47917:WN53 RS07850
gene id: 47917:WN53_RS07850
uniprot id: A0A0F7H971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS03735
gene id: 47917:WN53_RS03735
uniprot id: A0A0F7H8E1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

47917:WN53 RS20170
gene id: 47917:WN53_RS20170
uniprot id: A0A0F7HF65
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

47917:WN53 RS18240
gene id: 47917:WN53_RS18240
uniprot id: A0A0F7HEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS24825
gene id: 47917:WN53_RS24825
uniprot id: A0A0F7HH10
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

47917:WN53 RS26675
gene id: 47917:WN53_RS26675
uniprot id: A0A0F7HHP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS19575
gene id: 47917:WN53_RS19575
uniprot id: A0A0F7HDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

47917:WN53 RS23900
gene id: 47917:WN53_RS23900
uniprot id: A0A0F7HF56
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

47917:WN53 RS12720
gene id: 47917:WN53_RS12720
uniprot id: A0A0F7HHS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

47917:WN53 RS19140
gene id: 47917:WN53_RS19140
uniprot id: A0A0F7HDQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

47917:WN53 RS12105
gene id: 47917:WN53_RS12105
uniprot id: A0A0F7HAM3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

47917:WN53 RS07770
gene id: 47917:WN53_RS07770
uniprot id: A0A0F7HA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

47917:WN53 RS05880
gene id: 47917:WN53_RS05880
uniprot id: A0A0F7H932
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

47917:WN53 RS06375
gene id: 47917:WN53_RS06375
uniprot id: A0A0F7H9F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

47917:WN53 RS00645
gene id: 47917:WN53_RS00645
uniprot id: A0A0F7H6A1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14065
gene id: 47917:WN53_RS14065
uniprot id: A0A0F7HBH6
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

47917:WN53 RS09255
gene id: 47917:WN53_RS09255
uniprot id: A0A0F7HB11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

47917:WN53 RS19110
gene id: 47917:WN53_RS19110
uniprot id: A0A0F7D2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

47917:WN53 RS25250
gene id: 47917:WN53_RS25250
uniprot id: A0A0F7HH85
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

47917:WN53 RS13335
gene id: 47917:WN53_RS13335
uniprot id: A0A0F7D226
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23930
gene id: 47917:WN53_RS23930
uniprot id: A0A0F7HF60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

47917:WN53 RS21350
gene id: 47917:WN53_RS21350
uniprot id: A0A0F7D2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

47917:WN53 RS21335
gene id: 47917:WN53_RS21335
uniprot id: A0A0F7HG87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

47917:WN53 RS26295
gene id: 47917:WN53_RS26295
uniprot id: A0A0F7HHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS07870
gene id: 47917:WN53_RS07870
uniprot id: A0A0F7D1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS02910
gene id: 47917:WN53_RS02910
uniprot id: A0A0F7D110
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

47917:WN53 RS16100
gene id: 47917:WN53_RS16100
uniprot id: A0A0F7HD45
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

47917:WN53 RS18785
gene id: 47917:WN53_RS18785
uniprot id: A0A0F7HEG3
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

47917:WN53 RS05195
gene id: 47917:WN53_RS05195
uniprot id: A0A0F7H8Z0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

47917:WN53 RS16270
gene id: 47917:WN53_RS16270
uniprot id: A0A0F7HEA5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS17195
gene id: 47917:WN53_RS17195
uniprot id: A0A0F7HEK2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

47917:WN53 RS19530
gene id: 47917:WN53_RS19530
uniprot id: A0A4U9VEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS05550
gene id: 47917:WN53_RS05550
uniprot id: A0A0F7HHQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

47917:WN53 RS25325
gene id: 47917:WN53_RS25325
uniprot id: A0A0F7HH97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS01085
gene id: 47917:WN53_RS01085
uniprot id: A0A0F7H659
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

47917:WN53 RS11730
gene id: 47917:WN53_RS11730
uniprot id: A0A0F7HBQ3
names: Similarity
messages: Belongs to the UPF0246 family.

47917:WN53 RS24560
gene id: 47917:WN53_RS24560
uniprot id: A0A0F7D384
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

47917:WN53 RS19290
gene id: 47917:WN53_RS19290
uniprot id: A0A0F7HFK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

47917:WN53 RS22245
gene id: 47917:WN53_RS22245
uniprot id: A0A0F7HGR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS06755
gene id: 47917:WN53_RS06755
uniprot id: A0A0F7H9J8
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

47917:WN53 RS11805
gene id: 47917:WN53_RS11805
uniprot id: A0A0F7HC45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

47917:WN53 RS15890
gene id: 47917:WN53_RS15890
uniprot id: A0A0F7HC96
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

47917:WN53 RS22085
gene id: 47917:WN53_RS22085
uniprot id: A0A0F7HEM4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

47917:WN53 RS19925
gene id: 47917:WN53_RS19925
uniprot id: A0A0F7HF35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

47917:WN53 RS03775
gene id: 47917:WN53_RS03775
uniprot id: A0A0F7H881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

47917:WN53 RS25225
gene id: 47917:WN53_RS25225
uniprot id: A0A0F7HI01
names: Similarity
messages: Belongs to the GSP N family.

47917:WN53 RS22320
gene id: 47917:WN53_RS22320
uniprot id: A0A0F7D305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

47917:WN53 RS21195
gene id: 47917:WN53_RS21195
uniprot id: A0A0F7D2W4
names: Similarity
messages: Belongs to the FGGY kinase family.

47917:WN53 RS16275
gene id: 47917:WN53_RS16275
uniprot id: A0A0F7HCE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

47917:WN53 RS06785
gene id: 47917:WN53_RS06785
uniprot id: A0A0F7H9L5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS18485
gene id: 47917:WN53_RS18485
uniprot id: A0A0F7HE54
names: Similarity
messages: Belongs to the HupF/HypC family.

47917:WN53 RS14625
gene id: 47917:WN53_RS14625
uniprot id: A0A0F7D3J5
names: Subunit
messages: Homodimer.

47917:WN53 RS08265
gene id: 47917:WN53_RS08265
uniprot id: A0A0F7HGH9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09150
gene id: 47917:WN53_RS09150
uniprot id: A0A0F7HAB4
names: Function
messages: Required for maximal bacterial cellulose synthesis.

47917:WN53 RS16560
gene id: 47917:WN53_RS16560
uniprot id: A0A0F7HEE4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS12355
gene id: 47917:WN53_RS12355
uniprot id: A0A0F7HBX1
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

47917:WN53 RS00990
gene id: 47917:WN53_RS00990
uniprot id: A0A0F7H644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS17760
gene id: 47917:WN53_RS17760
uniprot id: A0A0F7HE20
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24760
gene id: 47917:WN53_RS24760
uniprot id: A0A0F7HGY4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06505
gene id: 47917:WN53_RS06505
uniprot id: A0A0F7D1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

47917:WN53 RS15180
gene id: 47917:WN53_RS15180
uniprot id: A0A0F7HCX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
messages: Interacts with MhpF.

47917:WN53 RS23885
gene id: 47917:WN53_RS23885
uniprot id: A0A0F7HGJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

47917:WN53 RS14345
gene id: 47917:WN53_RS14345
uniprot id: A0A0F7HCJ5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

47917:WN53 RS05445
gene id: 47917:WN53_RS05445
uniprot id: A0A0F7D199
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS08020
gene id: 47917:WN53_RS08020
uniprot id: A0A0F7HAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class A bacterial acid phosphatase family.
messages: Periplasm

47917:WN53 RS24125
gene id: 47917:WN53_RS24125
uniprot id: A0A0F7HGQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS10515
gene id: 47917:WN53_RS10515
uniprot id: A0A0F7HH56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

47917:WN53 RS14080
gene id: 47917:WN53_RS14080
uniprot id: A0A0F7HH88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

47917:WN53 RS19545
gene id: 47917:WN53_RS19545
uniprot id: A0A0F7D2Q4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

47917:WN53 RS09625
gene id: 47917:WN53_RS09625
uniprot id: A0A0F7HAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

47917:WN53 RS15800
gene id: 47917:WN53_RS15800
uniprot id: A0A0F7HC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

47917:WN53 RS22670
gene id: 47917:WN53_RS22670
uniprot id: A0A0F7HES2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

47917:WN53 RS23750
gene id: 47917:WN53_RS23750
uniprot id: A0A0F7HGI2
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

47917:WN53 RS23710
gene id: 47917:WN53_RS23710
uniprot id: A0A0F7HGI0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

47917:WN53 RS08330
gene id: 47917:WN53_RS08330
uniprot id: A0A0F7H9D7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05865
gene id: 47917:WN53_RS05865
uniprot id: A0A0F7D1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

47917:WN53 RS02435
gene id: 47917:WN53_RS02435
uniprot id: A0A0F7H6Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

47917:WN53 RS25585
gene id: 47917:WN53_RS25585
uniprot id: A0A0F7HI39
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06780
gene id: 47917:WN53_RS06780
uniprot id: A0A0F7D1E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

47917:WN53 RS04255
gene id: 47917:WN53_RS04255
uniprot id: A0A0F7H8N2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07460
gene id: 47917:WN53_RS07460
uniprot id: A0A0F7H9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

47917:WN53 RS13865
gene id: 47917:WN53_RS13865
uniprot id: A0A0F7D245
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Amino-acid racemase able to utilize a broad range of substrates.
messages: Belongs to the alanine racemase family. Bsr subfamily.
messages: Periplasm

47917:WN53 RS06825
gene id: 47917:WN53_RS06825
uniprot id: A0A0F7H9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS23420
gene id: 47917:WN53_RS23420
uniprot id: A0A0F7HFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS24520
gene id: 47917:WN53_RS24520
uniprot id: A0A0F7HFC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

47917:WN53 RS16480
gene id: 47917:WN53_RS16480
uniprot id: A0A0F7HDG8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS11985
gene id: 47917:WN53_RS11985
uniprot id: A0A0F7HBR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS07120
gene id: 47917:WN53_RS07120
uniprot id: A0A0F7D1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

47917:WN53 RS11630
gene id: 47917:WN53_RS11630
uniprot id: A0A0F7HAF5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

47917:WN53 RS16015
gene id: 47917:WN53_RS16015
uniprot id: A0A0F7HCB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

47917:WN53 RS16910
gene id: 47917:WN53_RS16910
uniprot id: A0A0F7HCQ4
names: Similarity
messages: Belongs to the alkaline phosphatase family.

47917:WN53 RS12615
gene id: 47917:WN53_RS12615
uniprot id: A0A0F7D203
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS25855
gene id: 47917:WN53_RS25855
uniprot id: A0A0F7HHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS01810
gene id: 47917:WN53_RS01810
uniprot id: A0A0F7H7H7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06830
gene id: 47917:WN53_RS06830
uniprot id: A0A0F7D1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS07610
gene id: 47917:WN53_RS07610
uniprot id: A0A0F7HA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS07735
gene id: 47917:WN53_RS07735
uniprot id: A0A3S5F3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

47917:WN53 RS15670
gene id: 47917:WN53_RS15670
uniprot id: A0A0F7HD58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

47917:WN53 RS22935
gene id: 47917:WN53_RS22935
uniprot id: A0A0F7HF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

47917:WN53 RS07005
gene id: 47917:WN53_RS07005
uniprot id: A0A0F7H9P7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

47917:WN53 RS26485
gene id: 47917:WN53_RS26485
uniprot id: A0A0F7D3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

47917:WN53 RS25665
gene id: 47917:WN53_RS25665
uniprot id: A0A0F7HGF1
names: Similarity
messages: Belongs to the UPF0304 family.

47917:WN53 RS15210
gene id: 47917:WN53_RS15210
uniprot id: A0A0F7HCX4
names: Similarity
messages: Belongs to the creatininase superfamily.

47917:WN53 RS09710
gene id: 47917:WN53_RS09710
uniprot id: A0A0F7H9U9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

47917:WN53 RS07100
gene id: 47917:WN53_RS07100
uniprot id: A0A0F7H8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

47917:WN53 RS10690
gene id: 47917:WN53_RS10690
uniprot id: A0A0F7D1T3
names: Similarity
messages: Belongs to the UPF0213 family.

47917:WN53 RS13730
gene id: 47917:WN53_RS13730
uniprot id: A0A0F7HCD9
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

47917:WN53 RS07030
gene id: 47917:WN53_RS07030
uniprot id: A0A0F7H8I1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

47917:WN53 RS16390
gene id: 47917:WN53_RS16390
uniprot id: A0A0F7HDF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

47917:WN53 RS02475
gene id: 47917:WN53_RS02475
uniprot id: A0A0F7D0Z4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

47917:WN53 RS01090
gene id: 47917:WN53_RS01090
uniprot id: A0A0F7H7C8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

47917:WN53 RS09160
gene id: 47917:WN53_RS09160
uniprot id: A0A0F7H9M2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06300
gene id: 47917:WN53_RS06300
uniprot id: A0A0F7H9E6
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

47917:WN53 RS25010
gene id: 47917:WN53_RS25010
uniprot id: A0A0F7D3A0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS04305
gene id: 47917:WN53_RS04305
uniprot id: A0A0F7D156
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

47917:WN53 RS07725
gene id: 47917:WN53_RS07725
uniprot id: A0A0F7H8X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

47917:WN53 RS27130
gene id: 47917:WN53_RS27130
uniprot id: A0A1Q5VBT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

47917:WN53 RS14110
gene id: 47917:WN53_RS14110
uniprot id: A0A0F7HBD8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

47917:WN53 RS02705
gene id: 47917:WN53_RS02705
uniprot id: A0A0F7H7S3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

47917:WN53 RS00775
gene id: 47917:WN53_RS00775
uniprot id: A0A0F7H6C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

47917:WN53 RS09485
gene id: 47917:WN53_RS09485
uniprot id: A0A0F7H9R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

47917:WN53 RS24720
gene id: 47917:WN53_RS24720
uniprot id: A0A0F7HGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS14360
gene id: 47917:WN53_RS14360
uniprot id: A0A0F7HBJ9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS11895
gene id: 47917:WN53_RS11895
uniprot id: A0A0F7D1X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

47917:WN53 RS25060
gene id: 47917:WN53_RS25060
uniprot id: A0A0F7HG65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

47917:WN53 RS23865
gene id: 47917:WN53_RS23865
uniprot id: A0A0F7HF52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

47917:WN53 RS02390
gene id: 47917:WN53_RS02390
uniprot id: A0A0F7H859
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

47917:WN53 RS04700
gene id: 47917:WN53_RS04700
uniprot id: A0A0F7H938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

47917:WN53 RS05425
gene id: 47917:WN53_RS05425
uniprot id: A0A0F7H919
names: Similarity
messages: Belongs to the Fur family.

47917:WN53 RS10820
gene id: 47917:WN53_RS10820
uniprot id: A0A0F7D1T8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

47917:WN53 RS26060
gene id: 47917:WN53_RS26060
uniprot id: A0A0F7HI95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

47917:WN53 RS24115
gene id: 47917:WN53_RS24115
uniprot id: A0A0F7D368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

47917:WN53 RS15005
gene id: 47917:WN53_RS15005
uniprot id: A0A0F7HBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS16650
gene id: 47917:WN53_RS16650
uniprot id: A0A0F7HDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

47917:WN53 RS25025
gene id: 47917:WN53_RS25025
uniprot id: A0A0F7HID2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

47917:WN53 RS23215
gene id: 47917:WN53_RS23215
uniprot id: A0A0F7HG85
names: Similarity
messages: Belongs to the transposase 7 family.

47917:WN53 RS17545
gene id: 47917:WN53_RS17545
uniprot id: A0A0F7HDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS07605
gene id: 47917:WN53_RS07605
uniprot id: A0A0F7D1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

47917:WN53 RS06765
gene id: 47917:WN53_RS06765
uniprot id: A0A0F7H8P1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS24380
gene id: 47917:WN53_RS24380
uniprot id: A0A0F7HFQ7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22550
gene id: 47917:WN53_RS22550
uniprot id: A0A0F7HG30
names: Similarity
messages: Belongs to the RutC family.

47917:WN53 RS12065
gene id: 47917:WN53_RS12065
uniprot id: A0A0F7HAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

47917:WN53 RS05910
gene id: 47917:WN53_RS05910
uniprot id: A0A0F7H935
names: Similarity
messages: Belongs to the SlyX family.

47917:WN53 RS05325
gene id: 47917:WN53_RS05325
uniprot id: A0A0F7H7U2
names: Similarity
messages: Belongs to the GST superfamily.

47917:WN53 RS09265
gene id: 47917:WN53_RS09265
uniprot id: A0A0F7H9F8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26620
gene id: 47917:WN53_RS26620
uniprot id: A0A0F7HIE7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

47917:WN53 RS16775
gene id: 47917:WN53_RS16775
uniprot id: A0A0F7HCL7
names: Similarity
messages: Belongs to the hyi family.

47917:WN53 RS09895
gene id: 47917:WN53_RS09895
uniprot id: A0A0F7HAK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

47917:WN53 RS17065
gene id: 47917:WN53_RS17065
uniprot id: A0A0F7HDH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

47917:WN53 RS13565
gene id: 47917:WN53_RS13565
uniprot id: A0A0F7HB63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

47917:WN53 RS20265
gene id: 47917:WN53_RS20265
uniprot id: A0A0F7HE33
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

47917:WN53 RS12405
gene id: 47917:WN53_RS12405
uniprot id: A0A0F7D1Z6
names: Similarity
messages: Belongs to the GSP E family.

47917:WN53 RS23610
gene id: 47917:WN53_RS23610
uniprot id: A0A0F7D350
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS04320
gene id: 47917:WN53_RS04320
uniprot id: A0A0F7H7F5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25235
gene id: 47917:WN53_RS25235
uniprot id: A0A0F7HG92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

47917:WN53 RS25100
gene id: 47917:WN53_RS25100
uniprot id: A0A0F7HH42
names: Similarity
messages: Belongs to the peptidase C40 family.

47917:WN53 RS03980
gene id: 47917:WN53_RS03980
uniprot id: A0A0F7H770
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

47917:WN53 RS09375
gene id: 47917:WN53_RS09375
uniprot id: A0A0F7HB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

47917:WN53 RS26670
gene id: 47917:WN53_RS26670
uniprot id: A0A0F7D3F8
names: Similarity
messages: Belongs to the UPF0178 family.

47917:WN53 RS19235
gene id: 47917:WN53_RS19235
uniprot id: A0A0F7D2P3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

47917:WN53 RS16215
gene id: 47917:WN53_RS16215
uniprot id: A0A0F7HCE0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS10250
gene id: 47917:WN53_RS10250
uniprot id: A0A0F7HB49
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20675
gene id: 47917:WN53_RS20675
uniprot id: A0A0F7HF76
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

47917:WN53 RS26010
gene id: 47917:WN53_RS26010
uniprot id: A0A0F7HGH8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS03720
gene id: 47917:WN53_RS03720
uniprot id: A0A4U9VYL7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00215
gene id: 47917:WN53_RS00215
uniprot id: A0A0F7H797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

47917:WN53 RS25020
gene id: 47917:WN53_RS25020
uniprot id: A0A0F7HG24
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

47917:WN53 RS04640
gene id: 47917:WN53_RS04640
uniprot id: A0A0F7H7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

47917:WN53 RS26430
gene id: 47917:WN53_RS26430
uniprot id: A0A0F7HHL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS04575
gene id: 47917:WN53_RS04575
uniprot id: A0A4U9W8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

47917:WN53 RS25640
gene id: 47917:WN53_RS25640
uniprot id: A0A0F7HH93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS15370
gene id: 47917:WN53_RS15370
uniprot id: A0A0F7HBW5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

47917:WN53 RS25595
gene id: 47917:WN53_RS25595
uniprot id: A0A0F7HFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS13835
gene id: 47917:WN53_RS13835
uniprot id: A0A0F7HB81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS14280
gene id: 47917:WN53_RS14280
uniprot id: A0A0F7HCI9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS19620
gene id: 47917:WN53_RS19620
uniprot id: A0A0F7HEZ8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05840
gene id: 47917:WN53_RS05840
uniprot id: A0A0F7D1B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS08210
gene id: 47917:WN53_RS08210
uniprot id: A0A0F7H934
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

47917:WN53 RS10605
gene id: 47917:WN53_RS10605
uniprot id: A0A0F7HAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

47917:WN53 RS17110
gene id: 47917:WN53_RS17110
uniprot id: A0A0F7HCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

47917:WN53 RS22145
gene id: 47917:WN53_RS22145
uniprot id: A0A0F7HIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS10145
gene id: 47917:WN53_RS10145
uniprot id: A0A0F7H9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

47917:WN53 RS12130
gene id: 47917:WN53_RS12130
uniprot id: A0A0F7HAT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

47917:WN53 RS17200
gene id: 47917:WN53_RS17200
uniprot id: A0A0F7HCS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS23690
gene id: 47917:WN53_RS23690
uniprot id: A0A0F7HFI7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS02060
gene id: 47917:WN53_RS02060
uniprot id: A0A0F7H6U3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22190
gene id: 47917:WN53_RS22190
uniprot id: A0A0F7HEN2
names: Similarity
messages: Belongs to the Dps family.

47917:WN53 RS06805
gene id: 47917:WN53_RS06805
uniprot id: A0A0F7D1E9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS27695
gene id: 47917:WN53_RS27695
uniprot id: A0A0F7HEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS11625
gene id: 47917:WN53_RS11625
uniprot id: A0A0F7HAL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

47917:WN53 RS01585
gene id: 47917:WN53_RS01585
uniprot id: A0A0F7H7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

47917:WN53 RS08780
gene id: 47917:WN53_RS08780
uniprot id: A0A0F7H9A8
names: Similarity
messages: Belongs to the asparaginase 1 family.

47917:WN53 RS02860
gene id: 47917:WN53_RS02860
uniprot id: A0A0F7D108
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

47917:WN53 RS18660
gene id: 47917:WN53_RS18660
uniprot id: A0A0F7HF66
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

47917:WN53 RS02330
gene id: 47917:WN53_RS02330
uniprot id: A0A0F7D0Y9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

47917:WN53 RS13735
gene id: 47917:WN53_RS13735
uniprot id: A0A0F7D3J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

47917:WN53 RS13360
gene id: 47917:WN53_RS13360
uniprot id: A0A0F7D227
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

47917:WN53 RS09910
gene id: 47917:WN53_RS09910
uniprot id: A0A0F7H9X2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23390
gene id: 47917:WN53_RS23390
uniprot id: A0A0F7HFB9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

47917:WN53 RS16700
gene id: 47917:WN53_RS16700
uniprot id: A0A0F7D2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

47917:WN53 RS18135
gene id: 47917:WN53_RS18135
uniprot id: A0A0F7HDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS07335
gene id: 47917:WN53_RS07335
uniprot id: A0A0F7HA68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

47917:WN53 RS15820
gene id: 47917:WN53_RS15820
uniprot id: A0A0F7HE51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

47917:WN53 RS21525
gene id: 47917:WN53_RS21525
uniprot id: A0A0F7HEL1
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

47917:WN53 RS05905
gene id: 47917:WN53_RS05905
uniprot id: A0A0F7H991
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

47917:WN53 RS09550
gene id: 47917:WN53_RS09550
uniprot id: A0A0F7H9J7
names: Similarity
messages: Belongs to the leucine-binding protein family.

47917:WN53 RS05680
gene id: 47917:WN53_RS05680
uniprot id: A0A0F7H951
names: Similarity
messages: Belongs to the DprA/Smf family.

47917:WN53 RS00535
gene id: 47917:WN53_RS00535
uniprot id: A0A0F7H647
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

47917:WN53 RS11785
gene id: 47917:WN53_RS11785
uniprot id: A0A0F7HAH9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

47917:WN53 RS06090
gene id: 47917:WN53_RS06090
uniprot id: A0A0F7D1C3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

47917:WN53 RS20150
gene id: 47917:WN53_RS20150
uniprot id: A0A0F7D2S6
names: Similarity
messages: Belongs to the CFA/CMAS family.

47917:WN53 RS21190
gene id: 47917:WN53_RS21190
uniprot id: Q9RIR4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS13170
gene id: 47917:WN53_RS13170
uniprot id: A0A0F7HC72
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23475
gene id: 47917:WN53_RS23475
uniprot id: A0A0F7D345
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

47917:WN53 RS23800
gene id: 47917:WN53_RS23800
uniprot id: A0A0F7HFJ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

47917:WN53 RS20245
gene id: 47917:WN53_RS20245
uniprot id: A0A0F7HFW5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS09900
gene id: 47917:WN53_RS09900
uniprot id: A0A0F7HB84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

47917:WN53 RS21310
gene id: 47917:WN53_RS21310
uniprot id: A0A0F7HE97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

47917:WN53 RS20450
gene id: 47917:WN53_RS20450
uniprot id: A0A0F7HF13
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23040
gene id: 47917:WN53_RS23040
uniprot id: A0A0F7D330
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

47917:WN53 RS22195
gene id: 47917:WN53_RS22195
uniprot id: A0A0F7HEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

47917:WN53 RS17240
gene id: 47917:WN53_RS17240
uniprot id: A0A0F7HCV6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

47917:WN53 RS17885
gene id: 47917:WN53_RS17885
uniprot id: A0A0F7HD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

47917:WN53 RS01725
gene id: 47917:WN53_RS01725
uniprot id: A0A0F7H6Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

47917:WN53 RS20400
gene id: 47917:WN53_RS20400
uniprot id: A0A0F7HE50
names: Similarity
messages: Belongs to the ribulokinase family.

47917:WN53 RS19105
gene id: 47917:WN53_RS19105
uniprot id: A0A0F7HDQ4
names: Similarity
messages: Belongs to the YciI family.

47917:WN53 RS17465
gene id: 47917:WN53_RS17465
uniprot id: A0A0F7HCX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

47917:WN53 RS09140
gene id: 47917:WN53_RS09140
uniprot id: A0A0F7HAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

47917:WN53 RS16195
gene id: 47917:WN53_RS16195
uniprot id: A0A0F7HDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

47917:WN53 RS14400
gene id: 47917:WN53_RS14400
uniprot id: A0A0F7HBM1
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
messages: Homodimer.

47917:WN53 RS20135
gene id: 47917:WN53_RS20135
uniprot id: A0A0F7HE22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

47917:WN53 RS07075
gene id: 47917:WN53_RS07075
uniprot id: A0A0F7H9P4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07360
gene id: 47917:WN53_RS07360
uniprot id: A0A0F7H9T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

47917:WN53 RS15785
gene id: 47917:WN53_RS15785
uniprot id: A0A0F7D2B6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

47917:WN53 RS13715
gene id: 47917:WN53_RS13715
uniprot id: A0A0F7D240
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

47917:WN53 RS24865
gene id: 47917:WN53_RS24865
uniprot id: A0A0F7HH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS24725
gene id: 47917:WN53_RS24725
uniprot id: A0A0F7HGY0
names: Similarity
messages: Belongs to the leucine-binding protein family.

47917:WN53 RS19405
gene id: 47917:WN53_RS19405
uniprot id: A0A0F7HEW8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

47917:WN53 RS12165
gene id: 47917:WN53_RS12165
uniprot id: A0A0F7HAN2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS16785
gene id: 47917:WN53_RS16785
uniprot id: A0A0F7HCE7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

47917:WN53 RS00035
gene id: 47917:WN53_RS00035
uniprot id: A0A0F7H6Q1
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

47917:WN53 RS23945
gene id: 47917:WN53_RS23945
uniprot id: A0A0F7HGH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

47917:WN53 RS19500
gene id: 47917:WN53_RS19500
uniprot id: A0A0F7HHG2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

47917:WN53 RS16070
gene id: 47917:WN53_RS16070
uniprot id: A0A0F7D2C6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23395
gene id: 47917:WN53_RS23395
uniprot id: A0A0F7HGB8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS11855
gene id: 47917:WN53_RS11855
uniprot id: A0A0F7HAI9
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

47917:WN53 RS12775
gene id: 47917:WN53_RS12775
uniprot id: A0A0F7HC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS05705
gene id: 47917:WN53_RS05705
uniprot id: A0A0F7H7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

47917:WN53 RS11110
gene id: 47917:WN53_RS11110
uniprot id: A0A0F7HB35
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-1114 that is involved in catalysis.

47917:WN53 RS09580
gene id: 47917:WN53_RS09580
uniprot id: A0A0F7D1P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).
messages: sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE.

47917:WN53 RS02560
gene id: 47917:WN53_RS02560
uniprot id: A0A0F7H7X9
names: Similarity
messages: Belongs to the TPP enzyme family.

47917:WN53 RS21995
gene id: 47917:WN53_RS21995
uniprot id: A0A0F7D2Z3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

47917:WN53 RS21145
gene id: 47917:WN53_RS21145
uniprot id: A0A0F7HFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

47917:WN53 RS15070
gene id: 47917:WN53_RS15070
uniprot id: A0A0F7HBZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS24375
gene id: 47917:WN53_RS24375
uniprot id: A0A0F7HFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

47917:WN53 RS24530
gene id: 47917:WN53_RS24530
uniprot id: A0A0F7D383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

47917:WN53 RS14405
gene id: 47917:WN53_RS14405
uniprot id: A0A0F7HCK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS10380
gene id: 47917:WN53_RS10380
uniprot id: A0A0F7HA17
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

47917:WN53 RS21510
gene id: 47917:WN53_RS21510
uniprot id: A0A0F7HGE8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

47917:WN53 RS18420
gene id: 47917:WN53_RS18420
uniprot id: A0A0F7HE47
names: Similarity
messages: Belongs to the peptidase A31 family.

47917:WN53 RS24155
gene id: 47917:WN53_RS24155
uniprot id: A0A0F7HGR5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20290
gene id: 47917:WN53_RS20290
uniprot id: A0A0F7HDV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

47917:WN53 RS17820
gene id: 47917:WN53_RS17820
uniprot id: A0A0F7HD35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

47917:WN53 RS19895
gene id: 47917:WN53_RS19895
uniprot id: A0A0F7D2R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS04205
gene id: 47917:WN53_RS04205
uniprot id: A0A0F7H8W7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

47917:WN53 RS13195
gene id: 47917:WN53_RS13195
uniprot id: A0A0F7HB88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

47917:WN53 RS17555
gene id: 47917:WN53_RS17555
uniprot id: A0A0F7HCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

47917:WN53 RS09905
gene id: 47917:WN53_RS09905
uniprot id: A0A0F7D1Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

47917:WN53 RS06730
gene id: 47917:WN53_RS06730
uniprot id: A0A0F7H9X5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06290
gene id: 47917:WN53_RS06290
uniprot id: A0A0F7H8I3
names: Similarity
messages: Belongs to the FeoA family.

47917:WN53 RS04330
gene id: 47917:WN53_RS04330
uniprot id: A0A0F7D157
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

47917:WN53 RS05495
gene id: 47917:WN53_RS05495
uniprot id: A0A0F7D1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS22690
gene id: 47917:WN53_RS22690
uniprot id: A0A0F7HG57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS13500
gene id: 47917:WN53_RS13500
uniprot id: A0A0F7HB44
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

47917:WN53 RS08005
gene id: 47917:WN53_RS08005
uniprot id: A0A0F7HAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

47917:WN53 RS15165
gene id: 47917:WN53_RS15165
uniprot id: A0A0F7HC12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MhpC family.
messages: Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
messages: Homodimer.

47917:WN53 RS22220
gene id: 47917:WN53_RS22220
uniprot id: A0A0F7HEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS25265
gene id: 47917:WN53_RS25265
uniprot id: A0A0F7HFP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

47917:WN53 RS22330
gene id: 47917:WN53_RS22330
uniprot id: A0A0F7HF12
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

47917:WN53 RS14545
gene id: 47917:WN53_RS14545
uniprot id: A0A0F7D271
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

47917:WN53 RS07455
gene id: 47917:WN53_RS07455
uniprot id: A0A0F7H9X4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

47917:WN53 RS05685
gene id: 47917:WN53_RS05685
uniprot id: A0A0F7D1A7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

47917:WN53 RS17375
gene id: 47917:WN53_RS17375
uniprot id: A0A0F7HDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS22350
gene id: 47917:WN53_RS22350
uniprot id: A0A0F7HGS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

47917:WN53 RS01830
gene id: 47917:WN53_RS01830
uniprot id: A0A0F7D0X3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

47917:WN53 RS06590
gene id: 47917:WN53_RS06590
uniprot id: A0A0F7H9V7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

47917:WN53 RS06595
gene id: 47917:WN53_RS06595
uniprot id: A0A0F7H8M1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09195
gene id: 47917:WN53_RS09195
uniprot id: A0A0F7H9M5
names: Similarity
messages: Belongs to the thioredoxin family.

47917:WN53 RS07070
gene id: 47917:WN53_RS07070
uniprot id: A0A0F7H9Q8
names: Similarity
messages: Belongs to the FBPase class 2 family.

47917:WN53 RS06685
gene id: 47917:WN53_RS06685
uniprot id: A0A0F7H9J9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02795
gene id: 47917:WN53_RS02795
uniprot id: A0A0F7H6V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

47917:WN53 RS11915
gene id: 47917:WN53_RS11915
uniprot id: A0A0F7HAJ9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

47917:WN53 RS06310
gene id: 47917:WN53_RS06310
uniprot id: A0A0F7H994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

47917:WN53 RS12690
gene id: 47917:WN53_RS12690
uniprot id: A0A0F7D206
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

47917:WN53 RS11550
gene id: 47917:WN53_RS11550
uniprot id: A0A0F7HC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

47917:WN53 RS01645
gene id: 47917:WN53_RS01645
uniprot id: A0A0F7H7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

47917:WN53 RS15205
gene id: 47917:WN53_RS15205
uniprot id: A0A0F7HBU8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

47917:WN53 RS20140
gene id: 47917:WN53_RS20140
uniprot id: A0A0F7HF61
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

47917:WN53 RS14240
gene id: 47917:WN53_RS14240
uniprot id: A0A0F7D259
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

47917:WN53 RS02410
gene id: 47917:WN53_RS02410
uniprot id: A0A0F7H7V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

47917:WN53 RS15010
gene id: 47917:WN53_RS15010
uniprot id: A0A0F7D288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS01740
gene id: 47917:WN53_RS01740
uniprot id: A0A0F7H7M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

47917:WN53 RS11320
gene id: 47917:WN53_RS11320
uniprot id: A0A0F7HBM2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

47917:WN53 RS15975
gene id: 47917:WN53_RS15975
uniprot id: A0A0F7HD13
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

47917:WN53 RS05735
gene id: 47917:WN53_RS05735
uniprot id: A0A0F7H8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

47917:WN53 RS05210
gene id: 47917:WN53_RS05210
uniprot id: A0A0F7D190
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS23970
gene id: 47917:WN53_RS23970
uniprot id: A0A0F7HFK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

47917:WN53 RS01190
gene id: 47917:WN53_RS01190
uniprot id: A0A0F7H7E0
names: Similarity
messages: Belongs to the Rht family.

47917:WN53 RS00170
gene id: 47917:WN53_RS00170
uniprot id: A0A0F7D0R2
names: Similarity
messages: Belongs to the ArsC family.

47917:WN53 RS01435
gene id: 47917:WN53_RS01435
uniprot id: A0A0F7H7D2
names: Similarity
messages: Belongs to the aldose epimerase family.

47917:WN53 RS14130
gene id: 47917:WN53_RS14130
uniprot id: A0A0F7D255
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

47917:WN53 RS27645
gene id: 47917:WN53_RS27645
uniprot id: A0A292AK02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

47917:WN53 RS13450
gene id: 47917:WN53_RS13450
uniprot id: A0A0F7HD05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS19130
gene id: 47917:WN53_RS19130
uniprot id: A0A0F7HDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

47917:WN53 RS04515
gene id: 47917:WN53_RS04515
uniprot id: A0A0F7D164
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

47917:WN53 RS10090
gene id: 47917:WN53_RS10090
uniprot id: A0A0F7D1R1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

47917:WN53 RS11735
gene id: 47917:WN53_RS11735
uniprot id: A0A0F7HBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS24920
gene id: 47917:WN53_RS24920
uniprot id: A0A0F7HG08
names: Similarity
messages: Belongs to the UPF0265 family.

47917:WN53 RS24765
gene id: 47917:WN53_RS24765
uniprot id: A0A0F7D391
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

47917:WN53 RS18695
gene id: 47917:WN53_RS18695
uniprot id: A0A0F7D3K2
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

47917:WN53 RS19740
gene id: 47917:WN53_RS19740
uniprot id: A0A0F7D3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

47917:WN53 RS00720
gene id: 47917:WN53_RS00720
uniprot id: A0A0F7H603
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

47917:WN53 RS02405
gene id: 47917:WN53_RS02405
uniprot id: A0A0F7D3G4
names: Similarity
messages: Belongs to the UPF0149 family.

47917:WN53 RS25750
gene id: 47917:WN53_RS25750
uniprot id: A0A0F7HHD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS10230
gene id: 47917:WN53_RS10230
uniprot id: A0A0F7D1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

47917:WN53 RS25005
gene id: 47917:WN53_RS25005
uniprot id: A0A0F7HHQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

47917:WN53 RS20190
gene id: 47917:WN53_RS20190
uniprot id: A0A0F7HDT7
names: Similarity
messages: Belongs to the glyoxalase I family.

47917:WN53 RS22995
gene id: 47917:WN53_RS22995
uniprot id: A0A0F7D329
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

47917:WN53 RS10225
gene id: 47917:WN53_RS10225
uniprot id: A0A0F7HAP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

47917:WN53 RS10670
gene id: 47917:WN53_RS10670
uniprot id: A0A0F7HAW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

47917:WN53 RS01465
gene id: 47917:WN53_RS01465
uniprot id: A0A0F7H7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS25210
gene id: 47917:WN53_RS25210
uniprot id: A0A0F7D3A7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06155
gene id: 47917:WN53_RS06155
uniprot id: A0A0F7H868
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

47917:WN53 RS20535
gene id: 47917:WN53_RS20535
uniprot id: A0A0F7D2U0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01515
gene id: 47917:WN53_RS01515
uniprot id: A0A0F7H6C3
names: Similarity
messages: Belongs to the thioredoxin family.

47917:WN53 RS01440
gene id: 47917:WN53_RS01440
uniprot id: A0A0F7H7S8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

47917:WN53 RS19635
gene id: 47917:WN53_RS19635
uniprot id: A0A0F7HFP3
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

47917:WN53 RS17800
gene id: 47917:WN53_RS17800
uniprot id: A0A0F7HDP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS16035
gene id: 47917:WN53_RS16035
uniprot id: A0A0F7HD39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

47917:WN53 RS02300
gene id: 47917:WN53_RS02300
uniprot id: A0A0F7H6N1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

47917:WN53 RS09450
gene id: 47917:WN53_RS09450
uniprot id: A0A0F7H9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

47917:WN53 RS13365
gene id: 47917:WN53_RS13365
uniprot id: A0A0F7HC44
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

47917:WN53 RS24190
gene id: 47917:WN53_RS24190
uniprot id: A0A0F7D371
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24880
gene id: 47917:WN53_RS24880
uniprot id: A0A0F7HGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

47917:WN53 RS15105
gene id: 47917:WN53_RS15105
uniprot id: A0A0F7HC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS09305
gene id: 47917:WN53_RS09305
uniprot id: A0A0F7HB17
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

47917:WN53 RS20920
gene id: 47917:WN53_RS20920
uniprot id: A0A0F7HG47
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01070
gene id: 47917:WN53_RS01070
uniprot id: A0A0F7H7M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

47917:WN53 RS25860
gene id: 47917:WN53_RS25860
uniprot id: A0A0F7HHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

47917:WN53 RS07765
gene id: 47917:WN53_RS07765
uniprot id: A0A0F7HA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

47917:WN53 RS07155
gene id: 47917:WN53_RS07155
uniprot id: A0A0F7H8U0
names: Caution
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS17445
gene id: 47917:WN53_RS17445
uniprot id: A0A0F7HDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

47917:WN53 RS08240
gene id: 47917:WN53_RS08240
uniprot id: A0A0F7H940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

47917:WN53 RS08140
gene id: 47917:WN53_RS08140
uniprot id: A0A0F7H9B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

47917:WN53 RS13300
gene id: 47917:WN53_RS13300
uniprot id: A0A0F7HC34
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

47917:WN53 RS02085
gene id: 47917:WN53_RS02085
uniprot id: A0A0F7H822
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS04610
gene id: 47917:WN53_RS04610
uniprot id: A0A0F7H7W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS18760
gene id: 47917:WN53_RS18760
uniprot id: A0A0F7HE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS22895
gene id: 47917:WN53_RS22895
uniprot id: A0A0F7HF74
names: Similarity
messages: Belongs to the class-I fumarase family.

47917:WN53 RS19845
gene id: 47917:WN53_RS19845
uniprot id: A0A0F7HDY7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

47917:WN53 RS26225
gene id: 47917:WN53_RS26225
uniprot id: A0A0F7HHK7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22890
gene id: 47917:WN53_RS22890
uniprot id: A0A0F7HEU2
names: Similarity
messages: Belongs to the class-I fumarase family.

47917:WN53 RS02820
gene id: 47917:WN53_RS02820
uniprot id: A0A0F7H743
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

47917:WN53 RS22835
gene id: 47917:WN53_RS22835
uniprot id: A0A0F7HG67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS08010
gene id: 47917:WN53_RS08010
uniprot id: A0A0F7H992
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

47917:WN53 RS22605
gene id: 47917:WN53_RS22605
uniprot id: A0A0F7HG31
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS25755
gene id: 47917:WN53_RS25755
uniprot id: A0A0F7D3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS12125
gene id: 47917:WN53_RS12125
uniprot id: A0A0F7HCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

47917:WN53 RS24365
gene id: 47917:WN53_RS24365
uniprot id: A0A0F7HHE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

47917:WN53 RS11025
gene id: 47917:WN53_RS11025
uniprot id: A0A0F7HA79
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

47917:WN53 RS09735
gene id: 47917:WN53_RS09735
uniprot id: A0A0F7HB59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

47917:WN53 RS02845
gene id: 47917:WN53_RS02845
uniprot id: A0A0F7H8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS14060
gene id: 47917:WN53_RS14060
uniprot id: A0A0F7HD85
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

47917:WN53 RS07570
gene id: 47917:WN53_RS07570
uniprot id: A0A0F7D1H7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

47917:WN53 RS11475
gene id: 47917:WN53_RS11475
uniprot id: A0A0F7HAJ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS02265
gene id: 47917:WN53_RS02265
uniprot id: A0A0F7H7T6
names: Similarity
messages: Belongs to the RutC family.

47917:WN53 RS18085
gene id: 47917:WN53_RS18085
uniprot id: A0A0F7D2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

47917:WN53 RS06120
gene id: 47917:WN53_RS06120
uniprot id: A0A0F7D1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS12375
gene id: 47917:WN53_RS12375
uniprot id: A0A0F7HAW4
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

47917:WN53 RS07025
gene id: 47917:WN53_RS07025
uniprot id: A0A0F7H8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

47917:WN53 RS20080
gene id: 47917:WN53_RS20080
uniprot id: A0A0F7HFV2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

47917:WN53 RS19965
gene id: 47917:WN53_RS19965
uniprot id: A0A0F7HEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS07365
gene id: 47917:WN53_RS07365
uniprot id: A0A0F7HA70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

47917:WN53 RS07035
gene id: 47917:WN53_RS07035
uniprot id: A0A0F7H9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

47917:WN53 RS09440
gene id: 47917:WN53_RS09440
uniprot id: A0A0F7H9Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

47917:WN53 RS20695
gene id: 47917:WN53_RS20695
uniprot id: A0A0F7HE85
names: Similarity
messages: Belongs to the Nudix hydrolase family.

47917:WN53 RS12535
gene id: 47917:WN53_RS12535
uniprot id: A0A0F7HAY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS19865
gene id: 47917:WN53_RS19865
uniprot id: A0A0F7D2R6
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

47917:WN53 RS05825
gene id: 47917:WN53_RS05825
uniprot id: A0A0F7H9J6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

47917:WN53 RS19880
gene id: 47917:WN53_RS19880
uniprot id: A0A0F7HDZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS13505
gene id: 47917:WN53_RS13505
uniprot id: A0A0F7HCA9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

47917:WN53 RS19125
gene id: 47917:WN53_RS19125
uniprot id: A0A0F7HFG5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

47917:WN53 RS05460
gene id: 47917:WN53_RS05460
uniprot id: A0A0F7H8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

47917:WN53 RS01955
gene id: 47917:WN53_RS01955
uniprot id: A0A0F7H802
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

47917:WN53 RS17380
gene id: 47917:WN53_RS17380
uniprot id: A0A0F7HDK0
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

47917:WN53 RS17535
gene id: 47917:WN53_RS17535
uniprot id: A0A0F7HDY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

47917:WN53 RS17815
gene id: 47917:WN53_RS17815
uniprot id: A0A0F7HCY4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

47917:WN53 RS16760
gene id: 47917:WN53_RS16760
uniprot id: A0A0F7D2F2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS07590
gene id: 47917:WN53_RS07590
uniprot id: A0A0F7HAC5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

47917:WN53 RS14660
gene id: 47917:WN53_RS14660
uniprot id: A0A0F7HBQ0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14335
gene id: 47917:WN53_RS14335
uniprot id: A0A0F7HBI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

47917:WN53 RS23875
gene id: 47917:WN53_RS23875
uniprot id: A0A0F7HFJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

47917:WN53 RS09830
gene id: 47917:WN53_RS09830
uniprot id: A0A0F7H9N8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

47917:WN53 RS11285
gene id: 47917:WN53_RS11285
uniprot id: A0A0F7HBL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EcpA/MatB fimbrillin family.
messages: Fimbrium
messages: Self-associates. Forms filaments. Interacts with EcpD.

47917:WN53 RS17100
gene id: 47917:WN53_RS17100
uniprot id: A0A0F7HEJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

47917:WN53 RS04945
gene id: 47917:WN53_RS04945
uniprot id: A0A0F7D180
names: Similarity
messages: Belongs to the UPF0307 family.

47917:WN53 RS16395
gene id: 47917:WN53_RS16395
uniprot id: A0A0F7HD73
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS13645
gene id: 47917:WN53_RS13645
uniprot id: A0A0F7HD21
names: Similarity
messages: Belongs to the UPF0386 family.

47917:WN53 RS15445
gene id: 47917:WN53_RS15445
uniprot id: A0A0F7HCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

47917:WN53 RS25525
gene id: 47917:WN53_RS25525
uniprot id: A0A0F7HGD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS09330
gene id: 47917:WN53_RS09330
uniprot id: A0A0F7HIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS03110
gene id: 47917:WN53_RS03110
uniprot id: A0A0F7H8G4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS19730
gene id: 47917:WN53_RS19730
uniprot id: A0A0F7D2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

47917:WN53 RS00850
gene id: 47917:WN53_RS00850
uniprot id: A0A0F7H6D0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS06790
gene id: 47917:WN53_RS06790
uniprot id: A0A0F7H9K3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS16095
gene id: 47917:WN53_RS16095
uniprot id: A0A0F7D2C7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

47917:WN53 RS17355
gene id: 47917:WN53_RS17355
uniprot id: A0A0F7HEL6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

47917:WN53 RS00390
gene id: 47917:WN53_RS00390
uniprot id: A0A0F7H7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS15425
gene id: 47917:WN53_RS15425
uniprot id: A0A0F7HC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS03135
gene id: 47917:WN53_RS03135
uniprot id: A0A0F7H7Z3
names: Similarity
messages: Belongs to the peptidase A24 family.

47917:WN53 RS21885
gene id: 47917:WN53_RS21885
uniprot id: A0A0F7HEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS07480
gene id: 47917:WN53_RS07480
uniprot id: A0A0F7H8S4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

47917:WN53 RS19945
gene id: 47917:WN53_RS19945
uniprot id: A0A0F7D2R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

47917:WN53 RS12395
gene id: 47917:WN53_RS12395
uniprot id: A0A0F7HHS6
names: Similarity
messages: Belongs to the bacterial secretin family.

47917:WN53 RS11120
gene id: 47917:WN53_RS11120
uniprot id: A0A0F7HA92
names: Similarity
messages: Belongs to the CcmL/EutN family.

47917:WN53 RS09970
gene id: 47917:WN53_RS09970
uniprot id: A0A0F7HAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

47917:WN53 RS26115
gene id: 47917:WN53_RS26115
uniprot id: A0A0F7HHJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

47917:WN53 RS22825
gene id: 47917:WN53_RS22825
uniprot id: A0A0F7D323
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
messages: Cytoplasm

47917:WN53 RS00780
gene id: 47917:WN53_RS00780
uniprot id: A0A0F7D0T4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

47917:WN53 RS00360
gene id: 47917:WN53_RS00360
uniprot id: A0A0F7H616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

47917:WN53 RS17360
gene id: 47917:WN53_RS17360
uniprot id: A0A0F7D2H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

47917:WN53 RS18065
gene id: 47917:WN53_RS18065
uniprot id: A0A0F7HEV7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

47917:WN53 RS01635
gene id: 47917:WN53_RS01635
uniprot id: A0A0F7H6N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

47917:WN53 RS11230
gene id: 47917:WN53_RS11230
uniprot id: A0A0F7HGK7
names: Similarity
messages: Belongs to the autoinducer synthase family.

47917:WN53 RS00330
gene id: 47917:WN53_RS00330
uniprot id: A0A0F7H610
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

47917:WN53 RS19365
gene id: 47917:WN53_RS19365
uniprot id: A0A0F7HDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS25530
gene id: 47917:WN53_RS25530
uniprot id: A0A0F7D3B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

47917:WN53 RS17615
gene id: 47917:WN53_RS17615
uniprot id: A0A0F7D2I5
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

47917:WN53 RS22955
gene id: 47917:WN53_RS22955
uniprot id: A0A0F7HH01
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

47917:WN53 RS05565
gene id: 47917:WN53_RS05565
uniprot id: A0A0F7H8Z1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

47917:WN53 RS06920
gene id: 47917:WN53_RS06920
uniprot id: A0A0F7H9L9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

47917:WN53 RS05930
gene id: 47917:WN53_RS05930
uniprot id: A0A0F7H831
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

47917:WN53 RS07105
gene id: 47917:WN53_RS07105
uniprot id: A0A0F7H9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

47917:WN53 RS05895
gene id: 47917:WN53_RS05895
uniprot id: A0A0F7H8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

47917:WN53 RS00485
gene id: 47917:WN53_RS00485
uniprot id: A0A0F7H6X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

47917:WN53 RS24485
gene id: 47917:WN53_RS24485
uniprot id: A0A0F7HHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS10710
gene id: 47917:WN53_RS10710
uniprot id: A0A0F7HA57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS09995
gene id: 47917:WN53_RS09995
uniprot id: A0A0F7HB18
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

47917:WN53 RS14665
gene id: 47917:WN53_RS14665
uniprot id: A0A0F7HCN9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04310
gene id: 47917:WN53_RS04310
uniprot id: A0A0F7H8Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

47917:WN53 RS24805
gene id: 47917:WN53_RS24805
uniprot id: A0A0F7HFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
messages: Membrane

47917:WN53 RS25310
gene id: 47917:WN53_RS25310
uniprot id: A0A0F7HHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS14410
gene id: 47917:WN53_RS14410
uniprot id: A0A0F7HCJ0
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

47917:WN53 RS22810
gene id: 47917:WN53_RS22810
uniprot id: A0A0F7HET7
names: Similarity
messages: Belongs to the thymidylate kinase family.

47917:WN53 RS18945
gene id: 47917:WN53_RS18945
uniprot id: A0A0F7HDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

47917:WN53 RS13115
gene id: 47917:WN53_RS13115
uniprot id: A0A0F7HAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

47917:WN53 RS20085
gene id: 47917:WN53_RS20085
uniprot id: A0A0F7HDS7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

47917:WN53 RS13160
gene id: 47917:WN53_RS13160
uniprot id: A0A0F7HB83
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

47917:WN53 RS09870
gene id: 47917:WN53_RS09870
uniprot id: A0A0F7HB78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS22045
gene id: 47917:WN53_RS22045
uniprot id: A0A0F7HGN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

47917:WN53 RS18865
gene id: 47917:WN53_RS18865
uniprot id: A0A0F7HE95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS26545
gene id: 47917:WN53_RS26545
uniprot id: A0A0F7HHM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS11810
gene id: 47917:WN53_RS11810
uniprot id: A0A0F7HAN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

47917:WN53 RS02045
gene id: 47917:WN53_RS02045
uniprot id: A0A0F7H7I9
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS20880
gene id: 47917:WN53_RS20880
uniprot id: A0A0F7HG46
names: Similarity
messages: Belongs to the group II decarboxylase family.

47917:WN53 RS13775
gene id: 47917:WN53_RS13775
uniprot id: A0A0F7HC99
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02990
gene id: 47917:WN53_RS02990
uniprot id: A0A0F7H847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS25600
gene id: 47917:WN53_RS25600
uniprot id: A0A0F7HGE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS22415
gene id: 47917:WN53_RS22415
uniprot id: A0A0F7HGT7
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS27580
gene id: 47917:WN53_RS27580
uniprot id: A0A1Q5VH38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

47917:WN53 RS04440
gene id: 47917:WN53_RS04440
uniprot id: A0A0F7H907
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26630
gene id: 47917:WN53_RS26630
uniprot id: A0A0F7HGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

47917:WN53 RS23955
gene id: 47917:WN53_RS23955
uniprot id: A0A0F7HGK6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

47917:WN53 RS22110
gene id: 47917:WN53_RS22110
uniprot id: A0A0F7HGP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS11995
gene id: 47917:WN53_RS11995
uniprot id: A0A0F7D1Y1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

47917:WN53 RS08985
gene id: 47917:WN53_RS08985
uniprot id: A0A0F7H9D0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

47917:WN53 RS25690
gene id: 47917:WN53_RS25690
uniprot id: A0A0F7HI51
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS19335
gene id: 47917:WN53_RS19335
uniprot id: A0A0F7HDS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

47917:WN53 RS08085
gene id: 47917:WN53_RS08085
uniprot id: A0A0F7H916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS04780
gene id: 47917:WN53_RS04780
uniprot id: A0A0F7H950
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

47917:WN53 RS12350
gene id: 47917:WN53_RS12350
uniprot id: A0A0F7HAQ4
names: Similarity
messages: Belongs to the CdaR family.

47917:WN53 RS13165
gene id: 47917:WN53_RS13165
uniprot id: A0A0F7HB03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

47917:WN53 RS21075
gene id: 47917:WN53_RS21075
uniprot id: A0A0F7HFG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS13970
gene id: 47917:WN53_RS13970
uniprot id: A0A0F7D249
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS07685
gene id: 47917:WN53_RS07685
uniprot id: A0A0F7H947
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

47917:WN53 RS11650
gene id: 47917:WN53_RS11650
uniprot id: A0A0F7HC20
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

47917:WN53 RS13840
gene id: 47917:WN53_RS13840
uniprot id: A0A0F7HIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS05665
gene id: 47917:WN53_RS05665
uniprot id: A0A0F7H9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

47917:WN53 RS20050
gene id: 47917:WN53_RS20050
uniprot id: A0A0F7HDS4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

47917:WN53 RS23365
gene id: 47917:WN53_RS23365
uniprot id: A0A0F7HGB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

47917:WN53 RS17060
gene id: 47917:WN53_RS17060
uniprot id: A0A0F7HDP7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

47917:WN53 RS11000
gene id: 47917:WN53_RS11000
uniprot id: A0A0F7HA26
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

47917:WN53 RS16065
gene id: 47917:WN53_RS16065
uniprot id: A0A0F7HD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS16105
gene id: 47917:WN53_RS16105
uniprot id: A0A0F7HE84
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

47917:WN53 RS26065
gene id: 47917:WN53_RS26065
uniprot id: A0A0F7HG04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

47917:WN53 RS24080
gene id: 47917:WN53_RS24080
uniprot id: A0A0F7D367
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

47917:WN53 RS05365
gene id: 47917:WN53_RS05365
uniprot id: A0A0F7H8W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

47917:WN53 RS19205
gene id: 47917:WN53_RS19205
uniprot id: A0A0F7HER9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

47917:WN53 RS14755
gene id: 47917:WN53_RS14755
uniprot id: A0A0F7HBR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

47917:WN53 RS17180
gene id: 47917:WN53_RS17180
uniprot id: A0A0F7D2G8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

47917:WN53 RS26125
gene id: 47917:WN53_RS26125
uniprot id: A0A0F7D3E0
names: Similarity
messages: Belongs to the UPF0115 family.

47917:WN53 RS14220
gene id: 47917:WN53_RS14220
uniprot id: A0A0F7HCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

47917:WN53 RS24810
gene id: 47917:WN53_RS24810
uniprot id: A0A0F7HFZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19195
gene id: 47917:WN53_RS19195
uniprot id: A0A0F7HDE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

47917:WN53 RS09225
gene id: 47917:WN53_RS09225
uniprot id: A0A0F7HB07
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

47917:WN53 RS20575
gene id: 47917:WN53_RS20575
uniprot id: A0A0F7HE08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS10675
gene id: 47917:WN53_RS10675
uniprot id: A0A0F7HBJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

47917:WN53 RS23825
gene id: 47917:WN53_RS23825
uniprot id: A0A0F7HH41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

47917:WN53 RS04485
gene id: 47917:WN53_RS04485
uniprot id: A0A0F7D163
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS11365
gene id: 47917:WN53_RS11365
uniprot id: A0A0F7HB96
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

47917:WN53 RS22450
gene id: 47917:WN53_RS22450
uniprot id: A0A0F7D310
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

47917:WN53 RS13625
gene id: 47917:WN53_RS13625
uniprot id: A0A0F7HB65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

47917:WN53 RS12725
gene id: 47917:WN53_RS12725
uniprot id: A0A0F7HC19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

47917:WN53 RS19860
gene id: 47917:WN53_RS19860
uniprot id: A0A0F7HGS1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

47917:WN53 RS14185
gene id: 47917:WN53_RS14185
uniprot id: A0A0F7HCI0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

47917:WN53 RS17130
gene id: 47917:WN53_RS17130
uniprot id: A0A0F7D2G6
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

47917:WN53 RS01250
gene id: 47917:WN53_RS01250
uniprot id: A0A0F7H7Q0
names: Similarity
messages: Belongs to the peptidase C40 family.

47917:WN53 RS16680
gene id: 47917:WN53_RS16680
uniprot id: A0A0F7HCD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS10645
gene id: 47917:WN53_RS10645
uniprot id: A0A0F7HBJ7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

47917:WN53 RS25695
gene id: 47917:WN53_RS25695
uniprot id: A0A0F7HFU2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

47917:WN53 RS22475
gene id: 47917:WN53_RS22475
uniprot id: A0A0F7D311
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

47917:WN53 RS22405
gene id: 47917:WN53_RS22405
uniprot id: A0A0F7HG02
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

47917:WN53 RS23585
gene id: 47917:WN53_RS23585
uniprot id: A0A0F7HFF0
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

47917:WN53 RS22015
gene id: 47917:WN53_RS22015
uniprot id: A0A0F7HGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS16710
gene id: 47917:WN53_RS16710
uniprot id: A0A0F7D3J8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04260
gene id: 47917:WN53_RS04260
uniprot id: A0A0F7H8I5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS13575
gene id: 47917:WN53_RS13575
uniprot id: A0A0F7HC73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

47917:WN53 RS10475
gene id: 47917:WN53_RS10475
uniprot id: A0A0F7HA28
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

47917:WN53 RS16725
gene id: 47917:WN53_RS16725
uniprot id: A0A0F7HDJ4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

47917:WN53 RS02415
gene id: 47917:WN53_RS02415
uniprot id: A0A0F7D0Z2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

47917:WN53 RS07755
gene id: 47917:WN53_RS07755
uniprot id: A0A0F7H8Y3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26550
gene id: 47917:WN53_RS26550
uniprot id: A0A0F7HID8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

47917:WN53 RS14740
gene id: 47917:WN53_RS14740
uniprot id: A0A0F7HDR9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00595
gene id: 47917:WN53_RS00595
uniprot id: A0A0F7H731
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

47917:WN53 RS26600
gene id: 47917:WN53_RS26600
uniprot id: A0A0F7HHM4
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS15475
gene id: 47917:WN53_RS15475
uniprot id: A0A0F7HCU2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

47917:WN53 RS21160
gene id: 47917:WN53_RS21160
uniprot id: A0A0F7HEG7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02000
gene id: 47917:WN53_RS02000
uniprot id: A0A0F7D0X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

47917:WN53 RS09365
gene id: 47917:WN53_RS09365
uniprot id: A0A0F7HAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

47917:WN53 RS05800
gene id: 47917:WN53_RS05800
uniprot id: A0A0F7H8C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

47917:WN53 RS17400
gene id: 47917:WN53_RS17400
uniprot id: A0A0F7HCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

47917:WN53 RS19050
gene id: 47917:WN53_RS19050
uniprot id: A0A0F7HEM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

47917:WN53 RS07855
gene id: 47917:WN53_RS07855
uniprot id: A0A0F7H8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS13765
gene id: 47917:WN53_RS13765
uniprot id: A0A0F7HCE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS15350
gene id: 47917:WN53_RS15350
uniprot id: A0A0F7D2A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

47917:WN53 RS15840
gene id: 47917:WN53_RS15840
uniprot id: A0A0F7D2B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

47917:WN53 RS05360
gene id: 47917:WN53_RS05360
uniprot id: A0A0F7H909
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

47917:WN53 RS17340
gene id: 47917:WN53_RS17340
uniprot id: A0A0F7HCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

47917:WN53 RS02650
gene id: 47917:WN53_RS02650
uniprot id: A0A0F7H6T4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

47917:WN53 RS06515
gene id: 47917:WN53_RS06515
uniprot id: A0A0F7H9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

47917:WN53 RS11960
gene id: 47917:WN53_RS11960
uniprot id: A0A0F7HBH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

47917:WN53 RS08065
gene id: 47917:WN53_RS08065
uniprot id: A0A0F7HA31
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS12740
gene id: 47917:WN53_RS12740
uniprot id: A0A0F7HCN7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

47917:WN53 RS00185
gene id: 47917:WN53_RS00185
uniprot id: A0A0F7H5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

47917:WN53 RS22225
gene id: 47917:WN53_RS22225
uniprot id: A0A0F7HF01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

47917:WN53 RS17795
gene id: 47917:WN53_RS17795
uniprot id: A0A0F7D2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS06395
gene id: 47917:WN53_RS06395
uniprot id: A0A0F7D1D4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS01640
gene id: 47917:WN53_RS01640
uniprot id: A0A0F7H6D7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

47917:WN53 RS23850
gene id: 47917:WN53_RS23850
uniprot id: A0A0F7HGW5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

47917:WN53 RS20970
gene id: 47917:WN53_RS20970
uniprot id: A0A0F7HEC5
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

47917:WN53 RS11860
gene id: 47917:WN53_RS11860
uniprot id: A0A0F7HBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

47917:WN53 RS17865
gene id: 47917:WN53_RS17865
uniprot id: A0A0F7HDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

47917:WN53 RS13555
gene id: 47917:WN53_RS13555
uniprot id: A0A0F7HBB4
names: Similarity
messages: Belongs to the YkuD family.

47917:WN53 RS21930
gene id: 47917:WN53_RS21930
uniprot id: A0A0F7HEW1
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS11095
gene id: 47917:WN53_RS11095
uniprot id: A0A0F7HA36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

47917:WN53 RS06945
gene id: 47917:WN53_RS06945
uniprot id: A0A0F7H9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

47917:WN53 RS04390
gene id: 47917:WN53_RS04390
uniprot id: A0A0F7H8P8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

47917:WN53 RS26120
gene id: 47917:WN53_RS26120
uniprot id: A0A0F7HI97
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

47917:WN53 RS16810
gene id: 47917:WN53_RS16810
uniprot id: A0A0F7HCP5
names: Similarity
messages: Belongs to the EcpB/EcpE family.

47917:WN53 RS25105
gene id: 47917:WN53_RS25105
uniprot id: A0A0F7HH69
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14245
gene id: 47917:WN53_RS14245
uniprot id: A0A0F7HBG0
names: Similarity
messages: Belongs to the UPF0234 family.

47917:WN53 RS10135
gene id: 47917:WN53_RS10135
uniprot id: A0A0F7HBD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

47917:WN53 RS18765
gene id: 47917:WN53_RS18765
uniprot id: A0A0F7D2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS01855
gene id: 47917:WN53_RS01855
uniprot id: A0A0F7HGB4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

47917:WN53 RS14270
gene id: 47917:WN53_RS14270
uniprot id: A0A0F7HBJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

47917:WN53 RS20685
gene id: 47917:WN53_RS20685
uniprot id: A0A0F7D2U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

47917:WN53 RS08965
gene id: 47917:WN53_RS08965
uniprot id: A0A0F7HAB0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06810
gene id: 47917:WN53_RS06810
uniprot id: A0A0F7H8F5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

47917:WN53 RS00440
gene id: 47917:WN53_RS00440
uniprot id: A0A0F7H708
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

47917:WN53 RS04300
gene id: 47917:WN53_RS04300
uniprot id: A0A0F7H8I9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

47917:WN53 RS13190
gene id: 47917:WN53_RS13190
uniprot id: A0A0F7HCY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

47917:WN53 RS08335
gene id: 47917:WN53_RS08335
uniprot id: A0A0F7D3H9
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

47917:WN53 RS00585
gene id: 47917:WN53_RS00585
uniprot id: A0A0F7H753
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26985
gene id: 47917:WN53_RS26985
uniprot id: A0A0U4A2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

47917:WN53 RS10840
gene id: 47917:WN53_RS10840
uniprot id: A0A0F7HA69
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

47917:WN53 RS02425
gene id: 47917:WN53_RS02425
uniprot id: A0A0F7HF22
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

47917:WN53 RS00980
gene id: 47917:WN53_RS00980
uniprot id: A0A0F7H7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

47917:WN53 RS14055
gene id: 47917:WN53_RS14055
uniprot id: A0A0F7HCF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

47917:WN53 RS21575
gene id: 47917:WN53_RS21575
uniprot id: A0A0F7HFM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
messages: Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS14530
gene id: 47917:WN53_RS14530
uniprot id: A0A0F7HBN3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

47917:WN53 RS25560
gene id: 47917:WN53_RS25560
uniprot id: A0A0F7D3B9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS16720
gene id: 47917:WN53_RS16720
uniprot id: A0A0F7HI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

47917:WN53 RS15535
gene id: 47917:WN53_RS15535
uniprot id: A0A0F7HD47
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS24095
gene id: 47917:WN53_RS24095
uniprot id: A0A0F7HF82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

47917:WN53 RS10635
gene id: 47917:WN53_RS10635
uniprot id: A0A0F7HAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

47917:WN53 RS25820
gene id: 47917:WN53_RS25820
uniprot id: A0A0F7HI70
names: Similarity
messages: Belongs to the intimin/invasin family.

47917:WN53 RS26185
gene id: 47917:WN53_RS26185
uniprot id: A0A0F7D3E2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

47917:WN53 RS05075
gene id: 47917:WN53_RS05075
uniprot id: A0A0F7D185
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20020
gene id: 47917:WN53_RS20020
uniprot id: A0A0F7HE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS14070
gene id: 47917:WN53_RS14070
uniprot id: A0A0F7HBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

47917:WN53 RS11685
gene id: 47917:WN53_RS11685
uniprot id: A0A0F7HAL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

47917:WN53 RS17925
gene id: 47917:WN53_RS17925
uniprot id: A0A0F7HE37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS26195
gene id: 47917:WN53_RS26195
uniprot id: A0A0F7HI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS21865
gene id: 47917:WN53_RS21865
uniprot id: A0A0F7D2Y8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19330
gene id: 47917:WN53_RS19330
uniprot id: A0A0F7HDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS15795
gene id: 47917:WN53_RS15795
uniprot id: A0A0F7HC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS00175
gene id: 47917:WN53_RS00175
uniprot id: A0A0F7H6S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

47917:WN53 RS12660
gene id: 47917:WN53_RS12660
uniprot id: A0A0F7HCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS03370
gene id: 47917:WN53_RS03370
uniprot id: A0A0F7H7B0
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

47917:WN53 RS05585
gene id: 47917:WN53_RS05585
uniprot id: A0A0F7H7Y0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

47917:WN53 RS23675
gene id: 47917:WN53_RS23675
uniprot id: A0A0F7HH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS26655
gene id: 47917:WN53_RS26655
uniprot id: A0A0F7HIF2
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

47917:WN53 RS14440
gene id: 47917:WN53_RS14440
uniprot id: A0A0F7HCL3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS25670
gene id: 47917:WN53_RS25670
uniprot id: A0A0F7D3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS18840
gene id: 47917:WN53_RS18840
uniprot id: A0A0F7HDC0
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

47917:WN53 RS22980
gene id: 47917:WN53_RS22980
uniprot id: A0A0F7HG93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

47917:WN53 RS10530
gene id: 47917:WN53_RS10530
uniprot id: A0A0F7D1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS21780
gene id: 47917:WN53_RS21780
uniprot id: A0A0F7HEJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

47917:WN53 RS00900
gene id: 47917:WN53_RS00900
uniprot id: A0A0F7H767
names: Similarity
messages: Belongs to the P(II) protein family.

47917:WN53 RS16025
gene id: 47917:WN53_RS16025
uniprot id: A0A0F7HC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

47917:WN53 RS12020
gene id: 47917:WN53_RS12020
uniprot id: A0A0F7D1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

47917:WN53 RS06020
gene id: 47917:WN53_RS06020
uniprot id: A0A0F7H8F1
names: Similarity
messages: Belongs to the UPF0270 family.

47917:WN53 RS05500
gene id: 47917:WN53_RS05500
uniprot id: A0A0F7H9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS26150
gene id: 47917:WN53_RS26150
uniprot id: A0A0F7D3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

47917:WN53 RS14370
gene id: 47917:WN53_RS14370
uniprot id: A0A0F7HBI6
names: Similarity
messages: Belongs to the P(II) protein family.

47917:WN53 RS02825
gene id: 47917:WN53_RS02825
uniprot id: A0A0F7H6W1
names: Similarity
messages: Belongs to the UPF0231 family.

47917:WN53 RS06815
gene id: 47917:WN53_RS06815
uniprot id: A0A0F7H9M1
names: Similarity
messages: Belongs to the UPF0438 family.

47917:WN53 RS12770
gene id: 47917:WN53_RS12770
uniprot id: A0A0F7D208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS04370
gene id: 47917:WN53_RS04370
uniprot id: A0A0F7H8Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

47917:WN53 RS01795
gene id: 47917:WN53_RS01795
uniprot id: A0A0F7H6G2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

47917:WN53 RS19655
gene id: 47917:WN53_RS19655
uniprot id: A0A0F7HF02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

47917:WN53 RS26380
gene id: 47917:WN53_RS26380
uniprot id: A0A0F7D3E9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

47917:WN53 RS07485
gene id: 47917:WN53_RS07485
uniprot id: A0A0F7H9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

47917:WN53 RS05615
gene id: 47917:WN53_RS05615
uniprot id: A0A0F7H7Y6
names: Similarity
messages: Belongs to the malate synthase family.

47917:WN53 RS01175
gene id: 47917:WN53_RS01175
uniprot id: A0A0F7H6H8
names: Similarity
messages: Belongs to the Gfa family.

47917:WN53 RS17880
gene id: 47917:WN53_RS17880
uniprot id: A0A0F7HCZ1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

47917:WN53 RS16320
gene id: 47917:WN53_RS16320
uniprot id: A0A0F7HDF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04555
gene id: 47917:WN53_RS04555
uniprot id: A0A0F7H8S3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07000
gene id: 47917:WN53_RS07000
uniprot id: A0A0F7H8H5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

47917:WN53 RS14710
gene id: 47917:WN53_RS14710
uniprot id: A0A0F7HDQ9
names: Similarity
messages: Belongs to the carbamate kinase family.

47917:WN53 RS23130
gene id: 47917:WN53_RS23130
uniprot id: A0A0F7D333
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

47917:WN53 RS02105
gene id: 47917:WN53_RS02105
uniprot id: A0A0F7H7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS15460
gene id: 47917:WN53_RS15460
uniprot id: A0A0F7HC55
names: Similarity
messages: Belongs to the PhoH family.

47917:WN53 RS22170
gene id: 47917:WN53_RS22170
uniprot id: A0A0F7HFX0
names: Similarity
messages: Belongs to the YciI family.

47917:WN53 RS15385
gene id: 47917:WN53_RS15385
uniprot id: A0A0F7HCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

47917:WN53 RS03275
gene id: 47917:WN53_RS03275
uniprot id: A0A0F7H810
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

47917:WN53 RS11725
gene id: 47917:WN53_RS11725
uniprot id: A0A0F7HAG9
names: Similarity
messages: Belongs to the threonine synthase family.

47917:WN53 RS26570
gene id: 47917:WN53_RS26570
uniprot id: A0A0F7HHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

47917:WN53 RS09245
gene id: 47917:WN53_RS09245
uniprot id: A0A0F7D1N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

47917:WN53 RS17185
gene id: 47917:WN53_RS17185
uniprot id: A0A0F7HDU0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

47917:WN53 RS02635
gene id: 47917:WN53_RS02635
uniprot id: A0A0F7H895
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

47917:WN53 RS04180
gene id: 47917:WN53_RS04180
uniprot id: A0A0F7H7P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

47917:WN53 RS24960
gene id: 47917:WN53_RS24960
uniprot id: A0A0F7HGY2
names: Similarity
messages: Belongs to the glutamine synthetase family.

47917:WN53 RS04835
gene id: 47917:WN53_RS04835
uniprot id: A0A0F7H8U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

47917:WN53 RS15920
gene id: 47917:WN53_RS15920
uniprot id: A0A0F7D2C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS25760
gene id: 47917:WN53_RS25760
uniprot id: A0A0F7HI61
names: Similarity
messages: Belongs to the Nudix hydrolase family.

47917:WN53 RS21985
gene id: 47917:WN53_RS21985
uniprot id: A0A0F7HEK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

47917:WN53 RS04265
gene id: 47917:WN53_RS04265
uniprot id: A0A0F7H8Y5
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS12080
gene id: 47917:WN53_RS12080
uniprot id: A0A0F7HBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

47917:WN53 RS05730
gene id: 47917:WN53_RS05730
uniprot id: A0A0F7H9I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

47917:WN53 RS04060
gene id: 47917:WN53_RS04060
uniprot id: A0A0F7D147
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS11130
gene id: 47917:WN53_RS11130
uniprot id: A0A0F7D1U9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

47917:WN53 RS12110
gene id: 47917:WN53_RS12110
uniprot id: A0A0F7HBU6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

47917:WN53 RS07665
gene id: 47917:WN53_RS07665
uniprot id: A0A0F7HA58
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

47917:WN53 RS03415
gene id: 47917:WN53_RS03415
uniprot id: A0A0F7H714
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

47917:WN53 RS06900
gene id: 47917:WN53_RS06900
uniprot id: A0A0F7H8Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

47917:WN53 RS10420
gene id: 47917:WN53_RS10420
uniprot id: A0A0F7D1S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

47917:WN53 RS11355
gene id: 47917:WN53_RS11355
uniprot id: A0A0F7HBM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS11290
gene id: 47917:WN53_RS11290
uniprot id: A0A0F7HH60
names: Similarity
messages: Belongs to the EcpB/EcpE family.

47917:WN53 RS05345
gene id: 47917:WN53_RS05345
uniprot id: A0A0F7D195
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS07250
gene id: 47917:WN53_RS07250
uniprot id: A0A0F7H8V1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

47917:WN53 RS03375
gene id: 47917:WN53_RS03375
uniprot id: A0A0F7H710
names: Similarity
messages: Belongs to the PhzF family.

47917:WN53 RS06210
gene id: 47917:WN53_RS06210
uniprot id: A0A0F7H980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

47917:WN53 RS07690
gene id: 47917:WN53_RS07690
uniprot id: A0A0F7H8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

47917:WN53 RS00895
gene id: 47917:WN53_RS00895
uniprot id: A0A0F7H7A4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS15885
gene id: 47917:WN53_RS15885
uniprot id: A0A0F7HE55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cell membrane
messages: Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc.
messages: Membrane

47917:WN53 RS12985
gene id: 47917:WN53_RS12985
uniprot id: A0A0F7HBZ1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23165
gene id: 47917:WN53_RS23165
uniprot id: A0A0F7HG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

47917:WN53 RS25200
gene id: 47917:WN53_RS25200
uniprot id: A0A0F7HG90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS02720
gene id: 47917:WN53_RS02720
uniprot id: A0A0F7H6U4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

47917:WN53 RS19975
gene id: 47917:WN53_RS19975
uniprot id: A0A0F7D2S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

47917:WN53 RS19785
gene id: 47917:WN53_RS19785
uniprot id: A0A0F7D2R3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04695
gene id: 47917:WN53_RS04695
uniprot id: A0A0F7D171
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

47917:WN53 RS08045
gene id: 47917:WN53_RS08045
uniprot id: A0A0F7H914
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS17930
gene id: 47917:WN53_RS17930
uniprot id: A0A0F7D2J7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

47917:WN53 RS12895
gene id: 47917:WN53_RS12895
uniprot id: A0A0F7HAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS20580
gene id: 47917:WN53_RS20580
uniprot id: A0A0F7HE71
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20360
gene id: 47917:WN53_RS20360
uniprot id: A0A0F7HDV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

47917:WN53 RS01905
gene id: 47917:WN53_RS01905
uniprot id: A0A0F7H7I0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

47917:WN53 RS19750
gene id: 47917:WN53_RS19750
uniprot id: A0A0F7HDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

47917:WN53 RS09880
gene id: 47917:WN53_RS09880
uniprot id: A0A0F7D1Q4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

47917:WN53 RS19070
gene id: 47917:WN53_RS19070
uniprot id: A0A0F7HDC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

47917:WN53 RS08305
gene id: 47917:WN53_RS08305
uniprot id: A0A0F7H948
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS10305
gene id: 47917:WN53_RS10305
uniprot id: A0A0F7HAQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

47917:WN53 RS03025
gene id: 47917:WN53_RS03025
uniprot id: A0A0F7H7X7
names: Similarity
messages: Belongs to the YggT family.

47917:WN53 RS02710
gene id: 47917:WN53_RS02710
uniprot id: A0A0F7H8A8
names: Similarity
messages: Belongs to the SfsA family.

47917:WN53 RS12370
gene id: 47917:WN53_RS12370
uniprot id: A0A0F7D1Z5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS09390
gene id: 47917:WN53_RS09390
uniprot id: A0A0F7HAS3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

47917:WN53 RS15585
gene id: 47917:WN53_RS15585
uniprot id: A0A0F7HE03
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

47917:WN53 RS07115
gene id: 47917:WN53_RS07115
uniprot id: A0A0F7HA40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

47917:WN53 RS24995
gene id: 47917:WN53_RS24995
uniprot id: A0A0F7HGZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS18810
gene id: 47917:WN53_RS18810
uniprot id: A0A0F7HDI5
names: Similarity
messages: Belongs to the HupJ family.

47917:WN53 RS07175
gene id: 47917:WN53_RS07175
uniprot id: A0A0F7H9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

47917:WN53 RS00800
gene id: 47917:WN53_RS00800
uniprot id: A0A0F7H7J1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

47917:WN53 RS06230
gene id: 47917:WN53_RS06230
uniprot id: A0A0F7D1C8
names: Similarity
messages: Belongs to the HSP15 family.

47917:WN53 RS05745
gene id: 47917:WN53_RS05745
uniprot id: A0A0F7H7Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

47917:WN53 RS02880
gene id: 47917:WN53_RS02880
uniprot id: A0A0F7H750
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

47917:WN53 RS20370
gene id: 47917:WN53_RS20370
uniprot id: A0A0F7HE46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

47917:WN53 RS20615
gene id: 47917:WN53_RS20615
uniprot id: A0A0F7HE13
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07795
gene id: 47917:WN53_RS07795
uniprot id: A0A0F7HA86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

47917:WN53 RS22325
gene id: 47917:WN53_RS22325
uniprot id: A0A0F7HEN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

47917:WN53 RS21150
gene id: 47917:WN53_RS21150
uniprot id: A0A0F7HG54
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

47917:WN53 RS17115
gene id: 47917:WN53_RS17115
uniprot id: A0A0F7HCU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS19955
gene id: 47917:WN53_RS19955
uniprot id: A0A0F7HI62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS25460
gene id: 47917:WN53_RS25460
uniprot id: A0A0F7HGA6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

47917:WN53 RS16685
gene id: 47917:WN53_RS16685
uniprot id: A0A0F7HDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS10190
gene id: 47917:WN53_RS10190
uniprot id: A0A0F7HB45
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

47917:WN53 RS09250
gene id: 47917:WN53_RS09250
uniprot id: A0A0F7HAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

47917:WN53 RS20280
gene id: 47917:WN53_RS20280
uniprot id: A0A0F7D2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS10140
gene id: 47917:WN53_RS10140
uniprot id: A0A0F7H9Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

47917:WN53 RS07760
gene id: 47917:WN53_RS07760
uniprot id: A0A0F7D1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

47917:WN53 RS10180
gene id: 47917:WN53_RS10180
uniprot id: A0A0F7D1R4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

47917:WN53 RS13620
gene id: 47917:WN53_RS13620
uniprot id: A0A0F7HBC3
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

47917:WN53 RS22815
gene id: 47917:WN53_RS22815
uniprot id: A0A0F7HF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

47917:WN53 RS27830
gene id: 47917:WN53_RS27830
uniprot id: A0A0F7H912
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS17830
gene id: 47917:WN53_RS17830
uniprot id: A0A0F7HE26
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24840
gene id: 47917:WN53_RS24840
uniprot id: A0A0F7HFG3
names: Similarity
messages: Belongs to the hyi family.

47917:WN53 RS09680
gene id: 47917:WN53_RS09680
uniprot id: A0A0F7D1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

47917:WN53 RS24130
gene id: 47917:WN53_RS24130
uniprot id: A0A0F7HHD0
names: Similarity
messages: Belongs to the group II decarboxylase family.

47917:WN53 RS17890
gene id: 47917:WN53_RS17890
uniprot id: A0A0F7HE32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

47917:WN53 RS22790
gene id: 47917:WN53_RS22790
uniprot id: A0A0F7HG68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

47917:WN53 RS00425
gene id: 47917:WN53_RS00425
uniprot id: A0A0F7H7C5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

47917:WN53 RS06110
gene id: 47917:WN53_RS06110
uniprot id: A0A0F7H9P1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

47917:WN53 RS01920
gene id: 47917:WN53_RS01920
uniprot id: A0A0F7D0X5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS21960
gene id: 47917:WN53_RS21960
uniprot id: A0A0F7HEW4
names: Similarity
messages: Belongs to the SUI1 family.

47917:WN53 RS16625
gene id: 47917:WN53_RS16625
uniprot id: A0A0F7HEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

47917:WN53 RS21795
gene id: 47917:WN53_RS21795
uniprot id: A0A0F7HFQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

47917:WN53 RS09825
gene id: 47917:WN53_RS09825
uniprot id: A0A0F7H9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

47917:WN53 RS20005
gene id: 47917:WN53_RS20005
uniprot id: A0A0F7D2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

47917:WN53 RS03155
gene id: 47917:WN53_RS03155
uniprot id: A0A0F7H6Z0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS15335
gene id: 47917:WN53_RS15335
uniprot id: A0A0F7HBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

47917:WN53 RS04815
gene id: 47917:WN53_RS04815
uniprot id: A0A0F7D175
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

47917:WN53 RS16545
gene id: 47917:WN53_RS16545
uniprot id: A0A0F7HCC3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

47917:WN53 RS20355
gene id: 47917:WN53_RS20355
uniprot id: A0A0F7HFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

47917:WN53 RS23780
gene id: 47917:WN53_RS23780
uniprot id: A0A0F7HGI5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

47917:WN53 RS06555
gene id: 47917:WN53_RS06555
uniprot id: A0A0F7H9V4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

47917:WN53 RS01710
gene id: 47917:WN53_RS01710
uniprot id: A0A0F7H7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

47917:WN53 RS23015
gene id: 47917:WN53_RS23015
uniprot id: A0A0F7HG77
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

47917:WN53 RS10865
gene id: 47917:WN53_RS10865
uniprot id: A0A0F7HBL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

47917:WN53 RS23705
gene id: 47917:WN53_RS23705
uniprot id: A0A0F7HGF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS11435
gene id: 47917:WN53_RS11435
uniprot id: A0A0F7HBY8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00855
gene id: 47917:WN53_RS00855
uniprot id: A0A0F7H622
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

47917:WN53 RS23350
gene id: 47917:WN53_RS23350
uniprot id: A0A0F7D340
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

47917:WN53 RS05835
gene id: 47917:WN53_RS05835
uniprot id: A0A0F7H814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

47917:WN53 RS22180
gene id: 47917:WN53_RS22180
uniprot id: A0A0F7HGQ5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25770
gene id: 47917:WN53_RS25770
uniprot id: A0A0F7HGF6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

47917:WN53 RS27835
gene id: 47917:WN53_RS27835
uniprot id: A0A0F7D1B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

47917:WN53 RS08060
gene id: 47917:WN53_RS08060
uniprot id: A0A0F7HAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS05250
gene id: 47917:WN53_RS05250
uniprot id: A0A0F7H848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

47917:WN53 RS12045
gene id: 47917:WN53_RS12045
uniprot id: A0A0F7D1Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

47917:WN53 RS17010
gene id: 47917:WN53_RS17010
uniprot id: A0A0F7HCR0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

47917:WN53 RS18870
gene id: 47917:WN53_RS18870
uniprot id: A0A0F7HFB7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

47917:WN53 RS25430
gene id: 47917:WN53_RS25430
uniprot id: A0A0F7HID6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

47917:WN53 RS16225
gene id: 47917:WN53_RS16225
uniprot id: A0A0F7HDD8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02335
gene id: 47917:WN53_RS02335
uniprot id: A0A0F7HGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

47917:WN53 RS22470
gene id: 47917:WN53_RS22470
uniprot id: A0A0F7HG20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

47917:WN53 RS25115
gene id: 47917:WN53_RS25115
uniprot id: A0A0F7HFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS22250
gene id: 47917:WN53_RS22250
uniprot id: A0A0F7HEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

47917:WN53 RS12310
gene id: 47917:WN53_RS12310
uniprot id: A0A0F7HAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

47917:WN53 RS14165
gene id: 47917:WN53_RS14165
uniprot id: A0A0F7HDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

47917:WN53 RS09725
gene id: 47917:WN53_RS09725
uniprot id: A0A0F7HAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

47917:WN53 RS23135
gene id: 47917:WN53_RS23135
uniprot id: A0A0F7HG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

47917:WN53 RS22515
gene id: 47917:WN53_RS22515
uniprot id: A0A0F7HEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

47917:WN53 RS16385
gene id: 47917:WN53_RS16385
uniprot id: A0A0F7D2D8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

47917:WN53 RS22660
gene id: 47917:WN53_RS22660
uniprot id: A0A0F7HG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS08235
gene id: 47917:WN53_RS08235
uniprot id: A0A0F7H9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

47917:WN53 RS21495
gene id: 47917:WN53_RS21495
uniprot id: A0A0F7HEK6
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

47917:WN53 RS18385
gene id: 47917:WN53_RS18385
uniprot id: A0A0F7D2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS20350
gene id: 47917:WN53_RS20350
uniprot id: A0A0F7HF00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

47917:WN53 RS00785
gene id: 47917:WN53_RS00785
uniprot id: A0A0F7H613
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

47917:WN53 RS02780
gene id: 47917:WN53_RS02780
uniprot id: A0A1Q5VES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

47917:WN53 RS04600
gene id: 47917:WN53_RS04600
uniprot id: A0A0F7H8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

47917:WN53 RS11880
gene id: 47917:WN53_RS11880
uniprot id: A0A0F7HAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

47917:WN53 RS20255
gene id: 47917:WN53_RS20255
uniprot id: A0A0F7D2T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

47917:WN53 RS09190
gene id: 47917:WN53_RS09190
uniprot id: A0A0F7D1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

47917:WN53 RS10070
gene id: 47917:WN53_RS10070
uniprot id: A0A0F7H9Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase.
messages: Binds 1 FMN per monomer.
messages: Binds 3 Fe cations per monomer.
messages: Cytoplasm
messages: Homotetramer.
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

47917:WN53 RS25000
gene id: 47917:WN53_RS25000
uniprot id: A0A0F7HH34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

47917:WN53 RS19815
gene id: 47917:WN53_RS19815
uniprot id: A0A0F7HDY4
names: Similarity
messages: Belongs to the fructosamine kinase family.

47917:WN53 RS20905
gene id: 47917:WN53_RS20905
uniprot id: A0A0F7HFF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS24955
gene id: 47917:WN53_RS24955
uniprot id: A0A0F7D398
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS21410
gene id: 47917:WN53_RS21410
uniprot id: A0A0F7D2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

47917:WN53 RS03185
gene id: 47917:WN53_RS03185
uniprot id: A0A0F7HHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS11395
gene id: 47917:WN53_RS11395
uniprot id: A0A0F7HBB7
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

47917:WN53 RS02005
gene id: 47917:WN53_RS02005
uniprot id: A0A0F7H7Q2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS14635
gene id: 47917:WN53_RS14635
uniprot id: A0A0F7HCN5
names: Similarity
messages: Belongs to the TPP enzyme family.

47917:WN53 RS09490
gene id: 47917:WN53_RS09490
uniprot id: A0A0F7H9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

47917:WN53 RS21120
gene id: 47917:WN53_RS21120
uniprot id: A0A0F7HG53
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS07110
gene id: 47917:WN53_RS07110
uniprot id: A0A0F7H9Q0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS20390
gene id: 47917:WN53_RS20390
uniprot id: A0A0F7D2T5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

47917:WN53 RS17915
gene id: 47917:WN53_RS17915
uniprot id: A0A0F7HD46
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

47917:WN53 RS05775
gene id: 47917:WN53_RS05775
uniprot id: A0A0F7H803
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

47917:WN53 RS05915
gene id: 47917:WN53_RS05915
uniprot id: A0A0F7D1B6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

47917:WN53 RS03770
gene id: 47917:WN53_RS03770
uniprot id: A0A0F7H8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

47917:WN53 RS04760
gene id: 47917:WN53_RS04760
uniprot id: A0A0F7H7M1
names: Similarity
messages: Belongs to the BolA/IbaG family.

47917:WN53 RS23045
gene id: 47917:WN53_RS23045
uniprot id: A0A0F7HEV3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

47917:WN53 RS15665
gene id: 47917:WN53_RS15665
uniprot id: A0A0F7HBZ7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24120
gene id: 47917:WN53_RS24120
uniprot id: A0A0F7HGL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS23635
gene id: 47917:WN53_RS23635
uniprot id: A0A0F7HGH3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01420
gene id: 47917:WN53_RS01420
uniprot id: A0A0F7H6A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

47917:WN53 RS09835
gene id: 47917:WN53_RS09835
uniprot id: A0A0F7D1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

47917:WN53 RS17255
gene id: 47917:WN53_RS17255
uniprot id: A0A0F7D2H1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

47917:WN53 RS03620
gene id: 47917:WN53_RS03620
uniprot id: A0A0F7H8M2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

47917:WN53 RS12170
gene id: 47917:WN53_RS12170
uniprot id: A0A0F7D1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS22760
gene id: 47917:WN53_RS22760
uniprot id: A0A0F7D321
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS14290
gene id: 47917:WN53_RS14290
uniprot id: A0A0F7D261
names: Similarity
messages: Belongs to the BolA/IbaG family.

47917:WN53 RS04810
gene id: 47917:WN53_RS04810
uniprot id: A0A0F7H955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

47917:WN53 RS00385
gene id: 47917:WN53_RS00385
uniprot id: A0A0F7H6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS23330
gene id: 47917:WN53_RS23330
uniprot id: A0A0F7HFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

47917:WN53 RS24775
gene id: 47917:WN53_RS24775
uniprot id: A0A0F7HFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

47917:WN53 RS12525
gene id: 47917:WN53_RS12525
uniprot id: A0A0F7HCM1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

47917:WN53 RS18950
gene id: 47917:WN53_RS18950
uniprot id: A0A0F7D2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

47917:WN53 RS17745
gene id: 47917:WN53_RS17745
uniprot id: A0A0F7D2J0
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

47917:WN53 RS04290
gene id: 47917:WN53_RS04290
uniprot id: A0A0F7HGD6
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

47917:WN53 RS25510
gene id: 47917:WN53_RS25510
uniprot id: A0A0F7HHB2
names: Similarity
messages: Belongs to the catalase family.

47917:WN53 RS21880
gene id: 47917:WN53_RS21880
uniprot id: A0A0F7HGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS10535
gene id: 47917:WN53_RS10535
uniprot id: A0A0F7HAU6
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS06350
gene id: 47917:WN53_RS06350
uniprot id: A0A0F7HHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

47917:WN53 RS13100
gene id: 47917:WN53_RS13100
uniprot id: A0A0F7HCV1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS03655
gene id: 47917:WN53_RS03655
uniprot id: A0A0F7D135
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

47917:WN53 RS00845
gene id: 47917:WN53_RS00845
uniprot id: A0A0F7H7J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS22860
gene id: 47917:WN53_RS22860
uniprot id: A0A0F7D324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

47917:WN53 RS05400
gene id: 47917:WN53_RS05400
uniprot id: A0A0F7H8W5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

47917:WN53 RS22150
gene id: 47917:WN53_RS22150
uniprot id: A0A0F7HGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

47917:WN53 RS21545
gene id: 47917:WN53_RS21545
uniprot id: A0A0F7HGF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

47917:WN53 RS25495
gene id: 47917:WN53_RS25495
uniprot id: A0A0F7HGB0
names: Similarity
messages: Belongs to the CinA family.

47917:WN53 RS13240
gene id: 47917:WN53_RS13240
uniprot id: A0A0F7HC79
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

47917:WN53 RS17095
gene id: 47917:WN53_RS17095
uniprot id: A0A0F7HDH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

47917:WN53 RS19385
gene id: 47917:WN53_RS19385
uniprot id: A0A0F7HFL4
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS12580
gene id: 47917:WN53_RS12580
uniprot id: A0A0F7HAT2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

47917:WN53 RS18070
gene id: 47917:WN53_RS18070
uniprot id: A0A3S4Y2V0
names: Similarity
messages: Belongs to the UPF0319 family.

47917:WN53 RS24875
gene id: 47917:WN53_RS24875
uniprot id: A0A0F7D395
names: Similarity
messages: Belongs to the UPF0423 family.

47917:WN53 RS05180
gene id: 47917:WN53_RS05180
uniprot id: A0A0F7H838
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

47917:WN53 RS05155
gene id: 47917:WN53_RS05155
uniprot id: A0A0F7H7S0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

47917:WN53 RS07580
gene id: 47917:WN53_RS07580
uniprot id: A0A3S5F3K2
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

47917:WN53 RS25140
gene id: 47917:WN53_RS25140
uniprot id: A0A0F7HHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS01660
gene id: 47917:WN53_RS01660
uniprot id: A0A0F7H7V8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

47917:WN53 RS10490
gene id: 47917:WN53_RS10490
uniprot id: A0A0F7HAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

47917:WN53 RS26095
gene id: 47917:WN53_RS26095
uniprot id: A0A0F7HG09
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

47917:WN53 RS22335
gene id: 47917:WN53_RS22335
uniprot id: A0A0F7HFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

47917:WN53 RS01685
gene id: 47917:WN53_RS01685
uniprot id: A0A0F7H7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

47917:WN53 RS06625
gene id: 47917:WN53_RS06625
uniprot id: A0A0F7H8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS23755
gene id: 47917:WN53_RS23755
uniprot id: A0A0F7HH38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane
messages: Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Uptake of Fe(2+) ions across the membrane.

47917:WN53 RS07200
gene id: 47917:WN53_RS07200
uniprot id: A0A0F7H9T0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

47917:WN53 RS23765
gene id: 47917:WN53_RS23765
uniprot id: A0A0F7HF41
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

47917:WN53 RS25145
gene id: 47917:WN53_RS25145
uniprot id: A0A0F7D3A5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

47917:WN53 RS23320
gene id: 47917:WN53_RS23320
uniprot id: A0A0F7HEY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

47917:WN53 RS20075
gene id: 47917:WN53_RS20075
uniprot id: A0A0F7HEV9
names: Similarity
messages: Belongs to the HesB/IscA family.

47917:WN53 RS06980
gene id: 47917:WN53_RS06980
uniprot id: A0A0F7H9M9
names: Similarity
messages: Belongs to the asparaginase 1 family.

47917:WN53 RS15160
gene id: 47917:WN53_RS15160
uniprot id: A0A0F7HDW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
messages: Homotetramer.

47917:WN53 RS19095
gene id: 47917:WN53_RS19095
uniprot id: A0A0F7HFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

47917:WN53 RS21440
gene id: 47917:WN53_RS21440
uniprot id: A0A0F7D2X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

47917:WN53 RS26390
gene id: 47917:WN53_RS26390
uniprot id: A0A0F7HHL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS09705
gene id: 47917:WN53_RS09705
uniprot id: A0A0F7HB56
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

47917:WN53 RS06440
gene id: 47917:WN53_RS06440
uniprot id: A0A0F7H9G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

47917:WN53 RS07340
gene id: 47917:WN53_RS07340
uniprot id: A0A0F7H8W2
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

47917:WN53 RS04340
gene id: 47917:WN53_RS04340
uniprot id: A0A0F7H8Z3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14135
gene id: 47917:WN53_RS14135
uniprot id: A0A0F7HBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

47917:WN53 RS11420
gene id: 47917:WN53_RS11420
uniprot id: A0A0F7HAD0
names: Similarity
messages: Belongs to the histone deacetylase family.

47917:WN53 RS16325
gene id: 47917:WN53_RS16325
uniprot id: A0A0F7HD65
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14965
gene id: 47917:WN53_RS14965
uniprot id: A0A0F7HBV1
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

47917:WN53 RS07620
gene id: 47917:WN53_RS07620
uniprot id: A0A0F7HHV8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

47917:WN53 RS09990
gene id: 47917:WN53_RS09990
uniprot id: A0A0F7D1Q8
names: Similarity
messages: Belongs to the GARS family.

47917:WN53 RS05660
gene id: 47917:WN53_RS05660
uniprot id: A0A0F7D1A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

47917:WN53 RS11375
gene id: 47917:WN53_RS11375
uniprot id: A0A0F7HF22
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

47917:WN53 RS06475
gene id: 47917:WN53_RS06475
uniprot id: A0A0F7D1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

47917:WN53 RS09435
gene id: 47917:WN53_RS09435
uniprot id: A0A0F7HB37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

47917:WN53 RS21655
gene id: 47917:WN53_RS21655
uniprot id: A0A0F7HER0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

47917:WN53 RS24085
gene id: 47917:WN53_RS24085
uniprot id: A0A0F7HGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

47917:WN53 RS04685
gene id: 47917:WN53_RS04685
uniprot id: A0A0F7H8T8
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

47917:WN53 RS19615
gene id: 47917:WN53_RS19615
uniprot id: A0A0F7HDW1
names: Similarity
messages: Belongs to the glutamine synthetase family.

47917:WN53 RS15675
gene id: 47917:WN53_RS15675
uniprot id: A0A0F7D2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

47917:WN53 RS22585
gene id: 47917:WN53_RS22585
uniprot id: A0A0F7HGW0
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS09165
gene id: 47917:WN53_RS09165
uniprot id: A0A0F7D1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

47917:WN53 RS12050
gene id: 47917:WN53_RS12050
uniprot id: A0A0F7HBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

47917:WN53 RS06575
gene id: 47917:WN53_RS06575
uniprot id: A0A0F7H9I4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01340
gene id: 47917:WN53_RS01340
uniprot id: A0A0F7H7R3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS15810
gene id: 47917:WN53_RS15810
uniprot id: A0A0F7D2B7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

47917:WN53 RS12075
gene id: 47917:WN53_RS12075
uniprot id: A0A0F7HAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

47917:WN53 RS27245
gene id: 47917:WN53_RS27245
uniprot id: A0A1J7XPX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

47917:WN53 RS02380
gene id: 47917:WN53_RS02380
uniprot id: A0A0F7H7N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

47917:WN53 RS07845
gene id: 47917:WN53_RS07845
uniprot id: A0A0F7HAF1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

47917:WN53 RS00295
gene id: 47917:WN53_RS00295
uniprot id: A0A0F7H7A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

47917:WN53 RS00885
gene id: 47917:WN53_RS00885
uniprot id: A0A0F7H626
names: Similarity
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.

47917:WN53 RS01460
gene id: 47917:WN53_RS01460
uniprot id: A0A0F7H7H1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

47917:WN53 RS12765
gene id: 47917:WN53_RS12765
uniprot id: A0A0F7HAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS07825
gene id: 47917:WN53_RS07825
uniprot id: A0A0F7H8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

47917:WN53 RS15880
gene id: 47917:WN53_RS15880
uniprot id: A0A0F7HD03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

47917:WN53 RS23965
gene id: 47917:WN53_RS23965
uniprot id: A0A0F7HF64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

47917:WN53 RS09210
gene id: 47917:WN53_RS09210
uniprot id: A0A0F7HAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

47917:WN53 RS13740
gene id: 47917:WN53_RS13740
uniprot id: A0A0F7HC95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.

47917:WN53 RS17765
gene id: 47917:WN53_RS17765
uniprot id: A0A0F7HDP1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

47917:WN53 RS07440
gene id: 47917:WN53_RS07440
uniprot id: A0A0F7H8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

47917:WN53 RS17070
gene id: 47917:WN53_RS17070
uniprot id: A0A0F7HEJ3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25375
gene id: 47917:WN53_RS25375
uniprot id: A0A0F7HFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS16240
gene id: 47917:WN53_RS16240
uniprot id: A0A0F7HEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

47917:WN53 RS05420
gene id: 47917:WN53_RS05420
uniprot id: A0A0F7D198
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

47917:WN53 RS01590
gene id: 47917:WN53_RS01590
uniprot id: A0A0F7H7U9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

47917:WN53 RS02890
gene id: 47917:WN53_RS02890
uniprot id: A0A0F7H6X0
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

47917:WN53 RS19340
gene id: 47917:WN53_RS19340
uniprot id: A0A0F7HET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS07745
gene id: 47917:WN53_RS07745
uniprot id: A0A0F7HAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

47917:WN53 RS02430
gene id: 47917:WN53_RS02430
uniprot id: A0A0F7H701
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

47917:WN53 RS09340
gene id: 47917:WN53_RS09340
uniprot id: A0A0F7HB22
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

47917:WN53 RS02135
gene id: 47917:WN53_RS02135
uniprot id: A0A0F7D0Y3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

47917:WN53 RS09730
gene id: 47917:WN53_RS09730
uniprot id: A0A0F7HAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

47917:WN53 RS24140
gene id: 47917:WN53_RS24140
uniprot id: A0A0F7D369
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

47917:WN53 RS23920
gene id: 47917:WN53_RS23920
uniprot id: A0A0F7D361
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

47917:WN53 RS05285
gene id: 47917:WN53_RS05285
uniprot id: A0A0F7H853
names: Similarity
messages: Belongs to the CTP synthase family.

47917:WN53 RS10165
gene id: 47917:WN53_RS10165
uniprot id: A0A0F7HBD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

47917:WN53 RS00790
gene id: 47917:WN53_RS00790
uniprot id: A0A0F7H789
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

47917:WN53 RS03970
gene id: 47917:WN53_RS03970
uniprot id: A0A0F7H7H3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24265
gene id: 47917:WN53_RS24265
uniprot id: A0A0F7HGT0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS16465
gene id: 47917:WN53_RS16465
uniprot id: A0A0F7HED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS12585
gene id: 47917:WN53_RS12585
uniprot id: A0A0F7HBZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

47917:WN53 RS13585
gene id: 47917:WN53_RS13585
uniprot id: A0A0F7D235
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

47917:WN53 RS09385
gene id: 47917:WN53_RS09385
uniprot id: A0A0F7H9H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

47917:WN53 RS04930
gene id: 47917:WN53_RS04930
uniprot id: A0A0F7H8V7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS24055
gene id: 47917:WN53_RS24055
uniprot id: A0A0F7D366
names: Similarity
messages: Belongs to the MotB family.

47917:WN53 RS25480
gene id: 47917:WN53_RS25480
uniprot id: A0A0F7HI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS11795
gene id: 47917:WN53_RS11795
uniprot id: A0A0F7HBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

47917:WN53 RS19310
gene id: 47917:WN53_RS19310
uniprot id: A0A0F7HET1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

47917:WN53 RS17350
gene id: 47917:WN53_RS17350
uniprot id: A0A0F7HDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

47917:WN53 RS11350
gene id: 47917:WN53_RS11350
uniprot id: A0A0F7HAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

47917:WN53 RS20670
gene id: 47917:WN53_RS20670
uniprot id: A0A0F7HFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS21740
gene id: 47917:WN53_RS21740
uniprot id: A0A0F7HGK0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

47917:WN53 RS16970
gene id: 47917:WN53_RS16970
uniprot id: A0A0F7D2G0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

47917:WN53 RS09960
gene id: 47917:WN53_RS09960
uniprot id: A0A0F7HIK9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

47917:WN53 RS19240
gene id: 47917:WN53_RS19240
uniprot id: A0A0F7HES3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

47917:WN53 RS13710
gene id: 47917:WN53_RS13710
uniprot id: A0A0F7HD25
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

47917:WN53 RS18080
gene id: 47917:WN53_RS18080
uniprot id: A0A0F7HD98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

47917:WN53 RS04150
gene id: 47917:WN53_RS04150
uniprot id: A0A0F7H7L5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

47917:WN53 RS01700
gene id: 47917:WN53_RS01700
uniprot id: A0A0F7H6E9
names: Similarity
messages: Belongs to the skp family.

47917:WN53 RS04625
gene id: 47917:WN53_RS04625
uniprot id: A0A0F7H8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

47917:WN53 RS04660
gene id: 47917:WN53_RS04660
uniprot id: A0A0F7H8N6
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

47917:WN53 RS15710
gene id: 47917:WN53_RS15710
uniprot id: A0A0F7HIN9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

47917:WN53 RS10280
gene id: 47917:WN53_RS10280
uniprot id: A0A0F7HBF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

47917:WN53 RS01375
gene id: 47917:WN53_RS01375
uniprot id: A0A0F7H7R6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

47917:WN53 RS11080
gene id: 47917:WN53_RS11080
uniprot id: A0A0F7HB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS00135
gene id: 47917:WN53_RS00135
uniprot id: A0A0F7H6R8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS10805
gene id: 47917:WN53_RS10805
uniprot id: A0A0F7HBL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS10610
gene id: 47917:WN53_RS10610
uniprot id: A0A0F7HBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

47917:WN53 RS19930
gene id: 47917:WN53_RS19930
uniprot id: A0A0F7HEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

47917:WN53 RS14555
gene id: 47917:WN53_RS14555
uniprot id: A0A0F7HBN5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

47917:WN53 RS23440
gene id: 47917:WN53_RS23440
uniprot id: A0A0F7HH21
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS25785
gene id: 47917:WN53_RS25785
uniprot id: A0A0F7HHD3
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

47917:WN53 RS23880
gene id: 47917:WN53_RS23880
uniprot id: A0A0F7HGG3
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

47917:WN53 RS17345
gene id: 47917:WN53_RS17345
uniprot id: A0A0F7HDW2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

47917:WN53 RS17835
gene id: 47917:WN53_RS17835
uniprot id: A0A0F7HDP8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

47917:WN53 RS05295
gene id: 47917:WN53_RS05295
uniprot id: A0A0F7D193
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS17630
gene id: 47917:WN53_RS17630
uniprot id: A0A0F7HE01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

47917:WN53 RS09170
gene id: 47917:WN53_RS09170
uniprot id: A0A0F7H9E7
names: Similarity
messages: Belongs to the peptidase M16 family.

47917:WN53 RS20175
gene id: 47917:WN53_RS20175
uniprot id: A0A0F7D2S7
names: Similarity
messages: Belongs to the peptidase C40 family.

47917:WN53 RS13545
gene id: 47917:WN53_RS13545
uniprot id: A0A0F7HC67
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

47917:WN53 RS09690
gene id: 47917:WN53_RS09690
uniprot id: A0A0F7HAI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS10315
gene id: 47917:WN53_RS10315
uniprot id: A0A0F7HA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

47917:WN53 RS08360
gene id: 47917:WN53_RS08360
uniprot id: A0A0F7HA61
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

47917:WN53 RS25040
gene id: 47917:WN53_RS25040
uniprot id: A0A0F7D3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

47917:WN53 RS22280
gene id: 47917:WN53_RS22280
uniprot id: A0A0F7HEN8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

47917:WN53 RS15780
gene id: 47917:WN53_RS15780
uniprot id: A0A0F7HCZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

47917:WN53 RS25900
gene id: 47917:WN53_RS25900
uniprot id: A0A0F7HI86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

47917:WN53 RS05600
gene id: 47917:WN53_RS05600
uniprot id: A0A0F7H9G5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

47917:WN53 RS06360
gene id: 47917:WN53_RS06360
uniprot id: A0A0F7H8J3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

47917:WN53 RS06040
gene id: 47917:WN53_RS06040
uniprot id: A0A0F7D1C1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS22725
gene id: 47917:WN53_RS22725
uniprot id: A0A0F7HGX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

47917:WN53 RS06060
gene id: 47917:WN53_RS06060
uniprot id: A0A0F7H9B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

47917:WN53 RS25520
gene id: 47917:WN53_RS25520
uniprot id: A0A0F7HFS2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

47917:WN53 RS10835
gene id: 47917:WN53_RS10835
uniprot id: A0A0F7HBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

47917:WN53 RS10575
gene id: 47917:WN53_RS10575
uniprot id: A0A0F7HA42
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

47917:WN53 RS01450
gene id: 47917:WN53_RS01450
uniprot id: A0A0F7D0V9
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP).

47917:WN53 RS03235
gene id: 47917:WN53_RS03235
uniprot id: A0A0F7D121
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

47917:WN53 RS02305
gene id: 47917:WN53_RS02305
uniprot id: A0A0F7D0Y8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

47917:WN53 RS02040
gene id: 47917:WN53_RS02040
uniprot id: A0A0F7H7Q6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07275
gene id: 47917:WN53_RS07275
uniprot id: A0A0F7HA64
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

47917:WN53 RS17565
gene id: 47917:WN53_RS17565
uniprot id: A0A0F7D2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

47917:WN53 RS03265
gene id: 47917:WN53_RS03265
uniprot id: A0A0F7D3G7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

47917:WN53 RS16430
gene id: 47917:WN53_RS16430
uniprot id: A0A0F7HED1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

47917:WN53 RS06185
gene id: 47917:WN53_RS06185
uniprot id: A0A0F7D3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS00500
gene id: 47917:WN53_RS00500
uniprot id: A0A0F7HHN4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS19300
gene id: 47917:WN53_RS19300
uniprot id: A0A0F7HDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

47917:WN53 RS17710
gene id: 47917:WN53_RS17710
uniprot id: A0A0F7HEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

47917:WN53 RS08365
gene id: 47917:WN53_RS08365
uniprot id: A0A0F7HAR0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

47917:WN53 RS03015
gene id: 47917:WN53_RS03015
uniprot id: A0A0F7H6Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

47917:WN53 RS13430
gene id: 47917:WN53_RS13430
uniprot id: A0A0F7HCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS15985
gene id: 47917:WN53_RS15985
uniprot id: A0A0F7HCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS23405
gene id: 47917:WN53_RS23405
uniprot id: A0A0F7HGC9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

47917:WN53 RS17190
gene id: 47917:WN53_RS17190
uniprot id: A0A0F7HDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS23220
gene id: 47917:WN53_RS23220
uniprot id: A0A0F7HI21
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

47917:WN53 RS15305
gene id: 47917:WN53_RS15305
uniprot id: A0A0F7HBV8
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

47917:WN53 RS11605
gene id: 47917:WN53_RS11605
uniprot id: A0A0F7HBP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

47917:WN53 RS09260
gene id: 47917:WN53_RS09260
uniprot id: A0A0F7H9N5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

47917:WN53 RS05245
gene id: 47917:WN53_RS05245
uniprot id: A0A0F7H9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

47917:WN53 RS09785
gene id: 47917:WN53_RS09785
uniprot id: A0A0F7HAY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

47917:WN53 RS24100
gene id: 47917:WN53_RS24100
uniprot id: A0A0F7HIC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

47917:WN53 RS24175
gene id: 47917:WN53_RS24175
uniprot id: A0A0F7HFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

47917:WN53 RS16245
gene id: 47917:WN53_RS16245
uniprot id: A0A0F7HCE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

47917:WN53 RS06410
gene id: 47917:WN53_RS06410
uniprot id: A0A0F7H9A9
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

47917:WN53 RS01765
gene id: 47917:WN53_RS01765
uniprot id: A0A0F7H6F9
names: Similarity
messages: Belongs to the UPF0325 family.

47917:WN53 RS06905
gene id: 47917:WN53_RS06905
uniprot id: A0A0F7H8G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

47917:WN53 RS23995
gene id: 47917:WN53_RS23995
uniprot id: A0A0F7HF69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS14520
gene id: 47917:WN53_RS14520
uniprot id: A0A0F7D270
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

47917:WN53 RS11910
gene id: 47917:WN53_RS11910
uniprot id: A0A0F7HAP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

47917:WN53 RS25605
gene id: 47917:WN53_RS25605
uniprot id: A0A0F7HH89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

47917:WN53 RS13570
gene id: 47917:WN53_RS13570
uniprot id: A0A0F7HCC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

47917:WN53 RS10085
gene id: 47917:WN53_RS10085
uniprot id: A0A0F7HAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorD/DmsD family. TorD subfamily.
messages: Cytoplasm
messages: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

47917:WN53 RS11060
gene id: 47917:WN53_RS11060
uniprot id: A0A0F7HA32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

47917:WN53 RS15995
gene id: 47917:WN53_RS15995
uniprot id: A0A0F7D2C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

47917:WN53 RS21070
gene id: 47917:WN53_RS21070
uniprot id: A0A0F7HED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

47917:WN53 RS00660
gene id: 47917:WN53_RS00660
uniprot id: A0A0F7H769
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

47917:WN53 RS11085
gene id: 47917:WN53_RS11085
uniprot id: A0A0F7HBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS18890
gene id: 47917:WN53_RS18890
uniprot id: A0A0F7HEK3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

47917:WN53 RS10520
gene id: 47917:WN53_RS10520
uniprot id: A0A0F7H9X7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

47917:WN53 RS07330
gene id: 47917:WN53_RS07330
uniprot id: A0A0F7H9T4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

47917:WN53 RS10850
gene id: 47917:WN53_RS10850
uniprot id: A0A0F7HA12
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05455
gene id: 47917:WN53_RS05455
uniprot id: A0A0F7H920
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

47917:WN53 RS15620
gene id: 47917:WN53_RS15620
uniprot id: A0A0F7D2B0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS00550
gene id: 47917:WN53_RS00550
uniprot id: A0A0F7H700
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

47917:WN53 RS06150
gene id: 47917:WN53_RS06150
uniprot id: A0A0F7H8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS15515
gene id: 47917:WN53_RS15515
uniprot id: A0A0F7D2A6
names: Similarity
messages: Belongs to the asparagine synthetase family.

47917:WN53 RS21415
gene id: 47917:WN53_RS21415
uniprot id: A0A0F7HGB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04510
gene id: 47917:WN53_RS04510
uniprot id: A0A0F7H7V1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

47917:WN53 RS03245
gene id: 47917:WN53_RS03245
uniprot id: A0A0F7H7A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

47917:WN53 RS14970
gene id: 47917:WN53_RS14970
uniprot id: A0A0F7HBS5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23925
gene id: 47917:WN53_RS23925
uniprot id: A0A0F7HH53
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

47917:WN53 RS25920
gene id: 47917:WN53_RS25920
uniprot id: A0A0F7D3D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS17045
gene id: 47917:WN53_RS17045
uniprot id: A0A0F7HCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

47917:WN53 RS17680
gene id: 47917:WN53_RS17680
uniprot id: A0A0F7HCW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

47917:WN53 RS25875
gene id: 47917:WN53_RS25875
uniprot id: A0A0F7HFX9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS10740
gene id: 47917:WN53_RS10740
uniprot id: A0A0F7HBK4
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

47917:WN53 RS25940
gene id: 47917:WN53_RS25940
uniprot id: A0A0F7HGH2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS14445
gene id: 47917:WN53_RS14445
uniprot id: A0A0F7D267
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS00020
gene id: 47917:WN53_RS00020
uniprot id: A0A0F7H5L9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS16845
gene id: 47917:WN53_RS16845
uniprot id: A0A0F7HCP8
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS22740
gene id: 47917:WN53_RS22740
uniprot id: A0A0F7HGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

47917:WN53 RS19210
gene id: 47917:WN53_RS19210
uniprot id: A0A0F7D2P2
names: Similarity
messages: Belongs to the fabD family.

47917:WN53 RS01945
gene id: 47917:WN53_RS01945
uniprot id: A0A0F7H7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

47917:WN53 RS20155
gene id: 47917:WN53_RS20155
uniprot id: A0A0F7HFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS18480
gene id: 47917:WN53_RS18480
uniprot id: A0A0F7HEE6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

47917:WN53 RS08105
gene id: 47917:WN53_RS08105
uniprot id: A0A0F7D1J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

47917:WN53 RS12595
gene id: 47917:WN53_RS12595
uniprot id: A0A0F7HBV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS12345
gene id: 47917:WN53_RS12345
uniprot id: A0A0F7D1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

47917:WN53 RS24030
gene id: 47917:WN53_RS24030
uniprot id: A0A0F7D365
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

47917:WN53 RS25870
gene id: 47917:WN53_RS25870
uniprot id: A0A0F7D3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

47917:WN53 RS02345
gene id: 47917:WN53_RS02345
uniprot id: A0A0F7H7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

47917:WN53 RS04670
gene id: 47917:WN53_RS04670
uniprot id: A0A0F7D170
names: Similarity
messages: Belongs to the glutamate synthase family.

47917:WN53 RS22525
gene id: 47917:WN53_RS22525
uniprot id: A0A0F7HHI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

47917:WN53 RS24990
gene id: 47917:WN53_RS24990
uniprot id: A0A0F7HG19
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07545
gene id: 47917:WN53_RS07545
uniprot id: A0A0F7D1H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS22900
gene id: 47917:WN53_RS22900
uniprot id: A0A0F7HG70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

47917:WN53 RS17500
gene id: 47917:WN53_RS17500
uniprot id: A0A8H9YGG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

47917:WN53 RS09605
gene id: 47917:WN53_RS09605
uniprot id: A0A0F7D1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS04245
gene id: 47917:WN53_RS04245
uniprot id: A0A0F7D154
names: Similarity
messages: Belongs to the archaeal-type GPI family.

47917:WN53 RS23805
gene id: 47917:WN53_RS23805
uniprot id: A0A0F7HGF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

47917:WN53 RS16260
gene id: 47917:WN53_RS16260
uniprot id: A0A0F7HDE3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

47917:WN53 RS25580
gene id: 47917:WN53_RS25580
uniprot id: A0A0F7HHB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

47917:WN53 RS00710
gene id: 47917:WN53_RS00710
uniprot id: A0A0F7H7I3
names: Similarity
messages: Belongs to the YfgM family.

47917:WN53 RS17770
gene id: 47917:WN53_RS17770
uniprot id: A0A0F7D2J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

47917:WN53 RS07785
gene id: 47917:WN53_RS07785
uniprot id: A0A0F7D1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

47917:WN53 RS04100
gene id: 47917:WN53_RS04100
uniprot id: A0A0F7H8H9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

47917:WN53 RS26410
gene id: 47917:WN53_RS26410
uniprot id: A0A0F7HG42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

47917:WN53 RS25845
gene id: 47917:WN53_RS25845
uniprot id: A0A0F7HGG0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

47917:WN53 RS09955
gene id: 47917:WN53_RS09955
uniprot id: A0A0F7HB13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

47917:WN53 RS25155
gene id: 47917:WN53_RS25155
uniprot id: A0A0F7HG88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

47917:WN53 RS19960
gene id: 47917:WN53_RS19960
uniprot id: A0A0F7HF40
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

47917:WN53 RS10235
gene id: 47917:WN53_RS10235
uniprot id: A0A0F7HBE5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

47917:WN53 RS15605
gene id: 47917:WN53_RS15605
uniprot id: A0A0F7HD52
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

47917:WN53 RS07790
gene id: 47917:WN53_RS07790
uniprot id: A0A0F7H8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

47917:WN53 RS08680
gene id: 47917:WN53_RS08680
uniprot id: A0A0F7HAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS02690
gene id: 47917:WN53_RS02690
uniprot id: A0A0F7H801
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS18450
gene id: 47917:WN53_RS18450
uniprot id: A0A0F7HEE3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00300
gene id: 47917:WN53_RS00300
uniprot id: A0A0F7H606
names: Similarity
messages: Belongs to the ArsC family.

47917:WN53 RS05450
gene id: 47917:WN53_RS05450
uniprot id: A0A0F7H7W0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

47917:WN53 RS10845
gene id: 47917:WN53_RS10845
uniprot id: A0A0F7D1T9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS24985
gene id: 47917:WN53_RS24985
uniprot id: A0A0F7D399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS00055
gene id: 47917:WN53_RS00055
uniprot id: A0A0F7H5M4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05850
gene id: 47917:WN53_RS05850
uniprot id: A0A0F7H926
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

47917:WN53 RS04095
gene id: 47917:WN53_RS04095
uniprot id: A0A0F7D148
names: Subunit
messages: Monomer.

47917:WN53 RS12140
gene id: 47917:WN53_RS12140
uniprot id: A0A0F7HBV0
names: Similarity
messages: Belongs to the GSP E family.

47917:WN53 RS16750
gene id: 47917:WN53_RS16750
uniprot id: A0A0F7HCE5
names: Subcellular Location Annotation
messages: Cell outer membrane

47917:WN53 RS27255
gene id: 47917:WN53_RS27255
uniprot id: A0A4P8U9L2
names: Caution
names: Function
names: Similarity
messages: Belongs to the thr operon leader peptide family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein is involved in control of the biosynthesis of threonine.

47917:WN53 RS25715
gene id: 47917:WN53_RS25715
uniprot id: A0A0F7HHA1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07310
gene id: 47917:WN53_RS07310
uniprot id: A0A0F7H8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

47917:WN53 RS16330
gene id: 47917:WN53_RS16330
uniprot id: A0A0F7D2D6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS27650
gene id: 47917:WN53_RS27650
uniprot id: A0A1Q5VBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

47917:WN53 RS12325
gene id: 47917:WN53_RS12325
uniprot id: A0A0F7HBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

47917:WN53 RS09200
gene id: 47917:WN53_RS09200
uniprot id: A0A0F7H9F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

47917:WN53 RS16645
gene id: 47917:WN53_RS16645
uniprot id: A0A0F7HDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS02100
gene id: 47917:WN53_RS02100
uniprot id: A0A0F7H6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS17755
gene id: 47917:WN53_RS17755
uniprot id: A0A0F7HD28
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS25910
gene id: 47917:WN53_RS25910
uniprot id: A0A0F7HGG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS20205
gene id: 47917:WN53_RS20205
uniprot id: A0A0F7HF68
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS07240
gene id: 47917:WN53_RS07240
uniprot id: A0A0F7HA60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS02665
gene id: 47917:WN53_RS02665
uniprot id: A0A0F7H7R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

47917:WN53 RS10680
gene id: 47917:WN53_RS10680
uniprot id: A0A0F7HA53
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

47917:WN53 RS08685
gene id: 47917:WN53_RS08685
uniprot id: A0A0F7HAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS06180
gene id: 47917:WN53_RS06180
uniprot id: A0A0F7H8H0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS19030
gene id: 47917:WN53_RS19030
uniprot id: A0A0F7HI52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

47917:WN53 RS22975
gene id: 47917:WN53_RS22975
uniprot id: A0A0F7HG76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

47917:WN53 RS00555
gene id: 47917:WN53_RS00555
uniprot id: A0A0F7D0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

47917:WN53 RS10175
gene id: 47917:WN53_RS10175
uniprot id: A0A0F7H9Z8
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

47917:WN53 RS05160
gene id: 47917:WN53_RS05160
uniprot id: A0A0F7D188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

47917:WN53 RS23685
gene id: 47917:WN53_RS23685
uniprot id: A0A0F7HF30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS05620
gene id: 47917:WN53_RS05620
uniprot id: A0A0F7H946
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

47917:WN53 RS22260
gene id: 47917:WN53_RS22260
uniprot id: A0A0F7D303
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

47917:WN53 RS16690
gene id: 47917:WN53_RS16690
uniprot id: A0A0F7HDC7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

47917:WN53 RS06580
gene id: 47917:WN53_RS06580
uniprot id: A0A0F7H9H1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

47917:WN53 RS22665
gene id: 47917:WN53_RS22665
uniprot id: A0A0F7HGW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

47917:WN53 RS01895
gene id: 47917:WN53_RS01895
uniprot id: A0A0F7H6H2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

47917:WN53 RS09590
gene id: 47917:WN53_RS09590
uniprot id: A0A0F7HAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

47917:WN53 RS14215
gene id: 47917:WN53_RS14215
uniprot id: A0A0F7D258
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

47917:WN53 RS19435
gene id: 47917:WN53_RS19435
uniprot id: A0A0F7HDU2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS18825
gene id: 47917:WN53_RS18825
uniprot id: A0A0F7HE90
names: Similarity
messages: Belongs to the HupF/HypC family.

47917:WN53 RS23455
gene id: 47917:WN53_RS23455
uniprot id: A0A0F7HFD0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25285
gene id: 47917:WN53_RS25285
uniprot id: A0A0F7HH58
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

47917:WN53 RS19350
gene id: 47917:WN53_RS19350
uniprot id: A0A0F7HEI0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

47917:WN53 RS14305
gene id: 47917:WN53_RS14305
uniprot id: A0A0F7HBG8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

47917:WN53 RS16535
gene id: 47917:WN53_RS16535
uniprot id: A0A0F7HCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS20520
gene id: 47917:WN53_RS20520
uniprot id: A0A0F7HIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

47917:WN53 RS02885
gene id: 47917:WN53_RS02885
uniprot id: A0A0F7D109
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

47917:WN53 RS11050
gene id: 47917:WN53_RS11050
uniprot id: A0A0F7HBN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

47917:WN53 RS05440
gene id: 47917:WN53_RS05440
uniprot id: A0A0F7H874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

47917:WN53 RS18820
gene id: 47917:WN53_RS18820
uniprot id: A0A0F7HEG6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

47917:WN53 RS02830
gene id: 47917:WN53_RS02830
uniprot id: A0A0F7H821
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS15110
gene id: 47917:WN53_RS15110
uniprot id: A0A0F7HBT5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

47917:WN53 RS00195
gene id: 47917:WN53_RS00195
uniprot id: A0A0F7D0R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

47917:WN53 RS24245
gene id: 47917:WN53_RS24245
uniprot id: A0A0F7HF96
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

47917:WN53 RS06015
gene id: 47917:WN53_RS06015
uniprot id: A0A0F7D1C0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

47917:WN53 RS11965
gene id: 47917:WN53_RS11965
uniprot id: A0A0F7HCA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

47917:WN53 RS06100
gene id: 47917:WN53_RS06100
uniprot id: A0A0F7H965
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

47917:WN53 RS18090
gene id: 47917:WN53_RS18090
uniprot id: A0A0F7HEA4
names: Similarity
messages: Belongs to the acylphosphatase family.

47917:WN53 RS17705
gene id: 47917:WN53_RS17705
uniprot id: A0A0F7HI41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

47917:WN53 RS14295
gene id: 47917:WN53_RS14295
uniprot id: A0A0F7HDD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

47917:WN53 RS12505
gene id: 47917:WN53_RS12505
uniprot id: A0A0F7D1Z9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

47917:WN53 RS06940
gene id: 47917:WN53_RS06940
uniprot id: A0A0F7D1F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS08260
gene id: 47917:WN53_RS08260
uniprot id: A0A0F7HAP4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS13055
gene id: 47917:WN53_RS13055
uniprot id: A0A0F7D217
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

47917:WN53 RS05760
gene id: 47917:WN53_RS05760
uniprot id: A0A0F7H9I5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

47917:WN53 RS02980
gene id: 47917:WN53_RS02980
uniprot id: A0A0F7H6Y0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

47917:WN53 RS05030
gene id: 47917:WN53_RS05030
uniprot id: A0A0F7H8W9
names: Similarity
messages: Belongs to the CFA/CMAS family.

47917:WN53 RS06820
gene id: 47917:WN53_RS06820
uniprot id: A0A0F7H9K9
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

47917:WN53 RS19820
gene id: 47917:WN53_RS19820
uniprot id: A0A0F7HF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS17145
gene id: 47917:WN53_RS17145
uniprot id: A0A0F7HCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS11500
gene id: 47917:WN53_RS11500
uniprot id: A0A0F7HC00
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS19250
gene id: 47917:WN53_RS19250
uniprot id: A0A0F7HFK0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

47917:WN53 RS13800
gene id: 47917:WN53_RS13800
uniprot id: A0A0F7HB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
messages: Membrane

47917:WN53 RS16935
gene id: 47917:WN53_RS16935
uniprot id: A0A0F7HEI4
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

47917:WN53 RS17650
gene id: 47917:WN53_RS17650
uniprot id: A0A0F7HCW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS11870
gene id: 47917:WN53_RS11870
uniprot id: A0A0F7D1X6
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

47917:WN53 RS14580
gene id: 47917:WN53_RS14580
uniprot id: A0A0F7HDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

47917:WN53 RS04200
gene id: 47917:WN53_RS04200
uniprot id: A0A0F7H8G9
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

47917:WN53 RS12055
gene id: 47917:WN53_RS12055
uniprot id: A0A0F7HBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

47917:WN53 RS27840
gene id: 47917:WN53_RS27840
uniprot id: A0A0F7H8B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

47917:WN53 RS00935
gene id: 47917:WN53_RS00935
uniprot id: A0A0F7HHR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

47917:WN53 RS12550
gene id: 47917:WN53_RS12550
uniprot id: A0A0F7HAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS23070
gene id: 47917:WN53_RS23070
uniprot id: A0A0F7HH04
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS18895
gene id: 47917:WN53_RS18895
uniprot id: A0A0F7HE98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

47917:WN53 RS10560
gene id: 47917:WN53_RS10560
uniprot id: A0A0F7HB85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

47917:WN53 RS01815
gene id: 47917:WN53_RS01815
uniprot id: A0A0F7H7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

47917:WN53 RS23370
gene id: 47917:WN53_RS23370
uniprot id: A0A0F7HGC6
names: Similarity
messages: Belongs to the UPF0181 family.

47917:WN53 RS14310
gene id: 47917:WN53_RS14310
uniprot id: A0A0F7HCJ2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

47917:WN53 RS15615
gene id: 47917:WN53_RS15615
uniprot id: A0A0F7HE06
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

47917:WN53 RS02465
gene id: 47917:WN53_RS02465
uniprot id: A0A0F7H705
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

47917:WN53 RS22840
gene id: 47917:WN53_RS22840
uniprot id: A0A0F7HG72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS25440
gene id: 47917:WN53_RS25440
uniprot id: A0A0F7HHA6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

47917:WN53 RS24060
gene id: 47917:WN53_RS24060
uniprot id: A0A0F7HHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

47917:WN53 RS24005
gene id: 47917:WN53_RS24005
uniprot id: A0A0F7HFL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

47917:WN53 RS06365
gene id: 47917:WN53_RS06365
uniprot id: A0A0F7H898
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

47917:WN53 RS09950
gene id: 47917:WN53_RS09950
uniprot id: A0A0F7H9Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

47917:WN53 RS15405
gene id: 47917:WN53_RS15405
uniprot id: A0A0F7D2A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

47917:WN53 RS17665
gene id: 47917:WN53_RS17665
uniprot id: A0A0F7D2I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

47917:WN53 RS24345
gene id: 47917:WN53_RS24345
uniprot id: A0A0F7HFQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

47917:WN53 RS14515
gene id: 47917:WN53_RS14515
uniprot id: A0A0F7HDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

47917:WN53 RS04015
gene id: 47917:WN53_RS04015
uniprot id: A0A0F7H777
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04535
gene id: 47917:WN53_RS04535
uniprot id: A0A0F7H917
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS07700
gene id: 47917:WN53_RS07700
uniprot id: A0A0F7HA03
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

47917:WN53 RS09660
gene id: 47917:WN53_RS09660
uniprot id: A0A0F7HAH7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS04805
gene id: 47917:WN53_RS04805
uniprot id: A0A0F7H8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

47917:WN53 RS06385
gene id: 47917:WN53_RS06385
uniprot id: A0A0F7H9S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

47917:WN53 RS11845
gene id: 47917:WN53_RS11845
uniprot id: A0A0F7D1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with the regulatory subunit KefF.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

47917:WN53 RS00985
gene id: 47917:WN53_RS00985
uniprot id: A0A0F7H6E7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

47917:WN53 RS11815
gene id: 47917:WN53_RS11815
uniprot id: A0A0F7HIL4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

47917:WN53 RS03250
gene id: 47917:WN53_RS03250
uniprot id: A0A0F7H6Z7
names: Function
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

47917:WN53 RS15345
gene id: 47917:WN53_RS15345
uniprot id: A0A0F7HCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

47917:WN53 RS07420
gene id: 47917:WN53_RS07420
uniprot id: A0A0F7H9X0
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

47917:WN53 RS18780
gene id: 47917:WN53_RS18780
uniprot id: A0A0F7HDI2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

47917:WN53 RS02815
gene id: 47917:WN53_RS02815
uniprot id: A0A0F7H8C3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

47917:WN53 RS10075
gene id: 47917:WN53_RS10075
uniprot id: A0A0F7H9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: Cytoplasm
messages: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.

47917:WN53 RS12085
gene id: 47917:WN53_RS12085
uniprot id: A0A0F7HBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

47917:WN53 RS22370
gene id: 47917:WN53_RS22370
uniprot id: A0A0F7D307
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

47917:WN53 RS05845
gene id: 47917:WN53_RS05845
uniprot id: A0A0F7H979
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

47917:WN53 RS02445
gene id: 47917:WN53_RS02445
uniprot id: A0A0F7D0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

47917:WN53 RS03240
gene id: 47917:WN53_RS03240
uniprot id: A0A0F7H8H7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

47917:WN53 RS22080
gene id: 47917:WN53_RS22080
uniprot id: A0A0F7HGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

47917:WN53 RS24555
gene id: 47917:WN53_RS24555
uniprot id: A0A0F7HFD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

47917:WN53 RS05855
gene id: 47917:WN53_RS05855
uniprot id: A0A0F7H9K1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

47917:WN53 RS07050
gene id: 47917:WN53_RS07050
uniprot id: A0A0F7HA33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

47917:WN53 RS17860
gene id: 47917:WN53_RS17860
uniprot id: A0A0F7HE29
names: Similarity
messages: Belongs to the UPF0434 family.

47917:WN53 RS04790
gene id: 47917:WN53_RS04790
uniprot id: A0A0F7D174
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS18715
gene id: 47917:WN53_RS18715
uniprot id: A0A0F7HEF8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

47917:WN53 RS22445
gene id: 47917:WN53_RS22445
uniprot id: A0A0F7HGU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

47917:WN53 RS19940
gene id: 47917:WN53_RS19940
uniprot id: A0A0F7HDR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

47917:WN53 RS14715
gene id: 47917:WN53_RS14715
uniprot id: A0A0F7HBS8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS03035
gene id: 47917:WN53_RS03035
uniprot id: A0A0F7D115
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

47917:WN53 RS19470
gene id: 47917:WN53_RS19470
uniprot id: A0A0F7D3K4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

47917:WN53 RS17480
gene id: 47917:WN53_RS17480
uniprot id: A0A0F7HEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

47917:WN53 RS10405
gene id: 47917:WN53_RS10405
uniprot id: A0A0F7HBG7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

47917:WN53 RS10445
gene id: 47917:WN53_RS10445
uniprot id: A0A0F7D1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS20600
gene id: 47917:WN53_RS20600
uniprot id: A0A0F7HF32
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22735
gene id: 47917:WN53_RS22735
uniprot id: A0A0F7HET0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS13745
gene id: 47917:WN53_RS13745
uniprot id: A0A0F7D241
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25485
gene id: 47917:WN53_RS25485
uniprot id: A0A0F7D3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS09545
gene id: 47917:WN53_RS09545
uniprot id: A0A0F7H9S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

47917:WN53 RS03750
gene id: 47917:WN53_RS03750
uniprot id: A0A0F7H8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS19920
gene id: 47917:WN53_RS19920
uniprot id: A0A0F7D2R8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

47917:WN53 RS13910
gene id: 47917:WN53_RS13910
uniprot id: A0A0F7HB91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

47917:WN53 RS15570
gene id: 47917:WN53_RS15570
uniprot id: A0A0F7HD50
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS02555
gene id: 47917:WN53_RS02555
uniprot id: A0A0F7H6R9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

47917:WN53 RS21355
gene id: 47917:WN53_RS21355
uniprot id: A0A0F7HEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

47917:WN53 RS12340
gene id: 47917:WN53_RS12340
uniprot id: A0A0F7HAV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

47917:WN53 RS06880
gene id: 47917:WN53_RS06880
uniprot id: A0A0F7H9M7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

47917:WN53 RS20040
gene id: 47917:WN53_RS20040
uniprot id: A0A0F7HEV4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

47917:WN53 RS21595
gene id: 47917:WN53_RS21595
uniprot id: A0A0F7D2X8
names: Similarity
messages: Belongs to the FGGY kinase family.

47917:WN53 RS07805
gene id: 47917:WN53_RS07805
uniprot id: A0A0F7HAE9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS13525
gene id: 47917:WN53_RS13525
uniprot id: A0A0F7HBB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

47917:WN53 RS06345
gene id: 47917:WN53_RS06345
uniprot id: A0A0F7H999
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

47917:WN53 RS22300
gene id: 47917:WN53_RS22300
uniprot id: A0A0F7HF07
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

47917:WN53 RS25030
gene id: 47917:WN53_RS25030
uniprot id: A0A0F7HH00
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS21800
gene id: 47917:WN53_RS21800
uniprot id: A0A0F7D2Y6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

47917:WN53 RS26160
gene id: 47917:WN53_RS26160
uniprot id: A0A0F7HI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS05490
gene id: 47917:WN53_RS05490
uniprot id: A0A0F7H8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

47917:WN53 RS10550
gene id: 47917:WN53_RS10550
uniprot id: A0A0F7H9Y1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

47917:WN53 RS04085
gene id: 47917:WN53_RS04085
uniprot id: A0A0F7H7K5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

47917:WN53 RS05790
gene id: 47917:WN53_RS05790
uniprot id: A0A0F7D1B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS12570
gene id: 47917:WN53_RS12570
uniprot id: A0A0F7HCM3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

47917:WN53 RS23935
gene id: 47917:WN53_RS23935
uniprot id: A0A0F7HFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

47917:WN53 RS10285
gene id: 47917:WN53_RS10285
uniprot id: A0A0F7HA08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS00010
gene id: 47917:WN53_RS00010
uniprot id: A0A0F7H764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

47917:WN53 RS26565
gene id: 47917:WN53_RS26565
uniprot id: A0A0F7HGS4
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS25435
gene id: 47917:WN53_RS25435
uniprot id: A0A0F7HH71
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

47917:WN53 RS20740
gene id: 47917:WN53_RS20740
uniprot id: A0A0F7HFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

47917:WN53 RS23590
gene id: 47917:WN53_RS23590
uniprot id: A0A0F7HGW2
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

47917:WN53 RS15040
gene id: 47917:WN53_RS15040
uniprot id: A0A0F7D289
names: Similarity
messages: Belongs to the carbamate kinase family.

47917:WN53 RS00755
gene id: 47917:WN53_RS00755
uniprot id: A0A0F7D0T3
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

47917:WN53 RS01415
gene id: 47917:WN53_RS01415
uniprot id: A0A0F7H6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

47917:WN53 RS12115
gene id: 47917:WN53_RS12115
uniprot id: A0A0F7HBK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

47917:WN53 RS18290
gene id: 47917:WN53_RS18290
uniprot id: A0A0F7D3K1
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

47917:WN53 RS15470
gene id: 47917:WN53_RS15470
uniprot id: A0A0F7HD44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS10040
gene id: 47917:WN53_RS10040
uniprot id: A0A0F7D1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS21695
gene id: 47917:WN53_RS21695
uniprot id: A0A0F7D2Y2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS18020
gene id: 47917:WN53_RS18020
uniprot id: A0A0F7HE53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

47917:WN53 RS05315
gene id: 47917:WN53_RS05315
uniprot id: A0A0F7H858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

47917:WN53 RS00875
gene id: 47917:WN53_RS00875
uniprot id: A0A0F7H7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS01075
gene id: 47917:WN53_RS01075
uniprot id: A0A0F7D0U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS12060
gene id: 47917:WN53_RS12060
uniprot id: A0A0F7HCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

47917:WN53 RS01835
gene id: 47917:WN53_RS01835
uniprot id: A0A0F7H7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS09775
gene id: 47917:WN53_RS09775
uniprot id: A0A0F7H9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

47917:WN53 RS01045
gene id: 47917:WN53_RS01045
uniprot id: A0A0F7H6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

47917:WN53 RS22540
gene id: 47917:WN53_RS22540
uniprot id: A0A0F7HIA6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

47917:WN53 RS08970
gene id: 47917:WN53_RS08970
uniprot id: A0A0F7HAY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

47917:WN53 RS01565
gene id: 47917:WN53_RS01565
uniprot id: A0A0F7H6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

47917:WN53 RS21710
gene id: 47917:WN53_RS21710
uniprot id: A0A0F7HEI8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20570
gene id: 47917:WN53_RS20570
uniprot id: A0A0F7HG06
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

47917:WN53 RS12120
gene id: 47917:WN53_RS12120
uniprot id: A0A0F7D1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

47917:WN53 RS11055
gene id: 47917:WN53_RS11055
uniprot id: A0A0F7HA84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

47917:WN53 RS17730
gene id: 47917:WN53_RS17730
uniprot id: A0A0F7HE14
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

47917:WN53 RS12250
gene id: 47917:WN53_RS12250
uniprot id: A0A0F7HAP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04925
gene id: 47917:WN53_RS04925
uniprot id: A0A0F7H7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS09510
gene id: 47917:WN53_RS09510
uniprot id: A0A0F7HB43
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

47917:WN53 RS06420
gene id: 47917:WN53_RS06420
uniprot id: A0A0F7H9T5
names: Similarity
messages: Belongs to the pirin family.

47917:WN53 RS17425
gene id: 47917:WN53_RS17425
uniprot id: A0A0F7HCT9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

47917:WN53 RS06995
gene id: 47917:WN53_RS06995
uniprot id: A0A0F7H8R6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

47917:WN53 RS24330
gene id: 47917:WN53_RS24330
uniprot id: A0A0F7D376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS01950
gene id: 47917:WN53_RS01950
uniprot id: A0A0F7D0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

47917:WN53 RS15300
gene id: 47917:WN53_RS15300
uniprot id: A0A0F7D299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

47917:WN53 RS20110
gene id: 47917:WN53_RS20110
uniprot id: A0A0F7HFV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

47917:WN53 RS17210
gene id: 47917:WN53_RS17210
uniprot id: A0A0F7HCV2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14300
gene id: 47917:WN53_RS14300
uniprot id: A0A0F7HBJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

47917:WN53 RS07245
gene id: 47917:WN53_RS07245
uniprot id: A0A0F7D1G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

47917:WN53 RS22635
gene id: 47917:WN53_RS22635
uniprot id: A0A0F7HES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

47917:WN53 RS04755
gene id: 47917:WN53_RS04755
uniprot id: A0A0F7H7Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

47917:WN53 RS13125
gene id: 47917:WN53_RS13125
uniprot id: A0A0F7HC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

47917:WN53 RS14760
gene id: 47917:WN53_RS14760
uniprot id: A0A0F7HCT3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

47917:WN53 RS16995
gene id: 47917:WN53_RS16995
uniprot id: A0A0F7D2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS10860
gene id: 47917:WN53_RS10860
uniprot id: A0A0F7HAZ9
names: Similarity
messages: Belongs to the RutC family.

47917:WN53 RS13560
gene id: 47917:WN53_RS13560
uniprot id: A0A0F7D234
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

47917:WN53 RS21620
gene id: 47917:WN53_RS21620
uniprot id: A0A0F7D2X9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

47917:WN53 RS03105
gene id: 47917:WN53_RS03105
uniprot id: A0A0F7H7Y8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07990
gene id: 47917:WN53_RS07990
uniprot id: A0A0F7HAA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

47917:WN53 RS01405
gene id: 47917:WN53_RS01405
uniprot id: A0A0F7H7C7
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS19000
gene id: 47917:WN53_RS19000
uniprot id: A0A0F7D3K3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05805
gene id: 47917:WN53_RS05805
uniprot id: A0A0F7H809
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

47917:WN53 RS26610
gene id: 47917:WN53_RS26610
uniprot id: A0A0F7HHP7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

47917:WN53 RS20340
gene id: 47917:WN53_RS20340
uniprot id: A0A0F7D2T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

47917:WN53 RS23835
gene id: 47917:WN53_RS23835
uniprot id: A0A0F7HFJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliT family.
messages: Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
messages: Homodimer. Interacts with FliD and FlhC.
messages: cytosol

47917:WN53 RS00280
gene id: 47917:WN53_RS00280
uniprot id: A0A1Q5V9I7
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

47917:WN53 RS02460
gene id: 47917:WN53_RS02460
uniprot id: A0A0F7H872
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

47917:WN53 RS02985
gene id: 47917:WN53_RS02985
uniprot id: A0A0F7D113
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

47917:WN53 RS05870
gene id: 47917:WN53_RS05870
uniprot id: A0A0F7H819
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

47917:WN53 RS21470
gene id: 47917:WN53_RS21470
uniprot id: A0A0F7HFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS25895
gene id: 47917:WN53_RS25895
uniprot id: A0A0F7D3D1
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

47917:WN53 RS21610
gene id: 47917:WN53_RS21610
uniprot id: A0A0F7HGI6
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

47917:WN53 RS03925
gene id: 47917:WN53_RS03925
uniprot id: A0A0F7H8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS12735
gene id: 47917:WN53_RS12735
uniprot id: A0A0F7HBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

47917:WN53 RS07575
gene id: 47917:WN53_RS07575
uniprot id: A0A0F7H9Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS13995
gene id: 47917:WN53_RS13995
uniprot id: A0A0F7D250
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

47917:WN53 RS15465
gene id: 47917:WN53_RS15465
uniprot id: A0A0F7HBX7
names: Similarity
messages: Belongs to the YjdM family.

47917:WN53 RS13260
gene id: 47917:WN53_RS13260
uniprot id: A0A0F7D224
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

47917:WN53 RS26240
gene id: 47917:WN53_RS26240
uniprot id: A0A0F7D3E4
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS20415
gene id: 47917:WN53_RS20415
uniprot id: A0A0F7HF09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS17655
gene id: 47917:WN53_RS17655
uniprot id: A0A0F7HD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS15265
gene id: 47917:WN53_RS15265
uniprot id: A0A0F7HBV5
names: Similarity
messages: Belongs to the xylose isomerase family.

47917:WN53 RS17245
gene id: 47917:WN53_RS17245
uniprot id: A0A0F7HDU8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

47917:WN53 RS12575
gene id: 47917:WN53_RS12575
uniprot id: A0A0F7HAY9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25925
gene id: 47917:WN53_RS25925
uniprot id: A0A0F7HHE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EcpA/MatB fimbrillin family.
messages: Fimbrium
messages: Self-associates. Forms filaments. Interacts with EcpD.

47917:WN53 RS23740
gene id: 47917:WN53_RS23740
uniprot id: A0A0F7HFJ0
names: Similarity
messages: Belongs to the PhoH family.

47917:WN53 RS23660
gene id: 47917:WN53_RS23660
uniprot id: A0A0F7HGE7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04105
gene id: 47917:WN53_RS04105
uniprot id: A0A0F7H8C4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

47917:WN53 RS12070
gene id: 47917:WN53_RS12070
uniprot id: A0A0F7D1Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

47917:WN53 RS24070
gene id: 47917:WN53_RS24070
uniprot id: A0A0F7HFL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

47917:WN53 RS23960
gene id: 47917:WN53_RS23960
uniprot id: A0A0F7HH87
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

47917:WN53 RS23890
gene id: 47917:WN53_RS23890
uniprot id: A0A0F7HH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

47917:WN53 RS01575
gene id: 47917:WN53_RS01575
uniprot id: A0A0F7D0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS22990
gene id: 47917:WN53_RS22990
uniprot id: A0A0F7HEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

47917:WN53 RS02640
gene id: 47917:WN53_RS02640
uniprot id: A0A0F7D100
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25765
gene id: 47917:WN53_RS25765
uniprot id: A0A0F7HFW9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

47917:WN53 RS10410
gene id: 47917:WN53_RS10410
uniprot id: A0A0F7HA20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIC family. YtfE subfamily.
messages: Cytoplasm
messages: Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
messages: Homodimer.

47917:WN53 RS22510
gene id: 47917:WN53_RS22510
uniprot id: A0A0F7HGV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

47917:WN53 RS07355
gene id: 47917:WN53_RS07355
uniprot id: A0A0F7H9W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

47917:WN53 RS14595
gene id: 47917:WN53_RS14595
uniprot id: A0A0F7D273
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05610
gene id: 47917:WN53_RS05610
uniprot id: A0A0F7H899
names: Cofactor
messages: Can also use Mn(2+) ion.

47917:WN53 RS13415
gene id: 47917:WN53_RS13415
uniprot id: A0A0F7HBA6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

47917:WN53 RS08880
gene id: 47917:WN53_RS08880
uniprot id: A0A0F7HAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

47917:WN53 RS20930
gene id: 47917:WN53_RS20930
uniprot id: A0A0F7D2V4
names: Similarity
messages: Belongs to the DapA family.

47917:WN53 RS05555
gene id: 47917:WN53_RS05555
uniprot id: A0A0F7D1A3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

47917:WN53 RS02970
gene id: 47917:WN53_RS02970
uniprot id: A0A0F7H8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

47917:WN53 RS08205
gene id: 47917:WN53_RS08205
uniprot id: A0A0F7D1J9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

47917:WN53 RS23985
gene id: 47917:WN53_RS23985
uniprot id: A0A0F7HGL1
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

47917:WN53 RS17330
gene id: 47917:WN53_RS17330
uniprot id: A0A0F7HCT1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

47917:WN53 RS18100
gene id: 47917:WN53_RS18100
uniprot id: A0A0F7HEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

47917:WN53 RS26555
gene id: 47917:WN53_RS26555
uniprot id: A0A0F7HG63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

47917:WN53 RS07470
gene id: 47917:WN53_RS07470
uniprot id: A0A0F7H8Y2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

47917:WN53 RS04250
gene id: 47917:WN53_RS04250
uniprot id: A0A0F7H7E8
names: Similarity
messages: Belongs to the archaeal-type GPI family.

47917:WN53 RS13250
gene id: 47917:WN53_RS13250
uniprot id: A0A0F7HCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

47917:WN53 RS14650
gene id: 47917:WN53_RS14650
uniprot id: A0A0F7D275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

47917:WN53 RS18575
gene id: 47917:WN53_RS18575
uniprot id: A0A0F7HDG6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

47917:WN53 RS08090
gene id: 47917:WN53_RS08090
uniprot id: A0A0F7HAC1
names: Similarity
messages: Belongs to the glycosyl hydrolase.

47917:WN53 RS04360
gene id: 47917:WN53_RS04360
uniprot id: A0A0F7H8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

47917:WN53 RS18280
gene id: 47917:WN53_RS18280
uniprot id: A0A0F7D2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS25260
gene id: 47917:WN53_RS25260
uniprot id: A0A0F7HI05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

47917:WN53 RS15765
gene id: 47917:WN53_RS15765
uniprot id: A0A0F7HC85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

47917:WN53 RS04495
gene id: 47917:WN53_RS04495
uniprot id: A0A0F7H8L5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS19150
gene id: 47917:WN53_RS19150
uniprot id: A0A0F7HEC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

47917:WN53 RS04550
gene id: 47917:WN53_RS04550
uniprot id: A0A0F7H7J5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

47917:WN53 RS03895
gene id: 47917:WN53_RS03895
uniprot id: A0A0F7H8F8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS26470
gene id: 47917:WN53_RS26470
uniprot id: A0A0F7HG56
names: Similarity
messages: Belongs to the isochorismate synthase family.

47917:WN53 RS04655
gene id: 47917:WN53_RS04655
uniprot id: A0A0F7H8T4
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

47917:WN53 RS10220
gene id: 47917:WN53_RS10220
uniprot id: A0A0F7HB46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

47917:WN53 RS13350
gene id: 47917:WN53_RS13350
uniprot id: A0A0F7HB26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

47917:WN53 RS03010
gene id: 47917:WN53_RS03010
uniprot id: A0A0F7D114
names: Similarity
messages: Belongs to the GSP E family.

47917:WN53 RS09885
gene id: 47917:WN53_RS09885
uniprot id: A0A0F7H9P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

47917:WN53 RS17960
gene id: 47917:WN53_RS17960
uniprot id: A0A0F7HE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

47917:WN53 RS10240
gene id: 47917:WN53_RS10240
uniprot id: A0A0F7HA05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

47917:WN53 RS00890
gene id: 47917:WN53_RS00890
uniprot id: A0A0F7D0T8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS18710
gene id: 47917:WN53_RS18710
uniprot id: A0A0F7HDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

47917:WN53 RS00700
gene id: 47917:WN53_RS00700
uniprot id: A0A0F7H741
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

47917:WN53 RS14795
gene id: 47917:WN53_RS14795
uniprot id: A0A0F7HCN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS05080
gene id: 47917:WN53_RS05080
uniprot id: A0A0F7H825
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

47917:WN53 RS16090
gene id: 47917:WN53_RS16090
uniprot id: A0A0F7HDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

47917:WN53 RS13660
gene id: 47917:WN53_RS13660
uniprot id: A0A0F7D238
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS22425
gene id: 47917:WN53_RS22425
uniprot id: A0A0F7D309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS04690
gene id: 47917:WN53_RS04690
uniprot id: A0A0F7H8P0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

47917:WN53 RS00715
gene id: 47917:WN53_RS00715
uniprot id: A0A0F7H6A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS19475
gene id: 47917:WN53_RS19475
uniprot id: A0A0F7HEX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

47917:WN53 RS13795
gene id: 47917:WN53_RS13795
uniprot id: A0A0F7HBE8
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family.
messages: Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.

47917:WN53 RS01290
gene id: 47917:WN53_RS01290
uniprot id: A0A0F7H684
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

47917:WN53 RS21465
gene id: 47917:WN53_RS21465
uniprot id: A0A0F7D2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS14210
gene id: 47917:WN53_RS14210
uniprot id: A0A0F7HBF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

47917:WN53 RS04820
gene id: 47917:WN53_RS04820
uniprot id: A0A0F7H7Z2
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

47917:WN53 RS21975
gene id: 47917:WN53_RS21975
uniprot id: A0A0F7HFT0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04190
gene id: 47917:WN53_RS04190
uniprot id: A0A0F7H8L8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

47917:WN53 RS20465
gene id: 47917:WN53_RS20465
uniprot id: A0A0F7HE60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19540
gene id: 47917:WN53_RS19540
uniprot id: A0A0F7HDN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

47917:WN53 RS10205
gene id: 47917:WN53_RS10205
uniprot id: A0A0F7D1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

47917:WN53 RS18800
gene id: 47917:WN53_RS18800
uniprot id: A0A0F7HF85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

47917:WN53 RS01360
gene id: 47917:WN53_RS01360
uniprot id: A0A0F7H7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS14035
gene id: 47917:WN53_RS14035
uniprot id: A0A0F7HBH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

47917:WN53 RS03830
gene id: 47917:WN53_RS03830
uniprot id: A0A0F7D140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS25840
gene id: 47917:WN53_RS25840
uniprot id: A0A0F7D3C9
names: Subunit
messages: Homooctamer.

47917:WN53 RS25280
gene id: 47917:WN53_RS25280
uniprot id: A0A0F7HG94
names: Similarity
messages: Belongs to the GSP C family.

47917:WN53 RS24410
gene id: 47917:WN53_RS24410
uniprot id: A0A0F7D379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

47917:WN53 RS20375
gene id: 47917:WN53_RS20375
uniprot id: A0A0F7HF91
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

47917:WN53 RS00065
gene id: 47917:WN53_RS00065
uniprot id: A0A0F7H6X7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

47917:WN53 RS02010
gene id: 47917:WN53_RS02010
uniprot id: A0A0F7H7I6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS09320
gene id: 47917:WN53_RS09320
uniprot id: A0A0F7H9G2
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

47917:WN53 RS12090
gene id: 47917:WN53_RS12090
uniprot id: A0A0F7HCC4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

47917:WN53 RS23520
gene id: 47917:WN53_RS23520
uniprot id: A0A0F7HFD7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

47917:WN53 RS19190
gene id: 47917:WN53_RS19190
uniprot id: A0A0F7HFI4
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

47917:WN53 RS21965
gene id: 47917:WN53_RS21965
uniprot id: A0A0F7HFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

47917:WN53 RS06380
gene id: 47917:WN53_RS06380
uniprot id: A0A0F7H9A4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

47917:WN53 RS23745
gene id: 47917:WN53_RS23745
uniprot id: A0A0F7HGF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

47917:WN53 RS09230
gene id: 47917:WN53_RS09230
uniprot id: A0A0F7H9N0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

47917:WN53 RS21430
gene id: 47917:WN53_RS21430
uniprot id: A0A0F7HEH6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07970
gene id: 47917:WN53_RS07970
uniprot id: A0A0F7HAG6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

47917:WN53 RS09740
gene id: 47917:WN53_RS09740
uniprot id: A0A0F7D1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS18270
gene id: 47917:WN53_RS18270
uniprot id: A0A0F7HEY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS02905
gene id: 47917:WN53_RS02905
uniprot id: A0A0F7H8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

47917:WN53 RS05280
gene id: 47917:WN53_RS05280
uniprot id: A0A0F7H9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).
messages: Cell inner membrane

47917:WN53 RS02715
gene id: 47917:WN53_RS02715
uniprot id: A0A0F7H730
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

47917:WN53 RS05720
gene id: 47917:WN53_RS05720
uniprot id: A0A0F7H957
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

47917:WN53 RS01780
gene id: 47917:WN53_RS01780
uniprot id: A0A0F7D0X1
names: Similarity
messages: Belongs to the peptidase C59 family.

47917:WN53 RS07540
gene id: 47917:WN53_RS07540
uniprot id: A0A0F7H9W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS15250
gene id: 47917:WN53_RS15250
uniprot id: A0A0F7HCR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS10110
gene id: 47917:WN53_RS10110
uniprot id: A0A0F7HB34
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS07820
gene id: 47917:WN53_RS07820
uniprot id: A0A0F7H966
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

47917:WN53 RS01820
gene id: 47917:WN53_RS01820
uniprot id: A0A0F7H6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS24895
gene id: 47917:WN53_RS24895
uniprot id: A0A0F7HGV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS26040
gene id: 47917:WN53_RS26040
uniprot id: A0A0F7HGI1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

47917:WN53 RS00100
gene id: 47917:WN53_RS00100
uniprot id: A0A0F7H6X9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

47917:WN53 RS15770
gene id: 47917:WN53_RS15770
uniprot id: A0A0F7HC11
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

47917:WN53 RS05270
gene id: 47917:WN53_RS05270
uniprot id: A0A0F7D192
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

47917:WN53 RS19755
gene id: 47917:WN53_RS19755
uniprot id: A0A0F7HF14
names: Similarity
messages: Belongs to the peptidase S41A family.

47917:WN53 RS06970
gene id: 47917:WN53_RS06970
uniprot id: A0A0F7H8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

47917:WN53 RS09215
gene id: 47917:WN53_RS09215
uniprot id: A0A0F7HAB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS06140
gene id: 47917:WN53_RS06140
uniprot id: A0A0F7H9P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

47917:WN53 RS09720
gene id: 47917:WN53_RS09720
uniprot id: A0A0F7H9M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS20405
gene id: 47917:WN53_RS20405
uniprot id: A0A0F7D3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

47917:WN53 RS09755
gene id: 47917:WN53_RS09755
uniprot id: A0A0F7HAY3
names: Similarity
messages: Belongs to the peptidase S51 family.

47917:WN53 RS11555
gene id: 47917:WN53_RS11555
uniprot id: A0A0F7HAK1
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

47917:WN53 RS22850
gene id: 47917:WN53_RS22850
uniprot id: A0A0F7HGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS05515
gene id: 47917:WN53_RS05515
uniprot id: A0A0F7H930
names: Similarity
messages: Belongs to the aspartokinase family.

47917:WN53 RS06320
gene id: 47917:WN53_RS06320
uniprot id: A0A0F7H9R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

47917:WN53 RS05300
gene id: 47917:WN53_RS05300
uniprot id: A0A0F7H901
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19175
gene id: 47917:WN53_RS19175
uniprot id: A0A0F7HER5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

47917:WN53 RS09350
gene id: 47917:WN53_RS09350
uniprot id: A0A0F7H9P6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

47917:WN53 RS24010
gene id: 47917:WN53_RS24010
uniprot id: A0A0F7D3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

47917:WN53 RS24915
gene id: 47917:WN53_RS24915
uniprot id: A0A0F7HFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

47917:WN53 RS09070
gene id: 47917:WN53_RS09070
uniprot id: A0A0F7HAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

47917:WN53 RS12290
gene id: 47917:WN53_RS12290
uniprot id: A0A0F7HBW4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

47917:WN53 RS02950
gene id: 47917:WN53_RS02950
uniprot id: A0A0F7H6X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

47917:WN53 RS04545
gene id: 47917:WN53_RS04545
uniprot id: A0A0F7H7V7
names: Similarity
messages: Belongs to the UxaA family.

47917:WN53 RS20100
gene id: 47917:WN53_RS20100
uniprot id: A0A0F7HF57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

47917:WN53 RS01395
gene id: 47917:WN53_RS01395
uniprot id: A0A0F7H7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

47917:WN53 RS07135
gene id: 47917:WN53_RS07135
uniprot id: A0A0F7H9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

47917:WN53 RS03335
gene id: 47917:WN53_RS03335
uniprot id: A0A0F7D124
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

47917:WN53 RS15410
gene id: 47917:WN53_RS15410
uniprot id: A0A0F7HD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

47917:WN53 RS24225
gene id: 47917:WN53_RS24225
uniprot id: A0A0F7HGS6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

47917:WN53 RS01020
gene id: 47917:WN53_RS01020
uniprot id: A0A0F7H649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

47917:WN53 RS17660
gene id: 47917:WN53_RS17660
uniprot id: A0A0F7HE04
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS12040
gene id: 47917:WN53_RS12040
uniprot id: A0A0F7HAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

47917:WN53 RS14550
gene id: 47917:WN53_RS14550
uniprot id: A0A0F7HDL8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

47917:WN53 RS05395
gene id: 47917:WN53_RS05395
uniprot id: A0A0F7D197
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

47917:WN53 RS25240
gene id: 47917:WN53_RS25240
uniprot id: A0A0F7D3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS01530
gene id: 47917:WN53_RS01530
uniprot id: A0A0F7H7E4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

47917:WN53 RS10985
gene id: 47917:WN53_RS10985
uniprot id: A0A0F7HBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

47917:WN53 RS10210
gene id: 47917:WN53_RS10210
uniprot id: A0A0F7HA01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

47917:WN53 RS17585
gene id: 47917:WN53_RS17585
uniprot id: A0A0F7HCW0
names: Similarity
messages: Belongs to the UPF0145 family.

47917:WN53 RS15900
gene id: 47917:WN53_RS15900
uniprot id: A0A0F7HC27
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

47917:WN53 RS10460
gene id: 47917:WN53_RS10460
uniprot id: A0A0F7HAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

47917:WN53 RS09630
gene id: 47917:WN53_RS09630
uniprot id: A0A0F7D1P6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

47917:WN53 RS07900
gene id: 47917:WN53_RS07900
uniprot id: A0A0F7D1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS02140
gene id: 47917:WN53_RS02140
uniprot id: A0A0F7H7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS22645
gene id: 47917:WN53_RS22645
uniprot id: A0A0F7HG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

47917:WN53 RS17570
gene id: 47917:WN53_RS17570
uniprot id: A0A0F7HDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

47917:WN53 RS09670
gene id: 47917:WN53_RS09670
uniprot id: A0A0F7H9U6
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS14435
gene id: 47917:WN53_RS14435
uniprot id: A0A0F7HBM4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

47917:WN53 RS03030
gene id: 47917:WN53_RS03030
uniprot id: A0A0F7H8F6
names: Similarity
messages: Belongs to the UPF0235 family.

47917:WN53 RS00085
gene id: 47917:WN53_RS00085
uniprot id: A0A0F7D0Q9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

47917:WN53 RS22950
gene id: 47917:WN53_RS22950
uniprot id: A0A0F7HG91
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

47917:WN53 RS06800
gene id: 47917:WN53_RS06800
uniprot id: A0A0F7H8P6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

47917:WN53 RS01025
gene id: 47917:WN53_RS01025
uniprot id: A0A0F7D0U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

47917:WN53 RS14120
gene id: 47917:WN53_RS14120
uniprot id: A0A0F7HCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

47917:WN53 RS15200
gene id: 47917:WN53_RS15200
uniprot id: A0A0F7HC17
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14465
gene id: 47917:WN53_RS14465
uniprot id: A0A0F7HBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

47917:WN53 RS01500
gene id: 47917:WN53_RS01500
uniprot id: A0A0F7D0W1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04135
gene id: 47917:WN53_RS04135
uniprot id: A0A0F7H8C9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

47917:WN53 RS25540
gene id: 47917:WN53_RS25540
uniprot id: A0A0F7HHB5
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

47917:WN53 RS14105
gene id: 47917:WN53_RS14105
uniprot id: A0A0F7D254
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

47917:WN53 RS21615
gene id: 47917:WN53_RS21615
uniprot id: A0A0F7HEI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

47917:WN53 RS25170
gene id: 47917:WN53_RS25170
uniprot id: A0A0F7D3A6
names: Similarity
messages: To H.influenzae HI_0842.

47917:WN53 RS13455
gene id: 47917:WN53_RS13455
uniprot id: A0A0F7D230
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

47917:WN53 RS19490
gene id: 47917:WN53_RS19490
uniprot id: A0A0F7HFM7
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

47917:WN53 RS23145
gene id: 47917:WN53_RS23145
uniprot id: A0A0F7HH06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS05890
gene id: 47917:WN53_RS05890
uniprot id: A0A0F7D1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

47917:WN53 RS11920
gene id: 47917:WN53_RS11920
uniprot id: A0A0F7D1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS21650
gene id: 47917:WN53_RS21650
uniprot id: A0A0F7HEI5
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS25270
gene id: 47917:WN53_RS25270
uniprot id: A0A0F7D3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

47917:WN53 RS10615
gene id: 47917:WN53_RS10615
uniprot id: A0A0F7D1T0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

47917:WN53 RS12000
gene id: 47917:WN53_RS12000
uniprot id: A0A0F7HCA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

47917:WN53 RS00930
gene id: 47917:WN53_RS00930
uniprot id: A0A0F7H7A9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

47917:WN53 RS00070
gene id: 47917:WN53_RS00070
uniprot id: A0A0F7H6Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

47917:WN53 RS20380
gene id: 47917:WN53_RS20380
uniprot id: A0A0F7HF05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

47917:WN53 RS09965
gene id: 47917:WN53_RS09965
uniprot id: A0A0F7D1Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS15955
gene id: 47917:WN53_RS15955
uniprot id: A0A0F7HCA5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

47917:WN53 RS23310
gene id: 47917:WN53_RS23310
uniprot id: A0A0F7HGC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

47917:WN53 RS20235
gene id: 47917:WN53_RS20235
uniprot id: A0A0F7HF73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

47917:WN53 RS08325
gene id: 47917:WN53_RS08325
uniprot id: A0A0F7HAQ3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

47917:WN53 RS00350
gene id: 47917:WN53_RS00350
uniprot id: A0A0F7H6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

47917:WN53 RS26560
gene id: 47917:WN53_RS26560
uniprot id: A0A0F7D3F4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

47917:WN53 RS00870
gene id: 47917:WN53_RS00870
uniprot id: A0A0F7H762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS22240
gene id: 47917:WN53_RS22240
uniprot id: A0A0F7HFY6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

47917:WN53 RS21665
gene id: 47917:WN53_RS21665
uniprot id: A0A0F7HFN9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

47917:WN53 RS24315
gene id: 47917:WN53_RS24315
uniprot id: A0A0F7HFP7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

47917:WN53 RS12610
gene id: 47917:WN53_RS12610
uniprot id: A0A0F7HAT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

47917:WN53 RS13890
gene id: 47917:WN53_RS13890
uniprot id: A0A0F7HCB7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS20975
gene id: 47917:WN53_RS20975
uniprot id: A0A0F7HFF9
names: Similarity
messages: Belongs to the PhzF family.

47917:WN53 RS22235
gene id: 47917:WN53_RS22235
uniprot id: A0A0F7D302
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS04480
gene id: 47917:WN53_RS04480
uniprot id: A0A0F7H7H4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS24150
gene id: 47917:WN53_RS24150
uniprot id: A0A0F7HGM1
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS04375
gene id: 47917:WN53_RS04375
uniprot id: A0A0F7H7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

47917:WN53 RS08570
gene id: 47917:WN53_RS08570
uniprot id: A0A0F7HAT4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

47917:WN53 RS07350
gene id: 47917:WN53_RS07350
uniprot id: A0A0F7H8M3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

47917:WN53 RS17950
gene id: 47917:WN53_RS17950
uniprot id: A0A0F7HD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS22055
gene id: 47917:WN53_RS22055
uniprot id: A0A0F7HEM1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS06220
gene id: 47917:WN53_RS06220
uniprot id: A0A0F7H8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS15525
gene id: 47917:WN53_RS15525
uniprot id: A0A0F7HC60
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

47917:WN53 RS20690
gene id: 47917:WN53_RS20690
uniprot id: A0A0F7HE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

47917:WN53 RS24435
gene id: 47917:WN53_RS24435
uniprot id: A0A0F7D380
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

47917:WN53 RS10200
gene id: 47917:WN53_RS10200
uniprot id: A0A0F7HBE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

47917:WN53 RS01480
gene id: 47917:WN53_RS01480
uniprot id: A0A0F7H6L8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09930
gene id: 47917:WN53_RS09930
uniprot id: A0A0F7HAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

47917:WN53 RS11865
gene id: 47917:WN53_RS11865
uniprot id: A0A0F7HBH3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

47917:WN53 RS23535
gene id: 47917:WN53_RS23535
uniprot id: A0A0F7HGE3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS13210
gene id: 47917:WN53_RS13210
uniprot id: A0A0F7D222
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

47917:WN53 RS13265
gene id: 47917:WN53_RS13265
uniprot id: A0A0F7HB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

47917:WN53 RS08885
gene id: 47917:WN53_RS08885
uniprot id: A0A0F7D1M1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

47917:WN53 RS01060
gene id: 47917:WN53_RS01060
uniprot id: A0A0F7H7C4
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

47917:WN53 RS00080
gene id: 47917:WN53_RS00080
uniprot id: A0A0F7H5Y0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

47917:WN53 RS05690
gene id: 47917:WN53_RS05690
uniprot id: A0A0F7H904
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

47917:WN53 RS04490
gene id: 47917:WN53_RS04490
uniprot id: A0A0F7H8R3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS17015
gene id: 47917:WN53_RS17015
uniprot id: A0A0F7HCP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19485
gene id: 47917:WN53_RS19485
uniprot id: A0A0F7HEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

47917:WN53 RS16055
gene id: 47917:WN53_RS16055
uniprot id: A0A0F7HC53
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

47917:WN53 RS20635
gene id: 47917:WN53_RS20635
uniprot id: A0A0F7HF37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

47917:WN53 RS22155
gene id: 47917:WN53_RS22155
uniprot id: A0A0F7HEN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

47917:WN53 RS22315
gene id: 47917:WN53_RS22315
uniprot id: A0A0F7HGS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

47917:WN53 RS23915
gene id: 47917:WN53_RS23915
uniprot id: A0A0F7HGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

47917:WN53 RS25805
gene id: 47917:WN53_RS25805
uniprot id: A0A0F7D3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS15755
gene id: 47917:WN53_RS15755
uniprot id: A0A0F7HE40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

47917:WN53 RS05830
gene id: 47917:WN53_RS05830
uniprot id: A0A0F7H8C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

47917:WN53 RS00355
gene id: 47917:WN53_RS00355
uniprot id: A0A0F7H7B5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

47917:WN53 RS10325
gene id: 47917:WN53_RS10325
uniprot id: A0A0F7H9V1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

47917:WN53 RS07675
gene id: 47917:WN53_RS07675
uniprot id: A0A0F7HAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS27205
gene id: 47917:WN53_RS27205
uniprot id: A0A1Q5V3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

47917:WN53 RS23895
gene id: 47917:WN53_RS23895
uniprot id: A0A0F7D360
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

47917:WN53 RS22970
gene id: 47917:WN53_RS22970
uniprot id: A0A0F7D328
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

47917:WN53 RS18925
gene id: 47917:WN53_RS18925
uniprot id: A0A0F7D2N2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS21085
gene id: 47917:WN53_RS21085
uniprot id: A0A0F7HG52
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS14570
gene id: 47917:WN53_RS14570
uniprot id: A0A0F7D272
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

47917:WN53 RS11890
gene id: 47917:WN53_RS11890
uniprot id: A0A0F7HBQ8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

47917:WN53 RS10640
gene id: 47917:WN53_RS10640
uniprot id: A0A0F7D1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

47917:WN53 RS04140
gene id: 47917:WN53_RS04140
uniprot id: A0A0F7H8T3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19445
gene id: 47917:WN53_RS19445
uniprot id: A0A0F7HEM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

47917:WN53 RS08655
gene id: 47917:WN53_RS08655
uniprot id: A0A0F7HA98
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15580
gene id: 47917:WN53_RS15580
uniprot id: A0A0F7HHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS02865
gene id: 47917:WN53_RS02865
uniprot id: A0A0F7H824
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

47917:WN53 RS25975
gene id: 47917:WN53_RS25975
uniprot id: A0A0F7HIW8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS11180
gene id: 47917:WN53_RS11180
uniprot id: A0A0F7D1V1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS16940
gene id: 47917:WN53_RS16940
uniprot id: A0A0F7HCQ6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

47917:WN53 RS26490
gene id: 47917:WN53_RS26490
uniprot id: A0A0F7HHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

47917:WN53 RS02875
gene id: 47917:WN53_RS02875
uniprot id: A0A0F7H8D2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

47917:WN53 RS02420
gene id: 47917:WN53_RS02420
uniprot id: A0A0F7H7N6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

47917:WN53 RS07425
gene id: 47917:WN53_RS07425
uniprot id: A0A0F7D1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

47917:WN53 RS25165
gene id: 47917:WN53_RS25165
uniprot id: A0A0F7HH77
names: Similarity
messages: Belongs to the UPF0352 family.

47917:WN53 RS15540
gene id: 47917:WN53_RS15540
uniprot id: A0A0F7D2A7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07010
gene id: 47917:WN53_RS07010
uniprot id: A0A0F7H9N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS11755
gene id: 47917:WN53_RS11755
uniprot id: A0A0F7HAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

47917:WN53 RS21140
gene id: 47917:WN53_RS21140
uniprot id: A0A0F7D2W2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26665
gene id: 47917:WN53_RS26665
uniprot id: A0A0F7HGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

47917:WN53 RS19180
gene id: 47917:WN53_RS19180
uniprot id: A0A0F7HED3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

47917:WN53 RS21515
gene id: 47917:WN53_RS21515
uniprot id: A0A0F7D2X5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

47917:WN53 RS04215
gene id: 47917:WN53_RS04215
uniprot id: A0A0F7H7E6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

47917:WN53 RS24025
gene id: 47917:WN53_RS24025
uniprot id: A0A0F7HH96
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

47917:WN53 RS01940
gene id: 47917:WN53_RS01940
uniprot id: A0A0F7H7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS15740
gene id: 47917:WN53_RS15740
uniprot id: A0A0F7HC07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

47917:WN53 RS26145
gene id: 47917:WN53_RS26145
uniprot id: A0A0F7HHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

47917:WN53 RS10450
gene id: 47917:WN53_RS10450
uniprot id: A0A0F7H9W9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09645
gene id: 47917:WN53_RS09645
uniprot id: A0A0F7H9L2
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

47917:WN53 RS07780
gene id: 47917:WN53_RS07780
uniprot id: A0A0F7H961
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

47917:WN53 RS10160
gene id: 47917:WN53_RS10160
uniprot id: A0A0F7HAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

47917:WN53 RS18040
gene id: 47917:WN53_RS18040
uniprot id: A0A0F7HD29
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

47917:WN53 RS25160
gene id: 47917:WN53_RS25160
uniprot id: A0A0F7HH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

47917:WN53 RS21590
gene id: 47917:WN53_RS21590
uniprot id: A0A0F7HEQ1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15330
gene id: 47917:WN53_RS15330
uniprot id: A0A0F7HC36
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS19460
gene id: 47917:WN53_RS19460
uniprot id: A0A0F7HDM2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

47917:WN53 RS10890
gene id: 47917:WN53_RS10890
uniprot id: A0A0F7HB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS03700
gene id: 47917:WN53_RS03700
uniprot id: A0A0F7HHT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS02660
gene id: 47917:WN53_RS02660
uniprot id: A0A0F7H7Z5
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

47917:WN53 RS15700
gene id: 47917:WN53_RS15700
uniprot id: A0A0F7D2B3
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

47917:WN53 RS21170
gene id: 47917:WN53_RS21170
uniprot id: A0A0F7D2W3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22940
gene id: 47917:WN53_RS22940
uniprot id: A0A0F7HG74
names: Similarity
messages: Belongs to the UPF0162 family.

47917:WN53 RS19825
gene id: 47917:WN53_RS19825
uniprot id: A0A0F7HET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS05130
gene id: 47917:WN53_RS05130
uniprot id: A0A0F7H8Y0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

47917:WN53 RS11945
gene id: 47917:WN53_RS11945
uniprot id: A0A0F7D1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

47917:WN53 RS24440
gene id: 47917:WN53_RS24440
uniprot id: A0A0F7HFC0
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

47917:WN53 RS17940
gene id: 47917:WN53_RS17940
uniprot id: A0A0F7HER8
names: Similarity
messages: Belongs to the peptidase M1 family.

47917:WN53 RS21990
gene id: 47917:WN53_RS21990
uniprot id: A0A0F7HEW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS21560
gene id: 47917:WN53_RS21560
uniprot id: A0A0F7HEP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS08040
gene id: 47917:WN53_RS08040
uniprot id: A0A0F7H996
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

47917:WN53 RS13700
gene id: 47917:WN53_RS13700
uniprot id: A0A0F7HCD7
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

47917:WN53 RS13110
gene id: 47917:WN53_RS13110
uniprot id: A0A0F7D219
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

47917:WN53 RS04315
gene id: 47917:WN53_RS04315
uniprot id: A0A0F7H7S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

47917:WN53 RS05695
gene id: 47917:WN53_RS05695
uniprot id: A0A0F7H9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

47917:WN53 RS08845
gene id: 47917:WN53_RS08845
uniprot id: A0A0F7D1M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS26480
gene id: 47917:WN53_RS26480
uniprot id: A0A0F7HHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Membrane

47917:WN53 RS06525
gene id: 47917:WN53_RS06525
uniprot id: A0A0F7D3H5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

47917:WN53 RS14050
gene id: 47917:WN53_RS14050
uniprot id: A0A0F7D252
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

47917:WN53 RS04090
gene id: 47917:WN53_RS04090
uniprot id: A0A0F7H786
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

47917:WN53 RS25070
gene id: 47917:WN53_RS25070
uniprot id: A0A0F7D3A2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

47917:WN53 RS21630
gene id: 47917:WN53_RS21630
uniprot id: A0A0F7HFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

47917:WN53 RS21950
gene id: 47917:WN53_RS21950
uniprot id: A0A0F7HGM3
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

47917:WN53 RS19320
gene id: 47917:WN53_RS19320
uniprot id: A0A0F7D2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

47917:WN53 RS09295
gene id: 47917:WN53_RS09295
uniprot id: A0A0F7HAQ9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

47917:WN53 RS01900
gene id: 47917:WN53_RS01900
uniprot id: A0A0F7H7N8
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

47917:WN53 RS13725
gene id: 47917:WN53_RS13725
uniprot id: A0A0F7HB68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

47917:WN53 RS05290
gene id: 47917:WN53_RS05290
uniprot id: A0A0F7H7T7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS03150
gene id: 47917:WN53_RS03150
uniprot id: A0A0F7D119
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS18095
gene id: 47917:WN53_RS18095
uniprot id: A0A0F7HDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

47917:WN53 RS22340
gene id: 47917:WN53_RS22340
uniprot id: A0A0F7HFZ9
names: Similarity
messages: Belongs to the asparaginase 1 family.

47917:WN53 RS18275
gene id: 47917:WN53_RS18275
uniprot id: A0A0F7HD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS22930
gene id: 47917:WN53_RS22930
uniprot id: A0A0F7HEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

47917:WN53 RS12035
gene id: 47917:WN53_RS12035
uniprot id: A0A0F7HAR6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS13770
gene id: 47917:WN53_RS13770
uniprot id: A0A0F7D242
names: Similarity
messages: Belongs to the ArsC family.

47917:WN53 RS22615
gene id: 47917:WN53_RS22615
uniprot id: A0A0F7HG38
names: Similarity
messages: Belongs to the pyruvate kinase family.

47917:WN53 RS13515
gene id: 47917:WN53_RS13515
uniprot id: A0A0F7HC64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

47917:WN53 RS12900
gene id: 47917:WN53_RS12900
uniprot id: A0A0F7HC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS24885
gene id: 47917:WN53_RS24885
uniprot id: A0A0F7HFG8
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

47917:WN53 RS16130
gene id: 47917:WN53_RS16130
uniprot id: A0A0F7HDB1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS08165
gene id: 47917:WN53_RS08165
uniprot id: A0A0F7HAJ5
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

47917:WN53 RS02480
gene id: 47917:WN53_RS02480
uniprot id: A0A0F7H6Q6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

47917:WN53 RS10245
gene id: 47917:WN53_RS10245
uniprot id: A0A0F7H9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

47917:WN53 RS26580
gene id: 47917:WN53_RS26580
uniprot id: A0A0F7HIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

47917:WN53 RS17520
gene id: 47917:WN53_RS17520
uniprot id: A0A0F7HEM2
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

47917:WN53 RS05740
gene id: 47917:WN53_RS05740
uniprot id: A0A0F7D1A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

47917:WN53 RS22185
gene id: 47917:WN53_RS22185
uniprot id: A0A0F7HF22
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

47917:WN53 RS22265
gene id: 47917:WN53_RS22265
uniprot id: A0A0F7HFY1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

47917:WN53 RS11565
gene id: 47917:WN53_RS11565
uniprot id: A0A0F7HAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

47917:WN53 RS27085
gene id: 47917:WN53_RS27085
uniprot id: A0A1Q5UY79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

47917:WN53 RS11970
gene id: 47917:WN53_RS11970
uniprot id: A0A0F7D1Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

47917:WN53 RS04155
gene id: 47917:WN53_RS04155
uniprot id: A0A0F7H798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

47917:WN53 RS06035
gene id: 47917:WN53_RS06035
uniprot id: A0A0F7H954
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04975
gene id: 47917:WN53_RS04975
uniprot id: A0A0F7H977
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS12600
gene id: 47917:WN53_RS12600
uniprot id: A0A0F7HCM6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

47917:WN53 RS10185
gene id: 47917:WN53_RS10185
uniprot id: A0A0F7H9T2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

47917:WN53 RS17970
gene id: 47917:WN53_RS17970
uniprot id: A0A0F7HES4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

47917:WN53 RS11955
gene id: 47917:WN53_RS11955
uniprot id: A0A0F7HBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

47917:WN53 RS15185
gene id: 47917:WN53_RS15185
uniprot id: A0A0F7HCQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS18010
gene id: 47917:WN53_RS18010
uniprot id: A0A0F7HD04
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

47917:WN53 RS01080
gene id: 47917:WN53_RS01080
uniprot id: A0A0F7H6G5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

47917:WN53 RS01400
gene id: 47917:WN53_RS01400
uniprot id: A0A0F7D0V7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26205
gene id: 47917:WN53_RS26205
uniprot id: A0A0F7HGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

47917:WN53 RS19005
gene id: 47917:WN53_RS19005
uniprot id: A0A0F7D2N4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09530
gene id: 47917:WN53_RS09530
uniprot id: A0A0F7D1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

47917:WN53 RS25680
gene id: 47917:WN53_RS25680
uniprot id: A0A8I0CQE7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

47917:WN53 RS04365
gene id: 47917:WN53_RS04365
uniprot id: A0A0F7H8J8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

47917:WN53 RS09040
gene id: 47917:WN53_RS09040
uniprot id: A0A0F7HIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS23435
gene id: 47917:WN53_RS23435
uniprot id: A0A0F7HGD2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

47917:WN53 RS16890
gene id: 47917:WN53_RS16890
uniprot id: A0A0F7HDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS23410
gene id: 47917:WN53_RS23410
uniprot id: A0A0F7HH20
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24290
gene id: 47917:WN53_RS24290
uniprot id: A0A0F7HGN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS20940
gene id: 47917:WN53_RS20940
uniprot id: A0A0F7HFF6
names: Similarity
messages: Belongs to the proline racemase family.

47917:WN53 RS27125
gene id: 47917:WN53_RS27125
uniprot id: A0A1Q5VBU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

47917:WN53 RS04570
gene id: 47917:WN53_RS04570
uniprot id: A0A0F7H923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS06675
gene id: 47917:WN53_RS06675
uniprot id: A0A0F7D1E4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

47917:WN53 RS24145
gene id: 47917:WN53_RS24145
uniprot id: A0A0F7HFM5
names: Similarity
messages: Belongs to the DsrB family.

47917:WN53 RS13705
gene id: 47917:WN53_RS13705
uniprot id: A0A0F7HC90
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

47917:WN53 RS07045
gene id: 47917:WN53_RS07045
uniprot id: A0A0F7H9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

47917:WN53 RS08925
gene id: 47917:WN53_RS08925
uniprot id: A0A0F7HAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS15945
gene id: 47917:WN53_RS15945
uniprot id: A0A0F7D2C1
names: Similarity
messages: Belongs to the ModE family.

47917:WN53 RS09790
gene id: 47917:WN53_RS09790
uniprot id: A0A0F7D1Q2
names: Similarity
messages: Belongs to the IMPACT family.

47917:WN53 RS13615
gene id: 47917:WN53_RS13615
uniprot id: A0A0F7HD19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

47917:WN53 RS08285
gene id: 47917:WN53_RS08285
uniprot id: A0A0F7D1K2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

47917:WN53 RS18250
gene id: 47917:WN53_RS18250
uniprot id: A0A0F7HDD0
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS18445
gene id: 47917:WN53_RS18445
uniprot id: A0A0F7HHF8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07140
gene id: 47917:WN53_RS07140
uniprot id: A0A0F7H9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

47917:WN53 RS12500
gene id: 47917:WN53_RS12500
uniprot id: A0A0F7HAX9
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS11770
gene id: 47917:WN53_RS11770
uniprot id: A0A0F7HBG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

47917:WN53 RS02290
gene id: 47917:WN53_RS02290
uniprot id: A0A0F7H845
names: Similarity
messages: Belongs to the RecJ family.

47917:WN53 RS05335
gene id: 47917:WN53_RS05335
uniprot id: A0A0F7H8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

47917:WN53 RS20910
gene id: 47917:WN53_RS20910
uniprot id: A0A0F7HFD2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22960
gene id: 47917:WN53_RS22960
uniprot id: A0A0F7HEU8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

47917:WN53 RS15375
gene id: 47917:WN53_RS15375
uniprot id: A0A0F7HD32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

47917:WN53 RS26200
gene id: 47917:WN53_RS26200
uniprot id: A0A0F7HG23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

47917:WN53 RS15725
gene id: 47917:WN53_RS15725
uniprot id: A0A0F7HE35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

47917:WN53 RS12650
gene id: 47917:WN53_RS12650
uniprot id: A0A0F7HC08
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

47917:WN53 RS20115
gene id: 47917:WN53_RS20115
uniprot id: A0A0F7D2S5
names: Similarity
messages: Belongs to the pyruvate kinase family.

47917:WN53 RS13295
gene id: 47917:WN53_RS13295
uniprot id: A0A0F7HC83
names: Subunit
messages: Monomer.

47917:WN53 RS08215
gene id: 47917:WN53_RS08215
uniprot id: A0A0F7HAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

47917:WN53 RS11070
gene id: 47917:WN53_RS11070
uniprot id: A0A0F7HBD7
names: Similarity
messages: Belongs to the CcdB toxin family.

47917:WN53 RS04955
gene id: 47917:WN53_RS04955
uniprot id: A0A0F7H7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

47917:WN53 RS02295
gene id: 47917:WN53_RS02295
uniprot id: A0A0F7H6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

47917:WN53 RS13080
gene id: 47917:WN53_RS13080
uniprot id: A0A0F7D218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

47917:WN53 RS01095
gene id: 47917:WN53_RS01095
uniprot id: A0A1Q5VFN7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

47917:WN53 RS01580
gene id: 47917:WN53_RS01580
uniprot id: A0A0F7H7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

47917:WN53 RS15575
gene id: 47917:WN53_RS15575
uniprot id: A0A0F7HCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS11415
gene id: 47917:WN53_RS11415
uniprot id: A0A0F7D1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

47917:WN53 RS22125
gene id: 47917:WN53_RS22125
uniprot id: A0A0F7D2Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

47917:WN53 RS00275
gene id: 47917:WN53_RS00275
uniprot id: A0A0F7H5Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

47917:WN53 RS23720
gene id: 47917:WN53_RS23720
uniprot id: A0A0F7HF36
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20215
gene id: 47917:WN53_RS20215
uniprot id: A0A0F7HFW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS21530
gene id: 47917:WN53_RS21530
uniprot id: A0A0F7HFM0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS12315
gene id: 47917:WN53_RS12315
uniprot id: A0A0F7HAP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

47917:WN53 RS17435
gene id: 47917:WN53_RS17435
uniprot id: A0A0F7D2H8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS08870
gene id: 47917:WN53_RS08870
uniprot id: A0A0F7HAL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS07040
gene id: 47917:WN53_RS07040
uniprot id: A0A0F7D1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

47917:WN53 RS25700
gene id: 47917:WN53_RS25700
uniprot id: A0A0F7D3C4
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

47917:WN53 RS19185
gene id: 47917:WN53_RS19185
uniprot id: A0A0F7D2P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

47917:WN53 RS26190
gene id: 47917:WN53_RS26190
uniprot id: A0A0F7HHK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

47917:WN53 RS00495
gene id: 47917:WN53_RS00495
uniprot id: A0A0F7H641
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

47917:WN53 RS09205
gene id: 47917:WN53_RS09205
uniprot id: A0A0F7HHR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS16040
gene id: 47917:WN53_RS16040
uniprot id: A0A0F7HE75
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

47917:WN53 RS21855
gene id: 47917:WN53_RS21855
uniprot id: A0A0F7HEJ5
names: Similarity
messages: Belongs to the PspA/IM30 family.

47917:WN53 RS17550
gene id: 47917:WN53_RS17550
uniprot id: A0A0F7HEM6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

47917:WN53 RS23385
gene id: 47917:WN53_RS23385
uniprot id: A0A0F7HEZ4
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

47917:WN53 RS17270
gene id: 47917:WN53_RS17270
uniprot id: A0A0F7HCV9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

47917:WN53 RS21210
gene id: 47917:WN53_RS21210
uniprot id: A0A0F7HFH0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

47917:WN53 RS09780
gene id: 47917:WN53_RS09780
uniprot id: A0A0F7H9N2
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

47917:WN53 RS01720
gene id: 47917:WN53_RS01720
uniprot id: A0A0F7H7W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

47917:WN53 RS10340
gene id: 47917:WN53_RS10340
uniprot id: A0A0F7HBF9
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

47917:WN53 RS02375
gene id: 47917:WN53_RS02375
uniprot id: A0A0F7H7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

47917:WN53 RS08565
gene id: 47917:WN53_RS08565
uniprot id: A0A0F7D1L1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

47917:WN53 RS00610
gene id: 47917:WN53_RS00610
uniprot id: A0A0F7H696
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

47917:WN53 RS21720
gene id: 47917:WN53_RS21720
uniprot id: A0A0F7HEU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

47917:WN53 RS19100
gene id: 47917:WN53_RS19100
uniprot id: A0A0F7HDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS07325
gene id: 47917:WN53_RS07325
uniprot id: A0A0F7H9V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

47917:WN53 RS00450
gene id: 47917:WN53_RS00450
uniprot id: A0A0F7H6W6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

47917:WN53 RS19415
gene id: 47917:WN53_RS19415
uniprot id: A0A0F7HFL8
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

47917:WN53 RS17845
gene id: 47917:WN53_RS17845
uniprot id: A0A0F7HCY7
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS00795
gene id: 47917:WN53_RS00795
uniprot id: A0A0F7H754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS26460
gene id: 47917:WN53_RS26460
uniprot id: A0A0F7D3F1
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

47917:WN53 RS23975
gene id: 47917:WN53_RS23975
uniprot id: A0A0F7D363
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

47917:WN53 RS09745
gene id: 47917:WN53_RS09745
uniprot id: A0A0F7H9V5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

47917:WN53 RS19480
gene id: 47917:WN53_RS19480
uniprot id: A0A0F7D2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

47917:WN53 RS09145
gene id: 47917:WN53_RS09145
uniprot id: A0A0F7HHX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

47917:WN53 RS15905
gene id: 47917:WN53_RS15905
uniprot id: A0A0F7HD78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

47917:WN53 RS05875
gene id: 47917:WN53_RS05875
uniprot id: A0A0F7H985
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

47917:WN53 RS26020
gene id: 47917:WN53_RS26020
uniprot id: A0A0F7HHF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

47917:WN53 RS14745
gene id: 47917:WN53_RS14745
uniprot id: A0A0F7HBT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

47917:WN53 RS02695
gene id: 47917:WN53_RS02695
uniprot id: A0A0F7D102
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

47917:WN53 RS14265
gene id: 47917:WN53_RS14265
uniprot id: A0A0F7D260
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

47917:WN53 RS09795
gene id: 47917:WN53_RS09795
uniprot id: A0A0F7HAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

47917:WN53 RS01715
gene id: 47917:WN53_RS01715
uniprot id: A0A0F7H7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

47917:WN53 RS02315
gene id: 47917:WN53_RS02315
uniprot id: A0A0F7H7M3
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS15430
gene id: 47917:WN53_RS15430
uniprot id: A0A0F7D2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS25625
gene id: 47917:WN53_RS25625
uniprot id: A0A0F7HI44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS22580
gene id: 47917:WN53_RS22580
uniprot id: A0A0F7HG34
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06950
gene id: 47917:WN53_RS06950
uniprot id: A0A0F7H9M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS08035
gene id: 47917:WN53_RS08035
uniprot id: A0A0F7HAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

47917:WN53 RS23425
gene id: 47917:WN53_RS23425
uniprot id: A0A0F7D343
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

47917:WN53 RS00265
gene id: 47917:WN53_RS00265
uniprot id: A0A0F7D0R5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

47917:WN53 RS06930
gene id: 47917:WN53_RS06930
uniprot id: A0A0F7H8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

47917:WN53 RS11105
gene id: 47917:WN53_RS11105
uniprot id: A0A0F7HBE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

47917:WN53 RS26375
gene id: 47917:WN53_RS26375
uniprot id: A0A0F7HG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS01665
gene id: 47917:WN53_RS01665
uniprot id: A0A0F7H6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

47917:WN53 RS02940
gene id: 47917:WN53_RS02940
uniprot id: A0A0F7H8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

47917:WN53 RS14030
gene id: 47917:WN53_RS14030
uniprot id: A0A0F7HD81
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

47917:WN53 RS15790
gene id: 47917:WN53_RS15790
uniprot id: A0A0F7HE45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

47917:WN53 RS21845
gene id: 47917:WN53_RS21845
uniprot id: A0A370T351
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00305
gene id: 47917:WN53_RS00305
uniprot id: A0A0F7H5R3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23795
gene id: 47917:WN53_RS23795
uniprot id: A0A0F7HF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS04055
gene id: 47917:WN53_RS04055
uniprot id: A0A0F7H8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS24270
gene id: 47917:WN53_RS24270
uniprot id: A0A0F7HHD8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

47917:WN53 RS19345
gene id: 47917:WN53_RS19345
uniprot id: A0A0F7D2P7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

47917:WN53 RS06295
gene id: 47917:WN53_RS06295
uniprot id: A0A0F7H888
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

47917:WN53 RS16165
gene id: 47917:WN53_RS16165
uniprot id: A0A0F7HDC8
names: Similarity
messages: Belongs to the peptidase S11 family.

47917:WN53 RS25590
gene id: 47917:WN53_RS25590
uniprot id: A0A0F7D3C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS06430
gene id: 47917:WN53_RS06430
uniprot id: A0A0F7H8K0
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

47917:WN53 RS04615
gene id: 47917:WN53_RS04615
uniprot id: A0A0F7H7K4
names: Similarity
messages: Belongs to the pirin family.

47917:WN53 RS06935
gene id: 47917:WN53_RS06935
uniprot id: A0A0F7H8G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS22120
gene id: 47917:WN53_RS22120
uniprot id: A0A0F7HEY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

47917:WN53 RS16155
gene id: 47917:WN53_RS16155
uniprot id: A0A448SGB1
names: Subcellular Location Annotation
messages: Cell outer membrane

47917:WN53 RS07800
gene id: 47917:WN53_RS07800
uniprot id: A0A0F7HA10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

47917:WN53 RS26300
gene id: 47917:WN53_RS26300
uniprot id: A0A0F7D3E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS22490
gene id: 47917:WN53_RS22490
uniprot id: A0A0F7HF29
names: Similarity
messages: Belongs to the UPF0260 family.

47917:WN53 RS01785
gene id: 47917:WN53_RS01785
uniprot id: A0A0F7H7Y1
names: Similarity
messages: Belongs to the peptidase S33 family.

47917:WN53 RS16255
gene id: 47917:WN53_RS16255
uniprot id: A0A0F7D2D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

47917:WN53 RS07065
gene id: 47917:WN53_RS07065
uniprot id: A0A0F7D1F8
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

47917:WN53 RS14685
gene id: 47917:WN53_RS14685
uniprot id: A0A0F7HBS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

47917:WN53 RS25550
gene id: 47917:WN53_RS25550
uniprot id: A0A0F7HI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS14480
gene id: 47917:WN53_RS14480
uniprot id: A0A0F7HCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

47917:WN53 RS06165
gene id: 47917:WN53_RS06165
uniprot id: A0A0F7H975
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

47917:WN53 RS11790
gene id: 47917:WN53_RS11790
uniprot id: A0A0F7D1X3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

47917:WN53 RS04235
gene id: 47917:WN53_RS04235
uniprot id: A0A0F7H8X8
names: Similarity
messages: Belongs to the UPF0441 family.

47917:WN53 RS13330
gene id: 47917:WN53_RS13330
uniprot id: A0A0F7HC39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS06725
gene id: 47917:WN53_RS06725
uniprot id: A0A0F7D1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

47917:WN53 RS09890
gene id: 47917:WN53_RS09890
uniprot id: A0A0F7HB01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

47917:WN53 RS24980
gene id: 47917:WN53_RS24980
uniprot id: A0A0F7HFH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS20285
gene id: 47917:WN53_RS20285
uniprot id: A0A0F7HFW8
names: Similarity
messages: Belongs to the GST superfamily.

47917:WN53 RS20595
gene id: 47917:WN53_RS20595
uniprot id: A0A0F7D2U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS11600
gene id: 47917:WN53_RS11600
uniprot id: A0A0F7HAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

47917:WN53 RS12680
gene id: 47917:WN53_RS12680
uniprot id: A0A0F7HC14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

47917:WN53 RS20065
gene id: 47917:WN53_RS20065
uniprot id: A0A370T692
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS10465
gene id: 47917:WN53_RS10465
uniprot id: A0A0F7HBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

47917:WN53 RS20105
gene id: 47917:WN53_RS20105
uniprot id: A0A0F7HEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

47917:WN53 RS18400
gene id: 47917:WN53_RS18400
uniprot id: A0A0F7HD91
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20815
gene id: 47917:WN53_RS20815
uniprot id: A0A0F7HG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

47917:WN53 RS19215
gene id: 47917:WN53_RS19215
uniprot id: A0A0F7HED7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

47917:WN53 RS05960
gene id: 47917:WN53_RS05960
uniprot id: A0A0F7H836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS11925
gene id: 47917:WN53_RS11925
uniprot id: A0A0F7HBQ9
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

47917:WN53 RS02630
gene id: 47917:WN53_RS02630
uniprot id: A0A0F7H7R2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

47917:WN53 RS23830
gene id: 47917:WN53_RS23830
uniprot id: A0A0F7HF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

47917:WN53 RS00640
gene id: 47917:WN53_RS00640
uniprot id: A0A0F7H7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

47917:WN53 RS24445
gene id: 47917:WN53_RS24445
uniprot id: A0A0F7HFR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS25950
gene id: 47917:WN53_RS25950
uniprot id: A0A0F7HHB9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

47917:WN53 RS06105
gene id: 47917:WN53_RS06105
uniprot id: A0A0F7HGG4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

47917:WN53 RS14085
gene id: 47917:WN53_RS14085
uniprot id: A0A0F7HCG8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26015
gene id: 47917:WN53_RS26015
uniprot id: A0A0F7HHE4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02800
gene id: 47917:WN53_RS02800
uniprot id: A0A0F7H816
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

47917:WN53 RS17805
gene id: 47917:WN53_RS17805
uniprot id: A0A0F7HHV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS15530
gene id: 47917:WN53_RS15530
uniprot id: A0A0F7HBY0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

47917:WN53 RS09430
gene id: 47917:WN53_RS09430
uniprot id: A0A0F7HAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

47917:WN53 RS02280
gene id: 47917:WN53_RS02280
uniprot id: A0A0F7H7L8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS17780
gene id: 47917:WN53_RS17780
uniprot id: A0A0F7HCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

47917:WN53 RS26080
gene id: 47917:WN53_RS26080
uniprot id: A0A0F7HHH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS17325
gene id: 47917:WN53_RS17325
uniprot id: A0A0F7HEL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

47917:WN53 RS02455
gene id: 47917:WN53_RS02455
uniprot id: A0A0F7H7P0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

47917:WN53 RS20655
gene id: 47917:WN53_RS20655
uniprot id: A0A0F7HE16
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS10545
gene id: 47917:WN53_RS10545
uniprot id: A0A0F7HA37
names: Similarity
messages: Belongs to the peptidase S13 family.

47917:WN53 RS01670
gene id: 47917:WN53_RS01670
uniprot id: A0A0F7H6E6
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS00670
gene id: 47917:WN53_RS00670
uniprot id: A0A0F7H7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

47917:WN53 RS17540
gene id: 47917:WN53_RS17540
uniprot id: A0A0F7D2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS11645
gene id: 47917:WN53_RS11645
uniprot id: A0A0F7HBF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS09750
gene id: 47917:WN53_RS09750
uniprot id: A0A0F7H9M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

47917:WN53 RS08250
gene id: 47917:WN53_RS08250
uniprot id: A0A0F7HA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

47917:WN53 RS13460
gene id: 47917:WN53_RS13460
uniprot id: A0A0F7HBA8
names: Similarity
messages: Belongs to the IucA/IucC family.

47917:WN53 RS19765
gene id: 47917:WN53_RS19765
uniprot id: A0A0F7HES9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23790
gene id: 47917:WN53_RS23790
uniprot id: A0A0F7HH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS12450
gene id: 47917:WN53_RS12450
uniprot id: A0A0F7HBT8
names: Similarity
messages: Belongs to the peptidase A24 family.

47917:WN53 RS05305
gene id: 47917:WN53_RS05305
uniprot id: A0A0F7H8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

47917:WN53 RS02725
gene id: 47917:WN53_RS02725
uniprot id: A0A292AD48
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

47917:WN53 RS10795
gene id: 47917:WN53_RS10795
uniprot id: A0A0F7D1T7
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

47917:WN53 RS13120
gene id: 47917:WN53_RS13120
uniprot id: A0A0F7HC68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS17290
gene id: 47917:WN53_RS17290
uniprot id: A0A0F7HEL4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

47917:WN53 RS06735
gene id: 47917:WN53_RS06735
uniprot id: A0A0F7H8N8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01630
gene id: 47917:WN53_RS01630
uniprot id: A0A0F7D0W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

47917:WN53 RS12365
gene id: 47917:WN53_RS12365
uniprot id: A0A0F7HCJ8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

47917:WN53 RS00365
gene id: 47917:WN53_RS00365
uniprot id: A0A0F7D0R9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

47917:WN53 RS26035
gene id: 47917:WN53_RS26035
uniprot id: A0A0F7HG00
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS18830
gene id: 47917:WN53_RS18830
uniprot id: A0A0F7HFB2
names: Similarity
messages: Belongs to the HypD family.

47917:WN53 RS22100
gene id: 47917:WN53_RS22100
uniprot id: A0A0F7D2Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

47917:WN53 RS04795
gene id: 47917:WN53_RS04795
uniprot id: A0A0F7H7M4
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

47917:WN53 RS10345
gene id: 47917:WN53_RS10345
uniprot id: A0A0F7D1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS00125
gene id: 47917:WN53_RS00125
uniprot id: A0A0F7H5N4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS09980
gene id: 47917:WN53_RS09980
uniprot id: A0A0F7H9Y0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

47917:WN53 RS24335
gene id: 47917:WN53_RS24335
uniprot id: A0A0F7HHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS21305
gene id: 47917:WN53_RS21305
uniprot id: A0A0F7HG83
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

47917:WN53 RS22560
gene id: 47917:WN53_RS22560
uniprot id: A0A0F7HER2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

47917:WN53 RS02590
gene id: 47917:WN53_RS02590
uniprot id: A0A0F7D0Z8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26055
gene id: 47917:WN53_RS26055
uniprot id: A0A0F7HHH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

47917:WN53 RS20395
gene id: 47917:WN53_RS20395
uniprot id: A0A0F7HDW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

47917:WN53 RS17530
gene id: 47917:WN53_RS17530
uniprot id: A0A0F7HD12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

47917:WN53 RS22600
gene id: 47917:WN53_RS22600
uniprot id: A0A0F7HF42
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

47917:WN53 RS12010
gene id: 47917:WN53_RS12010
uniprot id: A0A0F7HAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

47917:WN53 RS13530
gene id: 47917:WN53_RS13530
uniprot id: A0A0F7HB62
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

47917:WN53 RS01730
gene id: 47917:WN53_RS01730
uniprot id: A0A0F7D0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

47917:WN53 RS25635
gene id: 47917:WN53_RS25635
uniprot id: A0A0F7HGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS23360
gene id: 47917:WN53_RS23360
uniprot id: A0A0F7HFB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

47917:WN53 RS19600
gene id: 47917:WN53_RS19600
uniprot id: A0A0F7D2Q6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS17280
gene id: 47917:WN53_RS17280
uniprot id: A0A0F7D2H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

47917:WN53 RS22275
gene id: 47917:WN53_RS22275
uniprot id: A0A0F7HGR7
names: Similarity
messages: Belongs to the UPF0225 family.

47917:WN53 RS16885
gene id: 47917:WN53_RS16885
uniprot id: A0A0F7HIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS11840
gene id: 47917:WN53_RS11840
uniprot id: A0A0F7HC51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with KefC.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.

47917:WN53 RS15745
gene id: 47917:WN53_RS15745
uniprot id: A0A0F7HD62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

47917:WN53 RS01065
gene id: 47917:WN53_RS01065
uniprot id: A0A0F7H788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

47917:WN53 RS19905
gene id: 47917:WN53_RS19905
uniprot id: A0A0F7HFT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

47917:WN53 RS16045
gene id: 47917:WN53_RS16045
uniprot id: A0A0F7D2C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

47917:WN53 RS10435
gene id: 47917:WN53_RS10435
uniprot id: A0A0F7HBI2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01860
gene id: 47917:WN53_RS01860
uniprot id: A0A0F7HGV6
names: Similarity
messages: Belongs to the SufE family.

47917:WN53 RS17990
gene id: 47917:WN53_RS17990
uniprot id: A0A0F7HE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

47917:WN53 RS10580
gene id: 47917:WN53_RS10580
uniprot id: A0A0F7D1S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS22885
gene id: 47917:WN53_RS22885
uniprot id: A0A0F7D325
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS02900
gene id: 47917:WN53_RS02900
uniprot id: A0A0F7H7V6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07145
gene id: 47917:WN53_RS07145
uniprot id: A0A0F7D1G1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaSR operon in response to L-rhamnose.
messages: Binds DNA as a dimer.
messages: Cytoplasm

47917:WN53 RS11690
gene id: 47917:WN53_RS11690
uniprot id: A0A0F7D1W9
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS10870
gene id: 47917:WN53_RS10870
uniprot id: A0A0F7D1U0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

47917:WN53 RS26030
gene id: 47917:WN53_RS26030
uniprot id: A0A0F7HI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

47917:WN53 RS21685
gene id: 47917:WN53_RS21685
uniprot id: A0A0F7HEU1
names: Similarity
messages: Belongs to the FBPase class 2 family.

47917:WN53 RS22070
gene id: 47917:WN53_RS22070
uniprot id: A0A0F7HFU4
names: Similarity
messages: Belongs to the peptidase S49 family.

47917:WN53 RS21090
gene id: 47917:WN53_RS21090
uniprot id: A0A0F7D2W0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20625
gene id: 47917:WN53_RS20625
uniprot id: A0A0F7D2U3
names: Similarity
messages: Belongs to the UPF0482 family.

47917:WN53 RS14145
gene id: 47917:WN53_RS14145
uniprot id: A0A0F7HCH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

47917:WN53 RS07465
gene id: 47917:WN53_RS07465
uniprot id: A0A0F7HA77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

47917:WN53 RS19375
gene id: 47917:WN53_RS19375
uniprot id: A0A0F7HEW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

47917:WN53 RS13185
gene id: 47917:WN53_RS13185
uniprot id: A0A0F7D221
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

47917:WN53 RS22555
gene id: 47917:WN53_RS22555
uniprot id: A0A0F7HGV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS00905
gene id: 47917:WN53_RS00905
uniprot id: A0A0F7H7K6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS09075
gene id: 47917:WN53_RS09075
uniprot id: A0A0F7D1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS24575
gene id: 47917:WN53_RS24575
uniprot id: A0A0F7HIC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS25095
gene id: 47917:WN53_RS25095
uniprot id: A0A0F7D3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).

47917:WN53 RS22455
gene id: 47917:WN53_RS22455
uniprot id: A0A0F7HEP8
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

47917:WN53 RS00400
gene id: 47917:WN53_RS00400
uniprot id: A0A0F7H623
names: Similarity
messages: Belongs to the GppA/Ppx family.

47917:WN53 RS14450
gene id: 47917:WN53_RS14450
uniprot id: A0A0F7HCJ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS11710
gene id: 47917:WN53_RS11710
uniprot id: A0A0F7HC30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS17810
gene id: 47917:WN53_RS17810
uniprot id: A0A0F7HEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

47917:WN53 RS22385
gene id: 47917:WN53_RS22385
uniprot id: A0A0F7HGT3
names: Similarity
messages: Belongs to the UPF0229 family.

47917:WN53 RS17790
gene id: 47917:WN53_RS17790
uniprot id: A0A0F7HE23
names: Similarity
messages: Belongs to the asparaginase 1 family.

47917:WN53 RS10855
gene id: 47917:WN53_RS10855
uniprot id: A0A0F7HBB1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

47917:WN53 RS04230
gene id: 47917:WN53_RS04230
uniprot id: A0A0F7H8I0
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

47917:WN53 RS20630
gene id: 47917:WN53_RS20630
uniprot id: A0A0F7HFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

47917:WN53 RS26520
gene id: 47917:WN53_RS26520
uniprot id: A0A3S4X8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

47917:WN53 RS04070
gene id: 47917:WN53_RS04070
uniprot id: A0A0F7H8B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS05430
gene id: 47917:WN53_RS05430
uniprot id: A0A0F7H8X1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

47917:WN53 RS10035
gene id: 47917:WN53_RS10035
uniprot id: A0A0F7H9Y4
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

47917:WN53 RS07555
gene id: 47917:WN53_RS07555
uniprot id: A0A0F7H928
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

47917:WN53 RS23980
gene id: 47917:WN53_RS23980
uniprot id: A0A0F7HGK3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

47917:WN53 RS10415
gene id: 47917:WN53_RS10415
uniprot id: A0A0F7H9W2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

47917:WN53 RS01110
gene id: 47917:WN53_RS01110
uniprot id: A0A0F7H6G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

47917:WN53 RS26360
gene id: 47917:WN53_RS26360
uniprot id: A0A0F7HHK8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS11775
gene id: 47917:WN53_RS11775
uniprot id: A0A1Q5VIL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS26000
gene id: 47917:WN53_RS26000
uniprot id: A0A0F7D3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
messages: Belongs to the flk family.
messages: Cell inner membrane

47917:WN53 RS16000
gene id: 47917:WN53_RS16000
uniprot id: A0A0F7HD92
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

47917:WN53 RS09585
gene id: 47917:WN53_RS09585
uniprot id: A0A0F7H9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS09220
gene id: 47917:WN53_RS09220
uniprot id: A0A0F7D1N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

47917:WN53 RS19395
gene id: 47917:WN53_RS19395
uniprot id: A0A0F7D2P9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS13310
gene id: 47917:WN53_RS13310
uniprot id: A0A0F7D225
names: Similarity
messages: Belongs to the peptidase M17 family.

47917:WN53 RS06910
gene id: 47917:WN53_RS06910
uniprot id: A0A0F7H9N3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS14640
gene id: 47917:WN53_RS14640
uniprot id: A0A0F7HCL0
names: Similarity
messages: Belongs to the hyi family.

47917:WN53 RS26590
gene id: 47917:WN53_RS26590
uniprot id: A0A0F7HG82
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS06005
gene id: 47917:WN53_RS06005
uniprot id: A0A0F7H949
names: Similarity
messages: Belongs to the PhzF family.

47917:WN53 RS21175
gene id: 47917:WN53_RS21175
uniprot id: A0A0F7HFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

47917:WN53 RS19935
gene id: 47917:WN53_RS19935
uniprot id: A0A0F7HFT6
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

47917:WN53 RS09460
gene id: 47917:WN53_RS09460
uniprot id: A0A0F7HAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

47917:WN53 RS04960
gene id: 47917:WN53_RS04960
uniprot id: A0A0F7H8W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS22750
gene id: 47917:WN53_RS22750
uniprot id: A0A0F7HG58
names: Similarity
messages: Belongs to the UPF0502 family.

47917:WN53 RS07450
gene id: 47917:WN53_RS07450
uniprot id: A0A0F7D1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

47917:WN53 RS13470
gene id: 47917:WN53_RS13470
uniprot id: A0A0F7HCA4
names: Similarity
messages: Belongs to the IucA/IucC family.

47917:WN53 RS09315
gene id: 47917:WN53_RS09315
uniprot id: A0A0F7D1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

47917:WN53 RS05785
gene id: 47917:WN53_RS05785
uniprot id: A0A0F7H918
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

47917:WN53 RS04965
gene id: 47917:WN53_RS04965
uniprot id: A0A0F7H8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeB.

47917:WN53 RS24230
gene id: 47917:WN53_RS24230
uniprot id: A0A0F7HHD6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

47917:WN53 RS10600
gene id: 47917:WN53_RS10600
uniprot id: A0A0F7HB90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

47917:WN53 RS09525
gene id: 47917:WN53_RS09525
uniprot id: A0A0F7HAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

47917:WN53 RS17620
gene id: 47917:WN53_RS17620
uniprot id: A0A0F7HCW3
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

47917:WN53 RS09180
gene id: 47917:WN53_RS09180
uniprot id: A0A0F7HAB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

47917:WN53 RS10390
gene id: 47917:WN53_RS10390
uniprot id: A0A0F7HB58
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

47917:WN53 RS13540
gene id: 47917:WN53_RS13540
uniprot id: A0A0F7HCB4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

47917:WN53 RS24505
gene id: 47917:WN53_RS24505
uniprot id: A0A0F7D382
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS05310
gene id: 47917:WN53_RS05310
uniprot id: A0A0F7H9C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

47917:WN53 RS07345
gene id: 47917:WN53_RS07345
uniprot id: A0A0F7D1G9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS26250
gene id: 47917:WN53_RS26250
uniprot id: A0A0F7HHK3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02915
gene id: 47917:WN53_RS02915
uniprot id: A0A0F7H755
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

47917:WN53 RS11340
gene id: 47917:WN53_RS11340
uniprot id: A0A0F7HBX6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

47917:WN53 RS25615
gene id: 47917:WN53_RS25615
uniprot id: A0A0F7D3C1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

47917:WN53 RS12685
gene id: 47917:WN53_RS12685
uniprot id: A0A0F7HBW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

47917:WN53 RS11640
gene id: 47917:WN53_RS11640
uniprot id: A0A0F7D1W7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

47917:WN53 RS04325
gene id: 47917:WN53_RS04325
uniprot id: A0A0F7H8N9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

47917:WN53 RS26245
gene id: 47917:WN53_RS26245
uniprot id: A0A0F7HGK4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS10290
gene id: 47917:WN53_RS10290
uniprot id: A0A0F7H9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

47917:WN53 RS26085
gene id: 47917:WN53_RS26085
uniprot id: A0A0F7HHH8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

47917:WN53 RS14260
gene id: 47917:WN53_RS14260
uniprot id: A0A0F7HDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

47917:WN53 RS00765
gene id: 47917:WN53_RS00765
uniprot id: A0A0F7H749
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

47917:WN53 RS19950
gene id: 47917:WN53_RS19950
uniprot id: A0A0F7HDZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

47917:WN53 RS00030
gene id: 47917:WN53_RS00030
uniprot id: A0A0F7D0Q7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

47917:WN53 RS13255
gene id: 47917:WN53_RS13255
uniprot id: A0A0F7HB98
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

47917:WN53 RS11800
gene id: 47917:WN53_RS11800
uniprot id: A0A0F7HBG9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

47917:WN53 RS18200
gene id: 47917:WN53_RS18200
uniprot id: A0A0F7HD71
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS22215
gene id: 47917:WN53_RS22215
uniprot id: A0A0F7HGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS00410
gene id: 47917:WN53_RS00410
uniprot id: A0A0F7H704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

47917:WN53 RS09715
gene id: 47917:WN53_RS09715
uniprot id: A0A0F7D1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

47917:WN53 RS02835
gene id: 47917:WN53_RS02835
uniprot id: A0A0F7D107
names: Similarity
messages: Belongs to the fabD family.

47917:WN53 RS23910
gene id: 47917:WN53_RS23910
uniprot id: A0A0F7HGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

47917:WN53 RS11620
gene id: 47917:WN53_RS11620
uniprot id: A0A0F7HC15
names: Similarity
messages: Belongs to the Smp family.

47917:WN53 RS09560
gene id: 47917:WN53_RS09560
uniprot id: A0A0F7HAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS12510
gene id: 47917:WN53_RS12510
uniprot id: A0A0F7HAS2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

47917:WN53 RS10630
gene id: 47917:WN53_RS10630
uniprot id: A0A0F7HB95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

47917:WN53 RS06550
gene id: 47917:WN53_RS06550
uniprot id: A0A0F7H9G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

47917:WN53 RS17675
gene id: 47917:WN53_RS17675
uniprot id: A0A0F7HEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

47917:WN53 RS25880
gene id: 47917:WN53_RS25880
uniprot id: A0A0F7HGG2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS06325
gene id: 47917:WN53_RS06325
uniprot id: A0A0F7H8I8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

47917:WN53 RS08000
gene id: 47917:WN53_RS08000
uniprot id: A0A0F7D1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

47917:WN53 RS04940
gene id: 47917:WN53_RS04940
uniprot id: A0A0F7H972
names: Similarity
messages: Belongs to the peptidase U62 family.

47917:WN53 RS11100
gene id: 47917:WN53_RS11100
uniprot id: A0A0F7D1U8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

47917:WN53 RS22360
gene id: 47917:WN53_RS22360
uniprot id: A0A0F7HF16
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

47917:WN53 RS17510
gene id: 47917:WN53_RS17510
uniprot id: A0A0F7HDK4
names: Subunit
messages: Monomer.

47917:WN53 RS12015
gene id: 47917:WN53_RS12015
uniprot id: A0A0F7HBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

47917:WN53 RS05750
gene id: 47917:WN53_RS05750
uniprot id: A0A0F7H962
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS02730
gene id: 47917:WN53_RS02730
uniprot id: A0A0F7D103
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

47917:WN53 RS12665
gene id: 47917:WN53_RS12665
uniprot id: A0A0F7D205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS04800
gene id: 47917:WN53_RS04800
uniprot id: A0A0F7H8U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

47917:WN53 RS10570
gene id: 47917:WN53_RS10570
uniprot id: A0A0F7HBJ2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

47917:WN53 RS12180
gene id: 47917:WN53_RS12180
uniprot id: A0A0F7HBV4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

47917:WN53 RS01975
gene id: 47917:WN53_RS01975
uniprot id: A0A0F7D0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane

47917:WN53 RS10025
gene id: 47917:WN53_RS10025
uniprot id: A0A0F7HAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

47917:WN53 RS00075
gene id: 47917:WN53_RS00075
uniprot id: A0A0F7H776
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

47917:WN53 RS08805
gene id: 47917:WN53_RS08805
uniprot id: A0A0F7HAW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

47917:WN53 RS01475
gene id: 47917:WN53_RS01475
uniprot id: A0A0F7D0W0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS02540
gene id: 47917:WN53_RS02540
uniprot id: A0A0F7D0Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS00325
gene id: 47917:WN53_RS00325
uniprot id: A0A0F7H7B1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS05255
gene id: 47917:WN53_RS05255
uniprot id: A0A0F7D3H3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

47917:WN53 RS06535
gene id: 47917:WN53_RS06535
uniprot id: A0A0F7D1D9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

47917:WN53 RS02775
gene id: 47917:WN53_RS02775
uniprot id: A0A0F7H8B8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

47917:WN53 RS05570
gene id: 47917:WN53_RS05570
uniprot id: A0A0F7H9F9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

47917:WN53 RS14680
gene id: 47917:WN53_RS14680
uniprot id: A0A0F7HDN6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15360
gene id: 47917:WN53_RS15360
uniprot id: A0A0F7HDY3
names: Similarity
messages: Belongs to the UPF0250 family.

47917:WN53 RS01745
gene id: 47917:WN53_RS01745
uniprot id: A0A0F7H7H2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

47917:WN53 RS06370
gene id: 47917:WN53_RS06370
uniprot id: A0A0F7D1D3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

47917:WN53 RS05485
gene id: 47917:WN53_RS05485
uniprot id: A0A0F7H925
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).
messages: sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE.

47917:WN53 RS06740
gene id: 47917:WN53_RS06740
uniprot id: A0A0F7H8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS21925
gene id: 47917:WN53_RS21925
uniprot id: A0A0F7HEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

47917:WN53 RS07160
gene id: 47917:WN53_RS07160
uniprot id: A0A0F7H8J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS24015
gene id: 47917:WN53_RS24015
uniprot id: A0A0F7HGK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

47917:WN53 RS17385
gene id: 47917:WN53_RS17385
uniprot id: A0A0F7D2H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

47917:WN53 RS01005
gene id: 47917:WN53_RS01005
uniprot id: A0A0F7H778
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

47917:WN53 RS00675
gene id: 47917:WN53_RS00675
uniprot id: A0A0F7D0T0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

47917:WN53 RS11750
gene id: 47917:WN53_RS11750
uniprot id: A0A0F7HAM5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS18150
gene id: 47917:WN53_RS18150
uniprot id: A0A0F7D3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS17080
gene id: 47917:WN53_RS17080
uniprot id: A0A0F7D2G4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07490
gene id: 47917:WN53_RS07490
uniprot id: A0A0F7H9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

47917:WN53 RS05990
gene id: 47917:WN53_RS05990
uniprot id: A0A0F7D1B9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15365
gene id: 47917:WN53_RS15365
uniprot id: A0A0F7HC40
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

47917:WN53 RS11820
gene id: 47917:WN53_RS11820
uniprot id: A0A0F7D1X4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

47917:WN53 RS01365
gene id: 47917:WN53_RS01365
uniprot id: A0A0F7H7C3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS22680
gene id: 47917:WN53_RS22680
uniprot id: A0A0F7D318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

47917:WN53 RS15435
gene id: 47917:WN53_RS15435
uniprot id: A0A0F7HBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS01845
gene id: 47917:WN53_RS01845
uniprot id: A0A0F7H7H8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS16715
gene id: 47917:WN53_RS16715
uniprot id: A0A0F7HCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

47917:WN53 RS12675
gene id: 47917:WN53_RS12675
uniprot id: A0A0F7HAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

47917:WN53 RS00570
gene id: 47917:WN53_RS00570
uniprot id: A0A0F7H5Y1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

47917:WN53 RS23580
gene id: 47917:WN53_RS23580
uniprot id: A0A0F7D349
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

47917:WN53 RS26400
gene id: 47917:WN53_RS26400
uniprot id: A0A0F7HIC2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

47917:WN53 RS03285
gene id: 47917:WN53_RS03285
uniprot id: A0A0F7H8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

47917:WN53 RS14535
gene id: 47917:WN53_RS14535
uniprot id: A0A0F7HCM4
names: Similarity
messages: Belongs to the CdaR family.

47917:WN53 RS07225
gene id: 47917:WN53_RS07225
uniprot id: A0A0F7H8K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

47917:WN53 RS13945
gene id: 47917:WN53_RS13945
uniprot id: A0A0F7D248
names: Similarity
messages: Belongs to the pirin family.

47917:WN53 RS23950
gene id: 47917:WN53_RS23950
uniprot id: A0A0F7D362
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

47917:WN53 RS26525
gene id: 47917:WN53_RS26525
uniprot id: A0A0F7HGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS05510
gene id: 47917:WN53_RS05510
uniprot id: A0A0F7H7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

47917:WN53 RS04950
gene id: 47917:WN53_RS04950
uniprot id: A0A0F7H808
names: Similarity
messages: Belongs to the barstar family.

47917:WN53 RS13630
gene id: 47917:WN53_RS13630
uniprot id: A0A0F7HCC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

47917:WN53 RS13040
gene id: 47917:WN53_RS13040
uniprot id: A0A0F7HB70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZraP family.
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.
messages: Periplasm

47917:WN53 RS01305
gene id: 47917:WN53_RS01305
uniprot id: A0A0F7H7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

47917:WN53 RS08270
gene id: 47917:WN53_RS08270
uniprot id: A0A0F7H9C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

47917:WN53 RS13320
gene id: 47917:WN53_RS13320
uniprot id: A0A0F7HB21
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

47917:WN53 RS18815
gene id: 47917:WN53_RS18815
uniprot id: A0A0F7D2M8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

47917:WN53 RS04065
gene id: 47917:WN53_RS04065
uniprot id: A0A0F7D3H1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS17285
gene id: 47917:WN53_RS17285
uniprot id: A0A0F7HDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS01495
gene id: 47917:WN53_RS01495
uniprot id: A0A0F7H7E1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS15705
gene id: 47917:WN53_RS15705
uniprot id: A0A0F7HD60
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

47917:WN53 RS11140
gene id: 47917:WN53_RS11140
uniprot id: A0A0F7HBE7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

47917:WN53 RS17075
gene id: 47917:WN53_RS17075
uniprot id: A0A0F7HCR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS27845
gene id: 47917:WN53_RS27845
uniprot id: A0A0F7H974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

47917:WN53 RS17365
gene id: 47917:WN53_RS17365
uniprot id: A0A0F7HCT4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

47917:WN53 RS06160
gene id: 47917:WN53_RS06160
uniprot id: A0A0F7H9D1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

47917:WN53 RS09310
gene id: 47917:WN53_RS09310
uniprot id: A0A0F7H9P0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

47917:WN53 RS24680
gene id: 47917:WN53_RS24680
uniprot id: A0A0F7HGR8
names: Similarity
messages: Belongs to the DapA family.

47917:WN53 RS04970
gene id: 47917:WN53_RS04970
uniprot id: A0A0F7D181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

47917:WN53 RS02230
gene id: 47917:WN53_RS02230
uniprot id: A0A0F7HHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS19200
gene id: 47917:WN53_RS19200
uniprot id: A0A1Q5VAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

47917:WN53 RS10565
gene id: 47917:WN53_RS10565
uniprot id: A0A0F7HAV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS15830
gene id: 47917:WN53_RS15830
uniprot id: A0A0F7HC22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

47917:WN53 RS11680
gene id: 47917:WN53_RS11680
uniprot id: A0A0F7HC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

47917:WN53 RS14750
gene id: 47917:WN53_RS14750
uniprot id: A0A0F7D279
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

47917:WN53 RS11765
gene id: 47917:WN53_RS11765
uniprot id: A0A0F7D1X2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

47917:WN53 RS06890
gene id: 47917:WN53_RS06890
uniprot id: A0A0F7D1F1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

47917:WN53 RS24430
gene id: 47917:WN53_RS24430
uniprot id: A0A0F7HHF3
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

47917:WN53 RS05530
gene id: 47917:WN53_RS05530
uniprot id: A0A0F7H9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS02675
gene id: 47917:WN53_RS02675
uniprot id: A0A0F7H8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

47917:WN53 RS07475
gene id: 47917:WN53_RS07475
uniprot id: A0A1J7XDA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS23820
gene id: 47917:WN53_RS23820
uniprot id: A0A0F7HGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

47917:WN53 RS00475
gene id: 47917:WN53_RS00475
uniprot id: A0A0F7D0S3
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

47917:WN53 RS10320
gene id: 47917:WN53_RS10320
uniprot id: A0A0F7D1R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

47917:WN53 RS04710
gene id: 47917:WN53_RS04710
uniprot id: A0A0F7H7L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

47917:WN53 RS11720
gene id: 47917:WN53_RS11720
uniprot id: A0A0F7HAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

47917:WN53 RS07185
gene id: 47917:WN53_RS07185
uniprot id: A0A0F7H8U4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS09865
gene id: 47917:WN53_RS09865
uniprot id: A0A0F7HAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

47917:WN53 RS18645
gene id: 47917:WN53_RS18645
uniprot id: A0A0F7HEF5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

47917:WN53 RS08290
gene id: 47917:WN53_RS08290
uniprot id: A0A0F7HA56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS01910
gene id: 47917:WN53_RS01910
uniprot id: A0A0F7D3G2
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

47917:WN53 RS20765
gene id: 47917:WN53_RS20765
uniprot id: A0A0F7HFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

47917:WN53 RS26625
gene id: 47917:WN53_RS26625
uniprot id: A0A0F7HG84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

47917:WN53 RS27850
gene id: 47917:WN53_RS27850
uniprot id: A0A0F7D1B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

47917:WN53 RS11940
gene id: 47917:WN53_RS11940
uniprot id: A0A0F7HAQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

47917:WN53 RS07980
gene id: 47917:WN53_RS07980
uniprot id: A0A0F7H986
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

47917:WN53 RS15225
gene id: 47917:WN53_RS15225
uniprot id: A0A0F7HDW9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07705
gene id: 47917:WN53_RS07705
uniprot id: A0A0F7D1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

47917:WN53 RS06530
gene id: 47917:WN53_RS06530
uniprot id: A0A0F7H8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

47917:WN53 RS01100
gene id: 47917:WN53_RS01100
uniprot id: A0A0F7D0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

47917:WN53 RS06990
gene id: 47917:WN53_RS06990
uniprot id: A0A0F7D1F5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

47917:WN53 RS17140
gene id: 47917:WN53_RS17140
uniprot id: A0A0F7HCR9
names: Similarity
messages: Belongs to the FGGY kinase family.

47917:WN53 RS15455
gene id: 47917:WN53_RS15455
uniprot id: A0A0F7D2A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

47917:WN53 RS05260
gene id: 47917:WN53_RS05260
uniprot id: A0A0F7H7T3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

47917:WN53 RS02565
gene id: 47917:WN53_RS02565
uniprot id: A0A0F7D0Z7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS18930
gene id: 47917:WN53_RS18930
uniprot id: A0A0F7HEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

47917:WN53 RS24490
gene id: 47917:WN53_RS24490
uniprot id: A0A0F7HFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS16460
gene id: 47917:WN53_RS16460
uniprot id: A0A0F7D2E1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

47917:WN53 RS20165
gene id: 47917:WN53_RS20165
uniprot id: A0A0F7HE24
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

47917:WN53 RS14255
gene id: 47917:WN53_RS14255
uniprot id: A0A0F7HCH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

47917:WN53 RS15915
gene id: 47917:WN53_RS15915
uniprot id: A0A0F7HE59
names: Similarity
messages: Belongs to the aldose epimerase family.

47917:WN53 RS06260
gene id: 47917:WN53_RS06260
uniprot id: A0A0F7D1C9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

47917:WN53 RS00840
gene id: 47917:WN53_RS00840
uniprot id: A0A0F7D0T6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22305
gene id: 47917:WN53_RS22305
uniprot id: A0A0F7HFY5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

47917:WN53 RS24545
gene id: 47917:WN53_RS24545
uniprot id: A0A0F7HHF9
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS22640
gene id: 47917:WN53_RS22640
uniprot id: A0A0F7HF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

47917:WN53 RS12335
gene id: 47917:WN53_RS12335
uniprot id: A0A0F7HCG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

47917:WN53 RS18055
gene id: 47917:WN53_RS18055
uniprot id: A0A0F7D2K2
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS14315
gene id: 47917:WN53_RS14315
uniprot id: A0A0F7D262
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

47917:WN53 RS17165
gene id: 47917:WN53_RS17165
uniprot id: A0A0F7HEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

47917:WN53 RS24665
gene id: 47917:WN53_RS24665
uniprot id: A0A0F7HFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

47917:WN53 RS05190
gene id: 47917:WN53_RS05190
uniprot id: A0A0F7H7S4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

47917:WN53 RS07150
gene id: 47917:WN53_RS07150
uniprot id: A0A0F7HA46
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaBAD and rhaT operons.
messages: Binds DNA as a dimer.
messages: Cytoplasm

47917:WN53 RS05940
gene id: 47917:WN53_RS05940
uniprot id: A0A0F7D1B7
names: Similarity
messages: Belongs to the NAPRTase family.

47917:WN53 RS20345
gene id: 47917:WN53_RS20345
uniprot id: A0A0F7HF88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

47917:WN53 RS02975
gene id: 47917:WN53_RS02975
uniprot id: A0A0F7H763
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

47917:WN53 RS14560
gene id: 47917:WN53_RS14560
uniprot id: A0A0F7HBN9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14620
gene id: 47917:WN53_RS14620
uniprot id: A0A0F7D274
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS04045
gene id: 47917:WN53_RS04045
uniprot id: A0A0F7H782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

47917:WN53 RS23905
gene id: 47917:WN53_RS23905
uniprot id: A0A0F7HFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

47917:WN53 RS09475
gene id: 47917:WN53_RS09475
uniprot id: A0A4U9U0Y6
names: Subcellular Location Annotation
messages: Cell outer membrane

47917:WN53 RS13200
gene id: 47917:WN53_RS13200
uniprot id: A0A0F7HB06
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

47917:WN53 RS09945
gene id: 47917:WN53_RS09945
uniprot id: A0A0F7H9X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

47917:WN53 RS21920
gene id: 47917:WN53_RS21920
uniprot id: A0A0F7HIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

47917:WN53 RS25015
gene id: 47917:WN53_RS25015
uniprot id: A0A0F7HFI1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

47917:WN53 RS07435
gene id: 47917:WN53_RS07435
uniprot id: A0A0F7HA74
names: Similarity
messages: Belongs to the peptidase C59 family.

47917:WN53 RS11900
gene id: 47917:WN53_RS11900
uniprot id: A0A0F7HBH5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

47917:WN53 RS07985
gene id: 47917:WN53_RS07985
uniprot id: A0A0F7H906
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

47917:WN53 RS12605
gene id: 47917:WN53_RS12605
uniprot id: A0A0F7HAZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

47917:WN53 RS00415
gene id: 47917:WN53_RS00415
uniprot id: A0A0F7H6W0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS02750
gene id: 47917:WN53_RS02750
uniprot id: A0A0F7H733
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

47917:WN53 RS21760
gene id: 47917:WN53_RS21760
uniprot id: A0A0F7HFT2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

47917:WN53 RS01345
gene id: 47917:WN53_RS01345
uniprot id: A0A0F7D0V5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09760
gene id: 47917:WN53_RS09760
uniprot id: A0A0F7HAJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

47917:WN53 RS20480
gene id: 47917:WN53_RS20480
uniprot id: A0A0F7HFA0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

47917:WN53 RS23260
gene id: 47917:WN53_RS23260
uniprot id: A0A0F7HGA2
names: Similarity
messages: Belongs to the peptidase S24 family.

47917:WN53 RS09080
gene id: 47917:WN53_RS09080
uniprot id: A0A0F7HAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS05605
gene id: 47917:WN53_RS05605
uniprot id: A0A0F7D1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

47917:WN53 RS19970
gene id: 47917:WN53_RS19970
uniprot id: A0A0F7HFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

47917:WN53 RS25890
gene id: 47917:WN53_RS25890
uniprot id: A0A0F7HHD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

47917:WN53 RS04345
gene id: 47917:WN53_RS04345
uniprot id: A0A0F7H7S7
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

47917:WN53 RS17895
gene id: 47917:WN53_RS17895
uniprot id: A0A0F7HDQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

47917:WN53 RS16805
gene id: 47917:WN53_RS16805
uniprot id: A0A0F7HEG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EcpA/MatB fimbrillin family.
messages: Fimbrium
messages: Self-associates. Forms filaments. Interacts with EcpD.

47917:WN53 RS13535
gene id: 47917:WN53_RS13535
uniprot id: A0A0F7D233
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

47917:WN53 RS14500
gene id: 47917:WN53_RS14500
uniprot id: A0A0F7HBN1
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS21425
gene id: 47917:WN53_RS21425
uniprot id: A0A0F7HEB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

47917:WN53 RS23615
gene id: 47917:WN53_RS23615
uniprot id: A0A0F7HF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

47917:WN53 RS19980
gene id: 47917:WN53_RS19980
uniprot id: A0A0F7HDR7
names: Similarity
messages: Belongs to the peptidase C40 family.

47917:WN53 RS17275
gene id: 47917:WN53_RS17275
uniprot id: A0A0F7HDV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

47917:WN53 RS19995
gene id: 47917:WN53_RS19995
uniprot id: A0A0F7HF44
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

47917:WN53 RS15640
gene id: 47917:WN53_RS15640
uniprot id: A0A0F7HCY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

47917:WN53 RS04650
gene id: 47917:WN53_RS04650
uniprot id: A0A0F7H7K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

47917:WN53 RS14250
gene id: 47917:WN53_RS14250
uniprot id: A0A0F7HCI6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22165
gene id: 47917:WN53_RS22165
uniprot id: A0A0F7HEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

47917:WN53 RS22050
gene id: 47917:WN53_RS22050
uniprot id: A0A0F7D2Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

47917:WN53 RS12785
gene id: 47917:WN53_RS12785
uniprot id: A0A0F7HCP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS04175
gene id: 47917:WN53_RS04175
uniprot id: A0A0F7H8T7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS21080
gene id: 47917:WN53_RS21080
uniprot id: A0A0F7HFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS19170
gene id: 47917:WN53_RS19170
uniprot id: A0A0F7HDR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

47917:WN53 RS03890
gene id: 47917:WN53_RS03890
uniprot id: A0A0F7H761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

47917:WN53 RS17025
gene id: 47917:WN53_RS17025
uniprot id: A0A0F7D2G2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

47917:WN53 RS14775
gene id: 47917:WN53_RS14775
uniprot id: A0A0F7D280
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

47917:WN53 RS07655
gene id: 47917:WN53_RS07655
uniprot id: A0A0F7D1H9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15135
gene id: 47917:WN53_RS15135
uniprot id: A0A0F7HC06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
messages: Binds 1 Fe cation.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
messages: This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD).

47917:WN53 RS18230
gene id: 47917:WN53_RS18230
uniprot id: A0A0F7HHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

47917:WN53 RS11740
gene id: 47917:WN53_RS11740
uniprot id: A0A0F7D1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

47917:WN53 RS13340
gene id: 47917:WN53_RS13340
uniprot id: A0A1Q5V7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

47917:WN53 RS07530
gene id: 47917:WN53_RS07530
uniprot id: A0A0F7H8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS01675
gene id: 47917:WN53_RS01675
uniprot id: A0A0F7H7L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

47917:WN53 RS14380
gene id: 47917:WN53_RS14380
uniprot id: A0A0F7HCI7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

47917:WN53 RS24035
gene id: 47917:WN53_RS24035
uniprot id: A0A0F7HF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

47917:WN53 RS25905
gene id: 47917:WN53_RS25905
uniprot id: A0A0F7HFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS10980
gene id: 47917:WN53_RS10980
uniprot id: A0A0F7HB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

47917:WN53 RS04145
gene id: 47917:WN53_RS04145
uniprot id: A0A0F7D150
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

47917:WN53 RS14525
gene id: 47917:WN53_RS14525
uniprot id: A0A0F7HBL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

47917:WN53 RS23595
gene id: 47917:WN53_RS23595
uniprot id: A0A0F7HGD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

47917:WN53 RS12135
gene id: 47917:WN53_RS12135
uniprot id: A0A0F7HAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS00460
gene id: 47917:WN53_RS00460
uniprot id: A0A0F7H635
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS19760
gene id: 47917:WN53_RS19760
uniprot id: A0A0F7D2R2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

47917:WN53 RS04715
gene id: 47917:WN53_RS04715
uniprot id: A0A0F7H8U2
names: Similarity
messages: Belongs to the peptidase S1C family.

47917:WN53 RS18030
gene id: 47917:WN53_RS18030
uniprot id: A0A0F7D2K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

47917:WN53 RS23940
gene id: 47917:WN53_RS23940
uniprot id: A0A3S5AX28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

47917:WN53 RS10350
gene id: 47917:WN53_RS10350
uniprot id: A0A0F7HA14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

47917:WN53 RS20885
gene id: 47917:WN53_RS20885
uniprot id: A0A0F7HE39
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS02485
gene id: 47917:WN53_RS02485
uniprot id: A0A0F7H7W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS24605
gene id: 47917:WN53_RS24605
uniprot id: A0A0F7HGQ8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00735
gene id: 47917:WN53_RS00735
uniprot id: A0A0F7H745
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

47917:WN53 RS15835
gene id: 47917:WN53_RS15835
uniprot id: A0A0F7HHC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

47917:WN53 RS10825
gene id: 47917:WN53_RS10825
uniprot id: A0A0F7HBA9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS21905
gene id: 47917:WN53_RS21905
uniprot id: A0A0F7HFR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS02735
gene id: 47917:WN53_RS02735
uniprot id: A0A0F7H806
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS15140
gene id: 47917:WN53_RS15140
uniprot id: A0A0F7HBT9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

47917:WN53 RS17695
gene id: 47917:WN53_RS17695
uniprot id: A0A0F7HE09
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

47917:WN53 RS13600
gene id: 47917:WN53_RS13600
uniprot id: A0A0F7HCC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

47917:WN53 RS20900
gene id: 47917:WN53_RS20900
uniprot id: A0A0F7D2V3
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS11930
gene id: 47917:WN53_RS11930
uniprot id: A0A0F7HBH7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

47917:WN53 RS24715
gene id: 47917:WN53_RS24715
uniprot id: A0A0F7HFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS01760
gene id: 47917:WN53_RS01760
uniprot id: A0A0F7H6Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

47917:WN53 RS23605
gene id: 47917:WN53_RS23605
uniprot id: A0A0F7HH28
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS09235
gene id: 47917:WN53_RS09235
uniprot id: A0A0F7H9F4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS06085
gene id: 47917:WN53_RS06085
uniprot id: A0A0F7H856
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS16445
gene id: 47917:WN53_RS16445
uniprot id: A0A0F7HCA8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

47917:WN53 RS23815
gene id: 47917:WN53_RS23815
uniprot id: A0A0F7D357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

47917:WN53 RS06445
gene id: 47917:WN53_RS06445
uniprot id: A0A0F7H9B6
names: Similarity
messages: Belongs to the TPP enzyme family.

47917:WN53 RS17235
gene id: 47917:WN53_RS17235
uniprot id: A0A0F7HCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

47917:WN53 RS00760
gene id: 47917:WN53_RS00760
uniprot id: A0A0F7H785
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

47917:WN53 RS19790
gene id: 47917:WN53_RS19790
uniprot id: A0A0F7HF18
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00740
gene id: 47917:WN53_RS00740
uniprot id: A0A0F7H7I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

47917:WN53 RS02385
gene id: 47917:WN53_RS02385
uniprot id: A0A0F7D0Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

47917:WN53 RS03020
gene id: 47917:WN53_RS03020
uniprot id: A0A0F7H852
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

47917:WN53 RS06250
gene id: 47917:WN53_RS06250
uniprot id: A0A0F7H9R1
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS10470
gene id: 47917:WN53_RS10470
uniprot id: A0A0F7D1S5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS18035
gene id: 47917:WN53_RS18035
uniprot id: A0A0F7HET2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

47917:WN53 RS10300
gene id: 47917:WN53_RS10300
uniprot id: A0A0F7HB51
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

47917:WN53 RS20185
gene id: 47917:WN53_RS20185
uniprot id: A0A0F7HFW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

47917:WN53 RS20605
gene id: 47917:WN53_RS20605
uniprot id: A0A0F7HI71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

47917:WN53 RS04450
gene id: 47917:WN53_RS04450
uniprot id: A0A0F7H7H0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

47917:WN53 RS22675
gene id: 47917:WN53_RS22675
uniprot id: A0A0F7HF51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

47917:WN53 RS17335
gene id: 47917:WN53_RS17335
uniprot id: A0A0F7D2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

47917:WN53 RS09185
gene id: 47917:WN53_RS09185
uniprot id: A0A0F7HB02
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

47917:WN53 RS24250
gene id: 47917:WN53_RS24250
uniprot id: A0A0F7HFN7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

47917:WN53 RS10215
gene id: 47917:WN53_RS10215
uniprot id: A0A0F7H9T6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

47917:WN53 RS00770
gene id: 47917:WN53_RS00770
uniprot id: A0A0F7H7I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

47917:WN53 RS22200
gene id: 47917:WN53_RS22200
uniprot id: A0A0F7HFX4
names: Similarity
messages: Belongs to the UPF0263 family.

47917:WN53 RS00705
gene id: 47917:WN53_RS00705
uniprot id: A0A0F7D0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

47917:WN53 RS23400
gene id: 47917:WN53_RS23400
uniprot id: A0A0F7D342
names: Similarity
messages: Belongs to the UPF0053 family.

47917:WN53 RS25865
gene id: 47917:WN53_RS25865
uniprot id: A0A0F7HI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

47917:WN53 RS05415
gene id: 47917:WN53_RS05415
uniprot id: A0A0F7H7V5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

47917:WN53 RS04380
gene id: 47917:WN53_RS04380
uniprot id: A0A0F7D159
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

47917:WN53 RS12100
gene id: 47917:WN53_RS12100
uniprot id: A0A0F7HAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

47917:WN53 RS02570
gene id: 47917:WN53_RS02570
uniprot id: A0A0F7H7Q3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

47917:WN53 RS08055
gene id: 47917:WN53_RS08055
uniprot id: A0A0F7D1J3
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

47917:WN53 RS00290
gene id: 47917:WN53_RS00290
uniprot id: A0A0F7D0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

47917:WN53 RS05005
gene id: 47917:WN53_RS05005
uniprot id: A0A0F7H8S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

47917:WN53 RS00680
gene id: 47917:WN53_RS00680
uniprot id: A0A0F7D3G0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07130
gene id: 47917:WN53_RS07130
uniprot id: A0A0F7H8J6
names: Subcellular Location Annotation
messages: Cell inner membrane

47917:WN53 RS18465
gene id: 47917:WN53_RS18465
uniprot id: A0A0F7D2L5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22710
gene id: 47917:WN53_RS22710
uniprot id: A0A0F7HF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

47917:WN53 RS04990
gene id: 47917:WN53_RS04990
uniprot id: A0A0F7H8W4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS14510
gene id: 47917:WN53_RS14510
uniprot id: A0A0F7HCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

47917:WN53 RS12645
gene id: 47917:WN53_RS12645
uniprot id: A0A0F7HAU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

47917:WN53 RS07215
gene id: 47917:WN53_RS07215
uniprot id: A0A0F7H8U8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

47917:WN53 RS05145
gene id: 47917:WN53_RS05145
uniprot id: A0A0F7H9A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

47917:WN53 RS12590
gene id: 47917:WN53_RS12590
uniprot id: A0A0F7D202
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04935
gene id: 47917:WN53_RS04935
uniprot id: A0A0F7H8R8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

47917:WN53 RS08145
gene id: 47917:WN53_RS08145
uniprot id: A0A0F7H924
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

47917:WN53 RS14540
gene id: 47917:WN53_RS14540
uniprot id: A0A0F7HCK7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

47917:WN53 RS00750
gene id: 47917:WN53_RS00750
uniprot id: A0A0F7H607
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

47917:WN53 RS23870
gene id: 47917:WN53_RS23870
uniprot id: A0A0F7D359
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS14330
gene id: 47917:WN53_RS14330
uniprot id: A0A0F7HBJ6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

47917:WN53 RS20500
gene id: 47917:WN53_RS20500
uniprot id: A0A0F7D2T9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS16060
gene id: 47917:WN53_RS16060
uniprot id: A0A0F7HDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

47917:WN53 RS19360
gene id: 47917:WN53_RS19360
uniprot id: A0A0F7HDL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS14565
gene id: 47917:WN53_RS14565
uniprot id: A0A0F7HCM8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

47917:WN53 RS22785
gene id: 47917:WN53_RS22785
uniprot id: A0A0F7D322
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

47917:WN53 RS19355
gene id: 47917:WN53_RS19355
uniprot id: A0A0F7HFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

47917:WN53 RS12305
gene id: 47917:WN53_RS12305
uniprot id: A0A0F7HCE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS06630
gene id: 47917:WN53_RS06630
uniprot id: A0A0F7H8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS17975
gene id: 47917:WN53_RS17975
uniprot id: A0A0F7HD01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

47917:WN53 RS07775
gene id: 47917:WN53_RS07775
uniprot id: A0A0F7HAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

47917:WN53 RS23065
gene id: 47917:WN53_RS23065
uniprot id: A0A0F7D331
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24565
gene id: 47917:WN53_RS24565
uniprot id: A0A0F7HFT3
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS20030
gene id: 47917:WN53_RS20030
uniprot id: A0A0F7HF49
names: Similarity
messages: Belongs to the glutathione peroxidase family.

47917:WN53 RS01610
gene id: 47917:WN53_RS01610
uniprot id: A0A0F7H6D2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

47917:WN53 RS11005
gene id: 47917:WN53_RS11005
uniprot id: A0A0F7HBC8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00395
gene id: 47917:WN53_RS00395
uniprot id: A0A0F7D0S0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

47917:WN53 RS10335
gene id: 47917:WN53_RS10335
uniprot id: A0A0F7HAR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

47917:WN53 RS23855
gene id: 47917:WN53_RS23855
uniprot id: A0A0F7HGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

47917:WN53 RS15270
gene id: 47917:WN53_RS15270
uniprot id: A0A0F7D298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

47917:WN53 RS01750
gene id: 47917:WN53_RS01750
uniprot id: A0A0F7H7X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

47917:WN53 RS04350
gene id: 47917:WN53_RS04350
uniprot id: A0A0F7H7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

47917:WN53 RS27210
gene id: 47917:WN53_RS27210
uniprot id: A0A1Q5V8G0
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

47917:WN53 RS25450
gene id: 47917:WN53_RS25450
uniprot id: A0A0F7D3B5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

47917:WN53 RS16005
gene id: 47917:WN53_RS16005
uniprot id: A0A0F7HD34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS10700
gene id: 47917:WN53_RS10700
uniprot id: A0A0F7HAX2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS13010
gene id: 47917:WN53_RS13010
uniprot id: A0A0F7HAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS10095
gene id: 47917:WN53_RS10095
uniprot id: A0A0F7HBC5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS09875
gene id: 47917:WN53_RS09875
uniprot id: A0A0F7H9W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

47917:WN53 RS07720
gene id: 47917:WN53_RS07720
uniprot id: A0A448TC59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

47917:WN53 RS20160
gene id: 47917:WN53_RS20160
uniprot id: A0A0F7HDT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS05225
gene id: 47917:WN53_RS05225
uniprot id: A0A0F7H8Z4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

47917:WN53 RS22270
gene id: 47917:WN53_RS22270
uniprot id: A0A0F7HFY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS13940
gene id: 47917:WN53_RS13940
uniprot id: A0A0F7HB97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS11760
gene id: 47917:WN53_RS11760
uniprot id: A0A0F7HBQ4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

47917:WN53 RS05265
gene id: 47917:WN53_RS05265
uniprot id: A0A0F7H8Z7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

47917:WN53 RS08990
gene id: 47917:WN53_RS08990
uniprot id: A0A0F7HAM9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS17690
gene id: 47917:WN53_RS17690
uniprot id: A0A0F7D2I8
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07730
gene id: 47917:WN53_RS07730
uniprot id: A0A0F7HA78
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

47917:WN53 RS24515
gene id: 47917:WN53_RS24515
uniprot id: A0A0F7HHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

47917:WN53 RS16120
gene id: 47917:WN53_RS16120
uniprot id: A0A0F7HC65
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22295
gene id: 47917:WN53_RS22295
uniprot id: A0A0F7D304
names: Similarity
messages: Belongs to the LOG family.

47917:WN53 RS09515
gene id: 47917:WN53_RS09515
uniprot id: A0A0F7H9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

47917:WN53 RS06170
gene id: 47917:WN53_RS06170
uniprot id: A0A0F7D1C6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

47917:WN53 RS07060
gene id: 47917:WN53_RS07060
uniprot id: A0A0F7H8I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

47917:WN53 RS02670
gene id: 47917:WN53_RS02670
uniprot id: A0A0F7D101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

47917:WN53 RS21935
gene id: 47917:WN53_RS21935
uniprot id: A0A0F7HFV1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

47917:WN53 RS14505
gene id: 47917:WN53_RS14505
uniprot id: A0A0F7HCM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS24385
gene id: 47917:WN53_RS24385
uniprot id: A0A0F7D378
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

47917:WN53 RS02150
gene id: 47917:WN53_RS02150
uniprot id: A0A0F7H832
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS05795
gene id: 47917:WN53_RS05795
uniprot id: A0A0F7H9J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

47917:WN53 RS12030
gene id: 47917:WN53_RS12030
uniprot id: A0A0F7HCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

47917:WN53 RS14430
gene id: 47917:WN53_RS14430
uniprot id: A0A0F7HBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS06330
gene id: 47917:WN53_RS06330
uniprot id: A0A0F7H894
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

47917:WN53 RS13750
gene id: 47917:WN53_RS13750
uniprot id: A0A0F7HD27
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS16915
gene id: 47917:WN53_RS16915
uniprot id: A0A0F7HCK5
names: Similarity
messages: Belongs to the GST superfamily.

47917:WN53 RS19255
gene id: 47917:WN53_RS19255
uniprot id: A0A0F7HDI4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15380
gene id: 47917:WN53_RS15380
uniprot id: A0A0F7D2A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

47917:WN53 RS13590
gene id: 47917:WN53_RS13590
uniprot id: A0A0F7HBB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

47917:WN53 RS06400
gene id: 47917:WN53_RS06400
uniprot id: A0A0F7H8A2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS04920
gene id: 47917:WN53_RS04920
uniprot id: A0A0F7D179
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

47917:WN53 RS13180
gene id: 47917:WN53_RS13180
uniprot id: A0A0F7HC18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

47917:WN53 RS00200
gene id: 47917:WN53_RS00200
uniprot id: A0A0F7H6Y5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07320
gene id: 47917:WN53_RS07320
uniprot id: A0A0F7D1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

47917:WN53 RS06175
gene id: 47917:WN53_RS06175
uniprot id: A0A0F7H9P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

47917:WN53 RS25120
gene id: 47917:WN53_RS25120
uniprot id: A0A0F7D3A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS17430
gene id: 47917:WN53_RS17430
uniprot id: A0A0F7HCX5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

47917:WN53 RS20745
gene id: 47917:WN53_RS20745
uniprot id: A0A0F7HG32
names: Subcellular Location Annotation
messages: Cell outer membrane

47917:WN53 RS06235
gene id: 47917:WN53_RS06235
uniprot id: A0A0F7H9D9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

47917:WN53 RS02745
gene id: 47917:WN53_RS02745
uniprot id: A0A0F7H8B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

47917:WN53 RS25885
gene id: 47917:WN53_RS25885
uniprot id: A0A0F7HHB4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS05150
gene id: 47917:WN53_RS05150
uniprot id: A0A0F7H834
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

47917:WN53 RS24600
gene id: 47917:WN53_RS24600
uniprot id: A0A0F7HFT9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS23860
gene id: 47917:WN53_RS23860
uniprot id: A0A0F7HH46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

47917:WN53 RS05675
gene id: 47917:WN53_RS05675
uniprot id: A0A0F7H7Y9
names: Similarity
messages: Belongs to the Smg family.

47917:WN53 RS14190
gene id: 47917:WN53_RS14190
uniprot id: A0A0F7D257
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

47917:WN53 RS13085
gene id: 47917:WN53_RS13085
uniprot id: A0A0F7HC63
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS15960
gene id: 47917:WN53_RS15960
uniprot id: A0A0F7HC38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

47917:WN53 RS07560
gene id: 47917:WN53_RS07560
uniprot id: A0A0F7H8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

47917:WN53 RS01935
gene id: 47917:WN53_RS01935
uniprot id: A0A0F7HHN6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS22855
gene id: 47917:WN53_RS22855
uniprot id: A0A0F7HET9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.

47917:WN53 RS22160
gene id: 47917:WN53_RS22160
uniprot id: A0A0F7D2Z9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

47917:WN53 RS06770
gene id: 47917:WN53_RS06770
uniprot id: A0A0F7HHV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS14020
gene id: 47917:WN53_RS14020
uniprot id: A0A0F7HCF5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS21705
gene id: 47917:WN53_RS21705
uniprot id: A0A0F7HGJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS25620
gene id: 47917:WN53_RS25620
uniprot id: A0A0F7HGX6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

47917:WN53 RS08110
gene id: 47917:WN53_RS08110
uniprot id: A0A0F7H9A6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS01390
gene id: 47917:WN53_RS01390
uniprot id: A0A0F7H6A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

47917:WN53 RS07015
gene id: 47917:WN53_RS07015
uniprot id: A0A0F7D1F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

47917:WN53 RS02755
gene id: 47917:WN53_RS02755
uniprot id: A0A0F7D104
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

47917:WN53 RS15545
gene id: 47917:WN53_RS15545
uniprot id: A0A0F7HCU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

47917:WN53 RS05590
gene id: 47917:WN53_RS05590
uniprot id: A0A0F7H941
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

47917:WN53 RS01490
gene id: 47917:WN53_RS01490
uniprot id: A0A0F7H7I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS15100
gene id: 47917:WN53_RS15100
uniprot id: A0A0F7HDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

47917:WN53 RS25810
gene id: 47917:WN53_RS25810
uniprot id: A0A0F7HHB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS25535
gene id: 47917:WN53_RS25535
uniprot id: A0A0F7HH80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

47917:WN53 RS19985
gene id: 47917:WN53_RS19985
uniprot id: A0A0F7HHY0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

47917:WN53 RS05780
gene id: 47917:WN53_RS05780
uniprot id: A0A0F7H967
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

47917:WN53 RS25425
gene id: 47917:WN53_RS25425
uniprot id: A0A0F7HGA1
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS24950
gene id: 47917:WN53_RS24950
uniprot id: A0A0F7HG13
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

47917:WN53 RS16615
gene id: 47917:WN53_RS16615
uniprot id: A0A0F7D2E7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS07085
gene id: 47917:WN53_RS07085
uniprot id: A0A0F7H8T2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

47917:WN53 RS26215
gene id: 47917:WN53_RS26215
uniprot id: A0A0F7HHK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

47917:WN53 RS04385
gene id: 47917:WN53_RS04385
uniprot id: A0A0F7H7G3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

47917:WN53 RS10950
gene id: 47917:WN53_RS10950
uniprot id: A0A0F7HA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS15680
gene id: 47917:WN53_RS15680
uniprot id: A0A0F7HCY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

47917:WN53 RS15775
gene id: 47917:WN53_RS15775
uniprot id: A0A0F7HD66
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

47917:WN53 RS07205
gene id: 47917:WN53_RS07205
uniprot id: A0A0F7H9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

47917:WN53 RS05090
gene id: 47917:WN53_RS05090
uniprot id: A0A0F7H8X5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

47917:WN53 RS05380
gene id: 47917:WN53_RS05380
uniprot id: A0A0F7H864
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

47917:WN53 RS01695
gene id: 47917:WN53_RS01695
uniprot id: A0A0F7H6P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

47917:WN53 RS11540
gene id: 47917:WN53_RS11540
uniprot id: A0A0F7HBP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS02550
gene id: 47917:WN53_RS02550
uniprot id: A0A0F7H713
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

47917:WN53 RS19305
gene id: 47917:WN53_RS19305
uniprot id: A0A0F7HDS5
names: Similarity
messages: Belongs to the UPF0227 family.

47917:WN53 RS14940
gene id: 47917:WN53_RS14940
uniprot id: A0A0F7HBS4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS25220
gene id: 47917:WN53_RS25220
uniprot id: A0A0F7HH83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

47917:WN53 RS13230
gene id: 47917:WN53_RS13230
uniprot id: A0A0F7HB12
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

47917:WN53 RS10715
gene id: 47917:WN53_RS10715
uniprot id: A0A0F7D1T4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

47917:WN53 RS24040
gene id: 47917:WN53_RS24040
uniprot id: A0A0F7HFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS01595
gene id: 47917:WN53_RS01595
uniprot id: A0A0F7H6N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS25650
gene id: 47917:WN53_RS25650
uniprot id: A0A0F7HHC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS10195
gene id: 47917:WN53_RS10195
uniprot id: A0A0F7HAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS20045
gene id: 47917:WN53_RS20045
uniprot id: A0A0F7HFU9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

47917:WN53 RS16605
gene id: 47917:WN53_RS16605
uniprot id: A0A0F7HCD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

47917:WN53 RS05185
gene id: 47917:WN53_RS05185
uniprot id: A0A0F7D189
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

47917:WN53 RS14375
gene id: 47917:WN53_RS14375
uniprot id: A0A0F7HCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS16600
gene id: 47917:WN53_RS16600
uniprot id: A0A0F7HCJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

47917:WN53 RS01000
gene id: 47917:WN53_RS01000
uniprot id: A0A0F7D0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

47917:WN53 RS06520
gene id: 47917:WN53_RS06520
uniprot id: A0A0F7H9U7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

47917:WN53 RS18880
gene id: 47917:WN53_RS18880
uniprot id: A0A0F7HDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

47917:WN53 RS01735
gene id: 47917:WN53_RS01735
uniprot id: A0A0F7H6F4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS06240
gene id: 47917:WN53_RS06240
uniprot id: A0A0F7H984
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

47917:WN53 RS07830
gene id: 47917:WN53_RS07830
uniprot id: A0A0F7HA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS01930
gene id: 47917:WN53_RS01930
uniprot id: A0A0F7H6H7
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS25455
gene id: 47917:WN53_RS25455
uniprot id: A0A0F7HFR2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

47917:WN53 RS14200
gene id: 47917:WN53_RS14200
uniprot id: A0A0F7HDA5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

47917:WN53 RS14225
gene id: 47917:WN53_RS14225
uniprot id: A0A0F7HCH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS15990
gene id: 47917:WN53_RS15990
uniprot id: A0A0F7HC43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

47917:WN53 RS15875
gene id: 47917:WN53_RS15875
uniprot id: A0A0F7HD74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

47917:WN53 RS00825
gene id: 47917:WN53_RS00825
uniprot id: A0A0F7H617
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

47917:WN53 RS02170
gene id: 47917:WN53_RS02170
uniprot id: A0A0F7H7S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

47917:WN53 RS16655
gene id: 47917:WN53_RS16655
uniprot id: A0A0F7HEF2
names: Function
messages: Required for maximal bacterial cellulose synthesis.

47917:WN53 RS20565
gene id: 47917:WN53_RS20565
uniprot id: A0A0F7D2U1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS02960
gene id: 47917:WN53_RS02960
uniprot id: A0A0F7D112
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

47917:WN53 RS01425
gene id: 47917:WN53_RS01425
uniprot id: A0A0F7D0V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

47917:WN53 RS25230
gene id: 47917:WN53_RS25230
uniprot id: A0A0F7HFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

47917:WN53 RS13635
gene id: 47917:WN53_RS13635
uniprot id: A0A0F7D237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

47917:WN53 RS13580
gene id: 47917:WN53_RS13580
uniprot id: A0A0F7HD17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

47917:WN53 RS00445
gene id: 47917:WN53_RS00445
uniprot id: A0A0F7D0S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

47917:WN53 RS01960
gene id: 47917:WN53_RS01960
uniprot id: A0A0F7H6S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

47917:WN53 RS09135
gene id: 47917:WN53_RS09135
uniprot id: A0A0F7D1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS04130
gene id: 47917:WN53_RS04130
uniprot id: A0A0F7H8I4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS21130
gene id: 47917:WN53_RS21130
uniprot id: A0A0F7HEE5
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS00270
gene id: 47917:WN53_RS00270
uniprot id: A0A0F7H602
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

47917:WN53 RS10355
gene id: 47917:WN53_RS10355
uniprot id: A0A0F7H9V6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

47917:WN53 RS07750
gene id: 47917:WN53_RS07750
uniprot id: A0A0F7H956
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

47917:WN53 RS01755
gene id: 47917:WN53_RS01755
uniprot id: A0A0F7D0X0
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

47917:WN53 RS05885
gene id: 47917:WN53_RS05885
uniprot id: A0A0F7H9K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

47917:WN53 RS11220
gene id: 47917:WN53_RS11220
uniprot id: A0A0F7HB71
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

47917:WN53 RS25675
gene id: 47917:WN53_RS25675
uniprot id: A0A0F7HH98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

47917:WN53 RS20890
gene id: 47917:WN53_RS20890
uniprot id: A0A0F7HEB4
names: Similarity
messages: Belongs to the aspartokinase family.

47917:WN53 RS09570
gene id: 47917:WN53_RS09570
uniprot id: A0A0F7HB48
names: Similarity
messages: Belongs to the ABC transporter superfamily.

47917:WN53 RS01980
gene id: 47917:WN53_RS01980
uniprot id: A0A0F7H7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

47917:WN53 RS20440
gene id: 47917:WN53_RS20440
uniprot id: A0A0F7HF97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

47917:WN53 RS17260
gene id: 47917:WN53_RS17260
uniprot id: A0A0F7HEL2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

47917:WN53 RS22485
gene id: 47917:WN53_RS22485
uniprot id: A0A0F7HEQ2
names: Similarity
messages: Belongs to the universal stress protein A family.

47917:WN53 RS25500
gene id: 47917:WN53_RS25500
uniprot id: A0A0F7HH76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

47917:WN53 RS13225
gene id: 47917:WN53_RS13225
uniprot id: A0A0F7HB94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

47917:WN53 RS05175
gene id: 47917:WN53_RS05175
uniprot id: A0A0F7H9A5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

47917:WN53 RS19295
gene id: 47917:WN53_RS19295
uniprot id: A0A0F7D2P5
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

47917:WN53 RS00110
gene id: 47917:WN53_RS00110
uniprot id: A0A0F7H781
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS22925
gene id: 47917:WN53_RS22925
uniprot id: A0A0F7HGZ9
names: Similarity
messages: Belongs to the UPF0303 family.

47917:WN53 RS14195
gene id: 47917:WN53_RS14195
uniprot id: A0A0F7HCG5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

47917:WN53 RS25035
gene id: 47917:WN53_RS25035
uniprot id: A0A0F7HH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

47917:WN53 RS21755
gene id: 47917:WN53_RS21755
uniprot id: A0A0F7HEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS18875
gene id: 47917:WN53_RS18875
uniprot id: A0A0F7D2N0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

47917:WN53 RS25630
gene id: 47917:WN53_RS25630
uniprot id: A0A0F7HFT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS10625
gene id: 47917:WN53_RS10625
uniprot id: A0A0F7H9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

47917:WN53 RS25065
gene id: 47917:WN53_RS25065
uniprot id: A0A0F7HH39
names: Similarity
messages: Belongs to the elongation factor P family.

47917:WN53 RS20515
gene id: 47917:WN53_RS20515
uniprot id: A0A0F7HF22
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

47917:WN53 RS09240
gene id: 47917:WN53_RS09240
uniprot id: A0A0F7HAQ6
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

47917:WN53 RS25655
gene id: 47917:WN53_RS25655
uniprot id: A0A0F7HI47
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS13885
gene id: 47917:WN53_RS13885
uniprot id: A0A0F7HGM8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

47917:WN53 RS18860
gene id: 47917:WN53_RS18860
uniprot id: A0A0F7HEH9
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

47917:WN53 RS19915
gene id: 47917:WN53_RS19915
uniprot id: A0A0F7HDZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

47917:WN53 RS10785
gene id: 47917:WN53_RS10785
uniprot id: A0A0F7HA06
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

47917:WN53 RS09465
gene id: 47917:WN53_RS09465
uniprot id: A0A0F7HB40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

47917:WN53 RS11135
gene id: 47917:WN53_RS11135
uniprot id: A0A0F7HA43
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

47917:WN53 RS02395
gene id: 47917:WN53_RS02395
uniprot id: A0A0F7H6Z6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

47917:WN53 RS10150
gene id: 47917:WN53_RS10150
uniprot id: A0A0F7D1R3
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

47917:WN53 RS15750
gene id: 47917:WN53_RS15750
uniprot id: A0A0F7HCZ5
names: Similarity
messages: Belongs to the citrate synthase family.

47917:WN53 RS11560
gene id: 47917:WN53_RS11560
uniprot id: A0A0F7D1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

47917:WN53 RS12640
gene id: 47917:WN53_RS12640
uniprot id: A0A0F7D204
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

47917:WN53 RS00975
gene id: 47917:WN53_RS00975
uniprot id: A0A0F7D0U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

47917:WN53 RS13235
gene id: 47917:WN53_RS13235
uniprot id: A0A0F7D223
names: Subcellular Location Annotation
messages: Cytoplasm

47917:WN53 RS23315
gene id: 47917:WN53_RS23315
uniprot id: A0A0F7HH15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Periplasm

47917:WN53 RS21820
gene id: 47917:WN53_RS21820
uniprot id: A0A0F7HEV2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS06280
gene id: 47917:WN53_RS06280
uniprot id: A0A0F7H9R6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

47917:WN53 RS15815
gene id: 47917:WN53_RS15815
uniprot id: A0A0F7HD00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

47917:WN53 RS03050
gene id: 47917:WN53_RS03050
uniprot id: A0A0F7HHP4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

47917:WN53 RS20485
gene id: 47917:WN53_RS20485
uniprot id: A0A0F7HF17
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

47917:WN53 RS09520
gene id: 47917:WN53_RS09520
uniprot id: A0A0F7H9J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

47917:WN53 RS14365
gene id: 47917:WN53_RS14365
uniprot id: A0A0F7D264
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS09555
gene id: 47917:WN53_RS09555
uniprot id: A0A0F7D1P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS11715
gene id: 47917:WN53_RS11715
uniprot id: A0A0F7D1X0
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

47917:WN53 RS09800
gene id: 47917:WN53_RS09800
uniprot id: A0A0F7HB74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

47917:WN53 RS08930
gene id: 47917:WN53_RS08930
uniprot id: A0A0F7HAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

47917:WN53 RS02765
gene id: 47917:WN53_RS02765
uniprot id: A0A0F7H811
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS23415
gene id: 47917:WN53_RS23415
uniprot id: A0A0F7HEZ9
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS03745
gene id: 47917:WN53_RS03745
uniprot id: A0A0F7H875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS25570
gene id: 47917:WN53_RS25570
uniprot id: A0A0F7HGE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS19230
gene id: 47917:WN53_RS19230
uniprot id: A0A0F7HDR6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS06335
gene id: 47917:WN53_RS06335
uniprot id: A0A0F7H9F0
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

47917:WN53 RS11595
gene id: 47917:WN53_RS11595
uniprot id: A0A0F7HHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

47917:WN53 RS24615
gene id: 47917:WN53_RS24615
uniprot id: A0A0F7D386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS10705
gene id: 47917:WN53_RS10705
uniprot id: A0A0F7HBK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

47917:WN53 RS13070
gene id: 47917:WN53_RS13070
uniprot id: A0A0F7HB75
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

47917:WN53 RS17175
gene id: 47917:WN53_RS17175
uniprot id: A0A0F7HCU7
names: Similarity
messages: Belongs to the UPF0053 family.

47917:WN53 RS22060
gene id: 47917:WN53_RS22060
uniprot id: A0A0F7HEX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

47917:WN53 RS09665
gene id: 47917:WN53_RS09665
uniprot id: A0A0F7HB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

47917:WN53 RS25300
gene id: 47917:WN53_RS25300
uniprot id: A0A0F7D3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS10720
gene id: 47917:WN53_RS10720
uniprot id: A0A0F7H9Z9
names: Similarity
messages: Belongs to the UPF0306 family.

47917:WN53 RS16435
gene id: 47917:WN53_RS16435
uniprot id: A0A0F7D2E0
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS04120
gene id: 47917:WN53_RS04120
uniprot id: A0A0F7D149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

47917:WN53 RS17040
gene id: 47917:WN53_RS17040
uniprot id: A0A0F7HEJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

47917:WN53 RS18285
gene id: 47917:WN53_RS18285
uniprot id: A0A0F7HDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

47917:WN53 RS15645
gene id: 47917:WN53_RS15645
uniprot id: A0A0F7D2B1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

47917:WN53 RS04040
gene id: 47917:WN53_RS04040
uniprot id: A0A0F7H7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS15760
gene id: 47917:WN53_RS15760
uniprot id: A0A0F7D2B5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

47917:WN53 RS17050
gene id: 47917:WN53_RS17050
uniprot id: A0A0F7HCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS02175
gene id: 47917:WN53_RS02175
uniprot id: A0A0F7H7K7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

47917:WN53 RS07430
gene id: 47917:WN53_RS07430
uniprot id: A0A0F7H9V0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS12025
gene id: 47917:WN53_RS12025
uniprot id: A0A0F7HBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

47917:WN53 RS01705
gene id: 47917:WN53_RS01705
uniprot id: A0A0F7D0W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

47917:WN53 RS01030
gene id: 47917:WN53_RS01030
uniprot id: A0A0F7H7C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

47917:WN53 RS05520
gene id: 47917:WN53_RS05520
uniprot id: A0A0F7D1A2
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS20700
gene id: 47917:WN53_RS20700
uniprot id: A0A0F7HFC6
names: Similarity
messages: Belongs to the AHA1 family.

47917:WN53 RS20055
gene id: 47917:WN53_RS20055
uniprot id: A0A0F7HE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

47917:WN53 RS08170
gene id: 47917:WN53_RS08170
uniprot id: A0A0F7H9B4
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

47917:WN53 RS26155
gene id: 47917:WN53_RS26155
uniprot id: A0A292AF13
names: Similarity
messages: Belongs to the UPF0381 family.

47917:WN53 RS19225
gene id: 47917:WN53_RS19225
uniprot id: A0A0F7HDF1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

47917:WN53 RS04630
gene id: 47917:WN53_RS04630
uniprot id: A0A0F7H8N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

47917:WN53 RS16945
gene id: 47917:WN53_RS16945
uniprot id: A0A0F7D2F9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS12215
gene id: 47917:WN53_RS12215
uniprot id: A0A0F7HBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS00865
gene id: 47917:WN53_RS00865
uniprot id: A0A0F7D0T7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.

47917:WN53 RS15925
gene id: 47917:WN53_RS15925
uniprot id: A0A0F7HCA3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

47917:WN53 RS04395
gene id: 47917:WN53_RS04395
uniprot id: A0A0F7H8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

47917:WN53 RS18805
gene id: 47917:WN53_RS18805
uniprot id: A0A0F7HDB9
names: Similarity
messages: Belongs to the peptidase A31 family.

47917:WN53 RS18700
gene id: 47917:WN53_RS18700
uniprot id: A0A0F7HDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

47917:WN53 RS26415
gene id: 47917:WN53_RS26415
uniprot id: A0A0F7HGR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

47917:WN53 RS22465
gene id: 47917:WN53_RS22465
uniprot id: A0A0F7HG12
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

47917:WN53 RS15130
gene id: 47917:WN53_RS15130
uniprot id: A0A0F7HDV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS21805
gene id: 47917:WN53_RS21805
uniprot id: A0A0F7HGK9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

47917:WN53 RS20095
gene id: 47917:WN53_RS20095
uniprot id: A0A0F7HE19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

47917:WN53 RS05725
gene id: 47917:WN53_RS05725
uniprot id: A0A0F7H908
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

47917:WN53 RS17560
gene id: 47917:WN53_RS17560
uniprot id: A0A0F7HD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

47917:WN53 RS04585
gene id: 47917:WN53_RS04585
uniprot id: A0A0F7H7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS07840
gene id: 47917:WN53_RS07840
uniprot id: A0A0F7D1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

47917:WN53 RS15390
gene id: 47917:WN53_RS15390
uniprot id: A0A0F7HDY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

47917:WN53 RS00995
gene id: 47917:WN53_RS00995
uniprot id: A0A0F7H7B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

47917:WN53 RS10385
gene id: 47917:WN53_RS10385
uniprot id: A0A0F7H9V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

47917:WN53 RS07595
gene id: 47917:WN53_RS07595
uniprot id: A0A0F7H937
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

47917:WN53 RS27370
gene id: 47917:WN53_RS27370
uniprot id: A0A0F7HE63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

47917:WN53 RS12520
gene id: 47917:WN53_RS12520
uniprot id: A0A0F7HBU5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS08230
gene id: 47917:WN53_RS08230
uniprot id: A0A0F7D1K0
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

47917:WN53 RS07165
gene id: 47917:WN53_RS07165
uniprot id: A0A0F7H9S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

47917:WN53 RS06025
gene id: 47917:WN53_RS06025
uniprot id: A0A0F7H846
names: Similarity
messages: Belongs to the phosphoribulokinase family.

47917:WN53 RS22365
gene id: 47917:WN53_RS22365
uniprot id: A0A0F7HFZ7
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

47917:WN53 RS11780
gene id: 47917:WN53_RS11780
uniprot id: A0A0F7HAM7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

47917:WN53 RS17955
gene id: 47917:WN53_RS17955
uniprot id: A0A0F7D2J8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

47917:WN53 RS05125
gene id: 47917:WN53_RS05125
uniprot id: A0A0F7H7R4
names: Similarity
messages: Belongs to the peptidase U62 family.

47917:WN53 RS22650
gene id: 47917:WN53_RS22650
uniprot id: A0A0F7HIV0
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

47917:WN53 RS16585
gene id: 47917:WN53_RS16585
uniprot id: A0A0F7HD99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

47917:WN53 RS14725
gene id: 47917:WN53_RS14725
uniprot id: A0A0F7D278
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

47917:WN53 RS21875
gene id: 47917:WN53_RS21875
uniprot id: A0A0F7HFR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

47917:WN53 RS06145
gene id: 47917:WN53_RS06145
uniprot id: A0A0F7D1C5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

47917:WN53 RS17995
gene id: 47917:WN53_RS17995
uniprot id: A0A0F7HDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

47917:WN53 RS16855
gene id: 47917:WN53_RS16855
uniprot id: A0A0F7HDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

47917:WN53 RS04845
gene id: 47917:WN53_RS04845
uniprot id: A0A0F7D176
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS05435
gene id: 47917:WN53_RS05435
uniprot id: A0A0F7H9E4
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS08185
gene id: 47917:WN53_RS08185
uniprot id: A0A0F7HAD1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

47917:WN53 RS12145
gene id: 47917:WN53_RS12145
uniprot id: A0A0F7D1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

47917:WN53 RS14600
gene id: 47917:WN53_RS14600
uniprot id: A0A0F7HCN2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

47917:WN53 RS25420
gene id: 47917:WN53_RS25420
uniprot id: A0A0F7D3B4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

47917:WN53 RS27030
gene id: 47917:WN53_RS27030
uniprot id: A0A1Q5V9X6
names: Similarity
messages: Belongs to the UPF0253 family.

47917:WN53 RS17775
gene id: 47917:WN53_RS17775
uniprot id: A0A0F7HEP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS17670
gene id: 47917:WN53_RS17670
uniprot id: A0A0F7HDM9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

47917:WN53 RS16290
gene id: 47917:WN53_RS16290
uniprot id: A0A0F7HDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

47917:WN53 RS19910
gene id: 47917:WN53_RS19910
uniprot id: A0A0F7HDR2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

47917:WN53 RS11975
gene id: 47917:WN53_RS11975
uniprot id: A0A0F7HAQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

47917:WN53 RS21770
gene id: 47917:WN53_RS21770
uniprot id: A0A0F7HGK5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

47917:WN53 RS10510
gene id: 47917:WN53_RS10510
uniprot id: A0A0F7HA34
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

47917:WN53 RS11040
gene id: 47917:WN53_RS11040
uniprot id: A0A0F7HB24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

47917:WN53 RS18705
gene id: 47917:WN53_RS18705
uniprot id: A0A0F7D2M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

47917:WN53 RS22715
gene id: 47917:WN53_RS22715
uniprot id: A0A0F7HG45
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS22520
gene id: 47917:WN53_RS22520
uniprot id: A0A0F7HF34
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

47917:WN53 RS14655
gene id: 47917:WN53_RS14655
uniprot id: A0A0F7HBR4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

47917:WN53 RS25575
gene id: 47917:WN53_RS25575
uniprot id: A0A0F7HH84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

47917:WN53 RS14115
gene id: 47917:WN53_RS14115
uniprot id: A0A0F7HCH3
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

47917:WN53 RS13400
gene id: 47917:WN53_RS13400
uniprot id: A0A448S9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

47917:WN53 RS01915
gene id: 47917:WN53_RS01915
uniprot id: A0A0F7H7Z6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

47917:WN53 RS23575
gene id: 47917:WN53_RS23575
uniprot id: A0A0F7HF19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

47917:WN53 RS07210
gene id: 47917:WN53_RS07210
uniprot id: A0A0F7HA54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

47917:WN53 RS11980
gene id: 47917:WN53_RS11980
uniprot id: A0A0F7HAK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

47917:WN53 RS14180
gene id: 47917:WN53_RS14180
uniprot id: A0A0F7HBE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

47917:WN53 RS14140
gene id: 47917:WN53_RS14140
uniprot id: A0A0F7HBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

47917:WN53 RS19465
gene id: 47917:WN53_RS19465
uniprot id: A0A0F7HDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS26365
gene id: 47917:WN53_RS26365
uniprot id: A0A0F7HHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

47917:WN53 RS17265
gene id: 47917:WN53_RS17265
uniprot id: A0A0F7HCS9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

47917:WN53 RS20275
gene id: 47917:WN53_RS20275
uniprot id: A0A0F7HEY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

47917:WN53 RS03115
gene id: 47917:WN53_RS03115
uniprot id: A0A0F7H784
names: Similarity
messages: Belongs to the GSP E family.

47917:WN53 RS13670
gene id: 47917:WN53_RS13670
uniprot id: A0A0F7HC86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

47917:WN53 RS10595
gene id: 47917:WN53_RS10595
uniprot id: A0A3S4XBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

47917:WN53 RS16235
gene id: 47917:WN53_RS16235
uniprot id: A0A0F7HD56
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

47917:WN53 RS18665
gene id: 47917:WN53_RS18665
uniprot id: A0A0F7HDB5
names: Similarity
messages: Belongs to the carbamate kinase family.

47917:WN53 RS24570
gene id: 47917:WN53_RS24570
uniprot id: A0A0F7HGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

47917:WN53 RS18190
gene id: 47917:WN53_RS18190
uniprot id: A0A0F7D2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the invasin protein D family.
messages: Secreted

47917:WN53 RS06510
gene id: 47917:WN53_RS06510
uniprot id: A0A0F7H9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS18835
gene id: 47917:WN53_RS18835
uniprot id: A0A4U9THK2
names: Similarity
messages: Belongs to the HypE family.

47917:WN53 RS01380
gene id: 47917:WN53_RS01380
uniprot id: A0A0F7H6K3
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

47917:WN53 RS26210
gene id: 47917:WN53_RS26210
uniprot id: A0A0F7D3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

47917:WN53 RS17000
gene id: 47917:WN53_RS17000
uniprot id: A0A0F7HGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS05820
gene id: 47917:WN53_RS05820
uniprot id: A0A0F7H922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

47917:WN53 RS01355
gene id: 47917:WN53_RS01355
uniprot id: A0A0F7H695
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

47917:WN53 RS10760
gene id: 47917:WN53_RS10760
uniprot id: A0A0F7HBA5
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

47917:WN53 RS19220
gene id: 47917:WN53_RS19220
uniprot id: A0A0F7HFI5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

47917:WN53 RS10495
gene id: 47917:WN53_RS10495
uniprot id: A0A0F7D1S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

47917:WN53 RS11610
gene id: 47917:WN53_RS11610
uniprot id: A0A0F7HBE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

47917:WN53 RS12360
gene id: 47917:WN53_RS12360
uniprot id: A0A0F7HBR6
names: Subcellular Location Annotation
messages: Membrane

47917:WN53 RS26395
gene id: 47917:WN53_RS26395
uniprot id: A0A0F7HHL7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

47917:WN53 RS02965
gene id: 47917:WN53_RS02965
uniprot id: A0A0F7H7W6
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

47917:WN53 RS14275
gene id: 47917:WN53_RS14275
uniprot id: A0A0F7HBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

47917:WN53 RS15625
gene id: 47917:WN53_RS15625
uniprot id: A0A0F7HC70
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

47917:WN53 RS15395
gene id: 47917:WN53_RS15395
uniprot id: A0A0F7HC46
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

47917:WN53 RS21500
gene id: 47917:WN53_RS21500
uniprot id: A0A0F7HFL6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

47917:WN53 RS17735
gene id: 47917:WN53_RS17735
uniprot id: A0A0F7HDN8
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

47917:WN53 RS13520
gene id: 47917:WN53_RS13520
uniprot id: A0A0F7HD11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

47917:WN53 RS15355
gene id: 47917:WN53_RS15355
uniprot id: A0A0F7HI30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

47917:WN53 RS21185
gene id: 47917:WN53_RS21185
uniprot id: Q9RIR3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

47917:WN53 RS17005
gene id: 47917:WN53_RS17005
uniprot id: A0A0F7HEI9
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

47917:WN53 RS10945
gene id: 47917:WN53_RS10945
uniprot id: A0A0F7HBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

47917:WN53 RS10620
gene id: 47917:WN53_RS10620
uniprot id: A0A0F7HA48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

47917:WN53 RS05925
gene id: 47917:WN53_RS05925
uniprot id: A0A0F7H8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

47917:WN53 RS13900
gene id: 47917:WN53_RS13900
uniprot id: A0A0F7HD63
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

47917:WN53 RS17250
gene id: 47917:WN53_RS17250
uniprot id: A0A0F7HDJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

47917:WN53 RS03040
gene id: 47917:WN53_RS03040
uniprot id: A0A0F7H773
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

47917:WN53 RS01445
gene id: 47917:WN53_RS01445
uniprot id: A0A0F7H6L3
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.
messages: Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1-sulfonate (DHPS).

47917:WN53 RS11950
gene id: 47917:WN53_RS11950
uniprot id: A0A0F7HAK4
names: Caution
names: Function
messages: Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

47917:WN53 RS16160
gene id: 47917:WN53_RS16160
uniprot id: A0A0F7HC69
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

47917:WN53 RS21910
gene id: 47917:WN53_RS21910
uniprot id: A0A0F7HGM0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

47917:WN53 RS00455
gene id: 47917:WN53_RS00455
uniprot id: A0A0F7H7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS10310
gene id: 47917:WN53_RS10310
uniprot id: A0A0F7HBF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

47917:WN53 RS09395
gene id: 47917:WN53_RS09395
uniprot id: A0A0F7D1N7
names: Similarity
messages: Belongs to the Rht family.

47917:WN53 RS01680
gene id: 47917:WN53_RS01680
uniprot id: A0A0F7D0W7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

47917:WN53 RS01040
gene id: 47917:WN53_RS01040
uniprot id: A0A0F7H7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

47917:WN53 RS06955
gene id: 47917:WN53_RS06955
uniprot id: A0A0F7H9Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

47917:WN53 RS01790
gene id: 47917:WN53_RS01790
uniprot id: A0A0F7H6R4
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

47917:WN53 RS21830
gene id: 47917:WN53_RS21830
uniprot id: A0A0F7D2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

47917:WN53 RS24800
gene id: 47917:WN53_RS24800
uniprot id: A0A0F7HHJ5
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family.
messages: Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.

47917:WN53 RS16470
gene id: 47917:WN53_RS16470
uniprot id: A0A0F7HCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

47917:WN53 RS00695
gene id: 47917:WN53_RS00695
uniprot id: A0A0F7H775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

47917:WN53 RS24415
gene id: 47917:WN53_RS24415
uniprot id: A0A0F7HFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

47917:WN53 RS19040
gene id: 47917:WN53_RS19040
uniprot id: A0A0F7HDC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

47917:WN53 RS16050
gene id: 47917:WN53_RS16050
uniprot id: A0A0F7HCB9
names: Similarity
messages: Belongs to the MoaD family.

47917:WN53 RS12635
gene id: 47917:WN53_RS12635
uniprot id: A0A0F7HB00
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

47917:WN53 RS02035
gene id: 47917:WN53_RS02035
uniprot id: A0A0F7H6J5
names: Subcellular Location Annotation
messages: Membrane