA_RS10660
uniprot id: D2PSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS00560
gene id: 479435:KFLA_RS00560
uniprot id: D2PRR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS24185
gene id: 479435:KFLA_RS24185
uniprot id: D2Q0U4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

479435:KFLA RS28240
gene id: 479435:KFLA_RS28240
uniprot id: D2PPA2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

479435:KFLA RS08540
gene id: 479435:KFLA_RS08540
uniprot id: D2PNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS29240
gene id: 479435:KFLA_RS29240
uniprot id: D2PRH7
names: Similarity
messages: Belongs to the citrate synthase family.

479435:KFLA RS26940
gene id: 479435:KFLA_RS26940
uniprot id: D2PM76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

479435:KFLA RS18630
gene id: 479435:KFLA_RS18630
uniprot id: D2PNY8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS24835
gene id: 479435:KFLA_RS24835
uniprot id: D2Q281
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

479435:KFLA RS24360
gene id: 479435:KFLA_RS24360
uniprot id: D2Q1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS34270
gene id: 479435:KFLA_RS34270
uniprot id: D2Q2I9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

479435:KFLA RS15425
gene id: 479435:KFLA_RS15425
uniprot id: D2Q353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

479435:KFLA RS02025
gene id: 479435:KFLA_RS02025
uniprot id: D2PUL1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

479435:KFLA RS31675
gene id: 479435:KFLA_RS31675
uniprot id: D2PWZ6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

479435:KFLA RS27160
gene id: 479435:KFLA_RS27160
uniprot id: D2PMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

479435:KFLA RS31330
gene id: 479435:KFLA_RS31330
uniprot id: D2PVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS13820
gene id: 479435:KFLA_RS13820
uniprot id: D2PZ63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS19115
gene id: 479435:KFLA_RS19115
uniprot id: D2PPX7
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS14555
gene id: 479435:KFLA_RS14555
uniprot id: D2Q1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

479435:KFLA RS03170
gene id: 479435:KFLA_RS03170
uniprot id: D2PXB0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS20935
gene id: 479435:KFLA_RS20935
uniprot id: D2PTX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

479435:KFLA RS02185
gene id: 479435:KFLA_RS02185
uniprot id: D2PUP2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

479435:KFLA RS03390
gene id: 479435:KFLA_RS03390
uniprot id: D2PXF3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

479435:KFLA RS05265
gene id: 479435:KFLA_RS05265
uniprot id: D2Q1I6
names: Similarity
messages: Belongs to the UPF0145 family.

479435:KFLA RS30655
gene id: 479435:KFLA_RS30655
uniprot id: D2PUC6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

479435:KFLA RS02205
gene id: 479435:KFLA_RS02205
uniprot id: D2PUP6
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

479435:KFLA RS00025
gene id: 479435:KFLA_RS00025
uniprot id: D2PQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

479435:KFLA RS24995
gene id: 479435:KFLA_RS24995
uniprot id: D2Q3D6
names: Similarity
messages: Belongs to the peptidase S49 family.

479435:KFLA RS28015
gene id: 479435:KFLA_RS28015
uniprot id: D2PP58
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

479435:KFLA RS35400
gene id: 479435:KFLA_RS35400
uniprot id: D2PKH9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS09635
gene id: 479435:KFLA_RS09635
uniprot id: D2PQR2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

479435:KFLA RS32130
gene id: 479435:KFLA_RS32130
uniprot id: D2PY97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

479435:KFLA RS07690
gene id: 479435:KFLA_RS07690
uniprot id: D2PLM8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

479435:KFLA RS31340
gene id: 479435:KFLA_RS31340
uniprot id: D2PVS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

479435:KFLA RS34095
gene id: 479435:KFLA_RS34095
uniprot id: D2Q2F4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

479435:KFLA RS21700
gene id: 479435:KFLA_RS21700
uniprot id: D2PVC5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

479435:KFLA RS24255
gene id: 479435:KFLA_RS24255
uniprot id: D2Q0V9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479435:KFLA RS22080
gene id: 479435:KFLA_RS22080
uniprot id: D2PWL2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

479435:KFLA RS19230
gene id: 479435:KFLA_RS19230
uniprot id: D2PQ00
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06505
gene id: 479435:KFLA_RS06505
uniprot id: D2Q4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS03935
gene id: 479435:KFLA_RS03935
uniprot id: D2PYR2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

479435:KFLA RS27635
gene id: 479435:KFLA_RS27635
uniprot id: D2PN95
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

479435:KFLA RS30565
gene id: 479435:KFLA_RS30565
uniprot id: D2PUA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

479435:KFLA RS04735
gene id: 479435:KFLA_RS04735
uniprot id: D2Q069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

479435:KFLA RS03055
gene id: 479435:KFLA_RS03055
uniprot id: D2PX87
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479435:KFLA RS27245
gene id: 479435:KFLA_RS27245
uniprot id: D2PN20
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

479435:KFLA RS01685
gene id: 479435:KFLA_RS01685
uniprot id: D2PTE7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS16060
gene id: 479435:KFLA_RS16060
uniprot id: D2Q4I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

479435:KFLA RS24910
gene id: 479435:KFLA_RS24910
uniprot id: D2Q3B9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

479435:KFLA RS25885
gene id: 479435:KFLA_RS25885
uniprot id: D2Q4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

479435:KFLA RS20560
gene id: 479435:KFLA_RS20560
uniprot id: D2PSP6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25065
gene id: 479435:KFLA_RS25065
uniprot id: D2Q3F0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

479435:KFLA RS29255
gene id: 479435:KFLA_RS29255
uniprot id: D2PRI0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS31295
gene id: 479435:KFLA_RS31295
uniprot id: D2PVR4
names: Similarity
messages: Belongs to the isochorismate synthase family.

479435:KFLA RS24385
gene id: 479435:KFLA_RS24385
uniprot id: D2Q1Y9
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

479435:KFLA RS33595
gene id: 479435:KFLA_RS33595
uniprot id: D2Q151
names: Similarity
messages: Belongs to the peptidase S8 family.

479435:KFLA RS32665
gene id: 479435:KFLA_RS32665
uniprot id: D2PZK6
names: Similarity
messages: Belongs to the DinB family.

479435:KFLA RS24630
gene id: 479435:KFLA_RS24630
uniprot id: D2Q239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS32270
gene id: 479435:KFLA_RS32270
uniprot id: D2PYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

479435:KFLA RS13360
gene id: 479435:KFLA_RS13360
uniprot id: D2PYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

479435:KFLA RS06600
gene id: 479435:KFLA_RS06600
uniprot id: D2PKC7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

479435:KFLA RS33440
gene id: 479435:KFLA_RS33440
uniprot id: D2Q120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

479435:KFLA RS27010
gene id: 479435:KFLA_RS27010
uniprot id: D2PM90
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

479435:KFLA RS32660
gene id: 479435:KFLA_RS32660
uniprot id: D2PZK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

479435:KFLA RS17855
gene id: 479435:KFLA_RS17855
uniprot id: D2PMV1
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS20710
gene id: 479435:KFLA_RS20710
uniprot id: D2PTT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

479435:KFLA RS17015
gene id: 479435:KFLA_RS17015
uniprot id: D2PLQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

479435:KFLA RS07140
gene id: 479435:KFLA_RS07140
uniprot id: D2PKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

479435:KFLA RS13810
gene id: 479435:KFLA_RS13810
uniprot id: D2PZ61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

479435:KFLA RS01610
gene id: 479435:KFLA_RS01610
uniprot id: D2PTD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS33645
gene id: 479435:KFLA_RS33645
uniprot id: D2Q160
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

479435:KFLA RS31345
gene id: 479435:KFLA_RS31345
uniprot id: D2PVS3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

479435:KFLA RS27485
gene id: 479435:KFLA_RS27485
uniprot id: D2PN66
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

479435:KFLA RS33150
gene id: 479435:KFLA_RS33150
uniprot id: D2PZU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

479435:KFLA RS08180
gene id: 479435:KFLA_RS08180
uniprot id: D2PMK8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

479435:KFLA RS22765
gene id: 479435:KFLA_RS22765
uniprot id: D2PY09
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

479435:KFLA RS20605
gene id: 479435:KFLA_RS20605
uniprot id: D2PSQ5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

479435:KFLA RS27475
gene id: 479435:KFLA_RS27475
uniprot id: D2PN64
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS05135
gene id: 479435:KFLA_RS05135
uniprot id: D2Q1G0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

479435:KFLA RS21090
gene id: 479435:KFLA_RS21090
uniprot id: D2PU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS19570
gene id: 479435:KFLA_RS19570
uniprot id: D2PR42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS27945
gene id: 479435:KFLA_RS27945
uniprot id: D2PP44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

479435:KFLA RS34550
gene id: 479435:KFLA_RS34550
uniprot id: D2Q3R9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

479435:KFLA RS04715
gene id: 479435:KFLA_RS04715
uniprot id: D2Q065
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS08490
gene id: 479435:KFLA_RS08490
uniprot id: D2PNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

479435:KFLA RS24140
gene id: 479435:KFLA_RS24140
uniprot id: D2Q0T5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

479435:KFLA RS04565
gene id: 479435:KFLA_RS04565
uniprot id: D2Q035
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

479435:KFLA RS30055
gene id: 479435:KFLA_RS30055
uniprot id: D2PT07
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS07890
gene id: 479435:KFLA_RS07890
uniprot id: D2PMF2
names: Similarity
messages: Belongs to the PGI/PMI family.

479435:KFLA RS11950
gene id: 479435:KFLA_RS11950
uniprot id: D2PV23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

479435:KFLA RS31160
gene id: 479435:KFLA_RS31160
uniprot id: D2PVN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS27515
gene id: 479435:KFLA_RS27515
uniprot id: D2PN72
names: Similarity
messages: Belongs to the AHA1 family.

479435:KFLA RS17830
gene id: 479435:KFLA_RS17830
uniprot id: D2PMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS35185
gene id: 479435:KFLA_RS35185
uniprot id: D2Q560
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

479435:KFLA RS33625
gene id: 479435:KFLA_RS33625
uniprot id: D2Q156
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

479435:KFLA RS07120
gene id: 479435:KFLA_RS07120
uniprot id: D2PKN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

479435:KFLA RS00370
gene id: 479435:KFLA_RS00370
uniprot id: D2PQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS13960
gene id: 479435:KFLA_RS13960
uniprot id: D2Q093
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS04480
gene id: 479435:KFLA_RS04480
uniprot id: D2Q016
names: Similarity
messages: Belongs to the XFP family.

479435:KFLA RS17030
gene id: 479435:KFLA_RS17030
uniprot id: D2PLQ5
names: Similarity
messages: Belongs to the universal stress protein A family.

479435:KFLA RS30455
gene id: 479435:KFLA_RS30455
uniprot id: D2PU88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

479435:KFLA RS19910
gene id: 479435:KFLA_RS19910
uniprot id: D2PRA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

479435:KFLA RS25615
gene id: 479435:KFLA_RS25615
uniprot id: D2Q4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

479435:KFLA RS16030
gene id: 479435:KFLA_RS16030
uniprot id: D2Q4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

479435:KFLA RS11345
gene id: 479435:KFLA_RS11345
uniprot id: D2PTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

479435:KFLA RS18760
gene id: 479435:KFLA_RS18760
uniprot id: D2PP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

479435:KFLA RS28020
gene id: 479435:KFLA_RS28020
uniprot id: D2PP59
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

479435:KFLA RS16410
gene id: 479435:KFLA_RS16410
uniprot id: D2PKQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

479435:KFLA RS00470
gene id: 479435:KFLA_RS00470
uniprot id: D2PQN5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

479435:KFLA RS09290
gene id: 479435:KFLA_RS09290
uniprot id: D2PPL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

479435:KFLA RS33285
gene id: 479435:KFLA_RS33285
uniprot id: D2Q0Z0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

479435:KFLA RS30955
gene id: 479435:KFLA_RS30955
uniprot id: D2PVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

479435:KFLA RS13760
gene id: 479435:KFLA_RS13760
uniprot id: D2PZ51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

479435:KFLA RS26325
gene id: 479435:KFLA_RS26325
uniprot id: D2PL69
names: Similarity
messages: Belongs to the peptidase S16 family.

479435:KFLA RS31380
gene id: 479435:KFLA_RS31380
uniprot id: D2PWU0
names: Subunit
messages: Homodimer.

479435:KFLA RS15830
gene id: 479435:KFLA_RS15830
uniprot id: D2Q4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

479435:KFLA RS19960
gene id: 479435:KFLA_RS19960
uniprot id: D2PRB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS29315
gene id: 479435:KFLA_RS29315
uniprot id: D2PRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS30450
gene id: 479435:KFLA_RS30450
uniprot id: D2PU87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

479435:KFLA RS33765
gene id: 479435:KFLA_RS33765
uniprot id: D2Q289
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

479435:KFLA RS19180
gene id: 479435:KFLA_RS19180
uniprot id: D2PPZ0
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS08640
gene id: 479435:KFLA_RS08640
uniprot id: D2PNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS18175
gene id: 479435:KFLA_RS18175
uniprot id: D2PN13
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

479435:KFLA RS21850
gene id: 479435:KFLA_RS21850
uniprot id: D2PVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

479435:KFLA RS21325
gene id: 479435:KFLA_RS21325
uniprot id: D2PV50
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

479435:KFLA RS30290
gene id: 479435:KFLA_RS30290
uniprot id: D2PU55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

479435:KFLA RS25980
gene id: 479435:KFLA_RS25980
uniprot id: D2Q4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS11370
gene id: 479435:KFLA_RS11370
uniprot id: D2PTR3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

479435:KFLA RS02180
gene id: 479435:KFLA_RS02180
uniprot id: D2PUP1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

479435:KFLA RS17140
gene id: 479435:KFLA_RS17140
uniprot id: D2PLS7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

479435:KFLA RS05030
gene id: 479435:KFLA_RS05030
uniprot id: D2Q1D9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

479435:KFLA RS17800
gene id: 479435:KFLA_RS17800
uniprot id: D2PMU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

479435:KFLA RS25335
gene id: 479435:KFLA_RS25335
uniprot id: D2Q3K3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

479435:KFLA RS19590
gene id: 479435:KFLA_RS19590
uniprot id: D2PR46
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

479435:KFLA RS08840
gene id: 479435:KFLA_RS08840
uniprot id: D2PNN3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

479435:KFLA RS10810
gene id: 479435:KFLA_RS10810
uniprot id: D2PTF9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

479435:KFLA RS07770
gene id: 479435:KFLA_RS07770
uniprot id: D2PLP4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

479435:KFLA RS24230
gene id: 479435:KFLA_RS24230
uniprot id: D2Q0V4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

479435:KFLA RS00060
gene id: 479435:KFLA_RS00060
uniprot id: D2PQF5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

479435:KFLA RS31570
gene id: 479435:KFLA_RS31570
uniprot id: D2PWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS16970
gene id: 479435:KFLA_RS16970
uniprot id: D2PL06
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

479435:KFLA RS18515
gene id: 479435:KFLA_RS18515
uniprot id: D2PNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

479435:KFLA RS26160
gene id: 479435:KFLA_RS26160
uniprot id: D2PL35
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

479435:KFLA RS06280
gene id: 479435:KFLA_RS06280
uniprot id: D2Q462
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

479435:KFLA RS20075
gene id: 479435:KFLA_RS20075
uniprot id: D2PSF1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

479435:KFLA RS13655
gene id: 479435:KFLA_RS13655
uniprot id: D2PZ30
names: Similarity
messages: Belongs to the cytidylyltransferase family.

479435:KFLA RS32970
gene id: 479435:KFLA_RS32970
uniprot id: D2PZR2
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS15965
gene id: 479435:KFLA_RS15965
uniprot id: D2Q4H0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

479435:KFLA RS07740
gene id: 479435:KFLA_RS07740
uniprot id: D2PLN8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

479435:KFLA RS23510
gene id: 479435:KFLA_RS23510
uniprot id: D2PZF3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

479435:KFLA RS19175
gene id: 479435:KFLA_RS19175
uniprot id: D2PPY9
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25310
gene id: 479435:KFLA_RS25310
uniprot id: D2Q3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS01875
gene id: 479435:KFLA_RS01875
uniprot id: D2PUI3
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS25035
gene id: 479435:KFLA_RS25035
uniprot id: D2Q3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

479435:KFLA RS26290
gene id: 479435:KFLA_RS26290
uniprot id: D2PL64
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

479435:KFLA RS11385
gene id: 479435:KFLA_RS11385
uniprot id: D2PTR6
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS06180
gene id: 479435:KFLA_RS06180
uniprot id: D2Q441
names: Similarity
messages: Belongs to the peptidase S14 family.

479435:KFLA RS28670
gene id: 479435:KFLA_RS28670
uniprot id: D2PQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

479435:KFLA RS24220
gene id: 479435:KFLA_RS24220
uniprot id: D2Q0V2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

479435:KFLA RS04665
gene id: 479435:KFLA_RS04665
uniprot id: D2Q055
names: Subcellular Location Annotation
messages: Membrane

479435:KFLA RS31600
gene id: 479435:KFLA_RS31600
uniprot id: D2PWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

479435:KFLA RS25755
gene id: 479435:KFLA_RS25755
uniprot id: D2Q4V5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.