469378:CCUR RS04365
gene id: 469378:CCUR_RS04365
uniprot id: C7MNU4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS05590
gene id: 469378:CCUR_RS05590
uniprot id: C7MPH7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

469378:CCUR RS03665
gene id: 469378:CCUR_RS03665
uniprot id: C7MNF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

469378:CCUR RS03900
gene id: 469378:CCUR_RS03900
uniprot id: C7MNK1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

469378:CCUR RS00910
gene id: 469378:CCUR_RS00910
uniprot id: C7MLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

469378:CCUR RS04845
gene id: 469378:CCUR_RS04845
uniprot id: C7MP32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

469378:CCUR RS04780
gene id: 469378:CCUR_RS04780
uniprot id: C7MP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

469378:CCUR RS05155
gene id: 469378:CCUR_RS05155
uniprot id: C7MP93
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

469378:CCUR RS05995
gene id: 469378:CCUR_RS05995
uniprot id: C7MKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

469378:CCUR RS03540
gene id: 469378:CCUR_RS03540
uniprot id: C7MND4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS02020
gene id: 469378:CCUR_RS02020
uniprot id: C7MMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469378:CCUR RS05980
gene id: 469378:CCUR_RS05980
uniprot id: C7MKU1
names: Subcellular Location Annotation
messages: Cytoplasm

469378:CCUR RS02595
gene id: 469378:CCUR_RS02595
uniprot id: C7MMV4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

469378:CCUR RS05495
gene id: 469378:CCUR_RS05495
uniprot id: C7MPF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

469378:CCUR RS00170
gene id: 469378:CCUR_RS00170
uniprot id: C7MLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

469378:CCUR RS04660
gene id: 469378:CCUR_RS04660
uniprot id: C7MP00
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

469378:CCUR RS05840
gene id: 469378:CCUR_RS05840
uniprot id: C7MPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

469378:CCUR RS06710
gene id: 469378:CCUR_RS06710
uniprot id: C7ML78
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

469378:CCUR RS00585
gene id: 469378:CCUR_RS00585
uniprot id: C7MLP7
names: Similarity
messages: Belongs to the HypD family.

469378:CCUR RS01010
gene id: 469378:CCUR_RS01010
uniprot id: C7MLZ7
names: Similarity
messages: Belongs to the AOR/FOR family.

469378:CCUR RS04135
gene id: 469378:CCUR_RS04135
uniprot id: C7MNP7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

469378:CCUR RS06250
gene id: 469378:CCUR_RS06250
uniprot id: C7MKZ2
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04565
gene id: 469378:CCUR_RS04565
uniprot id: C7MNY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

469378:CCUR RS01110
gene id: 469378:CCUR_RS01110
uniprot id: C7MM17
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

469378:CCUR RS06165
gene id: 469378:CCUR_RS06165
uniprot id: C7MKX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

469378:CCUR RS04085
gene id: 469378:CCUR_RS04085
uniprot id: C7MNN7
names: Similarity
messages: Belongs to the glutamine synthetase family.

469378:CCUR RS03535
gene id: 469378:CCUR_RS03535
uniprot id: C7MND3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

469378:CCUR RS04975
gene id: 469378:CCUR_RS04975
uniprot id: C7MP58
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

469378:CCUR RS06275
gene id: 469378:CCUR_RS06275
uniprot id: C7MKZ7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

469378:CCUR RS01190
gene id: 469378:CCUR_RS01190
uniprot id: C7MM31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

469378:CCUR RS06560
gene id: 469378:CCUR_RS06560
uniprot id: C7ML51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS03815
gene id: 469378:CCUR_RS03815
uniprot id: C7MNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

469378:CCUR RS02410
gene id: 469378:CCUR_RS02410
uniprot id: C7MMR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

469378:CCUR RS01640
gene id: 469378:CCUR_RS01640
uniprot id: C7MMB8
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03240
gene id: 469378:CCUR_RS03240
uniprot id: C7MN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

469378:CCUR RS03630
gene id: 469378:CCUR_RS03630
uniprot id: C7MNE8
names: Similarity
messages: Belongs to the peptidase S51 family.

469378:CCUR RS03760
gene id: 469378:CCUR_RS03760
uniprot id: C7MNH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

469378:CCUR RS00835
gene id: 469378:CCUR_RS00835
uniprot id: C7MLU7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

469378:CCUR RS04710
gene id: 469378:CCUR_RS04710
uniprot id: C7MP10
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS02190
gene id: 469378:CCUR_RS02190
uniprot id: C7MMM4
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03115
gene id: 469378:CCUR_RS03115
uniprot id: C7MN55
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

469378:CCUR RS03095
gene id: 469378:CCUR_RS03095
uniprot id: C7MN51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

469378:CCUR RS00775
gene id: 469378:CCUR_RS00775
uniprot id: C7MLT5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

469378:CCUR RS03140
gene id: 469378:CCUR_RS03140
uniprot id: C7MN60
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

469378:CCUR RS00050
gene id: 469378:CCUR_RS00050
uniprot id: C7MLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS06120
gene id: 469378:CCUR_RS06120
uniprot id: C7MKW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS07240
gene id: 469378:CCUR_RS07240
uniprot id: C7MNL0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS04390
gene id: 469378:CCUR_RS04390
uniprot id: C7MNU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS01060
gene id: 469378:CCUR_RS01060
uniprot id: C7MM07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

469378:CCUR RS04410
gene id: 469378:CCUR_RS04410
uniprot id: C7MNV2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

469378:CCUR RS05805
gene id: 469378:CCUR_RS05805
uniprot id: C7MPL4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

469378:CCUR RS05500
gene id: 469378:CCUR_RS05500
uniprot id: C7MPF9
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS06265
gene id: 469378:CCUR_RS06265
uniprot id: C7MKZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

469378:CCUR RS03510
gene id: 469378:CCUR_RS03510
uniprot id: C7MNC8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

469378:CCUR RS04990
gene id: 469378:CCUR_RS04990
uniprot id: C7MP61
names: Similarity
messages: Belongs to the universal stress protein A family.

469378:CCUR RS02130
gene id: 469378:CCUR_RS02130
uniprot id: C7MML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS03965
gene id: 469378:CCUR_RS03965
uniprot id: C7MNL4
names: Similarity
messages: Belongs to the ribF family.

469378:CCUR RS02950
gene id: 469378:CCUR_RS02950
uniprot id: C7MN23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

469378:CCUR RS03255
gene id: 469378:CCUR_RS03255
uniprot id: C7MN81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS05715
gene id: 469378:CCUR_RS05715
uniprot id: C7MPJ9
names: Similarity
messages: Belongs to the GARS family.

469378:CCUR RS06155
gene id: 469378:CCUR_RS06155
uniprot id: C7MKX5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

469378:CCUR RS06585
gene id: 469378:CCUR_RS06585
uniprot id: C7ML56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

469378:CCUR RS00460
gene id: 469378:CCUR_RS00460
uniprot id: C7MLM2
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS02420
gene id: 469378:CCUR_RS02420
uniprot id: C7MMR9
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04680
gene id: 469378:CCUR_RS04680
uniprot id: C7MP04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

469378:CCUR RS00405
gene id: 469378:CCUR_RS00405
uniprot id: C7MLL2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

469378:CCUR RS05860
gene id: 469378:CCUR_RS05860
uniprot id: C7MKR8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

469378:CCUR RS02230
gene id: 469378:CCUR_RS02230
uniprot id: C7MMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS06330
gene id: 469378:CCUR_RS06330
uniprot id: C7ML07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

469378:CCUR RS06440
gene id: 469378:CCUR_RS06440
uniprot id: C7ML27
names: Similarity
messages: Belongs to the DtxR/MntR family.

469378:CCUR RS04825
gene id: 469378:CCUR_RS04825
uniprot id: C7MP28
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

469378:CCUR RS02820
gene id: 469378:CCUR_RS02820
uniprot id: C7MMZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

469378:CCUR RS03765
gene id: 469378:CCUR_RS03765
uniprot id: C7MNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

469378:CCUR RS02175
gene id: 469378:CCUR_RS02175
uniprot id: C7MMM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

469378:CCUR RS00830
gene id: 469378:CCUR_RS00830
uniprot id: C7MLU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

469378:CCUR RS01875
gene id: 469378:CCUR_RS01875
uniprot id: C7MMG2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469378:CCUR RS01890
gene id: 469378:CCUR_RS01890
uniprot id: C7MMG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

469378:CCUR RS01900
gene id: 469378:CCUR_RS01900
uniprot id: C7MMG7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

469378:CCUR RS01835
gene id: 469378:CCUR_RS01835
uniprot id: C7MMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

469378:CCUR RS06730
gene id: 469378:CCUR_RS06730
uniprot id: C7ML82
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS02975
gene id: 469378:CCUR_RS02975
uniprot id: C7MN28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

469378:CCUR RS05565
gene id: 469378:CCUR_RS05565
uniprot id: C7MPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

469378:CCUR RS02600
gene id: 469378:CCUR_RS02600
uniprot id: C7MMV5
names: Similarity
messages: Belongs to the asp23 family.

469378:CCUR RS05320
gene id: 469378:CCUR_RS05320
uniprot id: C7MPC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

469378:CCUR RS02015
gene id: 469378:CCUR_RS02015
uniprot id: C7MMI9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

469378:CCUR RS00315
gene id: 469378:CCUR_RS00315
uniprot id: C7MLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

469378:CCUR RS04915
gene id: 469378:CCUR_RS04915
uniprot id: C7MP46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

469378:CCUR RS02920
gene id: 469378:CCUR_RS02920
uniprot id: C7MN17
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

469378:CCUR RS05830
gene id: 469378:CCUR_RS05830
uniprot id: C7MPL9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

469378:CCUR RS00115
gene id: 469378:CCUR_RS00115
uniprot id: C7MLF0
names: Similarity
messages: Belongs to the peptidase C69 family.

469378:CCUR RS04965
gene id: 469378:CCUR_RS04965
uniprot id: C7MP56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

469378:CCUR RS05955
gene id: 469378:CCUR_RS05955
uniprot id: C7MKT6
names: Similarity
messages: Belongs to the asparagine synthetase family.

469378:CCUR RS01865
gene id: 469378:CCUR_RS01865
uniprot id: C7MMG0
names: Similarity
messages: Belongs to the universal stress protein A family.

469378:CCUR RS03745
gene id: 469378:CCUR_RS03745
uniprot id: C7MNH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

469378:CCUR RS07285
gene id: 469378:CCUR_RS07285
uniprot id: C7MPD0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

469378:CCUR RS04035
gene id: 469378:CCUR_RS04035
uniprot id: C7MNM8
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03685
gene id: 469378:CCUR_RS03685
uniprot id: C7MNF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS05640
gene id: 469378:CCUR_RS05640
uniprot id: C7MPI5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

469378:CCUR RS03360
gene id: 469378:CCUR_RS03360
uniprot id: C7MN98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS00505
gene id: 469378:CCUR_RS00505
uniprot id: C7MLN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

469378:CCUR RS04705
gene id: 469378:CCUR_RS04705
uniprot id: C7MP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

469378:CCUR RS05735
gene id: 469378:CCUR_RS05735
uniprot id: C7MPK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

469378:CCUR RS06610
gene id: 469378:CCUR_RS06610
uniprot id: C7ML60
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS00265
gene id: 469378:CCUR_RS00265
uniprot id: C7MLI2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

469378:CCUR RS03025
gene id: 469378:CCUR_RS03025
uniprot id: C7MN37
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS00270
gene id: 469378:CCUR_RS00270
uniprot id: C7MLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

469378:CCUR RS01035
gene id: 469378:CCUR_RS01035
uniprot id: C7MM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

469378:CCUR RS06945
gene id: 469378:CCUR_RS06945
uniprot id: C7MLC4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

469378:CCUR RS00075
gene id: 469378:CCUR_RS00075
uniprot id: C7MLE2
names: Similarity
messages: Belongs to the asparaginase 1 family.

469378:CCUR RS04745
gene id: 469378:CCUR_RS04745
uniprot id: C7MP17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS04285
gene id: 469378:CCUR_RS04285
uniprot id: C7MNS9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

469378:CCUR RS04875
gene id: 469378:CCUR_RS04875
uniprot id: C7MP38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

469378:CCUR RS04645
gene id: 469378:CCUR_RS04645
uniprot id: C7MNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

469378:CCUR RS03415
gene id: 469378:CCUR_RS03415
uniprot id: C7MNA9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

469378:CCUR RS03555
gene id: 469378:CCUR_RS03555
uniprot id: C7MND7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

469378:CCUR RS03790
gene id: 469378:CCUR_RS03790
uniprot id: C7MNH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

469378:CCUR RS02235
gene id: 469378:CCUR_RS02235
uniprot id: C7MMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469378:CCUR RS06005
gene id: 469378:CCUR_RS06005
uniprot id: C7MKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

469378:CCUR RS07110
gene id: 469378:CCUR_RS07110
uniprot id: C7MLQ2
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS05520
gene id: 469378:CCUR_RS05520
uniprot id: C7MPG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

469378:CCUR RS04855
gene id: 469378:CCUR_RS04855
uniprot id: C7MP34
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

469378:CCUR RS06300
gene id: 469378:CCUR_RS06300
uniprot id: C7ML02
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04315
gene id: 469378:CCUR_RS04315
uniprot id: C7MNT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469378:CCUR RS06385
gene id: 469378:CCUR_RS06385
uniprot id: C7ML16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

469378:CCUR RS03655
gene id: 469378:CCUR_RS03655
uniprot id: C7MNF3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

469378:CCUR RS00455
gene id: 469378:CCUR_RS00455
uniprot id: C7MLM1
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03065
gene id: 469378:CCUR_RS03065
uniprot id: C7MN45
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

469378:CCUR RS05040
gene id: 469378:CCUR_RS05040
uniprot id: C7MP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS00160
gene id: 469378:CCUR_RS00160
uniprot id: C7MLF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

469378:CCUR RS02675
gene id: 469378:CCUR_RS02675
uniprot id: C7MMX0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

469378:CCUR RS05395
gene id: 469378:CCUR_RS05395
uniprot id: C7MPE0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS00725
gene id: 469378:CCUR_RS00725
uniprot id: C7MLS5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

469378:CCUR RS05890
gene id: 469378:CCUR_RS05890
uniprot id: C7MKS4
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS06655
gene id: 469378:CCUR_RS06655
uniprot id: C7ML68
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

469378:CCUR RS02200
gene id: 469378:CCUR_RS02200
uniprot id: C7MMM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS06295
gene id: 469378:CCUR_RS06295
uniprot id: C7ML01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

469378:CCUR RS06290
gene id: 469378:CCUR_RS06290
uniprot id: C7ML00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

469378:CCUR RS05720
gene id: 469378:CCUR_RS05720
uniprot id: C7MPK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

469378:CCUR RS03435
gene id: 469378:CCUR_RS03435
uniprot id: C7MNB3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS06650
gene id: 469378:CCUR_RS06650
uniprot id: C7ML67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

469378:CCUR RS06390
gene id: 469378:CCUR_RS06390
uniprot id: C7ML17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

469378:CCUR RS00465
gene id: 469378:CCUR_RS00465
uniprot id: C7MLM3
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03245
gene id: 469378:CCUR_RS03245
uniprot id: C7MN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

469378:CCUR RS04175
gene id: 469378:CCUR_RS04175
uniprot id: C7MNQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

469378:CCUR RS04545
gene id: 469378:CCUR_RS04545
uniprot id: C7MNX6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

469378:CCUR RS00575
gene id: 469378:CCUR_RS00575
uniprot id: C7MLP5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

469378:CCUR RS02095
gene id: 469378:CCUR_RS02095
uniprot id: C7MMK5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

469378:CCUR RS05790
gene id: 469378:CCUR_RS05790
uniprot id: C7MPL1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

469378:CCUR RS06720
gene id: 469378:CCUR_RS06720
uniprot id: C7ML80
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS05745
gene id: 469378:CCUR_RS05745
uniprot id: C7MPK5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

469378:CCUR RS05915
gene id: 469378:CCUR_RS05915
uniprot id: C7MKS8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

469378:CCUR RS04735
gene id: 469378:CCUR_RS04735
uniprot id: C7MP15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

469378:CCUR RS06950
gene id: 469378:CCUR_RS06950
uniprot id: C7MLC5
names: Similarity
messages: Belongs to the DDAH family.

469378:CCUR RS03615
gene id: 469378:CCUR_RS03615
uniprot id: C7MNE5
names: Similarity
messages: Belongs to the peptidase S11 family.

469378:CCUR RS02085
gene id: 469378:CCUR_RS02085
uniprot id: C7MMK3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

469378:CCUR RS04930
gene id: 469378:CCUR_RS04930
uniprot id: C7MP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

469378:CCUR RS04900
gene id: 469378:CCUR_RS04900
uniprot id: C7MP43
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

469378:CCUR RS04740
gene id: 469378:CCUR_RS04740
uniprot id: C7MP16
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS03705
gene id: 469378:CCUR_RS03705
uniprot id: C7MNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

469378:CCUR RS02955
gene id: 469378:CCUR_RS02955
uniprot id: C7MN24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

469378:CCUR RS06035
gene id: 469378:CCUR_RS06035
uniprot id: C7MKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS00010
gene id: 469378:CCUR_RS00010
uniprot id: C7MLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

469378:CCUR RS04700
gene id: 469378:CCUR_RS04700
uniprot id: C7MP08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

469378:CCUR RS04685
gene id: 469378:CCUR_RS04685
uniprot id: C7MP05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS01925
gene id: 469378:CCUR_RS01925
uniprot id: C7MMH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

469378:CCUR RS03700
gene id: 469378:CCUR_RS03700
uniprot id: C7MNG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

469378:CCUR RS03100
gene id: 469378:CCUR_RS03100
uniprot id: C7MN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

469378:CCUR RS04665
gene id: 469378:CCUR_RS04665
uniprot id: C7MP01
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

469378:CCUR RS00520
gene id: 469378:CCUR_RS00520
uniprot id: C7MLN4
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03805
gene id: 469378:CCUR_RS03805
uniprot id: C7MNI2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

469378:CCUR RS06405
gene id: 469378:CCUR_RS06405
uniprot id: C7ML20
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

469378:CCUR RS04770
gene id: 469378:CCUR_RS04770
uniprot id: C7MP21
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

469378:CCUR RS00515
gene id: 469378:CCUR_RS00515
uniprot id: C7MLN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

469378:CCUR RS04600
gene id: 469378:CCUR_RS04600
uniprot id: C7MNY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS00715
gene id: 469378:CCUR_RS00715
uniprot id: C7MLS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

469378:CCUR RS00340
gene id: 469378:CCUR_RS00340
uniprot id: C7MLJ9
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS02680
gene id: 469378:CCUR_RS02680
uniprot id: C7MMX1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

469378:CCUR RS05920
gene id: 469378:CCUR_RS05920
uniprot id: C7MKS9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

469378:CCUR RS06780
gene id: 469378:CCUR_RS06780
uniprot id: C7ML92
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

469378:CCUR RS07625
gene id: 469378:CCUR_RS07625
uniprot id: C7MNG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

469378:CCUR RS01710
gene id: 469378:CCUR_RS01710
uniprot id: C7MMD1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS05480
gene id: 469378:CCUR_RS05480
uniprot id: C7MPF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

469378:CCUR RS02405
gene id: 469378:CCUR_RS02405
uniprot id: C7MMR6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

469378:CCUR RS03585
gene id: 469378:CCUR_RS03585
uniprot id: C7MND9
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS01615
gene id: 469378:CCUR_RS01615
uniprot id: C7MMB3
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03830
gene id: 469378:CCUR_RS03830
uniprot id: C7MNI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

469378:CCUR RS01560
gene id: 469378:CCUR_RS01560
uniprot id: C7MMA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

469378:CCUR RS01680
gene id: 469378:CCUR_RS01680
uniprot id: C7MMC6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

469378:CCUR RS03720
gene id: 469378:CCUR_RS03720
uniprot id: C7MNG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

469378:CCUR RS03195
gene id: 469378:CCUR_RS03195
uniprot id: C7MN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

469378:CCUR RS03205
gene id: 469378:CCUR_RS03205
uniprot id: C7MN72
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

469378:CCUR RS03045
gene id: 469378:CCUR_RS03045
uniprot id: C7MN41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

469378:CCUR RS02035
gene id: 469378:CCUR_RS02035
uniprot id: C7MMJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS04670
gene id: 469378:CCUR_RS04670
uniprot id: C7MP02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

469378:CCUR RS00790
gene id: 469378:CCUR_RS00790
uniprot id: C7MLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

469378:CCUR RS01145
gene id: 469378:CCUR_RS01145
uniprot id: C7MM24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS00770
gene id: 469378:CCUR_RS00770
uniprot id: C7MLT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

469378:CCUR RS02805
gene id: 469378:CCUR_RS02805
uniprot id: C7MMZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

469378:CCUR RS03250
gene id: 469378:CCUR_RS03250
uniprot id: C7MN80
names: Similarity
messages: Belongs to the carbamate kinase family.

469378:CCUR RS04630
gene id: 469378:CCUR_RS04630
uniprot id: C7MNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

469378:CCUR RS06555
gene id: 469378:CCUR_RS06555
uniprot id: C7ML50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS04470
gene id: 469378:CCUR_RS04470
uniprot id: C7MNW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

469378:CCUR RS02560
gene id: 469378:CCUR_RS02560
uniprot id: C7MMU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS03865
gene id: 469378:CCUR_RS03865
uniprot id: C7MNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

469378:CCUR RS04850
gene id: 469378:CCUR_RS04850
uniprot id: C7MP33
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

469378:CCUR RS00025
gene id: 469378:CCUR_RS00025
uniprot id: C7MLD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

469378:CCUR RS04455
gene id: 469378:CCUR_RS04455
uniprot id: C7MNV9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

469378:CCUR RS05630
gene id: 469378:CCUR_RS05630
uniprot id: C7MPI3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

469378:CCUR RS06675
gene id: 469378:CCUR_RS06675
uniprot id: C7ML72
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

469378:CCUR RS05515
gene id: 469378:CCUR_RS05515
uniprot id: C7MPG2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

469378:CCUR RS03155
gene id: 469378:CCUR_RS03155
uniprot id: C7MN63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS02840
gene id: 469378:CCUR_RS02840
uniprot id: C7MN01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

469378:CCUR RS04650
gene id: 469378:CCUR_RS04650
uniprot id: C7MNZ8
names: Similarity
messages: Belongs to the YggT family.

469378:CCUR RS03150
gene id: 469378:CCUR_RS03150
uniprot id: C7MN62
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

469378:CCUR RS04950
gene id: 469378:CCUR_RS04950
uniprot id: C7MP53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

469378:CCUR RS04940
gene id: 469378:CCUR_RS04940
uniprot id: C7MP51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

469378:CCUR RS05570
gene id: 469378:CCUR_RS05570
uniprot id: C7MPH3
names: Similarity
messages: Belongs to the CsoR family.

469378:CCUR RS02830
gene id: 469378:CCUR_RS02830
uniprot id: C7MMZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

469378:CCUR RS03995
gene id: 469378:CCUR_RS03995
uniprot id: C7MNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

469378:CCUR RS06760
gene id: 469378:CCUR_RS06760
uniprot id: C7ML88
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

469378:CCUR RS01050
gene id: 469378:CCUR_RS01050
uniprot id: C7MM05
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

469378:CCUR RS03970
gene id: 469378:CCUR_RS03970
uniprot id: C7MNL5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

469378:CCUR RS03875
gene id: 469378:CCUR_RS03875
uniprot id: C7MNJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

469378:CCUR RS00740
gene id: 469378:CCUR_RS00740
uniprot id: C7MLS8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

469378:CCUR RS00295
gene id: 469378:CCUR_RS00295
uniprot id: C7MLI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

469378:CCUR RS00685
gene id: 469378:CCUR_RS00685
uniprot id: C7MLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

469378:CCUR RS04575
gene id: 469378:CCUR_RS04575
uniprot id: C7MNY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

469378:CCUR RS00760
gene id: 469378:CCUR_RS00760
uniprot id: C7MLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS05000
gene id: 469378:CCUR_RS05000
uniprot id: C7MP63
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

469378:CCUR RS02140
gene id: 469378:CCUR_RS02140
uniprot id: C7MML4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

469378:CCUR RS02180
gene id: 469378:CCUR_RS02180
uniprot id: C7MMM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS02730
gene id: 469378:CCUR_RS02730
uniprot id: C7MMY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

469378:CCUR RS06075
gene id: 469378:CCUR_RS06075
uniprot id: C7MKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

469378:CCUR RS05020
gene id: 469378:CCUR_RS05020
uniprot id: C7MP67
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

469378:CCUR RS06310
gene id: 469378:CCUR_RS06310
uniprot id: C7ML04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469378:CCUR RS04405
gene id: 469378:CCUR_RS04405
uniprot id: C7MNV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

469378:CCUR RS04320
gene id: 469378:CCUR_RS04320
uniprot id: C7MNT5
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS00940
gene id: 469378:CCUR_RS00940
uniprot id: C7MLY3
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS01105
gene id: 469378:CCUR_RS01105
uniprot id: C7MM16
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

469378:CCUR RS03015
gene id: 469378:CCUR_RS03015
uniprot id: C7MN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

469378:CCUR RS03340
gene id: 469378:CCUR_RS03340
uniprot id: C7MN94
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

469378:CCUR RS07045
gene id: 469378:CCUR_RS07045
uniprot id: C7MLX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

469378:CCUR RS04925
gene id: 469378:CCUR_RS04925
uniprot id: C7MP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

469378:CCUR RS04260
gene id: 469378:CCUR_RS04260
uniprot id: C7MNS3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

469378:CCUR RS03425
gene id: 469378:CCUR_RS03425
uniprot id: C7MNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

469378:CCUR RS00190
gene id: 469378:CCUR_RS00190
uniprot id: C7MLG5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

469378:CCUR RS06635
gene id: 469378:CCUR_RS06635
uniprot id: C7ML65
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

469378:CCUR RS01965
gene id: 469378:CCUR_RS01965
uniprot id: C7MMH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

469378:CCUR RS07360
gene id: 469378:CCUR_RS07360
uniprot id: C7MLC7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

469378:CCUR RS00680
gene id: 469378:CCUR_RS00680
uniprot id: C7MLR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469378:CCUR RS05390
gene id: 469378:CCUR_RS05390
uniprot id: C7MPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

469378:CCUR RS02990
gene id: 469378:CCUR_RS02990
uniprot id: C7MN30
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

469378:CCUR RS07210
gene id: 469378:CCUR_RS07210
uniprot id: C7MMM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

469378:CCUR RS05240
gene id: 469378:CCUR_RS05240
uniprot id: C7MPB0
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04360
gene id: 469378:CCUR_RS04360
uniprot id: C7MNU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

469378:CCUR RS02555
gene id: 469378:CCUR_RS02555
uniprot id: C7MMU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

469378:CCUR RS04420
gene id: 469378:CCUR_RS04420
uniprot id: C7MNV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS04220
gene id: 469378:CCUR_RS04220
uniprot id: C7MNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

469378:CCUR RS01075
gene id: 469378:CCUR_RS01075
uniprot id: C7MM10
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.

469378:CCUR RS00690
gene id: 469378:CCUR_RS00690
uniprot id: C7MLR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

469378:CCUR RS00895
gene id: 469378:CCUR_RS00895
uniprot id: C7MLV8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

469378:CCUR RS02650
gene id: 469378:CCUR_RS02650
uniprot id: C7MMW5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

469378:CCUR RS01910
gene id: 469378:CCUR_RS01910
uniprot id: C7MMG9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

469378:CCUR RS02105
gene id: 469378:CCUR_RS02105
uniprot id: C7MMK7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

469378:CCUR RS06215
gene id: 469378:CCUR_RS06215
uniprot id: C7MKY5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS03885
gene id: 469378:CCUR_RS03885
uniprot id: C7MNJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

469378:CCUR RS00615
gene id: 469378:CCUR_RS00615
uniprot id: C7MLQ3
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03440
gene id: 469378:CCUR_RS03440
uniprot id: C7MNB4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

469378:CCUR RS02980
gene id: 469378:CCUR_RS02980
uniprot id: C7MN29
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

469378:CCUR RS04765
gene id: 469378:CCUR_RS04765
uniprot id: C7MP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

469378:CCUR RS02375
gene id: 469378:CCUR_RS02375
uniprot id: C7MMR0
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04955
gene id: 469378:CCUR_RS04955
uniprot id: C7MP54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

469378:CCUR RS04865
gene id: 469378:CCUR_RS04865
uniprot id: C7MP36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

469378:CCUR RS05910
gene id: 469378:CCUR_RS05910
uniprot id: C7MKS7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

469378:CCUR RS00185
gene id: 469378:CCUR_RS00185
uniprot id: C7MLG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

469378:CCUR RS02000
gene id: 469378:CCUR_RS02000
uniprot id: C7MMI6
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04375
gene id: 469378:CCUR_RS04375
uniprot id: C7MNU6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

469378:CCUR RS05435
gene id: 469378:CCUR_RS05435
uniprot id: C7MPE8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

469378:CCUR RS05030
gene id: 469378:CCUR_RS05030
uniprot id: C7MP69
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

469378:CCUR RS06070
gene id: 469378:CCUR_RS06070
uniprot id: C7MKV9
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

469378:CCUR RS05055
gene id: 469378:CCUR_RS05055
uniprot id: C7MP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS04350
gene id: 469378:CCUR_RS04350
uniprot id: C7MNU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469378:CCUR RS05450
gene id: 469378:CCUR_RS05450
uniprot id: C7MPF1
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS00880
gene id: 469378:CCUR_RS00880
uniprot id: C7MLV5
names: Similarity
messages: Belongs to the peptidase M18 family.

469378:CCUR RS06030
gene id: 469378:CCUR_RS06030
uniprot id: C7MKV1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

469378:CCUR RS04905
gene id: 469378:CCUR_RS04905
uniprot id: C7MP44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

469378:CCUR RS02010
gene id: 469378:CCUR_RS02010
uniprot id: C7MMI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

469378:CCUR RS00305
gene id: 469378:CCUR_RS00305
uniprot id: C7MLJ1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

469378:CCUR RS03860
gene id: 469378:CCUR_RS03860
uniprot id: C7MNJ3
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

469378:CCUR RS06965
gene id: 469378:CCUR_RS06965
uniprot id: C7MLC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS04370
gene id: 469378:CCUR_RS04370
uniprot id: C7MNU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

469378:CCUR RS00700
gene id: 469378:CCUR_RS00700
uniprot id: C7MLR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

469378:CCUR RS06600
gene id: 469378:CCUR_RS06600
uniprot id: C7ML58
names: Similarity
messages: Belongs to the peptidase C40 family.

469378:CCUR RS02500
gene id: 469378:CCUR_RS02500
uniprot id: C7MMT5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

469378:CCUR RS00960
gene id: 469378:CCUR_RS00960
uniprot id: C7MLY7
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

469378:CCUR RS03530
gene id: 469378:CCUR_RS03530
uniprot id: C7MND2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

469378:CCUR RS01120
gene id: 469378:CCUR_RS01120
uniprot id: C7MM19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

469378:CCUR RS03315
gene id: 469378:CCUR_RS03315
uniprot id: C7MN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS04415
gene id: 469378:CCUR_RS04415
uniprot id: C7MNV3
names: Similarity
messages: Belongs to the thioredoxin family.

469378:CCUR RS03485
gene id: 469378:CCUR_RS03485
uniprot id: C7MNC3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

469378:CCUR RS02705
gene id: 469378:CCUR_RS02705
uniprot id: C7MMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

469378:CCUR RS00945
gene id: 469378:CCUR_RS00945
uniprot id: C7MLY4
names: Similarity
messages: Belongs to the amidinotransferase family.

469378:CCUR RS03675
gene id: 469378:CCUR_RS03675
uniprot id: C7MNF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

469378:CCUR RS03475
gene id: 469378:CCUR_RS03475
uniprot id: C7MNC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

469378:CCUR RS02670
gene id: 469378:CCUR_RS02670
uniprot id: C7MMW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS02755
gene id: 469378:CCUR_RS02755
uniprot id: C7MMY5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

469378:CCUR RS03710
gene id: 469378:CCUR_RS03710
uniprot id: C7MNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

469378:CCUR RS02335
gene id: 469378:CCUR_RS02335
uniprot id: C7MMQ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS04325
gene id: 469378:CCUR_RS04325
uniprot id: C7MNT6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469378:CCUR RS03505
gene id: 469378:CCUR_RS03505
uniprot id: C7MNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

469378:CCUR RS04775
gene id: 469378:CCUR_RS04775
uniprot id: C7MP22
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

469378:CCUR RS04340
gene id: 469378:CCUR_RS04340
uniprot id: C7MNT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

469378:CCUR RS02430
gene id: 469378:CCUR_RS02430
uniprot id: C7MMS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469378:CCUR RS04860
gene id: 469378:CCUR_RS04860
uniprot id: C7MP35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

469378:CCUR RS00155
gene id: 469378:CCUR_RS00155
uniprot id: C7MLF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

469378:CCUR RS03395
gene id: 469378:CCUR_RS03395
uniprot id: C7MNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

469378:CCUR RS06830
gene id: 469378:CCUR_RS06830
uniprot id: C7MLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

469378:CCUR RS03200
gene id: 469378:CCUR_RS03200
uniprot id: C7MN71
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

469378:CCUR RS04795
gene id: 469378:CCUR_RS04795
uniprot id: C7MP25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

469378:CCUR RS06280
gene id: 469378:CCUR_RS06280
uniprot id: C7MKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

469378:CCUR RS01970
gene id: 469378:CCUR_RS01970
uniprot id: C7MMI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

469378:CCUR RS03390
gene id: 469378:CCUR_RS03390
uniprot id: C7MNA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469378:CCUR RS07055
gene id: 469378:CCUR_RS07055
uniprot id: C7MLX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

469378:CCUR RS03330
gene id: 469378:CCUR_RS03330
uniprot id: C7MN92
names: Similarity
messages: Belongs to the DapA family.

469378:CCUR RS06770
gene id: 469378:CCUR_RS06770
uniprot id: C7ML90
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

469378:CCUR RS03550
gene id: 469378:CCUR_RS03550
uniprot id: C7MND6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

469378:CCUR RS06705
gene id: 469378:CCUR_RS06705
uniprot id: C7ML77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

469378:CCUR RS03470
gene id: 469378:CCUR_RS03470
uniprot id: C7MNC0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

469378:CCUR RS03525
gene id: 469378:CCUR_RS03525
uniprot id: C7MND1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

469378:CCUR RS02710
gene id: 469378:CCUR_RS02710
uniprot id: C7MMX6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

469378:CCUR RS03960
gene id: 469378:CCUR_RS03960
uniprot id: C7MNL3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

469378:CCUR RS04495
gene id: 469378:CCUR_RS04495
uniprot id: C7MNW6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

469378:CCUR RS02070
gene id: 469378:CCUR_RS02070
uniprot id: C7MMK0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

469378:CCUR RS06980
gene id: 469378:CCUR_RS06980
uniprot id: C7MLD1
names: Similarity
messages: Belongs to the isochorismate synthase family.

469378:CCUR RS02345
gene id: 469378:CCUR_RS02345
uniprot id: C7MMQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

469378:CCUR RS03645
gene id: 469378:CCUR_RS03645
uniprot id: C7MNF1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

469378:CCUR RS04200
gene id: 469378:CCUR_RS04200
uniprot id: C7MNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

469378:CCUR RS05385
gene id: 469378:CCUR_RS05385
uniprot id: C7MPD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

469378:CCUR RS00705
gene id: 469378:CCUR_RS00705
uniprot id: C7MLS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

469378:CCUR RS03880
gene id: 469378:CCUR_RS03880
uniprot id: C7MNJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

469378:CCUR RS00410
gene id: 469378:CCUR_RS00410
uniprot id: C7MLL3
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03005
gene id: 469378:CCUR_RS03005
uniprot id: C7MN33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

469378:CCUR RS00695
gene id: 469378:CCUR_RS00695
uniprot id: C7MLR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

469378:CCUR RS05825
gene id: 469378:CCUR_RS05825
uniprot id: C7MPL8
names: Similarity
messages: Belongs to the NAD synthetase family.

469378:CCUR RS04210
gene id: 469378:CCUR_RS04210
uniprot id: C7MNR3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

469378:CCUR RS01730
gene id: 469378:CCUR_RS01730
uniprot id: C7MMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

469378:CCUR RS06670
gene id: 469378:CCUR_RS06670
uniprot id: C7ML71
names: Similarity
messages: Belongs to the cytochrome c-552 family.

469378:CCUR RS05945
gene id: 469378:CCUR_RS05945
uniprot id: C7MKT4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

469378:CCUR RS02210
gene id: 469378:CCUR_RS02210
uniprot id: C7MMM8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS05740
gene id: 469378:CCUR_RS05740
uniprot id: C7MPK4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

469378:CCUR RS00955
gene id: 469378:CCUR_RS00955
uniprot id: C7MLY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

469378:CCUR RS06605
gene id: 469378:CCUR_RS06605
uniprot id: C7ML59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

469378:CCUR RS04460
gene id: 469378:CCUR_RS04460
uniprot id: C7MNW0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

469378:CCUR RS03775
gene id: 469378:CCUR_RS03775
uniprot id: C7MNH6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

469378:CCUR RS06540
gene id: 469378:CCUR_RS06540
uniprot id: C7ML47
names: Similarity
messages: Belongs to the GSP E family.

469378:CCUR RS06530
gene id: 469378:CCUR_RS06530
uniprot id: C7ML45
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS06715
gene id: 469378:CCUR_RS06715
uniprot id: C7ML79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS03635
gene id: 469378:CCUR_RS03635
uniprot id: C7MNE9
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS01895
gene id: 469378:CCUR_RS01895
uniprot id: C7MMG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

469378:CCUR RS00905
gene id: 469378:CCUR_RS00905
uniprot id: C7MLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

469378:CCUR RS04125
gene id: 469378:CCUR_RS04125
uniprot id: C7MNP5
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

469378:CCUR RS02620
gene id: 469378:CCUR_RS02620
uniprot id: C7MMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS04245
gene id: 469378:CCUR_RS04245
uniprot id: C7MNS0
names: Similarity
messages: Belongs to the Nth/MutY family.

469378:CCUR RS05865
gene id: 469378:CCUR_RS05865
uniprot id: C7MKR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

469378:CCUR RS03600
gene id: 469378:CCUR_RS03600
uniprot id: C7MNE2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

469378:CCUR RS02570
gene id: 469378:CCUR_RS02570
uniprot id: C7MMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

469378:CCUR RS04910
gene id: 469378:CCUR_RS04910
uniprot id: C7MP45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

469378:CCUR RS01100
gene id: 469378:CCUR_RS01100
uniprot id: C7MM15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS00240
gene id: 469378:CCUR_RS00240
uniprot id: C7MLH7
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

469378:CCUR RS02445
gene id: 469378:CCUR_RS02445
uniprot id: C7MMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

469378:CCUR RS04945
gene id: 469378:CCUR_RS04945
uniprot id: C7MP52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

469378:CCUR RS04205
gene id: 469378:CCUR_RS04205
uniprot id: C7MNR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

469378:CCUR RS00330
gene id: 469378:CCUR_RS00330
uniprot id: C7MLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

469378:CCUR RS01085
gene id: 469378:CCUR_RS01085
uniprot id: C7MM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

469378:CCUR RS03405
gene id: 469378:CCUR_RS03405
uniprot id: C7MNA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

469378:CCUR RS06190
gene id: 469378:CCUR_RS06190
uniprot id: C7MKY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

469378:CCUR RS04880
gene id: 469378:CCUR_RS04880
uniprot id: C7MP39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

469378:CCUR RS02635
gene id: 469378:CCUR_RS02635
uniprot id: C7MMW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

469378:CCUR RS00815
gene id: 469378:CCUR_RS00815
uniprot id: C7MLU3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

469378:CCUR RS05350
gene id: 469378:CCUR_RS05350
uniprot id: C7MPD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

469378:CCUR RS00475
gene id: 469378:CCUR_RS00475
uniprot id: C7MLM5
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS05975
gene id: 469378:CCUR_RS05975
uniprot id: C7MKU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS05405
gene id: 469378:CCUR_RS05405
uniprot id: C7MPE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

469378:CCUR RS04395
gene id: 469378:CCUR_RS04395
uniprot id: C7MNU9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

469378:CCUR RS04920
gene id: 469378:CCUR_RS04920
uniprot id: C7MP47
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

469378:CCUR RS06090
gene id: 469378:CCUR_RS06090
uniprot id: C7MKW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS01455
gene id: 469378:CCUR_RS01455
uniprot id: C7MM82
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

469378:CCUR RS06775
gene id: 469378:CCUR_RS06775
uniprot id: C7ML91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

469378:CCUR RS04345
gene id: 469378:CCUR_RS04345
uniprot id: C7MNU0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

469378:CCUR RS04895
gene id: 469378:CCUR_RS04895
uniprot id: C7MP42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

469378:CCUR RS03280
gene id: 469378:CCUR_RS03280
uniprot id: C7MN83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

469378:CCUR RS01930
gene id: 469378:CCUR_RS01930
uniprot id: C7MMH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

469378:CCUR RS00300
gene id: 469378:CCUR_RS00300
uniprot id: C7MLI9
names: Similarity
messages: Belongs to the HypE family.

469378:CCUR RS00605
gene id: 469378:CCUR_RS00605
uniprot id: C7MLQ1
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS05075
gene id: 469378:CCUR_RS05075
uniprot id: C7MP78
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

469378:CCUR RS03895
gene id: 469378:CCUR_RS03895
uniprot id: C7MNK0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

469378:CCUR RS05880
gene id: 469378:CCUR_RS05880
uniprot id: C7MKS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

469378:CCUR RS04400
gene id: 469378:CCUR_RS04400
uniprot id: C7MNV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

469378:CCUR RS06220
gene id: 469378:CCUR_RS06220
uniprot id: C7MKY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS03145
gene id: 469378:CCUR_RS03145
uniprot id: C7MN61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

469378:CCUR RS04225
gene id: 469378:CCUR_RS04225
uniprot id: C7MNR6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

469378:CCUR RS02005
gene id: 469378:CCUR_RS02005
uniprot id: C7MMI7
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

469378:CCUR RS04190
gene id: 469378:CCUR_RS04190
uniprot id: C7MNQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS06335
gene id: 469378:CCUR_RS06335
uniprot id: C7ML08
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

469378:CCUR RS02580
gene id: 469378:CCUR_RS02580
uniprot id: C7MMV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

469378:CCUR RS07015
gene id: 469378:CCUR_RS07015
uniprot id: C7MLW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

469378:CCUR RS03660
gene id: 469378:CCUR_RS03660
uniprot id: C7MNF4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

469378:CCUR RS07270
gene id: 469378:CCUR_RS07270
uniprot id: C7MP59
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS00965
gene id: 469378:CCUR_RS00965
uniprot id: C7MLY8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

469378:CCUR RS03110
gene id: 469378:CCUR_RS03110
uniprot id: C7MN54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

469378:CCUR RS06370
gene id: 469378:CCUR_RS06370
uniprot id: C7ML13
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

469378:CCUR RS04265
gene id: 469378:CCUR_RS04265
uniprot id: C7MNS5
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS03810
gene id: 469378:CCUR_RS03810
uniprot id: C7MNI3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

469378:CCUR RS02250
gene id: 469378:CCUR_RS02250
uniprot id: C7MMN6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

469378:CCUR RS04075
gene id: 469378:CCUR_RS04075
uniprot id: C7MNN5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

469378:CCUR RS06795
gene id: 469378:CCUR_RS06795
uniprot id: C7ML95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

469378:CCUR RS05795
gene id: 469378:CCUR_RS05795
uniprot id: C7MPL2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

469378:CCUR RS00195
gene id: 469378:CCUR_RS00195
uniprot id: C7MLG6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

469378:CCUR RS00580
gene id: 469378:CCUR_RS00580
uniprot id: C7MLP6
names: Similarity
messages: Belongs to the HupF/HypC family.

469378:CCUR RS03455
gene id: 469378:CCUR_RS03455
uniprot id: C7MNB7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

469378:CCUR RS00655
gene id: 469378:CCUR_RS00655
uniprot id: C7MLR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

469378:CCUR RS03800
gene id: 469378:CCUR_RS03800
uniprot id: C7MNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

469378:CCUR RS00970
gene id: 469378:CCUR_RS00970
uniprot id: C7MLY9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

469378:CCUR RS05950
gene id: 469378:CCUR_RS05950
uniprot id: C7MKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

469378:CCUR RS05410
gene id: 469378:CCUR_RS05410
uniprot id: C7MPE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

469378:CCUR RS06480
gene id: 469378:CCUR_RS06480
uniprot id: C7ML35
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

469378:CCUR RS01760
gene id: 469378:CCUR_RS01760
uniprot id: C7MME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

469378:CCUR RS06125
gene id: 469378:CCUR_RS06125
uniprot id: C7MKW9
names: Similarity
messages: Belongs to the Ahb/Nir family.

469378:CCUR RS02185
gene id: 469378:CCUR_RS02185
uniprot id: C7MMM3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

469378:CCUR RS06150
gene id: 469378:CCUR_RS06150
uniprot id: C7MKX4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

469378:CCUR RS02810
gene id: 469378:CCUR_RS02810
uniprot id: C7MMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

469378:CCUR RS03060
gene id: 469378:CCUR_RS03060
uniprot id: C7MN44
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

469378:CCUR RS06135
gene id: 469378:CCUR_RS06135
uniprot id: C7MKX1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

469378:CCUR RS00110
gene id: 469378:CCUR_RS00110
uniprot id: C7MLE9
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

469378:CCUR RS03650
gene id: 469378:CCUR_RS03650
uniprot id: C7MNF2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

469378:CCUR RS03940
gene id: 469378:CCUR_RS03940
uniprot id: C7MNK9
names: Similarity
messages: Belongs to the FBPase class 2 family.

469378:CCUR RS03625
gene id: 469378:CCUR_RS03625
uniprot id: C7MNE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

469378:CCUR RS03785
gene id: 469378:CCUR_RS03785
uniprot id: C7MNH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

469378:CCUR RS03985
gene id: 469378:CCUR_RS03985
uniprot id: C7MNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

469378:CCUR RS00710
gene id: 469378:CCUR_RS00710
uniprot id: C7MLS1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

469378:CCUR RS02735
gene id: 469378:CCUR_RS02735
uniprot id: C7MMY1
names: Similarity
messages: Belongs to the peptidase S41A family.

469378:CCUR RS00070
gene id: 469378:CCUR_RS00070
uniprot id: C7MLE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

469378:CCUR RS04040
gene id: 469378:CCUR_RS04040
uniprot id: C7MNM9
names: Similarity
messages: Belongs to the Dps family.

469378:CCUR RS00175
gene id: 469378:CCUR_RS00175
uniprot id: C7MLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

469378:CCUR RS00540
gene id: 469378:CCUR_RS00540
uniprot id: C7MLN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

469378:CCUR RS00785
gene id: 469378:CCUR_RS00785
uniprot id: C7MLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

469378:CCUR RS00335
gene id: 469378:CCUR_RS00335
uniprot id: C7MLJ7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

469378:CCUR RS03950
gene id: 469378:CCUR_RS03950
uniprot id: C7MNL1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

469378:CCUR RS06020
gene id: 469378:CCUR_RS06020
uniprot id: C7MKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

469378:CCUR RS02845
gene id: 469378:CCUR_RS02845
uniprot id: C7MN02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

469378:CCUR RS00310
gene id: 469378:CCUR_RS00310
uniprot id: C7MLJ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

469378:CCUR RS00800
gene id: 469378:CCUR_RS00800
uniprot id: C7MLU0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

469378:CCUR RS05780
gene id: 469378:CCUR_RS05780
uniprot id: C7MPK9
names: Similarity
messages: Belongs to the UPF0237 family.

469378:CCUR RS03890
gene id: 469378:CCUR_RS03890
uniprot id: C7MNJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

469378:CCUR RS02535
gene id: 469378:CCUR_RS02535
uniprot id: C7MMU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

469378:CCUR RS00470
gene id: 469378:CCUR_RS00470
uniprot id: C7MLM4
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS05730
gene id: 469378:CCUR_RS05730
uniprot id: C7MPK2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

469378:CCUR RS00005
gene id: 469378:CCUR_RS00005
uniprot id: C7MLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

469378:CCUR RS06430
gene id: 469378:CCUR_RS06430
uniprot id: C7ML25
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS04465
gene id: 469378:CCUR_RS04465
uniprot id: C7MNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

469378:CCUR RS03305
gene id: 469378:CCUR_RS03305
uniprot id: C7MN87
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

469378:CCUR RS05200
gene id: 469378:CCUR_RS05200
uniprot id: C7MPA2
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS04105
gene id: 469378:CCUR_RS04105
uniprot id: C7MNP1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

469378:CCUR RS07250
gene id: 469378:CCUR_RS07250
uniprot id: C7MNP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

469378:CCUR RS06285
gene id: 469378:CCUR_RS06285
uniprot id: C7MKZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

469378:CCUR RS04830
gene id: 469378:CCUR_RS04830
uniprot id: C7MP29
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

469378:CCUR RS05185
gene id: 469378:CCUR_RS05185
uniprot id: C7MP99
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

469378:CCUR RS00095
gene id: 469378:CCUR_RS00095
uniprot id: C7MLE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

469378:CCUR RS06580
gene id: 469378:CCUR_RS06580
uniprot id: C7ML55
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

469378:CCUR RS07120
gene id: 469378:CCUR_RS07120
uniprot id: C7MLT3
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

469378:CCUR RS00165
gene id: 469378:CCUR_RS00165
uniprot id: C7MLG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

469378:CCUR RS05990
gene id: 469378:CCUR_RS05990
uniprot id: C7MKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

469378:CCUR RS06750
gene id: 469378:CCUR_RS06750
uniprot id: C7ML86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

469378:CCUR RS04840
gene id: 469378:CCUR_RS04840
uniprot id: C7MP31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

469378:CCUR RS03955
gene id: 469378:CCUR_RS03955
uniprot id: C7MNL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

469378:CCUR RS03300
gene id: 469378:CCUR_RS03300
uniprot id: C7MN86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

469378:CCUR RS01975
gene id: 469378:CCUR_RS01975
uniprot id: C7MMI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

469378:CCUR RS06415
gene id: 469378:CCUR_RS06415
uniprot id: C7ML22
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

469378:CCUR RS04060
gene id: 469378:CCUR_RS04060
uniprot id: C7MNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

469378:CCUR RS04970
gene id: 469378:CCUR_RS04970
uniprot id: C7MP57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

469378:CCUR RS02370
gene id: 469378:CCUR_RS02370
uniprot id: C7MMQ9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

469378:CCUR RS06975
gene id: 469378:CCUR_RS06975
uniprot id: C7MLD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

469378:CCUR RS07330
gene id: 469378:CCUR_RS07330
uniprot id: C7ML46
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS02960
gene id: 469378:CCUR_RS02960
uniprot id: C7MN25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS07220
gene id: 469378:CCUR_RS07220
uniprot id: C7MMV7
names: Similarity
messages: Belongs to the XseB family.

469378:CCUR RS06095
gene id: 469378:CCUR_RS06095
uniprot id: C7MKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

469378:CCUR RS05660
gene id: 469378:CCUR_RS05660
uniprot id: C7MPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

469378:CCUR RS07020
gene id: 469378:CCUR_RS07020
uniprot id: C7MLW9
names: Subcellular Location Annotation
messages: Cytoplasm

469378:CCUR RS00805
gene id: 469378:CCUR_RS00805
uniprot id: C7MLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

469378:CCUR RS02115
gene id: 469378:CCUR_RS02115
uniprot id: C7MMK9
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS00430
gene id: 469378:CCUR_RS00430
uniprot id: C7MLL7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

469378:CCUR RS06745
gene id: 469378:CCUR_RS06745
uniprot id: C7ML85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS03350
gene id: 469378:CCUR_RS03350
uniprot id: C7MN96
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

469378:CCUR RS00380
gene id: 469378:CCUR_RS00380
uniprot id: C7MLK7
names: Similarity
messages: Belongs to the IMPACT family.

469378:CCUR RS06955
gene id: 469378:CCUR_RS06955
uniprot id: C7MLC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

469378:CCUR RS01235
gene id: 469378:CCUR_RS01235
uniprot id: C7MM40
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

469378:CCUR RS00810
gene id: 469378:CCUR_RS00810
uniprot id: C7MLU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

469378:CCUR RS02770
gene id: 469378:CCUR_RS02770
uniprot id: C7MMY8
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

469378:CCUR RS02330
gene id: 469378:CCUR_RS02330
uniprot id: C7MMQ1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

469378:CCUR RS04815
gene id: 469378:CCUR_RS04815
uniprot id: C7MP26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

469378:CCUR RS02760
gene id: 469378:CCUR_RS02760
uniprot id: C7MMY6
names: Similarity
messages: Belongs to the asp23 family.

469378:CCUR RS03500
gene id: 469378:CCUR_RS03500
uniprot id: C7MNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

469378:CCUR RS01185
gene id: 469378:CCUR_RS01185
uniprot id: C7MM30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

469378:CCUR RS05065
gene id: 469378:CCUR_RS05065
uniprot id: C7MP76
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS02205
gene id: 469378:CCUR_RS02205
uniprot id: C7MMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS01935
gene id: 469378:CCUR_RS01935
uniprot id: C7MMH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

469378:CCUR RS01620
gene id: 469378:CCUR_RS01620
uniprot id: C7MMB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469378:CCUR RS02525
gene id: 469378:CCUR_RS02525
uniprot id: C7MMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

469378:CCUR RS03460
gene id: 469378:CCUR_RS03460
uniprot id: C7MNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

469378:CCUR RS02780
gene id: 469378:CCUR_RS02780
uniprot id: C7MMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

469378:CCUR RS01055
gene id: 469378:CCUR_RS01055
uniprot id: C7MM06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

469378:CCUR RS03835
gene id: 469378:CCUR_RS03835
uniprot id: C7MNI8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

469378:CCUR RS03780
gene id: 469378:CCUR_RS03780
uniprot id: C7MNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

469378:CCUR RS06595
gene id: 469378:CCUR_RS06595
uniprot id: C7ML57
names: Similarity
messages: Belongs to the peptidase C40 family.

469378:CCUR RS07565
gene id: 469378:CCUR_RS07565
uniprot id: C7ML34
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

469378:CCUR RS02150
gene id: 469378:CCUR_RS02150
uniprot id: C7MML6
names: Similarity
messages: Belongs to the Fur family.

469378:CCUR RS07660
gene id: 469378:CCUR_RS07660
uniprot id: C7ML54
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

469378:CCUR RS00650
gene id: 469378:CCUR_RS00650
uniprot id: C7MLR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

469378:CCUR RS02485
gene id: 469378:CCUR_RS02485
uniprot id: C7MMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

469378:CCUR RS04335
gene id: 469378:CCUR_RS04335
uniprot id: C7MNT8
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

469378:CCUR RS06040
gene id: 469378:CCUR_RS06040
uniprot id: C7MKV3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

469378:CCUR RS04960
gene id: 469378:CCUR_RS04960
uniprot id: C7MP55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

469378:CCUR RS06380
gene id: 469378:CCUR_RS06380
uniprot id: C7ML15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

469378:CCUR RS02745
gene id: 469378:CCUR_RS02745
uniprot id: C7MMY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

469378:CCUR RS03545
gene id: 469378:CCUR_RS03545
uniprot id: C7MND5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

469378:CCUR RS01195
gene id: 469378:CCUR_RS01195
uniprot id: C7MM32
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

469378:CCUR RS05835
gene id: 469378:CCUR_RS05835
uniprot id: C7MPM0
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

469378:CCUR RS00630
gene id: 469378:CCUR_RS00630
uniprot id: C7MLQ6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

469378:CCUR RS04890
gene id: 469378:CCUR_RS04890
uniprot id: C7MP41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

469378:CCUR RS02475
gene id: 469378:CCUR_RS02475
uniprot id: C7MMT0
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

469378:CCUR RS04165
gene id: 469378:CCUR_RS04165
uniprot id: C7MNQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

469378:CCUR RS02380
gene id: 469378:CCUR_RS02380
uniprot id: C7MMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

469378:CCUR RS05050
gene id: 469378:CCUR_RS05050
uniprot id: C7MP73
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

469378:CCUR RS03000
gene id: 469378:CCUR_RS03000
uniprot id: C7MN32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

469378:CCUR RS04585
gene id: 469378:CCUR_RS04585
uniprot id: C7MNY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

469378:CCUR RS02625
gene id: 469378:CCUR_RS02625
uniprot id: C7MMW0
names: Similarity
messages: Belongs to the peptidase A24 family.

469378:CCUR RS01595
gene id: 469378:CCUR_RS01595
uniprot id: C7MMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

469378:CCUR RS03725
gene id: 469378:CCUR_RS03725
uniprot id: C7MNG7
names: Similarity
messages: Belongs to the UPF0234 family.

469378:CCUR RS01855
gene id: 469378:CCUR_RS01855
uniprot id: C7MMF9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

469378:CCUR RS04305
gene id: 469378:CCUR_RS04305
uniprot id: C7MNT2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

469378:CCUR RS05440
gene id: 469378:CCUR_RS05440
uniprot id: C7MPE9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

469378:CCUR RS02880
gene id: 469378:CCUR_RS02880
uniprot id: C7MN09
names: Similarity
messages: Belongs to the polysaccharide synthase family.

469378:CCUR RS04870
gene id: 469378:CCUR_RS04870
uniprot id: C7MP37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

469378:CCUR RS01660
gene id: 469378:CCUR_RS01660
uniprot id: C7MMC2
names: Subcellular Location Annotation
messages: Membrane

469378:CCUR RS05430
gene id: 469378:CCUR_RS05430
uniprot id: C7MPE7
names: Similarity
messages: Belongs to the ArsC family.

469378:CCUR RS04590
gene id: 469378:CCUR_RS04590
uniprot id: C7MNY6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.