471854:DFER RS20685
gene id: 471854:DFER_RS20685
uniprot id: C6W034
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

471854:DFER RS05640
gene id: 471854:DFER_RS05640
uniprot id: C6W532
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS10995
gene id: 471854:DFER_RS10995
uniprot id: C6VYV0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS09675
gene id: 471854:DFER_RS09675
uniprot id: C6VW56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

471854:DFER RS19335
gene id: 471854:DFER_RS19335
uniprot id: C6VXQ8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

471854:DFER RS24860
gene id: 471854:DFER_RS24860
uniprot id: C6W7J6
names: Similarity
messages: Belongs to the universal stress protein A family.

471854:DFER RS12915
gene id: 471854:DFER_RS12915
uniprot id: C6W2H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

471854:DFER RS18915
gene id: 471854:DFER_RS18915
uniprot id: C6VWH9
names: Similarity
messages: Belongs to the threonine synthase family.

471854:DFER RS12815
gene id: 471854:DFER_RS12815
uniprot id: C6W2F8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

471854:DFER RS00315
gene id: 471854:DFER_RS00315
uniprot id: C6VUM6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

471854:DFER RS01855
gene id: 471854:DFER_RS01855
uniprot id: C6VYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

471854:DFER RS08935
gene id: 471854:DFER_RS08935
uniprot id: C6VUR4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS13310
gene id: 471854:DFER_RS13310
uniprot id: C6W2Q5
names: Similarity
messages: Belongs to the nitroreductase family.

471854:DFER RS12640
gene id: 471854:DFER_RS12640
uniprot id: C6W1P8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS23940
gene id: 471854:DFER_RS23940
uniprot id: C6W5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS13850
gene id: 471854:DFER_RS13850
uniprot id: C6W4B5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28830
gene id: 471854:DFER_RS28830
uniprot id: C6VY65
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

471854:DFER RS02245
gene id: 471854:DFER_RS02245
uniprot id: C6VZB2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

471854:DFER RS16275
gene id: 471854:DFER_RS16275
uniprot id: C6VRX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

471854:DFER RS27195
gene id: 471854:DFER_RS27195
uniprot id: C6VUG4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS14160
gene id: 471854:DFER_RS14160
uniprot id: C6W4H9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS04905
gene id: 471854:DFER_RS04905
uniprot id: C6W408
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS12705
gene id: 471854:DFER_RS12705
uniprot id: C6W1R0
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

471854:DFER RS05155
gene id: 471854:DFER_RS05155
uniprot id: C6W459
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS09170
gene id: 471854:DFER_RS09170
uniprot id: C6VUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS02865
gene id: 471854:DFER_RS02865
uniprot id: C6W0A9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS10870
gene id: 471854:DFER_RS10870
uniprot id: C6VYS5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS26630
gene id: 471854:DFER_RS26630
uniprot id: C6VU51
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

471854:DFER RS21685
gene id: 471854:DFER_RS21685
uniprot id: C6W1X8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

471854:DFER RS19825
gene id: 471854:DFER_RS19825
uniprot id: C6VYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS21640
gene id: 471854:DFER_RS21640
uniprot id: C6W1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

471854:DFER RS15555
gene id: 471854:DFER_RS15555
uniprot id: C6W6L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

471854:DFER RS11565
gene id: 471854:DFER_RS11565
uniprot id: C6VZT9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

471854:DFER RS16755
gene id: 471854:DFER_RS16755
uniprot id: C6VSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

471854:DFER RS15370
gene id: 471854:DFER_RS15370
uniprot id: C6W6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

471854:DFER RS15600
gene id: 471854:DFER_RS15600
uniprot id: C6W786
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

471854:DFER RS14845
gene id: 471854:DFER_RS14845
uniprot id: C6W5K1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

471854:DFER RS03010
gene id: 471854:DFER_RS03010
uniprot id: C6W0D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

471854:DFER RS24975
gene id: 471854:DFER_RS24975
uniprot id: C6W7M0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

471854:DFER RS05150
gene id: 471854:DFER_RS05150
uniprot id: C6W458
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

471854:DFER RS14215
gene id: 471854:DFER_RS14215
uniprot id: C6W4J0
names: Similarity
messages: Belongs to the peptidase M24B family.

471854:DFER RS13415
gene id: 471854:DFER_RS13415
uniprot id: C6W3F1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS17525
gene id: 471854:DFER_RS17525
uniprot id: C6VTX3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17895
gene id: 471854:DFER_RS17895
uniprot id: C6VU46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

471854:DFER RS02225
gene id: 471854:DFER_RS02225
uniprot id: C6VZA8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS25905
gene id: 471854:DFER_RS25905
uniprot id: C6VSG2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

471854:DFER RS28470
gene id: 471854:DFER_RS28470
uniprot id: C6VXZ2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS24245
gene id: 471854:DFER_RS24245
uniprot id: C6W5X8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS23435
gene id: 471854:DFER_RS23435
uniprot id: C6W4T3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS14790
gene id: 471854:DFER_RS14790
uniprot id: C6W5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

471854:DFER RS21145
gene id: 471854:DFER_RS21145
uniprot id: C6W0Z1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

471854:DFER RS08000
gene id: 471854:DFER_RS08000
uniprot id: C6VSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS27645
gene id: 471854:DFER_RS27645
uniprot id: C6VVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

471854:DFER RS21285
gene id: 471854:DFER_RS21285
uniprot id: C6W118
names: Similarity
messages: Belongs to the DapA family.

471854:DFER RS12555
gene id: 471854:DFER_RS12555
uniprot id: C6W1N1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

471854:DFER RS12135
gene id: 471854:DFER_RS12135
uniprot id: C6W0S1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

471854:DFER RS15235
gene id: 471854:DFER_RS15235
uniprot id: C6W6F5
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

471854:DFER RS23420
gene id: 471854:DFER_RS23420
uniprot id: C6W4T0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS20440
gene id: 471854:DFER_RS20440
uniprot id: C6VZY4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS23965
gene id: 471854:DFER_RS23965
uniprot id: C6W5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

471854:DFER RS00435
gene id: 471854:DFER_RS00435
uniprot id: C6VVQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS23760
gene id: 471854:DFER_RS23760
uniprot id: C6W5N1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

471854:DFER RS27770
gene id: 471854:DFER_RS27770
uniprot id: C6VVM2
names: Similarity
messages: Belongs to the SCO1/2 family.

471854:DFER RS23575
gene id: 471854:DFER_RS23575
uniprot id: C6W4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

471854:DFER RS05010
gene id: 471854:DFER_RS05010
uniprot id: C6W429
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS20095
gene id: 471854:DFER_RS20095
uniprot id: C6VZ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS15180
gene id: 471854:DFER_RS15180
uniprot id: C6W6E4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

471854:DFER RS06410
gene id: 471854:DFER_RS06410
uniprot id: C6W666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

471854:DFER RS21760
gene id: 471854:DFER_RS21760
uniprot id: C6W1Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

471854:DFER RS12270
gene id: 471854:DFER_RS12270
uniprot id: C6W1H4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS20495
gene id: 471854:DFER_RS20495
uniprot id: C6VZZ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

471854:DFER RS08775
gene id: 471854:DFER_RS08775
uniprot id: C6VTS6
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS12145
gene id: 471854:DFER_RS12145
uniprot id: C6W0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

471854:DFER RS06075
gene id: 471854:DFER_RS06075
uniprot id: C6W600
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

471854:DFER RS21125
gene id: 471854:DFER_RS21125
uniprot id: C6W0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

471854:DFER RS20660
gene id: 471854:DFER_RS20660
uniprot id: C6W028
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

471854:DFER RS18370
gene id: 471854:DFER_RS18370
uniprot id: C6VV85
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS06045
gene id: 471854:DFER_RS06045
uniprot id: C6W5Z4
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

471854:DFER RS03025
gene id: 471854:DFER_RS03025
uniprot id: C6W0E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

471854:DFER RS06040
gene id: 471854:DFER_RS06040
uniprot id: C6W5Z3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

471854:DFER RS04985
gene id: 471854:DFER_RS04985
uniprot id: C6W424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS28055
gene id: 471854:DFER_RS28055
uniprot id: C6VWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

471854:DFER RS28010
gene id: 471854:DFER_RS28010
uniprot id: C6VWQ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS30140
gene id: 471854:DFER_RS30140
uniprot id: C6W5D7
names: Similarity
messages: Belongs to the peptidase C40 family.

471854:DFER RS13575
gene id: 471854:DFER_RS13575
uniprot id: C6W3I3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS25700
gene id: 471854:DFER_RS25700
uniprot id: C6VSC1
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS22205
gene id: 471854:DFER_RS22205
uniprot id: C6W2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS28020
gene id: 471854:DFER_RS28020
uniprot id: C6VWQ2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS24030
gene id: 471854:DFER_RS24030
uniprot id: C6W5T5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28025
gene id: 471854:DFER_RS28025
uniprot id: C6VWQ3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS22100
gene id: 471854:DFER_RS22100
uniprot id: C6W2S3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

471854:DFER RS25520
gene id: 471854:DFER_RS25520
uniprot id: C6VS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

471854:DFER RS20160
gene id: 471854:DFER_RS20160
uniprot id: C6VZ49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

471854:DFER RS24135
gene id: 471854:DFER_RS24135
uniprot id: C6W5V6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS15835
gene id: 471854:DFER_RS15835
uniprot id: C6W7D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

471854:DFER RS17210
gene id: 471854:DFER_RS17210
uniprot id: C6VT36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

471854:DFER RS18455
gene id: 471854:DFER_RS18455
uniprot id: C6VVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

471854:DFER RS15295
gene id: 471854:DFER_RS15295
uniprot id: C6W6G7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS03095
gene id: 471854:DFER_RS03095
uniprot id: C6W0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS07445
gene id: 471854:DFER_RS07445
uniprot id: C6VRQ1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS03220
gene id: 471854:DFER_RS03220
uniprot id: C6W155
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS12285
gene id: 471854:DFER_RS12285
uniprot id: C6W1H7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

471854:DFER RS22350
gene id: 471854:DFER_RS22350
uniprot id: C6W2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

471854:DFER RS26800
gene id: 471854:DFER_RS26800
uniprot id: C6VU84
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

471854:DFER RS14920
gene id: 471854:DFER_RS14920
uniprot id: C6W5L5
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS08205
gene id: 471854:DFER_RS08205
uniprot id: C6VST4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

471854:DFER RS16190
gene id: 471854:DFER_RS16190
uniprot id: C6VRW1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

471854:DFER RS21525
gene id: 471854:DFER_RS21525
uniprot id: C6W1U6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

471854:DFER RS06625
gene id: 471854:DFER_RS06625
uniprot id: C6W6Y2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS19290
gene id: 471854:DFER_RS19290
uniprot id: C6VXP8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

471854:DFER RS21740
gene id: 471854:DFER_RS21740
uniprot id: C6W1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

471854:DFER RS10380
gene id: 471854:DFER_RS10380
uniprot id: C6VXI8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

471854:DFER RS14100
gene id: 471854:DFER_RS14100
uniprot id: C6W4G7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

471854:DFER RS24100
gene id: 471854:DFER_RS24100
uniprot id: C6W5U9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS19775
gene id: 471854:DFER_RS19775
uniprot id: C6VYX3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

471854:DFER RS25495
gene id: 471854:DFER_RS25495
uniprot id: C6VS82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

471854:DFER RS28210
gene id: 471854:DFER_RS28210
uniprot id: C6VWU2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

471854:DFER RS24060
gene id: 471854:DFER_RS24060
uniprot id: C6W5U1
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

471854:DFER RS18715
gene id: 471854:DFER_RS18715
uniprot id: C6VWE2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

471854:DFER RS23625
gene id: 471854:DFER_RS23625
uniprot id: C6W4X0
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

471854:DFER RS19300
gene id: 471854:DFER_RS19300
uniprot id: C6VXQ0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

471854:DFER RS00050
gene id: 471854:DFER_RS00050
uniprot id: C6VUH3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

471854:DFER RS23655
gene id: 471854:DFER_RS23655
uniprot id: C6W4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS17185
gene id: 471854:DFER_RS17185
uniprot id: C6VT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS23490
gene id: 471854:DFER_RS23490
uniprot id: C6W4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS17975
gene id: 471854:DFER_RS17975
uniprot id: C6VV07
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS12205
gene id: 471854:DFER_RS12205
uniprot id: C6W0T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS14305
gene id: 471854:DFER_RS14305
uniprot id: C6W4K9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

471854:DFER RS21610
gene id: 471854:DFER_RS21610
uniprot id: C6W1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

471854:DFER RS08075
gene id: 471854:DFER_RS08075
uniprot id: C6VSQ8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS10430
gene id: 471854:DFER_RS10430
uniprot id: C6VXJ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS20595
gene id: 471854:DFER_RS20595
uniprot id: C6W015
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

471854:DFER RS02300
gene id: 471854:DFER_RS02300
uniprot id: C6VZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

471854:DFER RS03710
gene id: 471854:DFER_RS03710
uniprot id: C6W1F3
names: Similarity
messages: Belongs to the RutC family.

471854:DFER RS12715
gene id: 471854:DFER_RS12715
uniprot id: C6W1R2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

471854:DFER RS06945
gene id: 471854:DFER_RS06945
uniprot id: C6W746
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

471854:DFER RS09935
gene id: 471854:DFER_RS09935
uniprot id: C6VX99
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS09690
gene id: 471854:DFER_RS09690
uniprot id: C6VW60
names: Similarity
messages: Belongs to the peptidase S9C family.

471854:DFER RS08505
gene id: 471854:DFER_RS08505
uniprot id: C6VTM2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS07250
gene id: 471854:DFER_RS07250
uniprot id: C6VRL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471854:DFER RS18575
gene id: 471854:DFER_RS18575
uniprot id: C6VWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

471854:DFER RS23795
gene id: 471854:DFER_RS23795
uniprot id: C6W5N8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

471854:DFER RS21655
gene id: 471854:DFER_RS21655
uniprot id: C6W1X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

471854:DFER RS19605
gene id: 471854:DFER_RS19605
uniprot id: C6VXW2
names: Similarity
messages: Belongs to the SUI1 family.

471854:DFER RS21110
gene id: 471854:DFER_RS21110
uniprot id: C6W0Y4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

471854:DFER RS20530
gene id: 471854:DFER_RS20530
uniprot id: C6W002
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

471854:DFER RS24565
gene id: 471854:DFER_RS24565
uniprot id: C6W6R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

471854:DFER RS15265
gene id: 471854:DFER_RS15265
uniprot id: C6W6G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

471854:DFER RS12440
gene id: 471854:DFER_RS12440
uniprot id: C6W1K8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS22860
gene id: 471854:DFER_RS22860
uniprot id: C6W3U1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

471854:DFER RS24775
gene id: 471854:DFER_RS24775
uniprot id: C6W6W2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

471854:DFER RS19380
gene id: 471854:DFER_RS19380
uniprot id: C6VXR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS15050
gene id: 471854:DFER_RS15050
uniprot id: C6W6B8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

471854:DFER RS00405
gene id: 471854:DFER_RS00405
uniprot id: C6VVP8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

471854:DFER RS28825
gene id: 471854:DFER_RS28825
uniprot id: C6VY64
names: Similarity
messages: Belongs to the arginine deiminase family.

471854:DFER RS11915
gene id: 471854:DFER_RS11915
uniprot id: C6W0M7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

471854:DFER RS28760
gene id: 471854:DFER_RS28760
uniprot id: C6VY51
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

471854:DFER RS02215
gene id: 471854:DFER_RS02215
uniprot id: C6VZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

471854:DFER RS20125
gene id: 471854:DFER_RS20125
uniprot id: C6VZ41
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

471854:DFER RS18255
gene id: 471854:DFER_RS18255
uniprot id: C6VV63
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

471854:DFER RS08770
gene id: 471854:DFER_RS08770
uniprot id: C6VTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS16900
gene id: 471854:DFER_RS16900
uniprot id: C6VSY0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471854:DFER RS01045
gene id: 471854:DFER_RS01045
uniprot id: C6VX12
names: Similarity
messages: Belongs to the DprA/Smf family.

471854:DFER RS03550
gene id: 471854:DFER_RS03550
uniprot id: C6W1C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS07240
gene id: 471854:DFER_RS07240
uniprot id: C6VRL2
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS01615
gene id: 471854:DFER_RS01615
uniprot id: C6VYB8
names: Similarity
messages: Belongs to the Dps family.

471854:DFER RS22550
gene id: 471854:DFER_RS22550
uniprot id: C6W316
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

471854:DFER RS10025
gene id: 471854:DFER_RS10025
uniprot id: C6VXB7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

471854:DFER RS13125
gene id: 471854:DFER_RS13125
uniprot id: C6W2M0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

471854:DFER RS05685
gene id: 471854:DFER_RS05685
uniprot id: C6W542
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS18855
gene id: 471854:DFER_RS18855
uniprot id: C6VWG7
names: Similarity
messages: Belongs to the TrpF family.

471854:DFER RS02110
gene id: 471854:DFER_RS02110
uniprot id: C6VZ85
names: Similarity
messages: Belongs to the thioredoxin family.

471854:DFER RS28605
gene id: 471854:DFER_RS28605
uniprot id: C6VY20
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

471854:DFER RS23300
gene id: 471854:DFER_RS23300
uniprot id: C6W4Q6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06160
gene id: 471854:DFER_RS06160
uniprot id: C6W616
names: Similarity
messages: Belongs to the ribF family.

471854:DFER RS18845
gene id: 471854:DFER_RS18845
uniprot id: C6VWG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS08360
gene id: 471854:DFER_RS08360
uniprot id: C6VTJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

471854:DFER RS06825
gene id: 471854:DFER_RS06825
uniprot id: C6W721
names: Similarity
messages: Belongs to the alkaline phosphatase family.

471854:DFER RS25820
gene id: 471854:DFER_RS25820
uniprot id: C6VSE6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS00320
gene id: 471854:DFER_RS00320
uniprot id: C6VUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS25920
gene id: 471854:DFER_RS25920
uniprot id: C6VSG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS10905
gene id: 471854:DFER_RS10905
uniprot id: C6VYT2
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

471854:DFER RS29055
gene id: 471854:DFER_RS29055
uniprot id: C6W268
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

471854:DFER RS00205
gene id: 471854:DFER_RS00205
uniprot id: C6VUK4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS24945
gene id: 471854:DFER_RS24945
uniprot id: C6W7L4
names: Similarity
messages: Belongs to the glutamate synthase family.

471854:DFER RS13955
gene id: 471854:DFER_RS13955
uniprot id: C6W4D8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS07900
gene id: 471854:DFER_RS07900
uniprot id: C6VSM3
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS13440
gene id: 471854:DFER_RS13440
uniprot id: C6W3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS24375
gene id: 471854:DFER_RS24375
uniprot id: C6W6N2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

471854:DFER RS12740
gene id: 471854:DFER_RS12740
uniprot id: C6W1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

471854:DFER RS12780
gene id: 471854:DFER_RS12780
uniprot id: C6W1S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

471854:DFER RS25475
gene id: 471854:DFER_RS25475
uniprot id: C6VS78
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

471854:DFER RS12905
gene id: 471854:DFER_RS12905
uniprot id: C6W2H6
names: Similarity
messages: Belongs to the UPF0175 family.

471854:DFER RS19330
gene id: 471854:DFER_RS19330
uniprot id: C6VXQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

471854:DFER RS17930
gene id: 471854:DFER_RS17930
uniprot id: C6VUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

471854:DFER RS13000
gene id: 471854:DFER_RS13000
uniprot id: C6W2J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

471854:DFER RS03100
gene id: 471854:DFER_RS03100
uniprot id: C6W0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS00745
gene id: 471854:DFER_RS00745
uniprot id: C6VVW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

471854:DFER RS28615
gene id: 471854:DFER_RS28615
uniprot id: C6VY22
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

471854:DFER RS02425
gene id: 471854:DFER_RS02425
uniprot id: C6VZE7
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS14205
gene id: 471854:DFER_RS14205
uniprot id: C6W4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

471854:DFER RS11700
gene id: 471854:DFER_RS11700
uniprot id: C6W0I3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

471854:DFER RS25130
gene id: 471854:DFER_RS25130
uniprot id: C6W7Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

471854:DFER RS11960
gene id: 471854:DFER_RS11960
uniprot id: C6W0N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

471854:DFER RS16220
gene id: 471854:DFER_RS16220
uniprot id: C6VRW7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

471854:DFER RS14295
gene id: 471854:DFER_RS14295
uniprot id: C6W4K7
names: Similarity
messages: Belongs to the UPF0162 family.

471854:DFER RS15830
gene id: 471854:DFER_RS15830
uniprot id: C6W7D2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

471854:DFER RS21855
gene id: 471854:DFER_RS21855
uniprot id: C6W214
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

471854:DFER RS17865
gene id: 471854:DFER_RS17865
uniprot id: C6VU40
names: Similarity
messages: Belongs to the GARS family.

471854:DFER RS24115
gene id: 471854:DFER_RS24115
uniprot id: C6W5V2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS05630
gene id: 471854:DFER_RS05630
uniprot id: C6W530
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

471854:DFER RS17190
gene id: 471854:DFER_RS17190
uniprot id: C6VT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS18635
gene id: 471854:DFER_RS18635
uniprot id: C6VWC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

471854:DFER RS28065
gene id: 471854:DFER_RS28065
uniprot id: C6VWR1
names: Similarity
messages: Belongs to the peptidase S13 family.

471854:DFER RS09230
gene id: 471854:DFER_RS09230
uniprot id: C6VUX0
names: Similarity
messages: Belongs to the peptidase S33 family.

471854:DFER RS10175
gene id: 471854:DFER_RS10175
uniprot id: C6VXE7
names: Similarity
messages: Belongs to the peptidase M1 family.

471854:DFER RS19475
gene id: 471854:DFER_RS19475
uniprot id: C6VXT6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

471854:DFER RS20330
gene id: 471854:DFER_RS20330
uniprot id: C6VZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS00165
gene id: 471854:DFER_RS00165
uniprot id: C6VUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

471854:DFER RS20510
gene id: 471854:DFER_RS20510
uniprot id: C6VZZ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS18205
gene id: 471854:DFER_RS18205
uniprot id: C6VV53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS25000
gene id: 471854:DFER_RS25000
uniprot id: C6W7M5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

471854:DFER RS25205
gene id: 471854:DFER_RS25205
uniprot id: C6W7R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

471854:DFER RS27455
gene id: 471854:DFER_RS27455
uniprot id: C6VVG1
names: Similarity
messages: Belongs to the MYG1 family.

471854:DFER RS17230
gene id: 471854:DFER_RS17230
uniprot id: C6VT40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

471854:DFER RS01100
gene id: 471854:DFER_RS01100
uniprot id: C6VX23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

471854:DFER RS10990
gene id: 471854:DFER_RS10990
uniprot id: C6VYU9
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS24845
gene id: 471854:DFER_RS24845
uniprot id: C6W7J3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

471854:DFER RS21650
gene id: 471854:DFER_RS21650
uniprot id: C6W1X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

471854:DFER RS20790
gene id: 471854:DFER_RS20790
uniprot id: C6W054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

471854:DFER RS24675
gene id: 471854:DFER_RS24675
uniprot id: C6W6U3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS23225
gene id: 471854:DFER_RS23225
uniprot id: C6W4P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

471854:DFER RS03035
gene id: 471854:DFER_RS03035
uniprot id: C6W0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS19515
gene id: 471854:DFER_RS19515
uniprot id: C6VXU4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS23355
gene id: 471854:DFER_RS23355
uniprot id: C6W4R7
names: Function
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

471854:DFER RS01040
gene id: 471854:DFER_RS01040
uniprot id: C6VX11
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

471854:DFER RS01035
gene id: 471854:DFER_RS01035
uniprot id: C6VX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

471854:DFER RS20930
gene id: 471854:DFER_RS20930
uniprot id: C6W0V1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

471854:DFER RS07390
gene id: 471854:DFER_RS07390
uniprot id: C6VRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS15490
gene id: 471854:DFER_RS15490
uniprot id: C6W6K3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS26260
gene id: 471854:DFER_RS26260
uniprot id: C6VT98
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

471854:DFER RS18895
gene id: 471854:DFER_RS18895
uniprot id: C6VWH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

471854:DFER RS00650
gene id: 471854:DFER_RS00650
uniprot id: C6VVU9
names: Similarity
messages: Belongs to the FPG family.

471854:DFER RS05100
gene id: 471854:DFER_RS05100
uniprot id: C6W448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS24650
gene id: 471854:DFER_RS24650
uniprot id: C6W6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS19805
gene id: 471854:DFER_RS19805
uniprot id: C6VYX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

471854:DFER RS09990
gene id: 471854:DFER_RS09990
uniprot id: C6VXB0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

471854:DFER RS12560
gene id: 471854:DFER_RS12560
uniprot id: C6W1N2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06785
gene id: 471854:DFER_RS06785
uniprot id: C6W713
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS19065
gene id: 471854:DFER_RS19065
uniprot id: C6VWK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

471854:DFER RS23325
gene id: 471854:DFER_RS23325
uniprot id: C6W4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

471854:DFER RS17580
gene id: 471854:DFER_RS17580
uniprot id: C6VTY4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS21830
gene id: 471854:DFER_RS21830
uniprot id: C6W209
names: Similarity
messages: Belongs to the NDK family.

471854:DFER RS25110
gene id: 471854:DFER_RS25110
uniprot id: C6W7P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

471854:DFER RS07550
gene id: 471854:DFER_RS07550
uniprot id: C6VRS4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

471854:DFER RS08885
gene id: 471854:DFER_RS08885
uniprot id: C6VUQ3
names: Similarity
messages: Belongs to the catalase family.

471854:DFER RS06140
gene id: 471854:DFER_RS06140
uniprot id: C6W612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

471854:DFER RS21795
gene id: 471854:DFER_RS21795
uniprot id: C6W202
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

471854:DFER RS05265
gene id: 471854:DFER_RS05265
uniprot id: C6W480
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

471854:DFER RS18795
gene id: 471854:DFER_RS18795
uniprot id: C6VWF8
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

471854:DFER RS10335
gene id: 471854:DFER_RS10335
uniprot id: C6VXH9
names: Similarity
messages: Belongs to the peptidase U62 family.

471854:DFER RS10800
gene id: 471854:DFER_RS10800
uniprot id: C6VYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS24585
gene id: 471854:DFER_RS24585
uniprot id: C6W6S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

471854:DFER RS03065
gene id: 471854:DFER_RS03065
uniprot id: C6W0E9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS19265
gene id: 471854:DFER_RS19265
uniprot id: C6VXP3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

471854:DFER RS20365
gene id: 471854:DFER_RS20365
uniprot id: C6VZW8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS15770
gene id: 471854:DFER_RS15770
uniprot id: C6W7C0
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

471854:DFER RS14145
gene id: 471854:DFER_RS14145
uniprot id: C6W4H6
names: Similarity
messages: Belongs to the DEAD box helicase family.

471854:DFER RS21645
gene id: 471854:DFER_RS21645
uniprot id: C6W1X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

471854:DFER RS09325
gene id: 471854:DFER_RS09325
uniprot id: C6VUY9
names: Similarity
messages: Belongs to the RutC family.

471854:DFER RS24605
gene id: 471854:DFER_RS24605
uniprot id: C6W6S8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

471854:DFER RS17450
gene id: 471854:DFER_RS17450
uniprot id: C6VTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS08285
gene id: 471854:DFER_RS08285
uniprot id: C6VTH9
names: Similarity
messages: Belongs to the manganese catalase family.

471854:DFER RS22075
gene id: 471854:DFER_RS22075
uniprot id: C6W2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

471854:DFER RS15240
gene id: 471854:DFER_RS15240
uniprot id: C6W6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

471854:DFER RS06765
gene id: 471854:DFER_RS06765
uniprot id: C6W709
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

471854:DFER RS25645
gene id: 471854:DFER_RS25645
uniprot id: C6VSB2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

471854:DFER RS16750
gene id: 471854:DFER_RS16750
uniprot id: C6VSU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

471854:DFER RS28225
gene id: 471854:DFER_RS28225
uniprot id: C6VWU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471854:DFER RS03990
gene id: 471854:DFER_RS03990
uniprot id: C6W294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS03260
gene id: 471854:DFER_RS03260
uniprot id: C6W163
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18415
gene id: 471854:DFER_RS18415
uniprot id: C6VV94
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

471854:DFER RS21930
gene id: 471854:DFER_RS21930
uniprot id: C6W228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS21690
gene id: 471854:DFER_RS21690
uniprot id: C6W1X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

471854:DFER RS14345
gene id: 471854:DFER_RS14345
uniprot id: C6W4L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS21865
gene id: 471854:DFER_RS21865
uniprot id: C6W216
names: Similarity
messages: Belongs to the Skp family.

471854:DFER RS17150
gene id: 471854:DFER_RS17150
uniprot id: C6VT24
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS14230
gene id: 471854:DFER_RS14230
uniprot id: C6W4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

471854:DFER RS17855
gene id: 471854:DFER_RS17855
uniprot id: C6VU38
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

471854:DFER RS05310
gene id: 471854:DFER_RS05310
uniprot id: C6W489
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

471854:DFER RS22145
gene id: 471854:DFER_RS22145
uniprot id: C6W2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

471854:DFER RS18955
gene id: 471854:DFER_RS18955
uniprot id: C6VWI2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS20480
gene id: 471854:DFER_RS20480
uniprot id: C6VZZ2
names: Similarity
messages: Belongs to the LOG family.

471854:DFER RS14815
gene id: 471854:DFER_RS14815
uniprot id: C6W5J5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS22395
gene id: 471854:DFER_RS22395
uniprot id: C6W2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS12170
gene id: 471854:DFER_RS12170
uniprot id: C6W0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

471854:DFER RS09810
gene id: 471854:DFER_RS09810
uniprot id: C6VW84
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

471854:DFER RS21035
gene id: 471854:DFER_RS21035
uniprot id: C6W0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS12710
gene id: 471854:DFER_RS12710
uniprot id: C6W1R1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS02765
gene id: 471854:DFER_RS02765
uniprot id: C6W089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS10715
gene id: 471854:DFER_RS10715
uniprot id: C6VYP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS08630
gene id: 471854:DFER_RS08630
uniprot id: C6VTP7
names: Similarity
messages: Belongs to the YjdM family.

471854:DFER RS05970
gene id: 471854:DFER_RS05970
uniprot id: C6W599
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

471854:DFER RS02730
gene id: 471854:DFER_RS02730
uniprot id: C6W083
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS21510
gene id: 471854:DFER_RS21510
uniprot id: C6W1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

471854:DFER RS15845
gene id: 471854:DFER_RS15845
uniprot id: C6W7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

471854:DFER RS28435
gene id: 471854:DFER_RS28435
uniprot id: C6VXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS06385
gene id: 471854:DFER_RS06385
uniprot id: C6W661
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28325
gene id: 471854:DFER_RS28325
uniprot id: C6VWW5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS15195
gene id: 471854:DFER_RS15195
uniprot id: C6W6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS00660
gene id: 471854:DFER_RS00660
uniprot id: C6VVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

471854:DFER RS11955
gene id: 471854:DFER_RS11955
uniprot id: C6W0N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

471854:DFER RS14300
gene id: 471854:DFER_RS14300
uniprot id: C6W4K8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

471854:DFER RS25865
gene id: 471854:DFER_RS25865
uniprot id: C6VSF6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

471854:DFER RS10760
gene id: 471854:DFER_RS10760
uniprot id: C6VYQ4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS12880
gene id: 471854:DFER_RS12880
uniprot id: C6W2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS23075
gene id: 471854:DFER_RS23075
uniprot id: C6W3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

471854:DFER RS25595
gene id: 471854:DFER_RS25595
uniprot id: C6VSA2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS08750
gene id: 471854:DFER_RS08750
uniprot id: C6VTS2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS16135
gene id: 471854:DFER_RS16135
uniprot id: C6VRV2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

471854:DFER RS06855
gene id: 471854:DFER_RS06855
uniprot id: C6W727
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS19870
gene id: 471854:DFER_RS19870
uniprot id: C6VYZ3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

471854:DFER RS07750
gene id: 471854:DFER_RS07750
uniprot id: C6VSJ4
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS02740
gene id: 471854:DFER_RS02740
uniprot id: C6W085
names: Similarity
messages: Belongs to the citrate synthase family.

471854:DFER RS14565
gene id: 471854:DFER_RS14565
uniprot id: C6W5E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS10000
gene id: 471854:DFER_RS10000
uniprot id: C6VXB2
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

471854:DFER RS12850
gene id: 471854:DFER_RS12850
uniprot id: C6W2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS24400
gene id: 471854:DFER_RS24400
uniprot id: C6W6N7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS17635
gene id: 471854:DFER_RS17635
uniprot id: C6VTZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

471854:DFER RS16825
gene id: 471854:DFER_RS16825
uniprot id: C6VSW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS19350
gene id: 471854:DFER_RS19350
uniprot id: C6VXR1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

471854:DFER RS14275
gene id: 471854:DFER_RS14275
uniprot id: C6W4K3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

471854:DFER RS24890
gene id: 471854:DFER_RS24890
uniprot id: C6W7K3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

471854:DFER RS10145
gene id: 471854:DFER_RS10145
uniprot id: C6VXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

471854:DFER RS21080
gene id: 471854:DFER_RS21080
uniprot id: C6W0X9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS23130
gene id: 471854:DFER_RS23130
uniprot id: C6W3Z5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS03865
gene id: 471854:DFER_RS03865
uniprot id: C6W269
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

471854:DFER RS07835
gene id: 471854:DFER_RS07835
uniprot id: C6VSL0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS09390
gene id: 471854:DFER_RS09390
uniprot id: C6VW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS16945
gene id: 471854:DFER_RS16945
uniprot id: C6VSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS25995
gene id: 471854:DFER_RS25995
uniprot id: C6VSI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

471854:DFER RS08425
gene id: 471854:DFER_RS08425
uniprot id: C6VTK6
names: Similarity
messages: Belongs to the peptidase S9C family.

471854:DFER RS20975
gene id: 471854:DFER_RS20975
uniprot id: C6W0W0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06000
gene id: 471854:DFER_RS06000
uniprot id: C6W5A5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS16260
gene id: 471854:DFER_RS16260
uniprot id: C6VRX6
names: Similarity
messages: Belongs to the IMPACT family.

471854:DFER RS15010
gene id: 471854:DFER_RS15010
uniprot id: C6W6B0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS22560
gene id: 471854:DFER_RS22560
uniprot id: C6W318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

471854:DFER RS11300
gene id: 471854:DFER_RS11300
uniprot id: C6VZN6
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS16085
gene id: 471854:DFER_RS16085
uniprot id: C6W7I5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

471854:DFER RS28555
gene id: 471854:DFER_RS28555
uniprot id: C6VY10
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS27685
gene id: 471854:DFER_RS27685
uniprot id: C6VVK5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13030
gene id: 471854:DFER_RS13030
uniprot id: C6W2K1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471854:DFER RS01995
gene id: 471854:DFER_RS01995
uniprot id: C6VYJ4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS21340
gene id: 471854:DFER_RS21340
uniprot id: C6W129
names: Similarity
messages: Belongs to the oxoprolinase family.

471854:DFER RS11005
gene id: 471854:DFER_RS11005
uniprot id: C6VYV2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS22910
gene id: 471854:DFER_RS22910
uniprot id: C6W3V1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS12700
gene id: 471854:DFER_RS12700
uniprot id: C6W1Q9
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

471854:DFER RS13095
gene id: 471854:DFER_RS13095
uniprot id: C6W2L4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

471854:DFER RS01655
gene id: 471854:DFER_RS01655
uniprot id: C6VYC6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS15820
gene id: 471854:DFER_RS15820
uniprot id: C6W7D0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS02185
gene id: 471854:DFER_RS02185
uniprot id: C6VZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

471854:DFER RS24440
gene id: 471854:DFER_RS24440
uniprot id: C6W6P5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS12120
gene id: 471854:DFER_RS12120
uniprot id: C6W0R8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06150
gene id: 471854:DFER_RS06150
uniprot id: C6W614
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS24840
gene id: 471854:DFER_RS24840
uniprot id: C6W6X5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

471854:DFER RS20190
gene id: 471854:DFER_RS20190
uniprot id: C6VZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

471854:DFER RS23090
gene id: 471854:DFER_RS23090
uniprot id: C6W3Y7
names: Similarity
messages: Belongs to the peptidase S41A family.

471854:DFER RS15150
gene id: 471854:DFER_RS15150
uniprot id: C6W6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

471854:DFER RS25055
gene id: 471854:DFER_RS25055
uniprot id: C6W7N6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

471854:DFER RS18460
gene id: 471854:DFER_RS18460
uniprot id: C6VVA3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

471854:DFER RS28705
gene id: 471854:DFER_RS28705
uniprot id: C6VY40
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

471854:DFER RS10530
gene id: 471854:DFER_RS10530
uniprot id: C6VYK6
names: Similarity
messages: Belongs to the RuBisCO large chain family.

471854:DFER RS24355
gene id: 471854:DFER_RS24355
uniprot id: C6W6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

471854:DFER RS06905
gene id: 471854:DFER_RS06905
uniprot id: C6W737
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

471854:DFER RS07135
gene id: 471854:DFER_RS07135
uniprot id: C6VRJ1
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS14155
gene id: 471854:DFER_RS14155
uniprot id: C6W4H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

471854:DFER RS21215
gene id: 471854:DFER_RS21215
uniprot id: C6W104
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06130
gene id: 471854:DFER_RS06130
uniprot id: C6W610
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

471854:DFER RS21910
gene id: 471854:DFER_RS21910
uniprot id: C6W225
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

471854:DFER RS24335
gene id: 471854:DFER_RS24335
uniprot id: C6W6M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

471854:DFER RS17420
gene id: 471854:DFER_RS17420
uniprot id: C6VTV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

471854:DFER RS13230
gene id: 471854:DFER_RS13230
uniprot id: C6W2P1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS00520
gene id: 471854:DFER_RS00520
uniprot id: C6VVS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

471854:DFER RS01610
gene id: 471854:DFER_RS01610
uniprot id: C6VYB7
names: Similarity
messages: Belongs to the cytochrome P450 family.

471854:DFER RS22230
gene id: 471854:DFER_RS22230
uniprot id: C6W2U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

471854:DFER RS24865
gene id: 471854:DFER_RS24865
uniprot id: C6W7J7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS05955
gene id: 471854:DFER_RS05955
uniprot id: C6W596
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

471854:DFER RS05745
gene id: 471854:DFER_RS05745
uniprot id: C6W554
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS24950
gene id: 471854:DFER_RS24950
uniprot id: C6W7L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS19665
gene id: 471854:DFER_RS19665
uniprot id: C6VXX5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS25440
gene id: 471854:DFER_RS25440
uniprot id: C6VS71
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS05430
gene id: 471854:DFER_RS05430
uniprot id: C6W4B3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS14755
gene id: 471854:DFER_RS14755
uniprot id: C6W5I3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

471854:DFER RS17110
gene id: 471854:DFER_RS17110
uniprot id: C6VT20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

471854:DFER RS07810
gene id: 471854:DFER_RS07810
uniprot id: C6VSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS18250
gene id: 471854:DFER_RS18250
uniprot id: C6VV62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

471854:DFER RS20555
gene id: 471854:DFER_RS20555
uniprot id: C6W007
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471854:DFER RS07375
gene id: 471854:DFER_RS07375
uniprot id: C6VRN8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS20150
gene id: 471854:DFER_RS20150
uniprot id: C6VZ47
names: Similarity
messages: Belongs to the RecJ family.

471854:DFER RS23295
gene id: 471854:DFER_RS23295
uniprot id: C6W4Q5
names: Similarity
messages: Belongs to the DtxR/MntR family.

471854:DFER RS21515
gene id: 471854:DFER_RS21515
uniprot id: C6W1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

471854:DFER RS02085
gene id: 471854:DFER_RS02085
uniprot id: C6VZ80
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

471854:DFER RS26605
gene id: 471854:DFER_RS26605
uniprot id: C6VTG4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

471854:DFER RS12025
gene id: 471854:DFER_RS12025
uniprot id: C6W0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS04900
gene id: 471854:DFER_RS04900
uniprot id: C6W407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

471854:DFER RS22920
gene id: 471854:DFER_RS22920
uniprot id: C6W3V3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471854:DFER RS24410
gene id: 471854:DFER_RS24410
uniprot id: C6W6N9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS21675
gene id: 471854:DFER_RS21675
uniprot id: C6W1X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

471854:DFER RS12720
gene id: 471854:DFER_RS12720
uniprot id: C6W1R3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471854:DFER RS12835
gene id: 471854:DFER_RS12835
uniprot id: C6W2G2
names: Similarity
messages: Belongs to the YoeB family.

471854:DFER RS20015
gene id: 471854:DFER_RS20015
uniprot id: C6VZ21
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

471854:DFER RS28955
gene id: 471854:DFER_RS28955
uniprot id: C6VY90
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471854:DFER RS25235
gene id: 471854:DFER_RS25235
uniprot id: C6W7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

471854:DFER RS00200
gene id: 471854:DFER_RS00200
uniprot id: C6VUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS26995
gene id: 471854:DFER_RS26995
uniprot id: C6VUC4
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS21590
gene id: 471854:DFER_RS21590
uniprot id: C6W1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

471854:DFER RS16975
gene id: 471854:DFER_RS16975
uniprot id: C6VSZ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS03835
gene id: 471854:DFER_RS03835
uniprot id: C6W263
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS25710
gene id: 471854:DFER_RS25710
uniprot id: C6VSC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

471854:DFER RS27435
gene id: 471854:DFER_RS27435
uniprot id: C6VVF7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

471854:DFER RS14740
gene id: 471854:DFER_RS14740
uniprot id: C6W5I0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

471854:DFER RS14475
gene id: 471854:DFER_RS14475
uniprot id: C6W5C7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

471854:DFER RS08760
gene id: 471854:DFER_RS08760
uniprot id: C6VTS4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS26350
gene id: 471854:DFER_RS26350
uniprot id: C6VTB5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18990
gene id: 471854:DFER_RS18990
uniprot id: C6VWJ0
names: Similarity
messages: Belongs to the aspartokinase family.

471854:DFER RS20300
gene id: 471854:DFER_RS20300
uniprot id: C6VZV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS18305
gene id: 471854:DFER_RS18305
uniprot id: C6VV73
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471854:DFER RS22520
gene id: 471854:DFER_RS22520
uniprot id: C6W310
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

471854:DFER RS17870
gene id: 471854:DFER_RS17870
uniprot id: C6VU41
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

471854:DFER RS03690
gene id: 471854:DFER_RS03690
uniprot id: C6W1E9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS19815
gene id: 471854:DFER_RS19815
uniprot id: C6VYY1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

471854:DFER RS21565
gene id: 471854:DFER_RS21565
uniprot id: C6W1V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

471854:DFER RS25585
gene id: 471854:DFER_RS25585
uniprot id: C6VSA0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS05365
gene id: 471854:DFER_RS05365
uniprot id: C6W4A0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS13520
gene id: 471854:DFER_RS13520
uniprot id: C6W3H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

471854:DFER RS13875
gene id: 471854:DFER_RS13875
uniprot id: C6W4C0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS17285
gene id: 471854:DFER_RS17285
uniprot id: C6VT50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

471854:DFER RS25355
gene id: 471854:DFER_RS25355
uniprot id: C6W7U6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

471854:DFER RS10355
gene id: 471854:DFER_RS10355
uniprot id: C6VXI3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

471854:DFER RS00160
gene id: 471854:DFER_RS00160
uniprot id: C6VUJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

471854:DFER RS21755
gene id: 471854:DFER_RS21755
uniprot id: C6W1Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

471854:DFER RS26845
gene id: 471854:DFER_RS26845
uniprot id: C6VU94
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

471854:DFER RS23510
gene id: 471854:DFER_RS23510
uniprot id: C6W4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS26910
gene id: 471854:DFER_RS26910
uniprot id: C6VUA7
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS27995
gene id: 471854:DFER_RS27995
uniprot id: C6VWP7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS08520
gene id: 471854:DFER_RS08520
uniprot id: C6VTM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS22655
gene id: 471854:DFER_RS22655
uniprot id: C6W3Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

471854:DFER RS14555
gene id: 471854:DFER_RS14555
uniprot id: C6W5E3
names: Similarity
messages: Belongs to the Dps family.

471854:DFER RS19645
gene id: 471854:DFER_RS19645
uniprot id: C6VXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

471854:DFER RS06880
gene id: 471854:DFER_RS06880
uniprot id: C6W732
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS12350
gene id: 471854:DFER_RS12350
uniprot id: C6W1J0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS16880
gene id: 471854:DFER_RS16880
uniprot id: C6VSX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS11555
gene id: 471854:DFER_RS11555
uniprot id: C6VZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm

471854:DFER RS26810
gene id: 471854:DFER_RS26810
uniprot id: C6VU86
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

471854:DFER RS28205
gene id: 471854:DFER_RS28205
uniprot id: C6VWU1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

471854:DFER RS23255
gene id: 471854:DFER_RS23255
uniprot id: C6W4P7
names: Similarity
messages: Belongs to the glutamine synthetase family.

471854:DFER RS02305
gene id: 471854:DFER_RS02305
uniprot id: C6VZC4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

471854:DFER RS03485
gene id: 471854:DFER_RS03485
uniprot id: C6W1A8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

471854:DFER RS17330
gene id: 471854:DFER_RS17330
uniprot id: C6VTT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS19935
gene id: 471854:DFER_RS19935
uniprot id: C6VZ06
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS05635
gene id: 471854:DFER_RS05635
uniprot id: C6W531
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

471854:DFER RS19015
gene id: 471854:DFER_RS19015
uniprot id: C6VWJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471854:DFER RS19485
gene id: 471854:DFER_RS19485
uniprot id: C6VXT8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

471854:DFER RS08600
gene id: 471854:DFER_RS08600
uniprot id: C6VTP1
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS19550
gene id: 471854:DFER_RS19550
uniprot id: C6VXV1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS08115
gene id: 471854:DFER_RS08115
uniprot id: C6VSR6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS23450
gene id: 471854:DFER_RS23450
uniprot id: C6W4T6
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS09880
gene id: 471854:DFER_RS09880
uniprot id: C6VW99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

471854:DFER RS20450
gene id: 471854:DFER_RS20450
uniprot id: C6VZY6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

471854:DFER RS17640
gene id: 471854:DFER_RS17640
uniprot id: C6VTZ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

471854:DFER RS22110
gene id: 471854:DFER_RS22110
uniprot id: C6W2S5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

471854:DFER RS10605
gene id: 471854:DFER_RS10605
uniprot id: C6VYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS10755
gene id: 471854:DFER_RS10755
uniprot id: C6VYQ3
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS02195
gene id: 471854:DFER_RS02195
uniprot id: C6VZA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471854:DFER RS00025
gene id: 471854:DFER_RS00025
uniprot id: C6VUG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

471854:DFER RS17325
gene id: 471854:DFER_RS17325
uniprot id: C6VTT5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS05260
gene id: 471854:DFER_RS05260
uniprot id: C6W479
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

471854:DFER RS05855
gene id: 471854:DFER_RS05855
uniprot id: C6W576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

471854:DFER RS17085
gene id: 471854:DFER_RS17085
uniprot id: C6VT15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

471854:DFER RS19675
gene id: 471854:DFER_RS19675
uniprot id: C6VXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

471854:DFER RS21725
gene id: 471854:DFER_RS21725
uniprot id: C6W1Y7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

471854:DFER RS03985
gene id: 471854:DFER_RS03985
uniprot id: C6W293
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS22555
gene id: 471854:DFER_RS22555
uniprot id: C6W317
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS19700
gene id: 471854:DFER_RS19700
uniprot id: C6VXY2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS04910
gene id: 471854:DFER_RS04910
uniprot id: C6W409
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS19035
gene id: 471854:DFER_RS19035
uniprot id: C6VWJ9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

471854:DFER RS21500
gene id: 471854:DFER_RS21500
uniprot id: C6W1U1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS12200
gene id: 471854:DFER_RS12200
uniprot id: C6W0T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS16810
gene id: 471854:DFER_RS16810
uniprot id: C6VSW1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18950
gene id: 471854:DFER_RS18950
uniprot id: C6VWI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

471854:DFER RS17570
gene id: 471854:DFER_RS17570
uniprot id: C6VTY2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

471854:DFER RS28730
gene id: 471854:DFER_RS28730
uniprot id: C6VY45
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

471854:DFER RS17105
gene id: 471854:DFER_RS17105
uniprot id: C6VT19
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

471854:DFER RS07980
gene id: 471854:DFER_RS07980
uniprot id: C6VSN9
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS01420
gene id: 471854:DFER_RS01420
uniprot id: C6VX86
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

471854:DFER RS21630
gene id: 471854:DFER_RS21630
uniprot id: C6W1W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

471854:DFER RS23990
gene id: 471854:DFER_RS23990
uniprot id: C6W5S7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

471854:DFER RS12750
gene id: 471854:DFER_RS12750
uniprot id: C6W1R9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

471854:DFER RS00490
gene id: 471854:DFER_RS00490
uniprot id: C6VVR6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

471854:DFER RS03995
gene id: 471854:DFER_RS03995
uniprot id: C6W295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

471854:DFER RS28075
gene id: 471854:DFER_RS28075
uniprot id: C6VWR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

471854:DFER RS20945
gene id: 471854:DFER_RS20945
uniprot id: C6W0V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

471854:DFER RS07195
gene id: 471854:DFER_RS07195
uniprot id: C6VRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS12250
gene id: 471854:DFER_RS12250
uniprot id: C6W1H0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS24130
gene id: 471854:DFER_RS24130
uniprot id: C6W5V5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13455
gene id: 471854:DFER_RS13455
uniprot id: C6W3F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS20460
gene id: 471854:DFER_RS20460
uniprot id: C6VZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS28745
gene id: 471854:DFER_RS28745
uniprot id: C6VY48
names: Subcellular Location Annotation
messages: Cell inner membrane

471854:DFER RS18325
gene id: 471854:DFER_RS18325
uniprot id: C6VV77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

471854:DFER RS08145
gene id: 471854:DFER_RS08145
uniprot id: C6VSS2
names: Similarity
messages: Belongs to the universal stress protein A family.

471854:DFER RS05660
gene id: 471854:DFER_RS05660
uniprot id: C6W537
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS24330
gene id: 471854:DFER_RS24330
uniprot id: C6W6M3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

471854:DFER RS01605
gene id: 471854:DFER_RS01605
uniprot id: C6VYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

471854:DFER RS15855
gene id: 471854:DFER_RS15855
uniprot id: C6W7D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

471854:DFER RS25465
gene id: 471854:DFER_RS25465
uniprot id: C6VS76
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

471854:DFER RS18310
gene id: 471854:DFER_RS18310
uniprot id: C6VV74
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

471854:DFER RS14880
gene id: 471854:DFER_RS14880
uniprot id: C6W5K8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS16800
gene id: 471854:DFER_RS16800
uniprot id: C6VSV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS21050
gene id: 471854:DFER_RS21050
uniprot id: C6W0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS20420
gene id: 471854:DFER_RS20420
uniprot id: C6VZY0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

471854:DFER RS13505
gene id: 471854:DFER_RS13505
uniprot id: C6W3G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471854:DFER RS05525
gene id: 471854:DFER_RS05525
uniprot id: C6W509
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS22020
gene id: 471854:DFER_RS22020
uniprot id: C6W246
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS26895
gene id: 471854:DFER_RS26895
uniprot id: C6VUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm

471854:DFER RS13285
gene id: 471854:DFER_RS13285
uniprot id: C6W2Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

471854:DFER RS12625
gene id: 471854:DFER_RS12625
uniprot id: C6W1P5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS23775
gene id: 471854:DFER_RS23775
uniprot id: C6W5N4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

471854:DFER RS08080
gene id: 471854:DFER_RS08080
uniprot id: C6VSQ9
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS09410
gene id: 471854:DFER_RS09410
uniprot id: C6VW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

471854:DFER RS20155
gene id: 471854:DFER_RS20155
uniprot id: C6VZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

471854:DFER RS01860
gene id: 471854:DFER_RS01860
uniprot id: C6VYG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

471854:DFER RS14310
gene id: 471854:DFER_RS14310
uniprot id: C6W4L0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

471854:DFER RS19155
gene id: 471854:DFER_RS19155
uniprot id: C6VXM1
names: Similarity
messages: Belongs to the peptidase S41A family.

471854:DFER RS02870
gene id: 471854:DFER_RS02870
uniprot id: C6W0B0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS17205
gene id: 471854:DFER_RS17205
uniprot id: C6VT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

471854:DFER RS23360
gene id: 471854:DFER_RS23360
uniprot id: C6W4R8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

471854:DFER RS12535
gene id: 471854:DFER_RS12535
uniprot id: C6W1M7
names: Similarity
messages: Belongs to the YjiK family.

471854:DFER RS27430
gene id: 471854:DFER_RS27430
uniprot id: C6VVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

471854:DFER RS22805
gene id: 471854:DFER_RS22805
uniprot id: C6W3T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

471854:DFER RS10600
gene id: 471854:DFER_RS10600
uniprot id: C6VYM0
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS01210
gene id: 471854:DFER_RS01210
uniprot id: C6VX45
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

471854:DFER RS22770
gene id: 471854:DFER_RS22770
uniprot id: C6W3S6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS02350
gene id: 471854:DFER_RS02350
uniprot id: C6VZD3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

471854:DFER RS25145
gene id: 471854:DFER_RS25145
uniprot id: C6W7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

471854:DFER RS21880
gene id: 471854:DFER_RS21880
uniprot id: C6W219
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

471854:DFER RS18560
gene id: 471854:DFER_RS18560
uniprot id: C6VWB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

471854:DFER RS26125
gene id: 471854:DFER_RS26125
uniprot id: C6VT73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

471854:DFER RS24470
gene id: 471854:DFER_RS24470
uniprot id: C6W6Q1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

471854:DFER RS27805
gene id: 471854:DFER_RS27805
uniprot id: C6VVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

471854:DFER RS27650
gene id: 471854:DFER_RS27650
uniprot id: C6VVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS24570
gene id: 471854:DFER_RS24570
uniprot id: C6W6S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

471854:DFER RS22355
gene id: 471854:DFER_RS22355
uniprot id: C6W2X7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

471854:DFER RS10320
gene id: 471854:DFER_RS10320
uniprot id: C6VXH6
names: Similarity
messages: Belongs to the peptidase U62 family.

471854:DFER RS06355
gene id: 471854:DFER_RS06355
uniprot id: C6W655
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

471854:DFER RS29355
gene id: 471854:DFER_RS29355
uniprot id: C6VT75
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

471854:DFER RS21660
gene id: 471854:DFER_RS21660
uniprot id: C6W1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

471854:DFER RS00195
gene id: 471854:DFER_RS00195
uniprot id: C6VUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

471854:DFER RS14130
gene id: 471854:DFER_RS14130
uniprot id: C6W4H3
names: Similarity
messages: Belongs to the YoeB family.

471854:DFER RS07345
gene id: 471854:DFER_RS07345
uniprot id: C6VRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

471854:DFER RS26580
gene id: 471854:DFER_RS26580
uniprot id: C6VTF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS22085
gene id: 471854:DFER_RS22085
uniprot id: C6W2S0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471854:DFER RS02540
gene id: 471854:DFER_RS02540
uniprot id: C6VZG9
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

471854:DFER RS07665
gene id: 471854:DFER_RS07665
uniprot id: C6VRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS28185
gene id: 471854:DFER_RS28185
uniprot id: C6VWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

471854:DFER RS00380
gene id: 471854:DFER_RS00380
uniprot id: C6VVP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS05095
gene id: 471854:DFER_RS05095
uniprot id: C6W447
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS10985
gene id: 471854:DFER_RS10985
uniprot id: C6VYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS21665
gene id: 471854:DFER_RS21665
uniprot id: C6W1X4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

471854:DFER RS15970
gene id: 471854:DFER_RS15970
uniprot id: C6W7G2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

471854:DFER RS18745
gene id: 471854:DFER_RS18745
uniprot id: C6VWE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

471854:DFER RS17270
gene id: 471854:DFER_RS17270
uniprot id: C6VT47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

471854:DFER RS13710
gene id: 471854:DFER_RS13710
uniprot id: C6W3L1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471854:DFER RS12570
gene id: 471854:DFER_RS12570
uniprot id: C6W1N4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

471854:DFER RS01055
gene id: 471854:DFER_RS01055
uniprot id: C6VX14
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

471854:DFER RS15795
gene id: 471854:DFER_RS15795
uniprot id: C6W7C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

471854:DFER RS28130
gene id: 471854:DFER_RS28130
uniprot id: C6VWS6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS20600
gene id: 471854:DFER_RS20600
uniprot id: C6W016
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS23425
gene id: 471854:DFER_RS23425
uniprot id: C6W4T1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

471854:DFER RS24900
gene id: 471854:DFER_RS24900
uniprot id: C6W7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

471854:DFER RS21780
gene id: 471854:DFER_RS21780
uniprot id: C6W1Z9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

471854:DFER RS20335
gene id: 471854:DFER_RS20335
uniprot id: C6VZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS27135
gene id: 471854:DFER_RS27135
uniprot id: C6VUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

471854:DFER RS07035
gene id: 471854:DFER_RS07035
uniprot id: C6W765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS03920
gene id: 471854:DFER_RS03920
uniprot id: C6W280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS12015
gene id: 471854:DFER_RS12015
uniprot id: C6W0P8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS02240
gene id: 471854:DFER_RS02240
uniprot id: C6VZB1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

471854:DFER RS16680
gene id: 471854:DFER_RS16680
uniprot id: C6VS59
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

471854:DFER RS22995
gene id: 471854:DFER_RS22995
uniprot id: C6W3W8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS25485
gene id: 471854:DFER_RS25485
uniprot id: C6VS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS22720
gene id: 471854:DFER_RS22720
uniprot id: C6W3R6
names: Similarity
messages: Belongs to the IlvD/Edd family.

471854:DFER RS17625
gene id: 471854:DFER_RS17625
uniprot id: C6VTZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471854:DFER RS27885
gene id: 471854:DFER_RS27885
uniprot id: C6VWM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS11900
gene id: 471854:DFER_RS11900
uniprot id: C6W0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

471854:DFER RS19655
gene id: 471854:DFER_RS19655
uniprot id: C6VXX3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

471854:DFER RS05670
gene id: 471854:DFER_RS05670
uniprot id: C6W539
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

471854:DFER RS08940
gene id: 471854:DFER_RS08940
uniprot id: C6VUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

471854:DFER RS07405
gene id: 471854:DFER_RS07405
uniprot id: C6VRP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS24295
gene id: 471854:DFER_RS24295
uniprot id: C6W5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

471854:DFER RS11995
gene id: 471854:DFER_RS11995
uniprot id: C6W0P4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS15790
gene id: 471854:DFER_RS15790
uniprot id: C6W7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

471854:DFER RS08165
gene id: 471854:DFER_RS08165
uniprot id: C6VSS6
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS24980
gene id: 471854:DFER_RS24980
uniprot id: C6W7M1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13470
gene id: 471854:DFER_RS13470
uniprot id: C6W3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

471854:DFER RS19545
gene id: 471854:DFER_RS19545
uniprot id: C6VXV0
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

471854:DFER RS06820
gene id: 471854:DFER_RS06820
uniprot id: C6W720
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS25925
gene id: 471854:DFER_RS25925
uniprot id: C6VSG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS25015
gene id: 471854:DFER_RS25015
uniprot id: C6W7M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

471854:DFER RS06970
gene id: 471854:DFER_RS06970
uniprot id: C6W751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS25685
gene id: 471854:DFER_RS25685
uniprot id: C6VSB8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS05380
gene id: 471854:DFER_RS05380
uniprot id: C6W4A3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

471854:DFER RS20710
gene id: 471854:DFER_RS20710
uniprot id: C6W039
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS11840
gene id: 471854:DFER_RS11840
uniprot id: C6W0L2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS17305
gene id: 471854:DFER_RS17305
uniprot id: C6VTT1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS25320
gene id: 471854:DFER_RS25320
uniprot id: C6W7T9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18685
gene id: 471854:DFER_RS18685
uniprot id: C6VWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

471854:DFER RS18385
gene id: 471854:DFER_RS18385
uniprot id: C6VV88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS16635
gene id: 471854:DFER_RS16635
uniprot id: C6VS51
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

471854:DFER RS05405
gene id: 471854:DFER_RS05405
uniprot id: C6W4A8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

471854:DFER RS17375
gene id: 471854:DFER_RS17375
uniprot id: C6VTU4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

471854:DFER RS22245
gene id: 471854:DFER_RS22245
uniprot id: C6W2V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

471854:DFER RS25880
gene id: 471854:DFER_RS25880
uniprot id: C6VSF7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

471854:DFER RS22010
gene id: 471854:DFER_RS22010
uniprot id: C6W244
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

471854:DFER RS10350
gene id: 471854:DFER_RS10350
uniprot id: C6VXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

471854:DFER RS12355
gene id: 471854:DFER_RS12355
uniprot id: C6W1J1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS12900
gene id: 471854:DFER_RS12900
uniprot id: C6W2H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

471854:DFER RS15105
gene id: 471854:DFER_RS15105
uniprot id: C6W6C9
names: Similarity
messages: Belongs to the hyi family.

471854:DFER RS25200
gene id: 471854:DFER_RS25200
uniprot id: C6W7R5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS24870
gene id: 471854:DFER_RS24870
uniprot id: C6W7J8
names: Similarity
messages: Belongs to the ArsC family.

471854:DFER RS24000
gene id: 471854:DFER_RS24000
uniprot id: C6W5S9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

471854:DFER RS23190
gene id: 471854:DFER_RS23190
uniprot id: C6W4N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

471854:DFER RS10030
gene id: 471854:DFER_RS10030
uniprot id: C6VXB8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

471854:DFER RS06100
gene id: 471854:DFER_RS06100
uniprot id: C6W604
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

471854:DFER RS25955
gene id: 471854:DFER_RS25955
uniprot id: C6VSH2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

471854:DFER RS24855
gene id: 471854:DFER_RS24855
uniprot id: C6W7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

471854:DFER RS05675
gene id: 471854:DFER_RS05675
uniprot id: C6W540
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS05025
gene id: 471854:DFER_RS05025
uniprot id: C6W432
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS07850
gene id: 471854:DFER_RS07850
uniprot id: C6VSL3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS10100
gene id: 471854:DFER_RS10100
uniprot id: C6VXD2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS01030
gene id: 471854:DFER_RS01030
uniprot id: C6VX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

471854:DFER RS01765
gene id: 471854:DFER_RS01765
uniprot id: C6VYE6
names: Similarity
messages: Belongs to the pirin family.

471854:DFER RS21270
gene id: 471854:DFER_RS21270
uniprot id: C6W115
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS14360
gene id: 471854:DFER_RS14360
uniprot id: C6W4M0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

471854:DFER RS25970
gene id: 471854:DFER_RS25970
uniprot id: C6VSH5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS18140
gene id: 471854:DFER_RS18140
uniprot id: C6VV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

471854:DFER RS14355
gene id: 471854:DFER_RS14355
uniprot id: C6W4L9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

471854:DFER RS17875
gene id: 471854:DFER_RS17875
uniprot id: C6VU42
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

471854:DFER RS02035
gene id: 471854:DFER_RS02035
uniprot id: C6VYK2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

471854:DFER RS27030
gene id: 471854:DFER_RS27030
uniprot id: C6VUD1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS07990
gene id: 471854:DFER_RS07990
uniprot id: C6VSP1
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

471854:DFER RS02210
gene id: 471854:DFER_RS02210
uniprot id: C6VZA5
names: Similarity
messages: Belongs to the glutamine synthetase family.

471854:DFER RS11295
gene id: 471854:DFER_RS11295
uniprot id: C6VZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS25075
gene id: 471854:DFER_RS25075
uniprot id: C6W7P0
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

471854:DFER RS20385
gene id: 471854:DFER_RS20385
uniprot id: C6VZX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

471854:DFER RS25455
gene id: 471854:DFER_RS25455
uniprot id: C6VS74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

471854:DFER RS14050
gene id: 471854:DFER_RS14050
uniprot id: C6W4F7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS15670
gene id: 471854:DFER_RS15670
uniprot id: C6W7A0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17120
gene id: 471854:DFER_RS17120
uniprot id: C6VT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

471854:DFER RS21295
gene id: 471854:DFER_RS21295
uniprot id: C6W120
names: Similarity
messages: Belongs to the proline racemase family.

471854:DFER RS19780
gene id: 471854:DFER_RS19780
uniprot id: C6VYX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

471854:DFER RS16625
gene id: 471854:DFER_RS16625
uniprot id: C6VS49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS05695
gene id: 471854:DFER_RS05695
uniprot id: C6W544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

471854:DFER RS10435
gene id: 471854:DFER_RS10435
uniprot id: C6VXJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS18215
gene id: 471854:DFER_RS18215
uniprot id: C6VV55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

471854:DFER RS21235
gene id: 471854:DFER_RS21235
uniprot id: C6W108
names: Similarity
messages: Belongs to the RutC family.

471854:DFER RS08085
gene id: 471854:DFER_RS08085
uniprot id: C6VSR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS16350
gene id: 471854:DFER_RS16350
uniprot id: C6VRZ4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS04145
gene id: 471854:DFER_RS04145
uniprot id: C6W2B9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

471854:DFER RS21735
gene id: 471854:DFER_RS21735
uniprot id: C6W1Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

471854:DFER RS13600
gene id: 471854:DFER_RS13600
uniprot id: C6W3I8
names: Similarity
messages: Belongs to the sigma-54 factor family.

471854:DFER RS20815
gene id: 471854:DFER_RS20815
uniprot id: C6W059
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS23595
gene id: 471854:DFER_RS23595
uniprot id: C6W4W4
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS14110
gene id: 471854:DFER_RS14110
uniprot id: C6W4G9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS07805
gene id: 471854:DFER_RS07805
uniprot id: C6VSK4
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS22420
gene id: 471854:DFER_RS22420
uniprot id: C6W2Y9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS24165
gene id: 471854:DFER_RS24165
uniprot id: C6W5W2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS24185
gene id: 471854:DFER_RS24185
uniprot id: C6W5W6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS24715
gene id: 471854:DFER_RS24715
uniprot id: C6W6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

471854:DFER RS12655
gene id: 471854:DFER_RS12655
uniprot id: C6W1Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

471854:DFER RS20305
gene id: 471854:DFER_RS20305
uniprot id: C6VZV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS28365
gene id: 471854:DFER_RS28365
uniprot id: C6VWX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

471854:DFER RS17840
gene id: 471854:DFER_RS17840
uniprot id: C6VU35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

471854:DFER RS02000
gene id: 471854:DFER_RS02000
uniprot id: C6VYJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

471854:DFER RS14075
gene id: 471854:DFER_RS14075
uniprot id: C6W4G2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

471854:DFER RS13350
gene id: 471854:DFER_RS13350
uniprot id: C6W3D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS09865
gene id: 471854:DFER_RS09865
uniprot id: C6VW96
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

471854:DFER RS23910
gene id: 471854:DFER_RS23910
uniprot id: C6W5R1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

471854:DFER RS18430
gene id: 471854:DFER_RS18430
uniprot id: C6VV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

471854:DFER RS01190
gene id: 471854:DFER_RS01190
uniprot id: C6VX41
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

471854:DFER RS17845
gene id: 471854:DFER_RS17845
uniprot id: C6VU36
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13185
gene id: 471854:DFER_RS13185
uniprot id: C6W2N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

471854:DFER RS09745
gene id: 471854:DFER_RS09745
uniprot id: C6VW71
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

471854:DFER RS28315
gene id: 471854:DFER_RS28315
uniprot id: C6VWW3
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS00815
gene id: 471854:DFER_RS00815
uniprot id: C6VVY3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS01095
gene id: 471854:DFER_RS01095
uniprot id: C6VX22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

471854:DFER RS21670
gene id: 471854:DFER_RS21670
uniprot id: C6W1X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

471854:DFER RS21240
gene id: 471854:DFER_RS21240
uniprot id: C6W109
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS16410
gene id: 471854:DFER_RS16410
uniprot id: C6VS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS19355
gene id: 471854:DFER_RS19355
uniprot id: C6VXR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS14945
gene id: 471854:DFER_RS14945
uniprot id: C6W5M0
names: Similarity
messages: Belongs to the DapA family.

471854:DFER RS08890
gene id: 471854:DFER_RS08890
uniprot id: C6VUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS09905
gene id: 471854:DFER_RS09905
uniprot id: C6VWA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

471854:DFER RS28740
gene id: 471854:DFER_RS28740
uniprot id: C6VY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

471854:DFER RS03790
gene id: 471854:DFER_RS03790
uniprot id: C6W253
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

471854:DFER RS22130
gene id: 471854:DFER_RS22130
uniprot id: C6W2S9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

471854:DFER RS24285
gene id: 471854:DFER_RS24285
uniprot id: C6W5Y6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

471854:DFER RS05105
gene id: 471854:DFER_RS05105
uniprot id: C6W449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

471854:DFER RS02975
gene id: 471854:DFER_RS02975
uniprot id: C6W0C9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS04030
gene id: 471854:DFER_RS04030
uniprot id: C6W2A2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS14660
gene id: 471854:DFER_RS14660
uniprot id: C6W5G4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

471854:DFER RS19180
gene id: 471854:DFER_RS19180
uniprot id: C6VXM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471854:DFER RS25295
gene id: 471854:DFER_RS25295
uniprot id: C6W7T4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

471854:DFER RS24560
gene id: 471854:DFER_RS24560
uniprot id: C6W6R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

471854:DFER RS20800
gene id: 471854:DFER_RS20800
uniprot id: C6W056
names: Similarity
messages: Belongs to the AIR synthase family.

471854:DFER RS11825
gene id: 471854:DFER_RS11825
uniprot id: C6W0K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

471854:DFER RS23230
gene id: 471854:DFER_RS23230
uniprot id: C6W4P2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

471854:DFER RS22150
gene id: 471854:DFER_RS22150
uniprot id: C6W2T3
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

471854:DFER RS02555
gene id: 471854:DFER_RS02555
uniprot id: C6VZH2
names: Similarity
messages: Belongs to the manganese catalase family.

471854:DFER RS13900
gene id: 471854:DFER_RS13900
uniprot id: C6W4C6
names: Similarity
messages: Belongs to the NodU/CmcH family.

471854:DFER RS07985
gene id: 471854:DFER_RS07985
uniprot id: C6VSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS09050
gene id: 471854:DFER_RS09050
uniprot id: C6VUT5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS25470
gene id: 471854:DFER_RS25470
uniprot id: C6VS77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

471854:DFER RS10680
gene id: 471854:DFER_RS10680
uniprot id: C6VYN7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS14950
gene id: 471854:DFER_RS14950
uniprot id: C6W5M1
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS00990
gene id: 471854:DFER_RS00990
uniprot id: C6VX00
names: Similarity
messages: Belongs to the DEAD box helicase family.

471854:DFER RS25105
gene id: 471854:DFER_RS25105
uniprot id: C6W7P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

471854:DFER RS05395
gene id: 471854:DFER_RS05395
uniprot id: C6W4A6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

471854:DFER RS10535
gene id: 471854:DFER_RS10535
uniprot id: C6VYK7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

471854:DFER RS17200
gene id: 471854:DFER_RS17200
uniprot id: C6VT34
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17645
gene id: 471854:DFER_RS17645
uniprot id: C6VTZ7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS10695
gene id: 471854:DFER_RS10695
uniprot id: C6VYP1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS13530
gene id: 471854:DFER_RS13530
uniprot id: C6W3H4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

471854:DFER RS16950
gene id: 471854:DFER_RS16950
uniprot id: C6VSZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS09315
gene id: 471854:DFER_RS09315
uniprot id: C6VUY7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS10555
gene id: 471854:DFER_RS10555
uniprot id: C6VYL1
names: Similarity
messages: Belongs to the FGGY kinase family.

471854:DFER RS11140
gene id: 471854:DFER_RS11140
uniprot id: C6VZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS21460
gene id: 471854:DFER_RS21460
uniprot id: C6W1T3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

471854:DFER RS20515
gene id: 471854:DFER_RS20515
uniprot id: C6VZZ9
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

471854:DFER RS03165
gene id: 471854:DFER_RS03165
uniprot id: C6W0G8
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS07830
gene id: 471854:DFER_RS07830
uniprot id: C6VSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

471854:DFER RS18965
gene id: 471854:DFER_RS18965
uniprot id: C6VWI4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

471854:DFER RS24300
gene id: 471854:DFER_RS24300
uniprot id: C6W5Y9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28240
gene id: 471854:DFER_RS28240
uniprot id: C6VWU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS22675
gene id: 471854:DFER_RS22675
uniprot id: C6W3Q7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS03460
gene id: 471854:DFER_RS03460
uniprot id: C6W1A3
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS05125
gene id: 471854:DFER_RS05125
uniprot id: C6W453
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS03825
gene id: 471854:DFER_RS03825
uniprot id: C6W261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS22825
gene id: 471854:DFER_RS22825
uniprot id: C6W3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

471854:DFER RS17335
gene id: 471854:DFER_RS17335
uniprot id: C6VTT7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

471854:DFER RS20820
gene id: 471854:DFER_RS20820
uniprot id: C6W060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS06450
gene id: 471854:DFER_RS06450
uniprot id: C6W675
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS23635
gene id: 471854:DFER_RS23635
uniprot id: C6W4X2
names: Similarity
messages: Belongs to the threonine aldolase family.

471854:DFER RS21745
gene id: 471854:DFER_RS21745
uniprot id: C6W1Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

471854:DFER RS25230
gene id: 471854:DFER_RS25230
uniprot id: C6W7S1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

471854:DFER RS14900
gene id: 471854:DFER_RS14900
uniprot id: C6W5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

471854:DFER RS06235
gene id: 471854:DFER_RS06235
uniprot id: C6W632
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

471854:DFER RS04830
gene id: 471854:DFER_RS04830
uniprot id: C6W3C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

471854:DFER RS13825
gene id: 471854:DFER_RS13825
uniprot id: C6W3N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

471854:DFER RS14605
gene id: 471854:DFER_RS14605
uniprot id: C6W5F3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS11690
gene id: 471854:DFER_RS11690
uniprot id: C6W0I1
names: Subunit
messages: Homodimer.

471854:DFER RS13705
gene id: 471854:DFER_RS13705
uniprot id: C6W3L0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

471854:DFER RS14835
gene id: 471854:DFER_RS14835
uniprot id: C6W5J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471854:DFER RS09895
gene id: 471854:DFER_RS09895
uniprot id: C6VWA2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

471854:DFER RS00755
gene id: 471854:DFER_RS00755
uniprot id: C6VVX0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

471854:DFER RS10700
gene id: 471854:DFER_RS10700
uniprot id: C6VYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS18985
gene id: 471854:DFER_RS18985
uniprot id: C6VWI9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

471854:DFER RS08395
gene id: 471854:DFER_RS08395
uniprot id: C6VTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS08710
gene id: 471854:DFER_RS08710
uniprot id: C6VTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS13020
gene id: 471854:DFER_RS13020
uniprot id: C6W2J9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

471854:DFER RS19505
gene id: 471854:DFER_RS19505
uniprot id: C6VXU2
names: Similarity
messages: Belongs to the peptidase S41A family.

471854:DFER RS17280
gene id: 471854:DFER_RS17280
uniprot id: C6VT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

471854:DFER RS22700
gene id: 471854:DFER_RS22700
uniprot id: C6W3R2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS11050
gene id: 471854:DFER_RS11050
uniprot id: C6VZI8
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS26815
gene id: 471854:DFER_RS26815
uniprot id: C6VU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

471854:DFER RS00740
gene id: 471854:DFER_RS00740
uniprot id: C6VVW7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

471854:DFER RS13085
gene id: 471854:DFER_RS13085
uniprot id: C6W2L2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

471854:DFER RS06395
gene id: 471854:DFER_RS06395
uniprot id: C6W663
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS24160
gene id: 471854:DFER_RS24160
uniprot id: C6W5W1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS16250
gene id: 471854:DFER_RS16250
uniprot id: C6VRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS17695
gene id: 471854:DFER_RS17695
uniprot id: C6VU07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

471854:DFER RS13515
gene id: 471854:DFER_RS13515
uniprot id: C6W3H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

471854:DFER RS00035
gene id: 471854:DFER_RS00035
uniprot id: C6VUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

471854:DFER RS21710
gene id: 471854:DFER_RS21710
uniprot id: C6W1Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

471854:DFER RS24970
gene id: 471854:DFER_RS24970
uniprot id: C6W7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

471854:DFER RS28045
gene id: 471854:DFER_RS28045
uniprot id: C6VWQ7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS08500
gene id: 471854:DFER_RS08500
uniprot id: C6VTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS00940
gene id: 471854:DFER_RS00940
uniprot id: C6VWZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS05795
gene id: 471854:DFER_RS05795
uniprot id: C6W564
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS09875
gene id: 471854:DFER_RS09875
uniprot id: C6VW98
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

471854:DFER RS00800
gene id: 471854:DFER_RS00800
uniprot id: C6VVX9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS20345
gene id: 471854:DFER_RS20345
uniprot id: C6VZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS08845
gene id: 471854:DFER_RS08845
uniprot id: C6VUP5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS26710
gene id: 471854:DFER_RS26710
uniprot id: C6VU67
names: Similarity
messages: Belongs to the YciI family.

471854:DFER RS00210
gene id: 471854:DFER_RS00210
uniprot id: C6VUK5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS28430
gene id: 471854:DFER_RS28430
uniprot id: C6VXY4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

471854:DFER RS08720
gene id: 471854:DFER_RS08720
uniprot id: C6VTR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS26150
gene id: 471854:DFER_RS26150
uniprot id: C6VT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

471854:DFER RS23120
gene id: 471854:DFER_RS23120
uniprot id: C6W3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

471854:DFER RS01355
gene id: 471854:DFER_RS01355
uniprot id: C6VX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

471854:DFER RS17390
gene id: 471854:DFER_RS17390
uniprot id: C6VTU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

471854:DFER RS19185
gene id: 471854:DFER_RS19185
uniprot id: C6VXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

471854:DFER RS22155
gene id: 471854:DFER_RS22155
uniprot id: C6W2T4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

471854:DFER RS19540
gene id: 471854:DFER_RS19540
uniprot id: C6VXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

471854:DFER RS26805
gene id: 471854:DFER_RS26805
uniprot id: C6VU85
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

471854:DFER RS15095
gene id: 471854:DFER_RS15095
uniprot id: C6W6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS04810
gene id: 471854:DFER_RS04810
uniprot id: C6W3C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS02250
gene id: 471854:DFER_RS02250
uniprot id: C6VZB3
names: Similarity
messages: Belongs to the CinA family.

471854:DFER RS21085
gene id: 471854:DFER_RS21085
uniprot id: C6W0Y0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471854:DFER RS18850
gene id: 471854:DFER_RS18850
uniprot id: C6VWG6
names: Similarity
messages: Belongs to the TrpC family.

471854:DFER RS14820
gene id: 471854:DFER_RS14820
uniprot id: C6W5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

471854:DFER RS13865
gene id: 471854:DFER_RS13865
uniprot id: C6W4B8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

471854:DFER RS13355
gene id: 471854:DFER_RS13355
uniprot id: C6W3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

471854:DFER RS26635
gene id: 471854:DFER_RS26635
uniprot id: C6VU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS04805
gene id: 471854:DFER_RS04805
uniprot id: C6W3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS06745
gene id: 471854:DFER_RS06745
uniprot id: C6W706
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

471854:DFER RS16855
gene id: 471854:DFER_RS16855
uniprot id: C6VSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS20970
gene id: 471854:DFER_RS20970
uniprot id: C6W0V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

471854:DFER RS03535
gene id: 471854:DFER_RS03535
uniprot id: C6W1B8
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS21695
gene id: 471854:DFER_RS21695
uniprot id: C6W1Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

471854:DFER RS20380
gene id: 471854:DFER_RS20380
uniprot id: C6VZX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

471854:DFER RS17020
gene id: 471854:DFER_RS17020
uniprot id: C6VT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS01480
gene id: 471854:DFER_RS01480
uniprot id: C6VY92
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS21305
gene id: 471854:DFER_RS21305
uniprot id: C6W122
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS15445
gene id: 471854:DFER_RS15445
uniprot id: C6W6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

471854:DFER RS05290
gene id: 471854:DFER_RS05290
uniprot id: C6W485
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

471854:DFER RS27930
gene id: 471854:DFER_RS27930
uniprot id: C6VWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

471854:DFER RS05975
gene id: 471854:DFER_RS05975
uniprot id: C6W5A0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

471854:DFER RS20180
gene id: 471854:DFER_RS20180
uniprot id: C6VZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

471854:DFER RS24210
gene id: 471854:DFER_RS24210
uniprot id: C6W5X1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS21715
gene id: 471854:DFER_RS21715
uniprot id: C6W1Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

471854:DFER RS19495
gene id: 471854:DFER_RS19495
uniprot id: C6VXU0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

471854:DFER RS01600
gene id: 471854:DFER_RS01600
uniprot id: C6VYB5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

471854:DFER RS29885
gene id: 471854:DFER_RS29885
uniprot id: C6VUP1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

471854:DFER RS17095
gene id: 471854:DFER_RS17095
uniprot id: C6VT17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

471854:DFER RS24640
gene id: 471854:DFER_RS24640
uniprot id: C6W6T6
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS06620
gene id: 471854:DFER_RS06620
uniprot id: C6W6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS23855
gene id: 471854:DFER_RS23855
uniprot id: C6W5Q0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

471854:DFER RS12175
gene id: 471854:DFER_RS12175
uniprot id: C6W0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS25505
gene id: 471854:DFER_RS25505
uniprot id: C6VS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

471854:DFER RS06930
gene id: 471854:DFER_RS06930
uniprot id: C6W743
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

471854:DFER RS21420
gene id: 471854:DFER_RS21420
uniprot id: C6W145
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS26360
gene id: 471854:DFER_RS26360
uniprot id: C6VTB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

471854:DFER RS20360
gene id: 471854:DFER_RS20360
uniprot id: C6VZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS21960
gene id: 471854:DFER_RS21960
uniprot id: C6W234
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS08900
gene id: 471854:DFER_RS08900
uniprot id: C6VUQ6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06805
gene id: 471854:DFER_RS06805
uniprot id: C6W717
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS21265
gene id: 471854:DFER_RS21265
uniprot id: C6W114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS00735
gene id: 471854:DFER_RS00735
uniprot id: C6VVW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

471854:DFER RS22255
gene id: 471854:DFER_RS22255
uniprot id: C6W2V4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

471854:DFER RS27740
gene id: 471854:DFER_RS27740
uniprot id: C6VVL6
names: Similarity
messages: Belongs to the pirin family.

471854:DFER RS07820
gene id: 471854:DFER_RS07820
uniprot id: C6VSK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS05840
gene id: 471854:DFER_RS05840
uniprot id: C6W573
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS14280
gene id: 471854:DFER_RS14280
uniprot id: C6W4K4
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS25030
gene id: 471854:DFER_RS25030
uniprot id: C6W7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

471854:DFER RS18630
gene id: 471854:DFER_RS18630
uniprot id: C6VWC6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

471854:DFER RS05055
gene id: 471854:DFER_RS05055
uniprot id: C6W438
names: Similarity
messages: Belongs to the DSD1 family.

471854:DFER RS14850
gene id: 471854:DFER_RS14850
uniprot id: C6W5K2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18400
gene id: 471854:DFER_RS18400
uniprot id: C6VV91
names: Similarity
messages: Belongs to the UPF0102 family.

471854:DFER RS19075
gene id: 471854:DFER_RS19075
uniprot id: C6VWK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS19470
gene id: 471854:DFER_RS19470
uniprot id: C6VXT5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

471854:DFER RS02010
gene id: 471854:DFER_RS02010
uniprot id: C6VYJ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS04930
gene id: 471854:DFER_RS04930
uniprot id: C6W413
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS12455
gene id: 471854:DFER_RS12455
uniprot id: C6W1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS24480
gene id: 471854:DFER_RS24480
uniprot id: C6W6Q3
names: Similarity
messages: Belongs to the peptidase M16 family.

471854:DFER RS21775
gene id: 471854:DFER_RS21775
uniprot id: C6W1Z8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

471854:DFER RS10095
gene id: 471854:DFER_RS10095
uniprot id: C6VXD1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS22775
gene id: 471854:DFER_RS22775
uniprot id: C6W3S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

471854:DFER RS08410
gene id: 471854:DFER_RS08410
uniprot id: C6VTK3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

471854:DFER RS21390
gene id: 471854:DFER_RS21390
uniprot id: C6W139
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

471854:DFER RS02070
gene id: 471854:DFER_RS02070
uniprot id: C6VZ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

471854:DFER RS11135
gene id: 471854:DFER_RS11135
uniprot id: C6VZK5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS14495
gene id: 471854:DFER_RS14495
uniprot id: C6W5D1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS20645
gene id: 471854:DFER_RS20645
uniprot id: C6W025
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

471854:DFER RS21350
gene id: 471854:DFER_RS21350
uniprot id: C6W131
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS11355
gene id: 471854:DFER_RS11355
uniprot id: C6VZP7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS16955
gene id: 471854:DFER_RS16955
uniprot id: C6VSZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

471854:DFER RS14650
gene id: 471854:DFER_RS14650
uniprot id: C6W5G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

471854:DFER RS12745
gene id: 471854:DFER_RS12745
uniprot id: C6W1R8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

471854:DFER RS18245
gene id: 471854:DFER_RS18245
uniprot id: C6VV61
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

471854:DFER RS10010
gene id: 471854:DFER_RS10010
uniprot id: C6VXB4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS16525
gene id: 471854:DFER_RS16525
uniprot id: C6VS29
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS23125
gene id: 471854:DFER_RS23125
uniprot id: C6W3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

471854:DFER RS04075
gene id: 471854:DFER_RS04075
uniprot id: C6W2B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS00860
gene id: 471854:DFER_RS00860
uniprot id: C6VVZ2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS14670
gene id: 471854:DFER_RS14670
uniprot id: C6W5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

471854:DFER RS15895
gene id: 471854:DFER_RS15895
uniprot id: C6W7E6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471854:DFER RS08405
gene id: 471854:DFER_RS08405
uniprot id: C6VTK2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS12650
gene id: 471854:DFER_RS12650
uniprot id: C6W1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS01965
gene id: 471854:DFER_RS01965
uniprot id: C6VYI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

471854:DFER RS15960
gene id: 471854:DFER_RS15960
uniprot id: C6W7G0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

471854:DFER RS28475
gene id: 471854:DFER_RS28475
uniprot id: C6VXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS04415
gene id: 471854:DFER_RS04415
uniprot id: C6W345
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS10120
gene id: 471854:DFER_RS10120
uniprot id: C6VXD6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS16325
gene id: 471854:DFER_RS16325
uniprot id: C6VRY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS23215
gene id: 471854:DFER_RS23215
uniprot id: C6W4N8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS09940
gene id: 471854:DFER_RS09940
uniprot id: C6VXA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS19625
gene id: 471854:DFER_RS19625
uniprot id: C6VXW7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

471854:DFER RS03820
gene id: 471854:DFER_RS03820
uniprot id: C6W260
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS04165
gene id: 471854:DFER_RS04165
uniprot id: C6W2C3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS27085
gene id: 471854:DFER_RS27085
uniprot id: C6VUE2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18180
gene id: 471854:DFER_RS18180
uniprot id: C6VV48
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS24220
gene id: 471854:DFER_RS24220
uniprot id: C6W5X3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS19250
gene id: 471854:DFER_RS19250
uniprot id: C6VXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

471854:DFER RS16180
gene id: 471854:DFER_RS16180
uniprot id: C6VRV8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

471854:DFER RS24635
gene id: 471854:DFER_RS24635
uniprot id: C6W6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS09845
gene id: 471854:DFER_RS09845
uniprot id: C6VW92
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS07205
gene id: 471854:DFER_RS07205
uniprot id: C6VRK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS25360
gene id: 471854:DFER_RS25360
uniprot id: C6W7U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS28810
gene id: 471854:DFER_RS28810
uniprot id: C6VY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS07895
gene id: 471854:DFER_RS07895
uniprot id: C6VSM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS28425
gene id: 471854:DFER_RS28425
uniprot id: C6VXY3
names: Similarity
messages: Belongs to the TPP enzyme family.

471854:DFER RS14030
gene id: 471854:DFER_RS14030
uniprot id: C6W4F3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

471854:DFER RS16405
gene id: 471854:DFER_RS16405
uniprot id: C6VS04
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS01285
gene id: 471854:DFER_RS01285
uniprot id: C6VX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

471854:DFER RS18480
gene id: 471854:DFER_RS18480
uniprot id: C6VVA7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

471854:DFER RS14480
gene id: 471854:DFER_RS14480
uniprot id: C6W5C8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17705
gene id: 471854:DFER_RS17705
uniprot id: C6VU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS03480
gene id: 471854:DFER_RS03480
uniprot id: C6W1A7
names: Similarity
messages: Belongs to the universal stress protein A family.

471854:DFER RS21120
gene id: 471854:DFER_RS21120
uniprot id: C6W0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

471854:DFER RS28995
gene id: 471854:DFER_RS28995
uniprot id: C6VZF6
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS02570
gene id: 471854:DFER_RS02570
uniprot id: C6VZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS18525
gene id: 471854:DFER_RS18525
uniprot id: C6VVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS16295
gene id: 471854:DFER_RS16295
uniprot id: C6VRY3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

471854:DFER RS01220
gene id: 471854:DFER_RS01220
uniprot id: C6VX47
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS22515
gene id: 471854:DFER_RS22515
uniprot id: C6W309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

471854:DFER RS26265
gene id: 471854:DFER_RS26265
uniprot id: C6VT99
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS00170
gene id: 471854:DFER_RS00170
uniprot id: C6VUJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

471854:DFER RS18340
gene id: 471854:DFER_RS18340
uniprot id: C6VV79
names: Similarity
messages: Belongs to the barstar family.

471854:DFER RS11830
gene id: 471854:DFER_RS11830
uniprot id: C6W0L0
names: Similarity
messages: Belongs to the ribulokinase family.

471854:DFER RS13150
gene id: 471854:DFER_RS13150
uniprot id: C6W2M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS23610
gene id: 471854:DFER_RS23610
uniprot id: C6W4W7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS26785
gene id: 471854:DFER_RS26785
uniprot id: C6VU81
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS15205
gene id: 471854:DFER_RS15205
uniprot id: C6W6E9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

471854:DFER RS20990
gene id: 471854:DFER_RS20990
uniprot id: C6W0W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS18960
gene id: 471854:DFER_RS18960
uniprot id: C6VWI3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS24915
gene id: 471854:DFER_RS24915
uniprot id: C6W7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS16615
gene id: 471854:DFER_RS16615
uniprot id: C6VS47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

471854:DFER RS23480
gene id: 471854:DFER_RS23480
uniprot id: C6W4U2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS05725
gene id: 471854:DFER_RS05725
uniprot id: C6W550
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS16125
gene id: 471854:DFER_RS16125
uniprot id: C6VRV0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

471854:DFER RS24795
gene id: 471854:DFER_RS24795
uniprot id: C6W6W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS14955
gene id: 471854:DFER_RS14955
uniprot id: C6W5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS05615
gene id: 471854:DFER_RS05615
uniprot id: C6W527
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

471854:DFER RS10920
gene id: 471854:DFER_RS10920
uniprot id: C6VYT5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS19595
gene id: 471854:DFER_RS19595
uniprot id: C6VXW0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS23205
gene id: 471854:DFER_RS23205
uniprot id: C6W4N4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

471854:DFER RS21870
gene id: 471854:DFER_RS21870
uniprot id: C6W217
names: Similarity
messages: Belongs to the Skp family.

471854:DFER RS18780
gene id: 471854:DFER_RS18780
uniprot id: C6VWF5
names: Similarity
messages: Belongs to the peptidase S13 family.

471854:DFER RS28400
gene id: 471854:DFER_RS28400
uniprot id: C6VWX9
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

471854:DFER RS23080
gene id: 471854:DFER_RS23080
uniprot id: C6W3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

471854:DFER RS21750
gene id: 471854:DFER_RS21750
uniprot id: C6W1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

471854:DFER RS19385
gene id: 471854:DFER_RS19385
uniprot id: C6VXR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

471854:DFER RS15495
gene id: 471854:DFER_RS15495
uniprot id: C6W6K4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471854:DFER RS13630
gene id: 471854:DFER_RS13630
uniprot id: C6W3J5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

471854:DFER RS14385
gene id: 471854:DFER_RS14385
uniprot id: C6W4M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

471854:DFER RS28295
gene id: 471854:DFER_RS28295
uniprot id: C6VWV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS02875
gene id: 471854:DFER_RS02875
uniprot id: C6W0B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

471854:DFER RS15090
gene id: 471854:DFER_RS15090
uniprot id: C6W6C6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13855
gene id: 471854:DFER_RS13855
uniprot id: C6W4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

471854:DFER RS12450
gene id: 471854:DFER_RS12450
uniprot id: C6W1L0
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS15550
gene id: 471854:DFER_RS15550
uniprot id: C6W6L4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

471854:DFER RS15020
gene id: 471854:DFER_RS15020
uniprot id: C6W6B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS00220
gene id: 471854:DFER_RS00220
uniprot id: C6VUK8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

471854:DFER RS19940
gene id: 471854:DFER_RS19940
uniprot id: C6VZ07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS19590
gene id: 471854:DFER_RS19590
uniprot id: C6VXV9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

471854:DFER RS12790
gene id: 471854:DFER_RS12790
uniprot id: C6W1S7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS08895
gene id: 471854:DFER_RS08895
uniprot id: C6VUQ5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS15805
gene id: 471854:DFER_RS15805
uniprot id: C6W7C7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

471854:DFER RS01080
gene id: 471854:DFER_RS01080
uniprot id: C6VX19
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS16430
gene id: 471854:DFER_RS16430
uniprot id: C6VS09
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

471854:DFER RS27825
gene id: 471854:DFER_RS27825
uniprot id: C6VVN3
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

471854:DFER RS20295
gene id: 471854:DFER_RS20295
uniprot id: C6VZV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

471854:DFER RS18975
gene id: 471854:DFER_RS18975
uniprot id: C6VWI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS17315
gene id: 471854:DFER_RS17315
uniprot id: C6VTT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471854:DFER RS09625
gene id: 471854:DFER_RS09625
uniprot id: C6VW47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

471854:DFER RS21820
gene id: 471854:DFER_RS21820
uniprot id: C6W207
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

471854:DFER RS20570
gene id: 471854:DFER_RS20570
uniprot id: C6W010
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS05145
gene id: 471854:DFER_RS05145
uniprot id: C6W457
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

471854:DFER RS17560
gene id: 471854:DFER_RS17560
uniprot id: C6VTY0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

471854:DFER RS25945
gene id: 471854:DFER_RS25945
uniprot id: C6VSH0
names: Similarity
messages: Belongs to the SCO1/2 family.

471854:DFER RS27655
gene id: 471854:DFER_RS27655
uniprot id: C6VVJ8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS05005
gene id: 471854:DFER_RS05005
uniprot id: C6W428
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

471854:DFER RS21030
gene id: 471854:DFER_RS21030
uniprot id: C6W0X0
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS08140
gene id: 471854:DFER_RS08140
uniprot id: C6VSS1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28150
gene id: 471854:DFER_RS28150
uniprot id: C6VWT0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS19140
gene id: 471854:DFER_RS19140
uniprot id: C6VXL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

471854:DFER RS01875
gene id: 471854:DFER_RS01875
uniprot id: C6VYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

471854:DFER RS28285
gene id: 471854:DFER_RS28285
uniprot id: C6VWV7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

471854:DFER RS05070
gene id: 471854:DFER_RS05070
uniprot id: C6W441
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS05825
gene id: 471854:DFER_RS05825
uniprot id: C6W570
names: Similarity
messages: Belongs to the group II decarboxylase family.

471854:DFER RS11000
gene id: 471854:DFER_RS11000
uniprot id: C6VYV1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS04275
gene id: 471854:DFER_RS04275
uniprot id: C6W2E6
names: Similarity
messages: Belongs to the peptidase C10 family.

471854:DFER RS22950
gene id: 471854:DFER_RS22950
uniprot id: C6W3V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS13830
gene id: 471854:DFER_RS13830
uniprot id: C6W3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

471854:DFER RS19190
gene id: 471854:DFER_RS19190
uniprot id: C6VXM8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

471854:DFER RS21230
gene id: 471854:DFER_RS21230
uniprot id: C6W107
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

471854:DFER RS22065
gene id: 471854:DFER_RS22065
uniprot id: C6W2R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

471854:DFER RS09660
gene id: 471854:DFER_RS09660
uniprot id: C6VW53
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS18860
gene id: 471854:DFER_RS18860
uniprot id: C6VWG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

471854:DFER RS23045
gene id: 471854:DFER_RS23045
uniprot id: C6W3X8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

471854:DFER RS28855
gene id: 471854:DFER_RS28855
uniprot id: C6VY70
names: Similarity
messages: Belongs to the SufE family.

471854:DFER RS02200
gene id: 471854:DFER_RS02200
uniprot id: C6VZA3
names: Similarity
messages: Belongs to the glutamine synthetase family.

471854:DFER RS14465
gene id: 471854:DFER_RS14465
uniprot id: C6W5C4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS00630
gene id: 471854:DFER_RS00630
uniprot id: C6VVU5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

471854:DFER RS20455
gene id: 471854:DFER_RS20455
uniprot id: C6VZY7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

471854:DFER RS26220
gene id: 471854:DFER_RS26220
uniprot id: C6VT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS25350
gene id: 471854:DFER_RS25350
uniprot id: C6W7U5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS06420
gene id: 471854:DFER_RS06420
uniprot id: C6W668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

471854:DFER RS26180
gene id: 471854:DFER_RS26180
uniprot id: C6VT82
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS02275
gene id: 471854:DFER_RS02275
uniprot id: C6VZB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

471854:DFER RS28310
gene id: 471854:DFER_RS28310
uniprot id: C6VWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS11170
gene id: 471854:DFER_RS11170
uniprot id: C6VZL2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS10780
gene id: 471854:DFER_RS10780
uniprot id: C6VYQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS28180
gene id: 471854:DFER_RS28180
uniprot id: C6VWT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

471854:DFER RS21680
gene id: 471854:DFER_RS21680
uniprot id: C6W1X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

471854:DFER RS10865
gene id: 471854:DFER_RS10865
uniprot id: C6VYS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS05960
gene id: 471854:DFER_RS05960
uniprot id: C6W597
names: Subcellular Location Annotation
messages: Mitochondrion

471854:DFER RS00775
gene id: 471854:DFER_RS00775
uniprot id: C6VVX4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS00995
gene id: 471854:DFER_RS00995
uniprot id: C6VX01
names: Similarity
messages: Belongs to the AlaDH/PNT family.

471854:DFER RS00565
gene id: 471854:DFER_RS00565
uniprot id: C6VVT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

471854:DFER RS17090
gene id: 471854:DFER_RS17090
uniprot id: C6VT16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

471854:DFER RS17100
gene id: 471854:DFER_RS17100
uniprot id: C6VT18
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

471854:DFER RS23330
gene id: 471854:DFER_RS23330
uniprot id: C6W4R2
names: Similarity
messages: Belongs to the GroES chaperonin family.

471854:DFER RS22000
gene id: 471854:DFER_RS22000
uniprot id: C6W242
names: Similarity
messages: Belongs to the phosphohexose mutase family.

471854:DFER RS17555
gene id: 471854:DFER_RS17555
uniprot id: C6VTX9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

471854:DFER RS15605
gene id: 471854:DFER_RS15605
uniprot id: C6W787
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

471854:DFER RS20340
gene id: 471854:DFER_RS20340
uniprot id: C6VZW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS19375
gene id: 471854:DFER_RS19375
uniprot id: C6VXR6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

471854:DFER RS12635
gene id: 471854:DFER_RS12635
uniprot id: C6W1P7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS06205
gene id: 471854:DFER_RS06205
uniprot id: C6W626
names: Similarity
messages: Belongs to the DinB family.

471854:DFER RS19430
gene id: 471854:DFER_RS19430
uniprot id: C6VXS7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS03945
gene id: 471854:DFER_RS03945
uniprot id: C6W285
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS01015
gene id: 471854:DFER_RS01015
uniprot id: C6VX05
names: Similarity
messages: Belongs to the ParB family.

471854:DFER RS19390
gene id: 471854:DFER_RS19390
uniprot id: C6VXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

471854:DFER RS19830
gene id: 471854:DFER_RS19830
uniprot id: C6VYY4
names: Similarity
messages: Belongs to the DapA family.

471854:DFER RS06050
gene id: 471854:DFER_RS06050
uniprot id: C6W5Z5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

471854:DFER RS16300
gene id: 471854:DFER_RS16300
uniprot id: C6VRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

471854:DFER RS04505
gene id: 471854:DFER_RS04505
uniprot id: C6W362
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

471854:DFER RS09910
gene id: 471854:DFER_RS09910
uniprot id: C6VWA5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS26775
gene id: 471854:DFER_RS26775
uniprot id: C6VU79
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

471854:DFER RS16115
gene id: 471854:DFER_RS16115
uniprot id: C6W7J1
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

471854:DFER RS19050
gene id: 471854:DFER_RS19050
uniprot id: C6VWK2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS06995
gene id: 471854:DFER_RS06995
uniprot id: C6W757
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

471854:DFER RS19510
gene id: 471854:DFER_RS19510
uniprot id: C6VXU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS12730
gene id: 471854:DFER_RS12730
uniprot id: C6W1R5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

471854:DFER RS26600
gene id: 471854:DFER_RS26600
uniprot id: C6VTG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

471854:DFER RS16720
gene id: 471854:DFER_RS16720
uniprot id: C6VSU3
names: Similarity
messages: Belongs to the pyruvate kinase family.

471854:DFER RS22005
gene id: 471854:DFER_RS22005
uniprot id: C6W243
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

471854:DFER RS23935
gene id: 471854:DFER_RS23935
uniprot id: C6W5R6
names: Similarity
messages: Belongs to the FGGY kinase family.

471854:DFER RS00305
gene id: 471854:DFER_RS00305
uniprot id: C6VUM4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS03205
gene id: 471854:DFER_RS03205
uniprot id: C6W153
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

471854:DFER RS01180
gene id: 471854:DFER_RS01180
uniprot id: C6VX39
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

471854:DFER RS19715
gene id: 471854:DFER_RS19715
uniprot id: C6VYW2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS25825
gene id: 471854:DFER_RS25825
uniprot id: C6VSE7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

471854:DFER RS21585
gene id: 471854:DFER_RS21585
uniprot id: C6W1V8
names: Similarity
messages: Belongs to the peptidase M13 family.

471854:DFER RS12565
gene id: 471854:DFER_RS12565
uniprot id: C6W1N3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS09760
gene id: 471854:DFER_RS09760
uniprot id: C6VW74
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

471854:DFER RS10330
gene id: 471854:DFER_RS10330
uniprot id: C6VXH8
names: Similarity
messages: Belongs to the peptidase U62 family.

471854:DFER RS25305
gene id: 471854:DFER_RS25305
uniprot id: C6W7T6
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

471854:DFER RS15420
gene id: 471854:DFER_RS15420
uniprot id: C6W6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

471854:DFER RS03925
gene id: 471854:DFER_RS03925
uniprot id: C6W281
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS02340
gene id: 471854:DFER_RS02340
uniprot id: C6VZD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

471854:DFER RS16715
gene id: 471854:DFER_RS16715
uniprot id: C6VSU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

471854:DFER RS09680
gene id: 471854:DFER_RS09680
uniprot id: C6VW57
names: Similarity
messages: Belongs to the peptidase M1 family.

471854:DFER RS18720
gene id: 471854:DFER_RS18720
uniprot id: C6VWE3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS10285
gene id: 471854:DFER_RS10285
uniprot id: C6VXG9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS26520
gene id: 471854:DFER_RS26520
uniprot id: C6VTE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS13935
gene id: 471854:DFER_RS13935
uniprot id: C6W4D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS05160
gene id: 471854:DFER_RS05160
uniprot id: C6W460
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

471854:DFER RS18510
gene id: 471854:DFER_RS18510
uniprot id: C6VVB2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

471854:DFER RS19410
gene id: 471854:DFER_RS19410
uniprot id: C6VXS3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS15860
gene id: 471854:DFER_RS15860
uniprot id: C6W7D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

471854:DFER RS10925
gene id: 471854:DFER_RS10925
uniprot id: C6VYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS21635
gene id: 471854:DFER_RS21635
uniprot id: C6W1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

471854:DFER RS23240
gene id: 471854:DFER_RS23240
uniprot id: C6W4P4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

471854:DFER RS03930
gene id: 471854:DFER_RS03930
uniprot id: C6W282
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS11150
gene id: 471854:DFER_RS11150
uniprot id: C6VZK8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS17050
gene id: 471854:DFER_RS17050
uniprot id: C6VT08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

471854:DFER RS20320
gene id: 471854:DFER_RS20320
uniprot id: C6VZV9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

471854:DFER RS23285
gene id: 471854:DFER_RS23285
uniprot id: C6W4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

471854:DFER RS17665
gene id: 471854:DFER_RS17665
uniprot id: C6VU01
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

471854:DFER RS12375
gene id: 471854:DFER_RS12375
uniprot id: C6W1J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

471854:DFER RS21765
gene id: 471854:DFER_RS21765
uniprot id: C6W1Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

471854:DFER RS12960
gene id: 471854:DFER_RS12960
uniprot id: C6W2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS23560
gene id: 471854:DFER_RS23560
uniprot id: C6W4V8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

471854:DFER RS16930
gene id: 471854:DFER_RS16930
uniprot id: C6VSY6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS16090
gene id: 471854:DFER_RS16090
uniprot id: C6W7I6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

471854:DFER RS13920
gene id: 471854:DFER_RS13920
uniprot id: C6W4D0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

471854:DFER RS22220
gene id: 471854:DFER_RS22220
uniprot id: C6W2U7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

471854:DFER RS19850
gene id: 471854:DFER_RS19850
uniprot id: C6VYY8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17075
gene id: 471854:DFER_RS17075
uniprot id: C6VT13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

471854:DFER RS17600
gene id: 471854:DFER_RS17600
uniprot id: C6VTY8
names: Similarity
messages: Belongs to the BshC family.

471854:DFER RS28715
gene id: 471854:DFER_RS28715
uniprot id: C6VY42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS23555
gene id: 471854:DFER_RS23555
uniprot id: C6W4V7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS06025
gene id: 471854:DFER_RS06025
uniprot id: C6W5Z0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS13175
gene id: 471854:DFER_RS13175
uniprot id: C6W2N0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

471854:DFER RS17605
gene id: 471854:DFER_RS17605
uniprot id: C6VTY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471854:DFER RS12855
gene id: 471854:DFER_RS12855
uniprot id: C6W2G6
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS07085
gene id: 471854:DFER_RS07085
uniprot id: C6W775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS19270
gene id: 471854:DFER_RS19270
uniprot id: C6VXP4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471854:DFER RS24150
gene id: 471854:DFER_RS24150
uniprot id: C6W5V9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17990
gene id: 471854:DFER_RS17990
uniprot id: C6VV10
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

471854:DFER RS20170
gene id: 471854:DFER_RS20170
uniprot id: C6VZ51
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

471854:DFER RS12540
gene id: 471854:DFER_RS12540
uniprot id: C6W1M8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

471854:DFER RS24205
gene id: 471854:DFER_RS24205
uniprot id: C6W5X0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS10665
gene id: 471854:DFER_RS10665
uniprot id: C6VYN4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS21530
gene id: 471854:DFER_RS21530
uniprot id: C6W1U7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

471854:DFER RS13910
gene id: 471854:DFER_RS13910
uniprot id: C6W4C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

471854:DFER RS18690
gene id: 471854:DFER_RS18690
uniprot id: C6VWD7
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

471854:DFER RS18475
gene id: 471854:DFER_RS18475
uniprot id: C6VVA6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS18005
gene id: 471854:DFER_RS18005
uniprot id: C6VV13
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

471854:DFER RS13700
gene id: 471854:DFER_RS13700
uniprot id: C6W3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

471854:DFER RS14805
gene id: 471854:DFER_RS14805
uniprot id: C6W5J3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

471854:DFER RS09830
gene id: 471854:DFER_RS09830
uniprot id: C6VW88
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471854:DFER RS28155
gene id: 471854:DFER_RS28155
uniprot id: C6VWT1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS22800
gene id: 471854:DFER_RS22800
uniprot id: C6W3T1
names: Similarity
messages: Belongs to the Fur family.

471854:DFER RS14735
gene id: 471854:DFER_RS14735
uniprot id: C6W5H9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS23085
gene id: 471854:DFER_RS23085
uniprot id: C6W3Y6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

471854:DFER RS20325
gene id: 471854:DFER_RS20325
uniprot id: C6VZW0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

471854:DFER RS28610
gene id: 471854:DFER_RS28610
uniprot id: C6VY21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS02150
gene id: 471854:DFER_RS02150
uniprot id: C6VZ93
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

471854:DFER RS06175
gene id: 471854:DFER_RS06175
uniprot id: C6W619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

471854:DFER RS27185
gene id: 471854:DFER_RS27185
uniprot id: C6VUG2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS30320
gene id: 471854:DFER_RS30320
uniprot id: C6W179
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

471854:DFER RS03765
gene id: 471854:DFER_RS03765
uniprot id: C6W248
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

471854:DFER RS24655
gene id: 471854:DFER_RS24655
uniprot id: C6W6T9
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS09100
gene id: 471854:DFER_RS09100
uniprot id: C6VUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS29320
gene id: 471854:DFER_RS29320
uniprot id: C6W3W2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS19340
gene id: 471854:DFER_RS19340
uniprot id: C6VXQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

471854:DFER RS20185
gene id: 471854:DFER_RS20185
uniprot id: C6VZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

471854:DFER RS22235
gene id: 471854:DFER_RS22235
uniprot id: C6W2V0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

471854:DFER RS25570
gene id: 471854:DFER_RS25570
uniprot id: C6VS97
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471854:DFER RS11745
gene id: 471854:DFER_RS11745
uniprot id: C6W0J2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

471854:DFER RS06215
gene id: 471854:DFER_RS06215
uniprot id: C6W628
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17540
gene id: 471854:DFER_RS17540
uniprot id: C6VTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

471854:DFER RS16830
gene id: 471854:DFER_RS16830
uniprot id: C6VSW5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

471854:DFER RS07000
gene id: 471854:DFER_RS07000
uniprot id: C6W758
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS10375
gene id: 471854:DFER_RS10375
uniprot id: C6VXI7
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

471854:DFER RS17260
gene id: 471854:DFER_RS17260
uniprot id: C6VT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

471854:DFER RS02955
gene id: 471854:DFER_RS02955
uniprot id: C6W0C5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

471854:DFER RS13905
gene id: 471854:DFER_RS13905
uniprot id: C6W4C7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

471854:DFER RS18515
gene id: 471854:DFER_RS18515
uniprot id: C6VVB3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

471854:DFER RS28840
gene id: 471854:DFER_RS28840
uniprot id: C6VY67
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

471854:DFER RS22345
gene id: 471854:DFER_RS22345
uniprot id: C6W2X5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

471854:DFER RS03720
gene id: 471854:DFER_RS03720
uniprot id: C6W1F5
names: Similarity
messages: Belongs to the ketopantoate reductase family.

471854:DFER RS22650
gene id: 471854:DFER_RS22650
uniprot id: C6W3Q2
names: Similarity
messages: Belongs to the ComB family.

471854:DFER RS01570
gene id: 471854:DFER_RS01570
uniprot id: C6VYA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

471854:DFER RS23545
gene id: 471854:DFER_RS23545
uniprot id: C6W4V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS19040
gene id: 471854:DFER_RS19040
uniprot id: C6VWK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

471854:DFER RS15885
gene id: 471854:DFER_RS15885
uniprot id: C6W7E3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

471854:DFER RS20640
gene id: 471854:DFER_RS20640
uniprot id: C6W024
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

471854:DFER RS17400
gene id: 471854:DFER_RS17400
uniprot id: C6VTV0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

471854:DFER RS26040
gene id: 471854:DFER_RS26040
uniprot id: C6VT61
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

471854:DFER RS06860
gene id: 471854:DFER_RS06860
uniprot id: C6W728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS17340
gene id: 471854:DFER_RS17340
uniprot id: C6VTT8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

471854:DFER RS27960
gene id: 471854:DFER_RS27960
uniprot id: C6VWP0
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS18520
gene id: 471854:DFER_RS18520
uniprot id: C6VVB4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS11055
gene id: 471854:DFER_RS11055
uniprot id: C6VZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS15775
gene id: 471854:DFER_RS15775
uniprot id: C6W7C1
names: Similarity
messages: Belongs to the type IB topoisomerase family.

471854:DFER RS07190
gene id: 471854:DFER_RS07190
uniprot id: C6VRK2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS20310
gene id: 471854:DFER_RS20310
uniprot id: C6VZV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

471854:DFER RS07090
gene id: 471854:DFER_RS07090
uniprot id: C6W776
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS03395
gene id: 471854:DFER_RS03395
uniprot id: C6W190
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS08780
gene id: 471854:DFER_RS08780
uniprot id: C6VTS7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS16130
gene id: 471854:DFER_RS16130
uniprot id: C6VRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

471854:DFER RS25060
gene id: 471854:DFER_RS25060
uniprot id: C6W7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

471854:DFER RS01075
gene id: 471854:DFER_RS01075
uniprot id: C6VX18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS11855
gene id: 471854:DFER_RS11855
uniprot id: C6W0L5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS24155
gene id: 471854:DFER_RS24155
uniprot id: C6W5W0
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13335
gene id: 471854:DFER_RS13335
uniprot id: C6W3D6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

471854:DFER RS16265
gene id: 471854:DFER_RS16265
uniprot id: C6VRX7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS21175
gene id: 471854:DFER_RS21175
uniprot id: C6W0Z6
names: Similarity
messages: Belongs to the DNA photolyase family.

471854:DFER RS09790
gene id: 471854:DFER_RS09790
uniprot id: C6VW80
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471854:DFER RS13010
gene id: 471854:DFER_RS13010
uniprot id: C6W2J7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS20275
gene id: 471854:DFER_RS20275
uniprot id: C6VZV0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

471854:DFER RS17455
gene id: 471854:DFER_RS17455
uniprot id: C6VTW0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS13995
gene id: 471854:DFER_RS13995
uniprot id: C6W4E6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS28375
gene id: 471854:DFER_RS28375
uniprot id: C6VWX4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

471854:DFER RS19765
gene id: 471854:DFER_RS19765
uniprot id: C6VYX1
names: Similarity
messages: Belongs to the Skp family.

471854:DFER RS05275
gene id: 471854:DFER_RS05275
uniprot id: C6W482
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS02430
gene id: 471854:DFER_RS02430
uniprot id: C6VZE8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS07515
gene id: 471854:DFER_RS07515
uniprot id: C6VRR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

471854:DFER RS05210
gene id: 471854:DFER_RS05210
uniprot id: C6W470
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

471854:DFER RS17155
gene id: 471854:DFER_RS17155
uniprot id: C6VT25
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

471854:DFER RS19480
gene id: 471854:DFER_RS19480
uniprot id: C6VXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

471854:DFER RS09630
gene id: 471854:DFER_RS09630
uniprot id: C6VW48
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

471854:DFER RS21700
gene id: 471854:DFER_RS21700
uniprot id: C6W1Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

471854:DFER RS27750
gene id: 471854:DFER_RS27750
uniprot id: C6VVL8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

471854:DFER RS25815
gene id: 471854:DFER_RS25815
uniprot id: C6VSE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

471854:DFER RS13715
gene id: 471854:DFER_RS13715
uniprot id: C6W3L2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS14905
gene id: 471854:DFER_RS14905
uniprot id: C6W5L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

471854:DFER RS03365
gene id: 471854:DFER_RS03365
uniprot id: C6W184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS28170
gene id: 471854:DFER_RS28170
uniprot id: C6VWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

471854:DFER RS11025
gene id: 471854:DFER_RS11025
uniprot id: C6VYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS09255
gene id: 471854:DFER_RS09255
uniprot id: C6VUX5
names: Similarity
messages: Belongs to the peptidase S33 family.

471854:DFER RS13410
gene id: 471854:DFER_RS13410
uniprot id: C6W3F0
names: Similarity
messages: Belongs to the peptidase S66 family.

471854:DFER RS01025
gene id: 471854:DFER_RS01025
uniprot id: C6VX07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

471854:DFER RS01960
gene id: 471854:DFER_RS01960
uniprot id: C6VYI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

471854:DFER RS13845
gene id: 471854:DFER_RS13845
uniprot id: C6W3N8
names: Similarity
messages: Belongs to the peptidase S49 family.

471854:DFER RS03455
gene id: 471854:DFER_RS03455
uniprot id: C6W1A2
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18270
gene id: 471854:DFER_RS18270
uniprot id: C6VV66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS14825
gene id: 471854:DFER_RS14825
uniprot id: C6W5J7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

471854:DFER RS05215
gene id: 471854:DFER_RS05215
uniprot id: C6W471
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS09885
gene id: 471854:DFER_RS09885
uniprot id: C6VWA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

471854:DFER RS07485
gene id: 471854:DFER_RS07485
uniprot id: C6VRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS20655
gene id: 471854:DFER_RS20655
uniprot id: C6W027
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

471854:DFER RS21275
gene id: 471854:DFER_RS21275
uniprot id: C6W116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS00145
gene id: 471854:DFER_RS00145
uniprot id: C6VUJ3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS12500
gene id: 471854:DFER_RS12500
uniprot id: C6W1M0
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS10420
gene id: 471854:DFER_RS10420
uniprot id: C6VXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS17885
gene id: 471854:DFER_RS17885
uniprot id: C6VU44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

471854:DFER RS02745
gene id: 471854:DFER_RS02745
uniprot id: C6W086
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

471854:DFER RS22760
gene id: 471854:DFER_RS22760
uniprot id: C6W3S4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

471854:DFER RS02135
gene id: 471854:DFER_RS02135
uniprot id: C6VZ90
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS26900
gene id: 471854:DFER_RS26900
uniprot id: C6VUA5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

471854:DFER RS21705
gene id: 471854:DFER_RS21705
uniprot id: C6W1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

471854:DFER RS16730
gene id: 471854:DFER_RS16730
uniprot id: C6VSU5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

471854:DFER RS22795
gene id: 471854:DFER_RS22795
uniprot id: C6W3T0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

471854:DFER RS27245
gene id: 471854:DFER_RS27245
uniprot id: C6VVC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS11065
gene id: 471854:DFER_RS11065
uniprot id: C6VZJ1
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28735
gene id: 471854:DFER_RS28735
uniprot id: C6VY46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

471854:DFER RS11450
gene id: 471854:DFER_RS11450
uniprot id: C6VZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

471854:DFER RS18875
gene id: 471854:DFER_RS18875
uniprot id: C6VWH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

471854:DFER RS13090
gene id: 471854:DFER_RS13090
uniprot id: C6W2L3
names: Similarity
messages: Belongs to the UPF0145 family.

471854:DFER RS24045
gene id: 471854:DFER_RS24045
uniprot id: C6W5T8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

471854:DFER RS14440
gene id: 471854:DFER_RS14440
uniprot id: C6W5B9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS24445
gene id: 471854:DFER_RS24445
uniprot id: C6W6P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS01215
gene id: 471854:DFER_RS01215
uniprot id: C6VX46
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

471854:DFER RS07670
gene id: 471854:DFER_RS07670
uniprot id: C6VRU8
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS17630
gene id: 471854:DFER_RS17630
uniprot id: C6VTZ4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13215
gene id: 471854:DFER_RS13215
uniprot id: C6W2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

471854:DFER RS00475
gene id: 471854:DFER_RS00475
uniprot id: C6VVR3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

471854:DFER RS20520
gene id: 471854:DFER_RS20520
uniprot id: C6W000
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

471854:DFER RS04150
gene id: 471854:DFER_RS04150
uniprot id: C6W2C0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

471854:DFER RS20650
gene id: 471854:DFER_RS20650
uniprot id: C6W026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

471854:DFER RS22690
gene id: 471854:DFER_RS22690
uniprot id: C6W3R0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

471854:DFER RS18080
gene id: 471854:DFER_RS18080
uniprot id: C6VV28
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

471854:DFER RS23565
gene id: 471854:DFER_RS23565
uniprot id: C6W4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

471854:DFER RS05030
gene id: 471854:DFER_RS05030
uniprot id: C6W433
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

471854:DFER RS15955
gene id: 471854:DFER_RS15955
uniprot id: C6W7F9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

471854:DFER RS04590
gene id: 471854:DFER_RS04590
uniprot id: C6W379
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

471854:DFER RS21625
gene id: 471854:DFER_RS21625
uniprot id: C6W1W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

471854:DFER RS01060
gene id: 471854:DFER_RS01060
uniprot id: C6VX15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

471854:DFER RS11985
gene id: 471854:DFER_RS11985
uniprot id: C6W0P2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

471854:DFER RS08705
gene id: 471854:DFER_RS08705
uniprot id: C6VTR3
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS23870
gene id: 471854:DFER_RS23870
uniprot id: C6W5Q3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

471854:DFER RS03390
gene id: 471854:DFER_RS03390
uniprot id: C6W189
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS08830
gene id: 471854:DFER_RS08830
uniprot id: C6VUP2
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS14070
gene id: 471854:DFER_RS14070
uniprot id: C6W4G1
names: Similarity
messages: Belongs to the peptidase M17 family.

471854:DFER RS29230
gene id: 471854:DFER_RS29230
uniprot id: C6W0S2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS18225
gene id: 471854:DFER_RS18225
uniprot id: C6VV57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

471854:DFER RS08755
gene id: 471854:DFER_RS08755
uniprot id: C6VTS3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS16735
gene id: 471854:DFER_RS16735
uniprot id: C6VSU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

471854:DFER RS20705
gene id: 471854:DFER_RS20705
uniprot id: C6W038
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

471854:DFER RS17985
gene id: 471854:DFER_RS17985
uniprot id: C6VV09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

471854:DFER RS22745
gene id: 471854:DFER_RS22745
uniprot id: C6W3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS09120
gene id: 471854:DFER_RS09120
uniprot id: C6VUU9
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS04005
gene id: 471854:DFER_RS04005
uniprot id: C6W297
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS09160
gene id: 471854:DFER_RS09160
uniprot id: C6VUV7
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS13585
gene id: 471854:DFER_RS13585
uniprot id: C6W3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

471854:DFER RS10085
gene id: 471854:DFER_RS10085
uniprot id: C6VXC9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS02105
gene id: 471854:DFER_RS02105
uniprot id: C6VZ84
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS13325
gene id: 471854:DFER_RS13325
uniprot id: C6W2Q8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

471854:DFER RS05205
gene id: 471854:DFER_RS05205
uniprot id: C6W469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

471854:DFER RS21900
gene id: 471854:DFER_RS21900
uniprot id: C6W223
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

471854:DFER RS23790
gene id: 471854:DFER_RS23790
uniprot id: C6W5N7
names: Subcellular Location Annotation
messages: Nucleus

471854:DFER RS20390
gene id: 471854:DFER_RS20390
uniprot id: C6VZX3
names: Similarity
messages: Belongs to the DEAD box helicase family.

471854:DFER RS28520
gene id: 471854:DFER_RS28520
uniprot id: C6VY02
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS02565
gene id: 471854:DFER_RS02565
uniprot id: C6VZH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS20220
gene id: 471854:DFER_RS20220
uniprot id: C6VZ61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

471854:DFER RS27330
gene id: 471854:DFER_RS27330
uniprot id: C6VVE2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

471854:DFER RS22225
gene id: 471854:DFER_RS22225
uniprot id: C6W2U8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17910
gene id: 471854:DFER_RS17910
uniprot id: C6VU50
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

471854:DFER RS13165
gene id: 471854:DFER_RS13165
uniprot id: C6W2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

471854:DFER RS19845
gene id: 471854:DFER_RS19845
uniprot id: C6VYY7
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS05980
gene id: 471854:DFER_RS05980
uniprot id: C6W5A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

471854:DFER RS26755
gene id: 471854:DFER_RS26755
uniprot id: C6VU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS16640
gene id: 471854:DFER_RS16640
uniprot id: C6VS52
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS20100
gene id: 471854:DFER_RS20100
uniprot id: C6VZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

471854:DFER RS15545
gene id: 471854:DFER_RS15545
uniprot id: C6W6L3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS24850
gene id: 471854:DFER_RS24850
uniprot id: C6W7J4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

471854:DFER RS21575
gene id: 471854:DFER_RS21575
uniprot id: C6W1V6
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS12220
gene id: 471854:DFER_RS12220
uniprot id: C6W1G4
names: Similarity
messages: Belongs to the CarB family.

471854:DFER RS06510
gene id: 471854:DFER_RS06510
uniprot id: C6W688
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS25500
gene id: 471854:DFER_RS25500
uniprot id: C6VS83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

471854:DFER RS05195
gene id: 471854:DFER_RS05195
uniprot id: C6W467
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

471854:DFER RS21000
gene id: 471854:DFER_RS21000
uniprot id: C6W0W5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

471854:DFER RS15725
gene id: 471854:DFER_RS15725
uniprot id: C6W7B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

471854:DFER RS13380
gene id: 471854:DFER_RS13380
uniprot id: C6W3E5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

471854:DFER RS26215
gene id: 471854:DFER_RS26215
uniprot id: C6VT89
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS07475
gene id: 471854:DFER_RS07475
uniprot id: C6VRQ8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS21190
gene id: 471854:DFER_RS21190
uniprot id: C6W0Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS00215
gene id: 471854:DFER_RS00215
uniprot id: C6VUK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

471854:DFER RS24535
gene id: 471854:DFER_RS24535
uniprot id: C6W6R3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

471854:DFER RS10150
gene id: 471854:DFER_RS10150
uniprot id: C6VXE2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

471854:DFER RS28805
gene id: 471854:DFER_RS28805
uniprot id: C6VY60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

471854:DFER RS27730
gene id: 471854:DFER_RS27730
uniprot id: C6VVL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

471854:DFER RS22120
gene id: 471854:DFER_RS22120
uniprot id: C6W2S7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

471854:DFER RS24200
gene id: 471854:DFER_RS24200
uniprot id: C6W5W9
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS13245
gene id: 471854:DFER_RS13245
uniprot id: C6W2P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

471854:DFER RS23385
gene id: 471854:DFER_RS23385
uniprot id: C6W4S3
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS19465
gene id: 471854:DFER_RS19465
uniprot id: C6VXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

471854:DFER RS00430
gene id: 471854:DFER_RS00430
uniprot id: C6VVQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS00330
gene id: 471854:DFER_RS00330
uniprot id: C6VUM9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

471854:DFER RS27255
gene id: 471854:DFER_RS27255
uniprot id: C6VVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

471854:DFER RS00820
gene id: 471854:DFER_RS00820
uniprot id: C6VVY4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS01155
gene id: 471854:DFER_RS01155
uniprot id: C6VX34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

471854:DFER RS20770
gene id: 471854:DFER_RS20770
uniprot id: C6W050
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

471854:DFER RS15890
gene id: 471854:DFER_RS15890
uniprot id: C6W7E5
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

471854:DFER RS00420
gene id: 471854:DFER_RS00420
uniprot id: C6VVQ1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

471854:DFER RS08905
gene id: 471854:DFER_RS08905
uniprot id: C6VUQ8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS14830
gene id: 471854:DFER_RS14830
uniprot id: C6W5J8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

471854:DFER RS01145
gene id: 471854:DFER_RS01145
uniprot id: C6VX32
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471854:DFER RS10370
gene id: 471854:DFER_RS10370
uniprot id: C6VXI6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

471854:DFER RS22370
gene id: 471854:DFER_RS22370
uniprot id: C6W2Y0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

471854:DFER RS08980
gene id: 471854:DFER_RS08980
uniprot id: C6VUS3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS21115
gene id: 471854:DFER_RS21115
uniprot id: C6W0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

471854:DFER RS29090
gene id: 471854:DFER_RS29090
uniprot id: C6W705
names: Similarity
messages: In the C-terminal section; belongs to the bacterial STING family.

471854:DFER RS01410
gene id: 471854:DFER_RS01410
uniprot id: C6VX84
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

471854:DFER RS03170
gene id: 471854:DFER_RS03170
uniprot id: C6W0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS00965
gene id: 471854:DFER_RS00965
uniprot id: C6VWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

471854:DFER RS17900
gene id: 471854:DFER_RS17900
uniprot id: C6VU48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

471854:DFER RS23820
gene id: 471854:DFER_RS23820
uniprot id: C6W5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS21720
gene id: 471854:DFER_RS21720
uniprot id: C6W1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

471854:DFER RS23570
gene id: 471854:DFER_RS23570
uniprot id: C6W4W0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

471854:DFER RS28625
gene id: 471854:DFER_RS28625
uniprot id: C6VY24
names: Similarity
messages: Belongs to the UxaA family.

471854:DFER RS25335
gene id: 471854:DFER_RS25335
uniprot id: C6W7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

471854:DFER RS13940
gene id: 471854:DFER_RS13940
uniprot id: C6W4D4
names: Similarity
messages: Belongs to the aldose epimerase family.

471854:DFER RS28070
gene id: 471854:DFER_RS28070
uniprot id: C6VWR4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

471854:DFER RS19060
gene id: 471854:DFER_RS19060
uniprot id: C6VWK4
names: Similarity
messages: Belongs to the MreC family.

471854:DFER RS01160
gene id: 471854:DFER_RS01160
uniprot id: C6VX35
names: Similarity
messages: Belongs to the Nudix hydrolase family.

471854:DFER RS09110
gene id: 471854:DFER_RS09110
uniprot id: C6VUU7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS27815
gene id: 471854:DFER_RS27815
uniprot id: C6VVN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS00225
gene id: 471854:DFER_RS00225
uniprot id: C6VUK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

471854:DFER RS20175
gene id: 471854:DFER_RS20175
uniprot id: C6VZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

471854:DFER RS28320
gene id: 471854:DFER_RS28320
uniprot id: C6VWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS10520
gene id: 471854:DFER_RS10520
uniprot id: C6VYK4
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS15345
gene id: 471854:DFER_RS15345
uniprot id: C6W6H7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

471854:DFER RS18095
gene id: 471854:DFER_RS18095
uniprot id: C6VV31
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

471854:DFER RS20405
gene id: 471854:DFER_RS20405
uniprot id: C6VZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS06865
gene id: 471854:DFER_RS06865
uniprot id: C6W729
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

471854:DFER RS17940
gene id: 471854:DFER_RS17940
uniprot id: C6VV00
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS28110
gene id: 471854:DFER_RS28110
uniprot id: C6VWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

471854:DFER RS20795
gene id: 471854:DFER_RS20795
uniprot id: C6W055
names: Similarity
messages: Belongs to the peptidase C40 family.

471854:DFER RS17715
gene id: 471854:DFER_RS17715
uniprot id: C6VU11
names: Similarity
messages: Belongs to the peptidase S58 family.

471854:DFER RS16860
gene id: 471854:DFER_RS16860
uniprot id: C6VSX2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

471854:DFER RS11340
gene id: 471854:DFER_RS11340
uniprot id: C6VZP4
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS24905
gene id: 471854:DFER_RS24905
uniprot id: C6W7K6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

471854:DFER RS13775
gene id: 471854:DFER_RS13775
uniprot id: C6W3M4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

471854:DFER RS15750
gene id: 471854:DFER_RS15750
uniprot id: C6W7B6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

471854:DFER RS28200
gene id: 471854:DFER_RS28200
uniprot id: C6VWU0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

471854:DFER RS02065
gene id: 471854:DFER_RS02065
uniprot id: C6VZ76
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471854:DFER RS28680
gene id: 471854:DFER_RS28680
uniprot id: C6VY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

471854:DFER RS19730
gene id: 471854:DFER_RS19730
uniprot id: C6VYW4
names: Similarity
messages: Belongs to the fabD family.

471854:DFER RS00690
gene id: 471854:DFER_RS00690
uniprot id: C6VVV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

471854:DFER RS28040
gene id: 471854:DFER_RS28040
uniprot id: C6VWQ6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

471854:DFER RS22015
gene id: 471854:DFER_RS22015
uniprot id: C6W245
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

471854:DFER RS03715
gene id: 471854:DFER_RS03715
uniprot id: C6W1F4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

471854:DFER RS11155
gene id: 471854:DFER_RS11155
uniprot id: C6VZK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS23700
gene id: 471854:DFER_RS23700
uniprot id: C6W4Y4
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS18300
gene id: 471854:DFER_RS18300
uniprot id: C6VV72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

471854:DFER RS28335
gene id: 471854:DFER_RS28335
uniprot id: C6VWW7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

471854:DFER RS06035
gene id: 471854:DFER_RS06035
uniprot id: C6W5Z2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

471854:DFER RS06435
gene id: 471854:DFER_RS06435
uniprot id: C6W672
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

471854:DFER RS17180
gene id: 471854:DFER_RS17180
uniprot id: C6VT30
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS24920
gene id: 471854:DFER_RS24920
uniprot id: C6W7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

471854:DFER RS24660
gene id: 471854:DFER_RS24660
uniprot id: C6W6U0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

471854:DFER RS02810
gene id: 471854:DFER_RS02810
uniprot id: C6W098
names: Similarity
messages: Belongs to the YciI family.

471854:DFER RS22400
gene id: 471854:DFER_RS22400
uniprot id: C6W2Y5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS16740
gene id: 471854:DFER_RS16740
uniprot id: C6VSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

471854:DFER RS24785
gene id: 471854:DFER_RS24785
uniprot id: C6W6W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

471854:DFER RS23520
gene id: 471854:DFER_RS23520
uniprot id: C6W4V0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

471854:DFER RS21310
gene id: 471854:DFER_RS21310
uniprot id: C6W123
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS06230
gene id: 471854:DFER_RS06230
uniprot id: C6W631
names: Similarity
messages: Belongs to the UPF0047 family.

471854:DFER RS03000
gene id: 471854:DFER_RS03000
uniprot id: C6W0D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

471854:DFER RS16780
gene id: 471854:DFER_RS16780
uniprot id: C6VSV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

471854:DFER RS09645
gene id: 471854:DFER_RS09645
uniprot id: C6VW51
names: Similarity
messages: Belongs to the DinB family.

471854:DFER RS00495
gene id: 471854:DFER_RS00495
uniprot id: C6VVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS13970
gene id: 471854:DFER_RS13970
uniprot id: C6W4E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

471854:DFER RS17515
gene id: 471854:DFER_RS17515
uniprot id: C6VTX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

471854:DFER RS23495
gene id: 471854:DFER_RS23495
uniprot id: C6W4U5
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS13625
gene id: 471854:DFER_RS13625
uniprot id: C6W3J4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

471854:DFER RS06165
gene id: 471854:DFER_RS06165
uniprot id: C6W617
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

471854:DFER RS21785
gene id: 471854:DFER_RS21785
uniprot id: C6W200
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

471854:DFER RS09805
gene id: 471854:DFER_RS09805
uniprot id: C6VW83
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

471854:DFER RS09720
gene id: 471854:DFER_RS09720
uniprot id: C6VW66
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

471854:DFER RS16345
gene id: 471854:DFER_RS16345
uniprot id: C6VRZ3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

471854:DFER RS25630
gene id: 471854:DFER_RS25630
uniprot id: C6VSA9
names: Similarity
messages: Belongs to the UPF0758 family.

471854:DFER RS10540
gene id: 471854:DFER_RS10540
uniprot id: C6VYK8
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS08685
gene id: 471854:DFER_RS08685
uniprot id: C6VTQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS23030
gene id: 471854:DFER_RS23030
uniprot id: C6W3X5
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS05345
gene id: 471854:DFER_RS05345
uniprot id: C6W496
names: Similarity
messages: Belongs to the AHA1 family.

471854:DFER RS22680
gene id: 471854:DFER_RS22680
uniprot id: C6W3Q8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

471854:DFER RS05415
gene id: 471854:DFER_RS05415
uniprot id: C6W4B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

471854:DFER RS02040
gene id: 471854:DFER_RS02040
uniprot id: C6VYK3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS17300
gene id: 471854:DFER_RS17300
uniprot id: C6VTT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

471854:DFER RS24020
gene id: 471854:DFER_RS24020
uniprot id: C6W5T3
names: Subcellular Location Annotation
messages: Membrane

471854:DFER RS22280
gene id: 471854:DFER_RS22280
uniprot id: C6W2V9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

471854:DFER RS13160
gene id: 471854:DFER_RS13160
uniprot id: C6W2M7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

471854:DFER RS23345
gene id: 471854:DFER_RS23345
uniprot id: C6W4R5
names: Subcellular Location Annotation
messages: Cytoplasm

471854:DFER RS08125
gene id: 471854:DFER_RS08125
uniprot id: C6VSR8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

471854:DFER RS18335
gene id: 471854:DFER_RS18335
uniprot id: C6VV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

471854:DFER RS23740
gene id: 471854:DFER_RS23740
uniprot id: C6W5M7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

471854:DFER RS04990
gene id: 471854:DFER_RS04990
uniprot id: C6W425
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS07535
gene id: 471854:DFER_RS07535
uniprot id: C6VRS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

471854:DFER RS06300
gene id: 471854:DFER_RS06300
uniprot id: C6W644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

471854:DFER RS13485
gene id: 471854:DFER_RS13485
uniprot id: C6W3G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

471854:DFER RS00830
gene id: 471854:DFER_RS00830
uniprot id: C6VVY6
names: Subcellular Location Annotation
messages: Cell inner membrane

471854:DFER RS09385
gene id: 471854:DFER_RS09385
uniprot id: C6VW06
names: Similarity
messages: Belongs to the SusD family.

471854:DFER RS19535
gene id: 471854:DFER_RS19535
uniprot id: C6VXU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

471854:DFER RS05500
gene id: 471854:DFER_RS05500
uniprot id: C6W504
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.