471857:SVIR RS05285
gene id: 471857:SVIR_RS05285
uniprot id: C7MZ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

471857:SVIR RS02950
gene id: 471857:SVIR_RS02950
uniprot id: C7MUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

471857:SVIR RS18630
gene id: 471857:SVIR_RS18630
uniprot id: C7MRG0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS05115
gene id: 471857:SVIR_RS05115
uniprot id: C7MYY4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

471857:SVIR RS01970
gene id: 471857:SVIR_RS01970
uniprot id: C7MTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

471857:SVIR RS02080
gene id: 471857:SVIR_RS02080
uniprot id: C7MTX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

471857:SVIR RS18790
gene id: 471857:SVIR_RS18790
uniprot id: C7MRJ2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

471857:SVIR RS00010
gene id: 471857:SVIR_RS00010
uniprot id: C7MRN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

471857:SVIR RS02055
gene id: 471857:SVIR_RS02055
uniprot id: C7MTW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

471857:SVIR RS08250
gene id: 471857:SVIR_RS08250
uniprot id: C7MT88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

471857:SVIR RS15595
gene id: 471857:SVIR_RS15595
uniprot id: C7MYS4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS19095
gene id: 471857:SVIR_RS19095
uniprot id: C7MRY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS16490
gene id: 471857:SVIR_RS16490
uniprot id: C7N0D1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471857:SVIR RS01955
gene id: 471857:SVIR_RS01955
uniprot id: C7MTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

471857:SVIR RS16860
gene id: 471857:SVIR_RS16860
uniprot id: C7MPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471857:SVIR RS09300
gene id: 471857:SVIR_RS09300
uniprot id: C7MUF1
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS10855
gene id: 471857:SVIR_RS10855
uniprot id: C7MWY1
names: Similarity
messages: Belongs to the peptidase S8 family.

471857:SVIR RS13345
gene id: 471857:SVIR_RS13345
uniprot id: C7MV86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

471857:SVIR RS06155
gene id: 471857:SVIR_RS06155
uniprot id: C7MPR5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

471857:SVIR RS01745
gene id: 471857:SVIR_RS01745
uniprot id: C7MTG2
names: Similarity
messages: Belongs to the peptidase S1 family.

471857:SVIR RS15350
gene id: 471857:SVIR_RS15350
uniprot id: C7MYM4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

471857:SVIR RS02045
gene id: 471857:SVIR_RS02045
uniprot id: C7MTW4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

471857:SVIR RS06990
gene id: 471857:SVIR_RS06990
uniprot id: C7MQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

471857:SVIR RS03490
gene id: 471857:SVIR_RS03490
uniprot id: C7MVR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS19240
gene id: 471857:SVIR_RS19240
uniprot id: C7MS11
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

471857:SVIR RS16805
gene id: 471857:SVIR_RS16805
uniprot id: C7N0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS00770
gene id: 471857:SVIR_RS00770
uniprot id: C7MSD1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471857:SVIR RS14415
gene id: 471857:SVIR_RS14415
uniprot id: C7MX12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS08235
gene id: 471857:SVIR_RS08235
uniprot id: C7MT86
names: Similarity
messages: Belongs to the UPF0098 family.

471857:SVIR RS01790
gene id: 471857:SVIR_RS01790
uniprot id: C7MTH0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

471857:SVIR RS02160
gene id: 471857:SVIR_RS02160
uniprot id: C7MTY8
names: Similarity
messages: Belongs to the WXG100 family.

471857:SVIR RS17500
gene id: 471857:SVIR_RS17500
uniprot id: C7MQK2
names: Similarity
messages: Belongs to the peptidase S13 family.

471857:SVIR RS14315
gene id: 471857:SVIR_RS14315
uniprot id: C7MWZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471857:SVIR RS18995
gene id: 471857:SVIR_RS18995
uniprot id: C7MRN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS04875
gene id: 471857:SVIR_RS04875
uniprot id: C7MYA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

471857:SVIR RS03770
gene id: 471857:SVIR_RS03770
uniprot id: C7MWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

471857:SVIR RS04820
gene id: 471857:SVIR_RS04820
uniprot id: C7MY98
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

471857:SVIR RS19455
gene id: 471857:SVIR_RS19455
uniprot id: C7MS53
names: Similarity
messages: Belongs to the thioredoxin family.

471857:SVIR RS08605
gene id: 471857:SVIR_RS08605
uniprot id: C7MTR1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

471857:SVIR RS01050
gene id: 471857:SVIR_RS01050
uniprot id: C7MST4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

471857:SVIR RS12720
gene id: 471857:SVIR_RS12720
uniprot id: C7N058
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS15795
gene id: 471857:SVIR_RS15795
uniprot id: C7MZH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

471857:SVIR RS17220
gene id: 471857:SVIR_RS17220
uniprot id: C7MQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

471857:SVIR RS04510
gene id: 471857:SVIR_RS04510
uniprot id: C7MY36
names: Similarity
messages: Belongs to the arginase family.

471857:SVIR RS17540
gene id: 471857:SVIR_RS17540
uniprot id: C7MQK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

471857:SVIR RS05470
gene id: 471857:SVIR_RS05470
uniprot id: C7MZ57
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS12485
gene id: 471857:SVIR_RS12485
uniprot id: C7N014
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS06285
gene id: 471857:SVIR_RS06285
uniprot id: C7MPU0
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07590
gene id: 471857:SVIR_RS07590
uniprot id: C7MSJ6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS11495
gene id: 471857:SVIR_RS11495
uniprot id: C7MYE2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

471857:SVIR RS18620
gene id: 471857:SVIR_RS18620
uniprot id: C7MRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

471857:SVIR RS07085
gene id: 471857:SVIR_RS07085
uniprot id: C7MQV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

471857:SVIR RS18780
gene id: 471857:SVIR_RS18780
uniprot id: C7MRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS17410
gene id: 471857:SVIR_RS17410
uniprot id: C7MQI4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

471857:SVIR RS06680
gene id: 471857:SVIR_RS06680
uniprot id: C7MQB5
names: Similarity
messages: Belongs to the Fur family.

471857:SVIR RS11080
gene id: 471857:SVIR_RS11080
uniprot id: C7MXK1
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS04955
gene id: 471857:SVIR_RS04955
uniprot id: C7MYC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS05165
gene id: 471857:SVIR_RS05165
uniprot id: C7MYZ4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

471857:SVIR RS10110
gene id: 471857:SVIR_RS10110
uniprot id: C7MVZ0
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS05205
gene id: 471857:SVIR_RS05205
uniprot id: C7MZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS16705
gene id: 471857:SVIR_RS16705
uniprot id: C7N0H3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

471857:SVIR RS12085
gene id: 471857:SVIR_RS12085
uniprot id: C7MZA5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS06020
gene id: 471857:SVIR_RS06020
uniprot id: C7MPN9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS06850
gene id: 471857:SVIR_RS06850
uniprot id: C7MQF0
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

471857:SVIR RS06535
gene id: 471857:SVIR_RS06535
uniprot id: C7MQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS20135
gene id: 471857:SVIR_RS20135
uniprot id: C7MSR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

471857:SVIR RS06100
gene id: 471857:SVIR_RS06100
uniprot id: C7MPQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

471857:SVIR RS04195
gene id: 471857:SVIR_RS04195
uniprot id: C7MXB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS17175
gene id: 471857:SVIR_RS17175
uniprot id: C7MQ45
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

471857:SVIR RS08645
gene id: 471857:SVIR_RS08645
uniprot id: C7MTR9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

471857:SVIR RS01950
gene id: 471857:SVIR_RS01950
uniprot id: C7MTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

471857:SVIR RS11215
gene id: 471857:SVIR_RS11215
uniprot id: C7MXM8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS18300
gene id: 471857:SVIR_RS18300
uniprot id: C7MR94
names: Cofactor
messages: Binds 1 zinc ion per subunit.

471857:SVIR RS07405
gene id: 471857:SVIR_RS07405
uniprot id: C7MR11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS10360
gene id: 471857:SVIR_RS10360
uniprot id: C7MWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471857:SVIR RS12475
gene id: 471857:SVIR_RS12475
uniprot id: C7N012
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS06610
gene id: 471857:SVIR_RS06610
uniprot id: C7MQA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

471857:SVIR RS13355
gene id: 471857:SVIR_RS13355
uniprot id: C7MV88
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

471857:SVIR RS18725
gene id: 471857:SVIR_RS18725
uniprot id: C7MRH9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

471857:SVIR RS09740
gene id: 471857:SVIR_RS09740
uniprot id: C7MV65
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

471857:SVIR RS07640
gene id: 471857:SVIR_RS07640
uniprot id: C7MSK6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

471857:SVIR RS08035
gene id: 471857:SVIR_RS08035
uniprot id: C7MT46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS04980
gene id: 471857:SVIR_RS04980
uniprot id: C7MYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

471857:SVIR RS17195
gene id: 471857:SVIR_RS17195
uniprot id: C7MQ49
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS18140
gene id: 471857:SVIR_RS18140
uniprot id: C7MR67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471857:SVIR RS13470
gene id: 471857:SVIR_RS13470
uniprot id: C7MVB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

471857:SVIR RS09365
gene id: 471857:SVIR_RS09365
uniprot id: C7MUZ0
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

471857:SVIR RS03505
gene id: 471857:SVIR_RS03505
uniprot id: C7MVR7
names: Similarity
messages: Belongs to the UxaA family.

471857:SVIR RS04020
gene id: 471857:SVIR_RS04020
uniprot id: C7MWM7
names: Similarity
messages: Belongs to the universal stress protein A family.

471857:SVIR RS05110
gene id: 471857:SVIR_RS05110
uniprot id: C7MYY3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

471857:SVIR RS01690
gene id: 471857:SVIR_RS01690
uniprot id: C7MTF4
names: Similarity
messages: Belongs to the UPF0234 family.

471857:SVIR RS10575
gene id: 471857:SVIR_RS10575
uniprot id: C7MWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS17205
gene id: 471857:SVIR_RS17205
uniprot id: C7MQ51
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS15060
gene id: 471857:SVIR_RS15060
uniprot id: C7MXX9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

471857:SVIR RS18640
gene id: 471857:SVIR_RS18640
uniprot id: C7MRG2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

471857:SVIR RS19310
gene id: 471857:SVIR_RS19310
uniprot id: C7MS25
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

471857:SVIR RS15720
gene id: 471857:SVIR_RS15720
uniprot id: C7MYU9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07900
gene id: 471857:SVIR_RS07900
uniprot id: C7MSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS13390
gene id: 471857:SVIR_RS13390
uniprot id: C7MV95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

471857:SVIR RS06050
gene id: 471857:SVIR_RS06050
uniprot id: C7MPP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

471857:SVIR RS03985
gene id: 471857:SVIR_RS03985
uniprot id: C7MWM0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

471857:SVIR RS17815
gene id: 471857:SVIR_RS17815
uniprot id: C7MQR4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

471857:SVIR RS05975
gene id: 471857:SVIR_RS05975
uniprot id: C7MPM9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07075
gene id: 471857:SVIR_RS07075
uniprot id: C7MQU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

471857:SVIR RS18900
gene id: 471857:SVIR_RS18900
uniprot id: C7MRL4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

471857:SVIR RS14825
gene id: 471857:SVIR_RS14825
uniprot id: C7MXT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS01080
gene id: 471857:SVIR_RS01080
uniprot id: C7MSU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS05795
gene id: 471857:SVIR_RS05795
uniprot id: C7MZX3
names: Similarity
messages: Belongs to the peptidase M1 family.

471857:SVIR RS19055
gene id: 471857:SVIR_RS19055
uniprot id: C7MRX4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

471857:SVIR RS06250
gene id: 471857:SVIR_RS06250
uniprot id: C7MPT3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

471857:SVIR RS17585
gene id: 471857:SVIR_RS17585
uniprot id: C7MQL9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS08600
gene id: 471857:SVIR_RS08600
uniprot id: C7MTR0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

471857:SVIR RS14455
gene id: 471857:SVIR_RS14455
uniprot id: C7MX20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

471857:SVIR RS07855
gene id: 471857:SVIR_RS07855
uniprot id: C7MSQ0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

471857:SVIR RS15150
gene id: 471857:SVIR_RS15150
uniprot id: C7MXZ7
names: Similarity
messages: Belongs to the PGI/PMI family.

471857:SVIR RS10375
gene id: 471857:SVIR_RS10375
uniprot id: C7MWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

471857:SVIR RS00615
gene id: 471857:SVIR_RS00615
uniprot id: C7MSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

471857:SVIR RS04885
gene id: 471857:SVIR_RS04885
uniprot id: C7MYB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

471857:SVIR RS13535
gene id: 471857:SVIR_RS13535
uniprot id: C7MVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS07275
gene id: 471857:SVIR_RS07275
uniprot id: C7MQY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471857:SVIR RS05045
gene id: 471857:SVIR_RS05045
uniprot id: C7MYX0
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04170
gene id: 471857:SVIR_RS04170
uniprot id: C7MXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

471857:SVIR RS00855
gene id: 471857:SVIR_RS00855
uniprot id: C7MSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

471857:SVIR RS07665
gene id: 471857:SVIR_RS07665
uniprot id: C7MSL1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

471857:SVIR RS01440
gene id: 471857:SVIR_RS01440
uniprot id: C7MT13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS14395
gene id: 471857:SVIR_RS14395
uniprot id: C7MX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS13360
gene id: 471857:SVIR_RS13360
uniprot id: C7MV89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

471857:SVIR RS06860
gene id: 471857:SVIR_RS06860
uniprot id: C7MQF2
names: Similarity
messages: Belongs to the peptidase S45 family.

471857:SVIR RS14400
gene id: 471857:SVIR_RS14400
uniprot id: C7MX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS05935
gene id: 471857:SVIR_RS05935
uniprot id: C7MZZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

471857:SVIR RS06115
gene id: 471857:SVIR_RS06115
uniprot id: C7MPQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

471857:SVIR RS02980
gene id: 471857:SVIR_RS02980
uniprot id: C7MUW6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

471857:SVIR RS00310
gene id: 471857:SVIR_RS00310
uniprot id: C7MRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS01750
gene id: 471857:SVIR_RS01750
uniprot id: C7MTG3
names: Similarity
messages: Belongs to the UPF0336 family.

471857:SVIR RS00740
gene id: 471857:SVIR_RS00740
uniprot id: C7MSC5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

471857:SVIR RS07630
gene id: 471857:SVIR_RS07630
uniprot id: C7MSK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS17030
gene id: 471857:SVIR_RS17030
uniprot id: C7MQ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

471857:SVIR RS11385
gene id: 471857:SVIR_RS11385
uniprot id: C7MXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

471857:SVIR RS06545
gene id: 471857:SVIR_RS06545
uniprot id: C7MQ88
names: Subcellular Location Annotation
messages: Cytoplasm

471857:SVIR RS10610
gene id: 471857:SVIR_RS10610
uniprot id: C7MWT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS07530
gene id: 471857:SVIR_RS07530
uniprot id: C7MSI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

471857:SVIR RS14635
gene id: 471857:SVIR_RS14635
uniprot id: C7MX56
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

471857:SVIR RS00515
gene id: 471857:SVIR_RS00515
uniprot id: C7MS80
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471857:SVIR RS13585
gene id: 471857:SVIR_RS13585
uniprot id: C7MVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

471857:SVIR RS06580
gene id: 471857:SVIR_RS06580
uniprot id: C7MQ95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS11420
gene id: 471857:SVIR_RS11420
uniprot id: C7MXR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS07340
gene id: 471857:SVIR_RS07340
uniprot id: C7MQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

471857:SVIR RS17405
gene id: 471857:SVIR_RS17405
uniprot id: C7MQI3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

471857:SVIR RS14590
gene id: 471857:SVIR_RS14590
uniprot id: C7MX47
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471857:SVIR RS16620
gene id: 471857:SVIR_RS16620
uniprot id: C7N0F6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

471857:SVIR RS01095
gene id: 471857:SVIR_RS01095
uniprot id: C7MSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

471857:SVIR RS15495
gene id: 471857:SVIR_RS15495
uniprot id: C7MYQ3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

471857:SVIR RS00660
gene id: 471857:SVIR_RS00660
uniprot id: C7MSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS18810
gene id: 471857:SVIR_RS18810
uniprot id: C7MRJ6
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

471857:SVIR RS04300
gene id: 471857:SVIR_RS04300
uniprot id: C7MXD5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS05000
gene id: 471857:SVIR_RS05000
uniprot id: C7MYW2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

471857:SVIR RS02875
gene id: 471857:SVIR_RS02875
uniprot id: C7MUU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

471857:SVIR RS07595
gene id: 471857:SVIR_RS07595
uniprot id: C7MSJ7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

471857:SVIR RS02585
gene id: 471857:SVIR_RS02585
uniprot id: C7MUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

471857:SVIR RS07485
gene id: 471857:SVIR_RS07485
uniprot id: C7MSH5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS17460
gene id: 471857:SVIR_RS17460
uniprot id: C7MQJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

471857:SVIR RS06225
gene id: 471857:SVIR_RS06225
uniprot id: C7MPS8
names: Similarity
messages: Belongs to the barstar family.

471857:SVIR RS13170
gene id: 471857:SVIR_RS13170
uniprot id: C7MUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

471857:SVIR RS01345
gene id: 471857:SVIR_RS01345
uniprot id: C7MSZ4
names: Cofactor
messages: Binds 1 FAD per subunit.

471857:SVIR RS04370
gene id: 471857:SVIR_RS04370
uniprot id: C7MXE9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

471857:SVIR RS08010
gene id: 471857:SVIR_RS08010
uniprot id: C7MT41
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS02245
gene id: 471857:SVIR_RS02245
uniprot id: C7MU04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS08825
gene id: 471857:SVIR_RS08825
uniprot id: C7MTV2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

471857:SVIR RS03070
gene id: 471857:SVIR_RS03070
uniprot id: C7MVH8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS16390
gene id: 471857:SVIR_RS16390
uniprot id: C7N0B1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS02065
gene id: 471857:SVIR_RS02065
uniprot id: C7MTW8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471857:SVIR RS14265
gene id: 471857:SVIR_RS14265
uniprot id: C7MWD0
names: Similarity
messages: Belongs to the peptidase S58 family.

471857:SVIR RS10840
gene id: 471857:SVIR_RS10840
uniprot id: C7MWX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

471857:SVIR RS07295
gene id: 471857:SVIR_RS07295
uniprot id: C7MQY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

471857:SVIR RS00355
gene id: 471857:SVIR_RS00355
uniprot id: C7MRU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS10745
gene id: 471857:SVIR_RS10745
uniprot id: C7MWV8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

471857:SVIR RS10285
gene id: 471857:SVIR_RS10285
uniprot id: C7MW25
names: Similarity
messages: Belongs to the Fur family.

471857:SVIR RS07780
gene id: 471857:SVIR_RS07780
uniprot id: C7MSN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

471857:SVIR RS02745
gene id: 471857:SVIR_RS02745
uniprot id: C7MUR8
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

471857:SVIR RS11020
gene id: 471857:SVIR_RS11020
uniprot id: C7MXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

471857:SVIR RS13200
gene id: 471857:SVIR_RS13200
uniprot id: C7MUL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

471857:SVIR RS17275
gene id: 471857:SVIR_RS17275
uniprot id: C7MQ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS01815
gene id: 471857:SVIR_RS01815
uniprot id: C7MTH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

471857:SVIR RS16960
gene id: 471857:SVIR_RS16960
uniprot id: C7MQ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

471857:SVIR RS10750
gene id: 471857:SVIR_RS10750
uniprot id: C7MWV9
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

471857:SVIR RS12550
gene id: 471857:SVIR_RS12550
uniprot id: C7N027
names: Subcellular Location Annotation
messages: Cytoplasm

471857:SVIR RS16855
gene id: 471857:SVIR_RS16855
uniprot id: C7MPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471857:SVIR RS06260
gene id: 471857:SVIR_RS06260
uniprot id: C7MPT5
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

471857:SVIR RS14445
gene id: 471857:SVIR_RS14445
uniprot id: C7MX18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

471857:SVIR RS09940
gene id: 471857:SVIR_RS09940
uniprot id: C7MVV7
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

471857:SVIR RS18910
gene id: 471857:SVIR_RS18910
uniprot id: C7MRL6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

471857:SVIR RS19320
gene id: 471857:SVIR_RS19320
uniprot id: C7MS27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

471857:SVIR RS05965
gene id: 471857:SVIR_RS05965
uniprot id: C7MPM7
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

471857:SVIR RS02620
gene id: 471857:SVIR_RS02620
uniprot id: C7MUP6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

471857:SVIR RS04505
gene id: 471857:SVIR_RS04505
uniprot id: C7MY35
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

471857:SVIR RS16345
gene id: 471857:SVIR_RS16345
uniprot id: C7N0A2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

471857:SVIR RS17485
gene id: 471857:SVIR_RS17485
uniprot id: C7MQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

471857:SVIR RS08290
gene id: 471857:SVIR_RS08290
uniprot id: C7MT96
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

471857:SVIR RS19790
gene id: 471857:SVIR_RS19790
uniprot id: C7MWG2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

471857:SVIR RS01565
gene id: 471857:SVIR_RS01565
uniprot id: C7MTC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS08705
gene id: 471857:SVIR_RS08705
uniprot id: C7MTT0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS10355
gene id: 471857:SVIR_RS10355
uniprot id: C7MWN5
names: Similarity
messages: Belongs to the Fur family.

471857:SVIR RS03760
gene id: 471857:SVIR_RS03760
uniprot id: C7MWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

471857:SVIR RS07700
gene id: 471857:SVIR_RS07700
uniprot id: C7MSL8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

471857:SVIR RS01525
gene id: 471857:SVIR_RS01525
uniprot id: C7MTC1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS15260
gene id: 471857:SVIR_RS15260
uniprot id: C7MY19
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

471857:SVIR RS11180
gene id: 471857:SVIR_RS11180
uniprot id: C7MXM1
names: Similarity
messages: Belongs to the universal stress protein A family.

471857:SVIR RS18110
gene id: 471857:SVIR_RS18110
uniprot id: C7MR61
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS13420
gene id: 471857:SVIR_RS13420
uniprot id: C7MVA1
names: Similarity
messages: Belongs to the histone deacetylase family.

471857:SVIR RS08885
gene id: 471857:SVIR_RS08885
uniprot id: C7MU68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS04190
gene id: 471857:SVIR_RS04190
uniprot id: C7MXB3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

471857:SVIR RS09610
gene id: 471857:SVIR_RS09610
uniprot id: C7MV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

471857:SVIR RS14645
gene id: 471857:SVIR_RS14645
uniprot id: C7MX58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

471857:SVIR RS12780
gene id: 471857:SVIR_RS12780
uniprot id: C7N070
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471857:SVIR RS14440
gene id: 471857:SVIR_RS14440
uniprot id: C7MX17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

471857:SVIR RS06000
gene id: 471857:SVIR_RS06000
uniprot id: C7MPN5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07550
gene id: 471857:SVIR_RS07550
uniprot id: C7MSI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

471857:SVIR RS05980
gene id: 471857:SVIR_RS05980
uniprot id: C7MPN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

471857:SVIR RS06965
gene id: 471857:SVIR_RS06965
uniprot id: C7MQS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

471857:SVIR RS02285
gene id: 471857:SVIR_RS02285
uniprot id: C7MU12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

471857:SVIR RS09120
gene id: 471857:SVIR_RS09120
uniprot id: C7MUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS01040
gene id: 471857:SVIR_RS01040
uniprot id: C7MST2
names: Similarity
messages: Belongs to the asparagine synthetase family.

471857:SVIR RS10930
gene id: 471857:SVIR_RS10930
uniprot id: C7MXH1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

471857:SVIR RS14705
gene id: 471857:SVIR_RS14705
uniprot id: C7MX69
names: Similarity
messages: Belongs to the TPP enzyme family.

471857:SVIR RS16415
gene id: 471857:SVIR_RS16415
uniprot id: C7N0B6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

471857:SVIR RS09750
gene id: 471857:SVIR_RS09750
uniprot id: C7MV67
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

471857:SVIR RS04415
gene id: 471857:SVIR_RS04415
uniprot id: C7MXF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

471857:SVIR RS19295
gene id: 471857:SVIR_RS19295
uniprot id: C7MS22
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

471857:SVIR RS11450
gene id: 471857:SVIR_RS11450
uniprot id: C7MYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

471857:SVIR RS17795
gene id: 471857:SVIR_RS17795
uniprot id: C7MQR0
names: Similarity
messages: Belongs to the Fur family.

471857:SVIR RS09190
gene id: 471857:SVIR_RS09190
uniprot id: C7MUC8
names: Similarity
messages: Belongs to the GcvT family.

471857:SVIR RS06325
gene id: 471857:SVIR_RS06325
uniprot id: C7MPU8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

471857:SVIR RS01810
gene id: 471857:SVIR_RS01810
uniprot id: C7MTH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

471857:SVIR RS02695
gene id: 471857:SVIR_RS02695
uniprot id: C7MUR1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS02105
gene id: 471857:SVIR_RS02105
uniprot id: C7MTX5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

471857:SVIR RS05940
gene id: 471857:SVIR_RS05940
uniprot id: C7MPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

471857:SVIR RS08160
gene id: 471857:SVIR_RS08160
uniprot id: C7MT71
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS18430
gene id: 471857:SVIR_RS18430
uniprot id: C7MRC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

471857:SVIR RS14230
gene id: 471857:SVIR_RS14230
uniprot id: C7MWC3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

471857:SVIR RS05655
gene id: 471857:SVIR_RS05655
uniprot id: C7MZU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

471857:SVIR RS19000
gene id: 471857:SVIR_RS19000
uniprot id: C7MRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

471857:SVIR RS03465
gene id: 471857:SVIR_RS03465
uniprot id: C7MVR0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

471857:SVIR RS01290
gene id: 471857:SVIR_RS01290
uniprot id: C7MSY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

471857:SVIR RS14120
gene id: 471857:SVIR_RS14120
uniprot id: C7MWA2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

471857:SVIR RS00590
gene id: 471857:SVIR_RS00590
uniprot id: C7MS95
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07415
gene id: 471857:SVIR_RS07415
uniprot id: C7MR13
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

471857:SVIR RS02085
gene id: 471857:SVIR_RS02085
uniprot id: C7MTX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

471857:SVIR RS07555
gene id: 471857:SVIR_RS07555
uniprot id: C7MSI9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

471857:SVIR RS02145
gene id: 471857:SVIR_RS02145
uniprot id: C7MTY5
names: Similarity
messages: Belongs to the EccD/Snm4 family.

471857:SVIR RS13735
gene id: 471857:SVIR_RS13735
uniprot id: C7MVG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

471857:SVIR RS10210
gene id: 471857:SVIR_RS10210
uniprot id: C7MW10
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Homotetramer.
messages: Inhibited by cyanuric acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer and the active site possess nearly threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads, but one of the 3 active site surfaces varies in composition suggesting it is involved in confering substrate specificity.

471857:SVIR RS12490
gene id: 471857:SVIR_RS12490
uniprot id: C7N015
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

471857:SVIR RS13895
gene id: 471857:SVIR_RS13895
uniprot id: C7MW58
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS09155
gene id: 471857:SVIR_RS09155
uniprot id: C7MUC1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

471857:SVIR RS06950
gene id: 471857:SVIR_RS06950
uniprot id: C7MQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471857:SVIR RS06550
gene id: 471857:SVIR_RS06550
uniprot id: C7MQ89
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

471857:SVIR RS14450
gene id: 471857:SVIR_RS14450
uniprot id: C7MX19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

471857:SVIR RS18905
gene id: 471857:SVIR_RS18905
uniprot id: C7MRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

471857:SVIR RS08865
gene id: 471857:SVIR_RS08865
uniprot id: C7MU64
names: Similarity
messages: Belongs to the peptidase S8 family.

471857:SVIR RS15250
gene id: 471857:SVIR_RS15250
uniprot id: C7MY17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS06205
gene id: 471857:SVIR_RS06205
uniprot id: C7MPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

471857:SVIR RS15440
gene id: 471857:SVIR_RS15440
uniprot id: C7MYP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS13700
gene id: 471857:SVIR_RS13700
uniprot id: C7MVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471857:SVIR RS19030
gene id: 471857:SVIR_RS19030
uniprot id: C7MRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS12315
gene id: 471857:SVIR_RS12315
uniprot id: C7MZF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

471857:SVIR RS18610
gene id: 471857:SVIR_RS18610
uniprot id: C7MRF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

471857:SVIR RS02590
gene id: 471857:SVIR_RS02590
uniprot id: C7MUP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

471857:SVIR RS01710
gene id: 471857:SVIR_RS01710
uniprot id: C7MTF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

471857:SVIR RS16350
gene id: 471857:SVIR_RS16350
uniprot id: C7N0A3
names: Similarity
messages: Belongs to the clavaminate synthase family.

471857:SVIR RS11165
gene id: 471857:SVIR_RS11165
uniprot id: C7MXL8
names: Similarity
messages: Belongs to the universal stress protein A family.

471857:SVIR RS09720
gene id: 471857:SVIR_RS09720
uniprot id: C7MV61
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

471857:SVIR RS10980
gene id: 471857:SVIR_RS10980
uniprot id: C7MXI1
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS01555
gene id: 471857:SVIR_RS01555
uniprot id: C7MTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

471857:SVIR RS07545
gene id: 471857:SVIR_RS07545
uniprot id: C7MSI7
names: Similarity
messages: Belongs to the peptidase M24B family.

471857:SVIR RS06105
gene id: 471857:SVIR_RS06105
uniprot id: C7MPQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

471857:SVIR RS02180
gene id: 471857:SVIR_RS02180
uniprot id: C7MTZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

471857:SVIR RS00480
gene id: 471857:SVIR_RS00480
uniprot id: C7MS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

471857:SVIR RS06330
gene id: 471857:SVIR_RS06330
uniprot id: C7MPU9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471857:SVIR RS12190
gene id: 471857:SVIR_RS12190
uniprot id: C7MZC6
names: Similarity
messages: Belongs to the EspG family.

471857:SVIR RS03805
gene id: 471857:SVIR_RS03805
uniprot id: C7MWI4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

471857:SVIR RS05210
gene id: 471857:SVIR_RS05210
uniprot id: C7MZ03
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

471857:SVIR RS17505
gene id: 471857:SVIR_RS17505
uniprot id: C7MQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

471857:SVIR RS10330
gene id: 471857:SVIR_RS10330
uniprot id: C7MW34
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

471857:SVIR RS18200
gene id: 471857:SVIR_RS18200
uniprot id: C7MR76
names: Subcellular Location Annotation
messages: Cytoplasm

471857:SVIR RS02190
gene id: 471857:SVIR_RS02190
uniprot id: C7MTZ4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

471857:SVIR RS12565
gene id: 471857:SVIR_RS12565
uniprot id: C7N030
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

471857:SVIR RS02155
gene id: 471857:SVIR_RS02155
uniprot id: C7MTY7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

471857:SVIR RS07305
gene id: 471857:SVIR_RS07305
uniprot id: C7MQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

471857:SVIR RS10740
gene id: 471857:SVIR_RS10740
uniprot id: C7MWV7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

471857:SVIR RS04770
gene id: 471857:SVIR_RS04770
uniprot id: C7MY88
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

471857:SVIR RS05295
gene id: 471857:SVIR_RS05295
uniprot id: C7MZ20
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

471857:SVIR RS07830
gene id: 471857:SVIR_RS07830
uniprot id: C7MSP5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07155
gene id: 471857:SVIR_RS07155
uniprot id: C7MQW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

471857:SVIR RS17775
gene id: 471857:SVIR_RS17775
uniprot id: C7MQQ6
names: Similarity
messages: Belongs to the Dps family.

471857:SVIR RS07615
gene id: 471857:SVIR_RS07615
uniprot id: C7MSK1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS09565
gene id: 471857:SVIR_RS09565
uniprot id: C7MV30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

471857:SVIR RS15410
gene id: 471857:SVIR_RS15410
uniprot id: C7MYN6
names: Similarity
messages: Belongs to the FBPase class 2 family.

471857:SVIR RS05560
gene id: 471857:SVIR_RS05560
uniprot id: C7MZS8
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

471857:SVIR RS10935
gene id: 471857:SVIR_RS10935
uniprot id: C7MXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS05100
gene id: 471857:SVIR_RS05100
uniprot id: C7MYY1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS09870
gene id: 471857:SVIR_RS09870
uniprot id: C7MVU3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS18425
gene id: 471857:SVIR_RS18425
uniprot id: C7MRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

471857:SVIR RS04660
gene id: 471857:SVIR_RS04660
uniprot id: C7MY66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

471857:SVIR RS05305
gene id: 471857:SVIR_RS05305
uniprot id: C7MZ22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

471857:SVIR RS10765
gene id: 471857:SVIR_RS10765
uniprot id: C7MWW2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

471857:SVIR RS11425
gene id: 471857:SVIR_RS11425
uniprot id: C7MXR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS11920
gene id: 471857:SVIR_RS11920
uniprot id: C7MZ70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

471857:SVIR RS11890
gene id: 471857:SVIR_RS11890
uniprot id: C7MZ64
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS19525
gene id: 471857:SVIR_RS19525
uniprot id: C7MRV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS16460
gene id: 471857:SVIR_RS16460
uniprot id: C7N0C5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS01495
gene id: 471857:SVIR_RS01495
uniprot id: C7MTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

471857:SVIR RS18000
gene id: 471857:SVIR_RS18000
uniprot id: C7MR40
names: Similarity
messages: Belongs to the CsoR family.

471857:SVIR RS11360
gene id: 471857:SVIR_RS11360
uniprot id: C7MXQ7
names: Similarity
messages: Belongs to the CdaR family.

471857:SVIR RS05770
gene id: 471857:SVIR_RS05770
uniprot id: C7MZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

471857:SVIR RS13605
gene id: 471857:SVIR_RS13605
uniprot id: C7MVD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

471857:SVIR RS00850
gene id: 471857:SVIR_RS00850
uniprot id: C7MSE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

471857:SVIR RS13640
gene id: 471857:SVIR_RS13640
uniprot id: C7MVE5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

471857:SVIR RS04145
gene id: 471857:SVIR_RS04145
uniprot id: C7MXA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

471857:SVIR RS07315
gene id: 471857:SVIR_RS07315
uniprot id: C7MQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

471857:SVIR RS02675
gene id: 471857:SVIR_RS02675
uniprot id: C7MUQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS18540
gene id: 471857:SVIR_RS18540
uniprot id: C7MRE2
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04710
gene id: 471857:SVIR_RS04710
uniprot id: C7MY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

471857:SVIR RS16445
gene id: 471857:SVIR_RS16445
uniprot id: C7N0C2
names: Similarity
messages: Belongs to the citrate synthase family.

471857:SVIR RS03250
gene id: 471857:SVIR_RS03250
uniprot id: C7MVL7
names: Similarity
messages: Belongs to the DEAD box helicase family.

471857:SVIR RS12515
gene id: 471857:SVIR_RS12515
uniprot id: C7N020
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

471857:SVIR RS04870
gene id: 471857:SVIR_RS04870
uniprot id: C7MYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

471857:SVIR RS05010
gene id: 471857:SVIR_RS05010
uniprot id: C7MYW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

471857:SVIR RS17605
gene id: 471857:SVIR_RS17605
uniprot id: C7MQM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

471857:SVIR RS17040
gene id: 471857:SVIR_RS17040
uniprot id: C7MQ19
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

471857:SVIR RS05690
gene id: 471857:SVIR_RS05690
uniprot id: C7MZV4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

471857:SVIR RS04315
gene id: 471857:SVIR_RS04315
uniprot id: C7MXD8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

471857:SVIR RS16220
gene id: 471857:SVIR_RS16220
uniprot id: C7MZQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS01585
gene id: 471857:SVIR_RS01585
uniprot id: C7MTD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS03210
gene id: 471857:SVIR_RS03210
uniprot id: C7MVK8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471857:SVIR RS00885
gene id: 471857:SVIR_RS00885
uniprot id: C7MSF3
names: Similarity
messages: Belongs to the sigma-70 factor family.

471857:SVIR RS05705
gene id: 471857:SVIR_RS05705
uniprot id: C7MZV7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

471857:SVIR RS18345
gene id: 471857:SVIR_RS18345
uniprot id: C7MRA3
names: Similarity
messages: Belongs to the NodU/CmcH family.

471857:SVIR RS19755
gene id: 471857:SVIR_RS19755
uniprot id: C7MTW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

471857:SVIR RS10940
gene id: 471857:SVIR_RS10940
uniprot id: C7MXH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

471857:SVIR RS04835
gene id: 471857:SVIR_RS04835
uniprot id: C7MYA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

471857:SVIR RS12530
gene id: 471857:SVIR_RS12530
uniprot id: C7N023
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

471857:SVIR RS11035
gene id: 471857:SVIR_RS11035
uniprot id: C7MXJ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS18845
gene id: 471857:SVIR_RS18845
uniprot id: C7MRK3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS03820
gene id: 471857:SVIR_RS03820
uniprot id: C7MWI7
names: Similarity
messages: Belongs to the peptidase C40 family.

471857:SVIR RS07430
gene id: 471857:SVIR_RS07430
uniprot id: C7MSG4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

471857:SVIR RS13315
gene id: 471857:SVIR_RS13315
uniprot id: C7MV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

471857:SVIR RS15580
gene id: 471857:SVIR_RS15580
uniprot id: C7MYS0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

471857:SVIR RS12310
gene id: 471857:SVIR_RS12310
uniprot id: C7MZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

471857:SVIR RS13770
gene id: 471857:SVIR_RS13770
uniprot id: C7MVH2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

471857:SVIR RS11235
gene id: 471857:SVIR_RS11235
uniprot id: C7MXN2
names: Similarity
messages: Belongs to the CdaR family.

471857:SVIR RS06515
gene id: 471857:SVIR_RS06515
uniprot id: C7MQ82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

471857:SVIR RS15130
gene id: 471857:SVIR_RS15130
uniprot id: C7MXZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

471857:SVIR RS00820
gene id: 471857:SVIR_RS00820
uniprot id: C7MSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS15845
gene id: 471857:SVIR_RS15845
uniprot id: C7MZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

471857:SVIR RS01530
gene id: 471857:SVIR_RS01530
uniprot id: C7MTC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

471857:SVIR RS02825
gene id: 471857:SVIR_RS02825
uniprot id: C7MUT5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS17445
gene id: 471857:SVIR_RS17445
uniprot id: C7MQJ1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

471857:SVIR RS19440
gene id: 471857:SVIR_RS19440
uniprot id: C7MS50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS15825
gene id: 471857:SVIR_RS15825
uniprot id: C7MZH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS14210
gene id: 471857:SVIR_RS14210
uniprot id: C7MWB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

471857:SVIR RS19430
gene id: 471857:SVIR_RS19430
uniprot id: C7MS48
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02425
gene id: 471857:SVIR_RS02425
uniprot id: C7MU40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

471857:SVIR RS12425
gene id: 471857:SVIR_RS12425
uniprot id: C7N005
names: Similarity
messages: Belongs to the TlyA family.

471857:SVIR RS04410
gene id: 471857:SVIR_RS04410
uniprot id: C7MXF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

471857:SVIR RS09665
gene id: 471857:SVIR_RS09665
uniprot id: C7MV50
names: Similarity
messages: Belongs to the peptidase S66 family.

471857:SVIR RS18450
gene id: 471857:SVIR_RS18450
uniprot id: C7MRC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

471857:SVIR RS08780
gene id: 471857:SVIR_RS08780
uniprot id: C7MTU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

471857:SVIR RS02640
gene id: 471857:SVIR_RS02640
uniprot id: C7MUQ0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

471857:SVIR RS08065
gene id: 471857:SVIR_RS08065
uniprot id: C7MT52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

471857:SVIR RS18545
gene id: 471857:SVIR_RS18545
uniprot id: C7MRE3
names: Subcellular Location Annotation
messages: Cytoplasm

471857:SVIR RS07325
gene id: 471857:SVIR_RS07325
uniprot id: C7MQZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

471857:SVIR RS02485
gene id: 471857:SVIR_RS02485
uniprot id: C7MU52
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

471857:SVIR RS05315
gene id: 471857:SVIR_RS05315
uniprot id: C7MZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

471857:SVIR RS15930
gene id: 471857:SVIR_RS15930
uniprot id: C7MZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS13180
gene id: 471857:SVIR_RS13180
uniprot id: C7MUK8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

471857:SVIR RS19475
gene id: 471857:SVIR_RS19475
uniprot id: C7MS57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

471857:SVIR RS09550
gene id: 471857:SVIR_RS09550
uniprot id: C7MV27
names: Similarity
messages: Belongs to the transposase 7 family.

471857:SVIR RS06755
gene id: 471857:SVIR_RS06755
uniprot id: C7MQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

471857:SVIR RS14235
gene id: 471857:SVIR_RS14235
uniprot id: C7MWC4
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS06620
gene id: 471857:SVIR_RS06620
uniprot id: C7MQA3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

471857:SVIR RS06520
gene id: 471857:SVIR_RS06520
uniprot id: C7MQ83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS03755
gene id: 471857:SVIR_RS03755
uniprot id: C7MWH4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

471857:SVIR RS10270
gene id: 471857:SVIR_RS10270
uniprot id: C7MW22
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

471857:SVIR RS14365
gene id: 471857:SVIR_RS14365
uniprot id: C7MX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS09230
gene id: 471857:SVIR_RS09230
uniprot id: C7MUD6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

471857:SVIR RS19120
gene id: 471857:SVIR_RS19120
uniprot id: C7MRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS10445
gene id: 471857:SVIR_RS10445
uniprot id: C7MWQ2
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07765
gene id: 471857:SVIR_RS07765
uniprot id: C7MSN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS03425
gene id: 471857:SVIR_RS03425
uniprot id: C7MVQ2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

471857:SVIR RS05740
gene id: 471857:SVIR_RS05740
uniprot id: C7MZW2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

471857:SVIR RS03620
gene id: 471857:SVIR_RS03620
uniprot id: C7MWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

471857:SVIR RS04755
gene id: 471857:SVIR_RS04755
uniprot id: C7MY85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

471857:SVIR RS15420
gene id: 471857:SVIR_RS15420
uniprot id: C7MYN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

471857:SVIR RS05265
gene id: 471857:SVIR_RS05265
uniprot id: C7MZ14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS06800
gene id: 471857:SVIR_RS06800
uniprot id: C7MQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

471857:SVIR RS05420
gene id: 471857:SVIR_RS05420
uniprot id: C7MZ47
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

471857:SVIR RS16905
gene id: 471857:SVIR_RS16905
uniprot id: C7MPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

471857:SVIR RS01375
gene id: 471857:SVIR_RS01375
uniprot id: C7MT00
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

471857:SVIR RS10280
gene id: 471857:SVIR_RS10280
uniprot id: C7MW24
names: Similarity
messages: Belongs to the catalase family.

471857:SVIR RS15830
gene id: 471857:SVIR_RS15830
uniprot id: C7MZH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

471857:SVIR RS07515
gene id: 471857:SVIR_RS07515
uniprot id: C7MSI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

471857:SVIR RS00250
gene id: 471857:SVIR_RS00250
uniprot id: C7MRS8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

471857:SVIR RS11065
gene id: 471857:SVIR_RS11065
uniprot id: C7MXJ8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS15535
gene id: 471857:SVIR_RS15535
uniprot id: C7MYR1
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS15695
gene id: 471857:SVIR_RS15695
uniprot id: C7MYU4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471857:SVIR RS11090
gene id: 471857:SVIR_RS11090
uniprot id: C7MXK3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

471857:SVIR RS01975
gene id: 471857:SVIR_RS01975
uniprot id: C7MTK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

471857:SVIR RS10600
gene id: 471857:SVIR_RS10600
uniprot id: C7MWS9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02830
gene id: 471857:SVIR_RS02830
uniprot id: C7MUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

471857:SVIR RS11220
gene id: 471857:SVIR_RS11220
uniprot id: C7MXM9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS13850
gene id: 471857:SVIR_RS13850
uniprot id: C7MW48
names: Cofactor
messages: Can also use Mn(2+) ion.

471857:SVIR RS02020
gene id: 471857:SVIR_RS02020
uniprot id: C7MTV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

471857:SVIR RS14640
gene id: 471857:SVIR_RS14640
uniprot id: C7MX57
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

471857:SVIR RS04250
gene id: 471857:SVIR_RS04250
uniprot id: C7MXC5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

471857:SVIR RS08615
gene id: 471857:SVIR_RS08615
uniprot id: C7MTR3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

471857:SVIR RS07510
gene id: 471857:SVIR_RS07510
uniprot id: C7MSI0
names: Similarity
messages: Belongs to the peptidase A24 family.

471857:SVIR RS13985
gene id: 471857:SVIR_RS13985
uniprot id: C7MW76
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

471857:SVIR RS15095
gene id: 471857:SVIR_RS15095
uniprot id: C7MXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

471857:SVIR RS00230
gene id: 471857:SVIR_RS00230
uniprot id: C7MRS4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

471857:SVIR RS02945
gene id: 471857:SVIR_RS02945
uniprot id: C7MUV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS07355
gene id: 471857:SVIR_RS07355
uniprot id: C7MR01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS02405
gene id: 471857:SVIR_RS02405
uniprot id: C7MU36
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

471857:SVIR RS14060
gene id: 471857:SVIR_RS14060
uniprot id: C7MW89
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

471857:SVIR RS11885
gene id: 471857:SVIR_RS11885
uniprot id: C7MYL1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

471857:SVIR RS16845
gene id: 471857:SVIR_RS16845
uniprot id: C7MPY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

471857:SVIR RS17325
gene id: 471857:SVIR_RS17325
uniprot id: C7MQ73
names: Similarity
messages: Belongs to the peptidase M1 family.

471857:SVIR RS01415
gene id: 471857:SVIR_RS01415
uniprot id: C7MT08
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

471857:SVIR RS06575
gene id: 471857:SVIR_RS06575
uniprot id: C7MQ94
names: Similarity
messages: Belongs to the peptidase S8 family.

471857:SVIR RS15380
gene id: 471857:SVIR_RS15380
uniprot id: C7MYN0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

471857:SVIR RS03445
gene id: 471857:SVIR_RS03445
uniprot id: C7MVQ6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

471857:SVIR RS15810
gene id: 471857:SVIR_RS15810
uniprot id: C7MZH6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04180
gene id: 471857:SVIR_RS04180
uniprot id: C7MXB1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

471857:SVIR RS07620
gene id: 471857:SVIR_RS07620
uniprot id: C7MSK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

471857:SVIR RS19155
gene id: 471857:SVIR_RS19155
uniprot id: C7MRZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS05070
gene id: 471857:SVIR_RS05070
uniprot id: C7MYX5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS01575
gene id: 471857:SVIR_RS01575
uniprot id: C7MTD1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

471857:SVIR RS15500
gene id: 471857:SVIR_RS15500
uniprot id: C7MYQ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS14780
gene id: 471857:SVIR_RS14780
uniprot id: C7MXS2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS04475
gene id: 471857:SVIR_RS04475
uniprot id: C7MY29
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

471857:SVIR RS13430
gene id: 471857:SVIR_RS13430
uniprot id: C7MVA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS15210
gene id: 471857:SVIR_RS15210
uniprot id: C7MY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS06165
gene id: 471857:SVIR_RS06165
uniprot id: C7MPR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

471857:SVIR RS13920
gene id: 471857:SVIR_RS13920
uniprot id: C7MW63
names: Similarity
messages: Belongs to the UPF0045 family.

471857:SVIR RS13750
gene id: 471857:SVIR_RS13750
uniprot id: C7MVG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

471857:SVIR RS13400
gene id: 471857:SVIR_RS13400
uniprot id: C7MV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

471857:SVIR RS14530
gene id: 471857:SVIR_RS14530
uniprot id: C7MX35
names: Similarity
messages: Belongs to the fabD family.

471857:SVIR RS06665
gene id: 471857:SVIR_RS06665
uniprot id: C7MQB2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

471857:SVIR RS07365
gene id: 471857:SVIR_RS07365
uniprot id: C7MR03
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS09305
gene id: 471857:SVIR_RS09305
uniprot id: C7MUF2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

471857:SVIR RS03075
gene id: 471857:SVIR_RS03075
uniprot id: C7MVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

471857:SVIR RS04825
gene id: 471857:SVIR_RS04825
uniprot id: C7MY99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

471857:SVIR RS09200
gene id: 471857:SVIR_RS09200
uniprot id: C7MUD0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

471857:SVIR RS12465
gene id: 471857:SVIR_RS12465
uniprot id: C7N010
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

471857:SVIR RS12185
gene id: 471857:SVIR_RS12185
uniprot id: C7MZC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

471857:SVIR RS02110
gene id: 471857:SVIR_RS02110
uniprot id: C7MTX6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

471857:SVIR RS04425
gene id: 471857:SVIR_RS04425
uniprot id: C7MXF8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471857:SVIR RS13480
gene id: 471857:SVIR_RS13480
uniprot id: C7MVB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

471857:SVIR RS16635
gene id: 471857:SVIR_RS16635
uniprot id: C7N0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

471857:SVIR RS04930
gene id: 471857:SVIR_RS04930
uniprot id: C7MYC0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS02060
gene id: 471857:SVIR_RS02060
uniprot id: C7MTW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

471857:SVIR RS06310
gene id: 471857:SVIR_RS06310
uniprot id: C7MPU5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

471857:SVIR RS18550
gene id: 471857:SVIR_RS18550
uniprot id: C7MRE4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

471857:SVIR RS04690
gene id: 471857:SVIR_RS04690
uniprot id: C7MY72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS16750
gene id: 471857:SVIR_RS16750
uniprot id: C7N0I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

471857:SVIR RS02005
gene id: 471857:SVIR_RS02005
uniprot id: C7MTL3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

471857:SVIR RS05190
gene id: 471857:SVIR_RS05190
uniprot id: C7MYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

471857:SVIR RS01315
gene id: 471857:SVIR_RS01315
uniprot id: C7MSY8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

471857:SVIR RS01775
gene id: 471857:SVIR_RS01775
uniprot id: C7MTG8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS15690
gene id: 471857:SVIR_RS15690
uniprot id: C7MYU3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

471857:SVIR RS02025
gene id: 471857:SVIR_RS02025
uniprot id: C7MTV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

471857:SVIR RS06560
gene id: 471857:SVIR_RS06560
uniprot id: C7MQ91
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

471857:SVIR RS13540
gene id: 471857:SVIR_RS13540
uniprot id: C7MVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS02815
gene id: 471857:SVIR_RS02815
uniprot id: C7MUT3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

471857:SVIR RS06700
gene id: 471857:SVIR_RS06700
uniprot id: C7MQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS05180
gene id: 471857:SVIR_RS05180
uniprot id: C7MYZ7
names: Similarity
messages: Belongs to the asparagine synthetase family.

471857:SVIR RS04105
gene id: 471857:SVIR_RS04105
uniprot id: C7MX95
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

471857:SVIR RS12180
gene id: 471857:SVIR_RS12180
uniprot id: C7MZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

471857:SVIR RS05520
gene id: 471857:SVIR_RS05520
uniprot id: C7MZS0
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

471857:SVIR RS02445
gene id: 471857:SVIR_RS02445
uniprot id: C7MU44
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

471857:SVIR RS07745
gene id: 471857:SVIR_RS07745
uniprot id: C7MSM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

471857:SVIR RS03065
gene id: 471857:SVIR_RS03065
uniprot id: C7MVH7
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

471857:SVIR RS08165
gene id: 471857:SVIR_RS08165
uniprot id: C7MT72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS17955
gene id: 471857:SVIR_RS17955
uniprot id: C7MR32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

471857:SVIR RS05375
gene id: 471857:SVIR_RS05375
uniprot id: C7MZ38
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07245
gene id: 471857:SVIR_RS07245
uniprot id: C7MQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

471857:SVIR RS05695
gene id: 471857:SVIR_RS05695
uniprot id: C7MZV5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

471857:SVIR RS19010
gene id: 471857:SVIR_RS19010
uniprot id: C7MRW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

471857:SVIR RS13905
gene id: 471857:SVIR_RS13905
uniprot id: C7MW60
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

471857:SVIR RS17470
gene id: 471857:SVIR_RS17470
uniprot id: C7MQJ6
names: Similarity
messages: Belongs to the EspG family.

471857:SVIR RS06320
gene id: 471857:SVIR_RS06320
uniprot id: C7MPU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

471857:SVIR RS04895
gene id: 471857:SVIR_RS04895
uniprot id: C7MYB3
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS06615
gene id: 471857:SVIR_RS06615
uniprot id: C7MQA2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

471857:SVIR RS11050
gene id: 471857:SVIR_RS11050
uniprot id: C7MXJ5
names: Similarity
messages: Belongs to the group II decarboxylase family.

471857:SVIR RS00745
gene id: 471857:SVIR_RS00745
uniprot id: C7MSC6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS03190
gene id: 471857:SVIR_RS03190
uniprot id: C7MVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS09505
gene id: 471857:SVIR_RS09505
uniprot id: C7MV18
names: Similarity
messages: Belongs to the peptidase S1 family.

471857:SVIR RS11790
gene id: 471857:SVIR_RS11790
uniprot id: C7MYJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

471857:SVIR RS10570
gene id: 471857:SVIR_RS10570
uniprot id: C7MWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

471857:SVIR RS02615
gene id: 471857:SVIR_RS02615
uniprot id: C7MUP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

471857:SVIR RS08710
gene id: 471857:SVIR_RS08710
uniprot id: C7MTT1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS07520
gene id: 471857:SVIR_RS07520
uniprot id: C7MSI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS13520
gene id: 471857:SVIR_RS13520
uniprot id: C7MVC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS12135
gene id: 471857:SVIR_RS12135
uniprot id: C7MZB5
names: Similarity
messages: Belongs to the arsA ATPase family.

471857:SVIR RS16300
gene id: 471857:SVIR_RS16300
uniprot id: C7MZR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

471857:SVIR RS17305
gene id: 471857:SVIR_RS17305
uniprot id: C7MQ69
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

471857:SVIR RS02440
gene id: 471857:SVIR_RS02440
uniprot id: C7MU43
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS00020
gene id: 471857:SVIR_RS00020
uniprot id: C7MRN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

471857:SVIR RS01355
gene id: 471857:SVIR_RS01355
uniprot id: C7MSZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

471857:SVIR RS15070
gene id: 471857:SVIR_RS15070
uniprot id: C7MXY1
names: Similarity
messages: Belongs to the EspG family.

471857:SVIR RS10100
gene id: 471857:SVIR_RS10100
uniprot id: C7MVY8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS11295
gene id: 471857:SVIR_RS11295
uniprot id: C7MXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS07610
gene id: 471857:SVIR_RS07610
uniprot id: C7MSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

471857:SVIR RS12845
gene id: 471857:SVIR_RS12845
uniprot id: C7N083
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS12020
gene id: 471857:SVIR_RS12020
uniprot id: C7MZ90
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

471857:SVIR RS07730
gene id: 471857:SVIR_RS07730
uniprot id: C7MSM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS12060
gene id: 471857:SVIR_RS12060
uniprot id: C7MZ99
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS09240
gene id: 471857:SVIR_RS09240
uniprot id: C7MUD8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS15925
gene id: 471857:SVIR_RS15925
uniprot id: C7MZJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

471857:SVIR RS09005
gene id: 471857:SVIR_RS09005
uniprot id: C7MU92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471857:SVIR RS00705
gene id: 471857:SVIR_RS00705
uniprot id: C7MSB8
names: Similarity
messages: Belongs to the EspG family.

471857:SVIR RS13820
gene id: 471857:SVIR_RS13820
uniprot id: C7MW42
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

471857:SVIR RS16495
gene id: 471857:SVIR_RS16495
uniprot id: C7N0D2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471857:SVIR RS07330
gene id: 471857:SVIR_RS07330
uniprot id: C7MQZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

471857:SVIR RS10895
gene id: 471857:SVIR_RS10895
uniprot id: C7MXG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS01280
gene id: 471857:SVIR_RS01280
uniprot id: C7MSY1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

471857:SVIR RS10785
gene id: 471857:SVIR_RS10785
uniprot id: C7MWW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

471857:SVIR RS09890
gene id: 471857:SVIR_RS09890
uniprot id: C7MVU7
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07140
gene id: 471857:SVIR_RS07140
uniprot id: C7MQW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

471857:SVIR RS14930
gene id: 471857:SVIR_RS14930
uniprot id: C7MXV3
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS18740
gene id: 471857:SVIR_RS18740
uniprot id: C7MRI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

471857:SVIR RS13595
gene id: 471857:SVIR_RS13595
uniprot id: C7MVD6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

471857:SVIR RS03615
gene id: 471857:SVIR_RS03615
uniprot id: C7MWE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS14755
gene id: 471857:SVIR_RS14755
uniprot id: C7MX77
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS05120
gene id: 471857:SVIR_RS05120
uniprot id: C7MYY5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

471857:SVIR RS16200
gene id: 471857:SVIR_RS16200
uniprot id: C7MZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

471857:SVIR RS18355
gene id: 471857:SVIR_RS18355
uniprot id: C7MRA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

471857:SVIR RS02350
gene id: 471857:SVIR_RS02350
uniprot id: C7MU25
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS05495
gene id: 471857:SVIR_RS05495
uniprot id: C7MZ62
names: Similarity
messages: Belongs to the NodU/CmcH family.

471857:SVIR RS14580
gene id: 471857:SVIR_RS14580
uniprot id: C7MX45
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

471857:SVIR RS02975
gene id: 471857:SVIR_RS02975
uniprot id: C7MUW5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

471857:SVIR RS01995
gene id: 471857:SVIR_RS01995
uniprot id: C7MTL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

471857:SVIR RS14185
gene id: 471857:SVIR_RS14185
uniprot id: C7MWB4
names: Subcellular Location Annotation
messages: Cytoplasm

471857:SVIR RS01405
gene id: 471857:SVIR_RS01405
uniprot id: C7MT06
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

471857:SVIR RS00015
gene id: 471857:SVIR_RS00015
uniprot id: C7MRN5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

471857:SVIR RS08375
gene id: 471857:SVIR_RS08375
uniprot id: C7MTL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

471857:SVIR RS09110
gene id: 471857:SVIR_RS09110
uniprot id: C7MUB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS01990
gene id: 471857:SVIR_RS01990
uniprot id: C7MTL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

471857:SVIR RS06110
gene id: 471857:SVIR_RS06110
uniprot id: C7MPQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS04760
gene id: 471857:SVIR_RS04760
uniprot id: C7MY86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

471857:SVIR RS14275
gene id: 471857:SVIR_RS14275
uniprot id: C7MWD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

471857:SVIR RS04795
gene id: 471857:SVIR_RS04795
uniprot id: C7MY93
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

471857:SVIR RS12355
gene id: 471857:SVIR_RS12355
uniprot id: C7MZG0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

471857:SVIR RS08930
gene id: 471857:SVIR_RS08930
uniprot id: C7MU77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471857:SVIR RS16890
gene id: 471857:SVIR_RS16890
uniprot id: C7MPY9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

471857:SVIR RS11840
gene id: 471857:SVIR_RS11840
uniprot id: C7MYK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

471857:SVIR RS02780
gene id: 471857:SVIR_RS02780
uniprot id: C7MUS5
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

471857:SVIR RS13565
gene id: 471857:SVIR_RS13565
uniprot id: C7MVD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

471857:SVIR RS15390
gene id: 471857:SVIR_RS15390
uniprot id: C7MYN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

471857:SVIR RS08765
gene id: 471857:SVIR_RS08765
uniprot id: C7MTU0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS11055
gene id: 471857:SVIR_RS11055
uniprot id: C7MXJ6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS18590
gene id: 471857:SVIR_RS18590
uniprot id: C7MRF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

471857:SVIR RS00980
gene id: 471857:SVIR_RS00980
uniprot id: C7MSS1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471857:SVIR RS08490
gene id: 471857:SVIR_RS08490
uniprot id: C7MTN8
names: Similarity
messages: Belongs to the peptidase S58 family.

471857:SVIR RS02345
gene id: 471857:SVIR_RS02345
uniprot id: C7MU24
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

471857:SVIR RS08550
gene id: 471857:SVIR_RS08550
uniprot id: C7MTQ0
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS05290
gene id: 471857:SVIR_RS05290
uniprot id: C7MZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

471857:SVIR RS12260
gene id: 471857:SVIR_RS12260
uniprot id: C7MZE0
names: Similarity
messages: Belongs to the PspA/IM30 family.

471857:SVIR RS00145
gene id: 471857:SVIR_RS00145
uniprot id: C7MRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

471857:SVIR RS12415
gene id: 471857:SVIR_RS12415
uniprot id: C7N003
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

471857:SVIR RS09370
gene id: 471857:SVIR_RS09370
uniprot id: C7MUZ1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

471857:SVIR RS03460
gene id: 471857:SVIR_RS03460
uniprot id: C7MVQ9
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

471857:SVIR RS10680
gene id: 471857:SVIR_RS10680
uniprot id: C7MWU5
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

471857:SVIR RS15770
gene id: 471857:SVIR_RS15770
uniprot id: C7MZG8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

471857:SVIR RS05490
gene id: 471857:SVIR_RS05490
uniprot id: C7MZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

471857:SVIR RS00005
gene id: 471857:SVIR_RS00005
uniprot id: C7MRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

471857:SVIR RS17625
gene id: 471857:SVIR_RS17625
uniprot id: C7MQM7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

471857:SVIR RS19270
gene id: 471857:SVIR_RS19270
uniprot id: C7MS17
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

471857:SVIR RS04255
gene id: 471857:SVIR_RS04255
uniprot id: C7MXC6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

471857:SVIR RS12075
gene id: 471857:SVIR_RS12075
uniprot id: C7MZA3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

471857:SVIR RS16755
gene id: 471857:SVIR_RS16755
uniprot id: C7N0I3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

471857:SVIR RS09820
gene id: 471857:SVIR_RS09820
uniprot id: C7MVT3
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS11505
gene id: 471857:SVIR_RS11505
uniprot id: C7MYE4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS16895
gene id: 471857:SVIR_RS16895
uniprot id: C7MPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

471857:SVIR RS15545
gene id: 471857:SVIR_RS15545
uniprot id: C7MYR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

471857:SVIR RS03095
gene id: 471857:SVIR_RS03095
uniprot id: C7MVI3
names: Similarity
messages: Belongs to the LOG family.

471857:SVIR RS10955
gene id: 471857:SVIR_RS10955
uniprot id: C7MXH6
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

471857:SVIR RS07870
gene id: 471857:SVIR_RS07870
uniprot id: C7MSQ3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

471857:SVIR RS17850
gene id: 471857:SVIR_RS17850
uniprot id: C7MQS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471857:SVIR RS01605
gene id: 471857:SVIR_RS01605
uniprot id: C7MTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS14175
gene id: 471857:SVIR_RS14175
uniprot id: C7MWB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

471857:SVIR RS12275
gene id: 471857:SVIR_RS12275
uniprot id: C7MZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

471857:SVIR RS11910
gene id: 471857:SVIR_RS11910
uniprot id: C7MZ68
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02785
gene id: 471857:SVIR_RS02785
uniprot id: C7MUS6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

471857:SVIR RS04035
gene id: 471857:SVIR_RS04035
uniprot id: C7MWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

471857:SVIR RS14420
gene id: 471857:SVIR_RS14420
uniprot id: C7MX13
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

471857:SVIR RS10665
gene id: 471857:SVIR_RS10665
uniprot id: C7MWU2
names: Similarity
messages: Belongs to the peptidase M24B family.

471857:SVIR RS19200
gene id: 471857:SVIR_RS19200
uniprot id: C7MS03
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02035
gene id: 471857:SVIR_RS02035
uniprot id: C7MTW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

471857:SVIR RS02165
gene id: 471857:SVIR_RS02165
uniprot id: C7MTY9
names: Similarity
messages: Belongs to the WXG100 family.

471857:SVIR RS06975
gene id: 471857:SVIR_RS06975
uniprot id: C7MQS8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

471857:SVIR RS17345
gene id: 471857:SVIR_RS17345
uniprot id: C7MQH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS14970
gene id: 471857:SVIR_RS14970
uniprot id: C7MXW1
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

471857:SVIR RS04460
gene id: 471857:SVIR_RS04460
uniprot id: C7MY26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

471857:SVIR RS01795
gene id: 471857:SVIR_RS01795
uniprot id: C7MTH1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

471857:SVIR RS12895
gene id: 471857:SVIR_RS12895
uniprot id: C7MUF5
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04155
gene id: 471857:SVIR_RS04155
uniprot id: C7MXA5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

471857:SVIR RS11800
gene id: 471857:SVIR_RS11800
uniprot id: C7MYJ4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

471857:SVIR RS12280
gene id: 471857:SVIR_RS12280
uniprot id: C7MZE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

471857:SVIR RS14770
gene id: 471857:SVIR_RS14770
uniprot id: C7MX81
names: Similarity
messages: Belongs to the TPP enzyme family.

471857:SVIR RS15905
gene id: 471857:SVIR_RS15905
uniprot id: C7MZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

471857:SVIR RS13800
gene id: 471857:SVIR_RS13800
uniprot id: C7MW38
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

471857:SVIR RS13045
gene id: 471857:SVIR_RS13045
uniprot id: C7MUI1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS02010
gene id: 471857:SVIR_RS02010
uniprot id: C7MTL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

471857:SVIR RS10335
gene id: 471857:SVIR_RS10335
uniprot id: C7MW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

471857:SVIR RS18935
gene id: 471857:SVIR_RS18935
uniprot id: C7MRM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS02650
gene id: 471857:SVIR_RS02650
uniprot id: C7MUQ2
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS15450
gene id: 471857:SVIR_RS15450
uniprot id: C7MYP4
names: Similarity
messages: Belongs to the EspG family.

471857:SVIR RS01945
gene id: 471857:SVIR_RS01945
uniprot id: C7MTK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

471857:SVIR RS02955
gene id: 471857:SVIR_RS02955
uniprot id: C7MUW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS07145
gene id: 471857:SVIR_RS07145
uniprot id: C7MQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

471857:SVIR RS17655
gene id: 471857:SVIR_RS17655
uniprot id: C7MQN3
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS16290
gene id: 471857:SVIR_RS16290
uniprot id: C7MZR4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

471857:SVIR RS14945
gene id: 471857:SVIR_RS14945
uniprot id: C7MXV6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

471857:SVIR RS03130
gene id: 471857:SVIR_RS03130
uniprot id: C7MVJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

471857:SVIR RS16435
gene id: 471857:SVIR_RS16435
uniprot id: C7N0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

471857:SVIR RS11990
gene id: 471857:SVIR_RS11990
uniprot id: C7MZ84
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS12965
gene id: 471857:SVIR_RS12965
uniprot id: C7MUG9
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

471857:SVIR RS10945
gene id: 471857:SVIR_RS10945
uniprot id: C7MXH4
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

471857:SVIR RS02940
gene id: 471857:SVIR_RS02940
uniprot id: C7MUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

471857:SVIR RS07735
gene id: 471857:SVIR_RS07735
uniprot id: C7MSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

471857:SVIR RS16830
gene id: 471857:SVIR_RS16830
uniprot id: C7N0J8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

471857:SVIR RS07775
gene id: 471857:SVIR_RS07775
uniprot id: C7MSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

471857:SVIR RS17600
gene id: 471857:SVIR_RS17600
uniprot id: C7MQM2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

471857:SVIR RS04005
gene id: 471857:SVIR_RS04005
uniprot id: C7MWM4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

471857:SVIR RS04975
gene id: 471857:SVIR_RS04975
uniprot id: C7MYD0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

471857:SVIR RS03630
gene id: 471857:SVIR_RS03630
uniprot id: C7MWF2
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

471857:SVIR RS11155
gene id: 471857:SVIR_RS11155
uniprot id: C7MXL6
names: Similarity
messages: Belongs to the universal stress protein A family.

471857:SVIR RS07095
gene id: 471857:SVIR_RS07095
uniprot id: C7MQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

471857:SVIR RS11070
gene id: 471857:SVIR_RS11070
uniprot id: C7MXJ9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

471857:SVIR RS02030
gene id: 471857:SVIR_RS02030
uniprot id: C7MTW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

471857:SVIR RS13955
gene id: 471857:SVIR_RS13955
uniprot id: C7MW70
names: Similarity
messages: Belongs to the universal stress protein A family.

471857:SVIR RS16205
gene id: 471857:SVIR_RS16205
uniprot id: C7MZP7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

471857:SVIR RS07115
gene id: 471857:SVIR_RS07115
uniprot id: C7MQV7
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02740
gene id: 471857:SVIR_RS02740
uniprot id: C7MUR7
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04305
gene id: 471857:SVIR_RS04305
uniprot id: C7MXD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS03910
gene id: 471857:SVIR_RS03910
uniprot id: C7MWK4
names: Similarity
messages: Belongs to the HypE family.

471857:SVIR RS12030
gene id: 471857:SVIR_RS12030
uniprot id: C7MZ92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS02000
gene id: 471857:SVIR_RS02000
uniprot id: C7MTL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

471857:SVIR RS03455
gene id: 471857:SVIR_RS03455
uniprot id: C7MVQ8
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS07215
gene id: 471857:SVIR_RS07215
uniprot id: C7MQX7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

471857:SVIR RS15010
gene id: 471857:SVIR_RS15010
uniprot id: C7MXW9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

471857:SVIR RS16155
gene id: 471857:SVIR_RS16155
uniprot id: C7MZN9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS15835
gene id: 471857:SVIR_RS15835
uniprot id: C7MZI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

471857:SVIR RS14435
gene id: 471857:SVIR_RS14435
uniprot id: C7MX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

471857:SVIR RS14550
gene id: 471857:SVIR_RS14550
uniprot id: C7MX39
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471857:SVIR RS02665
gene id: 471857:SVIR_RS02665
uniprot id: C7MUQ5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

471857:SVIR RS03390
gene id: 471857:SVIR_RS03390
uniprot id: C7MVP5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

471857:SVIR RS01595
gene id: 471857:SVIR_RS01595
uniprot id: C7MTD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS13815
gene id: 471857:SVIR_RS13815
uniprot id: C7MW41
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

471857:SVIR RS13350
gene id: 471857:SVIR_RS13350
uniprot id: C7MV87
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

471857:SVIR RS08090
gene id: 471857:SVIR_RS08090
uniprot id: C7MT57
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

471857:SVIR RS10705
gene id: 471857:SVIR_RS10705
uniprot id: C7MWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

471857:SVIR RS04685
gene id: 471857:SVIR_RS04685
uniprot id: C7MY71
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

471857:SVIR RS04500
gene id: 471857:SVIR_RS04500
uniprot id: C7MY34
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

471857:SVIR RS07575
gene id: 471857:SVIR_RS07575
uniprot id: C7MSJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

471857:SVIR RS06640
gene id: 471857:SVIR_RS06640
uniprot id: C7MQA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

471857:SVIR RS01420
gene id: 471857:SVIR_RS01420
uniprot id: C7MT09
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

471857:SVIR RS14340
gene id: 471857:SVIR_RS14340
uniprot id: C7MWZ7
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

471857:SVIR RS02755
gene id: 471857:SVIR_RS02755
uniprot id: C7MUS0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

471857:SVIR RS04605
gene id: 471857:SVIR_RS04605
uniprot id: C7MY54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

471857:SVIR RS16210
gene id: 471857:SVIR_RS16210
uniprot id: C7MZP8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

471857:SVIR RS20025
gene id: 471857:SVIR_RS20025
uniprot id: C7MXW7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

471857:SVIR RS13570
gene id: 471857:SVIR_RS13570
uniprot id: C7MVD1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

471857:SVIR RS04065
gene id: 471857:SVIR_RS04065
uniprot id: C7MX86
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS02925
gene id: 471857:SVIR_RS02925
uniprot id: C7MUV5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

471857:SVIR RS01400
gene id: 471857:SVIR_RS01400
uniprot id: C7MT05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

471857:SVIR RS16875
gene id: 471857:SVIR_RS16875
uniprot id: C7MPY6
names: Subcellular Location Annotation
messages: Cytoplasm

471857:SVIR RS00645
gene id: 471857:SVIR_RS00645
uniprot id: C7MSA6
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

471857:SVIR RS16230
gene id: 471857:SVIR_RS16230
uniprot id: C7MZQ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS06735
gene id: 471857:SVIR_RS06735
uniprot id: C7MQC6
names: Similarity
messages: Belongs to the serpin family.

471857:SVIR RS09625
gene id: 471857:SVIR_RS09625
uniprot id: C7MV42
names: Similarity
messages: Belongs to the YciI family.

471857:SVIR RS12835
gene id: 471857:SVIR_RS12835
uniprot id: C7N081
names: Similarity
messages: Belongs to the CdaR family.

471857:SVIR RS06350
gene id: 471857:SVIR_RS06350
uniprot id: C7MPV3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

471857:SVIR RS03890
gene id: 471857:SVIR_RS03890
uniprot id: C7MWK0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

471857:SVIR RS08955
gene id: 471857:SVIR_RS08955
uniprot id: C7MU82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS06710
gene id: 471857:SVIR_RS06710
uniprot id: C7MQC1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

471857:SVIR RS13795
gene id: 471857:SVIR_RS13795
uniprot id: C7MW37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

471857:SVIR RS15375
gene id: 471857:SVIR_RS15375
uniprot id: C7MYM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

471857:SVIR RS13930
gene id: 471857:SVIR_RS13930
uniprot id: C7MW65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS07175
gene id: 471857:SVIR_RS07175
uniprot id: C7MQW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS16250
gene id: 471857:SVIR_RS16250
uniprot id: C7MZQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS12460
gene id: 471857:SVIR_RS12460
uniprot id: C7N009
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS19315
gene id: 471857:SVIR_RS19315
uniprot id: C7MS26
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS15875
gene id: 471857:SVIR_RS15875
uniprot id: C7MZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

471857:SVIR RS01615
gene id: 471857:SVIR_RS01615
uniprot id: C7MTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

471857:SVIR RS01985
gene id: 471857:SVIR_RS01985
uniprot id: C7MTK9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

471857:SVIR RS01270
gene id: 471857:SVIR_RS01270
uniprot id: C7MSX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471857:SVIR RS02335
gene id: 471857:SVIR_RS02335
uniprot id: C7MU22
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

471857:SVIR RS18920
gene id: 471857:SVIR_RS18920
uniprot id: C7MRL8
names: Similarity
messages: Belongs to the UPF0098 family.

471857:SVIR RS19290
gene id: 471857:SVIR_RS19290
uniprot id: C7MS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

471857:SVIR RS15215
gene id: 471857:SVIR_RS15215
uniprot id: C7MY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS00395
gene id: 471857:SVIR_RS00395
uniprot id: C7MRV8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

471857:SVIR RS09500
gene id: 471857:SVIR_RS09500
uniprot id: C7MV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

471857:SVIR RS01305
gene id: 471857:SVIR_RS01305
uniprot id: C7MSY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

471857:SVIR RS00525
gene id: 471857:SVIR_RS00525
uniprot id: C7MS82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

471857:SVIR RS09235
gene id: 471857:SVIR_RS09235
uniprot id: C7MUD7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

471857:SVIR RS01265
gene id: 471857:SVIR_RS01265
uniprot id: C7MSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471857:SVIR RS15235
gene id: 471857:SVIR_RS15235
uniprot id: C7MY14
names: Similarity
messages: Belongs to the YciI family.

471857:SVIR RS00920
gene id: 471857:SVIR_RS00920
uniprot id: C7MSG0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

471857:SVIR RS04620
gene id: 471857:SVIR_RS04620
uniprot id: C7MY58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

471857:SVIR RS10885
gene id: 471857:SVIR_RS10885
uniprot id: C7MXG2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

471857:SVIR RS02290
gene id: 471857:SVIR_RS02290
uniprot id: C7MU13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

471857:SVIR RS11515
gene id: 471857:SVIR_RS11515
uniprot id: C7MYE6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS03660
gene id: 471857:SVIR_RS03660
uniprot id: C7MWF5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

471857:SVIR RS13990
gene id: 471857:SVIR_RS13990
uniprot id: C7MW77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

471857:SVIR RS18750
gene id: 471857:SVIR_RS18750
uniprot id: C7MRI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS08080
gene id: 471857:SVIR_RS08080
uniprot id: C7MT55
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS03150
gene id: 471857:SVIR_RS03150
uniprot id: C7MVJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS07070
gene id: 471857:SVIR_RS07070
uniprot id: C7MQU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

471857:SVIR RS14490
gene id: 471857:SVIR_RS14490
uniprot id: C7MX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

471857:SVIR RS05020
gene id: 471857:SVIR_RS05020
uniprot id: C7MYW6
names: Similarity
messages: Belongs to the CdaR family.

471857:SVIR RS17900
gene id: 471857:SVIR_RS17900
uniprot id: C7MR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

471857:SVIR RS12605
gene id: 471857:SVIR_RS12605
uniprot id: C7N038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

471857:SVIR RS00550
gene id: 471857:SVIR_RS00550
uniprot id: C7MS87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS09585
gene id: 471857:SVIR_RS09585
uniprot id: C7MV33
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

471857:SVIR RS17590
gene id: 471857:SVIR_RS17590
uniprot id: C7MQM0
names: Similarity
messages: Belongs to the GSP E family.

471857:SVIR RS09430
gene id: 471857:SVIR_RS09430
uniprot id: C7MV02
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

471857:SVIR RS00520
gene id: 471857:SVIR_RS00520
uniprot id: C7MS81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

471857:SVIR RS13720
gene id: 471857:SVIR_RS13720
uniprot id: C7MVG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

471857:SVIR RS04750
gene id: 471857:SVIR_RS04750
uniprot id: C7MY84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

471857:SVIR RS08890
gene id: 471857:SVIR_RS08890
uniprot id: C7MU69
names: Similarity
messages: Belongs to the YciI family.

471857:SVIR RS18255
gene id: 471857:SVIR_RS18255
uniprot id: C7MR87
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

471857:SVIR RS17400
gene id: 471857:SVIR_RS17400
uniprot id: C7MQI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS09205
gene id: 471857:SVIR_RS09205
uniprot id: C7MUD1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

471857:SVIR RS08260
gene id: 471857:SVIR_RS08260
uniprot id: C7MT90
names: Similarity
messages: Belongs to the thioredoxin family.

471857:SVIR RS15190
gene id: 471857:SVIR_RS15190
uniprot id: C7MY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS03740
gene id: 471857:SVIR_RS03740
uniprot id: C7MWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

471857:SVIR RS15400
gene id: 471857:SVIR_RS15400
uniprot id: C7MYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

471857:SVIR RS08505
gene id: 471857:SVIR_RS08505
uniprot id: C7MTP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS00905
gene id: 471857:SVIR_RS00905
uniprot id: C7MSF7
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

471857:SVIR RS12545
gene id: 471857:SVIR_RS12545
uniprot id: C7N026
names: Similarity
messages: Belongs to the RutC family.

471857:SVIR RS05150
gene id: 471857:SVIR_RS05150
uniprot id: C7MYZ1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS13875
gene id: 471857:SVIR_RS13875
uniprot id: C7MW53
names: Similarity
messages: Belongs to the peptidase C40 family.

471857:SVIR RS06915
gene id: 471857:SVIR_RS06915
uniprot id: C7MQG3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

471857:SVIR RS14485
gene id: 471857:SVIR_RS14485
uniprot id: C7MX26
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

471857:SVIR RS00475
gene id: 471857:SVIR_RS00475
uniprot id: C7MS72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

471857:SVIR RS02990
gene id: 471857:SVIR_RS02990
uniprot id: C7MUW8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

471857:SVIR RS19390
gene id: 471857:SVIR_RS19390
uniprot id: C7MS41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS02715
gene id: 471857:SVIR_RS02715
uniprot id: C7MUR4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

471857:SVIR RS17550
gene id: 471857:SVIR_RS17550
uniprot id: C7MQL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

471857:SVIR RS13845
gene id: 471857:SVIR_RS13845
uniprot id: C7MW47
names: Similarity
messages: Belongs to the malate synthase family.

471857:SVIR RS14310
gene id: 471857:SVIR_RS14310
uniprot id: C7MWZ1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

471857:SVIR RS04385
gene id: 471857:SVIR_RS04385
uniprot id: C7MXF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471857:SVIR RS00775
gene id: 471857:SVIR_RS00775
uniprot id: C7MSD2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

471857:SVIR RS14650
gene id: 471857:SVIR_RS14650
uniprot id: C7MX59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS03485
gene id: 471857:SVIR_RS03485
uniprot id: C7MVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS18715
gene id: 471857:SVIR_RS18715
uniprot id: C7MRH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

471857:SVIR RS11245
gene id: 471857:SVIR_RS11245
uniprot id: C7MXN4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS13785
gene id: 471857:SVIR_RS13785
uniprot id: C7MVH5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

471857:SVIR RS11695
gene id: 471857:SVIR_RS11695
uniprot id: C7MYH4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS00165
gene id: 471857:SVIR_RS00165
uniprot id: C7MRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS05025
gene id: 471857:SVIR_RS05025
uniprot id: C7MYW7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

471857:SVIR RS14750
gene id: 471857:SVIR_RS14750
uniprot id: C7MX76
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS19325
gene id: 471857:SVIR_RS19325
uniprot id: C7MS28
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

471857:SVIR RS12900
gene id: 471857:SVIR_RS12900
uniprot id: C7MUF6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS08110
gene id: 471857:SVIR_RS08110
uniprot id: C7MT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS17635
gene id: 471857:SVIR_RS17635
uniprot id: C7MQM9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS12420
gene id: 471857:SVIR_RS12420
uniprot id: C7N004
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS17055
gene id: 471857:SVIR_RS17055
uniprot id: C7MQ22
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

471857:SVIR RS16010
gene id: 471857:SVIR_RS16010
uniprot id: C7MZL5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

471857:SVIR RS13745
gene id: 471857:SVIR_RS13745
uniprot id: C7MVG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS15230
gene id: 471857:SVIR_RS15230
uniprot id: C7MY13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS16810
gene id: 471857:SVIR_RS16810
uniprot id: C7N0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS18675
gene id: 471857:SVIR_RS18675
uniprot id: C7MRG9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471857:SVIR RS17905
gene id: 471857:SVIR_RS17905
uniprot id: C7MR23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

471857:SVIR RS05405
gene id: 471857:SVIR_RS05405
uniprot id: C7MZ44
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

471857:SVIR RS03765
gene id: 471857:SVIR_RS03765
uniprot id: C7MWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

471857:SVIR RS11265
gene id: 471857:SVIR_RS11265
uniprot id: C7MXN8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

471857:SVIR RS02960
gene id: 471857:SVIR_RS02960
uniprot id: C7MUW2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

471857:SVIR RS19450
gene id: 471857:SVIR_RS19450
uniprot id: C7MS52
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

471857:SVIR RS17165
gene id: 471857:SVIR_RS17165
uniprot id: C7MQ43
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

471857:SVIR RS06995
gene id: 471857:SVIR_RS06995
uniprot id: C7MQT3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

471857:SVIR RS01680
gene id: 471857:SVIR_RS01680
uniprot id: C7MTF2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

471857:SVIR RS11940
gene id: 471857:SVIR_RS11940
uniprot id: C7MZ74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS07785
gene id: 471857:SVIR_RS07785
uniprot id: C7MSN6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

471857:SVIR RS07825
gene id: 471857:SVIR_RS07825
uniprot id: C7MSP4
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS13015
gene id: 471857:SVIR_RS13015
uniprot id: C7MUH5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

471857:SVIR RS04775
gene id: 471857:SVIR_RS04775
uniprot id: C7MY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

471857:SVIR RS18440
gene id: 471857:SVIR_RS18440
uniprot id: C7MRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

471857:SVIR RS14280
gene id: 471857:SVIR_RS14280
uniprot id: C7MWD3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

471857:SVIR RS02310
gene id: 471857:SVIR_RS02310
uniprot id: C7MU17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS18655
gene id: 471857:SVIR_RS18655
uniprot id: C7MRG5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS10735
gene id: 471857:SVIR_RS10735
uniprot id: C7MWV6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

471857:SVIR RS06255
gene id: 471857:SVIR_RS06255
uniprot id: C7MPT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

471857:SVIR RS11350
gene id: 471857:SVIR_RS11350
uniprot id: C7MXQ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

471857:SVIR RS00875
gene id: 471857:SVIR_RS00875
uniprot id: C7MSF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

471857:SVIR RS02235
gene id: 471857:SVIR_RS02235
uniprot id: C7MU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

471857:SVIR RS06355
gene id: 471857:SVIR_RS06355
uniprot id: C7MPV4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

471857:SVIR RS06645
gene id: 471857:SVIR_RS06645
uniprot id: C7MQA8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS09435
gene id: 471857:SVIR_RS09435
uniprot id: C7MV03
names: Similarity
messages: Belongs to the YciI family.

471857:SVIR RS14000
gene id: 471857:SVIR_RS14000
uniprot id: C7MW78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS01015
gene id: 471857:SVIR_RS01015
uniprot id: C7MSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS08695
gene id: 471857:SVIR_RS08695
uniprot id: C7MTS8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS02475
gene id: 471857:SVIR_RS02475
uniprot id: C7MU50
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS03135
gene id: 471857:SVIR_RS03135
uniprot id: C7MVJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471857:SVIR RS16525
gene id: 471857:SVIR_RS16525
uniprot id: C7N0D8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

471857:SVIR RS13775
gene id: 471857:SVIR_RS13775
uniprot id: C7MVH3
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS03385
gene id: 471857:SVIR_RS03385
uniprot id: C7MVP4
names: Similarity
messages: Belongs to the fructosamine kinase family.

471857:SVIR RS14370
gene id: 471857:SVIR_RS14370
uniprot id: C7MX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS00320
gene id: 471857:SVIR_RS00320
uniprot id: C7MRU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS00375
gene id: 471857:SVIR_RS00375
uniprot id: C7MRV3
names: Subcellular Location Annotation
messages: Periplasm

471857:SVIR RS14385
gene id: 471857:SVIR_RS14385
uniprot id: C7MX06
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS19610
gene id: 471857:SVIR_RS19610
uniprot id: C7MUB0
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

471857:SVIR RS16260
gene id: 471857:SVIR_RS16260
uniprot id: C7MZQ8
names: Similarity
messages: Belongs to the isochorismate synthase family.

471857:SVIR RS15660
gene id: 471857:SVIR_RS15660
uniprot id: C7MYT7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

471857:SVIR RS01785
gene id: 471857:SVIR_RS01785
uniprot id: C7MTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

471857:SVIR RS12510
gene id: 471857:SVIR_RS12510
uniprot id: C7N019
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

471857:SVIR RS09975
gene id: 471857:SVIR_RS09975
uniprot id: C7MVW3
names: Similarity
messages: Belongs to the ArsC family.

471857:SVIR RS02315
gene id: 471857:SVIR_RS02315
uniprot id: C7MU18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS02790
gene id: 471857:SVIR_RS02790
uniprot id: C7MUS7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

471857:SVIR RS07195
gene id: 471857:SVIR_RS07195
uniprot id: C7MQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS17880
gene id: 471857:SVIR_RS17880
uniprot id: C7MR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS01980
gene id: 471857:SVIR_RS01980
uniprot id: C7MTK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

471857:SVIR RS09345
gene id: 471857:SVIR_RS09345
uniprot id: C7MUY7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

471857:SVIR RS07680
gene id: 471857:SVIR_RS07680
uniprot id: C7MSL4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

471857:SVIR RS05385
gene id: 471857:SVIR_RS05385
uniprot id: C7MZ40
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS00950
gene id: 471857:SVIR_RS00950
uniprot id: C7MSR5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

471857:SVIR RS16975
gene id: 471857:SVIR_RS16975
uniprot id: C7MQ06
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS02250
gene id: 471857:SVIR_RS02250
uniprot id: C7MU05
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

471857:SVIR RS03990
gene id: 471857:SVIR_RS03990
uniprot id: C7MWM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

471857:SVIR RS07950
gene id: 471857:SVIR_RS07950
uniprot id: C7MT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

471857:SVIR RS13545
gene id: 471857:SVIR_RS13545
uniprot id: C7MVC6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

471857:SVIR RS05735
gene id: 471857:SVIR_RS05735
uniprot id: C7MZW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS13445
gene id: 471857:SVIR_RS13445
uniprot id: C7MVA6
names: Similarity
messages: Belongs to the peptidase S15 family.

471857:SVIR RS11445
gene id: 471857:SVIR_RS11445
uniprot id: C7MYD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

471857:SVIR RS11100
gene id: 471857:SVIR_RS11100
uniprot id: C7MXK5
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS00790
gene id: 471857:SVIR_RS00790
uniprot id: C7MSD5
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

471857:SVIR RS15520
gene id: 471857:SVIR_RS15520
uniprot id: C7MYQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

471857:SVIR RS07040
gene id: 471857:SVIR_RS07040
uniprot id: C7MQU2
names: Similarity
messages: Belongs to the CapA family.

471857:SVIR RS05885
gene id: 471857:SVIR_RS05885
uniprot id: C7MZY9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

471857:SVIR RS06455
gene id: 471857:SVIR_RS06455
uniprot id: C7MPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS03950
gene id: 471857:SVIR_RS03950
uniprot id: C7MWL2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

471857:SVIR RS16910
gene id: 471857:SVIR_RS16910
uniprot id: C7MPZ3
names: Similarity
messages: Belongs to the AAA ATPase family.

471857:SVIR RS13395
gene id: 471857:SVIR_RS13395
uniprot id: C7MV96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

471857:SVIR RS02075
gene id: 471857:SVIR_RS02075
uniprot id: C7MTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

471857:SVIR RS03635
gene id: 471857:SVIR_RS03635
uniprot id: C7MWF3
names: Similarity
messages: Belongs to the glutamine synthetase family.

471857:SVIR RS00975
gene id: 471857:SVIR_RS00975
uniprot id: C7MSS0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471857:SVIR RS13185
gene id: 471857:SVIR_RS13185
uniprot id: C7MUK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

471857:SVIR RS10880
gene id: 471857:SVIR_RS10880
uniprot id: C7MWY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS12635
gene id: 471857:SVIR_RS12635
uniprot id: C7N044
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS16140
gene id: 471857:SVIR_RS16140
uniprot id: C7MZN6
names: Similarity
messages: Belongs to the FGGY kinase family.

471857:SVIR RS15975
gene id: 471857:SVIR_RS15975
uniprot id: C7MZK7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

471857:SVIR RS16550
gene id: 471857:SVIR_RS16550
uniprot id: C7N0E3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS12330
gene id: 471857:SVIR_RS12330
uniprot id: C7MZF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

471857:SVIR RS10950
gene id: 471857:SVIR_RS10950
uniprot id: C7MXH5
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

471857:SVIR RS02625
gene id: 471857:SVIR_RS02625
uniprot id: C7MUP7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

471857:SVIR RS02240
gene id: 471857:SVIR_RS02240
uniprot id: C7MU03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS20140
gene id: 471857:SVIR_RS20140
uniprot id: C7MSR3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

471857:SVIR RS13035
gene id: 471857:SVIR_RS13035
uniprot id: C7MUH9
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS05910
gene id: 471857:SVIR_RS05910
uniprot id: C7MZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471857:SVIR RS12400
gene id: 471857:SVIR_RS12400
uniprot id: C7N000
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS06280
gene id: 471857:SVIR_RS06280
uniprot id: C7MPT9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

471857:SVIR RS18415
gene id: 471857:SVIR_RS18415
uniprot id: C7MRB7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

471857:SVIR RS17830
gene id: 471857:SVIR_RS17830
uniprot id: C7MQR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

471857:SVIR RS13010
gene id: 471857:SVIR_RS13010
uniprot id: C7MUH4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

471857:SVIR RS14615
gene id: 471857:SVIR_RS14615
uniprot id: C7MX52
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

471857:SVIR RS20335
gene id: 471857:SVIR_RS20335
uniprot id: C7MSG1
names: Similarity
messages: Belongs to the EspG family.

471857:SVIR RS04130
gene id: 471857:SVIR_RS04130
uniprot id: C7MXA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS01675
gene id: 471857:SVIR_RS01675
uniprot id: C7MTF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

471857:SVIR RS05260
gene id: 471857:SVIR_RS05260
uniprot id: C7MZ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS00450
gene id: 471857:SVIR_RS00450
uniprot id: C7MS67
names: Similarity
messages: Belongs to the CutA family.

471857:SVIR RS12495
gene id: 471857:SVIR_RS12495
uniprot id: C7N016
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

471857:SVIR RS15445
gene id: 471857:SVIR_RS15445
uniprot id: C7MYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

471857:SVIR RS17745
gene id: 471857:SVIR_RS17745
uniprot id: C7MQQ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

471857:SVIR RS15980
gene id: 471857:SVIR_RS15980
uniprot id: C7MZK8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

471857:SVIR RS00900
gene id: 471857:SVIR_RS00900
uniprot id: C7MSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS06510
gene id: 471857:SVIR_RS06510
uniprot id: C7MQ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

471857:SVIR RS01135
gene id: 471857:SVIR_RS01135
uniprot id: C7MSV1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

471857:SVIR RS18885
gene id: 471857:SVIR_RS18885
uniprot id: C7MRL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

471857:SVIR RS01570
gene id: 471857:SVIR_RS01570
uniprot id: C7MTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS18485
gene id: 471857:SVIR_RS18485
uniprot id: C7MRD1
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

471857:SVIR RS10965
gene id: 471857:SVIR_RS10965
uniprot id: C7MXH8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

471857:SVIR RS01255
gene id: 471857:SVIR_RS01255
uniprot id: C7MSX6
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

471857:SVIR RS08295
gene id: 471857:SVIR_RS08295
uniprot id: C7MT97
names: Similarity
messages: Belongs to the AHA1 family.

471857:SVIR RS05945
gene id: 471857:SVIR_RS05945
uniprot id: C7MPM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

471857:SVIR RS07570
gene id: 471857:SVIR_RS07570
uniprot id: C7MSJ2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

471857:SVIR RS16330
gene id: 471857:SVIR_RS16330
uniprot id: C7N099
names: Similarity
messages: Belongs to the TPP enzyme family.

471857:SVIR RS19420
gene id: 471857:SVIR_RS19420
uniprot id: C7MS46
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471857:SVIR RS03415
gene id: 471857:SVIR_RS03415
uniprot id: C7MVQ0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

471857:SVIR RS15715
gene id: 471857:SVIR_RS15715
uniprot id: C7MYU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS02015
gene id: 471857:SVIR_RS02015
uniprot id: C7MTV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

471857:SVIR RS01660
gene id: 471857:SVIR_RS01660
uniprot id: C7MTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS16935
gene id: 471857:SVIR_RS16935
uniprot id: C7MPZ8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

471857:SVIR RS00035
gene id: 471857:SVIR_RS00035
uniprot id: C7MRN9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

471857:SVIR RS18615
gene id: 471857:SVIR_RS18615
uniprot id: C7MRF7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

471857:SVIR RS05320
gene id: 471857:SVIR_RS05320
uniprot id: C7MZ26
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02420
gene id: 471857:SVIR_RS02420
uniprot id: C7MU39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

471857:SVIR RS09320
gene id: 471857:SVIR_RS09320
uniprot id: C7MUY2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

471857:SVIR RS09545
gene id: 471857:SVIR_RS09545
uniprot id: C7MV26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471857:SVIR RS15415
gene id: 471857:SVIR_RS15415
uniprot id: C7MYN7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS13710
gene id: 471857:SVIR_RS13710
uniprot id: C7MVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

471857:SVIR RS13940
gene id: 471857:SVIR_RS13940
uniprot id: C7MW67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS16720
gene id: 471857:SVIR_RS16720
uniprot id: C7N0H6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

471857:SVIR RS12800
gene id: 471857:SVIR_RS12800
uniprot id: C7N074
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471857:SVIR RS06715
gene id: 471857:SVIR_RS06715
uniprot id: C7MQC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

471857:SVIR RS15840
gene id: 471857:SVIR_RS15840
uniprot id: C7MZI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

471857:SVIR RS14845
gene id: 471857:SVIR_RS14845
uniprot id: C7MXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS18950
gene id: 471857:SVIR_RS18950
uniprot id: C7MRM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS06120
gene id: 471857:SVIR_RS06120
uniprot id: C7MPQ8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

471857:SVIR RS05185
gene id: 471857:SVIR_RS05185
uniprot id: C7MYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

471857:SVIR RS00030
gene id: 471857:SVIR_RS00030
uniprot id: C7MRN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

471857:SVIR RS02900
gene id: 471857:SVIR_RS02900
uniprot id: C7MUV0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

471857:SVIR RS16575
gene id: 471857:SVIR_RS16575
uniprot id: C7N0E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS17115
gene id: 471857:SVIR_RS17115
uniprot id: C7MQ34
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

471857:SVIR RS02265
gene id: 471857:SVIR_RS02265
uniprot id: C7MU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

471857:SVIR RS14830
gene id: 471857:SVIR_RS14830
uniprot id: C7MXT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS10960
gene id: 471857:SVIR_RS10960
uniprot id: C7MXH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471857:SVIR RS11205
gene id: 471857:SVIR_RS11205
uniprot id: C7MXM6
names: Subunit
messages: Monomer.

471857:SVIR RS19825
gene id: 471857:SVIR_RS19825
uniprot id: C7MY57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

471857:SVIR RS19380
gene id: 471857:SVIR_RS19380
uniprot id: C7MS39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

471857:SVIR RS12790
gene id: 471857:SVIR_RS12790
uniprot id: C7N072
names: Similarity
messages: Belongs to the ABC transporter superfamily.

471857:SVIR RS05500
gene id: 471857:SVIR_RS05500
uniprot id: C7MZ63
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

471857:SVIR RS00435
gene id: 471857:SVIR_RS00435
uniprot id: C7MS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471857:SVIR RS01800
gene id: 471857:SVIR_RS01800
uniprot id: C7MTH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

471857:SVIR RS13335
gene id: 471857:SVIR_RS13335
uniprot id: C7MV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

471857:SVIR RS13965
gene id: 471857:SVIR_RS13965
uniprot id: C7MW72
names: Similarity
messages: Belongs to the DEAD box helicase family.

471857:SVIR RS08020
gene id: 471857:SVIR_RS08020
uniprot id: C7MT43
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS04965
gene id: 471857:SVIR_RS04965
uniprot id: C7MYC8
names: Similarity
messages: Belongs to the UPF0047 family.

471857:SVIR RS03885
gene id: 471857:SVIR_RS03885
uniprot id: C7MWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

471857:SVIR RS19480
gene id: 471857:SVIR_RS19480
uniprot id: C7MS58
names: Similarity
messages: Belongs to the ParB family.

471857:SVIR RS17295
gene id: 471857:SVIR_RS17295
uniprot id: C7MQ67
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

471857:SVIR RS05680
gene id: 471857:SVIR_RS05680
uniprot id: C7MZV2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

471857:SVIR RS07740
gene id: 471857:SVIR_RS07740
uniprot id: C7MSM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471857:SVIR RS12615
gene id: 471857:SVIR_RS12615
uniprot id: C7N040
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS15570
gene id: 471857:SVIR_RS15570
uniprot id: C7MYR8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

471857:SVIR RS17035
gene id: 471857:SVIR_RS17035
uniprot id: C7MQ18
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

471857:SVIR RS04445
gene id: 471857:SVIR_RS04445
uniprot id: C7MY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

471857:SVIR RS08560
gene id: 471857:SVIR_RS08560
uniprot id: C7MTQ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

471857:SVIR RS05660
gene id: 471857:SVIR_RS05660
uniprot id: C7MZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS17895
gene id: 471857:SVIR_RS17895
uniprot id: C7MR21
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

471857:SVIR RS07190
gene id: 471857:SVIR_RS07190
uniprot id: C7MQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS10850
gene id: 471857:SVIR_RS10850
uniprot id: C7MWY0
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS02300
gene id: 471857:SVIR_RS02300
uniprot id: C7MU15
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

471857:SVIR RS11815
gene id: 471857:SVIR_RS11815
uniprot id: C7MYJ7
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS03330
gene id: 471857:SVIR_RS03330
uniprot id: C7MVN3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

471857:SVIR RS04670
gene id: 471857:SVIR_RS04670
uniprot id: C7MY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471857:SVIR RS16410
gene id: 471857:SVIR_RS16410
uniprot id: C7N0B5
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS00625
gene id: 471857:SVIR_RS00625
uniprot id: C7MSA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

471857:SVIR RS14240
gene id: 471857:SVIR_RS14240
uniprot id: C7MWC5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

471857:SVIR RS04485
gene id: 471857:SVIR_RS04485
uniprot id: C7MY31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

471857:SVIR RS00575
gene id: 471857:SVIR_RS00575
uniprot id: C7MS92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

471857:SVIR RS03575
gene id: 471857:SVIR_RS03575
uniprot id: C7MWE1
names: Similarity
messages: Belongs to the peptidase C40 family.

471857:SVIR RS01655
gene id: 471857:SVIR_RS01655
uniprot id: C7MTE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471857:SVIR RS12505
gene id: 471857:SVIR_RS12505
uniprot id: C7N018
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

471857:SVIR RS16930
gene id: 471857:SVIR_RS16930
uniprot id: C7MPZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

471857:SVIR RS01880
gene id: 471857:SVIR_RS01880
uniprot id: C7MTI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

471857:SVIR RS16925
gene id: 471857:SVIR_RS16925
uniprot id: C7MPZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

471857:SVIR RS03225
gene id: 471857:SVIR_RS03225
uniprot id: C7MVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

471857:SVIR RS04645
gene id: 471857:SVIR_RS04645
uniprot id: C7MY63
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

471857:SVIR RS18555
gene id: 471857:SVIR_RS18555
uniprot id: C7MRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

471857:SVIR RS13375
gene id: 471857:SVIR_RS13375
uniprot id: C7MV92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

471857:SVIR RS19500
gene id: 471857:SVIR_RS19500
uniprot id: C7MSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

471857:SVIR RS07895
gene id: 471857:SVIR_RS07895
uniprot id: C7MSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS16900
gene id: 471857:SVIR_RS16900
uniprot id: C7MPZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

471857:SVIR RS14675
gene id: 471857:SVIR_RS14675
uniprot id: C7MX63
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07180
gene id: 471857:SVIR_RS07180
uniprot id: C7MQX0
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS08830
gene id: 471857:SVIR_RS08830
uniprot id: C7MTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS13855
gene id: 471857:SVIR_RS13855
uniprot id: C7MW49
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

471857:SVIR RS07255
gene id: 471857:SVIR_RS07255
uniprot id: C7MQY1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS07525
gene id: 471857:SVIR_RS07525
uniprot id: C7MSI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

471857:SVIR RS12810
gene id: 471857:SVIR_RS12810
uniprot id: C7N076
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07150
gene id: 471857:SVIR_RS07150
uniprot id: C7MQW4
names: Similarity
messages: Belongs to the peptidase M16 family.

471857:SVIR RS18760
gene id: 471857:SVIR_RS18760
uniprot id: C7MRI6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471857:SVIR RS08630
gene id: 471857:SVIR_RS08630
uniprot id: C7MTR6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

471857:SVIR RS05950
gene id: 471857:SVIR_RS05950
uniprot id: C7MPM4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

471857:SVIR RS19255
gene id: 471857:SVIR_RS19255
uniprot id: C7MS14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS09615
gene id: 471857:SVIR_RS09615
uniprot id: C7MV40
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

471857:SVIR RS07185
gene id: 471857:SVIR_RS07185
uniprot id: C7MQX1
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04335
gene id: 471857:SVIR_RS04335
uniprot id: C7MXE2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

471857:SVIR RS18695
gene id: 471857:SVIR_RS18695
uniprot id: C7MRH3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

471857:SVIR RS14950
gene id: 471857:SVIR_RS14950
uniprot id: C7MXV7
names: Similarity
messages: Belongs to the peptidase S8 family.

471857:SVIR RS12670
gene id: 471857:SVIR_RS12670
uniprot id: C7N051
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

471857:SVIR RS17300
gene id: 471857:SVIR_RS17300
uniprot id: C7MQ68
names: Similarity
messages: Belongs to the Nth/MutY family.

471857:SVIR RS14005
gene id: 471857:SVIR_RS14005
uniprot id: C7MW79
names: Similarity
messages: Belongs to the LacAB/RpiB family.

471857:SVIR RS15735
gene id: 471857:SVIR_RS15735
uniprot id: C7MYV1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

471857:SVIR RS05195
gene id: 471857:SVIR_RS05195
uniprot id: C7MZ00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS03600
gene id: 471857:SVIR_RS03600
uniprot id: C7MWE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

471857:SVIR RS16555
gene id: 471857:SVIR_RS16555
uniprot id: C7N0E4
names: Similarity
messages: Belongs to the citrate synthase family.

471857:SVIR RS15155
gene id: 471857:SVIR_RS15155
uniprot id: C7MXZ8
names: Similarity
messages: Belongs to the UPF0434 family.

471857:SVIR RS01560
gene id: 471857:SVIR_RS01560
uniprot id: C7MTC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS06730
gene id: 471857:SVIR_RS06730
uniprot id: C7MQC5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

471857:SVIR RS07725
gene id: 471857:SVIR_RS07725
uniprot id: C7MSM4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

471857:SVIR RS07345
gene id: 471857:SVIR_RS07345
uniprot id: C7MQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

471857:SVIR RS06290
gene id: 471857:SVIR_RS06290
uniprot id: C7MPU1
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS02100
gene id: 471857:SVIR_RS02100
uniprot id: C7MTX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

471857:SVIR RS13675
gene id: 471857:SVIR_RS13675
uniprot id: C7MVF3
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

471857:SVIR RS11160
gene id: 471857:SVIR_RS11160
uniprot id: C7MXL7
names: Similarity
messages: Belongs to the universal stress protein A family.

471857:SVIR RS15100
gene id: 471857:SVIR_RS15100
uniprot id: C7MXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

471857:SVIR RS17045
gene id: 471857:SVIR_RS17045
uniprot id: C7MQ20
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

471857:SVIR RS14745
gene id: 471857:SVIR_RS14745
uniprot id: C7MX75
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

471857:SVIR RS07170
gene id: 471857:SVIR_RS07170
uniprot id: C7MQW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471857:SVIR RS03170
gene id: 471857:SVIR_RS03170
uniprot id: C7MVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

471857:SVIR RS07835
gene id: 471857:SVIR_RS07835
uniprot id: C7MSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

471857:SVIR RS14795
gene id: 471857:SVIR_RS14795
uniprot id: C7MXS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS11170
gene id: 471857:SVIR_RS11170
uniprot id: C7MXL9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

471857:SVIR RS12885
gene id: 471857:SVIR_RS12885
uniprot id: C7N093
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

471857:SVIR RS12525
gene id: 471857:SVIR_RS12525
uniprot id: C7N022
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

471857:SVIR RS08595
gene id: 471857:SVIR_RS08595
uniprot id: C7MTQ9
names: Similarity
messages: Belongs to the CobH/CbiC family.

471857:SVIR RS03090
gene id: 471857:SVIR_RS03090
uniprot id: C7MVI2
names: Similarity
messages: Belongs to the LOG family.

471857:SVIR RS04915
gene id: 471857:SVIR_RS04915
uniprot id: C7MYB7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

471857:SVIR RS00340
gene id: 471857:SVIR_RS00340
uniprot id: C7MRU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471857:SVIR RS14900
gene id: 471857:SVIR_RS14900
uniprot id: C7MXU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS12230
gene id: 471857:SVIR_RS12230
uniprot id: C7MZD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

471857:SVIR RS19125
gene id: 471857:SVIR_RS19125
uniprot id: C7MRY8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS05005
gene id: 471857:SVIR_RS05005
uniprot id: C7MYW3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

471857:SVIR RS02985
gene id: 471857:SVIR_RS02985
uniprot id: C7MUW7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

471857:SVIR RS19035
gene id: 471857:SVIR_RS19035
uniprot id: C7MRX0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

471857:SVIR RS00495
gene id: 471857:SVIR_RS00495
uniprot id: C7MS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

471857:SVIR RS13465
gene id: 471857:SVIR_RS13465
uniprot id: C7MVB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

471857:SVIR RS07135
gene id: 471857:SVIR_RS07135
uniprot id: C7MQW1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

471857:SVIR RS04655
gene id: 471857:SVIR_RS04655
uniprot id: C7MY65
names: Similarity
messages: Belongs to the acylphosphatase family.

471857:SVIR RS00805
gene id: 471857:SVIR_RS00805
uniprot id: C7MSD8
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

471857:SVIR RS07505
gene id: 471857:SVIR_RS07505
uniprot id: C7MSH9
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

471857:SVIR RS05370
gene id: 471857:SVIR_RS05370
uniprot id: C7MZ37
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

471857:SVIR RS07795
gene id: 471857:SVIR_RS07795
uniprot id: C7MSN8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

471857:SVIR RS16565
gene id: 471857:SVIR_RS16565
uniprot id: C7N0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

471857:SVIR RS18225
gene id: 471857:SVIR_RS18225
uniprot id: C7MR81
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

471857:SVIR RS04625
gene id: 471857:SVIR_RS04625
uniprot id: C7MY59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

471857:SVIR RS04185
gene id: 471857:SVIR_RS04185
uniprot id: C7MXB2
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS12380
gene id: 471857:SVIR_RS12380
uniprot id: C7MZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

471857:SVIR RS02095
gene id: 471857:SVIR_RS02095
uniprot id: C7MTX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

471857:SVIR RS16090
gene id: 471857:SVIR_RS16090
uniprot id: C7MZM7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS05460
gene id: 471857:SVIR_RS05460
uniprot id: C7MZ55
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

471857:SVIR RS05135
gene id: 471857:SVIR_RS05135
uniprot id: C7MYY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

471857:SVIR RS02050
gene id: 471857:SVIR_RS02050
uniprot id: C7MTW5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

471857:SVIR RS01545
gene id: 471857:SVIR_RS01545
uniprot id: C7MTC5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

471857:SVIR RS11575
gene id: 471857:SVIR_RS11575
uniprot id: C7MYF4
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS13325
gene id: 471857:SVIR_RS13325
uniprot id: C7MV82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

471857:SVIR RS19815
gene id: 471857:SVIR_RS19815
uniprot id: C7MWK2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

471857:SVIR RS19505
gene id: 471857:SVIR_RS19505
uniprot id: C7MSR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

471857:SVIR RS15945
gene id: 471857:SVIR_RS15945
uniprot id: C7MZK2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

471857:SVIR RS05900
gene id: 471857:SVIR_RS05900
uniprot id: C7MZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471857:SVIR RS02505
gene id: 471857:SVIR_RS02505
uniprot id: C7MU56
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

471857:SVIR RS11540
gene id: 471857:SVIR_RS11540
uniprot id: C7MYE9
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

471857:SVIR RS03905
gene id: 471857:SVIR_RS03905
uniprot id: C7MWK3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

471857:SVIR RS12390
gene id: 471857:SVIR_RS12390
uniprot id: C7MZG7
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS04435
gene id: 471857:SVIR_RS04435
uniprot id: C7MXG0
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

471857:SVIR RS12015
gene id: 471857:SVIR_RS12015
uniprot id: C7MZ89
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

471857:SVIR RS08770
gene id: 471857:SVIR_RS08770
uniprot id: C7MTU1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471857:SVIR RS04245
gene id: 471857:SVIR_RS04245
uniprot id: C7MXC4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

471857:SVIR RS05700
gene id: 471857:SVIR_RS05700
uniprot id: C7MZV6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS01620
gene id: 471857:SVIR_RS01620
uniprot id: C7MTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471857:SVIR RS07770
gene id: 471857:SVIR_RS07770
uniprot id: C7MSN3
names: Similarity
messages: Belongs to the GPI family.

471857:SVIR RS14620
gene id: 471857:SVIR_RS14620
uniprot id: C7MX53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

471857:SVIR RS17810
gene id: 471857:SVIR_RS17810
uniprot id: C7MQR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS01940
gene id: 471857:SVIR_RS01940
uniprot id: C7MTK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

471857:SVIR RS12080
gene id: 471857:SVIR_RS12080
uniprot id: C7MZA4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

471857:SVIR RS06125
gene id: 471857:SVIR_RS06125
uniprot id: C7MPQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

471857:SVIR RS12500
gene id: 471857:SVIR_RS12500
uniprot id: C7N017
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

471857:SVIR RS08240
gene id: 471857:SVIR_RS08240
uniprot id: C7MT87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

471857:SVIR RS05970
gene id: 471857:SVIR_RS05970
uniprot id: C7MPM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

471857:SVIR RS09950
gene id: 471857:SVIR_RS09950
uniprot id: C7MVV9
names: Similarity
messages: Belongs to the Fur family.

471857:SVIR RS14835
gene id: 471857:SVIR_RS14835
uniprot id: C7MXT3
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS07585
gene id: 471857:SVIR_RS07585
uniprot id: C7MSJ5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

471857:SVIR RS19385
gene id: 471857:SVIR_RS19385
uniprot id: C7MS40
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

471857:SVIR RS07865
gene id: 471857:SVIR_RS07865
uniprot id: C7MSQ2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

471857:SVIR RS06345
gene id: 471857:SVIR_RS06345
uniprot id: C7MPV2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471857:SVIR RS12245
gene id: 471857:SVIR_RS12245
uniprot id: C7MZD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

471857:SVIR RS01610
gene id: 471857:SVIR_RS01610
uniprot id: C7MTD8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS13725
gene id: 471857:SVIR_RS13725
uniprot id: C7MVG3
names: Similarity
messages: Belongs to the TrpC family.

471857:SVIR RS02070
gene id: 471857:SVIR_RS02070
uniprot id: C7MTW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

471857:SVIR RS13715
gene id: 471857:SVIR_RS13715
uniprot id: C7MVG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

471857:SVIR RS11120
gene id: 471857:SVIR_RS11120
uniprot id: C7MXK9
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS16385
gene id: 471857:SVIR_RS16385
uniprot id: C7N0B0
names: Similarity
messages: Belongs to the cytochrome P450 family.

471857:SVIR RS17990
gene id: 471857:SVIR_RS17990
uniprot id: C7MR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

471857:SVIR RS07695
gene id: 471857:SVIR_RS07695
uniprot id: C7MSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

471857:SVIR RS03670
gene id: 471857:SVIR_RS03670
uniprot id: C7MWF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

471857:SVIR RS14840
gene id: 471857:SVIR_RS14840
uniprot id: C7MXT4
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS15865
gene id: 471857:SVIR_RS15865
uniprot id: C7MZI6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

471857:SVIR RS17580
gene id: 471857:SVIR_RS17580
uniprot id: C7MQL8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS13280
gene id: 471857:SVIR_RS13280
uniprot id: C7MV74
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

471857:SVIR RS09640
gene id: 471857:SVIR_RS09640
uniprot id: C7MV45
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS09945
gene id: 471857:SVIR_RS09945
uniprot id: C7MVV8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

471857:SVIR RS03165
gene id: 471857:SVIR_RS03165
uniprot id: C7MVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

471857:SVIR RS17670
gene id: 471857:SVIR_RS17670
uniprot id: C7MQN6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS19350
gene id: 471857:SVIR_RS19350
uniprot id: C7MS33
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

471857:SVIR RS11995
gene id: 471857:SVIR_RS11995
uniprot id: C7MZ85
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

471857:SVIR RS04675
gene id: 471857:SVIR_RS04675
uniprot id: C7MY69
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

471857:SVIR RS04790
gene id: 471857:SVIR_RS04790
uniprot id: C7MY92
names: Similarity
messages: Belongs to the UPF0102 family.

471857:SVIR RS09180
gene id: 471857:SVIR_RS09180
uniprot id: C7MUC6
names: Similarity
messages: Belongs to the GcvT family.

471857:SVIR RS02295
gene id: 471857:SVIR_RS02295
uniprot id: C7MU14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

471857:SVIR RS18125
gene id: 471857:SVIR_RS18125
uniprot id: C7MR64
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

471857:SVIR RS10480
gene id: 471857:SVIR_RS10480
uniprot id: C7MWQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

471857:SVIR RS04325
gene id: 471857:SVIR_RS04325
uniprot id: C7MXE0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS07455
gene id: 471857:SVIR_RS07455
uniprot id: C7MSG9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471857:SVIR RS11460
gene id: 471857:SVIR_RS11460
uniprot id: C7MYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471857:SVIR RS01960
gene id: 471857:SVIR_RS01960
uniprot id: C7MTK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

471857:SVIR RS19355
gene id: 471857:SVIR_RS19355
uniprot id: C7MS34
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

471857:SVIR RS12470
gene id: 471857:SVIR_RS12470
uniprot id: C7N011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

471857:SVIR RS01205
gene id: 471857:SVIR_RS01205
uniprot id: C7MSW6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS14665
gene id: 471857:SVIR_RS14665
uniprot id: C7MX62
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS18560
gene id: 471857:SVIR_RS18560
uniprot id: C7MRE6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

471857:SVIR RS04830
gene id: 471857:SVIR_RS04830
uniprot id: C7MYA0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471857:SVIR RS10415
gene id: 471857:SVIR_RS10415
uniprot id: C7MWP6
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS16440
gene id: 471857:SVIR_RS16440
uniprot id: C7N0C1
names: Similarity
messages: Belongs to the TPP enzyme family.

471857:SVIR RS15590
gene id: 471857:SVIR_RS15590
uniprot id: C7MYS3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

471857:SVIR RS05595
gene id: 471857:SVIR_RS05595
uniprot id: C7MZT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

471857:SVIR RS08050
gene id: 471857:SVIR_RS08050
uniprot id: C7MT49
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471857:SVIR RS10975
gene id: 471857:SVIR_RS10975
uniprot id: C7MXI0
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS08125
gene id: 471857:SVIR_RS08125
uniprot id: C7MT64
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

471857:SVIR RS15565
gene id: 471857:SVIR_RS15565
uniprot id: C7MYR7
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

471857:SVIR RS05815
gene id: 471857:SVIR_RS05815
uniprot id: C7MZX7
names: Similarity
messages: Belongs to the FPG family.

471857:SVIR RS15710
gene id: 471857:SVIR_RS15710
uniprot id: C7MYU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

471857:SVIR RS03920
gene id: 471857:SVIR_RS03920
uniprot id: C7MWK6
names: Similarity
messages: Belongs to the HupF/HypC family.

471857:SVIR RS10720
gene id: 471857:SVIR_RS10720
uniprot id: C7MWV3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

471857:SVIR RS03200
gene id: 471857:SVIR_RS03200
uniprot id: C7MVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

471857:SVIR RS07395
gene id: 471857:SVIR_RS07395
uniprot id: C7MR09
names: Similarity
messages: Belongs to the TPP enzyme family.

471857:SVIR RS05630
gene id: 471857:SVIR_RS05630
uniprot id: C7MZU2
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS06655
gene id: 471857:SVIR_RS06655
uniprot id: C7MQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

471857:SVIR RS04320
gene id: 471857:SVIR_RS04320
uniprot id: C7MXD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

471857:SVIR RS07685
gene id: 471857:SVIR_RS07685
uniprot id: C7MSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

471857:SVIR RS17455
gene id: 471857:SVIR_RS17455
uniprot id: C7MQJ3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

471857:SVIR RS02460
gene id: 471857:SVIR_RS02460
uniprot id: C7MU47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

471857:SVIR RS03675
gene id: 471857:SVIR_RS03675
uniprot id: C7MWF8
names: Subcellular Location Annotation
messages: Membrane

471857:SVIR RS14810
gene id: 471857:SVIR_RS14810
uniprot id: C7MXS8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

471857:SVIR RS15160
gene id: 471857:SVIR_RS15160
uniprot id: C7MXZ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

471857:SVIR RS08450
gene id: 471857:SVIR_RS08450
uniprot id: C7MTN1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

471857:SVIR RS05255
gene id: 471857:SVIR_RS05255
uniprot id: C7MZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

471857:SVIR RS10700
gene id: 471857:SVIR_RS10700
uniprot id: C7MWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.