472759:NHAL RS17310
gene id: 472759:NHAL_RS17310
uniprot id: D5C204
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

472759:NHAL RS01175
gene id: 472759:NHAL_RS01175
uniprot id: D5BUN8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

472759:NHAL RS02665
gene id: 472759:NHAL_RS02665
uniprot id: D5BW77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

472759:NHAL RS16665
gene id: 472759:NHAL_RS16665
uniprot id: D5C1B1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

472759:NHAL RS16490
gene id: 472759:NHAL_RS16490
uniprot id: D5C0V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

472759:NHAL RS13505
gene id: 472759:NHAL_RS13505
uniprot id: D5BXU1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

472759:NHAL RS11635
gene id: 472759:NHAL_RS11635
uniprot id: D5BVP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

472759:NHAL RS11520
gene id: 472759:NHAL_RS11520
uniprot id: D5BVA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

472759:NHAL RS00350
gene id: 472759:NHAL_RS00350
uniprot id: D5C4A1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS01350
gene id: 472759:NHAL_RS01350
uniprot id: D5BUS0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

472759:NHAL RS14315
gene id: 472759:NHAL_RS14315
uniprot id: D5BYM5
names: Similarity
messages: Belongs to the archease family.

472759:NHAL RS00725
gene id: 472759:NHAL_RS00725
uniprot id: D5C4T7
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS10420
gene id: 472759:NHAL_RS10420
uniprot id: D5C516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS11700
gene id: 472759:NHAL_RS11700
uniprot id: D5BVQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

472759:NHAL RS12335
gene id: 472759:NHAL_RS12335
uniprot id: D5BWG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

472759:NHAL RS12665
gene id: 472759:NHAL_RS12665
uniprot id: D5BWN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

472759:NHAL RS17065
gene id: 472759:NHAL_RS17065
uniprot id: D5C1J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

472759:NHAL RS10715
gene id: 472759:NHAL_RS10715
uniprot id: D5C570
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

472759:NHAL RS08515
gene id: 472759:NHAL_RS08515
uniprot id: D5C2A0
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

472759:NHAL RS09530
gene id: 472759:NHAL_RS09530
uniprot id: D5C3U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS02585
gene id: 472759:NHAL_RS02585
uniprot id: D5BW61
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS10785
gene id: 472759:NHAL_RS10785
uniprot id: D5C585
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

472759:NHAL RS02840
gene id: 472759:NHAL_RS02840
uniprot id: D5BWB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

472759:NHAL RS11710
gene id: 472759:NHAL_RS11710
uniprot id: D5BVR1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

472759:NHAL RS02165
gene id: 472759:NHAL_RS02165
uniprot id: D5BVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane

472759:NHAL RS10310
gene id: 472759:NHAL_RS10310
uniprot id: D5C4N3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

472759:NHAL RS14060
gene id: 472759:NHAL_RS14060
uniprot id: D5BYH7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

472759:NHAL RS17275
gene id: 472759:NHAL_RS17275
uniprot id: D5C1Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

472759:NHAL RS01605
gene id: 472759:NHAL_RS01605
uniprot id: D5BUX4
names: Subcellular Location Annotation
messages: Cytoplasm

472759:NHAL RS06700
gene id: 472759:NHAL_RS06700
uniprot id: D5C0W6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

472759:NHAL RS08445
gene id: 472759:NHAL_RS08445
uniprot id: D5C2X4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

472759:NHAL RS16765
gene id: 472759:NHAL_RS16765
uniprot id: D5C1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

472759:NHAL RS18105
gene id: 472759:NHAL_RS18105
uniprot id: D5C2S5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS08260
gene id: 472759:NHAL_RS08260
uniprot id: D5C2H1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

472759:NHAL RS03250
gene id: 472759:NHAL_RS03250
uniprot id: D5BWW2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

472759:NHAL RS01725
gene id: 472759:NHAL_RS01725
uniprot id: D5BVC0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

472759:NHAL RS01125
gene id: 472759:NHAL_RS01125
uniprot id: D5BUM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS06910
gene id: 472759:NHAL_RS06910
uniprot id: D5C111
names: Similarity
messages: Belongs to the peptidase A24 family.

472759:NHAL RS06105
gene id: 472759:NHAL_RS06105
uniprot id: D5C075
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

472759:NHAL RS05405
gene id: 472759:NHAL_RS05405
uniprot id: D5BZ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

472759:NHAL RS07030
gene id: 472759:NHAL_RS07030
uniprot id: D5C135
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

472759:NHAL RS17070
gene id: 472759:NHAL_RS17070
uniprot id: D5C1J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

472759:NHAL RS13180
gene id: 472759:NHAL_RS13180
uniprot id: D5BXB1
names: Similarity
messages: Belongs to the UPF0276 family.

472759:NHAL RS08145
gene id: 472759:NHAL_RS08145
uniprot id: D5C2E7
names: Function
names: Subcellular Location Annotation
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Periplasm

472759:NHAL RS14195
gene id: 472759:NHAL_RS14195
uniprot id: D5BYK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

472759:NHAL RS19855
gene id: 472759:NHAL_RS19855
uniprot id: D5C579
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

472759:NHAL RS18750
gene id: 472759:NHAL_RS18750
uniprot id: D5C3H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS09570
gene id: 472759:NHAL_RS09570
uniprot id: D5C3V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

472759:NHAL RS19225
gene id: 472759:NHAL_RS19225
uniprot id: D5C5B8
names: Similarity
messages: Belongs to the HsdR family.

472759:NHAL RS17410
gene id: 472759:NHAL_RS17410
uniprot id: D5C225
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

472759:NHAL RS17515
gene id: 472759:NHAL_RS17515
uniprot id: D5C246
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

472759:NHAL RS16810
gene id: 472759:NHAL_RS16810
uniprot id: D5C1D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

472759:NHAL RS00270
gene id: 472759:NHAL_RS00270
uniprot id: D5C486
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

472759:NHAL RS18160
gene id: 472759:NHAL_RS18160
uniprot id: D5C2T6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

472759:NHAL RS17020
gene id: 472759:NHAL_RS17020
uniprot id: D5C1I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

472759:NHAL RS13540
gene id: 472759:NHAL_RS13540
uniprot id: D5BXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

472759:NHAL RS11120
gene id: 472759:NHAL_RS11120
uniprot id: D5BV26
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

472759:NHAL RS07175
gene id: 472759:NHAL_RS07175
uniprot id: D5C163
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

472759:NHAL RS03330
gene id: 472759:NHAL_RS03330
uniprot id: D5BWY0
names: Similarity
messages: Belongs to the TrpC family.

472759:NHAL RS13710
gene id: 472759:NHAL_RS13710
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS01280
gene id: 472759:NHAL_RS01280
uniprot id: D5BUQ5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS12825
gene id: 472759:NHAL_RS12825
uniprot id: D5BX38
names: Similarity
messages: Belongs to the WrbA family.

472759:NHAL RS14435
gene id: 472759:NHAL_RS14435
uniprot id: D5BYP9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

472759:NHAL RS05730
gene id: 472759:NHAL_RS05730
uniprot id: D5BZM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

472759:NHAL RS07470
gene id: 472759:NHAL_RS07470
uniprot id: D5C1P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

472759:NHAL RS11960
gene id: 472759:NHAL_RS11960
uniprot id: D5BVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

472759:NHAL RS14190
gene id: 472759:NHAL_RS14190
uniprot id: D5BYK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

472759:NHAL RS14965
gene id: 472759:NHAL_RS14965
uniprot id: D5BZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

472759:NHAL RS18840
gene id: 472759:NHAL_RS18840
uniprot id: D5C3J0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

472759:NHAL RS03295
gene id: 472759:NHAL_RS03295
uniprot id: D5BWX3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

472759:NHAL RS17500
gene id: 472759:NHAL_RS17500
uniprot id: D5C243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

472759:NHAL RS10810
gene id: 472759:NHAL_RS10810
uniprot id: D5C591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

472759:NHAL RS03475
gene id: 472759:NHAL_RS03475
uniprot id: D5BX09
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

472759:NHAL RS11395
gene id: 472759:NHAL_RS11395
uniprot id: D5BV83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

472759:NHAL RS08565
gene id: 472759:NHAL_RS08565
uniprot id: D5C2Z7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

472759:NHAL RS00220
gene id: 472759:NHAL_RS00220
uniprot id: D5C476
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS14120
gene id: 472759:NHAL_RS14120
uniprot id: D5BYI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS11115
gene id: 472759:NHAL_RS11115
uniprot id: D5BV25
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

472759:NHAL RS05420
gene id: 472759:NHAL_RS05420
uniprot id: D5BZ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

472759:NHAL RS00870
gene id: 472759:NHAL_RS00870
uniprot id: D5C4W1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS12995
gene id: 472759:NHAL_RS12995
uniprot id: D5BX72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

472759:NHAL RS03590
gene id: 472759:NHAL_RS03590
uniprot id: D5BXF5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

472759:NHAL RS04280
gene id: 472759:NHAL_RS04280
uniprot id: D5BY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

472759:NHAL RS05600
gene id: 472759:NHAL_RS05600
uniprot id: D5BZK4
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

472759:NHAL RS12785
gene id: 472759:NHAL_RS12785
uniprot id: D5BX30
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

472759:NHAL RS17270
gene id: 472759:NHAL_RS17270
uniprot id: D5C1Z6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

472759:NHAL RS13065
gene id: 472759:NHAL_RS13065
uniprot id: D5BX86
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

472759:NHAL RS18700
gene id: 472759:NHAL_RS18700
uniprot id: D5C3G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

472759:NHAL RS16300
gene id: 472759:NHAL_RS16300
uniprot id: D5C0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

472759:NHAL RS02465
gene id: 472759:NHAL_RS02465
uniprot id: D5BW41
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS19035
gene id: 472759:NHAL_RS19035
uniprot id: D5C3Z7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

472759:NHAL RS11725
gene id: 472759:NHAL_RS11725
uniprot id: D5BVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

472759:NHAL RS16840
gene id: 472759:NHAL_RS16840
uniprot id: D5C1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

472759:NHAL RS18410
gene id: 472759:NHAL_RS18410
uniprot id: D5C3A4
names: Similarity
messages: Belongs to the UPF0235 family.

472759:NHAL RS09240
gene id: 472759:NHAL_RS09240
uniprot id: D5C3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

472759:NHAL RS18705
gene id: 472759:NHAL_RS18705
uniprot id: D5C3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS06255
gene id: 472759:NHAL_RS06255
uniprot id: D5C0A2
names: Similarity
messages: Belongs to the YoeB family.

472759:NHAL RS12820
gene id: 472759:NHAL_RS12820
uniprot id: D5BX37
names: Similarity
messages: Belongs to the ArsC family.

472759:NHAL RS13495
gene id: 472759:NHAL_RS13495
uniprot id: D5BXT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

472759:NHAL RS12790
gene id: 472759:NHAL_RS12790
uniprot id: D5BX31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

472759:NHAL RS15910
gene id: 472759:NHAL_RS15910
uniprot id: D5C0K0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

472759:NHAL RS15270
gene id: 472759:NHAL_RS15270
uniprot id: D5BZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

472759:NHAL RS07375
gene id: 472759:NHAL_RS07375
uniprot id: D5C1M6
names: Similarity
messages: Belongs to the MlaA family.

472759:NHAL RS06865
gene id: 472759:NHAL_RS06865
uniprot id: D5C102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

472759:NHAL RS15020
gene id: 472759:NHAL_RS15020
uniprot id: D5BZD4
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

472759:NHAL RS01195
gene id: 472759:NHAL_RS01195
uniprot id: D5BUP2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

472759:NHAL RS15255
gene id: 472759:NHAL_RS15255
uniprot id: D5BZI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

472759:NHAL RS02810
gene id: 472759:NHAL_RS02810
uniprot id: D5BWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

472759:NHAL RS01615
gene id: 472759:NHAL_RS01615
uniprot id: D5BUX6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

472759:NHAL RS10870
gene id: 472759:NHAL_RS10870
uniprot id: D5C5A3
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

472759:NHAL RS01950
gene id: 472759:NHAL_RS01950
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS08560
gene id: 472759:NHAL_RS08560
uniprot id: D5C2Z5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS02880
gene id: 472759:NHAL_RS02880
uniprot id: D5BWC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

472759:NHAL RS00510
gene id: 472759:NHAL_RS00510
uniprot id: D5C4P6
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

472759:NHAL RS17030
gene id: 472759:NHAL_RS17030
uniprot id: D5C1I3
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

472759:NHAL RS03920
gene id: 472759:NHAL_RS03920
uniprot id: D5BXL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

472759:NHAL RS19805
gene id: 472759:NHAL_RS19805
uniprot id: D5C3L5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

472759:NHAL RS03095
gene id: 472759:NHAL_RS03095
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS07055
gene id: 472759:NHAL_RS07055
uniprot id: D5C140
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

472759:NHAL RS17265
gene id: 472759:NHAL_RS17265
uniprot id: D5C1Z5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

472759:NHAL RS13005
gene id: 472759:NHAL_RS13005
uniprot id: D5BX74
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

472759:NHAL RS00375
gene id: 472759:NHAL_RS00375
uniprot id: D5C4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS13435
gene id: 472759:NHAL_RS13435
uniprot id: D5BXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

472759:NHAL RS15580
gene id: 472759:NHAL_RS15580
uniprot id: D5C012
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS10165
gene id: 472759:NHAL_RS10165
uniprot id: D5C4K3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

472759:NHAL RS02415
gene id: 472759:NHAL_RS02415
uniprot id: D5BW31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

472759:NHAL RS17885
gene id: 472759:NHAL_RS17885
uniprot id: D5C2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS10970
gene id: 472759:NHAL_RS10970
uniprot id: D5BUZ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS18765
gene id: 472759:NHAL_RS18765
uniprot id: D5C3H5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

472759:NHAL RS14605
gene id: 472759:NHAL_RS14605
uniprot id: D5BYT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

472759:NHAL RS12845
gene id: 472759:NHAL_RS12845
uniprot id: D5BX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS02355
gene id: 472759:NHAL_RS02355
uniprot id: D5BW19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

472759:NHAL RS00025
gene id: 472759:NHAL_RS00025
uniprot id: D5C439
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

472759:NHAL RS00385
gene id: 472759:NHAL_RS00385
uniprot id: D5C4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

472759:NHAL RS05655
gene id: 472759:NHAL_RS05655
uniprot id: D5BZL5
names: Similarity
messages: Belongs to the catalase family.

472759:NHAL RS19180
gene id: 472759:NHAL_RS19180
uniprot id: D5C427
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

472759:NHAL RS10720
gene id: 472759:NHAL_RS10720
uniprot id: D5C571
names: Similarity
messages: Belongs to the peptidase M16 family.

472759:NHAL RS06470
gene id: 472759:NHAL_RS06470
uniprot id: D5C0E9
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS02305
gene id: 472759:NHAL_RS02305
uniprot id: D5BVN1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

472759:NHAL RS17905
gene id: 472759:NHAL_RS17905
uniprot id: D5C2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS06075
gene id: 472759:NHAL_RS06075
uniprot id: D5C069
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

472759:NHAL RS13440
gene id: 472759:NHAL_RS13440
uniprot id: D5BXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

472759:NHAL RS18070
gene id: 472759:NHAL_RS18070
uniprot id: D5C2R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

472759:NHAL RS10400
gene id: 472759:NHAL_RS10400
uniprot id: D5C512
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS15590
gene id: 472759:NHAL_RS15590
uniprot id: D5C013
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

472759:NHAL RS12040
gene id: 472759:NHAL_RS12040
uniprot id: D5BVX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

472759:NHAL RS10385
gene id: 472759:NHAL_RS10385
uniprot id: D5C509
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS02525
gene id: 472759:NHAL_RS02525
uniprot id: D5BW49
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

472759:NHAL RS09220
gene id: 472759:NHAL_RS09220
uniprot id: D5C3P3
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

472759:NHAL RS11950
gene id: 472759:NHAL_RS11950
uniprot id: D5BVW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

472759:NHAL RS16780
gene id: 472759:NHAL_RS16780
uniprot id: D5C1D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

472759:NHAL RS12540
gene id: 472759:NHAL_RS12540
uniprot id: D5BWK4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

472759:NHAL RS03855
gene id: 472759:NHAL_RS03855
uniprot id: D5BXK7
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

472759:NHAL RS14445
gene id: 472759:NHAL_RS14445
uniprot id: D5BYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS00885
gene id: 472759:NHAL_RS00885
uniprot id: D5C4W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

472759:NHAL RS11360
gene id: 472759:NHAL_RS11360
uniprot id: D5BV76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

472759:NHAL RS11595
gene id: 472759:NHAL_RS11595
uniprot id: D5BVN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

472759:NHAL RS08875
gene id: 472759:NHAL_RS08875
uniprot id: D5C360
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS18420
gene id: 472759:NHAL_RS18420
uniprot id: D5C3A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

472759:NHAL RS00120
gene id: 472759:NHAL_RS00120
uniprot id: D5C458
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

472759:NHAL RS03335
gene id: 472759:NHAL_RS03335
uniprot id: D5BWY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS17050
gene id: 472759:NHAL_RS17050
uniprot id: D5C1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS15160
gene id: 472759:NHAL_RS15160
uniprot id: D5BZG0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

472759:NHAL RS12965
gene id: 472759:NHAL_RS12965
uniprot id: D5BX66
names: Subcellular Location Annotation
messages: Cytoplasm

472759:NHAL RS11585
gene id: 472759:NHAL_RS11585
uniprot id: D5BVN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

472759:NHAL RS03270
gene id: 472759:NHAL_RS03270
uniprot id: D5BWW7
names: Similarity
messages: Belongs to the UPF0229 family.

472759:NHAL RS04185
gene id: 472759:NHAL_RS04185
uniprot id: D5BXR8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

472759:NHAL RS08860
gene id: 472759:NHAL_RS08860
uniprot id: D5C357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS07930
gene id: 472759:NHAL_RS07930
uniprot id: D5C2A7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS11750
gene id: 472759:NHAL_RS11750
uniprot id: D5BVS0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

472759:NHAL RS04530
gene id: 472759:NHAL_RS04530
uniprot id: D5BYB3
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03725
gene id: 472759:NHAL_RS03725
uniprot id: D5BXI2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

472759:NHAL RS13695
gene id: 472759:NHAL_RS13695
uniprot id: D5BXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

472759:NHAL RS13810
gene id: 472759:NHAL_RS13810
uniprot id: D5BY03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

472759:NHAL RS11920
gene id: 472759:NHAL_RS11920
uniprot id: D5BVV4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

472759:NHAL RS06960
gene id: 472759:NHAL_RS06960
uniprot id: D5C121
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS19235
gene id: 472759:NHAL_RS19235
uniprot id: D5C5C0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS17015
gene id: 472759:NHAL_RS17015
uniprot id: D5C1H9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

472759:NHAL RS06750
gene id: 472759:NHAL_RS06750
uniprot id: D5C0X6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

472759:NHAL RS00330
gene id: 472759:NHAL_RS00330
uniprot id: D5C497
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS08450
gene id: 472759:NHAL_RS08450
uniprot id: D5C2X5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

472759:NHAL RS07215
gene id: 472759:NHAL_RS07215
uniprot id: D5C170
names: Similarity
messages: Belongs to the carbamate kinase family.

472759:NHAL RS18405
gene id: 472759:NHAL_RS18405
uniprot id: D5C3A3
names: Similarity
messages: Belongs to the YggT family.

472759:NHAL RS07245
gene id: 472759:NHAL_RS07245
uniprot id: D5C175
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

472759:NHAL RS17505
gene id: 472759:NHAL_RS17505
uniprot id: D5C244
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

472759:NHAL RS18920
gene id: 472759:NHAL_RS18920
uniprot id: D5C3K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS02560
gene id: 472759:NHAL_RS02560
uniprot id: D5BW56
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

472759:NHAL RS18640
gene id: 472759:NHAL_RS18640
uniprot id: D5C3E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS12690
gene id: 472759:NHAL_RS12690
uniprot id: D5BWN5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

472759:NHAL RS14035
gene id: 472759:NHAL_RS14035
uniprot id: D5BYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

472759:NHAL RS11400
gene id: 472759:NHAL_RS11400
uniprot id: D5BV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

472759:NHAL RS13720
gene id: 472759:NHAL_RS13720
uniprot id: D5BXY4
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

472759:NHAL RS00920
gene id: 472759:NHAL_RS00920
uniprot id: D5C4X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

472759:NHAL RS02475
gene id: 472759:NHAL_RS02475
uniprot id: D5BW43
names: Similarity
messages: Belongs to the peptidase S49 family.

472759:NHAL RS15335
gene id: 472759:NHAL_RS15335
uniprot id: D5BZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

472759:NHAL RS07005
gene id: 472759:NHAL_RS07005
uniprot id: D5C130
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

472759:NHAL RS15465
gene id: 472759:NHAL_RS15465
uniprot id: D5BZY9
names: Similarity
messages: Belongs to the peptidase S9C family.

472759:NHAL RS16945
gene id: 472759:NHAL_RS16945
uniprot id: D5C1G4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

472759:NHAL RS19135
gene id: 472759:NHAL_RS19135
uniprot id: D5C418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

472759:NHAL RS17460
gene id: 472759:NHAL_RS17460
uniprot id: D5C235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

472759:NHAL RS07100
gene id: 472759:NHAL_RS07100
uniprot id: D5C150
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

472759:NHAL RS02235
gene id: 472759:NHAL_RS02235
uniprot id: D5BVL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

472759:NHAL RS08320
gene id: 472759:NHAL_RS08320
uniprot id: D5C2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS03765
gene id: 472759:NHAL_RS03765
uniprot id: D5BXJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS16870
gene id: 472759:NHAL_RS16870
uniprot id: D5C1F0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

472759:NHAL RS11945
gene id: 472759:NHAL_RS11945
uniprot id: D5BVV9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

472759:NHAL RS11680
gene id: 472759:NHAL_RS11680
uniprot id: D5BVQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

472759:NHAL RS06980
gene id: 472759:NHAL_RS06980
uniprot id: D5C125
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

472759:NHAL RS04380
gene id: 472759:NHAL_RS04380
uniprot id: D5BY82
names: Similarity
messages: Belongs to the HepT RNase toxin family.

472759:NHAL RS15570
gene id: 472759:NHAL_RS15570
uniprot id: D5C010
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

472759:NHAL RS06125
gene id: 472759:NHAL_RS06125
uniprot id: D5C079
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

472759:NHAL RS09495
gene id: 472759:NHAL_RS09495
uniprot id: D5C3U1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

472759:NHAL RS08000
gene id: 472759:NHAL_RS08000
uniprot id: D5C2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

472759:NHAL RS03455
gene id: 472759:NHAL_RS03455
uniprot id: D5BX05
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

472759:NHAL RS11425
gene id: 472759:NHAL_RS11425
uniprot id: D5BV89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

472759:NHAL RS11970
gene id: 472759:NHAL_RS11970
uniprot id: D5BVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

472759:NHAL RS17295
gene id: 472759:NHAL_RS17295
uniprot id: D5C201
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

472759:NHAL RS06955
gene id: 472759:NHAL_RS06955
uniprot id: D5C120
names: Similarity
messages: Belongs to the GSP E family.

472759:NHAL RS13675
gene id: 472759:NHAL_RS13675
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS12105
gene id: 472759:NHAL_RS12105
uniprot id: D5BVY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

472759:NHAL RS16955
gene id: 472759:NHAL_RS16955
uniprot id: D5C1G6
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

472759:NHAL RS10195
gene id: 472759:NHAL_RS10195
uniprot id: D5C4K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

472759:NHAL RS00015
gene id: 472759:NHAL_RS00015
uniprot id: D5C437
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

472759:NHAL RS06080
gene id: 472759:NHAL_RS06080
uniprot id: D5C070
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS02865
gene id: 472759:NHAL_RS02865
uniprot id: D5BWB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

472759:NHAL RS04295
gene id: 472759:NHAL_RS04295
uniprot id: D5BY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

472759:NHAL RS05970
gene id: 472759:NHAL_RS05970
uniprot id: D5BZS8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

472759:NHAL RS07075
gene id: 472759:NHAL_RS07075
uniprot id: D5C145
names: Similarity
messages: Belongs to the UPF0047 family.

472759:NHAL RS18240
gene id: 472759:NHAL_RS18240
uniprot id: D5C2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

472759:NHAL RS16830
gene id: 472759:NHAL_RS16830
uniprot id: D5C1E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

472759:NHAL RS05410
gene id: 472759:NHAL_RS05410
uniprot id: D5BZ58
names: Similarity
messages: Belongs to the disproportionating enzyme family.

472759:NHAL RS17100
gene id: 472759:NHAL_RS17100
uniprot id: D5C1J8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

472759:NHAL RS06860
gene id: 472759:NHAL_RS06860
uniprot id: D5C101
names: Subcellular Location Annotation
messages: Cell inner membrane

472759:NHAL RS17465
gene id: 472759:NHAL_RS17465
uniprot id: D5C236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

472759:NHAL RS01035
gene id: 472759:NHAL_RS01035
uniprot id: D5C4Y8
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

472759:NHAL RS08805
gene id: 472759:NHAL_RS08805
uniprot id: D5C346
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

472759:NHAL RS01990
gene id: 472759:NHAL_RS01990
uniprot id: D5BVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

472759:NHAL RS13650
gene id: 472759:NHAL_RS13650
uniprot id: D5BXW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

472759:NHAL RS11365
gene id: 472759:NHAL_RS11365
uniprot id: D5BV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

472759:NHAL RS09245
gene id: 472759:NHAL_RS09245
uniprot id: D5C3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

472759:NHAL RS02890
gene id: 472759:NHAL_RS02890
uniprot id: D5BWC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

472759:NHAL RS02360
gene id: 472759:NHAL_RS02360
uniprot id: D5BW20
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

472759:NHAL RS12695
gene id: 472759:NHAL_RS12695
uniprot id: D5BWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

472759:NHAL RS18520
gene id: 472759:NHAL_RS18520
uniprot id: D5C3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

472759:NHAL RS02420
gene id: 472759:NHAL_RS02420
uniprot id: D5BW32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

472759:NHAL RS14030
gene id: 472759:NHAL_RS14030
uniprot id: D5BYH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

472759:NHAL RS18890
gene id: 472759:NHAL_RS18890
uniprot id: D5C3K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

472759:NHAL RS02145
gene id: 472759:NHAL_RS02145
uniprot id: D5BVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

472759:NHAL RS06600
gene id: 472759:NHAL_RS06600
uniprot id: D5C0H7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

472759:NHAL RS11625
gene id: 472759:NHAL_RS11625
uniprot id: D5BVP4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

472759:NHAL RS09095
gene id: 472759:NHAL_RS09095
uniprot id: D5C3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

472759:NHAL RS13545
gene id: 472759:NHAL_RS13545
uniprot id: D5BXU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS15230
gene id: 472759:NHAL_RS15230
uniprot id: D5BZH5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

472759:NHAL RS11605
gene id: 472759:NHAL_RS11605
uniprot id: D5BVP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

472759:NHAL RS13665
gene id: 472759:NHAL_RS13665
uniprot id: D5BXX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

472759:NHAL RS12075
gene id: 472759:NHAL_RS12075
uniprot id: D5BVY3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

472759:NHAL RS15320
gene id: 472759:NHAL_RS15320
uniprot id: D5BZW1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

472759:NHAL RS03535
gene id: 472759:NHAL_RS03535
uniprot id: D5BX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS12020
gene id: 472759:NHAL_RS12020
uniprot id: D5BVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

472759:NHAL RS00355
gene id: 472759:NHAL_RS00355
uniprot id: D5C4A2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

472759:NHAL RS09585
gene id: 472759:NHAL_RS09585
uniprot id: D5C3V9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS12380
gene id: 472759:NHAL_RS12380
uniprot id: D5BWH2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

472759:NHAL RS07680
gene id: 472759:NHAL_RS07680
uniprot id: D5C1T2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

472759:NHAL RS08685
gene id: 472759:NHAL_RS08685
uniprot id: D5C320
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

472759:NHAL RS04585
gene id: 472759:NHAL_RS04585
uniprot id: D5BYC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

472759:NHAL RS11235
gene id: 472759:NHAL_RS11235
uniprot id: D5BV50
names: Similarity
messages: Belongs to the BolA/IbaG family.

472759:NHAL RS15080
gene id: 472759:NHAL_RS15080
uniprot id: D5BZE5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

472759:NHAL RS02625
gene id: 472759:NHAL_RS02625
uniprot id: D5BW69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

472759:NHAL RS02650
gene id: 472759:NHAL_RS02650
uniprot id: D5BW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

472759:NHAL RS17350
gene id: 472759:NHAL_RS17350
uniprot id: D5C212
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS16930
gene id: 472759:NHAL_RS16930
uniprot id: D5C1G1
names: Similarity
messages: Belongs to the GcvT family.

472759:NHAL RS08795
gene id: 472759:NHAL_RS08795
uniprot id: D5C344
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS08885
gene id: 472759:NHAL_RS08885
uniprot id: D5C362
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

472759:NHAL RS05435
gene id: 472759:NHAL_RS05435
uniprot id: D5BZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS10175
gene id: 472759:NHAL_RS10175
uniprot id: D5C4K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

472759:NHAL RS05510
gene id: 472759:NHAL_RS05510
uniprot id: D5BZJ1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

472759:NHAL RS02055
gene id: 472759:NHAL_RS02055
uniprot id: D5BVI4
names: Similarity
messages: Belongs to the oxoprolinase family.

472759:NHAL RS03350
gene id: 472759:NHAL_RS03350
uniprot id: D5BWY4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

472759:NHAL RS01710
gene id: 472759:NHAL_RS01710
uniprot id: D5BVB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

472759:NHAL RS04200
gene id: 472759:NHAL_RS04200
uniprot id: D5BXS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

472759:NHAL RS13335
gene id: 472759:NHAL_RS13335
uniprot id: D5BXD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

472759:NHAL RS14320
gene id: 472759:NHAL_RS14320
uniprot id: D5BYM6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

472759:NHAL RS15140
gene id: 472759:NHAL_RS15140
uniprot id: D5BZF6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

472759:NHAL RS12860
gene id: 472759:NHAL_RS12860
uniprot id: D5BX44
names: Similarity
messages: Belongs to the Nudix hydrolase family.

472759:NHAL RS17095
gene id: 472759:NHAL_RS17095
uniprot id: D5C1J7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

472759:NHAL RS08715
gene id: 472759:NHAL_RS08715
uniprot id: D5C327
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS17655
gene id: 472759:NHAL_RS17655
uniprot id: D5C276
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS16655
gene id: 472759:NHAL_RS16655
uniprot id: D5C1A8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

472759:NHAL RS17900
gene id: 472759:NHAL_RS17900
uniprot id: D5C2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS16505
gene id: 472759:NHAL_RS16505
uniprot id: D5C0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

472759:NHAL RS12300
gene id: 472759:NHAL_RS12300
uniprot id: D5BWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

472759:NHAL RS04355
gene id: 472759:NHAL_RS04355
uniprot id: D5BY78
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

472759:NHAL RS16315
gene id: 472759:NHAL_RS16315
uniprot id: D5C0S3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

472759:NHAL RS08460
gene id: 472759:NHAL_RS08460
uniprot id: D5C2X7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS08960
gene id: 472759:NHAL_RS08960
uniprot id: D5C359
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS11305
gene id: 472759:NHAL_RS11305
uniprot id: D5BV65
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

472759:NHAL RS06805
gene id: 472759:NHAL_RS06805
uniprot id: D5C0Z0
names: Similarity
messages: Belongs to the AdoMet synthase family.

472759:NHAL RS03400
gene id: 472759:NHAL_RS03400
uniprot id: D5BWZ4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

472759:NHAL RS00105
gene id: 472759:NHAL_RS00105
uniprot id: D5C455
names: Similarity
messages: Belongs to the peptidase S41A family.

472759:NHAL RS14130
gene id: 472759:NHAL_RS14130
uniprot id: D5BYJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

472759:NHAL RS03115
gene id: 472759:NHAL_RS03115
uniprot id: D5BWT5
names: Similarity
messages: Belongs to the RelE toxin family.

472759:NHAL RS11125
gene id: 472759:NHAL_RS11125
uniprot id: D5BV27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

472759:NHAL RS12740
gene id: 472759:NHAL_RS12740
uniprot id: D5BWP7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

472759:NHAL RS01095
gene id: 472759:NHAL_RS01095
uniprot id: D5BUM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

472759:NHAL RS13565
gene id: 472759:NHAL_RS13565
uniprot id: D5BXV3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

472759:NHAL RS04425
gene id: 472759:NHAL_RS04425
uniprot id: D5BY91
names: Similarity
messages: Belongs to the SfsA family.

472759:NHAL RS07460
gene id: 472759:NHAL_RS07460
uniprot id: D5C1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

472759:NHAL RS09535
gene id: 472759:NHAL_RS09535
uniprot id: D5C3U9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS08745
gene id: 472759:NHAL_RS08745
uniprot id: D5C334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS04510
gene id: 472759:NHAL_RS04510
uniprot id: D5BYA9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

472759:NHAL RS06110
gene id: 472759:NHAL_RS06110
uniprot id: D5C076
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

472759:NHAL RS17035
gene id: 472759:NHAL_RS17035
uniprot id: D5C1I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

472759:NHAL RS09635
gene id: 472759:NHAL_RS09635
uniprot id: D5C3X0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS03585
gene id: 472759:NHAL_RS03585
uniprot id: D5BXF4
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11820
gene id: 472759:NHAL_RS11820
uniprot id: D5BVT4
names: Similarity
messages: Belongs to the UPF0166 family.

472759:NHAL RS12190
gene id: 472759:NHAL_RS12190
uniprot id: D5BW08
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS02660
gene id: 472759:NHAL_RS02660
uniprot id: D5BW76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

472759:NHAL RS18735
gene id: 472759:NHAL_RS18735
uniprot id: D5C3G8
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

472759:NHAL RS08760
gene id: 472759:NHAL_RS08760
uniprot id: D5C337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

472759:NHAL RS15770
gene id: 472759:NHAL_RS15770
uniprot id: D5C046
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03620
gene id: 472759:NHAL_RS03620
uniprot id: D5BXG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

472759:NHAL RS18725
gene id: 472759:NHAL_RS18725
uniprot id: D5C3G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

472759:NHAL RS17875
gene id: 472759:NHAL_RS17875
uniprot id: D5C2N0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

472759:NHAL RS15390
gene id: 472759:NHAL_RS15390
uniprot id: D5BZX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

472759:NHAL RS19155
gene id: 472759:NHAL_RS19155
uniprot id: D5C422
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

472759:NHAL RS04195
gene id: 472759:NHAL_RS04195
uniprot id: D5BXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS13950
gene id: 472759:NHAL_RS13950
uniprot id: D5BY31
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS17415
gene id: 472759:NHAL_RS17415
uniprot id: D5C226
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

472759:NHAL RS10380
gene id: 472759:NHAL_RS10380
uniprot id: D5C508
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS17525
gene id: 472759:NHAL_RS17525
uniprot id: D5C248
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

472759:NHAL RS15550
gene id: 472759:NHAL_RS15550
uniprot id: D5C006
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

472759:NHAL RS06350
gene id: 472759:NHAL_RS06350
uniprot id: D5C0C3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

472759:NHAL RS00095
gene id: 472759:NHAL_RS00095
uniprot id: D5C453
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

472759:NHAL RS06610
gene id: 472759:NHAL_RS06610
uniprot id: D5C0H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS18875
gene id: 472759:NHAL_RS18875
uniprot id: D5C3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

472759:NHAL RS05425
gene id: 472759:NHAL_RS05425
uniprot id: D5BZ61
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

472759:NHAL RS18550
gene id: 472759:NHAL_RS18550
uniprot id: D5C3D2
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS00265
gene id: 472759:NHAL_RS00265
uniprot id: D5C485
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS17340
gene id: 472759:NHAL_RS17340
uniprot id: D5C210
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS16640
gene id: 472759:NHAL_RS16640
uniprot id: D5C1A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS08550
gene id: 472759:NHAL_RS08550
uniprot id: D5C2Z3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

472759:NHAL RS01140
gene id: 472759:NHAL_RS01140
uniprot id: D5BUN1
names: Similarity
messages: Belongs to the PspA/IM30 family.

472759:NHAL RS18455
gene id: 472759:NHAL_RS18455
uniprot id: D5C3B3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

472759:NHAL RS12480
gene id: 472759:NHAL_RS12480
uniprot id: D5BWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS08980
gene id: 472759:NHAL_RS08980
uniprot id: D5C363
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16430
gene id: 472759:NHAL_RS16430
uniprot id: D5C0U3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

472759:NHAL RS06005
gene id: 472759:NHAL_RS06005
uniprot id: D5BZT5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

472759:NHAL RS17910
gene id: 472759:NHAL_RS17910
uniprot id: D5C2N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS08985
gene id: 472759:NHAL_RS08985
uniprot id: D5C364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS12750
gene id: 472759:NHAL_RS12750
uniprot id: D5BWP9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

472759:NHAL RS06635
gene id: 472759:NHAL_RS06635
uniprot id: D5C0I4
names: Similarity
messages: Belongs to the HypD family.

472759:NHAL RS13330
gene id: 472759:NHAL_RS13330
uniprot id: D5BXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

472759:NHAL RS09430
gene id: 472759:NHAL_RS09430
uniprot id: D5C3S8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

472759:NHAL RS10905
gene id: 472759:NHAL_RS10905
uniprot id: D5C5B0
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

472759:NHAL RS11350
gene id: 472759:NHAL_RS11350
uniprot id: D5BV74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

472759:NHAL RS06120
gene id: 472759:NHAL_RS06120
uniprot id: D5C078
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

472759:NHAL RS10725
gene id: 472759:NHAL_RS10725
uniprot id: D5C572
names: Similarity
messages: Belongs to the peptidase M16 family.

472759:NHAL RS04560
gene id: 472759:NHAL_RS04560
uniprot id: D5BYB9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

472759:NHAL RS11620
gene id: 472759:NHAL_RS11620
uniprot id: D5BVP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

472759:NHAL RS08675
gene id: 472759:NHAL_RS08675
uniprot id: D5C318
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

472759:NHAL RS17105
gene id: 472759:NHAL_RS17105
uniprot id: D5C1J9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

472759:NHAL RS08800
gene id: 472759:NHAL_RS08800
uniprot id: D5C345
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS17890
gene id: 472759:NHAL_RS17890
uniprot id: D5C2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

472759:NHAL RS03200
gene id: 472759:NHAL_RS03200
uniprot id: D5BWV2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

472759:NHAL RS16750
gene id: 472759:NHAL_RS16750
uniprot id: D5C1C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

472759:NHAL RS16500
gene id: 472759:NHAL_RS16500
uniprot id: D5C0V9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

472759:NHAL RS03490
gene id: 472759:NHAL_RS03490
uniprot id: D5BX12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

472759:NHAL RS00820
gene id: 472759:NHAL_RS00820
uniprot id: D5C4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

472759:NHAL RS19160
gene id: 472759:NHAL_RS19160
uniprot id: D5C423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

472759:NHAL RS07060
gene id: 472759:NHAL_RS07060
uniprot id: D5C141
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

472759:NHAL RS13775
gene id: 472759:NHAL_RS13775
uniprot id: D5BXZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

472759:NHAL RS08455
gene id: 472759:NHAL_RS08455
uniprot id: D5C2X6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

472759:NHAL RS05365
gene id: 472759:NHAL_RS05365
uniprot id: D5BZ49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS18450
gene id: 472759:NHAL_RS18450
uniprot id: D5C3B2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS08050
gene id: 472759:NHAL_RS08050
uniprot id: D5C2C8
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS01995
gene id: 472759:NHAL_RS01995
uniprot id: D5BVH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

472759:NHAL RS01800
gene id: 472759:NHAL_RS01800
uniprot id: D5BVD5
names: Similarity
messages: Belongs to the group II decarboxylase family.

472759:NHAL RS06615
gene id: 472759:NHAL_RS06615
uniprot id: D5C0I0
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

472759:NHAL RS07660
gene id: 472759:NHAL_RS07660
uniprot id: D5C1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS11825
gene id: 472759:NHAL_RS11825
uniprot id: D5BVT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

472759:NHAL RS04320
gene id: 472759:NHAL_RS04320
uniprot id: D5BY71
names: Similarity
messages: Belongs to the RecJ family.

472759:NHAL RS12780
gene id: 472759:NHAL_RS12780
uniprot id: D5BX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

472759:NHAL RS12745
gene id: 472759:NHAL_RS12745
uniprot id: D5BWP8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS10450
gene id: 472759:NHAL_RS10450
uniprot id: D5C522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS07825
gene id: 472759:NHAL_RS07825
uniprot id: D5C1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS06620
gene id: 472759:NHAL_RS06620
uniprot id: D5C0I1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

472759:NHAL RS01665
gene id: 472759:NHAL_RS01665
uniprot id: D5BUY6
names: Similarity
messages: Belongs to the MlaA family.

472759:NHAL RS02410
gene id: 472759:NHAL_RS02410
uniprot id: D5BW30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

472759:NHAL RS09425
gene id: 472759:NHAL_RS09425
uniprot id: D5C3S7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

472759:NHAL RS15090
gene id: 472759:NHAL_RS15090
uniprot id: D5BZE6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

472759:NHAL RS11300
gene id: 472759:NHAL_RS11300
uniprot id: D5BV64
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

472759:NHAL RS08690
gene id: 472759:NHAL_RS08690
uniprot id: D5C321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS09775
gene id: 472759:NHAL_RS09775
uniprot id: D5C4D4
names: Similarity
messages: Belongs to the UPF0260 family.

472759:NHAL RS07675
gene id: 472759:NHAL_RS07675
uniprot id: D5C1T1
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

472759:NHAL RS04440
gene id: 472759:NHAL_RS04440
uniprot id: D5BY94
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

472759:NHAL RS10305
gene id: 472759:NHAL_RS10305
uniprot id: D5C4N2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

472759:NHAL RS12140
gene id: 472759:NHAL_RS12140
uniprot id: D5BVZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

472759:NHAL RS03895
gene id: 472759:NHAL_RS03895
uniprot id: D5BXL6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

472759:NHAL RS13075
gene id: 472759:NHAL_RS13075
uniprot id: D5BX88
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

472759:NHAL RS10475
gene id: 472759:NHAL_RS10475
uniprot id: D5C528
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

472759:NHAL RS08125
gene id: 472759:NHAL_RS08125
uniprot id: D5C2E3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

472759:NHAL RS15265
gene id: 472759:NHAL_RS15265
uniprot id: D5BZU9
names: Similarity
messages: Belongs to the FrmR/RcnR family.

472759:NHAL RS08975
gene id: 472759:NHAL_RS08975
uniprot id: D5C362
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

472759:NHAL RS03345
gene id: 472759:NHAL_RS03345
uniprot id: D5BWY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

472759:NHAL RS11715
gene id: 472759:NHAL_RS11715
uniprot id: D5BVR2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

472759:NHAL RS11310
gene id: 472759:NHAL_RS11310
uniprot id: D5BV66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

472759:NHAL RS11880
gene id: 472759:NHAL_RS11880
uniprot id: D5BVU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS03365
gene id: 472759:NHAL_RS03365
uniprot id: D5BWY7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

472759:NHAL RS10160
gene id: 472759:NHAL_RS10160
uniprot id: D5C4K2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

472759:NHAL RS14730
gene id: 472759:NHAL_RS14730
uniprot id: D5BZ78
names: Similarity
messages: Belongs to the PrpD family.

472759:NHAL RS06830
gene id: 472759:NHAL_RS06830
uniprot id: D5C0Z5
names: Similarity
messages: Belongs to the TPP enzyme family.

472759:NHAL RS00280
gene id: 472759:NHAL_RS00280
uniprot id: D5C488
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

472759:NHAL RS18040
gene id: 472759:NHAL_RS18040
uniprot id: D5C2R2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

472759:NHAL RS04420
gene id: 472759:NHAL_RS04420
uniprot id: D5BY89
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS19140
gene id: 472759:NHAL_RS19140
uniprot id: D5C419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

472759:NHAL RS07960
gene id: 472759:NHAL_RS07960
uniprot id: D5C2B2
names: Similarity
messages: Belongs to the peptidase S16 family.

472759:NHAL RS19055
gene id: 472759:NHAL_RS19055
uniprot id: D5C401
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

472759:NHAL RS08890
gene id: 472759:NHAL_RS08890
uniprot id: D5C363
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16950
gene id: 472759:NHAL_RS16950
uniprot id: D5C1G5
names: Subunit
messages: Homotetramer.

472759:NHAL RS10770
gene id: 472759:NHAL_RS10770
uniprot id: D5C582
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

472759:NHAL RS10485
gene id: 472759:NHAL_RS10485
uniprot id: D5C530
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

472759:NHAL RS18720
gene id: 472759:NHAL_RS18720
uniprot id: D5C3G5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

472759:NHAL RS09370
gene id: 472759:NHAL_RS09370
uniprot id: D5C3R7
names: Similarity
messages: Belongs to the HesB/IscA family.

472759:NHAL RS02060
gene id: 472759:NHAL_RS02060
uniprot id: D5BVI5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS03670
gene id: 472759:NHAL_RS03670
uniprot id: D5BXH1
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

472759:NHAL RS01745
gene id: 472759:NHAL_RS01745
uniprot id: D5BVC4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS03255
gene id: 472759:NHAL_RS03255
uniprot id: D5BWW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS17440
gene id: 472759:NHAL_RS17440
uniprot id: D5C231
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

472759:NHAL RS16675
gene id: 472759:NHAL_RS16675
uniprot id: D5C1B3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

472759:NHAL RS09740
gene id: 472759:NHAL_RS09740
uniprot id: D5C4C7
names: Similarity
messages: Belongs to the peptidase U62 family.

472759:NHAL RS02720
gene id: 472759:NHAL_RS02720
uniprot id: D5BW88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

472759:NHAL RS17545
gene id: 472759:NHAL_RS17545
uniprot id: D5C252
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

472759:NHAL RS12575
gene id: 472759:NHAL_RS12575
uniprot id: D5BWL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

472759:NHAL RS14290
gene id: 472759:NHAL_RS14290
uniprot id: D5BYM0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

472759:NHAL RS01355
gene id: 472759:NHAL_RS01355
uniprot id: D5BUS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

472759:NHAL RS15900
gene id: 472759:NHAL_RS15900
uniprot id: D5C0J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS13110
gene id: 472759:NHAL_RS13110
uniprot id: D5BX96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

472759:NHAL RS11990
gene id: 472759:NHAL_RS11990
uniprot id: D5BVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

472759:NHAL RS13010
gene id: 472759:NHAL_RS13010
uniprot id: D5BX75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS05100
gene id: 472759:NHAL_RS05100
uniprot id: D5BYZ9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS04865
gene id: 472759:NHAL_RS04865
uniprot id: D5BYV0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS01740
gene id: 472759:NHAL_RS01740
uniprot id: D5BVC3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

472759:NHAL RS13515
gene id: 472759:NHAL_RS13515
uniprot id: D5BXU3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

472759:NHAL RS09230
gene id: 472759:NHAL_RS09230
uniprot id: D5C3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

472759:NHAL RS11035
gene id: 472759:NHAL_RS11035
uniprot id: D5BV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

472759:NHAL RS15130
gene id: 472759:NHAL_RS15130
uniprot id: D5BZF4
names: Similarity
messages: Belongs to the fabD family.

472759:NHAL RS14540
gene id: 472759:NHAL_RS14540
uniprot id: D5BYS2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

472759:NHAL RS09455
gene id: 472759:NHAL_RS09455
uniprot id: D5C3T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

472759:NHAL RS11490
gene id: 472759:NHAL_RS11490
uniprot id: D5BVA0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

472759:NHAL RS05400
gene id: 472759:NHAL_RS05400
uniprot id: D5BZ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

472759:NHAL RS06000
gene id: 472759:NHAL_RS06000
uniprot id: D5BZT4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

472759:NHAL RS01540
gene id: 472759:NHAL_RS01540
uniprot id: D5BUW0
names: Similarity
messages: Belongs to the CFA/CMAS family.

472759:NHAL RS11290
gene id: 472759:NHAL_RS11290
uniprot id: D5BV62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

472759:NHAL RS06115
gene id: 472759:NHAL_RS06115
uniprot id: D5C077
names: Similarity
messages: Belongs to the CopC family.

472759:NHAL RS03715
gene id: 472759:NHAL_RS03715
uniprot id: D5BXI0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

472759:NHAL RS10780
gene id: 472759:NHAL_RS10780
uniprot id: D5C584
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

472759:NHAL RS06925
gene id: 472759:NHAL_RS06925
uniprot id: D5C114
names: Similarity
messages: Belongs to the bacterial secretin family.

472759:NHAL RS02385
gene id: 472759:NHAL_RS02385
uniprot id: D5BW25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

472759:NHAL RS18275
gene id: 472759:NHAL_RS18275
uniprot id: D5C2V8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS11735
gene id: 472759:NHAL_RS11735
uniprot id: D5BVR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

472759:NHAL RS05685
gene id: 472759:NHAL_RS05685
uniprot id: D5BZM0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS01655
gene id: 472759:NHAL_RS01655
uniprot id: D5BUY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

472759:NHAL RS02845
gene id: 472759:NHAL_RS02845
uniprot id: D5BWB4
names: Similarity
messages: Belongs to the citrate synthase family.

472759:NHAL RS11245
gene id: 472759:NHAL_RS11245
uniprot id: D5BV52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

472759:NHAL RS08020
gene id: 472759:NHAL_RS08020
uniprot id: D5C2C3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

472759:NHAL RS17520
gene id: 472759:NHAL_RS17520
uniprot id: D5C247
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

472759:NHAL RS01080
gene id: 472759:NHAL_RS01080
uniprot id: D5BUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

472759:NHAL RS17970
gene id: 472759:NHAL_RS17970
uniprot id: D5C2P8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

472759:NHAL RS09510
gene id: 472759:NHAL_RS09510
uniprot id: D5C3U4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

472759:NHAL RS02735
gene id: 472759:NHAL_RS02735
uniprot id: D5BW91
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS13835
gene id: 472759:NHAL_RS13835
uniprot id: D5BY08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

472759:NHAL RS15155
gene id: 472759:NHAL_RS15155
uniprot id: D5BZF9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

472759:NHAL RS11610
gene id: 472759:NHAL_RS11610
uniprot id: D5BVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

472759:NHAL RS18090
gene id: 472759:NHAL_RS18090
uniprot id: D5C2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

472759:NHAL RS02915
gene id: 472759:NHAL_RS02915
uniprot id: D5BWC8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

472759:NHAL RS05920
gene id: 472759:NHAL_RS05920
uniprot id: D5BZR8
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS00760
gene id: 472759:NHAL_RS00760
uniprot id: D5C4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS05240
gene id: 472759:NHAL_RS05240
uniprot id: D5BZ25
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

472759:NHAL RS00365
gene id: 472759:NHAL_RS00365
uniprot id: D5C4A4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

472759:NHAL RS02795
gene id: 472759:NHAL_RS02795
uniprot id: D5BWA3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

472759:NHAL RS05280
gene id: 472759:NHAL_RS05280
uniprot id: D5BZ32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

472759:NHAL RS16570
gene id: 472759:NHAL_RS16570
uniprot id: D5C191
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

472759:NHAL RS17935
gene id: 472759:NHAL_RS17935
uniprot id: D5C2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS02155
gene id: 472759:NHAL_RS02155
uniprot id: D5BVK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS11940
gene id: 472759:NHAL_RS11940
uniprot id: D5BVV8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

472759:NHAL RS18125
gene id: 472759:NHAL_RS18125
uniprot id: D5C2S8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

472759:NHAL RS16295
gene id: 472759:NHAL_RS16295
uniprot id: D5C0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

472759:NHAL RS02745
gene id: 472759:NHAL_RS02745
uniprot id: D5BW93
names: Similarity
messages: Belongs to the Nudix hydrolase family.

472759:NHAL RS08150
gene id: 472759:NHAL_RS08150
uniprot id: D5C2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS03655
gene id: 472759:NHAL_RS03655
uniprot id: D5BXG8
names: Similarity
messages: Belongs to the XFP family.

472759:NHAL RS13790
gene id: 472759:NHAL_RS13790
uniprot id: D5BXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

472759:NHAL RS16990
gene id: 472759:NHAL_RS16990
uniprot id: D5C1H4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

472759:NHAL RS12245
gene id: 472759:NHAL_RS12245
uniprot id: D5BWE4
names: Function
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

472759:NHAL RS18885
gene id: 472759:NHAL_RS18885
uniprot id: D5C3J9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

472759:NHAL RS01085
gene id: 472759:NHAL_RS01085
uniprot id: D5BUM1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16645
gene id: 472759:NHAL_RS16645
uniprot id: D5C1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

472759:NHAL RS01045
gene id: 472759:NHAL_RS01045
uniprot id: D5C4Z0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

472759:NHAL RS18235
gene id: 472759:NHAL_RS18235
uniprot id: D5C2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

472759:NHAL RS05715
gene id: 472759:NHAL_RS05715
uniprot id: D5BZM6
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03680
gene id: 472759:NHAL_RS03680
uniprot id: D5BXH3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS01075
gene id: 472759:NHAL_RS01075
uniprot id: D5BUL9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

472759:NHAL RS14375
gene id: 472759:NHAL_RS14375
uniprot id: D5BYN7
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS05215
gene id: 472759:NHAL_RS05215
uniprot id: D5BZ20
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS15940
gene id: 472759:NHAL_RS15940
uniprot id: D5C0K6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

472759:NHAL RS02550
gene id: 472759:NHAL_RS02550
uniprot id: D5BW54
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

472759:NHAL RS18600
gene id: 472759:NHAL_RS18600
uniprot id: D5C3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

472759:NHAL RS19630
gene id: 472759:NHAL_RS19630
uniprot id: D5BY76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

472759:NHAL RS11390
gene id: 472759:NHAL_RS11390
uniprot id: D5BV82
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

472759:NHAL RS03380
gene id: 472759:NHAL_RS03380
uniprot id: D5BWZ0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

472759:NHAL RS03520
gene id: 472759:NHAL_RS03520
uniprot id: D5BX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

472759:NHAL RS09285
gene id: 472759:NHAL_RS09285
uniprot id: D5C3Q3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

472759:NHAL RS19380
gene id: 472759:NHAL_RS19380
uniprot id: D5C5F1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS00370
gene id: 472759:NHAL_RS00370
uniprot id: D5C4A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS15915
gene id: 472759:NHAL_RS15915
uniprot id: D5C0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

472759:NHAL RS02040
gene id: 472759:NHAL_RS02040
uniprot id: D5BVI1
names: Similarity
messages: Belongs to the SCO1/2 family.

472759:NHAL RS07050
gene id: 472759:NHAL_RS07050
uniprot id: D5C139
names: Similarity
messages: Belongs to the heat shock protein 70 family.

472759:NHAL RS12660
gene id: 472759:NHAL_RS12660
uniprot id: D5BWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

472759:NHAL RS18020
gene id: 472759:NHAL_RS18020
uniprot id: D5C2Q8
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

472759:NHAL RS05890
gene id: 472759:NHAL_RS05890
uniprot id: D5BZR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

472759:NHAL RS06520
gene id: 472759:NHAL_RS06520
uniprot id: D5C0F9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

472759:NHAL RS13310
gene id: 472759:NHAL_RS13310
uniprot id: D5BXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

472759:NHAL RS03530
gene id: 472759:NHAL_RS03530
uniprot id: D5BX20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

472759:NHAL RS13000
gene id: 472759:NHAL_RS13000
uniprot id: D5BX73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

472759:NHAL RS08500
gene id: 472759:NHAL_RS08500
uniprot id: D5C2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS18080
gene id: 472759:NHAL_RS18080
uniprot id: D5C2S0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

472759:NHAL RS05800
gene id: 472759:NHAL_RS05800
uniprot id: D5BZP3
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11765
gene id: 472759:NHAL_RS11765
uniprot id: D5BVS3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS10035
gene id: 472759:NHAL_RS10035
uniprot id: D5C4I1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

472759:NHAL RS14790
gene id: 472759:NHAL_RS14790
uniprot id: D5BZ91
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

472759:NHAL RS10260
gene id: 472759:NHAL_RS10260
uniprot id: D5C4M3
names: Similarity
messages: Belongs to the LOG family.

472759:NHAL RS01910
gene id: 472759:NHAL_RS01910
uniprot id: D5BVF5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

472759:NHAL RS12155
gene id: 472759:NHAL_RS12155
uniprot id: D5BVZ9
names: Similarity
messages: Belongs to the peptidase C56 family.

472759:NHAL RS04390
gene id: 472759:NHAL_RS04390
uniprot id: D5BY84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

472759:NHAL RS14090
gene id: 472759:NHAL_RS14090
uniprot id: D5BYI2
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS12990
gene id: 472759:NHAL_RS12990
uniprot id: D5BX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

472759:NHAL RS07065
gene id: 472759:NHAL_RS07065
uniprot id: D5C142
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

472759:NHAL RS19205
gene id: 472759:NHAL_RS19205
uniprot id: D5C432
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

472759:NHAL RS12770
gene id: 472759:NHAL_RS12770
uniprot id: D5BX27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS18255
gene id: 472759:NHAL_RS18255
uniprot id: D5C2V4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

472759:NHAL RS01640
gene id: 472759:NHAL_RS01640
uniprot id: D5BUY1
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

472759:NHAL RS07730
gene id: 472759:NHAL_RS07730
uniprot id: D5C1U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

472759:NHAL RS00145
gene id: 472759:NHAL_RS00145
uniprot id: D5C463
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

472759:NHAL RS02750
gene id: 472759:NHAL_RS02750
uniprot id: D5BW94
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS00040
gene id: 472759:NHAL_RS00040
uniprot id: D5C442
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

472759:NHAL RS09575
gene id: 472759:NHAL_RS09575
uniprot id: D5C3V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

472759:NHAL RS06640
gene id: 472759:NHAL_RS06640
uniprot id: D5C0I5
names: Similarity
messages: Belongs to the HypE family.

472759:NHAL RS19020
gene id: 472759:NHAL_RS19020
uniprot id: D5C3Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

472759:NHAL RS10790
gene id: 472759:NHAL_RS10790
uniprot id: D5C586
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

472759:NHAL RS12805
gene id: 472759:NHAL_RS12805
uniprot id: D5BX34
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

472759:NHAL RS11730
gene id: 472759:NHAL_RS11730
uniprot id: D5BVR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

472759:NHAL RS13895
gene id: 472759:NHAL_RS13895
uniprot id: D5BY20
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS10315
gene id: 472759:NHAL_RS10315
uniprot id: D5C4N4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS02805
gene id: 472759:NHAL_RS02805
uniprot id: D5BWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

472759:NHAL RS18100
gene id: 472759:NHAL_RS18100
uniprot id: D5C2S4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS05915
gene id: 472759:NHAL_RS05915
uniprot id: D5BZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

472759:NHAL RS00860
gene id: 472759:NHAL_RS00860
uniprot id: D5C4V9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

472759:NHAL RS03635
gene id: 472759:NHAL_RS03635
uniprot id: D5BXG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS06375
gene id: 472759:NHAL_RS06375
uniprot id: D5C0C8
names: Similarity
messages: Belongs to the peptidase M1 family.

472759:NHAL RS13425
gene id: 472759:NHAL_RS13425
uniprot id: D5BXS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

472759:NHAL RS11190
gene id: 472759:NHAL_RS11190
uniprot id: D5BV40
names: Similarity
messages: Belongs to the DprA/Smf family.

472759:NHAL RS05190
gene id: 472759:NHAL_RS05190
uniprot id: D5BZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

472759:NHAL RS10350
gene id: 472759:NHAL_RS10350
uniprot id: D5C502
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

472759:NHAL RS05325
gene id: 472759:NHAL_RS05325
uniprot id: D5BZ41
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

472759:NHAL RS12420
gene id: 472759:NHAL_RS12420
uniprot id: D5BWH9
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS12250
gene id: 472759:NHAL_RS12250
uniprot id: D5BWE5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

472759:NHAL RS15425
gene id: 472759:NHAL_RS15425
uniprot id: D5BZY2
names: Similarity
messages: Belongs to the glutamate synthase family.

472759:NHAL RS18925
gene id: 472759:NHAL_RS18925
uniprot id: D5C3K7
names: Similarity
messages: Belongs to the UPF0758 family.

472759:NHAL RS04255
gene id: 472759:NHAL_RS04255
uniprot id: D5BY57
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS18530
gene id: 472759:NHAL_RS18530
uniprot id: D5C3C8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

472759:NHAL RS14805
gene id: 472759:NHAL_RS14805
uniprot id: D5BZ94
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

472759:NHAL RS10425
gene id: 472759:NHAL_RS10425
uniprot id: D5C517
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS02580
gene id: 472759:NHAL_RS02580
uniprot id: D5BW60
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

472759:NHAL RS04600
gene id: 472759:NHAL_RS04600
uniprot id: D5BYC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS13405
gene id: 472759:NHAL_RS13405
uniprot id: D5BXS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

472759:NHAL RS03710
gene id: 472759:NHAL_RS03710
uniprot id: D5BXH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

472759:NHAL RS00125
gene id: 472759:NHAL_RS00125
uniprot id: D5C459
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

472759:NHAL RS09080
gene id: 472759:NHAL_RS09080
uniprot id: D5C3L8
names: Similarity
messages: Belongs to the peptidase M16 family.

472759:NHAL RS09820
gene id: 472759:NHAL_RS09820
uniprot id: D5C4E3
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS05430
gene id: 472759:NHAL_RS05430
uniprot id: D5BZ62
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS14235
gene id: 472759:NHAL_RS14235
uniprot id: D5BYL1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03745
gene id: 472759:NHAL_RS03745
uniprot id: D5BXI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

472759:NHAL RS11720
gene id: 472759:NHAL_RS11720
uniprot id: D5BVR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

472759:NHAL RS11295
gene id: 472759:NHAL_RS11295
uniprot id: D5BV63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

472759:NHAL RS09990
gene id: 472759:NHAL_RS09990
uniprot id: D5C4H2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

472759:NHAL RS08575
gene id: 472759:NHAL_RS08575
uniprot id: D5C2Z9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

472759:NHAL RS02775
gene id: 472759:NHAL_RS02775
uniprot id: D5BW99
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

472759:NHAL RS05785
gene id: 472759:NHAL_RS05785
uniprot id: D5BZP0
names: Similarity
messages: Belongs to the UPF0045 family.

472759:NHAL RS04170
gene id: 472759:NHAL_RS04170
uniprot id: D5BXR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

472759:NHAL RS11890
gene id: 472759:NHAL_RS11890
uniprot id: D5BVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

472759:NHAL RS19390
gene id: 472759:NHAL_RS19390
uniprot id: D5C5F3
names: Similarity
messages: Belongs to the DNase I family.

472759:NHAL RS19100
gene id: 472759:NHAL_RS19100
uniprot id: D5C411
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

472759:NHAL RS05945
gene id: 472759:NHAL_RS05945
uniprot id: D5BZS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

472759:NHAL RS07480
gene id: 472759:NHAL_RS07480
uniprot id: D5C1P7
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

472759:NHAL RS07860
gene id: 472759:NHAL_RS07860
uniprot id: D5C1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

472759:NHAL RS11100
gene id: 472759:NHAL_RS11100
uniprot id: D5BV21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

472759:NHAL RS09765
gene id: 472759:NHAL_RS09765
uniprot id: D5C4D2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

472759:NHAL RS19170
gene id: 472759:NHAL_RS19170
uniprot id: D5C425
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

472759:NHAL RS06355
gene id: 472759:NHAL_RS06355
uniprot id: D5C0C4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

472759:NHAL RS03510
gene id: 472759:NHAL_RS03510
uniprot id: D5BX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

472759:NHAL RS05950
gene id: 472759:NHAL_RS05950
uniprot id: D5BZS4
names: Similarity
messages: Belongs to the citrate synthase family.

472759:NHAL RS13025
gene id: 472759:NHAL_RS13025
uniprot id: D5BX78
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

472759:NHAL RS00875
gene id: 472759:NHAL_RS00875
uniprot id: D5C4W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

472759:NHAL RS19125
gene id: 472759:NHAL_RS19125
uniprot id: D5C416
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS07295
gene id: 472759:NHAL_RS07295
uniprot id: D5C1K9
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

472759:NHAL RS14725
gene id: 472759:NHAL_RS14725
uniprot id: D5BZ77
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

472759:NHAL RS02830
gene id: 472759:NHAL_RS02830
uniprot id: D5BWB0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS13660
gene id: 472759:NHAL_RS13660
uniprot id: D5BXX1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS00895
gene id: 472759:NHAL_RS00895
uniprot id: D5C4W6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

472759:NHAL RS06155
gene id: 472759:NHAL_RS06155
uniprot id: D5C086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

472759:NHAL RS05415
gene id: 472759:NHAL_RS05415
uniprot id: D5BZ59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

472759:NHAL RS14050
gene id: 472759:NHAL_RS14050
uniprot id: D5BYH5
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

472759:NHAL RS18545
gene id: 472759:NHAL_RS18545
uniprot id: D5C3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

472759:NHAL RS02575
gene id: 472759:NHAL_RS02575
uniprot id: D5BW59
names: Similarity
messages: Belongs to the UPF0434 family.

472759:NHAL RS17285
gene id: 472759:NHAL_RS17285
uniprot id: D5C1Z9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

472759:NHAL RS01925
gene id: 472759:NHAL_RS01925
uniprot id: D5BVF8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

472759:NHAL RS18225
gene id: 472759:NHAL_RS18225
uniprot id: D5C2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

472759:NHAL RS18515
gene id: 472759:NHAL_RS18515
uniprot id: D5C3C5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

472759:NHAL RS16850
gene id: 472759:NHAL_RS16850
uniprot id: D5C1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS05940
gene id: 472759:NHAL_RS05940
uniprot id: D5BZS2
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS13560
gene id: 472759:NHAL_RS13560
uniprot id: D5BXV2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

472759:NHAL RS14055
gene id: 472759:NHAL_RS14055
uniprot id: D5BYH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

472759:NHAL RS18490
gene id: 472759:NHAL_RS18490
uniprot id: D5C3C0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

472759:NHAL RS00275
gene id: 472759:NHAL_RS00275
uniprot id: D5C487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

472759:NHAL RS17010
gene id: 472759:NHAL_RS17010
uniprot id: D5C1H8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

472759:NHAL RS03170
gene id: 472759:NHAL_RS03170
uniprot id: D5BWU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

472759:NHAL RS11685
gene id: 472759:NHAL_RS11685
uniprot id: D5BVQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

472759:NHAL RS05195
gene id: 472759:NHAL_RS05195
uniprot id: D5BZ16
names: Similarity
messages: Belongs to the UPF0047 family.

472759:NHAL RS13445
gene id: 472759:NHAL_RS13445
uniprot id: D5BXS9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

472759:NHAL RS04365
gene id: 472759:NHAL_RS04365
uniprot id: D5BY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

472759:NHAL RS06735
gene id: 472759:NHAL_RS06735
uniprot id: D5C0X3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

472759:NHAL RS11550
gene id: 472759:NHAL_RS11550
uniprot id: D5BVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

472759:NHAL RS09555
gene id: 472759:NHAL_RS09555
uniprot id: D5C3V3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS12950
gene id: 472759:NHAL_RS12950
uniprot id: D5BX62
names: Similarity
messages: Belongs to the peptidase S49 family.

472759:NHAL RS16820
gene id: 472759:NHAL_RS16820
uniprot id: D5C1E0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

472759:NHAL RS11335
gene id: 472759:NHAL_RS11335
uniprot id: D5BV71
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

472759:NHAL RS19130
gene id: 472759:NHAL_RS19130
uniprot id: D5C417
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

472759:NHAL RS12675
gene id: 472759:NHAL_RS12675
uniprot id: D5BWN2
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11060
gene id: 472759:NHAL_RS11060
uniprot id: D5BV13
names: Similarity
messages: Belongs to the ClpA/ClpB family.

472759:NHAL RS10110
gene id: 472759:NHAL_RS10110
uniprot id: D5C4J6
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

472759:NHAL RS10900
gene id: 472759:NHAL_RS10900
uniprot id: D5C5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

472759:NHAL RS05270
gene id: 472759:NHAL_RS05270
uniprot id: D5BZ30
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

472759:NHAL RS13480
gene id: 472759:NHAL_RS13480
uniprot id: D5BXT6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

472759:NHAL RS09785
gene id: 472759:NHAL_RS09785
uniprot id: D5C4D6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

472759:NHAL RS09355
gene id: 472759:NHAL_RS09355
uniprot id: D5C3R4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

472759:NHAL RS03215
gene id: 472759:NHAL_RS03215
uniprot id: D5BWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

472759:NHAL RS04190
gene id: 472759:NHAL_RS04190
uniprot id: D5BXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

472759:NHAL RS19200
gene id: 472759:NHAL_RS19200
uniprot id: D5C431
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS15045
gene id: 472759:NHAL_RS15045
uniprot id: D5BZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

472759:NHAL RS18815
gene id: 472759:NHAL_RS18815
uniprot id: D5C3I5
names: Similarity
messages: Belongs to the HisA/HisF family.

472759:NHAL RS03465
gene id: 472759:NHAL_RS03465
uniprot id: D5BX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS10390
gene id: 472759:NHAL_RS10390
uniprot id: D5C510
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS13315
gene id: 472759:NHAL_RS13315
uniprot id: D5BXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

472759:NHAL RS03245
gene id: 472759:NHAL_RS03245
uniprot id: D5BWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

472759:NHAL RS17495
gene id: 472759:NHAL_RS17495
uniprot id: D5C242
names: Similarity
messages: Belongs to the MotB family.

472759:NHAL RS17550
gene id: 472759:NHAL_RS17550
uniprot id: D5C253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

472759:NHAL RS00865
gene id: 472759:NHAL_RS00865
uniprot id: D5C4W0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

472759:NHAL RS13080
gene id: 472759:NHAL_RS13080
uniprot id: D5BX90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

472759:NHAL RS17965
gene id: 472759:NHAL_RS17965
uniprot id: D5C2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

472759:NHAL RS02800
gene id: 472759:NHAL_RS02800
uniprot id: D5BWA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

472759:NHAL RS02855
gene id: 472759:NHAL_RS02855
uniprot id: D5BWB6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

472759:NHAL RS15515
gene id: 472759:NHAL_RS15515
uniprot id: D5BZZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

472759:NHAL RS00900
gene id: 472759:NHAL_RS00900
uniprot id: D5C4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

472759:NHAL RS03230
gene id: 472759:NHAL_RS03230
uniprot id: D5BWV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

472759:NHAL RS07600
gene id: 472759:NHAL_RS07600
uniprot id: D5C1R9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

472759:NHAL RS02380
gene id: 472759:NHAL_RS02380
uniprot id: D5BW24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

472759:NHAL RS12110
gene id: 472759:NHAL_RS12110
uniprot id: D5BVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

472759:NHAL RS13120
gene id: 472759:NHAL_RS13120
uniprot id: D5BX98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

472759:NHAL RS04050
gene id: 472759:NHAL_RS04050
uniprot id: D5BXP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

472759:NHAL RS16485
gene id: 472759:NHAL_RS16485
uniprot id: D5C0V5
names: Similarity
messages: Belongs to the LOG family.

472759:NHAL RS11755
gene id: 472759:NHAL_RS11755
uniprot id: D5BVS1
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

472759:NHAL RS13340
gene id: 472759:NHAL_RS13340
uniprot id: D5BXD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

472759:NHAL RS11575
gene id: 472759:NHAL_RS11575
uniprot id: D5BVN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

472759:NHAL RS13730
gene id: 472759:NHAL_RS13730
uniprot id: D5BXY6
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

472759:NHAL RS13945
gene id: 472759:NHAL_RS13945
uniprot id: D5BY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

472759:NHAL RS02080
gene id: 472759:NHAL_RS02080
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS05780
gene id: 472759:NHAL_RS05780
uniprot id: D5BZN9
names: Similarity
messages: Belongs to the peptidase C56 family.

472759:NHAL RS12705
gene id: 472759:NHAL_RS12705
uniprot id: D5BWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS11495
gene id: 472759:NHAL_RS11495
uniprot id: D5BVA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS14735
gene id: 472759:NHAL_RS14735
uniprot id: D5BZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

472759:NHAL RS10730
gene id: 472759:NHAL_RS10730
uniprot id: D5C573
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

472759:NHAL RS02065
gene id: 472759:NHAL_RS02065
uniprot id: D5BVI6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

472759:NHAL RS00090
gene id: 472759:NHAL_RS00090
uniprot id: D5C452
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS16995
gene id: 472759:NHAL_RS16995
uniprot id: D5C1H5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

472759:NHAL RS13170
gene id: 472759:NHAL_RS13170
uniprot id: D5BXA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

472759:NHAL RS13850
gene id: 472759:NHAL_RS13850
uniprot id: D5BY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS03500
gene id: 472759:NHAL_RS03500
uniprot id: D5BX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

472759:NHAL RS18795
gene id: 472759:NHAL_RS18795
uniprot id: D5C3I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

472759:NHAL RS11650
gene id: 472759:NHAL_RS11650
uniprot id: D5BVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

472759:NHAL RS12585
gene id: 472759:NHAL_RS12585
uniprot id: D5BWL4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

472759:NHAL RS15565
gene id: 472759:NHAL_RS15565
uniprot id: D5C009
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

472759:NHAL RS13045
gene id: 472759:NHAL_RS13045
uniprot id: D5BX82
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

472759:NHAL RS11835
gene id: 472759:NHAL_RS11835
uniprot id: D5BVT7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

472759:NHAL RS18895
gene id: 472759:NHAL_RS18895
uniprot id: D5C3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

472759:NHAL RS13135
gene id: 472759:NHAL_RS13135
uniprot id: D5BXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS12755
gene id: 472759:NHAL_RS12755
uniprot id: D5BWQ0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

472759:NHAL RS11815
gene id: 472759:NHAL_RS11815
uniprot id: D5BVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

472759:NHAL RS09645
gene id: 472759:NHAL_RS09645
uniprot id: D5C3X2
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

472759:NHAL RS08785
gene id: 472759:NHAL_RS08785
uniprot id: D5C342
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS10370
gene id: 472759:NHAL_RS10370
uniprot id: D5C506
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

472759:NHAL RS13740
gene id: 472759:NHAL_RS13740
uniprot id: D5BXY8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

472759:NHAL RS04590
gene id: 472759:NHAL_RS04590
uniprot id: D5BYC5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

472759:NHAL RS00175
gene id: 472759:NHAL_RS00175
uniprot id: D5C469
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

472759:NHAL RS19090
gene id: 472759:NHAL_RS19090
uniprot id: D5C409
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

472759:NHAL RS11080
gene id: 472759:NHAL_RS11080
uniprot id: D5BV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS13575
gene id: 472759:NHAL_RS13575
uniprot id: D5BXV5
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

472759:NHAL RS05530
gene id: 472759:NHAL_RS05530
uniprot id: D5BZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

472759:NHAL RS02400
gene id: 472759:NHAL_RS02400
uniprot id: D5BW28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

472759:NHAL RS06050
gene id: 472759:NHAL_RS06050
uniprot id: D5BZU5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

472759:NHAL RS00930
gene id: 472759:NHAL_RS00930
uniprot id: D5C4X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS06370
gene id: 472759:NHAL_RS06370
uniprot id: D5C0C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

472759:NHAL RS00010
gene id: 472759:NHAL_RS00010
uniprot id: D5C436
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

472759:NHAL RS16280
gene id: 472759:NHAL_RS16280
uniprot id: D5C0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS11780
gene id: 472759:NHAL_RS11780
uniprot id: D5BVS6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

472759:NHAL RS05525
gene id: 472759:NHAL_RS05525
uniprot id: D5BZJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS11240
gene id: 472759:NHAL_RS11240
uniprot id: D5BV51
names: Similarity
messages: Belongs to the YciI family.

472759:NHAL RS01580
gene id: 472759:NHAL_RS01580
uniprot id: D5BUW8
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS18745
gene id: 472759:NHAL_RS18745
uniprot id: D5C3H1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

472759:NHAL RS15975
gene id: 472759:NHAL_RS15975
uniprot id: D5C0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

472759:NHAL RS16275
gene id: 472759:NHAL_RS16275
uniprot id: D5C0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

472759:NHAL RS12005
gene id: 472759:NHAL_RS12005
uniprot id: D5BVX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

472759:NHAL RS18280
gene id: 472759:NHAL_RS18280
uniprot id: D5C2V9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

472759:NHAL RS02760
gene id: 472759:NHAL_RS02760
uniprot id: D5BW96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

472759:NHAL RS02595
gene id: 472759:NHAL_RS02595
uniprot id: D5BW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

472759:NHAL RS19070
gene id: 472759:NHAL_RS19070
uniprot id: D5C404
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

472759:NHAL RS17930
gene id: 472759:NHAL_RS17930
uniprot id: D5C2P1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

472759:NHAL RS17365
gene id: 472759:NHAL_RS17365
uniprot id: D5C216
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS02130
gene id: 472759:NHAL_RS02130
uniprot id: D5BVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

472759:NHAL RS19050
gene id: 472759:NHAL_RS19050
uniprot id: D5C400
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

472759:NHAL RS04555
gene id: 472759:NHAL_RS04555
uniprot id: D5BYB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

472759:NHAL RS02850
gene id: 472759:NHAL_RS02850
uniprot id: D5BWB5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

472759:NHAL RS16860
gene id: 472759:NHAL_RS16860
uniprot id: D5C1E8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS03515
gene id: 472759:NHAL_RS03515
uniprot id: D5BX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

472759:NHAL RS11565
gene id: 472759:NHAL_RS11565
uniprot id: D5BVB1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

472759:NHAL RS02825
gene id: 472759:NHAL_RS02825
uniprot id: D5BWA9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

472759:NHAL RS14625
gene id: 472759:NHAL_RS14625
uniprot id: D5BYT8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

472759:NHAL RS11675
gene id: 472759:NHAL_RS11675
uniprot id: D5BVQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

472759:NHAL RS18075
gene id: 472759:NHAL_RS18075
uniprot id: D5C2R9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

472759:NHAL RS15205
gene id: 472759:NHAL_RS15205
uniprot id: D5BZH0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS15105
gene id: 472759:NHAL_RS15105
uniprot id: D5BZE9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS03845
gene id: 472759:NHAL_RS03845
uniprot id: D5BXK5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

472759:NHAL RS12925
gene id: 472759:NHAL_RS12925
uniprot id: D5BX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

472759:NHAL RS02495
gene id: 472759:NHAL_RS02495
uniprot id: D5BW47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS01835
gene id: 472759:NHAL_RS01835
uniprot id: D5BVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

472759:NHAL RS18680
gene id: 472759:NHAL_RS18680
uniprot id: D5C3F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

472759:NHAL RS17850
gene id: 472759:NHAL_RS17850
uniprot id: D5C2M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

472759:NHAL RS09450
gene id: 472759:NHAL_RS09450
uniprot id: D5C3T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

472759:NHAL RS12940
gene id: 472759:NHAL_RS12940
uniprot id: D5BX60
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

472759:NHAL RS05540
gene id: 472759:NHAL_RS05540
uniprot id: D5BZJ7
names: Similarity
messages: Belongs to the aspartokinase family.

472759:NHAL RS12090
gene id: 472759:NHAL_RS12090
uniprot id: D5BVY6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

472759:NHAL RS19165
gene id: 472759:NHAL_RS19165
uniprot id: D5C424
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

472759:NHAL RS03445
gene id: 472759:NHAL_RS03445
uniprot id: D5BX03
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

472759:NHAL RS05680
gene id: 472759:NHAL_RS05680
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS02630
gene id: 472759:NHAL_RS02630
uniprot id: D5BW70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

472759:NHAL RS15070
gene id: 472759:NHAL_RS15070
uniprot id: D5BZE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

472759:NHAL RS10710
gene id: 472759:NHAL_RS10710
uniprot id: D5C569
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

472759:NHAL RS11460
gene id: 472759:NHAL_RS11460
uniprot id: D5BV95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

472759:NHAL RS17950
gene id: 472759:NHAL_RS17950
uniprot id: D5C2P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS11570
gene id: 472759:NHAL_RS11570
uniprot id: D5BVB2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

472759:NHAL RS15935
gene id: 472759:NHAL_RS15935
uniprot id: D5C0K5
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

472759:NHAL RS00825
gene id: 472759:NHAL_RS00825
uniprot id: D5C4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

472759:NHAL RS17895
gene id: 472759:NHAL_RS17895
uniprot id: D5C2N4
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS05285
gene id: 472759:NHAL_RS05285
uniprot id: D5BZ33
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

472759:NHAL RS10030
gene id: 472759:NHAL_RS10030
uniprot id: D5C4I0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16605
gene id: 472759:NHAL_RS16605
uniprot id: D5C198
names: Similarity
messages: Belongs to the AlaDH/PNT family.

472759:NHAL RS03615
gene id: 472759:NHAL_RS03615
uniprot id: D5BXG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

472759:NHAL RS02440
gene id: 472759:NHAL_RS02440
uniprot id: D5BW36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

472759:NHAL RS02920
gene id: 472759:NHAL_RS02920
uniprot id: D5BWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

472759:NHAL RS11795
gene id: 472759:NHAL_RS11795
uniprot id: D5BVS9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

472759:NHAL RS09800
gene id: 472759:NHAL_RS09800
uniprot id: D5C4D9
names: Similarity
messages: Belongs to the GSP E family.

472759:NHAL RS18055
gene id: 472759:NHAL_RS18055
uniprot id: D5C2R5
names: Similarity
messages: Belongs to the thioredoxin family.

472759:NHAL RS17115
gene id: 472759:NHAL_RS17115
uniprot id: D5C1K1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

472759:NHAL RS11265
gene id: 472759:NHAL_RS11265
uniprot id: D5BV56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

472759:NHAL RS07070
gene id: 472759:NHAL_RS07070
uniprot id: D5C143
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS18675
gene id: 472759:NHAL_RS18675
uniprot id: D5C3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

472759:NHAL RS09485
gene id: 472759:NHAL_RS09485
uniprot id: D5C3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

472759:NHAL RS12035
gene id: 472759:NHAL_RS12035
uniprot id: D5BVX7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

472759:NHAL RS11850
gene id: 472759:NHAL_RS11850
uniprot id: D5BVU0
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

472759:NHAL RS16625
gene id: 472759:NHAL_RS16625
uniprot id: D5C1A2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

472759:NHAL RS14020
gene id: 472759:NHAL_RS14020
uniprot id: D5BY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

472759:NHAL RS11145
gene id: 472759:NHAL_RS11145
uniprot id: D5BV31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

472759:NHAL RS14520
gene id: 472759:NHAL_RS14520
uniprot id: D5BYR7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

472759:NHAL RS05535
gene id: 472759:NHAL_RS05535
uniprot id: D5BZJ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

472759:NHAL RS11745
gene id: 472759:NHAL_RS11745
uniprot id: D5BVR9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

472759:NHAL RS07310
gene id: 472759:NHAL_RS07310
uniprot id: D5C1L2
names: Similarity
messages: Belongs to the CapA family.

472759:NHAL RS05990
gene id: 472759:NHAL_RS05990
uniprot id: D5BZT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

472759:NHAL RS16160
gene id: 472759:NHAL_RS16160
uniprot id: D5C0P7
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11325
gene id: 472759:NHAL_RS11325
uniprot id: D5BV69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

472759:NHAL RS17985
gene id: 472759:NHAL_RS17985
uniprot id: D5C2Q1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS11045
gene id: 472759:NHAL_RS11045
uniprot id: D5BV10
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

472759:NHAL RS15135
gene id: 472759:NHAL_RS15135
uniprot id: D5BZF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

472759:NHAL RS15245
gene id: 472759:NHAL_RS15245
uniprot id: D5BZH8
names: Similarity
messages: Belongs to the SCO1/2 family.

472759:NHAL RS00470
gene id: 472759:NHAL_RS00470
uniprot id: D5C4N8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS18850
gene id: 472759:NHAL_RS18850
uniprot id: D5C3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

472759:NHAL RS12890
gene id: 472759:NHAL_RS12890
uniprot id: D5BX50
names: Similarity
messages: Belongs to the MotB family.

472759:NHAL RS15555
gene id: 472759:NHAL_RS15555
uniprot id: D5C007
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

472759:NHAL RS11055
gene id: 472759:NHAL_RS11055
uniprot id: D5BV12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

472759:NHAL RS13855
gene id: 472759:NHAL_RS13855
uniprot id: D5BY12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

472759:NHAL RS10190
gene id: 472759:NHAL_RS10190
uniprot id: D5C4K8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

472759:NHAL RS19610
gene id: 472759:NHAL_RS19610
uniprot id: D5BWU6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

472759:NHAL RS18230
gene id: 472759:NHAL_RS18230
uniprot id: D5C2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

472759:NHAL RS19085
gene id: 472759:NHAL_RS19085
uniprot id: D5C408
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

472759:NHAL RS03190
gene id: 472759:NHAL_RS03190
uniprot id: D5BWV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

472759:NHAL RS02615
gene id: 472759:NHAL_RS02615
uniprot id: D5BW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

472759:NHAL RS14885
gene id: 472759:NHAL_RS14885
uniprot id: D5BZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

472759:NHAL RS16725
gene id: 472759:NHAL_RS16725
uniprot id: D5C1C1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

472759:NHAL RS06070
gene id: 472759:NHAL_RS06070
uniprot id: D5C068
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

472759:NHAL RS16755
gene id: 472759:NHAL_RS16755
uniprot id: D5C1C7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

472759:NHAL RS02700
gene id: 472759:NHAL_RS02700
uniprot id: D5BW84
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

472759:NHAL RS09235
gene id: 472759:NHAL_RS09235
uniprot id: D5C3P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

472759:NHAL RS15075
gene id: 472759:NHAL_RS15075
uniprot id: D5BZE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

472759:NHAL RS03550
gene id: 472759:NHAL_RS03550
uniprot id: D5BX24
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

472759:NHAL RS07010
gene id: 472759:NHAL_RS07010
uniprot id: D5C131
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

472759:NHAL RS04340
gene id: 472759:NHAL_RS04340
uniprot id: D5BY75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS19115
gene id: 472759:NHAL_RS19115
uniprot id: D5C414
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

472759:NHAL RS12265
gene id: 472759:NHAL_RS12265
uniprot id: D5BWE8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

472759:NHAL RS13845
gene id: 472759:NHAL_RS13845
uniprot id: D5BY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS18435
gene id: 472759:NHAL_RS18435
uniprot id: D5C3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

472759:NHAL RS10275
gene id: 472759:NHAL_RS10275
uniprot id: D5C4M6
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03820
gene id: 472759:NHAL_RS03820
uniprot id: D5BXK0
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

472759:NHAL RS15405
gene id: 472759:NHAL_RS15405
uniprot id: D5BZX8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

472759:NHAL RS03375
gene id: 472759:NHAL_RS03375
uniprot id: D5BWY9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

472759:NHAL RS13140
gene id: 472759:NHAL_RS13140
uniprot id: D5BXA3
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16670
gene id: 472759:NHAL_RS16670
uniprot id: D5C1B2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

472759:NHAL RS03370
gene id: 472759:NHAL_RS03370
uniprot id: D5BWY8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

472759:NHAL RS14025
gene id: 472759:NHAL_RS14025
uniprot id: D5BYH0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS13015
gene id: 472759:NHAL_RS13015
uniprot id: D5BX76
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

472759:NHAL RS13585
gene id: 472759:NHAL_RS13585
uniprot id: D5BXV7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

472759:NHAL RS18510
gene id: 472759:NHAL_RS18510
uniprot id: D5C3C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

472759:NHAL RS02790
gene id: 472759:NHAL_RS02790
uniprot id: D5BWA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

472759:NHAL RS13325
gene id: 472759:NHAL_RS13325
uniprot id: D5BXD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

472759:NHAL RS01060
gene id: 472759:NHAL_RS01060
uniprot id: D5C4Z3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

472759:NHAL RS00160
gene id: 472759:NHAL_RS00160
uniprot id: D5C466
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

472759:NHAL RS04325
gene id: 472759:NHAL_RS04325
uniprot id: D5BY72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS04290
gene id: 472759:NHAL_RS04290
uniprot id: D5BY65
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

472759:NHAL RS02655
gene id: 472759:NHAL_RS02655
uniprot id: D5BW75
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

472759:NHAL RS08175
gene id: 472759:NHAL_RS08175
uniprot id: D5C2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

472759:NHAL RS07345
gene id: 472759:NHAL_RS07345
uniprot id: D5C1M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

472759:NHAL RS10800
gene id: 472759:NHAL_RS10800
uniprot id: D5C588
names: Similarity
messages: Belongs to the asparagine synthetase family.

472759:NHAL RS18135
gene id: 472759:NHAL_RS18135
uniprot id: D5C2T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

472759:NHAL RS01815
gene id: 472759:NHAL_RS01815
uniprot id: D5BVD8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

472759:NHAL RS17360
gene id: 472759:NHAL_RS17360
uniprot id: D5C215
names: Similarity
messages: Belongs to the peptidase C40 family.

472759:NHAL RS02895
gene id: 472759:NHAL_RS02895
uniprot id: D5BWC4
names: Similarity
messages: Belongs to the P(II) protein family.

472759:NHAL RS11510
gene id: 472759:NHAL_RS11510
uniprot id: D5BVA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

472759:NHAL RS19195
gene id: 472759:NHAL_RS19195
uniprot id: D5C430
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

472759:NHAL RS02470
gene id: 472759:NHAL_RS02470
uniprot id: D5BW42
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

472759:NHAL RS04330
gene id: 472759:NHAL_RS04330
uniprot id: D5BY73
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

472759:NHAL RS11760
gene id: 472759:NHAL_RS11760
uniprot id: D5BVS2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

472759:NHAL RS03850
gene id: 472759:NHAL_RS03850
uniprot id: D5BXK6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

472759:NHAL RS10080
gene id: 472759:NHAL_RS10080
uniprot id: D5C4J0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

472759:NHAL RS13070
gene id: 472759:NHAL_RS13070
uniprot id: D5BX87
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS07290
gene id: 472759:NHAL_RS07290
uniprot id: D5C1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm

472759:NHAL RS06145
gene id: 472759:NHAL_RS06145
uniprot id: D5C083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

472759:NHAL RS11860
gene id: 472759:NHAL_RS11860
uniprot id: D5BVU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

472759:NHAL RS12885
gene id: 472759:NHAL_RS12885
uniprot id: D5BX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

472759:NHAL RS00880
gene id: 472759:NHAL_RS00880
uniprot id: D5C4W3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

472759:NHAL RS06305
gene id: 472759:NHAL_RS06305
uniprot id: D5C0B4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

472759:NHAL RS11130
gene id: 472759:NHAL_RS11130
uniprot id: D5BV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS21740
gene id: 472759:NHAL_RS21740
uniprot id: D5BXG9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

472759:NHAL RS11530
gene id: 472759:NHAL_RS11530
uniprot id: D5BVA8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

472759:NHAL RS19420
gene id: 472759:NHAL_RS19420
uniprot id: D5C5F9
names: Similarity
messages: Belongs to the ParB family.

472759:NHAL RS10820
gene id: 472759:NHAL_RS10820
uniprot id: D5C593
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

472759:NHAL RS14615
gene id: 472759:NHAL_RS14615
uniprot id: D5BYT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

472759:NHAL RS19025
gene id: 472759:NHAL_RS19025
uniprot id: D5C3Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

472759:NHAL RS07125
gene id: 472759:NHAL_RS07125
uniprot id: D5C155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

472759:NHAL RS02265
gene id: 472759:NHAL_RS02265
uniprot id: D5BVM3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

472759:NHAL RS06055
gene id: 472759:NHAL_RS06055
uniprot id: D5BZU6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

472759:NHAL RS12520
gene id: 472759:NHAL_RS12520
uniprot id: D5BWK0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS14410
gene id: 472759:NHAL_RS14410
uniprot id: D5BYP4
names: Similarity
messages: Belongs to the pyruvate kinase family.

472759:NHAL RS13300
gene id: 472759:NHAL_RS13300
uniprot id: D5BXC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

472759:NHAL RS17475
gene id: 472759:NHAL_RS17475
uniprot id: D5C238
names: Similarity
messages: Belongs to the MEMO1 family.

472759:NHAL RS05040
gene id: 472759:NHAL_RS05040
uniprot id: D5BYY8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

472759:NHAL RS17710
gene id: 472759:NHAL_RS17710
uniprot id: D5C287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS18285
gene id: 472759:NHAL_RS18285
uniprot id: D5C2W0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

472759:NHAL RS09205
gene id: 472759:NHAL_RS09205
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS00060
gene id: 472759:NHAL_RS00060
uniprot id: D5C446
names: Similarity
messages: Belongs to the FwdC/FmdC family.

472759:NHAL RS02785
gene id: 472759:NHAL_RS02785
uniprot id: D5BWA1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

472759:NHAL RS02640
gene id: 472759:NHAL_RS02640
uniprot id: D5BW72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

472759:NHAL RS16710
gene id: 472759:NHAL_RS16710
uniprot id: D5C1B8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

472759:NHAL RS02345
gene id: 472759:NHAL_RS02345
uniprot id: D5BW17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

472759:NHAL RS09090
gene id: 472759:NHAL_RS09090
uniprot id: D5C3M0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

472759:NHAL RS01720
gene id: 472759:NHAL_RS01720
uniprot id: D5BVB9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

472759:NHAL RS11500
gene id: 472759:NHAL_RS11500
uniprot id: D5BVA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS04235
gene id: 472759:NHAL_RS04235
uniprot id: D5BY53
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

472759:NHAL RS18670
gene id: 472759:NHAL_RS18670
uniprot id: D5C3F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

472759:NHAL RS00065
gene id: 472759:NHAL_RS00065
uniprot id: D5C447
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

472759:NHAL RS13395
gene id: 472759:NHAL_RS13395
uniprot id: D5BXE8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS05955
gene id: 472759:NHAL_RS05955
uniprot id: D5BZS5
names: Similarity
messages: Belongs to the PrpD family.

472759:NHAL RS14580
gene id: 472759:NHAL_RS14580
uniprot id: D5BYS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

472759:NHAL RS12030
gene id: 472759:NHAL_RS12030
uniprot id: D5BVX6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

472759:NHAL RS11135
gene id: 472759:NHAL_RS11135
uniprot id: D5BV29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS09640
gene id: 472759:NHAL_RS09640
uniprot id: D5C3X1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

472759:NHAL RS03780
gene id: 472759:NHAL_RS03780
uniprot id: D5BXJ2
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

472759:NHAL RS04285
gene id: 472759:NHAL_RS04285
uniprot id: D5BY64
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS03165
gene id: 472759:NHAL_RS03165
uniprot id: D5BWU4
names: Similarity
messages: Belongs to the MT-A70-like family.

472759:NHAL RS18140
gene id: 472759:NHAL_RS18140
uniprot id: D5C2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

472759:NHAL RS16560
gene id: 472759:NHAL_RS16560
uniprot id: D5C188
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

472759:NHAL RS11885
gene id: 472759:NHAL_RS11885
uniprot id: D5BVU7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

472759:NHAL RS02425
gene id: 472759:NHAL_RS02425
uniprot id: D5BW33
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

472759:NHAL RS12135
gene id: 472759:NHAL_RS12135
uniprot id: D5BVZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

472759:NHAL RS18115
gene id: 472759:NHAL_RS18115
uniprot id: D5C2S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

472759:NHAL RS06845
gene id: 472759:NHAL_RS06845
uniprot id: D5C0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS17400
gene id: 472759:NHAL_RS17400
uniprot id: D5C223
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS10220
gene id: 472759:NHAL_RS10220
uniprot id: D5C4L4
names: Similarity
messages: Belongs to the YkuD family.

472759:NHAL RS12835
gene id: 472759:NHAL_RS12835
uniprot id: D5BX40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS12855
gene id: 472759:NHAL_RS12855
uniprot id: D5BX43
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

472759:NHAL RS11930
gene id: 472759:NHAL_RS11930
uniprot id: D5BVV6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

472759:NHAL RS16745
gene id: 472759:NHAL_RS16745
uniprot id: D5C1C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

472759:NHAL RS19010
gene id: 472759:NHAL_RS19010
uniprot id: D5C3Z3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

472759:NHAL RS01270
gene id: 472759:NHAL_RS01270
uniprot id: D5BUQ3
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

472759:NHAL RS00610
gene id: 472759:NHAL_RS00610
uniprot id: D5C4R5
names: Similarity
messages: Belongs to the YoeB family.

472759:NHAL RS13125
gene id: 472759:NHAL_RS13125
uniprot id: D5BX99
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

472759:NHAL RS03235
gene id: 472759:NHAL_RS03235
uniprot id: D5BWV9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

472759:NHAL RS12330
gene id: 472759:NHAL_RS12330
uniprot id: D5BWG0
names: Similarity
messages: Belongs to the PhoH family.

472759:NHAL RS18590
gene id: 472759:NHAL_RS18590
uniprot id: D5C3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS03405
gene id: 472759:NHAL_RS03405
uniprot id: D5BWZ5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

472759:NHAL RS08810
gene id: 472759:NHAL_RS08810
uniprot id: D5C347
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

472759:NHAL RS17785
gene id: 472759:NHAL_RS17785
uniprot id: D5C2L4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

472759:NHAL RS17995
gene id: 472759:NHAL_RS17995
uniprot id: D5C2Q3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

472759:NHAL RS11560
gene id: 472759:NHAL_RS11560
uniprot id: D5BVB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS02310
gene id: 472759:NHAL_RS02310
uniprot id: D5BVN2
names: Similarity
messages: Belongs to the UPF0102 family.

472759:NHAL RS00600
gene id: 472759:NHAL_RS00600
uniprot id: D5C4R4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

472759:NHAL RS05825
gene id: 472759:NHAL_RS05825
uniprot id: D5BZP8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS18555
gene id: 472759:NHAL_RS18555
uniprot id: D5C3D3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

472759:NHAL RS01150
gene id: 472759:NHAL_RS01150
uniprot id: D5BUN3
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

472759:NHAL RS00285
gene id: 472759:NHAL_RS00285
uniprot id: D5C489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

472759:NHAL RS11525
gene id: 472759:NHAL_RS11525
uniprot id: D5BVA7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

472759:NHAL RS15460
gene id: 472759:NHAL_RS15460
uniprot id: D5BZY8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

472759:NHAL RS16285
gene id: 472759:NHAL_RS16285
uniprot id: D5C0R8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS18355
gene id: 472759:NHAL_RS18355
uniprot id: D5C393
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

472759:NHAL RS09805
gene id: 472759:NHAL_RS09805
uniprot id: D5C4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS17990
gene id: 472759:NHAL_RS17990
uniprot id: D5C2Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

472759:NHAL RS10010
gene id: 472759:NHAL_RS10010
uniprot id: D5C4H6
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS18630
gene id: 472759:NHAL_RS18630
uniprot id: D5C3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

472759:NHAL RS18290
gene id: 472759:NHAL_RS18290
uniprot id: D5C2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

472759:NHAL RS17855
gene id: 472759:NHAL_RS17855
uniprot id: D5C2M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

472759:NHAL RS02375
gene id: 472759:NHAL_RS02375
uniprot id: D5BW23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS04595
gene id: 472759:NHAL_RS04595
uniprot id: D5BYC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS17260
gene id: 472759:NHAL_RS17260
uniprot id: D5C1Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

472759:NHAL RS17040
gene id: 472759:NHAL_RS17040
uniprot id: D5C1I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

472759:NHAL RS06460
gene id: 472759:NHAL_RS06460
uniprot id: D5C0E6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

472759:NHAL RS04550
gene id: 472759:NHAL_RS04550
uniprot id: D5BYB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

472759:NHAL RS00615
gene id: 472759:NHAL_RS00615
uniprot id: D5C4R6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

472759:NHAL RS00515
gene id: 472759:NHAL_RS00515
uniprot id: D5C4P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

472759:NHAL RS14325
gene id: 472759:NHAL_RS14325
uniprot id: D5BYM7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

472759:NHAL RS13320
gene id: 472759:NHAL_RS13320
uniprot id: D5BXD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

472759:NHAL RS09960
gene id: 472759:NHAL_RS09960
uniprot id: D5C4G9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

472759:NHAL RS16475
gene id: 472759:NHAL_RS16475
uniprot id: D5C0V3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

472759:NHAL RS17790
gene id: 472759:NHAL_RS17790
uniprot id: D5C2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS16865
gene id: 472759:NHAL_RS16865
uniprot id: D5C1E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

472759:NHAL RS10795
gene id: 472759:NHAL_RS10795
uniprot id: D5C587
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

472759:NHAL RS15725
gene id: 472759:NHAL_RS15725
uniprot id: D5C038
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

472759:NHAL RS06250
gene id: 472759:NHAL_RS06250
uniprot id: D5C0A1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

472759:NHAL RS09365
gene id: 472759:NHAL_RS09365
uniprot id: D5C3R6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS08870
gene id: 472759:NHAL_RS08870
uniprot id: D5C359
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS18045
gene id: 472759:NHAL_RS18045
uniprot id: D5C2R3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

472759:NHAL RS12760
gene id: 472759:NHAL_RS12760
uniprot id: D5BWQ1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

472759:NHAL RS03080
gene id: 472759:NHAL_RS03080
uniprot id: D5BWT0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS02820
gene id: 472759:NHAL_RS02820
uniprot id: D5BWA8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

472759:NHAL RS13630
gene id: 472759:NHAL_RS13630
uniprot id: D5BXW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

472759:NHAL RS01645
gene id: 472759:NHAL_RS01645
uniprot id: D5BUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

472759:NHAL RS09580
gene id: 472759:NHAL_RS09580
uniprot id: D5C3V8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

472759:NHAL RS11985
gene id: 472759:NHAL_RS11985
uniprot id: D5BVW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS13450
gene id: 472759:NHAL_RS13450
uniprot id: D5BXT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

472759:NHAL RS07510
gene id: 472759:NHAL_RS07510
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS10590
gene id: 472759:NHAL_RS10590
uniprot id: D5C550
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS06440
gene id: 472759:NHAL_RS06440
uniprot id: D5C0E1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11925
gene id: 472759:NHAL_RS11925
uniprot id: D5BVV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

472759:NHAL RS04605
gene id: 472759:NHAL_RS04605
uniprot id: D5BYC8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS09115
gene id: 472759:NHAL_RS09115
uniprot id: D5C3M5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

472759:NHAL RS03415
gene id: 472759:NHAL_RS03415
uniprot id: D5BWZ7
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS14270
gene id: 472759:NHAL_RS14270
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS01050
gene id: 472759:NHAL_RS01050
uniprot id: D5C4Z1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

472759:NHAL RS00755
gene id: 472759:NHAL_RS00755
uniprot id: D5C4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS03545
gene id: 472759:NHAL_RS03545
uniprot id: D5BX23
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS12670
gene id: 472759:NHAL_RS12670
uniprot id: D5BWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS01810
gene id: 472759:NHAL_RS01810
uniprot id: D5BVD7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS18035
gene id: 472759:NHAL_RS18035
uniprot id: D5C2R1
names: Similarity
messages: Belongs to the peptidase M24B family.

472759:NHAL RS11665
gene id: 472759:NHAL_RS11665
uniprot id: D5BVQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

472759:NHAL RS02150
gene id: 472759:NHAL_RS02150
uniprot id: D5BVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

472759:NHAL RS16190
gene id: 472759:NHAL_RS16190
uniprot id: D5C0Q0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS13410
gene id: 472759:NHAL_RS13410
uniprot id: D5BXS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

472759:NHAL RS06975
gene id: 472759:NHAL_RS06975
uniprot id: D5C124
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS18480
gene id: 472759:NHAL_RS18480
uniprot id: D5C3B8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS11845
gene id: 472759:NHAL_RS11845
uniprot id: D5BVT9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

472759:NHAL RS10875
gene id: 472759:NHAL_RS10875
uniprot id: D5C5A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

472759:NHAL RS08120
gene id: 472759:NHAL_RS08120
uniprot id: D5C2E2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS05490
gene id: 472759:NHAL_RS05490
uniprot id: D5BZI8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

472759:NHAL RS11785
gene id: 472759:NHAL_RS11785
uniprot id: D5BVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS00360
gene id: 472759:NHAL_RS00360
uniprot id: D5C4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

472759:NHAL RS14825
gene id: 472759:NHAL_RS14825
uniprot id: D5BZ98
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

472759:NHAL RS02540
gene id: 472759:NHAL_RS02540
uniprot id: D5BW52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

472759:NHAL RS08015
gene id: 472759:NHAL_RS08015
uniprot id: D5C2C2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS03035
gene id: 472759:NHAL_RS03035
uniprot id: D5BWS1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS09525
gene id: 472759:NHAL_RS09525
uniprot id: D5C3U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

472759:NHAL RS02450
gene id: 472759:NHAL_RS02450
uniprot id: D5BW38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

472759:NHAL RS17245
gene id: 472759:NHAL_RS17245
uniprot id: D5C1Z1
names: Similarity
messages: Belongs to the CutA family.

472759:NHAL RS10365
gene id: 472759:NHAL_RS10365
uniprot id: D5C505
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS16395
gene id: 472759:NHAL_RS16395
uniprot id: D5C0T7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS09225
gene id: 472759:NHAL_RS09225
uniprot id: D5C3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

472759:NHAL RS16735
gene id: 472759:NHAL_RS16735
uniprot id: D5C1C3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

472759:NHAL RS04360
gene id: 472759:NHAL_RS04360
uniprot id: D5BY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

472759:NHAL RS02975
gene id: 472759:NHAL_RS02975
uniprot id: D5BWQ9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

472759:NHAL RS11840
gene id: 472759:NHAL_RS11840
uniprot id: D5BVT8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

472759:NHAL RS04205
gene id: 472759:NHAL_RS04205
uniprot id: D5BY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

472759:NHAL RS11340
gene id: 472759:NHAL_RS11340
uniprot id: D5BV72
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

472759:NHAL RS06510
gene id: 472759:NHAL_RS06510
uniprot id: D5C0F7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS02835
gene id: 472759:NHAL_RS02835
uniprot id: D5BWB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

472759:NHAL RS12145
gene id: 472759:NHAL_RS12145
uniprot id: D5BVZ7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

472759:NHAL RS06435
gene id: 472759:NHAL_RS06435
uniprot id: D5C0E0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

472759:NHAL RS04505
gene id: 472759:NHAL_RS04505
uniprot id: D5BYA8
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

472759:NHAL RS18500
gene id: 472759:NHAL_RS18500
uniprot id: D5C3C2
names: Similarity
messages: Belongs to the DprA/Smf family.

472759:NHAL RS10050
gene id: 472759:NHAL_RS10050
uniprot id: D5C4I4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

472759:NHAL RS18935
gene id: 472759:NHAL_RS18935
uniprot id: D5C3K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS05275
gene id: 472759:NHAL_RS05275
uniprot id: D5BZ31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

472759:NHAL RS00055
gene id: 472759:NHAL_RS00055
uniprot id: D5C445
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS01110
gene id: 472759:NHAL_RS01110
uniprot id: D5BUM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS14340
gene id: 472759:NHAL_RS14340
uniprot id: D5BYN0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

472759:NHAL RS17395
gene id: 472759:NHAL_RS17395
uniprot id: D5C222
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

472759:NHAL RS14070
gene id: 472759:NHAL_RS14070
uniprot id: D5BYH9
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS00315
gene id: 472759:NHAL_RS00315
uniprot id: D5C494
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

472759:NHAL RS11790
gene id: 472759:NHAL_RS11790
uniprot id: D5BVS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

472759:NHAL RS19790
gene id: 472759:NHAL_RS19790
uniprot id: D5C307
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

472759:NHAL RS11995
gene id: 472759:NHAL_RS11995
uniprot id: D5BVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

472759:NHAL RS02635
gene id: 472759:NHAL_RS02635
uniprot id: D5BW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

472759:NHAL RS18625
gene id: 472759:NHAL_RS18625
uniprot id: D5C3E5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS08950
gene id: 472759:NHAL_RS08950
uniprot id: D5C357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS17975
gene id: 472759:NHAL_RS17975
uniprot id: D5C2P9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

472759:NHAL RS01375
gene id: 472759:NHAL_RS01375
uniprot id: D5BUS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

472759:NHAL RS15200
gene id: 472759:NHAL_RS15200
uniprot id: D5BZG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

472759:NHAL RS09265
gene id: 472759:NHAL_RS09265
uniprot id: D5C3P9
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11690
gene id: 472759:NHAL_RS11690
uniprot id: D5BVQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

472759:NHAL RS04140
gene id: 472759:NHAL_RS04140
uniprot id: D5BXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS03630
gene id: 472759:NHAL_RS03630
uniprot id: D5BXG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

472759:NHAL RS14355
gene id: 472759:NHAL_RS14355
uniprot id: D5BYN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

472759:NHAL RS07255
gene id: 472759:NHAL_RS07255
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS09350
gene id: 472759:NHAL_RS09350
uniprot id: D5C3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS18400
gene id: 472759:NHAL_RS18400
uniprot id: D5C3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

472759:NHAL RS03755
gene id: 472759:NHAL_RS03755
uniprot id: D5BXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

472759:NHAL RS18650
gene id: 472759:NHAL_RS18650
uniprot id: D5C3F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

472759:NHAL RS18205
gene id: 472759:NHAL_RS18205
uniprot id: D5C2U3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

472759:NHAL RS18395
gene id: 472759:NHAL_RS18395
uniprot id: D5C3A1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

472759:NHAL RS10455
gene id: 472759:NHAL_RS10455
uniprot id: D5C523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

472759:NHAL RS09380
gene id: 472759:NHAL_RS09380
uniprot id: D5C3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

472759:NHAL RS12015
gene id: 472759:NHAL_RS12015
uniprot id: D5BVX3
names: Similarity
messages: Belongs to the YfgM family.

472759:NHAL RS11315
gene id: 472759:NHAL_RS11315
uniprot id: D5BV67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

472759:NHAL RS11050
gene id: 472759:NHAL_RS11050
uniprot id: D5BV11
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

472759:NHAL RS11655
gene id: 472759:NHAL_RS11655
uniprot id: D5BVQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

472759:NHAL RS15960
gene id: 472759:NHAL_RS15960
uniprot id: D5C0L0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

472759:NHAL RS08540
gene id: 472759:NHAL_RS08540
uniprot id: D5C2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

472759:NHAL RS03760
gene id: 472759:NHAL_RS03760
uniprot id: D5BXI9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

472759:NHAL RS18605
gene id: 472759:NHAL_RS18605
uniprot id: D5C3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

472759:NHAL RS08705
gene id: 472759:NHAL_RS08705
uniprot id: D5C325
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

472759:NHAL RS11270
gene id: 472759:NHAL_RS11270
uniprot id: D5BV58
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

472759:NHAL RS09270
gene id: 472759:NHAL_RS09270
uniprot id: D5C3Q0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11980
gene id: 472759:NHAL_RS11980
uniprot id: D5BVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

472759:NHAL RS00520
gene id: 472759:NHAL_RS00520
uniprot id: D5C4P8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

472759:NHAL RS02610
gene id: 472759:NHAL_RS02610
uniprot id: D5BW66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

472759:NHAL RS03220
gene id: 472759:NHAL_RS03220
uniprot id: D5BWV6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS03840
gene id: 472759:NHAL_RS03840
uniprot id: D5BXK4
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

472759:NHAL RS13305
gene id: 472759:NHAL_RS13305
uniprot id: D5BXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

472759:NHAL RS14250
gene id: 472759:NHAL_RS14250
uniprot id: D5BYL4
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

472759:NHAL RS07380
gene id: 472759:NHAL_RS07380
uniprot id: D5C1M7
names: Similarity
messages: Belongs to the MlaA family.

472759:NHAL RS16140
gene id: 472759:NHAL_RS16140
uniprot id: D5C0P3
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16775
gene id: 472759:NHAL_RS16775
uniprot id: D5C1D1
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

472759:NHAL RS18095
gene id: 472759:NHAL_RS18095
uniprot id: D5C2S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

472759:NHAL RS00490
gene id: 472759:NHAL_RS00490
uniprot id: D5C4P2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

472759:NHAL RS03430
gene id: 472759:NHAL_RS03430
uniprot id: D5BX00
names: Similarity
messages: Belongs to the asparagine synthetase family.

472759:NHAL RS15505
gene id: 472759:NHAL_RS15505
uniprot id: D5BZZ6
names: Similarity
messages: Belongs to the UPF0047 family.

472759:NHAL RS06465
gene id: 472759:NHAL_RS06465
uniprot id: D5C0E7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

472759:NHAL RS19175
gene id: 472759:NHAL_RS19175
uniprot id: D5C426
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS08375
gene id: 472759:NHAL_RS08375
uniprot id: D5C2J4
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS05980
gene id: 472759:NHAL_RS05980
uniprot id: D5BZT0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

472759:NHAL RS17945
gene id: 472759:NHAL_RS17945
uniprot id: D5C2P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS19995
gene id: 472759:NHAL_RS19995
uniprot id: D5C5B9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

472759:NHAL RS04890
gene id: 472759:NHAL_RS04890
uniprot id: D5BYV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

472759:NHAL RS09825
gene id: 472759:NHAL_RS09825
uniprot id: D5C4E4
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

472759:NHAL RS18910
gene id: 472759:NHAL_RS18910
uniprot id: D5C3K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

472759:NHAL RS00150
gene id: 472759:NHAL_RS00150
uniprot id: D5C464
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

472759:NHAL RS00240
gene id: 472759:NHAL_RS00240
uniprot id: D5C480
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

472759:NHAL RS19210
gene id: 472759:NHAL_RS19210
uniprot id: D5C433
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

472759:NHAL RS00450
gene id: 472759:NHAL_RS00450
uniprot id: D5C4B9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

472759:NHAL RS03985
gene id: 472759:NHAL_RS03985
uniprot id: D5BXN0
names: Similarity
messages: Belongs to the RNase T2 family.

472759:NHAL RS10170
gene id: 472759:NHAL_RS10170
uniprot id: D5C4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

472759:NHAL RS15125
gene id: 472759:NHAL_RS15125
uniprot id: D5BZF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

472759:NHAL RS11900
gene id: 472759:NHAL_RS11900
uniprot id: D5BVV0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

472759:NHAL RS00250
gene id: 472759:NHAL_RS00250
uniprot id: D5C482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

472759:NHAL RS10805
gene id: 472759:NHAL_RS10805
uniprot id: D5C589
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

472759:NHAL RS05180
gene id: 472759:NHAL_RS05180
uniprot id: D5BZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS12980
gene id: 472759:NHAL_RS12980
uniprot id: D5BX69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

472759:NHAL RS10130
gene id: 472759:NHAL_RS10130
uniprot id: D5C4J9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS04700
gene id: 472759:NHAL_RS04700
uniprot id: D5BVG3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS10055
gene id: 472759:NHAL_RS10055
uniprot id: D5C4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

472759:NHAL RS01705
gene id: 472759:NHAL_RS01705
uniprot id: D5BVB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS13460
gene id: 472759:NHAL_RS13460
uniprot id: D5BXT2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

472759:NHAL RS16970
gene id: 472759:NHAL_RS16970
uniprot id: D5C1H0
names: Subcellular Location Annotation
messages: Cytoplasm

472759:NHAL RS03485
gene id: 472759:NHAL_RS03485
uniprot id: D5BX11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

472759:NHAL RS13490
gene id: 472759:NHAL_RS13490
uniprot id: D5BXT8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

472759:NHAL RS12385
gene id: 472759:NHAL_RS12385
uniprot id: D5BWH3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

472759:NHAL RS10375
gene id: 472759:NHAL_RS10375
uniprot id: D5C507
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS17530
gene id: 472759:NHAL_RS17530
uniprot id: D5C249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

472759:NHAL RS18260
gene id: 472759:NHAL_RS18260
uniprot id: D5C2V5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS19065
gene id: 472759:NHAL_RS19065
uniprot id: D5C403
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

472759:NHAL RS05145
gene id: 472759:NHAL_RS05145
uniprot id: D5BZ07
names: Similarity
messages: Belongs to the peptidase S16 family.

472759:NHAL RS10775
gene id: 472759:NHAL_RS10775
uniprot id: D5C583
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS11670
gene id: 472759:NHAL_RS11670
uniprot id: D5BVQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

472759:NHAL RS00935
gene id: 472759:NHAL_RS00935
uniprot id: D5C4X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

472759:NHAL RS13145
gene id: 472759:NHAL_RS13145
uniprot id: D5BXA4
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16220
gene id: 472759:NHAL_RS16220
uniprot id: D5C0Q5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

472759:NHAL RS09175
gene id: 472759:NHAL_RS09175
uniprot id: D5C3N6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

472759:NHAL RS11660
gene id: 472759:NHAL_RS11660
uniprot id: D5BVQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

472759:NHAL RS17555
gene id: 472759:NHAL_RS17555
uniprot id: D5C254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

472759:NHAL RS17560
gene id: 472759:NHAL_RS17560
uniprot id: D5C255
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

472759:NHAL RS12170
gene id: 472759:NHAL_RS12170
uniprot id: D5BW04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

472759:NHAL RS03830
gene id: 472759:NHAL_RS03830
uniprot id: D5BXK2
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS11640
gene id: 472759:NHAL_RS11640
uniprot id: D5BVP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

472759:NHAL RS16630
gene id: 472759:NHAL_RS16630
uniprot id: D5C1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

472759:NHAL RS14745
gene id: 472759:NHAL_RS14745
uniprot id: D5BZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

472759:NHAL RS05810
gene id: 472759:NHAL_RS05810
uniprot id: D5BZP5
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16450
gene id: 472759:NHAL_RS16450
uniprot id: D5C0U7
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS12475
gene id: 472759:NHAL_RS12475
uniprot id: D5BWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS15945
gene id: 472759:NHAL_RS15945
uniprot id: D5C0K7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

472759:NHAL RS17110
gene id: 472759:NHAL_RS17110
uniprot id: D5C1K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

472759:NHAL RS12945
gene id: 472759:NHAL_RS12945
uniprot id: D5BX61
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

472759:NHAL RS19145
gene id: 472759:NHAL_RS19145
uniprot id: D5C420
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

472759:NHAL RS17915
gene id: 472759:NHAL_RS17915
uniprot id: D5C2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

472759:NHAL RS19095
gene id: 472759:NHAL_RS19095
uniprot id: D5C410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

472759:NHAL RS06130
gene id: 472759:NHAL_RS06130
uniprot id: D5C080
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

472759:NHAL RS13130
gene id: 472759:NHAL_RS13130
uniprot id: D5BXA1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS08195
gene id: 472759:NHAL_RS08195
uniprot id: D5C2F7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

472759:NHAL RS01055
gene id: 472759:NHAL_RS01055
uniprot id: D5C4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

472759:NHAL RS11935
gene id: 472759:NHAL_RS11935
uniprot id: D5BVV7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

472759:NHAL RS10735
gene id: 472759:NHAL_RS10735
uniprot id: D5C574
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

472759:NHAL RS00140
gene id: 472759:NHAL_RS00140
uniprot id: D5C462
names: Subcellular Location Annotation
messages: Mitochondrion

472759:NHAL RS16470
gene id: 472759:NHAL_RS16470
uniprot id: D5C0V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

472759:NHAL RS05370
gene id: 472759:NHAL_RS05370
uniprot id: D5BZ50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

472759:NHAL RS12635
gene id: 472759:NHAL_RS12635
uniprot id: D5BWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

472759:NHAL RS10880
gene id: 472759:NHAL_RS10880
uniprot id: D5C5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

472759:NHAL RS05225
gene id: 472759:NHAL_RS05225
uniprot id: D5BZ22
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

472759:NHAL RS00890
gene id: 472759:NHAL_RS00890
uniprot id: D5C4W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

472759:NHAL RS01100
gene id: 472759:NHAL_RS01100
uniprot id: D5BUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

472759:NHAL RS16705
gene id: 472759:NHAL_RS16705
uniprot id: D5C1B7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

472759:NHAL RS18000
gene id: 472759:NHAL_RS18000
uniprot id: D5C2Q4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS08820
gene id: 472759:NHAL_RS08820
uniprot id: D5C349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS02900
gene id: 472759:NHAL_RS02900
uniprot id: D5BWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

472759:NHAL RS04305
gene id: 472759:NHAL_RS04305
uniprot id: D5BY68
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS00980
gene id: 472759:NHAL_RS00980
uniprot id: D5C4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

472759:NHAL RS11600
gene id: 472759:NHAL_RS11600
uniprot id: D5BVN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

472759:NHAL RS02530
gene id: 472759:NHAL_RS02530
uniprot id: D5BW50
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

472759:NHAL RS01070
gene id: 472759:NHAL_RS01070
uniprot id: D5C4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

472759:NHAL RS04575
gene id: 472759:NHAL_RS04575
uniprot id: D5BYC2
names: Similarity
messages: Belongs to the UPF0234 family.

472759:NHAL RS16615
gene id: 472759:NHAL_RS16615
uniprot id: D5C1A0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

472759:NHAL RS18665
gene id: 472759:NHAL_RS18665
uniprot id: D5C3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

472759:NHAL RS07445
gene id: 472759:NHAL_RS07445
uniprot id: D5C1P0
names: Similarity
messages: Belongs to the histone deacetylase family.

472759:NHAL RS02755
gene id: 472759:NHAL_RS02755
uniprot id: D5BW95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

472759:NHAL RS10395
gene id: 472759:NHAL_RS10395
uniprot id: D5C511
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

472759:NHAL RS16980
gene id: 472759:NHAL_RS16980
uniprot id: D5C1H2
names: Similarity
messages: Belongs to the DEAD box helicase family.

472759:NHAL RS11955
gene id: 472759:NHAL_RS11955
uniprot id: D5BVW1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

472759:NHAL RS11645
gene id: 472759:NHAL_RS11645
uniprot id: D5BVP8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

472759:NHAL RS17220
gene id: 472759:NHAL_RS17220
uniprot id: D5C1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

472759:NHAL RS08160
gene id: 472759:NHAL_RS08160
uniprot id: D5C2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

472759:NHAL RS09595
gene id: 472759:NHAL_RS09595
uniprot id: D5C3W1
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

472759:NHAL RS07045
gene id: 472759:NHAL_RS07045
uniprot id: D5C138
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS13030
gene id: 472759:NHAL_RS13030
uniprot id: D5BX79
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

472759:NHAL RS11330
gene id: 472759:NHAL_RS11330
uniprot id: D5BV70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

472759:NHAL RS17055
gene id: 472759:NHAL_RS17055
uniprot id: D5C1I8
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS01675
gene id: 472759:NHAL_RS01675
uniprot id: D5BUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

472759:NHAL RS11065
gene id: 472759:NHAL_RS11065
uniprot id: D5BV14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS04545
gene id: 472759:NHAL_RS04545
uniprot id: D5BYB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

472759:NHAL RS11470
gene id: 472759:NHAL_RS11470
uniprot id: D5BV97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

472759:NHAL RS16800
gene id: 472759:NHAL_RS16800
uniprot id: D5C1D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

472759:NHAL RS02480
gene id: 472759:NHAL_RS02480
uniprot id: D5BW44
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

472759:NHAL RS02590
gene id: 472759:NHAL_RS02590
uniprot id: D5BW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

472759:NHAL RS08465
gene id: 472759:NHAL_RS08465
uniprot id: D5C2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

472759:NHAL RS13830
gene id: 472759:NHAL_RS13830
uniprot id: D5BY07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

472759:NHAL RS16610
gene id: 472759:NHAL_RS16610
uniprot id: D5C199
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

472759:NHAL RS18265
gene id: 472759:NHAL_RS18265
uniprot id: D5C2V6
names: Similarity
messages: Belongs to the thioredoxin family.

472759:NHAL RS15315
gene id: 472759:NHAL_RS15315
uniprot id: D5BZW0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS07820
gene id: 472759:NHAL_RS07820
uniprot id: D5C1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

472759:NHAL RS18495
gene id: 472759:NHAL_RS18495
uniprot id: D5C3C1
names: Similarity
messages: Belongs to the Smg family.

472759:NHAL RS11695
gene id: 472759:NHAL_RS11695
uniprot id: D5BVQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

472759:NHAL RS01595
gene id: 472759:NHAL_RS01595
uniprot id: D5BUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

472759:NHAL RS17325
gene id: 472759:NHAL_RS17325
uniprot id: D5C207
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

472759:NHAL RS17025
gene id: 472759:NHAL_RS17025
uniprot id: D5C1I2
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

472759:NHAL RS11590
gene id: 472759:NHAL_RS11590
uniprot id: D5BVN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

472759:NHAL RS13555
gene id: 472759:NHAL_RS13555
uniprot id: D5BXV1
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

472759:NHAL RS18425
gene id: 472759:NHAL_RS18425
uniprot id: D5C3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS18015
gene id: 472759:NHAL_RS18015
uniprot id: D5C2Q7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS12400
gene id: 472759:NHAL_RS12400
uniprot id: D5BWH5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

472759:NHAL RS13430
gene id: 472759:NHAL_RS13430
uniprot id: D5BXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

472759:NHAL RS09490
gene id: 472759:NHAL_RS09490
uniprot id: D5C3U0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS04210
gene id: 472759:NHAL_RS04210
uniprot id: D5BY48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

472759:NHAL RS18385
gene id: 472759:NHAL_RS18385
uniprot id: D5C399
names: Similarity
messages: Belongs to the GSP E family.

472759:NHAL RS02705
gene id: 472759:NHAL_RS02705
uniprot id: D5BW85
names: Similarity
messages: Belongs to the glutamine synthetase family.

472759:NHAL RS16770
gene id: 472759:NHAL_RS16770
uniprot id: D5C1D0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

472759:NHAL RS10540
gene id: 472759:NHAL_RS10540
uniprot id: D5C540
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

472759:NHAL RS14230
gene id: 472759:NHAL_RS14230
uniprot id: D5BYL0
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS16075
gene id: 472759:NHAL_RS16075
uniprot id: D5C0N1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

472759:NHAL RS11740
gene id: 472759:NHAL_RS11740
uniprot id: D5BVR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

472759:NHAL RS11475
gene id: 472759:NHAL_RS11475
uniprot id: D5BV98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

472759:NHAL RS00380
gene id: 472759:NHAL_RS00380
uniprot id: D5C4A7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

472759:NHAL RS17090
gene id: 472759:NHAL_RS17090
uniprot id: D5C1J6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

472759:NHAL RS02870
gene id: 472759:NHAL_RS02870
uniprot id: D5BWB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

472759:NHAL RS15575
gene id: 472759:NHAL_RS15575
uniprot id: D5C011
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

472759:NHAL RS08285
gene id: 472759:NHAL_RS08285
uniprot id: D5C2H7
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03210
gene id: 472759:NHAL_RS03210
uniprot id: D5BWV4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

472759:NHAL RS03610
gene id: 472759:NHAL_RS03610
uniprot id: D5BXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

472759:NHAL RS15880
gene id: 472759:NHAL_RS15880
uniprot id: D5C0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

472759:NHAL RS04160
gene id: 472759:NHAL_RS04160
uniprot id: D5BXR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

472759:NHAL RS16805
gene id: 472759:NHAL_RS16805
uniprot id: D5C1D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

472759:NHAL RS00320
gene id: 472759:NHAL_RS00320
uniprot id: D5C495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

472759:NHAL RS19740
gene id: 472759:NHAL_RS19740
uniprot id: D5C1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS12085
gene id: 472759:NHAL_RS12085
uniprot id: D5BVY5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

472759:NHAL RS03720
gene id: 472759:NHAL_RS03720
uniprot id: D5BXI1
names: Similarity
messages: Belongs to the RutC family.

472759:NHAL RS17925
gene id: 472759:NHAL_RS17925
uniprot id: D5C2P0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

472759:NHAL RS15175
gene id: 472759:NHAL_RS15175
uniprot id: D5BZG3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

472759:NHAL RS17345
gene id: 472759:NHAL_RS17345
uniprot id: D5C211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS05395
gene id: 472759:NHAL_RS05395
uniprot id: D5BZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

472759:NHAL RS08640
gene id: 472759:NHAL_RS08640
uniprot id: D5C311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

472759:NHAL RS00535
gene id: 472759:NHAL_RS00535
uniprot id: D5C4Q1
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS03555
gene id: 472759:NHAL_RS03555
uniprot id: D5BX25
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

472759:NHAL RS05985
gene id: 472759:NHAL_RS05985
uniprot id: D5BZT1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

472759:NHAL RS16760
gene id: 472759:NHAL_RS16760
uniprot id: D5C1C8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

472759:NHAL RS02600
gene id: 472759:NHAL_RS02600
uniprot id: D5BW64
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS19190
gene id: 472759:NHAL_RS19190
uniprot id: D5C429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

472759:NHAL RS12815
gene id: 472759:NHAL_RS12815
uniprot id: D5BX36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

472759:NHAL RS04625
gene id: 472759:NHAL_RS04625
uniprot id: D5BYC9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

472759:NHAL RS14750
gene id: 472759:NHAL_RS14750
uniprot id: D5BZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

472759:NHAL RS15360
gene id: 472759:NHAL_RS15360
uniprot id: D5BZW9
names: Similarity
messages: Belongs to the PspA/IM30 family.

472759:NHAL RS08720
gene id: 472759:NHAL_RS08720
uniprot id: D5C328
names: Similarity
messages: Belongs to the TonB-dependent receptor family.

472759:NHAL RS11150
gene id: 472759:NHAL_RS11150
uniprot id: D5BV32
names: Similarity
messages: Belongs to the GppA/Ppx family.

472759:NHAL RS10860
gene id: 472759:NHAL_RS10860
uniprot id: D5C5A2
names: Similarity
messages: Belongs to the peptidase S8 family.

472759:NHAL RS00485
gene id: 472759:NHAL_RS00485
uniprot id: D5C4P1
names: Similarity
messages: Belongs to the glutamate synthase family.

472759:NHAL RS12725
gene id: 472759:NHAL_RS12725
uniprot id: D5BWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS11705
gene id: 472759:NHAL_RS11705
uniprot id: D5BVR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

472759:NHAL RS02545
gene id: 472759:NHAL_RS02545
uniprot id: D5BW53
names: Similarity
messages: Belongs to the MoaD family.

472759:NHAL RS16730
gene id: 472759:NHAL_RS16730
uniprot id: D5C1C2
names: Similarity
messages: Belongs to the pyruvate kinase family.

472759:NHAL RS12000
gene id: 472759:NHAL_RS12000
uniprot id: D5BVX0
names: Similarity
messages: Belongs to the skp family.

472759:NHAL RS18210
gene id: 472759:NHAL_RS18210
uniprot id: D5C2U4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

472759:NHAL RS17940
gene id: 472759:NHAL_RS17940
uniprot id: D5C2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

472759:NHAL RS13625
gene id: 472759:NHAL_RS13625
uniprot id: D5BXW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS18390
gene id: 472759:NHAL_RS18390
uniprot id: D5C3A0
names: Similarity
messages: Belongs to the GSP E family.

472759:NHAL RS06310
gene id: 472759:NHAL_RS06310
uniprot id: D5C0B5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

472759:NHAL RS16740
gene id: 472759:NHAL_RS16740
uniprot id: D5C1C4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

472759:NHAL RS08790
gene id: 472759:NHAL_RS08790
uniprot id: D5C343
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS00345
gene id: 472759:NHAL_RS00345
uniprot id: D5C4A0
names: Similarity
messages: Belongs to the SCO1/2 family.

472759:NHAL RS11615
gene id: 472759:NHAL_RS11615
uniprot id: D5BVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

472759:NHAL RS08830
gene id: 472759:NHAL_RS08830
uniprot id: D5C352
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS00590
gene id: 472759:NHAL_RS00590
uniprot id: D5C4R2
names: Subcellular Location Annotation
messages: Cytoplasm

472759:NHAL RS03730
gene id: 472759:NHAL_RS03730
uniprot id: D5BXI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

472759:NHAL RS01600
gene id: 472759:NHAL_RS01600
uniprot id: D5BUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

472759:NHAL RS15015
gene id: 472759:NHAL_RS15015
uniprot id: D5BZD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

472759:NHAL RS00260
gene id: 472759:NHAL_RS00260
uniprot id: D5C484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

472759:NHAL RS12985
gene id: 472759:NHAL_RS12985
uniprot id: D5BX70
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS00180
gene id: 472759:NHAL_RS00180
uniprot id: D5C470
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

472759:NHAL RS02095
gene id: 472759:NHAL_RS02095
uniprot id: D5BVJ2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS01570
gene id: 472759:NHAL_RS01570
uniprot id: D5BUW6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

472759:NHAL RS02565
gene id: 472759:NHAL_RS02565
uniprot id: D5BW57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

472759:NHAL RS05885
gene id: 472759:NHAL_RS05885
uniprot id: D5BZR1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

472759:NHAL RS15115
gene id: 472759:NHAL_RS15115
uniprot id: D5BZF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

472759:NHAL RS11230
gene id: 472759:NHAL_RS11230
uniprot id: D5BV49
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

472759:NHAL RS06085
gene id: 472759:NHAL_RS06085
uniprot id: D5C071
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS18050
gene id: 472759:NHAL_RS18050
uniprot id: D5C2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

472759:NHAL RS05545
gene id: 472759:NHAL_RS05545
uniprot id: D5BZJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

472759:NHAL RS05700
gene id: 472759:NHAL_RS05700
uniprot id: D5BZM3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

472759:NHAL RS14610
gene id: 472759:NHAL_RS14610
uniprot id: D5BYT5
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS05340
gene id: 472759:NHAL_RS05340
uniprot id: D5BZ44
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 8 heme c groups per subunit. One specific heme c group is called heme P460.
messages: Binds 8 heme groups per subunit.
messages: Catalyzes the oxidation of hydroxylamine to nitrite. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is cytochrome c-554.
messages: Homotrimer.
messages: Periplasm

472759:NHAL RS05705
gene id: 472759:NHAL_RS05705
uniprot id: D5BZM4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

472759:NHAL RS04485
gene id: 472759:NHAL_RS04485
uniprot id: D5BYA3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS10100
gene id: 472759:NHAL_RS10100
uniprot id: D5C4J4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

472759:NHAL RS01700
gene id: 472759:NHAL_RS01700
uniprot id: D5BVB5
names: Similarity
messages: Belongs to the BolA/IbaG family.

472759:NHAL RS08635
gene id: 472759:NHAL_RS08635
uniprot id: D5C310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

472759:NHAL RS18145
gene id: 472759:NHAL_RS18145
uniprot id: D5C2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

472759:NHAL RS02140
gene id: 472759:NHAL_RS02140
uniprot id: D5BVJ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

472759:NHAL RS14795
gene id: 472759:NHAL_RS14795
uniprot id: D5BZ92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS11975
gene id: 472759:NHAL_RS11975
uniprot id: D5BVW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

472759:NHAL RS06950
gene id: 472759:NHAL_RS06950
uniprot id: D5C119
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS13255
gene id: 472759:NHAL_RS13255
uniprot id: D5BXC2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS14225
gene id: 472759:NHAL_RS14225
uniprot id: D5BYK9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS19935
gene id: 472759:NHAL_RS19935
uniprot id: D5C182
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

472759:NHAL RS14995
gene id: 472759:NHAL_RS14995
uniprot id: D5BZC9
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS10105
gene id: 472759:NHAL_RS10105
uniprot id: D5C4J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

472759:NHAL RS18770
gene id: 472759:NHAL_RS18770
uniprot id: D5C3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

472759:NHAL RS04540
gene id: 472759:NHAL_RS04540
uniprot id: D5BYB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

472759:NHAL RS18150
gene id: 472759:NHAL_RS18150
uniprot id: D5C2T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

472759:NHAL RS08385
gene id: 472759:NHAL_RS08385
uniprot id: D5C2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

472759:NHAL RS00905
gene id: 472759:NHAL_RS00905
uniprot id: D5C4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

472759:NHAL RS18610
gene id: 472759:NHAL_RS18610
uniprot id: D5C3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

472759:NHAL RS02780
gene id: 472759:NHAL_RS02780
uniprot id: D5BWA0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

472759:NHAL RS02875
gene id: 472759:NHAL_RS02875
uniprot id: D5BWC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

472759:NHAL RS02220
gene id: 472759:NHAL_RS02220
uniprot id: D5BVL3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

472759:NHAL RS08010
gene id: 472759:NHAL_RS08010
uniprot id: D5C2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

472759:NHAL RS01635
gene id: 472759:NHAL_RS01635
uniprot id: D5BUY0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

472759:NHAL RS00110
gene id: 472759:NHAL_RS00110
uniprot id: D5C456
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

472759:NHAL RS01480
gene id: 472759:NHAL_RS01480
uniprot id: D5BUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

472759:NHAL RS03915
gene id: 472759:NHAL_RS03915
uniprot id: D5BXL8
names: Subcellular Location Annotation
messages: Membrane

472759:NHAL RS18900
gene id: 472759:NHAL_RS18900
uniprot id: D5C3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS05295
gene id: 472759:NHAL_RS05295
uniprot id: D5BZ35
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

472759:NHAL RS18915
gene id: 472759:NHAL_RS18915
uniprot id: D5C3K5
names: Similarity
messages: Belongs to the PhoH family.

472759:NHAL RS08895
gene id: 472759:NHAL_RS08895
uniprot id: D5C364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

472759:NHAL RS13060
gene id: 472759:NHAL_RS13060
uniprot id: D5BX85
names: Similarity
messages: Belongs to the HSP15 family.

472759:NHAL RS15905
gene id: 472759:NHAL_RS15905
uniprot id: D5C0J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

472759:NHAL RS03060
gene id: 472759:NHAL_RS03060
uniprot id: D5BWS6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

472759:NHAL RS15455
gene id: 472759:NHAL_RS15455
uniprot id: D5BZY7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

472759:NHAL RS08700
gene id: 472759:NHAL_RS08700
uniprot id: D5C324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

472759:NHAL RS00165
gene id: 472759:NHAL_RS00165
uniprot id: D5C467
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

472759:NHAL RS02365
gene id: 472759:NHAL_RS02365
uniprot id: D5BW21
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS10090
gene id: 472759:NHAL_RS10090
uniprot id: D5C4J2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

472759:NHAL RS08965
gene id: 472759:NHAL_RS08965
uniprot id: D5C360
names: Similarity
messages: Belongs to the universal stress protein A family.

472759:NHAL RS01715
gene id: 472759:NHAL_RS01715
uniprot id: D5BVB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

472759:NHAL RS18660
gene id: 472759:NHAL_RS18660
uniprot id: D5C3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

472759:NHAL RS11855
gene id: 472759:NHAL_RS11855
uniprot id: D5BVU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

472759:NHAL RS19885
gene id: 472759:NHAL_RS19885
uniprot id: D5BXY5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

472759:NHAL RS15970
gene id: 472759:NHAL_RS15970
uniprot id: D5C0L1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

472759:NHAL RS15560
gene id: 472759:NHAL_RS15560
uniprot id: D5C008
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

472759:NHAL RS00020
gene id: 472759:NHAL_RS00020
uniprot id: D5C438
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

472759:NHAL RS07900
gene id: 472759:NHAL_RS07900
uniprot id: D5C2A0
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

472759:NHAL RS16680
gene id: 472759:NHAL_RS16680
uniprot id: D5C1B4
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

472759:NHAL RS17535
gene id: 472759:NHAL_RS17535
uniprot id: D5C250
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

472759:NHAL RS00080
gene id: 472759:NHAL_RS00080
uniprot id: D5C450
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

472759:NHAL RS13105
gene id: 472759:NHAL_RS13105
uniprot id: D5BX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

472759:NHAL RS12010
gene id: 472759:NHAL_RS12010
uniprot id: D5BVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

472759:NHAL RS13645
gene id: 472759:NHAL_RS13645
uniprot id: D5BXW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

472759:NHAL RS09060
gene id: 472759:NHAL_RS09060
uniprot id: D5C3L4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

472759:NHAL RS13570
gene id: 472759:NHAL_RS13570
uniprot id: D5BXV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

472759:NHAL RS12975
gene id: 472759:NHAL_RS12975
uniprot id: D5BX68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

472759:NHAL RS06625
gene id: 472759:NHAL_RS06625
uniprot id: D5C0I2
names: Similarity
messages: Belongs to the HupF/HypC family.

472759:NHAL RS11415
gene id: 472759:NHAL_RS11415
uniprot id: D5BV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

472759:NHAL RS17250
gene id: 472759:NHAL_RS17250
uniprot id: D5C1Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

472759:NHAL RS06385
gene id: 472759:NHAL_RS06385
uniprot id: D5C0D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

472759:NHAL RS11965
gene id: 472759:NHAL_RS11965
uniprot id: D5BVW3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

472759:NHAL RS18085
gene id: 472759:NHAL_RS18085
uniprot id: D5C2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

472759:NHAL RS02885
gene id: 472759:NHAL_RS02885
uniprot id: D5BWC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

472759:NHAL RS04580
gene id: 472759:NHAL_RS04580
uniprot id: D5BYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.