470934:EGO56 RS17340
gene id: 470934:EGO56_RS17340
uniprot id: A0A109YCB3
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

470934:EGO56 RS18260
gene id: 470934:EGO56_RS18260
uniprot id: A0A7Z2B2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

470934:EGO56 RS01600
gene id: 470934:EGO56_RS01600
uniprot id: A0A7Z1Y0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

470934:EGO56 RS02245
gene id: 470934:EGO56_RS02245
uniprot id: A0A0X8Q9J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

470934:EGO56 RS00780
gene id: 470934:EGO56_RS00780
uniprot id: A0A7Z1Y0Z5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

470934:EGO56 RS06090
gene id: 470934:EGO56_RS06090
uniprot id: A0A7Z1Y250
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

470934:EGO56 RS20895
gene id: 470934:EGO56_RS20895
uniprot id: A0A7U4T9D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS08615
gene id: 470934:EGO56_RS08615
uniprot id: A0A7Z1Y2T3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

470934:EGO56 RS19945
gene id: 470934:EGO56_RS19945
uniprot id: A0A7Z1Y710
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS06585
gene id: 470934:EGO56_RS06585
uniprot id: A0A7Z2B1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

470934:EGO56 RS04805
gene id: 470934:EGO56_RS04805
uniprot id: A0A7Z1Y1G6
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

470934:EGO56 RS09010
gene id: 470934:EGO56_RS09010
uniprot id: A0A7Z1Y2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

470934:EGO56 RS00270
gene id: 470934:EGO56_RS00270
uniprot id: A0A2R4J3F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

470934:EGO56 RS12875
gene id: 470934:EGO56_RS12875
uniprot id: A0A7Z2B1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

470934:EGO56 RS05810
gene id: 470934:EGO56_RS05810
uniprot id: A0A7Z1Y1P7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M74 family.
messages: Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.
messages: Dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
messages: Periplasm

470934:EGO56 RS12635
gene id: 470934:EGO56_RS12635
uniprot id: A0A7Z2B1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

470934:EGO56 RS13640
gene id: 470934:EGO56_RS13640
uniprot id: A0A2R4J665
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

470934:EGO56 RS05885
gene id: 470934:EGO56_RS05885
uniprot id: A0A7U4Q980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS00545
gene id: 470934:EGO56_RS00545
uniprot id: A0A7Z1Y0V5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

470934:EGO56 RS02405
gene id: 470934:EGO56_RS02405
uniprot id: A0A7U4QAG8
names: Similarity
messages: Belongs to the Smg family.

470934:EGO56 RS04855
gene id: 470934:EGO56_RS04855
uniprot id: A0A7U4Q9I7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

470934:EGO56 RS01455
gene id: 470934:EGO56_RS01455
uniprot id: A0A7Z1Y0C6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

470934:EGO56 RS14575
gene id: 470934:EGO56_RS14575
uniprot id: A0A7Z2B0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

470934:EGO56 RS05200
gene id: 470934:EGO56_RS05200
uniprot id: A0A7Z1Y1G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

470934:EGO56 RS02190
gene id: 470934:EGO56_RS02190
uniprot id: A0A7Z2AZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

470934:EGO56 RS03165
gene id: 470934:EGO56_RS03165
uniprot id: A0A7Z2B179
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS06570
gene id: 470934:EGO56_RS06570
uniprot id: A0A7Z1Y292
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS12575
gene id: 470934:EGO56_RS12575
uniprot id: A0A7Z1Y443
names: Caution
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS19595
gene id: 470934:EGO56_RS19595
uniprot id: A0A7Z2B355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03525
gene id: 470934:EGO56_RS03525
uniprot id: A0A7Z1Y0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS01560
gene id: 470934:EGO56_RS01560
uniprot id: A0A7Z2B2D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

470934:EGO56 RS16130
gene id: 470934:EGO56_RS16130
uniprot id: A0A7Z1Y5G7
names: Similarity
messages: Belongs to the threonine synthase family.

470934:EGO56 RS08695
gene id: 470934:EGO56_RS08695
uniprot id: A0A7U4Q895
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

470934:EGO56 RS05925
gene id: 470934:EGO56_RS05925
uniprot id: A0A7Z1Y1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

470934:EGO56 RS09420
gene id: 470934:EGO56_RS09420
uniprot id: A0A7Z1Y7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

470934:EGO56 RS14250
gene id: 470934:EGO56_RS14250
uniprot id: A0A7Z2B3A4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS14730
gene id: 470934:EGO56_RS14730
uniprot id: A0A7Z2B265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

470934:EGO56 RS07165
gene id: 470934:EGO56_RS07165
uniprot id: A0A7Z1Y281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS07745
gene id: 470934:EGO56_RS07745
uniprot id: A0A7Z1Y2K9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

470934:EGO56 RS15005
gene id: 470934:EGO56_RS15005
uniprot id: A0A109YAJ1
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS08835
gene id: 470934:EGO56_RS08835
uniprot id: A0A7Z2B256
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

470934:EGO56 RS15990
gene id: 470934:EGO56_RS15990
uniprot id: A0A7Z1Y5N8
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

470934:EGO56 RS17205
gene id: 470934:EGO56_RS17205
uniprot id: A0A7Z1Y5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

470934:EGO56 RS10785
gene id: 470934:EGO56_RS10785
uniprot id: A0A7Z1Y3I6
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS12520
gene id: 470934:EGO56_RS12520
uniprot id: A0A7Z1Y442
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

470934:EGO56 RS05545
gene id: 470934:EGO56_RS05545
uniprot id: A0A7U4Q9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

470934:EGO56 RS11790
gene id: 470934:EGO56_RS11790
uniprot id: A0A7Z1Y439
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

470934:EGO56 RS02265
gene id: 470934:EGO56_RS02265
uniprot id: A0A109YC61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

470934:EGO56 RS06055
gene id: 470934:EGO56_RS06055
uniprot id: A0A501SEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS06110
gene id: 470934:EGO56_RS06110
uniprot id: A0A5K4ZPF6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

470934:EGO56 RS04170
gene id: 470934:EGO56_RS04170
uniprot id: A0A7Z1Y1D3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS05410
gene id: 470934:EGO56_RS05410
uniprot id: A0A7Z1Y1L5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS13595
gene id: 470934:EGO56_RS13595
uniprot id: A0A7Z1Y4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

470934:EGO56 RS09310
gene id: 470934:EGO56_RS09310
uniprot id: A0A7Z2B285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS04880
gene id: 470934:EGO56_RS04880
uniprot id: A0A7Z1Y1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

470934:EGO56 RS07500
gene id: 470934:EGO56_RS07500
uniprot id: A0A7Z1Y2H0
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

470934:EGO56 RS06010
gene id: 470934:EGO56_RS06010
uniprot id: A0A7Z1Y217
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

470934:EGO56 RS11720
gene id: 470934:EGO56_RS11720
uniprot id: A0A120LP58
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

470934:EGO56 RS01555
gene id: 470934:EGO56_RS01555
uniprot id: A0A501S2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

470934:EGO56 RS10060
gene id: 470934:EGO56_RS10060
uniprot id: A0A7Z2AZU3
names: Similarity
messages: Belongs to the barstar family.

470934:EGO56 RS17990
gene id: 470934:EGO56_RS17990
uniprot id: A0A7Z1Y615
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

470934:EGO56 RS07895
gene id: 470934:EGO56_RS07895
uniprot id: A0A7Z1Y2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

470934:EGO56 RS18035
gene id: 470934:EGO56_RS18035
uniprot id: A0A0X8Q449
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

470934:EGO56 RS09185
gene id: 470934:EGO56_RS09185
uniprot id: A0A7Z1Y2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

470934:EGO56 RS16960
gene id: 470934:EGO56_RS16960
uniprot id: A0A7Z1Y7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

470934:EGO56 RS02580
gene id: 470934:EGO56_RS02580
uniprot id: A0A2R4J267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

470934:EGO56 RS02035
gene id: 470934:EGO56_RS02035
uniprot id: A0A7Z2AYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

470934:EGO56 RS10715
gene id: 470934:EGO56_RS10715
uniprot id: A0A7Z1Y3R4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

470934:EGO56 RS13730
gene id: 470934:EGO56_RS13730
uniprot id: A0A7Z2B375
names: Similarity
messages: Belongs to the citrate synthase family.

470934:EGO56 RS11375
gene id: 470934:EGO56_RS11375
uniprot id: A0A7U4Q7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

470934:EGO56 RS13010
gene id: 470934:EGO56_RS13010
uniprot id: A0A2R4J6I7
names: Subunit
messages: Monomer.

470934:EGO56 RS03510
gene id: 470934:EGO56_RS03510
uniprot id: A0A7U4QA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Cytoplasm
messages: Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
messages: Monomer.

470934:EGO56 RS09200
gene id: 470934:EGO56_RS09200
uniprot id: A0A7Z1Y337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS04005
gene id: 470934:EGO56_RS04005
uniprot id: A0A7Z1Y149
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS02225
gene id: 470934:EGO56_RS02225
uniprot id: A0A0X8Q9U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS17260
gene id: 470934:EGO56_RS17260
uniprot id: A0A7U4Q5H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

470934:EGO56 RS06115
gene id: 470934:EGO56_RS06115
uniprot id: A0A7Z2AZ52
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

470934:EGO56 RS16170
gene id: 470934:EGO56_RS16170
uniprot id: A0A7Z2B3L1
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS02155
gene id: 470934:EGO56_RS02155
uniprot id: A0A7Z1Y0P9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

470934:EGO56 RS00885
gene id: 470934:EGO56_RS00885
uniprot id: A0A7Z1Y024
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

470934:EGO56 RS02340
gene id: 470934:EGO56_RS02340
uniprot id: A0A0U3UMG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

470934:EGO56 RS04900
gene id: 470934:EGO56_RS04900
uniprot id: A0A7Z1Y1N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

470934:EGO56 RS02570
gene id: 470934:EGO56_RS02570
uniprot id: A0A7Z1Y117
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Probable metalloprotease.

470934:EGO56 RS13020
gene id: 470934:EGO56_RS13020
uniprot id: A0A7Z2B331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

470934:EGO56 RS02230
gene id: 470934:EGO56_RS02230
uniprot id: A0A501S4A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

470934:EGO56 RS02880
gene id: 470934:EGO56_RS02880
uniprot id: A0A7Z1Y6K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

470934:EGO56 RS00245
gene id: 470934:EGO56_RS00245
uniprot id: A0A7Z1Y009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS15345
gene id: 470934:EGO56_RS15345
uniprot id: A0A2R4J5B5
names: Similarity
messages: Belongs to the UPF0253 family.

470934:EGO56 RS11605
gene id: 470934:EGO56_RS11605
uniprot id: A0A7Z1Y3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

470934:EGO56 RS15605
gene id: 470934:EGO56_RS15605
uniprot id: A0A7Z2B4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS01090
gene id: 470934:EGO56_RS01090
uniprot id: A0A7U4Q4I6
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

470934:EGO56 RS00020
gene id: 470934:EGO56_RS00020
uniprot id: A0A7Z2B237
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

470934:EGO56 RS12980
gene id: 470934:EGO56_RS12980
uniprot id: A0A7U4TB97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

470934:EGO56 RS11580
gene id: 470934:EGO56_RS11580
uniprot id: A0A7Z2B1L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

470934:EGO56 RS13695
gene id: 470934:EGO56_RS13695
uniprot id: A0A120LP23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

470934:EGO56 RS08610
gene id: 470934:EGO56_RS08610
uniprot id: A0A7Z1Y3Q6
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

470934:EGO56 RS12840
gene id: 470934:EGO56_RS12840
uniprot id: A0A0X8Q5R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

470934:EGO56 RS09510
gene id: 470934:EGO56_RS09510
uniprot id: A0A7U4QB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

470934:EGO56 RS10280
gene id: 470934:EGO56_RS10280
uniprot id: A0A7Z1Y3L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS06285
gene id: 470934:EGO56_RS06285
uniprot id: A0A7Z1Y1X2
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

470934:EGO56 RS03160
gene id: 470934:EGO56_RS03160
uniprot id: A0A7Z2B2M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

470934:EGO56 RS17060
gene id: 470934:EGO56_RS17060
uniprot id: A0A7Z1Y5M6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS19855
gene id: 470934:EGO56_RS19855
uniprot id: A0A7Z1Y701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS13110
gene id: 470934:EGO56_RS13110
uniprot id: A0A7Z1Y4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS02500
gene id: 470934:EGO56_RS02500
uniprot id: A0A7U4QAG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

470934:EGO56 RS05965
gene id: 470934:EGO56_RS05965
uniprot id: A0A7Z2B0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03225
gene id: 470934:EGO56_RS03225
uniprot id: A0A7Z2B5C6
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

470934:EGO56 RS13840
gene id: 470934:EGO56_RS13840
uniprot id: A0A7Z1Y4J6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS12780
gene id: 470934:EGO56_RS12780
uniprot id: A0A120LP41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

470934:EGO56 RS17880
gene id: 470934:EGO56_RS17880
uniprot id: A0A7Z2B166
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

470934:EGO56 RS18220
gene id: 470934:EGO56_RS18220
uniprot id: A0A7Z1Y620
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

470934:EGO56 RS06340
gene id: 470934:EGO56_RS06340
uniprot id: A0A501SE15
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

470934:EGO56 RS04925
gene id: 470934:EGO56_RS04925
uniprot id: A0A7Z2B1P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

470934:EGO56 RS09990
gene id: 470934:EGO56_RS09990
uniprot id: A0A7U4Q7V4
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

470934:EGO56 RS20605
gene id: 470934:EGO56_RS20605
uniprot id: A0A7Z1Y781
names: Similarity
messages: Belongs to the sterol desaturase family.

470934:EGO56 RS01345
gene id: 470934:EGO56_RS01345
uniprot id: A0A2R4J2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03440
gene id: 470934:EGO56_RS03440
uniprot id: A0A1W9ES74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

470934:EGO56 RS01610
gene id: 470934:EGO56_RS01610
uniprot id: A0A7U4QAR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

470934:EGO56 RS07880
gene id: 470934:EGO56_RS07880
uniprot id: A0A7Z1Y2G3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

470934:EGO56 RS06135
gene id: 470934:EGO56_RS06135
uniprot id: A0A7Z1Y1Z9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

470934:EGO56 RS14385
gene id: 470934:EGO56_RS14385
uniprot id: A0A7U4TAX4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

470934:EGO56 RS02250
gene id: 470934:EGO56_RS02250
uniprot id: A0A2R4J2D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

470934:EGO56 RS17005
gene id: 470934:EGO56_RS17005
uniprot id: A0A7Z2B3M6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

470934:EGO56 RS05060
gene id: 470934:EGO56_RS05060
uniprot id: A0A109YBT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

470934:EGO56 RS10200
gene id: 470934:EGO56_RS10200
uniprot id: A0A7U4TBB3
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

470934:EGO56 RS22185
gene id: 470934:EGO56_RS22185
uniprot id: A0A7Z2B4U0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

470934:EGO56 RS04220
gene id: 470934:EGO56_RS04220
uniprot id: A0A7Z2B1K1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

470934:EGO56 RS07875
gene id: 470934:EGO56_RS07875
uniprot id: A0A7Z2B0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS13990
gene id: 470934:EGO56_RS13990
uniprot id: A0A7Z1Y6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

470934:EGO56 RS17850
gene id: 470934:EGO56_RS17850
uniprot id: A0A7Z1Y6C1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

470934:EGO56 RS04100
gene id: 470934:EGO56_RS04100
uniprot id: A0A1W9ERT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS10615
gene id: 470934:EGO56_RS10615
uniprot id: A0A7Z1Y6G2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

470934:EGO56 RS04995
gene id: 470934:EGO56_RS04995
uniprot id: A0A7Z2B2Z3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

470934:EGO56 RS10215
gene id: 470934:EGO56_RS10215
uniprot id: A0A7Z2B2E0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

470934:EGO56 RS17885
gene id: 470934:EGO56_RS17885
uniprot id: A0A7Z2B2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

470934:EGO56 RS06370
gene id: 470934:EGO56_RS06370
uniprot id: A0A7Z1Y2X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

470934:EGO56 RS04465
gene id: 470934:EGO56_RS04465
uniprot id: A0A7Z1Y1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

470934:EGO56 RS08210
gene id: 470934:EGO56_RS08210
uniprot id: A0A7Z1Y2P2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS11355
gene id: 470934:EGO56_RS11355
uniprot id: A0A7U4Q7D3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

470934:EGO56 RS06770
gene id: 470934:EGO56_RS06770
uniprot id: A0A501SGG0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

470934:EGO56 RS02180
gene id: 470934:EGO56_RS02180
uniprot id: A0A120LPQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

470934:EGO56 RS06325
gene id: 470934:EGO56_RS06325
uniprot id: A0A501SG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

470934:EGO56 RS13850
gene id: 470934:EGO56_RS13850
uniprot id: A0A7U4Q6M0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

470934:EGO56 RS08720
gene id: 470934:EGO56_RS08720
uniprot id: A0A7Z1Y2S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

470934:EGO56 RS12925
gene id: 470934:EGO56_RS12925
uniprot id: A0A7Z1Y4J2
names: Similarity
messages: Belongs to the UPF0145 family.

470934:EGO56 RS05275
gene id: 470934:EGO56_RS05275
uniprot id: A0A7U4Q9K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

470934:EGO56 RS10625
gene id: 470934:EGO56_RS10625
uniprot id: A0A7Z1Y3R0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

470934:EGO56 RS15245
gene id: 470934:EGO56_RS15245
uniprot id: A0A7Z1Y5F4
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

470934:EGO56 RS18155
gene id: 470934:EGO56_RS18155
uniprot id: A0A7Z2B178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

470934:EGO56 RS01405
gene id: 470934:EGO56_RS01405
uniprot id: A0A501S7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

470934:EGO56 RS14800
gene id: 470934:EGO56_RS14800
uniprot id: A0A7Z2B0M8
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

470934:EGO56 RS15475
gene id: 470934:EGO56_RS15475
uniprot id: A0A7Z1Y624
names: Similarity
messages: Belongs to the UPF0325 family.

470934:EGO56 RS17300
gene id: 470934:EGO56_RS17300
uniprot id: A0A120LNU8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

470934:EGO56 RS15405
gene id: 470934:EGO56_RS15405
uniprot id: A0A7Z1Y569
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

470934:EGO56 RS16300
gene id: 470934:EGO56_RS16300
uniprot id: A0A7Z1Y5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

470934:EGO56 RS17935
gene id: 470934:EGO56_RS17935
uniprot id: A0A7Z1Y680
names: Similarity
messages: Belongs to the aspartokinase family.

470934:EGO56 RS12675
gene id: 470934:EGO56_RS12675
uniprot id: A0A7Z1Y4A2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS15375
gene id: 470934:EGO56_RS15375
uniprot id: A0A7Z2B3H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

470934:EGO56 RS14370
gene id: 470934:EGO56_RS14370
uniprot id: A0A7Z1Y4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

470934:EGO56 RS01695
gene id: 470934:EGO56_RS01695
uniprot id: A0A7Z1Y0C8
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

470934:EGO56 RS18710
gene id: 470934:EGO56_RS18710
uniprot id: A0A7Z1Y667
names: Similarity
messages: Belongs to the OsmC/Ohr family.

470934:EGO56 RS17920
gene id: 470934:EGO56_RS17920
uniprot id: A0A7Z1Y698
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03000
gene id: 470934:EGO56_RS03000
uniprot id: A0A7Z2B169
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

470934:EGO56 RS15425
gene id: 470934:EGO56_RS15425
uniprot id: A0A7Z1Y5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

470934:EGO56 RS10965
gene id: 470934:EGO56_RS10965
uniprot id: A0A7Z1Y3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS12945
gene id: 470934:EGO56_RS12945
uniprot id: A0A501SET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS14060
gene id: 470934:EGO56_RS14060
uniprot id: A0A0X8Q555
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS02110
gene id: 470934:EGO56_RS02110
uniprot id: A0A7Z2AYH7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS09165
gene id: 470934:EGO56_RS09165
uniprot id: A0A7Z2B162
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

470934:EGO56 RS00380
gene id: 470934:EGO56_RS00380
uniprot id: A0A7U5TYS7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS04000
gene id: 470934:EGO56_RS04000
uniprot id: A0A7Z2B2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

470934:EGO56 RS17185
gene id: 470934:EGO56_RS17185
uniprot id: A0A2R4J4F9
names: Similarity
messages: Belongs to the BolA/IbaG family.

470934:EGO56 RS12815
gene id: 470934:EGO56_RS12815
uniprot id: A0A7Z1Y467
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS20210
gene id: 470934:EGO56_RS20210
uniprot id: A0A7Z1Y7A7
names: Similarity
messages: Belongs to the pirin family.

470934:EGO56 RS15895
gene id: 470934:EGO56_RS15895
uniprot id: A0A7Z1Y5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

470934:EGO56 RS00300
gene id: 470934:EGO56_RS00300
uniprot id: A0A0U3V4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

470934:EGO56 RS04810
gene id: 470934:EGO56_RS04810
uniprot id: A0A7U4TCN4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

470934:EGO56 RS14140
gene id: 470934:EGO56_RS14140
uniprot id: A0A7Z1Y4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

470934:EGO56 RS04105
gene id: 470934:EGO56_RS04105
uniprot id: A0A501SAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

470934:EGO56 RS02085
gene id: 470934:EGO56_RS02085
uniprot id: A0A7U4QAL1
names: Similarity
messages: Belongs to the UPF0270 family.

470934:EGO56 RS12890
gene id: 470934:EGO56_RS12890
uniprot id: A0A2R4J6G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

470934:EGO56 RS18875
gene id: 470934:EGO56_RS18875
uniprot id: A0A7Z1Y685
names: Function
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.
messages: May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.

470934:EGO56 RS17285
gene id: 470934:EGO56_RS17285
uniprot id: A0A7Z1Y5T7
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

470934:EGO56 RS12625
gene id: 470934:EGO56_RS12625
uniprot id: A0A7Z2B306
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

470934:EGO56 RS16020
gene id: 470934:EGO56_RS16020
uniprot id: A0A7Z2B0V6
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

470934:EGO56 RS13475
gene id: 470934:EGO56_RS13475
uniprot id: A0A7Z2B360
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS10600
gene id: 470934:EGO56_RS10600
uniprot id: A0A7Z1Y3K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

470934:EGO56 RS00690
gene id: 470934:EGO56_RS00690
uniprot id: A0A7Z2AY83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

470934:EGO56 RS04375
gene id: 470934:EGO56_RS04375
uniprot id: A0A7U4TC74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

470934:EGO56 RS17020
gene id: 470934:EGO56_RS17020
uniprot id: A0A7Z2B110
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

470934:EGO56 RS18520
gene id: 470934:EGO56_RS18520
uniprot id: A0A109YA48
names: Similarity
messages: Belongs to the thioredoxin family.

470934:EGO56 RS02010
gene id: 470934:EGO56_RS02010
uniprot id: A0A7Z1Y0U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS13900
gene id: 470934:EGO56_RS13900
uniprot id: A0A7Z1Y4X1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

470934:EGO56 RS10695
gene id: 470934:EGO56_RS10695
uniprot id: A0A7Z1Y3G9
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

470934:EGO56 RS14375
gene id: 470934:EGO56_RS14375
uniprot id: A0A7Z1Y4W0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

470934:EGO56 RS14715
gene id: 470934:EGO56_RS14715
uniprot id: A0A7Z2B373
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

470934:EGO56 RS06145
gene id: 470934:EGO56_RS06145
uniprot id: A0A7Z1Y1W5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

470934:EGO56 RS08705
gene id: 470934:EGO56_RS08705
uniprot id: A0A7Z1Y3R6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

470934:EGO56 RS15250
gene id: 470934:EGO56_RS15250
uniprot id: A0A7Z1Y5C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

470934:EGO56 RS03275
gene id: 470934:EGO56_RS03275
uniprot id: A0A7Z1Y128
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

470934:EGO56 RS17380
gene id: 470934:EGO56_RS17380
uniprot id: A0A7Z1Y658
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

470934:EGO56 RS15840
gene id: 470934:EGO56_RS15840
uniprot id: A0A7U4Q5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

470934:EGO56 RS15430
gene id: 470934:EGO56_RS15430
uniprot id: A0A7Z1Y5E3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

470934:EGO56 RS12800
gene id: 470934:EGO56_RS12800
uniprot id: A0A7Z2B1U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS18320
gene id: 470934:EGO56_RS18320
uniprot id: A0A7Z2B3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

470934:EGO56 RS10595
gene id: 470934:EGO56_RS10595
uniprot id: A0A7Z1Y3F9
names: Similarity
messages: Belongs to the pyruvate kinase family.

470934:EGO56 RS13125
gene id: 470934:EGO56_RS13125
uniprot id: A0A7Z1Y4D7
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

470934:EGO56 RS20510
gene id: 470934:EGO56_RS20510
uniprot id: A0A7Z1Y762
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS05345
gene id: 470934:EGO56_RS05345
uniprot id: A0A7Z1Y1R6
names: Subunit
messages: Homodimer.

470934:EGO56 RS02305
gene id: 470934:EGO56_RS02305
uniprot id: A0A0X8Q9T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

470934:EGO56 RS02345
gene id: 470934:EGO56_RS02345
uniprot id: A0A109YC81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

470934:EGO56 RS15775
gene id: 470934:EGO56_RS15775
uniprot id: A0A7Z2B4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

470934:EGO56 RS07585
gene id: 470934:EGO56_RS07585
uniprot id: A0A7Z1Y2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

470934:EGO56 RS14505
gene id: 470934:EGO56_RS14505
uniprot id: A0A109YAN8
names: Similarity
messages: Belongs to the P(II) protein family.

470934:EGO56 RS04255
gene id: 470934:EGO56_RS04255
uniprot id: A0A7Z1Y178
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

470934:EGO56 RS15085
gene id: 470934:EGO56_RS15085
uniprot id: A0A7Z1Y4Y8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS06590
gene id: 470934:EGO56_RS06590
uniprot id: A0A7U4Q8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

470934:EGO56 RS07730
gene id: 470934:EGO56_RS07730
uniprot id: A0A2R4J9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

470934:EGO56 RS17325
gene id: 470934:EGO56_RS17325
uniprot id: A0A7U4Q5C5
names: Similarity
messages: Belongs to the peptidase S1C family.

470934:EGO56 RS01020
gene id: 470934:EGO56_RS01020
uniprot id: A0A7Z1Y028
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS04505
gene id: 470934:EGO56_RS04505
uniprot id: A0A7Z1Y1H5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

470934:EGO56 RS04825
gene id: 470934:EGO56_RS04825
uniprot id: A0A2R4JAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

470934:EGO56 RS08945
gene id: 470934:EGO56_RS08945
uniprot id: A0A7Z1Y2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

470934:EGO56 RS15645
gene id: 470934:EGO56_RS15645
uniprot id: A0A7Z1Y599
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

470934:EGO56 RS16150
gene id: 470934:EGO56_RS16150
uniprot id: A0A7Z1Y5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS16955
gene id: 470934:EGO56_RS16955
uniprot id: A0A7Z1Y5P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

470934:EGO56 RS00290
gene id: 470934:EGO56_RS00290
uniprot id: A0A0X8Q3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

470934:EGO56 RS13700
gene id: 470934:EGO56_RS13700
uniprot id: A0A7Z1Y4I0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

470934:EGO56 RS09440
gene id: 470934:EGO56_RS09440
uniprot id: A0A7Z1Y321
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

470934:EGO56 RS08730
gene id: 470934:EGO56_RS08730
uniprot id: A0A7Z1Y2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS17365
gene id: 470934:EGO56_RS17365
uniprot id: A0A2R4J4A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

470934:EGO56 RS16135
gene id: 470934:EGO56_RS16135
uniprot id: A0A7Z1Y5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

470934:EGO56 RS13100
gene id: 470934:EGO56_RS13100
uniprot id: A0A109YAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

470934:EGO56 RS02700
gene id: 470934:EGO56_RS02700
uniprot id: A0A7Z1Y1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

470934:EGO56 RS18675
gene id: 470934:EGO56_RS18675
uniprot id: A0A7Z2B1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS06100
gene id: 470934:EGO56_RS06100
uniprot id: A0A7Z2B352
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

470934:EGO56 RS15490
gene id: 470934:EGO56_RS15490
uniprot id: A0A7Z1Y560
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

470934:EGO56 RS17215
gene id: 470934:EGO56_RS17215
uniprot id: A0A7Z1Y5Q6
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS13740
gene id: 470934:EGO56_RS13740
uniprot id: A0A7Z2B201
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

470934:EGO56 RS18500
gene id: 470934:EGO56_RS18500
uniprot id: A0A7Z2B3W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS01005
gene id: 470934:EGO56_RS01005
uniprot id: A0A7Z1Y026
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

470934:EGO56 RS06095
gene id: 470934:EGO56_RS06095
uniprot id: A0A7Z1Y269
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

470934:EGO56 RS15395
gene id: 470934:EGO56_RS15395
uniprot id: A0A7U4Q621
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

470934:EGO56 RS13715
gene id: 470934:EGO56_RS13715
uniprot id: A0A7Z1Y4U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

470934:EGO56 RS06255
gene id: 470934:EGO56_RS06255
uniprot id: A0A7Z1Y288
names: Similarity
messages: Belongs to the peptidase C40 family.

470934:EGO56 RS05815
gene id: 470934:EGO56_RS05815
uniprot id: A0A7Z1Y2R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS17160
gene id: 470934:EGO56_RS17160
uniprot id: A0A109YAA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

470934:EGO56 RS02205
gene id: 470934:EGO56_RS02205
uniprot id: A0A7Z1Y0Q6
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

470934:EGO56 RS02770
gene id: 470934:EGO56_RS02770
uniprot id: A0A7U4TC21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

470934:EGO56 RS01605
gene id: 470934:EGO56_RS01605
uniprot id: A0A2R4J2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

470934:EGO56 RS03470
gene id: 470934:EGO56_RS03470
uniprot id: A0A7Z1Y175
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

470934:EGO56 RS13705
gene id: 470934:EGO56_RS13705
uniprot id: A0A7Z1Y4V4
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

470934:EGO56 RS06240
gene id: 470934:EGO56_RS06240
uniprot id: A0A7U4TBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS03625
gene id: 470934:EGO56_RS03625
uniprot id: A0A7Z1Y181
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

470934:EGO56 RS10155
gene id: 470934:EGO56_RS10155
uniprot id: A0A7Z1Y484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

470934:EGO56 RS03735
gene id: 470934:EGO56_RS03735
uniprot id: A0A7Z2AYS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

470934:EGO56 RS08815
gene id: 470934:EGO56_RS08815
uniprot id: A0A7U4Q8C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

470934:EGO56 RS07550
gene id: 470934:EGO56_RS07550
uniprot id: A0A7Z2AZE1
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

470934:EGO56 RS02335
gene id: 470934:EGO56_RS02335
uniprot id: A0A109YC68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

470934:EGO56 RS15620
gene id: 470934:EGO56_RS15620
uniprot id: A0A7Z2B0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

470934:EGO56 RS04180
gene id: 470934:EGO56_RS04180
uniprot id: A0A7Z1Y164
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

470934:EGO56 RS13145
gene id: 470934:EGO56_RS13145
uniprot id: A0A7Z1Y4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

470934:EGO56 RS04110
gene id: 470934:EGO56_RS04110
uniprot id: A0A7Z1Y1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

470934:EGO56 RS03835
gene id: 470934:EGO56_RS03835
uniprot id: A0A7Z1Y243
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

470934:EGO56 RS10705
gene id: 470934:EGO56_RS10705
uniprot id: A0A0X8Q7G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

470934:EGO56 RS07900
gene id: 470934:EGO56_RS07900
uniprot id: A0A7Z1Y2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

470934:EGO56 RS16990
gene id: 470934:EGO56_RS16990
uniprot id: A0A5K4Z8C6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

470934:EGO56 RS18685
gene id: 470934:EGO56_RS18685
uniprot id: A0A7Z1Y679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

470934:EGO56 RS04425
gene id: 470934:EGO56_RS04425
uniprot id: A0A7Z1Y2A0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

470934:EGO56 RS17220
gene id: 470934:EGO56_RS17220
uniprot id: A0A7Z1Y5W3
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

470934:EGO56 RS08970
gene id: 470934:EGO56_RS08970
uniprot id: A0A7Z1Y336
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

470934:EGO56 RS02790
gene id: 470934:EGO56_RS02790
uniprot id: A0A7Z1Y0P5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

470934:EGO56 RS11760
gene id: 470934:EGO56_RS11760
uniprot id: A0A7Z1Y3Y7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

470934:EGO56 RS18250
gene id: 470934:EGO56_RS18250
uniprot id: A0A7Z2B3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

470934:EGO56 RS12860
gene id: 470934:EGO56_RS12860
uniprot id: A0A7Z2B2W3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

470934:EGO56 RS05795
gene id: 470934:EGO56_RS05795
uniprot id: A0A7Z2B1T9
names: Similarity
messages: Belongs to the UPF0115 family.

470934:EGO56 RS21480
gene id: 470934:EGO56_RS21480
uniprot id: A0A7Z1Y7I2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

470934:EGO56 RS17235
gene id: 470934:EGO56_RS17235
uniprot id: A0A7Z1Y611
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

470934:EGO56 RS06030
gene id: 470934:EGO56_RS06030
uniprot id: A0A2R4JAB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS15590
gene id: 470934:EGO56_RS15590
uniprot id: A0A7Z1Y5J1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

470934:EGO56 RS04875
gene id: 470934:EGO56_RS04875
uniprot id: A0A7Z1Y1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

470934:EGO56 RS09995
gene id: 470934:EGO56_RS09995
uniprot id: A0A1W9EZN9
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

470934:EGO56 RS05285
gene id: 470934:EGO56_RS05285
uniprot id: A0A7U4Q9D6
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS14720
gene id: 470934:EGO56_RS14720
uniprot id: A0A7U4Q698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

470934:EGO56 RS15155
gene id: 470934:EGO56_RS15155
uniprot id: A0A7Z1Y555
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

470934:EGO56 RS18510
gene id: 470934:EGO56_RS18510
uniprot id: A0A7Z2B3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS06750
gene id: 470934:EGO56_RS06750
uniprot id: A0A7Z2AZ92
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

470934:EGO56 RS04195
gene id: 470934:EGO56_RS04195
uniprot id: A0A7Z1Y1F5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

470934:EGO56 RS08215
gene id: 470934:EGO56_RS08215
uniprot id: A0A7Z1Y2Q5
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

470934:EGO56 RS02945
gene id: 470934:EGO56_RS02945
uniprot id: A0A2R4JC48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

470934:EGO56 RS08170
gene id: 470934:EGO56_RS08170
uniprot id: A0A7Z2B3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS11480
gene id: 470934:EGO56_RS11480
uniprot id: A0A7Z2B444
names: Function
names: Similarity
messages: Belongs to the FumD family.
messages: In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate.

470934:EGO56 RS18290
gene id: 470934:EGO56_RS18290
uniprot id: A0A7Z1Y6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

470934:EGO56 RS03790
gene id: 470934:EGO56_RS03790
uniprot id: A0A7Z1Y1G9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

470934:EGO56 RS11800
gene id: 470934:EGO56_RS11800
uniprot id: A0A120LP56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

470934:EGO56 RS03145
gene id: 470934:EGO56_RS03145
uniprot id: A0A109YC35
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

470934:EGO56 RS19825
gene id: 470934:EGO56_RS19825
uniprot id: A0A7Z2B1Q7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

470934:EGO56 RS06415
gene id: 470934:EGO56_RS06415
uniprot id: A0A7Z2B371
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

470934:EGO56 RS20530
gene id: 470934:EGO56_RS20530
uniprot id: A0A2R4JDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS19585
gene id: 470934:EGO56_RS19585
uniprot id: A0A7Z2B4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS02315
gene id: 470934:EGO56_RS02315
uniprot id: A0A0X8Q9G5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS10150
gene id: 470934:EGO56_RS10150
uniprot id: A0A7Z1Y396
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS06740
gene id: 470934:EGO56_RS06740
uniprot id: A0A7Z2B1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

470934:EGO56 RS14995
gene id: 470934:EGO56_RS14995
uniprot id: A0A7Z1Y534
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

470934:EGO56 RS15370
gene id: 470934:EGO56_RS15370
uniprot id: A0A7Z2B3B5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

470934:EGO56 RS18525
gene id: 470934:EGO56_RS18525
uniprot id: A0A7Z1Y662
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

470934:EGO56 RS15400
gene id: 470934:EGO56_RS15400
uniprot id: A0A0X8Q4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

470934:EGO56 RS06600
gene id: 470934:EGO56_RS06600
uniprot id: A0A7Z2B0R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS00935
gene id: 470934:EGO56_RS00935
uniprot id: A0A7Z1Y109
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

470934:EGO56 RS03925
gene id: 470934:EGO56_RS03925
uniprot id: A0A7Z1Y141
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS14100
gene id: 470934:EGO56_RS14100
uniprot id: A0A7U4QB04
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS05450
gene id: 470934:EGO56_RS05450
uniprot id: A0A7Z1Y1Y2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

470934:EGO56 RS21180
gene id: 470934:EGO56_RS21180
uniprot id: A0A7Z1Y7E3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

470934:EGO56 RS00825
gene id: 470934:EGO56_RS00825
uniprot id: A0A7Z1Y086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

470934:EGO56 RS06070
gene id: 470934:EGO56_RS06070
uniprot id: A0A7Z1Y1V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS16080
gene id: 470934:EGO56_RS16080
uniprot id: A0A0X8Q4C7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

470934:EGO56 RS04500
gene id: 470934:EGO56_RS04500
uniprot id: A0A7Z1Y2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

470934:EGO56 RS18740
gene id: 470934:EGO56_RS18740
uniprot id: A0A7Z1Y6H6
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

470934:EGO56 RS03665
gene id: 470934:EGO56_RS03665
uniprot id: A0A7Z1Y111
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

470934:EGO56 RS04840
gene id: 470934:EGO56_RS04840
uniprot id: A0A7Z2B1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

470934:EGO56 RS11095
gene id: 470934:EGO56_RS11095
uniprot id: A0A7Z1Y4K9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

470934:EGO56 RS14625
gene id: 470934:EGO56_RS14625
uniprot id: A0A7U4Q6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS01850
gene id: 470934:EGO56_RS01850
uniprot id: A0A7Z1Y0K4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

470934:EGO56 RS15385
gene id: 470934:EGO56_RS15385
uniprot id: A0A7Z2B2A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

470934:EGO56 RS04050
gene id: 470934:EGO56_RS04050
uniprot id: A0A7Z2B1D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

470934:EGO56 RS12390
gene id: 470934:EGO56_RS12390
uniprot id: A0A7Z2B085
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

470934:EGO56 RS14320
gene id: 470934:EGO56_RS14320
uniprot id: A0A7Z2B4K4
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS11060
gene id: 470934:EGO56_RS11060
uniprot id: A0A7Z1Y3V8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

470934:EGO56 RS16270
gene id: 470934:EGO56_RS16270
uniprot id: A0A2R4J4Q8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

470934:EGO56 RS16260
gene id: 470934:EGO56_RS16260
uniprot id: A0A7Z2B0X2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

470934:EGO56 RS02475
gene id: 470934:EGO56_RS02475
uniprot id: A0A7Z1Y0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS12755
gene id: 470934:EGO56_RS12755
uniprot id: A0A0X8Q5P2
names: Similarity
messages: Belongs to the UPF0434 family.

470934:EGO56 RS05735
gene id: 470934:EGO56_RS05735
uniprot id: A0A7Z1Y2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

470934:EGO56 RS12600
gene id: 470934:EGO56_RS12600
uniprot id: A0A1W9EYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

470934:EGO56 RS10665
gene id: 470934:EGO56_RS10665
uniprot id: A0A7Z2B1F3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

470934:EGO56 RS00285
gene id: 470934:EGO56_RS00285
uniprot id: A0A2R4J3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

470934:EGO56 RS16815
gene id: 470934:EGO56_RS16815
uniprot id: A0A7Z1Y5J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

470934:EGO56 RS11065
gene id: 470934:EGO56_RS11065
uniprot id: A0A7Z2B421
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

470934:EGO56 RS19865
gene id: 470934:EGO56_RS19865
uniprot id: A0A7Z1Y700
names: Similarity
messages: Belongs to the HAM1 NTPase family.

470934:EGO56 RS00240
gene id: 470934:EGO56_RS00240
uniprot id: A0A7U4Q4V5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS02285
gene id: 470934:EGO56_RS02285
uniprot id: A0A0X8QAF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

470934:EGO56 RS14025
gene id: 470934:EGO56_RS14025
uniprot id: A0A7Z1Y4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS02480
gene id: 470934:EGO56_RS02480
uniprot id: A0A7U4TCZ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

470934:EGO56 RS18305
gene id: 470934:EGO56_RS18305
uniprot id: A0A7U4TAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

470934:EGO56 RS01785
gene id: 470934:EGO56_RS01785
uniprot id: A0A7Z1Y0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03330
gene id: 470934:EGO56_RS03330
uniprot id: A0A7Z2AYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS17350
gene id: 470934:EGO56_RS17350
uniprot id: A0A7Z1Y6S8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

470934:EGO56 RS11825
gene id: 470934:EGO56_RS11825
uniprot id: A0A501SHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

470934:EGO56 RS14445
gene id: 470934:EGO56_RS14445
uniprot id: A0A7U5TXD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

470934:EGO56 RS03615
gene id: 470934:EGO56_RS03615
uniprot id: A0A109YBZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

470934:EGO56 RS01155
gene id: 470934:EGO56_RS01155
uniprot id: A0A7U4Q4K5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS05280
gene id: 470934:EGO56_RS05280
uniprot id: A0A7Z1Y1L2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

470934:EGO56 RS14725
gene id: 470934:EGO56_RS14725
uniprot id: A0A7Z2B0M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

470934:EGO56 RS00910
gene id: 470934:EGO56_RS00910
uniprot id: A0A7Z2B0T5
names: Similarity
messages: Belongs to the FBPase class 2 family.

470934:EGO56 RS15420
gene id: 470934:EGO56_RS15420
uniprot id: A0A7Z1Y529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

470934:EGO56 RS02510
gene id: 470934:EGO56_RS02510
uniprot id: A0A7Z2B198
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

470934:EGO56 RS06565
gene id: 470934:EGO56_RS06565
uniprot id: A0A7Z1Y275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

470934:EGO56 RS12880
gene id: 470934:EGO56_RS12880
uniprot id: A0A0X8Q6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

470934:EGO56 RS14360
gene id: 470934:EGO56_RS14360
uniprot id: A0A7Z1Y4P4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

470934:EGO56 RS02485
gene id: 470934:EGO56_RS02485
uniprot id: A0A0U3U6B1
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

470934:EGO56 RS04310
gene id: 470934:EGO56_RS04310
uniprot id: A0A7U4Q9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

470934:EGO56 RS11410
gene id: 470934:EGO56_RS11410
uniprot id: A0A7Z2B2S8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS04265
gene id: 470934:EGO56_RS04265
uniprot id: A0A7Z1Y194
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

470934:EGO56 RS02350
gene id: 470934:EGO56_RS02350
uniprot id: A0A1W9EMP0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

470934:EGO56 RS03990
gene id: 470934:EGO56_RS03990
uniprot id: A0A7Z1Y266
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

470934:EGO56 RS14750
gene id: 470934:EGO56_RS14750
uniprot id: A0A7U4TAX1
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS09045
gene id: 470934:EGO56_RS09045
uniprot id: A0A7Z1Y353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS13540
gene id: 470934:EGO56_RS13540
uniprot id: A0A7Z2B4G2
names: Similarity
messages: Belongs to the ModE family.

470934:EGO56 RS18430
gene id: 470934:EGO56_RS18430
uniprot id: A0A7Z1Y748
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

470934:EGO56 RS11745
gene id: 470934:EGO56_RS11745
uniprot id: A0A0X8Q601
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

470934:EGO56 RS02310
gene id: 470934:EGO56_RS02310
uniprot id: A0A0X8Q9G4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

470934:EGO56 RS10610
gene id: 470934:EGO56_RS10610
uniprot id: A0A7Z1Y3Q2
names: Similarity
messages: Belongs to the SufE family.

470934:EGO56 RS17015
gene id: 470934:EGO56_RS17015
uniprot id: A0A7Z2B3P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

470934:EGO56 RS00480
gene id: 470934:EGO56_RS00480
uniprot id: A0A5K4Z0Q8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

470934:EGO56 RS05600
gene id: 470934:EGO56_RS05600
uniprot id: A0A7Z2B1K6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

470934:EGO56 RS15050
gene id: 470934:EGO56_RS15050
uniprot id: A0A7Z2B282
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

470934:EGO56 RS02135
gene id: 470934:EGO56_RS02135
uniprot id: A0A7Z1Y0G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

470934:EGO56 RS07575
gene id: 470934:EGO56_RS07575
uniprot id: A0A7U4Q8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

470934:EGO56 RS17780
gene id: 470934:EGO56_RS17780
uniprot id: A0A7Z1Y6E8
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

470934:EGO56 RS03215
gene id: 470934:EGO56_RS03215
uniprot id: A0A7U4QA47
names: Similarity
messages: Belongs to the UPF0441 family.

470934:EGO56 RS16055
gene id: 470934:EGO56_RS16055
uniprot id: A0A7Z1Y5F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

470934:EGO56 RS02325
gene id: 470934:EGO56_RS02325
uniprot id: A0A0X8Q9H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

470934:EGO56 RS09210
gene id: 470934:EGO56_RS09210
uniprot id: A0A7Z1Y379
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

470934:EGO56 RS08470
gene id: 470934:EGO56_RS08470
uniprot id: A0A501SJD1
names: Similarity
messages: Belongs to the RutC family.

470934:EGO56 RS12665
gene id: 470934:EGO56_RS12665
uniprot id: A0A7Z1Y461
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

470934:EGO56 RS15325
gene id: 470934:EGO56_RS15325
uniprot id: A0A7Z1Y512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

470934:EGO56 RS20240
gene id: 470934:EGO56_RS20240
uniprot id: A0A0X8Q2F0
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS00695
gene id: 470934:EGO56_RS00695
uniprot id: A0A7Z2AZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

470934:EGO56 RS01210
gene id: 470934:EGO56_RS01210
uniprot id: A0A7U4Q4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

470934:EGO56 RS03765
gene id: 470934:EGO56_RS03765
uniprot id: A0A7Z1Y116
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

470934:EGO56 RS02490
gene id: 470934:EGO56_RS02490
uniprot id: A0A7Z1Y107
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

470934:EGO56 RS03710
gene id: 470934:EGO56_RS03710
uniprot id: A0A7Z1Y1F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

470934:EGO56 RS17320
gene id: 470934:EGO56_RS17320
uniprot id: A0A7Z2B536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

470934:EGO56 RS03725
gene id: 470934:EGO56_RS03725
uniprot id: A0A7Z2B1B4
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

470934:EGO56 RS16930
gene id: 470934:EGO56_RS16930
uniprot id: A0A7U4TA98
names: Similarity
messages: Belongs to the peptidase C56 family.

470934:EGO56 RS10825
gene id: 470934:EGO56_RS10825
uniprot id: A0A7Z2B1G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

470934:EGO56 RS05360
gene id: 470934:EGO56_RS05360
uniprot id: A0A7Z1Y1M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

470934:EGO56 RS13565
gene id: 470934:EGO56_RS13565
uniprot id: A0A0X8Q5B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

470934:EGO56 RS18200
gene id: 470934:EGO56_RS18200
uniprot id: A0A7Z1Y616
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

470934:EGO56 RS12690
gene id: 470934:EGO56_RS12690
uniprot id: A0A7Z1Y4G1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS05980
gene id: 470934:EGO56_RS05980
uniprot id: A0A7Z1Y2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS18895
gene id: 470934:EGO56_RS18895
uniprot id: A0A0X8Q373
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

470934:EGO56 RS00845
gene id: 470934:EGO56_RS00845
uniprot id: A0A7Z2AY95
names: Subcellular Location Annotation
messages: Cell inner membrane

470934:EGO56 RS07395
gene id: 470934:EGO56_RS07395
uniprot id: A0A7Z2B0V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS01390
gene id: 470934:EGO56_RS01390
uniprot id: A0A7Z1Y0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

470934:EGO56 RS08150
gene id: 470934:EGO56_RS08150
uniprot id: A0A7U4Q8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

470934:EGO56 RS15480
gene id: 470934:EGO56_RS15480
uniprot id: A0A7Z1Y533
names: Similarity
messages: Belongs to the CdaR family.

470934:EGO56 RS14610
gene id: 470934:EGO56_RS14610
uniprot id: A0A7Z1Y4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

470934:EGO56 RS11835
gene id: 470934:EGO56_RS11835
uniprot id: A0A7U4Q763
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

470934:EGO56 RS06280
gene id: 470934:EGO56_RS06280
uniprot id: A0A7Z2B0P5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

470934:EGO56 RS04235
gene id: 470934:EGO56_RS04235
uniprot id: A0A2R4JB98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS12985
gene id: 470934:EGO56_RS12985
uniprot id: A0A7Z1Y4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

470934:EGO56 RS00080
gene id: 470934:EGO56_RS00080
uniprot id: A0A7U4TA27
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

470934:EGO56 RS20455
gene id: 470934:EGO56_RS20455
uniprot id: A0A7Z1Y7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

470934:EGO56 RS15510
gene id: 470934:EGO56_RS15510
uniprot id: A0A2R4J582
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

470934:EGO56 RS22260
gene id: 470934:EGO56_RS22260
uniprot id: A0A501SD93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

470934:EGO56 RS16720
gene id: 470934:EGO56_RS16720
uniprot id: A0A7Z1Y5K5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

470934:EGO56 RS15870
gene id: 470934:EGO56_RS15870
uniprot id: A0A7Z2B2D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS09980
gene id: 470934:EGO56_RS09980
uniprot id: A0A7Z1Y372
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

470934:EGO56 RS18900
gene id: 470934:EGO56_RS18900
uniprot id: A0A1W9EQI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

470934:EGO56 RS08580
gene id: 470934:EGO56_RS08580
uniprot id: A0A7Z2B3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

470934:EGO56 RS15860
gene id: 470934:EGO56_RS15860
uniprot id: A0A2R4J521
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

470934:EGO56 RS09940
gene id: 470934:EGO56_RS09940
uniprot id: A0A7Z1Y3H1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

470934:EGO56 RS08930
gene id: 470934:EGO56_RS08930
uniprot id: A0A7Z1Y2U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

470934:EGO56 RS10265
gene id: 470934:EGO56_RS10265
uniprot id: A0A7Z1Y3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

470934:EGO56 RS05740
gene id: 470934:EGO56_RS05740
uniprot id: A0A7Z1Y1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

470934:EGO56 RS15070
gene id: 470934:EGO56_RS15070
uniprot id: A0A2R4J5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

470934:EGO56 RS15175
gene id: 470934:EGO56_RS15175
uniprot id: A0A7Z1Y5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS17245
gene id: 470934:EGO56_RS17245
uniprot id: A0A7U4T9J6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

470934:EGO56 RS02060
gene id: 470934:EGO56_RS02060
uniprot id: A0A7Z1Y0F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

470934:EGO56 RS13635
gene id: 470934:EGO56_RS13635
uniprot id: A0A7U4Q6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

470934:EGO56 RS15805
gene id: 470934:EGO56_RS15805
uniprot id: A0A7U4Q5Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

470934:EGO56 RS01175
gene id: 470934:EGO56_RS01175
uniprot id: A0A7Z2B0Z3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

470934:EGO56 RS02690
gene id: 470934:EGO56_RS02690
uniprot id: A0A7Z2AZZ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

470934:EGO56 RS13910
gene id: 470934:EGO56_RS13910
uniprot id: A0A2R4J5Y9
names: Similarity
messages: Belongs to the PhoH family.

470934:EGO56 RS05905
gene id: 470934:EGO56_RS05905
uniprot id: A0A0X8Q931
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS17240
gene id: 470934:EGO56_RS17240
uniprot id: A0A7Z1Y678
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

470934:EGO56 RS14755
gene id: 470934:EGO56_RS14755
uniprot id: A0A7U4Q6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

470934:EGO56 RS09030
gene id: 470934:EGO56_RS09030
uniprot id: A0A7Z1Y2V6
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

470934:EGO56 RS15790
gene id: 470934:EGO56_RS15790
uniprot id: A0A7Z2B0U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

470934:EGO56 RS15435
gene id: 470934:EGO56_RS15435
uniprot id: A0A7Z1Y5L6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS11040
gene id: 470934:EGO56_RS11040
uniprot id: A0A7U4Q7H8
names: Similarity
messages: Belongs to the UPF0162 family.

470934:EGO56 RS11750
gene id: 470934:EGO56_RS11750
uniprot id: A0A7Z1Y4U7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

470934:EGO56 RS17080
gene id: 470934:EGO56_RS17080
uniprot id: A0A7Z1Y618
names: Similarity
messages: Belongs to the peptidase S13 family.

470934:EGO56 RS07040
gene id: 470934:EGO56_RS07040
uniprot id: A0A7Z1Y270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS03200
gene id: 470934:EGO56_RS03200
uniprot id: A0A7Z1Y0U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

470934:EGO56 RS15750
gene id: 470934:EGO56_RS15750
uniprot id: A0A7Z1Y567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

470934:EGO56 RS14615
gene id: 470934:EGO56_RS14615
uniprot id: A0A0X8Q636
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

470934:EGO56 RS11805
gene id: 470934:EGO56_RS11805
uniprot id: A0A7Z2B2P6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

470934:EGO56 RS03870
gene id: 470934:EGO56_RS03870
uniprot id: A0A7U4TBU2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

470934:EGO56 RS04670
gene id: 470934:EGO56_RS04670
uniprot id: A0A7Z2AYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS04275
gene id: 470934:EGO56_RS04275
uniprot id: A0A7Z1Y6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

470934:EGO56 RS15800
gene id: 470934:EGO56_RS15800
uniprot id: A0A7Z1Y592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

470934:EGO56 RS17010
gene id: 470934:EGO56_RS17010
uniprot id: A0A2R4J4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

470934:EGO56 RS15030
gene id: 470934:EGO56_RS15030
uniprot id: A0A7Z2B4P7
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

470934:EGO56 RS20305
gene id: 470934:EGO56_RS20305
uniprot id: A0A7Z2B5S4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

470934:EGO56 RS14340
gene id: 470934:EGO56_RS14340
uniprot id: A0A7Z2B235
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

470934:EGO56 RS08300
gene id: 470934:EGO56_RS08300
uniprot id: A0A7Z1Y3L6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

470934:EGO56 RS14345
gene id: 470934:EGO56_RS14345
uniprot id: A0A7Z1Y6R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS08160
gene id: 470934:EGO56_RS08160
uniprot id: A0A2R4J987
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

470934:EGO56 RS06050
gene id: 470934:EGO56_RS06050
uniprot id: A0A7Z1Y1T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

470934:EGO56 RS08410
gene id: 470934:EGO56_RS08410
uniprot id: A0A109YBE4
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS13350
gene id: 470934:EGO56_RS13350
uniprot id: A0A7Z1Y4D4
names: Similarity
messages: Belongs to the peptidase S11 family.

470934:EGO56 RS11735
gene id: 470934:EGO56_RS11735
uniprot id: A0A7Z2B042
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

470934:EGO56 RS14830
gene id: 470934:EGO56_RS14830
uniprot id: A0A7Z1Y500
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

470934:EGO56 RS10570
gene id: 470934:EGO56_RS10570
uniprot id: A0A7Z1Y3F4
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

470934:EGO56 RS05190
gene id: 470934:EGO56_RS05190
uniprot id: A0A7Z1Y1H9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

470934:EGO56 RS18380
gene id: 470934:EGO56_RS18380
uniprot id: A0A7Z1Y637
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

470934:EGO56 RS16000
gene id: 470934:EGO56_RS16000
uniprot id: A0A7Z1Y5U8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

470934:EGO56 RS15495
gene id: 470934:EGO56_RS15495
uniprot id: A0A7Z1Y593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

470934:EGO56 RS09985
gene id: 470934:EGO56_RS09985
uniprot id: A0A7Z1Y465
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

470934:EGO56 RS04165
gene id: 470934:EGO56_RS04165
uniprot id: A0A7Z1Y282
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

470934:EGO56 RS03530
gene id: 470934:EGO56_RS03530
uniprot id: A0A7Z1Y139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

470934:EGO56 RS05835
gene id: 470934:EGO56_RS05835
uniprot id: A0A7Z1Y1S3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

470934:EGO56 RS03005
gene id: 470934:EGO56_RS03005
uniprot id: A0A2R4JC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS01135
gene id: 470934:EGO56_RS01135
uniprot id: A0A7Z1Y038
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS18090
gene id: 470934:EGO56_RS18090
uniprot id: A0A7Z1Y617
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

470934:EGO56 RS12560
gene id: 470934:EGO56_RS12560
uniprot id: A0A7Z2B1S9
names: Subcellular Location Annotation
messages: Cell inner membrane

470934:EGO56 RS07035
gene id: 470934:EGO56_RS07035
uniprot id: A0A7Z1Y2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

470934:EGO56 RS06025
gene id: 470934:EGO56_RS06025
uniprot id: A0A1W9EVA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

470934:EGO56 RS02355
gene id: 470934:EGO56_RS02355
uniprot id: A0A0X8Q9G3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

470934:EGO56 RS02150
gene id: 470934:EGO56_RS02150
uniprot id: A0A7Z1Y0I6
names: Similarity
messages: Belongs to the SlyX family.

470934:EGO56 RS20310
gene id: 470934:EGO56_RS20310
uniprot id: A0A7Z2B4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

470934:EGO56 RS11645
gene id: 470934:EGO56_RS11645
uniprot id: A0A7Z2B2N4
names: Similarity
messages: Belongs to the UPF0227 family.

470934:EGO56 RS02800
gene id: 470934:EGO56_RS02800
uniprot id: A0A7Z1Y0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

470934:EGO56 RS14600
gene id: 470934:EGO56_RS14600
uniprot id: A0A7Z1Y4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

470934:EGO56 RS02930
gene id: 470934:EGO56_RS02930
uniprot id: A0A7Z1Y0R7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS17230
gene id: 470934:EGO56_RS17230
uniprot id: A0A7Z1Y639
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

470934:EGO56 RS13795
gene id: 470934:EGO56_RS13795
uniprot id: A0A7Z2B4H7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

470934:EGO56 RS13195
gene id: 470934:EGO56_RS13195
uniprot id: A0A7Z1Y5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

470934:EGO56 RS08510
gene id: 470934:EGO56_RS08510
uniprot id: A0A0X8Q765
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

470934:EGO56 RS02695
gene id: 470934:EGO56_RS02695
uniprot id: A0A7Z1Y0N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

470934:EGO56 RS03295
gene id: 470934:EGO56_RS03295
uniprot id: A0A7Z1Y0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS05615
gene id: 470934:EGO56_RS05615
uniprot id: A0A7U4Q9F2
names: Similarity
messages: Belongs to the universal stress protein A family.

470934:EGO56 RS01830
gene id: 470934:EGO56_RS01830
uniprot id: A0A7Z1Y0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

470934:EGO56 RS05890
gene id: 470934:EGO56_RS05890
uniprot id: A0A7Z2B0L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

470934:EGO56 RS00555
gene id: 470934:EGO56_RS00555
uniprot id: A0A7Z1XZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

470934:EGO56 RS13665
gene id: 470934:EGO56_RS13665
uniprot id: A0A7Z2B1Z8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

470934:EGO56 RS04205
gene id: 470934:EGO56_RS04205
uniprot id: A0A7Z1Y1L9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS04905
gene id: 470934:EGO56_RS04905
uniprot id: A0A7Z1Y1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

470934:EGO56 RS08545
gene id: 470934:EGO56_RS08545
uniprot id: A0A7Z1Y2U4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

470934:EGO56 RS12020
gene id: 470934:EGO56_RS12020
uniprot id: A0A7Z1Y3Y6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

470934:EGO56 RS15680
gene id: 470934:EGO56_RS15680
uniprot id: A0A7Z1Y7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

470934:EGO56 RS12885
gene id: 470934:EGO56_RS12885
uniprot id: A0A7Z1Y595
names: Similarity
messages: Belongs to the ClpA/ClpB family.

470934:EGO56 RS06200
gene id: 470934:EGO56_RS06200
uniprot id: A0A7Z2B0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

470934:EGO56 RS13935
gene id: 470934:EGO56_RS13935
uniprot id: A0A7Z1Y5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS20460
gene id: 470934:EGO56_RS20460
uniprot id: A0A7Z1Y7E1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

470934:EGO56 RS11030
gene id: 470934:EGO56_RS11030
uniprot id: A0A7U4Q7I8
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS00590
gene id: 470934:EGO56_RS00590
uniprot id: A0A7Z2B275
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).
messages: Cell inner membrane

470934:EGO56 RS03410
gene id: 470934:EGO56_RS03410
uniprot id: A0A7Z2AYQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

470934:EGO56 RS01595
gene id: 470934:EGO56_RS01595
uniprot id: A0A7U4QAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

470934:EGO56 RS10810
gene id: 470934:EGO56_RS10810
uniprot id: A0A7Z2B2H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

470934:EGO56 RS18890
gene id: 470934:EGO56_RS18890
uniprot id: A0A1W9EQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

470934:EGO56 RS02320
gene id: 470934:EGO56_RS02320
uniprot id: A0A1W9EMQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS01550
gene id: 470934:EGO56_RS01550
uniprot id: A0A7Z1Y0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

470934:EGO56 RS02295
gene id: 470934:EGO56_RS02295
uniprot id: A0A0X8Q9V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

470934:EGO56 RS02145
gene id: 470934:EGO56_RS02145
uniprot id: A0A7Z1Y0L4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

470934:EGO56 RS14315
gene id: 470934:EGO56_RS14315
uniprot id: A0A7Z1Y519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

470934:EGO56 RS11830
gene id: 470934:EGO56_RS11830
uniprot id: A0A7U4TBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

470934:EGO56 RS18060
gene id: 470934:EGO56_RS18060
uniprot id: A0A7Z2B175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

470934:EGO56 RS13095
gene id: 470934:EGO56_RS13095
uniprot id: A0A7U4Q6Z9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS05435
gene id: 470934:EGO56_RS05435
uniprot id: A0A7Z1Y1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

470934:EGO56 RS02705
gene id: 470934:EGO56_RS02705
uniprot id: A0A7Z1Y0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

470934:EGO56 RS00275
gene id: 470934:EGO56_RS00275
uniprot id: A0A2R4J3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

470934:EGO56 RS00940
gene id: 470934:EGO56_RS00940
uniprot id: A0A2R4J308
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

470934:EGO56 RS00930
gene id: 470934:EGO56_RS00930
uniprot id: A0A7Z1Y012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

470934:EGO56 RS05970
gene id: 470934:EGO56_RS05970
uniprot id: A0A7Z1Y6D2
names: Similarity
messages: Belongs to the UPF0304 family.

470934:EGO56 RS15890
gene id: 470934:EGO56_RS15890
uniprot id: A0A0X8Q4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

470934:EGO56 RS07840
gene id: 470934:EGO56_RS07840
uniprot id: A0A7Z1Y2N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

470934:EGO56 RS16775
gene id: 470934:EGO56_RS16775
uniprot id: A0A7Z2B2I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

470934:EGO56 RS12895
gene id: 470934:EGO56_RS12895
uniprot id: A0A7U4Q6W2
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS07130
gene id: 470934:EGO56_RS07130
uniprot id: A0A7U4TC90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS05770
gene id: 470934:EGO56_RS05770
uniprot id: A0A7U4TCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

470934:EGO56 RS03705
gene id: 470934:EGO56_RS03705
uniprot id: A0A7Z1Y189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

470934:EGO56 RS03285
gene id: 470934:EGO56_RS03285
uniprot id: A0A7Z1Y0W1
names: Subunit
messages: Monomer.

470934:EGO56 RS09515
gene id: 470934:EGO56_RS09515
uniprot id: A0A7Z1Y374
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

470934:EGO56 RS20580
gene id: 470934:EGO56_RS20580
uniprot id: A0A7Z1Y7K0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

470934:EGO56 RS02855
gene id: 470934:EGO56_RS02855
uniprot id: A0A7Z1Y1T1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

470934:EGO56 RS21955
gene id: 470934:EGO56_RS21955
uniprot id: A0A7Z1Y7Q3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

470934:EGO56 RS05910
gene id: 470934:EGO56_RS05910
uniprot id: A0A7Z1Y1Q3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS03325
gene id: 470934:EGO56_RS03325
uniprot id: A0A7Z2B1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

470934:EGO56 RS17180
gene id: 470934:EGO56_RS17180
uniprot id: A0A7Z2B3Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS18515
gene id: 470934:EGO56_RS18515
uniprot id: A0A2R4J3N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

470934:EGO56 RS03890
gene id: 470934:EGO56_RS03890
uniprot id: A0A7Z2B1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

470934:EGO56 RS00870
gene id: 470934:EGO56_RS00870
uniprot id: A0A0X8Q3J6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

470934:EGO56 RS17800
gene id: 470934:EGO56_RS17800
uniprot id: A0A7U4Q566
names: Similarity
messages: Belongs to the UPF0047 family.

470934:EGO56 RS01040
gene id: 470934:EGO56_RS01040
uniprot id: A0A7Z1Y0A1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

470934:EGO56 RS11540
gene id: 470934:EGO56_RS11540
uniprot id: A0A7Z1Y3S2
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

470934:EGO56 RS16410
gene id: 470934:EGO56_RS16410
uniprot id: A0A7Z1Y5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS13655
gene id: 470934:EGO56_RS13655
uniprot id: A0A7Z1Y7J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

470934:EGO56 RS02280
gene id: 470934:EGO56_RS02280
uniprot id: A0A109YC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS14835
gene id: 470934:EGO56_RS14835
uniprot id: A0A7U4TAW6
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

470934:EGO56 RS05730
gene id: 470934:EGO56_RS05730
uniprot id: A0A7Z1Y1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

470934:EGO56 RS06205
gene id: 470934:EGO56_RS06205
uniprot id: A0A7U4Q931
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

470934:EGO56 RS09255
gene id: 470934:EGO56_RS09255
uniprot id: A0A7Z1Y3Y3
names: Subcellular Location Annotation
messages: Cell inner membrane

470934:EGO56 RS04130
gene id: 470934:EGO56_RS04130
uniprot id: A0A7Z1Y1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

470934:EGO56 RS18865
gene id: 470934:EGO56_RS18865
uniprot id: A0A7Z1Y6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03995
gene id: 470934:EGO56_RS03995
uniprot id: A0A7Z1Y1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

470934:EGO56 RS00840
gene id: 470934:EGO56_RS00840
uniprot id: A0A7Z2B0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

470934:EGO56 RS13940
gene id: 470934:EGO56_RS13940
uniprot id: A0A7Z1Y4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS05045
gene id: 470934:EGO56_RS05045
uniprot id: A0A7Z1Y1I6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

470934:EGO56 RS00005
gene id: 470934:EGO56_RS00005
uniprot id: A0A7Z1XZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

470934:EGO56 RS12595
gene id: 470934:EGO56_RS12595
uniprot id: A0A2R4J6M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

470934:EGO56 RS01980
gene id: 470934:EGO56_RS01980
uniprot id: A0A0X8Q9U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

470934:EGO56 RS04800
gene id: 470934:EGO56_RS04800
uniprot id: A0A7Z1Y1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

470934:EGO56 RS04885
gene id: 470934:EGO56_RS04885
uniprot id: A0A7Z1Y1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

470934:EGO56 RS02520
gene id: 470934:EGO56_RS02520
uniprot id: A0A7Z1Y6B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

470934:EGO56 RS18485
gene id: 470934:EGO56_RS18485
uniprot id: A0A7Z1Y6E4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

470934:EGO56 RS18780
gene id: 470934:EGO56_RS18780
uniprot id: A0A7Z1Y691
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

470934:EGO56 RS14695
gene id: 470934:EGO56_RS14695
uniprot id: A0A7Z1Y586
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

470934:EGO56 RS14630
gene id: 470934:EGO56_RS14630
uniprot id: A0A7Z1Y563
names: Similarity
messages: Belongs to the UPF0234 family.

470934:EGO56 RS08125
gene id: 470934:EGO56_RS08125
uniprot id: A0A7Z1Y3I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

470934:EGO56 RS18105
gene id: 470934:EGO56_RS18105
uniprot id: A0A7Z1Y6F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

470934:EGO56 RS04835
gene id: 470934:EGO56_RS04835
uniprot id: A0A7U4TCT2
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

470934:EGO56 RS15565
gene id: 470934:EGO56_RS15565
uniprot id: A0A2R4J572
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

470934:EGO56 RS13645
gene id: 470934:EGO56_RS13645
uniprot id: A0A7U4Q6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

470934:EGO56 RS00875
gene id: 470934:EGO56_RS00875
uniprot id: A0A7Z1Y005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

470934:EGO56 RS18580
gene id: 470934:EGO56_RS18580
uniprot id: A0A7Z2B598
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

470934:EGO56 RS00490
gene id: 470934:EGO56_RS00490
uniprot id: A0A7Z1XZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

470934:EGO56 RS18365
gene id: 470934:EGO56_RS18365
uniprot id: A0A7Z1Y644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

470934:EGO56 RS14710
gene id: 470934:EGO56_RS14710
uniprot id: A0A7U4Q6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

470934:EGO56 RS09305
gene id: 470934:EGO56_RS09305
uniprot id: A0A2R4J8P4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS10575
gene id: 470934:EGO56_RS10575
uniprot id: A0A7Z1Y3J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

470934:EGO56 RS06195
gene id: 470934:EGO56_RS06195
uniprot id: A0A109YCD8
names: Similarity
messages: Belongs to the UPF0352 family.

470934:EGO56 RS00720
gene id: 470934:EGO56_RS00720
uniprot id: A0A0X8Q3M0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

470934:EGO56 RS17295
gene id: 470934:EGO56_RS17295
uniprot id: A0A2R4J497
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

470934:EGO56 RS15185
gene id: 470934:EGO56_RS15185
uniprot id: A0A7Z2B3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS13975
gene id: 470934:EGO56_RS13975
uniprot id: A0A7Z1Y4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

470934:EGO56 RS03755
gene id: 470934:EGO56_RS03755
uniprot id: A0A7Z1Y186
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

470934:EGO56 RS02300
gene id: 470934:EGO56_RS02300
uniprot id: A0A7Z1Y0K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

470934:EGO56 RS15330
gene id: 470934:EGO56_RS15330
uniprot id: A0A7Z1Y557
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

470934:EGO56 RS14585
gene id: 470934:EGO56_RS14585
uniprot id: A0A7Z1Y4V0
names: Similarity
messages: Belongs to the BolA/IbaG family.

470934:EGO56 RS00235
gene id: 470934:EGO56_RS00235
uniprot id: A0A7Z1XZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

470934:EGO56 RS04955
gene id: 470934:EGO56_RS04955
uniprot id: A0A0X8Q8F5
names: Similarity
messages: Belongs to the P(II) protein family.

470934:EGO56 RS17930
gene id: 470934:EGO56_RS17930
uniprot id: A0A7Z1Y6C9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

470934:EGO56 RS15850
gene id: 470934:EGO56_RS15850
uniprot id: A0A7Z2B4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

470934:EGO56 RS00995
gene id: 470934:EGO56_RS00995
uniprot id: A0A7Z2AYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

470934:EGO56 RS16175
gene id: 470934:EGO56_RS16175
uniprot id: A0A7Z2B0W4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

470934:EGO56 RS17820
gene id: 470934:EGO56_RS17820
uniprot id: A0A7Z1Y6Y3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

470934:EGO56 RS00820
gene id: 470934:EGO56_RS00820
uniprot id: A0A2R4J393
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

470934:EGO56 RS01685
gene id: 470934:EGO56_RS01685
uniprot id: A0A7Z1Y0B0
names: Similarity
messages: Belongs to the pirin family.

470934:EGO56 RS02000
gene id: 470934:EGO56_RS02000
uniprot id: A0A7Z1Y0H0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

470934:EGO56 RS06865
gene id: 470934:EGO56_RS06865
uniprot id: A0A0X8Q7Q3
names: Similarity
messages: Belongs to the UPF0265 family.

470934:EGO56 RS09690
gene id: 470934:EGO56_RS09690
uniprot id: A0A7Z1Y3F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

470934:EGO56 RS17915
gene id: 470934:EGO56_RS17915
uniprot id: A0A7Z1Y5Z6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS00445
gene id: 470934:EGO56_RS00445
uniprot id: A0A7U4TA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

470934:EGO56 RS05310
gene id: 470934:EGO56_RS05310
uniprot id: A0A7Z2B310
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

470934:EGO56 RS16290
gene id: 470934:EGO56_RS16290
uniprot id: A0A7Z1Y5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

470934:EGO56 RS04615
gene id: 470934:EGO56_RS04615
uniprot id: A0A7Z1Y1B5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

470934:EGO56 RS11840
gene id: 470934:EGO56_RS11840
uniprot id: A0A7Z1Y400
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

470934:EGO56 RS08200
gene id: 470934:EGO56_RS08200
uniprot id: A0A7Z1Y3J8
names: Similarity
messages: Belongs to the pyruvate kinase family.

470934:EGO56 RS15410
gene id: 470934:EGO56_RS15410
uniprot id: A0A2R4J5A1
names: Similarity
messages: Belongs to the skp family.

470934:EGO56 RS16710
gene id: 470934:EGO56_RS16710
uniprot id: A0A7Z1Y5I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

470934:EGO56 RS08700
gene id: 470934:EGO56_RS08700
uniprot id: A0A7U4Q896
names: Similarity
messages: Belongs to the UDPGP type 2 family.

470934:EGO56 RS13690
gene id: 470934:EGO56_RS13690
uniprot id: A0A7Z1Y4H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

470934:EGO56 RS18400
gene id: 470934:EGO56_RS18400
uniprot id: A0A7Z2B589
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS06215
gene id: 470934:EGO56_RS06215
uniprot id: A0A7Z1Y207
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

470934:EGO56 RS02775
gene id: 470934:EGO56_RS02775
uniprot id: A0A0U3U4B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

470934:EGO56 RS11785
gene id: 470934:EGO56_RS11785
uniprot id: A0A7Z1Y448
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

470934:EGO56 RS08520
gene id: 470934:EGO56_RS08520
uniprot id: A0A7U4Q8C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

470934:EGO56 RS10725
gene id: 470934:EGO56_RS10725
uniprot id: A0A0X8Q6N0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

470934:EGO56 RS13725
gene id: 470934:EGO56_RS13725
uniprot id: A0A7Z2B318
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

470934:EGO56 RS06000
gene id: 470934:EGO56_RS06000
uniprot id: A0A7Z1Y1T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS14415
gene id: 470934:EGO56_RS14415
uniprot id: A0A7Z2B0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

470934:EGO56 RS17165
gene id: 470934:EGO56_RS17165
uniprot id: A0A0X8Q520
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

470934:EGO56 RS14000
gene id: 470934:EGO56_RS14000
uniprot id: A0A7Z2B0H8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

470934:EGO56 RS15445
gene id: 470934:EGO56_RS15445
uniprot id: A0A7Z2B3C0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS07610
gene id: 470934:EGO56_RS07610
uniprot id: A0A7Z1Y2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

470934:EGO56 RS00835
gene id: 470934:EGO56_RS00835
uniprot id: A0A7Z2B0S9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

470934:EGO56 RS21635
gene id: 470934:EGO56_RS21635
uniprot id: A0A7Z1Y7L7
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS02835
gene id: 470934:EGO56_RS02835
uniprot id: A0A0X8Q9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

470934:EGO56 RS05425
gene id: 470934:EGO56_RS05425
uniprot id: A0A7Z1Y1K4
names: Subcellular Location Annotation
messages: Cell inner membrane

470934:EGO56 RS13525
gene id: 470934:EGO56_RS13525
uniprot id: A0A7U4TAU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

470934:EGO56 RS05400
gene id: 470934:EGO56_RS05400
uniprot id: A0A7Z2AZ11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

470934:EGO56 RS13155
gene id: 470934:EGO56_RS13155
uniprot id: A0A7U4TBG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS13800
gene id: 470934:EGO56_RS13800
uniprot id: A0A7Z2B323
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

470934:EGO56 RS17925
gene id: 470934:EGO56_RS17925
uniprot id: A0A2R4J3Y1
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS20005
gene id: 470934:EGO56_RS20005
uniprot id: A0A7Z1Y702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS14865
gene id: 470934:EGO56_RS14865
uniprot id: A0A7Z2B4N8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

470934:EGO56 RS14005
gene id: 470934:EGO56_RS14005
uniprot id: A0A7Z2B220
names: Similarity
messages: Belongs to the UPF0250 family.

470934:EGO56 RS06355
gene id: 470934:EGO56_RS06355
uniprot id: A0A7Z2AZ68
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

470934:EGO56 RS10565
gene id: 470934:EGO56_RS10565
uniprot id: A0A7Z1Y4E7
names: Similarity
messages: Belongs to the CFA/CMAS family.

470934:EGO56 RS18670
gene id: 470934:EGO56_RS18670
uniprot id: A0A7Z2B3Z8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS00295
gene id: 470934:EGO56_RS00295
uniprot id: A0A0X8Q3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

470934:EGO56 RS05005
gene id: 470934:EGO56_RS05005
uniprot id: A0A7U4Q9N1
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

470934:EGO56 RS14570
gene id: 470934:EGO56_RS14570
uniprot id: A0A7Z2B3C3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

470934:EGO56 RS02185
gene id: 470934:EGO56_RS02185
uniprot id: A0A7U4QAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

470934:EGO56 RS15450
gene id: 470934:EGO56_RS15450
uniprot id: A0A7Z2B3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

470934:EGO56 RS13710
gene id: 470934:EGO56_RS13710
uniprot id: A0A7U4TAT1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

470934:EGO56 RS14650
gene id: 470934:EGO56_RS14650
uniprot id: A0A7Z2B0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

470934:EGO56 RS01630
gene id: 470934:EGO56_RS01630
uniprot id: A0A7Z1Y0Q1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS20145
gene id: 470934:EGO56_RS20145
uniprot id: A0A7Z2B4D9
names: Similarity
messages: Belongs to the Gfa family.

470934:EGO56 RS16010
gene id: 470934:EGO56_RS16010
uniprot id: A0A7Z2B3F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

470934:EGO56 RS02275
gene id: 470934:EGO56_RS02275
uniprot id: A0A0U3TEH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

470934:EGO56 RS00250
gene id: 470934:EGO56_RS00250
uniprot id: A0A7Z2B252
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

470934:EGO56 RS00350
gene id: 470934:EGO56_RS00350
uniprot id: A0A7Z1XZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

470934:EGO56 RS11820
gene id: 470934:EGO56_RS11820
uniprot id: A0A7Z2B1N4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

470934:EGO56 RS18845
gene id: 470934:EGO56_RS18845
uniprot id: A0A2R4J3I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

470934:EGO56 RS01725
gene id: 470934:EGO56_RS01725
uniprot id: A0A7Z2B146
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS14565
gene id: 470934:EGO56_RS14565
uniprot id: A0A2R4J5R3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

470934:EGO56 RS05950
gene id: 470934:EGO56_RS05950
uniprot id: A0A2R4JAD0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

470934:EGO56 RS02375
gene id: 470934:EGO56_RS02375
uniprot id: A0A7U4TCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

470934:EGO56 RS14875
gene id: 470934:EGO56_RS14875
uniprot id: A0A7Z2B438
names: Similarity
messages: Belongs to the UPF0178 family.

470934:EGO56 RS00925
gene id: 470934:EGO56_RS00925
uniprot id: A0A0X8Q487
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

470934:EGO56 RS05935
gene id: 470934:EGO56_RS05935
uniprot id: A0A7Z1Y223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS02765
gene id: 470934:EGO56_RS02765
uniprot id: A0A0X8Q9B2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

470934:EGO56 RS01500
gene id: 470934:EGO56_RS01500
uniprot id: A0A7Z2AYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

470934:EGO56 RS10275
gene id: 470934:EGO56_RS10275
uniprot id: A0A7Z1Y3L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

470934:EGO56 RS07160
gene id: 470934:EGO56_RS07160
uniprot id: A0A7Z2B0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS17075
gene id: 470934:EGO56_RS17075
uniprot id: A0A5K4YWI4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

470934:EGO56 RS04815
gene id: 470934:EGO56_RS04815
uniprot id: A0A7U4Q9L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

470934:EGO56 RS14365
gene id: 470934:EGO56_RS14365
uniprot id: A0A7Z1Y4U0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

470934:EGO56 RS01095
gene id: 470934:EGO56_RS01095
uniprot id: A0A7Z2B0U5
names: Similarity
messages: Belongs to the UPF0438 family.

470934:EGO56 RS05550
gene id: 470934:EGO56_RS05550
uniprot id: A0A7Z1Y1L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

470934:EGO56 RS06595
gene id: 470934:EGO56_RS06595
uniprot id: A0A7Z2AZ82
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

470934:EGO56 RS09190
gene id: 470934:EGO56_RS09190
uniprot id: A0A7Z1Y325
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

470934:EGO56 RS13820
gene id: 470934:EGO56_RS13820
uniprot id: A0A7Z1Y4K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS04300
gene id: 470934:EGO56_RS04300
uniprot id: A0A7U4Q9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

470934:EGO56 RS13920
gene id: 470934:EGO56_RS13920
uniprot id: A0A7U4Q6J3
names: Similarity
messages: Belongs to the UPF0053 family.

470934:EGO56 RS07560
gene id: 470934:EGO56_RS07560
uniprot id: A0A0X8Q7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

470934:EGO56 RS18885
gene id: 470934:EGO56_RS18885
uniprot id: A0A7Z1Y6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

470934:EGO56 RS13135
gene id: 470934:EGO56_RS13135
uniprot id: A0A7Z1Y4G2
names: Subcellular Location Annotation
messages: Cell outer membrane

470934:EGO56 RS17000
gene id: 470934:EGO56_RS17000
uniprot id: A0A0X8Q4N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

470934:EGO56 RS10830
gene id: 470934:EGO56_RS10830
uniprot id: A0A7Z1Y3I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

470934:EGO56 RS14390
gene id: 470934:EGO56_RS14390
uniprot id: A0A2R4J5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

470934:EGO56 RS16700
gene id: 470934:EGO56_RS16700
uniprot id: A0A7Z1Y5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

470934:EGO56 RS15985
gene id: 470934:EGO56_RS15985
uniprot id: A0A7Z1Y598
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

470934:EGO56 RS01410
gene id: 470934:EGO56_RS01410
uniprot id: A0A7Z2B120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

470934:EGO56 RS18245
gene id: 470934:EGO56_RS18245
uniprot id: A0A7Z2B3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

470934:EGO56 RS08120
gene id: 470934:EGO56_RS08120
uniprot id: A0A7Z1Y2J5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS15110
gene id: 470934:EGO56_RS15110
uniprot id: A0A7Z2B3A0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

470934:EGO56 RS07460
gene id: 470934:EGO56_RS07460
uniprot id: A0A7Z2B1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

470934:EGO56 RS00390
gene id: 470934:EGO56_RS00390
uniprot id: A0A7Z1Y0A6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

470934:EGO56 RS02330
gene id: 470934:EGO56_RS02330
uniprot id: A0A7Z2B190
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

470934:EGO56 RS14560
gene id: 470934:EGO56_RS14560
uniprot id: A0A2R4J5L3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

470934:EGO56 RS08860
gene id: 470934:EGO56_RS08860
uniprot id: A0A7Z1Y3T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

470934:EGO56 RS02255
gene id: 470934:EGO56_RS02255
uniprot id: A0A120LPQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS12785
gene id: 470934:EGO56_RS12785
uniprot id: A0A501SLQ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

470934:EGO56 RS18100
gene id: 470934:EGO56_RS18100
uniprot id: A0A0X8Q442
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

470934:EGO56 RS05800
gene id: 470934:EGO56_RS05800
uniprot id: A0A7Z2AZ32
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

470934:EGO56 RS07365
gene id: 470934:EGO56_RS07365
uniprot id: A0A7Z1Y2L7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS09240
gene id: 470934:EGO56_RS09240
uniprot id: A0A7U4Q877
names: Similarity
messages: Belongs to the peptidase S1B family.

470934:EGO56 RS07835
gene id: 470934:EGO56_RS07835
uniprot id: A0A7Z1Y2G2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

470934:EGO56 RS15610
gene id: 470934:EGO56_RS15610
uniprot id: A0A7Z2B3D2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS08165
gene id: 470934:EGO56_RS08165
uniprot id: A0A7Z1Y2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

470934:EGO56 RS05750
gene id: 470934:EGO56_RS05750
uniprot id: A0A7Z1Y1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

470934:EGO56 RS04450
gene id: 470934:EGO56_RS04450
uniprot id: A0A7Z1Y1B0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

470934:EGO56 RS00010
gene id: 470934:EGO56_RS00010
uniprot id: A0A7Z1Y059
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

470934:EGO56 RS04830
gene id: 470934:EGO56_RS04830
uniprot id: A0A7Z1Y1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

470934:EGO56 RS01825
gene id: 470934:EGO56_RS01825
uniprot id: A0A7Z1Y0K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

470934:EGO56 RS17065
gene id: 470934:EGO56_RS17065
uniprot id: A0A7Z1Y6K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

470934:EGO56 RS05380
gene id: 470934:EGO56_RS05380
uniprot id: A0A501SDS9
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

470934:EGO56 RS12970
gene id: 470934:EGO56_RS12970
uniprot id: A0A7Z1Y492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS15595
gene id: 470934:EGO56_RS15595
uniprot id: A0A7Z1Y5F8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

470934:EGO56 RS03040
gene id: 470934:EGO56_RS03040
uniprot id: A0A7U4QAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

470934:EGO56 RS13980
gene id: 470934:EGO56_RS13980
uniprot id: A0A0U3UGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

470934:EGO56 RS10900
gene id: 470934:EGO56_RS10900
uniprot id: A0A7Z2B2P8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS14020
gene id: 470934:EGO56_RS14020
uniprot id: A0A501SIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

470934:EGO56 RS08745
gene id: 470934:EGO56_RS08745
uniprot id: A0A7Z1Y334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS07845
gene id: 470934:EGO56_RS07845
uniprot id: A0A2R4J9D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

470934:EGO56 RS15725
gene id: 470934:EGO56_RS15725
uniprot id: A0A7Z1Y6I6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

470934:EGO56 RS01140
gene id: 470934:EGO56_RS01140
uniprot id: A0A7Z1Y088
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS12790
gene id: 470934:EGO56_RS12790
uniprot id: A0A7Z2B317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

470934:EGO56 RS13660
gene id: 470934:EGO56_RS13660
uniprot id: A0A2R4J618
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

470934:EGO56 RS02005
gene id: 470934:EGO56_RS02005
uniprot id: A0A7Z1Y0M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

470934:EGO56 RS17025
gene id: 470934:EGO56_RS17025
uniprot id: A0A501S7N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

470934:EGO56 RS14270
gene id: 470934:EGO56_RS14270
uniprot id: A0A7Z1Y5N2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

470934:EGO56 RS03650
gene id: 470934:EGO56_RS03650
uniprot id: A0A7Z2B1G2
names: Similarity
messages: Belongs to the YggT family.

470934:EGO56 RS14685
gene id: 470934:EGO56_RS14685
uniprot id: A0A7Z1Y501
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

470934:EGO56 RS08765
gene id: 470934:EGO56_RS08765
uniprot id: A0A0X8Q728
names: Similarity
messages: Belongs to the UPF0263 family.

470934:EGO56 RS05960
gene id: 470934:EGO56_RS05960
uniprot id: A0A7Z2AZ39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

470934:EGO56 RS02635
gene id: 470934:EGO56_RS02635
uniprot id: A0A7Z1Y0P6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

470934:EGO56 RS18050
gene id: 470934:EGO56_RS18050
uniprot id: A0A7Z2B3U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS07600
gene id: 470934:EGO56_RS07600
uniprot id: A0A7U4Q8K4
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS05155
gene id: 470934:EGO56_RS05155
uniprot id: A0A7Z2B1I8
names: Similarity
messages: Belongs to the GppA/Ppx family.

470934:EGO56 RS01815
gene id: 470934:EGO56_RS01815
uniprot id: A0A7Z1Y0C2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

470934:EGO56 RS07605
gene id: 470934:EGO56_RS07605
uniprot id: A0A7Z1Y2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

470934:EGO56 RS00905
gene id: 470934:EGO56_RS00905
uniprot id: A0A7Z2B294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS02290
gene id: 470934:EGO56_RS02290
uniprot id: A0A0X8Q9H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

470934:EGO56 RS18745
gene id: 470934:EGO56_RS18745
uniprot id: A0A7Z1Y6Q5
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

470934:EGO56 RS10075
gene id: 470934:EGO56_RS10075
uniprot id: A0A7Z1Y475
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

470934:EGO56 RS16750
gene id: 470934:EGO56_RS16750
uniprot id: A0A7Z2B501
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

470934:EGO56 RS11650
gene id: 470934:EGO56_RS11650
uniprot id: A0A7Z2B2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

470934:EGO56 RS17225
gene id: 470934:EGO56_RS17225
uniprot id: A0A7Z1Y5Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

470934:EGO56 RS17725
gene id: 470934:EGO56_RS17725
uniprot id: A0A7Z2B2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

470934:EGO56 RS13445
gene id: 470934:EGO56_RS13445
uniprot id: A0A7Z1Y4E2
names: Similarity
messages: Belongs to the MoaD family.

470934:EGO56 RS16225
gene id: 470934:EGO56_RS16225
uniprot id: A0A7Z1Y5R7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS08155
gene id: 470934:EGO56_RS08155
uniprot id: A0A1W9EW16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

470934:EGO56 RS07810
gene id: 470934:EGO56_RS07810
uniprot id: A0A7Z1Y3F1
names: Subcellular Location Annotation
messages: Cell inner membrane

470934:EGO56 RS18265
gene id: 470934:EGO56_RS18265
uniprot id: A0A7Z1Y626
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS18115
gene id: 470934:EGO56_RS18115
uniprot id: A0A7U4TA32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

470934:EGO56 RS01620
gene id: 470934:EGO56_RS01620
uniprot id: A0A5K5A8S4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS08515
gene id: 470934:EGO56_RS08515
uniprot id: A0A2R4J924
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

470934:EGO56 RS00550
gene id: 470934:EGO56_RS00550
uniprot id: A0A0X8Q312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

470934:EGO56 RS02730
gene id: 470934:EGO56_RS02730
uniprot id: A0A7Z1Y0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

470934:EGO56 RS11740
gene id: 470934:EGO56_RS11740
uniprot id: A0A7Z2B1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

470934:EGO56 RS01570
gene id: 470934:EGO56_RS01570
uniprot id: A0A7U4QAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

470934:EGO56 RS15940
gene id: 470934:EGO56_RS15940
uniprot id: A0A7Z2B3J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

470934:EGO56 RS20425
gene id: 470934:EGO56_RS20425
uniprot id: A0A7Z1Y752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS04470
gene id: 470934:EGO56_RS04470
uniprot id: A0A109YBW0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

470934:EGO56 RS02220
gene id: 470934:EGO56_RS02220
uniprot id: A0A0X8Q9R4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

470934:EGO56 RS04175
gene id: 470934:EGO56_RS04175
uniprot id: A0A7Z1Y169
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

470934:EGO56 RS02720
gene id: 470934:EGO56_RS02720
uniprot id: A0A7Z1Y0T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

470934:EGO56 RS18045
gene id: 470934:EGO56_RS18045
uniprot id: A0A7Z2B575
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

470934:EGO56 RS09945
gene id: 470934:EGO56_RS09945
uniprot id: A0A7Z1Y3H3
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS15885
gene id: 470934:EGO56_RS15885
uniprot id: A0A7Z1Y587
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

470934:EGO56 RS07570
gene id: 470934:EGO56_RS07570
uniprot id: A0A7Z1Y3C1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

470934:EGO56 RS15270
gene id: 470934:EGO56_RS15270
uniprot id: A0A7Z2B3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

470934:EGO56 RS15925
gene id: 470934:EGO56_RS15925
uniprot id: A0A7Z1Y5T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

470934:EGO56 RS13555
gene id: 470934:EGO56_RS13555
uniprot id: A0A7Z2B0F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS05995
gene id: 470934:EGO56_RS05995
uniprot id: A0A7U4Q948
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS03305
gene id: 470934:EGO56_RS03305
uniprot id: A0A7U4TCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

470934:EGO56 RS02870
gene id: 470934:EGO56_RS02870
uniprot id: A0A7Z1Y0Q2
names: Similarity
messages: Belongs to the UPF0307 family.

470934:EGO56 RS06220
gene id: 470934:EGO56_RS06220
uniprot id: A0A7Z1Y1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS00280
gene id: 470934:EGO56_RS00280
uniprot id: A0A2R4J3B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

470934:EGO56 RS00685
gene id: 470934:EGO56_RS00685
uniprot id: A0A501RY07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

470934:EGO56 RS13570
gene id: 470934:EGO56_RS13570
uniprot id: A0A7Z1Y5H6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

470934:EGO56 RS17865
gene id: 470934:EGO56_RS17865
uniprot id: A0A7Z2B570
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

470934:EGO56 RS10525
gene id: 470934:EGO56_RS10525
uniprot id: A0A7Z1Y3P2
names: Similarity
messages: Belongs to the glyoxalase I family.

470934:EGO56 RS14440
gene id: 470934:EGO56_RS14440
uniprot id: A0A7Z1Y4U9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS02540
gene id: 470934:EGO56_RS02540
uniprot id: A0A2R4J291
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

470934:EGO56 RS02600
gene id: 470934:EGO56_RS02600
uniprot id: A0A7Z2AZY5
names: Similarity
messages: Belongs to the barstar family.

470934:EGO56 RS08910
gene id: 470934:EGO56_RS08910
uniprot id: A0A7Z2B259
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS15910
gene id: 470934:EGO56_RS15910
uniprot id: A0A7Z1Y5N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

470934:EGO56 RS21310
gene id: 470934:EGO56_RS21310
uniprot id: A0A7Z2B210
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

470934:EGO56 RS13060
gene id: 470934:EGO56_RS13060
uniprot id: A0A7Z1Y4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS05930
gene id: 470934:EGO56_RS05930
uniprot id: A0A7U4TCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

470934:EGO56 RS15440
gene id: 470934:EGO56_RS15440
uniprot id: A0A7Z2B4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

470934:EGO56 RS07885
gene id: 470934:EGO56_RS07885
uniprot id: A0A7Z1Y6E0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

470934:EGO56 RS16030
gene id: 470934:EGO56_RS16030
uniprot id: A0A7Z1Y5B8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

470934:EGO56 RS06375
gene id: 470934:EGO56_RS06375
uniprot id: A0A7U4Q8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

470934:EGO56 RS05365
gene id: 470934:EGO56_RS05365
uniprot id: A0A7Z1Y1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

470934:EGO56 RS17330
gene id: 470934:EGO56_RS17330
uniprot id: A0A7U4Q5C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

470934:EGO56 RS17465
gene id: 470934:EGO56_RS17465
uniprot id: A0A7Z1Y671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS02235
gene id: 470934:EGO56_RS02235
uniprot id: A0A7U4TC51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

470934:EGO56 RS03920
gene id: 470934:EGO56_RS03920
uniprot id: A0A7Z1Y140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS10685
gene id: 470934:EGO56_RS10685
uniprot id: A0A7Z1Y3G7
names: Similarity
messages: Belongs to the peptidase C40 family.

470934:EGO56 RS07580
gene id: 470934:EGO56_RS07580
uniprot id: A0A7Z1Y2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

470934:EGO56 RS05530
gene id: 470934:EGO56_RS05530
uniprot id: A0A7U4TC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

470934:EGO56 RS15055
gene id: 470934:EGO56_RS15055
uniprot id: A0A7Z1Y507
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

470934:EGO56 RS08760
gene id: 470934:EGO56_RS08760
uniprot id: A0A7Z2B2B2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS12515
gene id: 470934:EGO56_RS12515
uniprot id: A0A0X8Q5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

470934:EGO56 RS02215
gene id: 470934:EGO56_RS02215
uniprot id: A0A0X8Q9W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

470934:EGO56 RS00045
gene id: 470934:EGO56_RS00045
uniprot id: A0A501S3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

470934:EGO56 RS04440
gene id: 470934:EGO56_RS04440
uniprot id: A0A7Z1Y192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

470934:EGO56 RS12975
gene id: 470934:EGO56_RS12975
uniprot id: A0A2R4J6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS03610
gene id: 470934:EGO56_RS03610
uniprot id: A0A7Z1Y0Z7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

470934:EGO56 RS10550
gene id: 470934:EGO56_RS10550
uniprot id: A0A7U4TB94
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

470934:EGO56 RS05040
gene id: 470934:EGO56_RS05040
uniprot id: A0A0X8Q8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

470934:EGO56 RS14295
gene id: 470934:EGO56_RS14295
uniprot id: A0A501SK94
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS01910
gene id: 470934:EGO56_RS01910
uniprot id: A0A7U4QAM8
names: Similarity
messages: Belongs to the HSP15 family.

470934:EGO56 RS00305
gene id: 470934:EGO56_RS00305
uniprot id: A0A2R4J3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

470934:EGO56 RS06270
gene id: 470934:EGO56_RS06270
uniprot id: A0A2R4JA97
names: Similarity
messages: Belongs to the elongation factor P family.

470934:EGO56 RS07830
gene id: 470934:EGO56_RS07830
uniprot id: A0A7Z1Y2L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

470934:EGO56 RS15695
gene id: 470934:EGO56_RS15695
uniprot id: A0A7Z2B3I1
names: Similarity
messages: Belongs to the UPF0231 family.

470934:EGO56 RS04460
gene id: 470934:EGO56_RS04460
uniprot id: A0A7U4Q9Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

470934:EGO56 RS02950
gene id: 470934:EGO56_RS02950
uniprot id: A0A7U4QAB4
names: Similarity
messages: Belongs to the UPF0102 family.

470934:EGO56 RS02240
gene id: 470934:EGO56_RS02240
uniprot id: A0A0X8Q9I3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

470934:EGO56 RS03135
gene id: 470934:EGO56_RS03135
uniprot id: A0A7Z1Y0Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

470934:EGO56 RS05160
gene id: 470934:EGO56_RS05160
uniprot id: A0A7Z2B1Q8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

470934:EGO56 RS20540
gene id: 470934:EGO56_RS20540
uniprot id: A0A7Z1Y7R4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

470934:EGO56 RS11795
gene id: 470934:EGO56_RS11795
uniprot id: A0A7U4TBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

470934:EGO56 RS03720
gene id: 470934:EGO56_RS03720
uniprot id: A0A7Z2B2R6
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

470934:EGO56 RS01880
gene id: 470934:EGO56_RS01880
uniprot id: A0A7Z2AYG1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

470934:EGO56 RS09475
gene id: 470934:EGO56_RS09475
uniprot id: A0A7Z2AZR0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS10475
gene id: 470934:EGO56_RS10475
uniprot id: A0A5K4YYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

470934:EGO56 RS09480
gene id: 470934:EGO56_RS09480
uniprot id: A0A7Z2B183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS13185
gene id: 470934:EGO56_RS13185
uniprot id: A0A7Z2B1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS16705
gene id: 470934:EGO56_RS16705
uniprot id: A0A7Z1Y6K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

470934:EGO56 RS14500
gene id: 470934:EGO56_RS14500
uniprot id: A0A7U4TA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS10115
gene id: 470934:EGO56_RS10115
uniprot id: A0A7Z1Y3J5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

470934:EGO56 RS08535
gene id: 470934:EGO56_RS08535
uniprot id: A0A7Z1Y3P7
names: Similarity
messages: Belongs to the UPF0260 family.

470934:EGO56 RS00495
gene id: 470934:EGO56_RS00495
uniprot id: A0A7Z1Y031
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

470934:EGO56 RS08425
gene id: 470934:EGO56_RS08425
uniprot id: A0A7Z2B3J2
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS09125
gene id: 470934:EGO56_RS09125
uniprot id: A0A7U4TBW4
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS03620
gene id: 470934:EGO56_RS03620
uniprot id: A0A7Z1Y118
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

470934:EGO56 RS12470
gene id: 470934:EGO56_RS12470
uniprot id: A0A7Z2B091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

470934:EGO56 RS08755
gene id: 470934:EGO56_RS08755
uniprot id: A0A7Z2B251
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS05805
gene id: 470934:EGO56_RS05805
uniprot id: A0A7Z2B0L0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

470934:EGO56 RS13815
gene id: 470934:EGO56_RS13815
uniprot id: A0A7Z2B208
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

470934:EGO56 RS16100
gene id: 470934:EGO56_RS16100
uniprot id: A0A7U4TAN6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

470934:EGO56 RS18125
gene id: 470934:EGO56_RS18125
uniprot id: A0A2R4J3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

470934:EGO56 RS17760
gene id: 470934:EGO56_RS17760
uniprot id: A0A7Z1Y682
names: Similarity
messages: Belongs to the transposase 8 family.

470934:EGO56 RS08795
gene id: 470934:EGO56_RS08795
uniprot id: A0A2R4J8X3
names: Similarity
messages: Belongs to the YciI family.

470934:EGO56 RS02735
gene id: 470934:EGO56_RS02735
uniprot id: A0A7Z1Y135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

470934:EGO56 RS00980
gene id: 470934:EGO56_RS00980
uniprot id: A0A7Z2B298
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

470934:EGO56 RS13235
gene id: 470934:EGO56_RS13235
uniprot id: A0A7Z1Y4Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

470934:EGO56 RS08375
gene id: 470934:EGO56_RS08375
uniprot id: A0A0X8Q7I9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS14680
gene id: 470934:EGO56_RS14680
uniprot id: A0A7Z1Y4V5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

470934:EGO56 RS02080
gene id: 470934:EGO56_RS02080
uniprot id: A0A7Z1Y0N7
names: Similarity
messages: Belongs to the phosphoribulokinase family.

470934:EGO56 RS02710
gene id: 470934:EGO56_RS02710
uniprot id: A0A7Z1Y0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.
messages: Membrane

470934:EGO56 RS01995
gene id: 470934:EGO56_RS01995
uniprot id: A0A7Z1Y0J5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

470934:EGO56 RS16145
gene id: 470934:EGO56_RS16145
uniprot id: A0A7U5TZ73
names: Function
names: Similarity
messages: Belongs to the thr operon leader peptide family.
messages: This protein is involved in control of the biosynthesis of threonine.

470934:EGO56 RS10210
gene id: 470934:EGO56_RS10210
uniprot id: A0A1W9EX85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

470934:EGO56 RS06485
gene id: 470934:EGO56_RS06485
uniprot id: A0A7Z1Y267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS07535
gene id: 470934:EGO56_RS07535
uniprot id: A0A7Z2B3D9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

470934:EGO56 RS18275
gene id: 470934:EGO56_RS18275
uniprot id: A0A120LNS4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

470934:EGO56 RS14880
gene id: 470934:EGO56_RS14880
uniprot id: A0A7Z2B3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

470934:EGO56 RS14775
gene id: 470934:EGO56_RS14775
uniprot id: A0A109YAJ9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

470934:EGO56 RS04930
gene id: 470934:EGO56_RS04930
uniprot id: A0A7Z2AYY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

470934:EGO56 RS11725
gene id: 470934:EGO56_RS11725
uniprot id: A0A7Z2B2N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

470934:EGO56 RS15825
gene id: 470934:EGO56_RS15825
uniprot id: A0A7U4Q5V6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

470934:EGO56 RS10960
gene id: 470934:EGO56_RS10960
uniprot id: A0A7Z1Y3T9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS16120
gene id: 470934:EGO56_RS16120
uniprot id: A0A7Z1Y5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

470934:EGO56 RS13160
gene id: 470934:EGO56_RS13160
uniprot id: A0A7Z1Y4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS13050
gene id: 470934:EGO56_RS13050
uniprot id: A0A7U4TB59
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

470934:EGO56 RS17845
gene id: 470934:EGO56_RS17845
uniprot id: A0A7Z1Y5Y5
names: Similarity
messages: Belongs to the Fur family.

470934:EGO56 RS03190
gene id: 470934:EGO56_RS03190
uniprot id: A0A7Z1Y1W4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

470934:EGO56 RS18475
gene id: 470934:EGO56_RS18475
uniprot id: A0A7Z1Y646
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

470934:EGO56 RS00710
gene id: 470934:EGO56_RS00710
uniprot id: A0A7Z1Y063
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

470934:EGO56 RS06645
gene id: 470934:EGO56_RS06645
uniprot id: A0A7Z1Y2A6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

470934:EGO56 RS08770
gene id: 470934:EGO56_RS08770
uniprot id: A0A7Z2B137
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS03245
gene id: 470934:EGO56_RS03245
uniprot id: A0A7Z2B184
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

470934:EGO56 RS13065
gene id: 470934:EGO56_RS13065
uniprot id: A0A7Z1Y4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS06005
gene id: 470934:EGO56_RS06005
uniprot id: A0A7Z1Y1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS04490
gene id: 470934:EGO56_RS04490
uniprot id: A0A7Z2B0D2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

470934:EGO56 RS05195
gene id: 470934:EGO56_RS05195
uniprot id: A0A7Z2B5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

470934:EGO56 RS18375
gene id: 470934:EGO56_RS18375
uniprot id: A0A7Z1Y6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

470934:EGO56 RS09035
gene id: 470934:EGO56_RS09035
uniprot id: A0A7U4Q8A1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS04210
gene id: 470934:EGO56_RS04210
uniprot id: A0A7Z2B2V0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

470934:EGO56 RS06390
gene id: 470934:EGO56_RS06390
uniprot id: A0A7Z1Y200
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

470934:EGO56 RS05405
gene id: 470934:EGO56_RS05405
uniprot id: A0A7U4Q9D2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

470934:EGO56 RS05480
gene id: 470934:EGO56_RS05480
uniprot id: A0A7Z2B0I8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS14770
gene id: 470934:EGO56_RS14770
uniprot id: A0A7Z1Y591
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

470934:EGO56 RS14675
gene id: 470934:EGO56_RS14675
uniprot id: A0A7Z1Y4X8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

470934:EGO56 RS12580
gene id: 470934:EGO56_RS12580
uniprot id: A0A7Z1Y482
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

470934:EGO56 RS06035
gene id: 470934:EGO56_RS06035
uniprot id: A0A2R4JAA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS18570
gene id: 470934:EGO56_RS18570
uniprot id: A0A7Z1Y6N7
names: Similarity
messages: Belongs to the peptidase M16 family.

470934:EGO56 RS15835
gene id: 470934:EGO56_RS15835
uniprot id: A0A7Z1Y5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

470934:EGO56 RS14430
gene id: 470934:EGO56_RS14430
uniprot id: A0A7Z1Y5Q3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

470934:EGO56 RS00920
gene id: 470934:EGO56_RS00920
uniprot id: A0A7Z2AYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

470934:EGO56 RS08570
gene id: 470934:EGO56_RS08570
uniprot id: A0A7Z1Y2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

470934:EGO56 RS08840
gene id: 470934:EGO56_RS08840
uniprot id: A0A7Z2B2B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

470934:EGO56 RS08175
gene id: 470934:EGO56_RS08175
uniprot id: A0A7Z2B213
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS14475
gene id: 470934:EGO56_RS14475
uniprot id: A0A0X8Q506
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

470934:EGO56 RS13460
gene id: 470934:EGO56_RS13460
uniprot id: A0A7Z1Y4S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

470934:EGO56 RS03780
gene id: 470934:EGO56_RS03780
uniprot id: A0A5K4Z3V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

470934:EGO56 RS00725
gene id: 470934:EGO56_RS00725
uniprot id: A0A7Z1Y037
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

470934:EGO56 RS02875
gene id: 470934:EGO56_RS02875
uniprot id: A0A7Z1Y0V9
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Probable metalloprotease.

470934:EGO56 RS08940
gene id: 470934:EGO56_RS08940
uniprot id: A0A7U4Q878
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

470934:EGO56 RS04965
gene id: 470934:EGO56_RS04965
uniprot id: A0A7Z1Y1D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

470934:EGO56 RS02115
gene id: 470934:EGO56_RS02115
uniprot id: A0A7Z2AZV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS08680
gene id: 470934:EGO56_RS08680
uniprot id: A0A109YBD1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

470934:EGO56 RS18085
gene id: 470934:EGO56_RS18085
uniprot id: A0A7Z1Y623
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

470934:EGO56 RS15575
gene id: 470934:EGO56_RS15575
uniprot id: A0A7Z1Y570
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

470934:EGO56 RS02620
gene id: 470934:EGO56_RS02620
uniprot id: A0A7U4TD66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

470934:EGO56 RS01145
gene id: 470934:EGO56_RS01145
uniprot id: A0A7Z1Y051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

470934:EGO56 RS03670
gene id: 470934:EGO56_RS03670
uniprot id: A0A7Z1Y222
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

470934:EGO56 RS02550
gene id: 470934:EGO56_RS02550
uniprot id: A0A7Z1Y0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

470934:EGO56 RS10730
gene id: 470934:EGO56_RS10730
uniprot id: A0A2R4J7S1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

470934:EGO56 RS01030
gene id: 470934:EGO56_RS01030
uniprot id: A0A7U4TA97
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

470934:EGO56 RS00460
gene id: 470934:EGO56_RS00460
uniprot id: A0A7Z1XZV4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

470934:EGO56 RS02260
gene id: 470934:EGO56_RS02260
uniprot id: A0A120LPP9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

470934:EGO56 RS12820
gene id: 470934:EGO56_RS12820
uniprot id: A0A7Z1Y4A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

470934:EGO56 RS11035
gene id: 470934:EGO56_RS11035
uniprot id: A0A7Z1Y3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

470934:EGO56 RS15265
gene id: 470934:EGO56_RS15265
uniprot id: A0A7Z2B4Q9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

470934:EGO56 RS05765
gene id: 470934:EGO56_RS05765
uniprot id: A0A7Z1Y1P0
names: Similarity
messages: Belongs to the MlaA family.

470934:EGO56 RS18095
gene id: 470934:EGO56_RS18095
uniprot id: A0A7Z1Y6C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

470934:EGO56 RS04630
gene id: 470934:EGO56_RS04630
uniprot id: A0A7U4Q9P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS16040
gene id: 470934:EGO56_RS16040
uniprot id: A0A7Z1Y5A6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

470934:EGO56 RS18110
gene id: 470934:EGO56_RS18110
uniprot id: A0A1W9EMM2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

470934:EGO56 RS09285
gene id: 470934:EGO56_RS09285
uniprot id: A0A7Z1Y300
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

470934:EGO56 RS15320
gene id: 470934:EGO56_RS15320
uniprot id: A0A7U4Q632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

470934:EGO56 RS02395
gene id: 470934:EGO56_RS02395
uniprot id: A0A7Z2B2I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

470934:EGO56 RS04390
gene id: 470934:EGO56_RS04390
uniprot id: A0A1W9ERQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

470934:EGO56 RS20295
gene id: 470934:EGO56_RS20295
uniprot id: A0A7Z1Y7B8
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS15470
gene id: 470934:EGO56_RS15470
uniprot id: A0A7Z1Y556
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

470934:EGO56 RS18240
gene id: 470934:EGO56_RS18240
uniprot id: A0A7U4Q542
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

470934:EGO56 RS17305
gene id: 470934:EGO56_RS17305
uniprot id: A0A109YA98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

470934:EGO56 RS12725
gene id: 470934:EGO56_RS12725
uniprot id: A0A7Z2B1U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

470934:EGO56 RS02990
gene id: 470934:EGO56_RS02990
uniprot id: A0A7Z2B2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

470934:EGO56 RS08365
gene id: 470934:EGO56_RS08365
uniprot id: A0A7Z2B115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

470934:EGO56 RS01895
gene id: 470934:EGO56_RS01895
uniprot id: A0A7Z1Y1B7
names: Subcellular Location Annotation
messages: Cell inner membrane

470934:EGO56 RS07555
gene id: 470934:EGO56_RS07555
uniprot id: A0A7U4TCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

470934:EGO56 RS18230
gene id: 470934:EGO56_RS18230
uniprot id: A0A7Z1Y6B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

470934:EGO56 RS06335
gene id: 470934:EGO56_RS06335
uniprot id: A0A7Z1Y296
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

470934:EGO56 RS04075
gene id: 470934:EGO56_RS04075
uniprot id: A0A7Z2AYU9
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

470934:EGO56 RS05270
gene id: 470934:EGO56_RS05270
uniprot id: A0A7Z1Y1I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

470934:EGO56 RS02815
gene id: 470934:EGO56_RS02815
uniprot id: A0A7Z1Y147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

470934:EGO56 RS05990
gene id: 470934:EGO56_RS05990
uniprot id: A0A7Z1Y1R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS00565
gene id: 470934:EGO56_RS00565
uniprot id: A0A7Z1Y014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

470934:EGO56 RS15830
gene id: 470934:EGO56_RS15830
uniprot id: A0A2R4J4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

470934:EGO56 RS00960
gene id: 470934:EGO56_RS00960
uniprot id: A0A0X8Q382
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

470934:EGO56 RS04675
gene id: 470934:EGO56_RS04675
uniprot id: A0A7Z2B0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

470934:EGO56 RS13985
gene id: 470934:EGO56_RS13985
uniprot id: A0A7Z2B332
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

470934:EGO56 RS07595
gene id: 470934:EGO56_RS07595
uniprot id: A0A0X8Q7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

470934:EGO56 RS07125
gene id: 470934:EGO56_RS07125
uniprot id: A0A7Z1Y2F2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS14495
gene id: 470934:EGO56_RS14495
uniprot id: A0A7Z2B3B8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

470934:EGO56 RS16065
gene id: 470934:EGO56_RS16065
uniprot id: A0A7Z1Y5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

470934:EGO56 RS18210
gene id: 470934:EGO56_RS18210
uniprot id: A0A7Z1Y629
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

470934:EGO56 RS03175
gene id: 470934:EGO56_RS03175
uniprot id: A0A7Z2AYP2
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS06040
gene id: 470934:EGO56_RS06040
uniprot id: A0A120LPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

470934:EGO56 RS15315
gene id: 470934:EGO56_RS15315
uniprot id: A0A7U4Q5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

470934:EGO56 RS17345
gene id: 470934:EGO56_RS17345
uniprot id: A0A1W9ER90
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

470934:EGO56 RS17715
gene id: 470934:EGO56_RS17715
uniprot id: A0A7Z2B3U2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

470934:EGO56 RS17860
gene id: 470934:EGO56_RS17860
uniprot id: A0A7Z1Y6F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

470934:EGO56 RS15455
gene id: 470934:EGO56_RS15455
uniprot id: A0A7Z2B2Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

470934:EGO56 RS17720
gene id: 470934:EGO56_RS17720
uniprot id: A0A7U4Q579
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

470934:EGO56 RS00310
gene id: 470934:EGO56_RS00310
uniprot id: A0A7U4T9X8
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS01800
gene id: 470934:EGO56_RS01800
uniprot id: A0A7Z2B151
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

470934:EGO56 RS02130
gene id: 470934:EGO56_RS02130
uniprot id: A0A7Z1Y0Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

470934:EGO56 RS00965
gene id: 470934:EGO56_RS00965
uniprot id: A0A501RXD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

470934:EGO56 RS07565
gene id: 470934:EGO56_RS07565
uniprot id: A0A2R4JCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

470934:EGO56 RS15935
gene id: 470934:EGO56_RS15935
uniprot id: A0A7Z2B3F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

470934:EGO56 RS07620
gene id: 470934:EGO56_RS07620
uniprot id: A0A7Z2B1X7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

470934:EGO56 RS00715
gene id: 470934:EGO56_RS00715
uniprot id: A0A7Z1XZY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

470934:EGO56 RS06330
gene id: 470934:EGO56_RS06330
uniprot id: A0A7Z1Y273
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

470934:EGO56 RS13535
gene id: 470934:EGO56_RS13535
uniprot id: A0A7U5Z4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

470934:EGO56 RS18410
gene id: 470934:EGO56_RS18410
uniprot id: A0A7Z2B3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

470934:EGO56 RS05440
gene id: 470934:EGO56_RS05440
uniprot id: A0A0X8Q8J5
names: Subcellular Location Annotation
messages: Cytoplasm

470934:EGO56 RS12430
gene id: 470934:EGO56_RS12430
uniprot id: A0A7Z1Y476
names: Subcellular Location Annotation
messages: Membrane

470934:EGO56 RS14605
gene id: 470934:EGO56_RS14605
uniprot id: A0A7U4TB84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane